ライフサイエンスコーパス: MST

1 MST kinases are emerging as key signaling molecules that

2 MST-312 also inhibited the replication of HSV-2 and a re

3 MST-312 treatment reduced the number of cells displaying

4 MSTd neurons also show significant correlations with per

5 MSTs [Pediatric Yorkhill Malnutrition Score (PYMS), Scre

6 MSTs performed differently in associations to BC/anthrop

7 CSE and 3-MST are expressed in the human microvasculature.

8 CSE and 3-MST were expressed in all skin samples.

9 CSE and 3-MST were quantified in forearm skin samples from 5 healt

10 drial H(2)S-producing pathway, governed by 3-MST, complements and balances the bioenergetic role of K

11 SiRNA silencing of 3-MST reduced basal bioenergetic parameters and prevented

12 zyme 3-mercaptopyruvate sulfurtransferase (3-MST) stimulated mitochondrial H(2)S production and enhan

13 and 3-mercaptopyruvate sulfurtransferase (3-MST), in comparison to adjacent lung tissue.

14 and 3-mercaptopyruvate sulphurtransferase (3-MST), which endogenously produce hydrogen sulphide (H2 S

15 h varying hydrogeological properties using a MST toolbox containing two bacteriophage groups (phage i

16 Feedback from the most active MSTd cell subpopulations suppresses motion signals in MT

17 ly different than the renal transplant alone MST (85 days, p = 0.46), with histopathology documenting

18 the number and configurations of alternative MSTs, and allows identification of the most credible MST

19 roximates a multiplicative interaction among MST inputs.

20 hether recurrent, competitive dynamics among MSTd neurons that serve to reduce uncertainty about head

21 Cells are first grouped into clusters and an MST is then constructed to connect cluster centers.

22 s branch point transform chorismate using an MST enzyme.

23 We find BIBR-1532 (2) and MST-312 (5) inhibit only human telomerase, whereas beta-

24 ms of division location, cleavage angle, and MST distance, as well as fiber orientation and dynamics.

25 native to empirical ST titration for ECT and MST.

26 al role of these models in dosing of ECT and MST.

27 e unknown, but neurons in brain areas MT and MST may contribute given their sensitivity to motion par

28 to investigate whether cells in areas MT and MST with well-established neurophysiological properties

29 hogonal methods employing EMSA, STD-NMR, and MST methodologies.

30 , and frontomedial electrode placements) and MST (round coil on vertex) in nonhuman primates.

31 on of >/=60% protein needs after surgery and MST scores were independent predictors of LOS.

32 al model of primate visual areas V1, MT, and MSTd based on that of Layton, Mingolla, and Browning tha

33 Anthropometry/BC and MSTs were compared with each other and with clinical out

34 ent between BC/anthropometric parameters and MSTs was poor.

35 the survival using depleting IgG2a antibody (MST=18) was similar to that using WT FR70.

36 ull hypothesis is rejected and second, apply MST-based tests to these pathways to select those that s

37 ies that exceeded those seen in cortex (area MSTd) under identical conditions.

38 on by recording from neurons in macaque area MSTd that integrate visual and vestibular cues regarding

39 pulation activity of neurons in macaque area MSTd.

40 ex [including medial superior temporal area (MST), fundus of superior temporal area (FST), and dorsal

41 (MT), and the medial-superior temporal area (MST).

42 vision of the medial superior temporal area (MSTd) and the ventral intraparietal area (VIP), have bee

43 corded dorsal medial superior temporal area (MSTd) cortical neuronal responses to the visual motion a

44 umans, dorsal medial superior temporal area (MSTd) has been implicated in heading perception.

45 The dorsal medial superior temporal area (MSTd) in the extrastriate visual cortex is thought to pl

46 tuning in the medial superior temporal area (MSTd) is approximately head centered.

47 ement, dorsal medial superior temporal area (MSTd) neurons represent their current heading direction.

48 nd the dorsal medial superior temporal area (MSTd) of macaques.

49 t, unlike the medial superior temporal area (MSTd) where optic flow tuning typically dominates or the

50 gions, dorsal medial superior temporal area (MSTd), ventral intraparietal area (VIP), and visual post

51 ), and dorsal medial superior temporal area (MSTd).

52 ng the dorsal medial superior temporal area (MSTd).

53 Similar to areas MSTd and VIP, the population of V6 neurons was best able

54 However, unlike areas MSTd and VIP, V6 neurons are almost universally unrespon

55 Area V6 is interconnected with areas MSTd and VIP, allowing for the possibility that V6 also

56 can induce seizures with E-field as focal as MST, although these electrode and coil configurations af

57 and those predicted by ideal models such as MST.

58 lamblia were detected in sewage, as well as MST markers and resistance genes to aminoglycosides, bet

59 To overcome these issues, a community-based MST method has been developed.

60 These results suggest that a community-based MST method may be another useful tool for determining so

61 ram can be a useful tool for community-based MST studies.

62 ion, is an emerging tool for community-based MST studies.

63 e a fecal library to perform community-based MST.

64 target populations required for marker-based MST occur around the globe.

65 Clustering cells before MST construction reduces the complexity of the tree spac

66 lly adjusted models, the interaction between MST status and sex was significant in the 30-day and 1-y

67 Our results support a causal link between MSTd neurons and multisensory heading perception but sug

68 de, consistent with the idea that biological MSTd might be well equipped to efficiently encode variou

69 r length-scaling exponents than predicted by MST due to an evolutionary tradeoff between fire escape

70 The kinetics of H2S production by MST from 3-MP was studied at pH 7.4 in the presence of v

71 transsynaptic networks that are targeted by MST for optimal therapeutic response.

72 dicate that sulphide generated by CSE or CAT/MST or from thiosulphate is unlikely to contribute to O2

73 ase/mercaptopyruvate sulphurtransferase (CAT/MST) pathway caused an increase in HPV similar to that o

74 sue growth and homeostasis through a central MST-LATS kinase cascade.

75 lateral ECT (25%) was comparable to cap coil MST (23%), demonstrating that ECT with a low current amp

76 Future studies should compare MST and ECT under double-blind randomized condition.

77 onducted in North London, England, comparing MST with usual services provided by two youth offending

78 Under open conditions, MST led to clinically meaningful reduction in depressive

79 In contrast, MSTd neurons show reference frames between head and eye

80 (MST=18.5 days) and rAAV-K-treated controls (MST=19 days).

81 n-specific phages (detected using a low-cost MST method) in municipal wastewaters (MW) and assesses w

82 The Salvador adaptor protein couples MST kinases to the LATS kinases to form the hippo pathwa

83 d allows identification of the most credible MST or MSTs by using a bootstrapping metric.

84 fter the development of severe renal damage (MST after proteinuria onset was 12.5 weeks versus 4 week

85 om an unplanned change in heading direction, MSTd shifts toward representing the goal location.

86 eed, and disparity tuning of cells in dorsal MST (MSTd) to estimate the combined motion parallax and

87 STN 20 mg/kg nor CsA 20 mg/kg was effective (MST 6 days [n=2] and 7 days [n=5], respectively).

88 versible inhibitor of the telomerase enzyme, MST-312, to investigate telomerase activity during HSV i

89 tion was hampered by variable ratios of FIB, MST markers, and pathogens measured in seawater and in g

90 al predictions from the three models we find MST predictions are most consistent with our observed al

91 nfirmed minimal carryover of mtDNA following MST.

92 ation focality by 40-53% for ECT and 26% for MST, supporting amplitude individualization as a means o

93 major physiological persulfide acceptor for MST.

94 CT and 37.4% of maximum device amplitude for MST).

95 human and a ruminant-specific qPCR assay for MST in a drinking water source.

96 llows us to propose a detailed mechanism for MST in which an Asp-His-Ser catalytic triad is positione

97 Further investigation into the mechanism for MST-312 is warranted and may provide novel targets for H

98 higher among those who screened positive for MST compared with those who screened negative (30-day: a

99 Positive response to screen for MST administered in VHA facilities.

100 A positive screen for MST was independently associated with postdeployment hom

101 A positive screen for MST was significantly and independently associated with

102 Among veterans with a positive screen for MST, rates of homelessness were 1.6% within 30 days, 4.4

103 sness among males with a positive screen for MST.

104 to three times per week with high-frequency MST (i.e., 100 Hz) (N = 24), medium frequency MST (i.e.,

105 .e., 60 or 50 Hz) (N = 26), or low-frequency MST (i.e., 25 Hz MST) (N = 36) using 100% stimulator out

106 ST (i.e., 100 Hz) (N = 24), medium frequency MST (i.e., 60 or 50 Hz) (N = 26), or low-frequency MST (

107 Moreover, our data from MST analysis have pointed to positive binding cooperativ

108 sistent with a mixture of contributions from MSTd and other areas with vestibular-dominant tuning for

109 ted with PIVC, and receives projections from MSTd.

110 Furthermore, MST-312 treatment inhibited virus replication, as measur

111 We devised a Global MST Enrichment (GME) kit to enrich and nextgen sequence

112 genetically with another D. discoideum Hippo/MST homolog, KrsA, but the two genes are not functionall

113 These studies show that Hippo/MST proteins, like the tumor suppressor PTEN and oncogen

114 However, MST revealed correlations between FIB and gull source tr

115 expressed, purified, and crystallized human MST in the presence of the substrate 3-mercaptopyruvate

116 In human MST and putative VIP, multivoxel pattern analysis permit

117 (N = 26), or low-frequency MST (i.e., 25 Hz MST) (N = 36) using 100% stimulator output.

118 High-frequency (100 Hz) MST produced the highest remission rate (33.3%).

119 l)]tris(2,4,6-trimethylbenzenesulfonam ido, [MST](3-).

120 to prepare the Co(II)/Ca(II) complex [Co(II)MST(mu-OH(2))Ca(II) subset15-crown-5(OH(2))](+) ([Co(II)

121 I)MST](-) to form the five-coordinate [Co(II)MST(OH(2))](-) complex that was used to prepare the Co(I

122 [Co(II)MST(OH(2))](-) was oxidized to form [Co(III)MST(OH(2))]

123 Water binds to [Co(II)MST](-) to form the five-coordinate [Co(II)MST(OH(2))](-

124 lso synthesized from the oxidation of [Co(II)MST](-) with iodosylbenzene (PhIO) in the presence of Ca

125 H(2))] that was further converted to [Co(III)MST(mu-OH)Ca(II) subset15-crown-5](+) ([Co(III)(mu-OH)Ca

126 )MST(OH(2))](-) was oxidized to form [Co(III)MST(OH(2))] that was further converted to [Co(III)MST(mu

127 In MST analysis, children with ASD showed a significant low

128 gions; 25%-30% of cells in MT and 40%-60% in MST are pattern direction selective.

129 examined in relation to overnight changes in MST performance.

130 erged from recurrent feedback connections in MST and allowed the model to better suppress the appropr

131 gional applicability of enterococci hosts in MST application and highlights the significance of multi

132 ST was more variable in ECT than in MST.

133 long complex trajectories, and that cells in MSTd are specifically tuned to extract complex trajector

134 um of observed cells (radial to circular) in MSTd can simultaneously code curvature and heading acros

135 MSTd based on the hypothesis that neurons in MSTd efficiently encode the continuum of large-field ret

136 fact that vestibular heading preferences in MSTd are more weakly clustered than visual preferences a

137 representation of visual heading signals in MSTd, but contrasts sharply with the body-centered repre

138 head position gain fields were strongest in MSTd and weakest in PIVC.

139 However, tuning in MSTd neurons primarily reflects sensory inputs, whereas

140 Here we measured heading tuning in MSTd using a novel stimulus paradigm, in which we stabil

141 resentation, unlike visual heading tuning in MSTd, which is approximately eye centered.

142 in VPS, intermediate in VIP, and weakest in MSTd.

143 ta demonstrate that the telomerase inhibitor MST-312 suppressed HSV replication at multiple steps of

144 ter large bilateral muscimol injections into MSTd.

145 s of STN (7 or 2 mg/kg) with CsA (20 mg/kg), MST was more than 100 (n=3) and 22 days (n=2), respectiv

146 of the upstream mammalian STE20-like kinase (MST) proteins.

147 Among our six implementations, KScons MST-MP (which uses the multiple structure alignment prio

148 Over the CASP10 and CASP11 sets, KScons MST-MP performs better than the leading methods using on

149 is of recall and precision finds that KScons MST-MP improves accuracy not only by improving identific

150 e often contradictory findings about macaque MSTd, and offers a biologically plausible account of a w

151 we describe a computational model of macaque MSTd based on the hypothesis that neurons in MSTd effici

152 The mammalian MST kinase family, which is related to the Hippo kinase

153 We show that many MSTd neurons exhibit the diagnostic form of cross-modal

154 The model (1) relies on two mechanisms (MST-MT feedback and disinhibition of opponent motion sig

155 ated rejection in primed, uninoculated mice (MST=12 days).

156 known repeat regions called microsatellites (MST).

157 includes recurrent interactions among model MSTd neurons.

158 At the population level, model MSTd accurately predicts eye velocity and heading using

159 and disparity tuning of cells in dorsal MST (MSTd) to estimate the combined motion parallax and dispa

160 th neuronal recordings from macaque areas MT/MST.

161 the Hippo pathway in cells lacking multiple MST kinases.

162 Moreover, the presence of 20 muM to 100 muM MST-312 during infection led to a 2.5- to 5.5-log10 decr

163 double the rates of veterans with a negative MST screen (0.7%, 1.8%, and 4.3%, respectively).

164 detects in evaluating the performance of new MST host strains.

165 0 days; P = 0.03), and from BALB/c into NOD (MST: 12.0 vs. 5.5 days; P = 0.003).

166 .0 days; P = 0.004), from NOD.SCID into NOD (MST: 23.5 vs. 14.0 days; P = 0.03), and from BALB/c into

167 ed before initiation and after completion of MST using the Scale for Suicide Ideation (SSI).

168 After completion of MST, patients had a mean SSI score of 4.2 (6.3) (pre-pos

169 The contribution of MST versus the other two H2S generators, cystathionine b

170 6), but more expensive including the cost of MST, although not significantly so ( pound5,687 versus p

171 n of suicidal ideation following a course of MST.

172 nd were deemed to have an adequate course of MST; and 47 completed the trial per protocol, either ach

173 A cost-offset evaluation of MST based on data from a randomised controlled trial con

174 essed within 1 week before the initiation of MST treatment using the TMS-EEG measures of cortical inh

175 ling approach improves the interpretation of MST data, especially when fecal pollution from the same

176 ed to evaluate and verify the performance of MST assays and, therefore, to identify important sources

177 Sensitivity (percentage true positives) of MST results in sewage and animal waste samples (21-33%)

178 he KOS1.1 strain of HSV-1 in the presence of MST-312.

179 nt in the RASSF pathway is the regulation of MST kinases, which are main effectors of RASSF-induced a

180 used it to probe the complex selectivity of MST neurons.

181 The crystal structure of MST reveals a mixture of the product complex containing

182 In support of MST, after fire, forest structure appears to approximate

183 were part of an open-label clinical trial of MST treatment.

184 selectivity, might simply be a byproduct of MSTd neurons performing dimensionality reduction on thei

185 se properties might simply be a byproduct of MSTd neurons performing dimensionality reduction on thei

186 gnals on the preferred heading directions of MSTd neurons.

187 del challenges the view that the function of MSTd is heading estimation, based on our analysis we cla

188 However, the majority of MSTd neurons respond optimally to spiral patterns, rathe

189 te neurophysiological response properties of MSTd cells, such as 3D translation and rotation selectiv

190 he often nonintuitive response properties of MSTd neurons; (2) suggest that response properties, such

191 By measuring responses of MSTd neurons in two male rhesus monkeys and by applying

192 ifficult to evaluate because many studies on MST have been conducted at high pH and have used varied

193 lses delivered through the ECT electrodes or MST coil.

194 s identification of the most credible MST or MSTs by using a bootstrapping metric.

195 Overall, MST data enabled management action despite an inability

196 ctivation techniques to artificially perturb MSTd activity while monitoring behavioral performance.

197 Each unit increase in preoperative MST score predicted longer LOSs of 2.5 d (95% CI: 1.5, 3

198 ver, STN 20 mg/kg and CsA 20 mg/kg prolonged MST to more than 100 days (n=5).

199 ged in mice treated with the early protocol (MST = 48 days), but most were rejected by d100.

200 standardized data analysis protocol for qPCR MST assays for interlaboratory consistency and comparabi

201 ed assays appear to be suitable quantitative MST tools beyond the regional level while the targeted h

202 utive patients with MDD consented to receive MST applied over the prefrontal cortex according to an o

203 grammed PAK4 mutant, engineered to recognize MST substrates, failed to phosphorylate PAK4 substrates

204 n factor to compensate the partially relaxed MST experiments, thus allowing measurement of enzyme kin

205 top-down spatial location signals, reshaping MSTd's response properties through task-dependent intera

206 ing IgG1 antibody was significantly shorter (MST=14 days), whereas the survival using depleting IgG2a

207 tralian estuarine isolate of Penicillium sp. MST-MF667 yielded 3 tetrapeptides named the bilaids with

208 Mercaptopyruvate sulfurtransferase (MST) is a source of endogenous H2S, a gaseous signaling

209 py only marginally prolonged graft survival (MST = 13.16 d; group 2) compared with untreated controls

210 d on the finger-tapping motor sequence task (MST) at bedtime and tested the following morning.

211 hy with training on the Motor Sequence Task (MST) on the second night and testing the following morni

212 7, we designed the Mnemonic Similarity Task (MST), a modified object recognition memory task, to be h

213 Neurons in the medial superior temporal (MST) area of the primate visual cortex respond selective

214 (MT) area and the medial superior temporal (MST) area: two neighboring extrastriate cortical areas o

215 temporal (MT) and medial superior temporal (MST) areas.

216 ed from the dorsal medial superior temporal (MSTd) and ventral intraparietal (VIP) areas of monkeys d

217 rved in the dorsal medial superior temporal (MSTd) and ventral intraparietal areas.

218 l subregion of the medial superior temporal (MSTd) area of the macaque respond to large, complex patt

219 that a variety of medial superior temporal (MSTd) neural response properties could be derived from M

220 ed secondary K skin grafts in the long term (MST>100 days) compared to accelerated rejection in prime

221 simulated and for gene expression data that MST-based tests discriminate well against shift and scal

222 Together, these findings demonstrate that MST-312 interferes with the HSV life cycle.

223 In our simulation study, we demonstrate that MST-based tests have power that is for many settings com

224 Additionally, we determined that MST-312 has the largest impact on viral events that take

225 orted in this study support the finding that MST+YOT has scope for cost-savings when compared to YOT

226 Recent research suggests that MST may be a determinant in several factors associated w

227 We conclude that MSTd responses are not rigidly linked to specific stimul

228 However, ample evidence suggests that MSTd neurons exhibit a continuum of visual response sele

229 The MST enzymes (menaquinone, siderophore, and tryptophan bi

230 The MST is now a widely used behavioral task, repeatedly sho

231 The MST treatments were administered under general anesthesi

232 The MST+YOT group were significantly cheaper in terms of YOT

233 The MST-LATS kinase cascade is central to the Hippo pathway

234 assessed whether low protein intakes and the MST score were predictive of LOS.Total protein intakes w

235 merase and lyase activities performed by the MST enzymes are functionally conserved.

236 ident in both groups, but were higher in the MST+YOT group.

237 chemical data proved the plausibility of the MST findings.

238 ese results underscore the importance of the MST screen as a clinically important marker of reintegra

239 tes the high efficiency and potential of the MST technique, not only to prevent the transmission of m

240 Here, we review the utility of the MST, its relationship to hippocampal function, its utili

241 failed to show overnight improvement on the MST and differed significantly from control participants

242 predicted less overnight improvement on the MST.

243 At 18-month follow-up, the MST+YOT group cost less in terms of criminal activity (

244 MT that locally match the preference of the MSTd cell in both parallax and disparity.

245 rmed intramolecular hydrogen bonds with the [MST](3-) ligand.

246 Metabolic scaling theory (MST) posits that the scaling exponents among plant heigh

247 potheses regarding metabolic scaling theory (MST), C recovery and biodiversity.

248 nt scaling models (Metabolic Scaling Theory (MST), Geometric Similarity, and Stress Similarity) in sa

249 Magnetic seizure therapy (MST) induces a weaker and more focal electric field than

250 Magnetic seizure therapy (MST) is a novel therapeutic option for treatment-resista

251 Magnetic seizure therapy (MST) is a potential alternative to ECT that may not adve

252 frontomedial) and magnetic seizure therapy (MST) with cap coil on vertex.

253 seizures, as with magnetic seizure therapy (MST), or modifications to ECT.

254 Microscale thermophoresis (MST) binding studies validate the NMR results and identi

255 demonstrate that microscale thermophoresis (MST) is a valuable method for screening for ligands and

256 oring (QCM-D) and microscale thermophoresis (MST) we have been able to determine DHFR-TS binding kine

257 alorimetry (ITC), Microscale Thermophoresis (MST), and Electrophoretic Mobility Shift Assay (EMSA).

258 resonance (SPR), microscale thermophoresis (MST), and theoretical models for determining the thermod

259 proximately 11:30 PM Mountain Standard Time (MST) on Friday, February 14, 2014.

260 grafts with increased median survival time (MST) more than 169 days compared to uninoculated (MST=18

261 nanogels increased the median survival time (MST) of lupus-prone NZB/W F1 mice by 3 months with proph

262 mg/kg twice daily, the median survival time (MST) was 27 days (n=4).

263 cceptance: the BMT/renal mean survival time (MST, 76 days) was not significantly different than the r

264 rom BALB/c into C57BL/6 (mean survival time [MST]: 16.5 vs. 12.0 days; P = 0.004), from NOD.SCID into

265 d with untreated mice (median survival time [MST]=10 days).

266 aged 11-17 years, were randomly allocated to MST+YOT (n = 56) or YOT alone (n = 52).

267 We instead propose a systematic approach to MST estimation that bases analyses on the optimal comput

268 vertheless, there are significant caveats to MST algorithms that have been largely ignored in molecul

269 By comparison to MSTd, VIP contains fewer disparity-selective neurons (41

270 ed preoperative Malnutrition Screening Tool (MST) score, 3-d food records, postoperative nausea, LOS,

271 ition (BC) and malnutrition screening tools (MSTs) for detecting malnutrition on admission; and exami

272 The microbial source tracking (MST) approach presented here provides a framework for fu

273 tigation included microbial source tracking (MST) for human, gull, and canine fecal sources, monitori

274 assays for microbial fecal source tracking (MST) have been developed and evaluated in recent years.

275 oped and used for microbial source tracking (MST) in environmental waters.

276 teria, protozoa), microbial source tracking (MST) markers, and antibiotic resistance genes was tested

277 These microbial source tracking (MST) methods are powerful tools to manage water quality

278 entation of microbial fecal source tracking (MST) methods in drinking water management is limited by

279 FIB) and emerging microbial source tracking (MST) methods may indicate the presence and even the like

280 s are employed in microbial source tracking (MST) studies globally, however little is known regarding

281 The widely used microbial source tracking (MST) technique, quantitative polymerase chain reaction (

282 ation provided by microbial source tracking (MST) to map hot spots (i.e., likely sources) of fecal co

283 d sewage-specific microbial source tracking (MST) tools using enterococci bacteriophages and evaluate

284 Community-based microbial source tracking (MST) utilizes high-throughput DNA sequencing to profile

285 Quantitative Microbial Source Tracking (MST) was employed from 2012 to 2015 to inventory sources

286 Current microbial source-tracking (MST) methods, employed to determine sources of fecal con

287 he utility of the maternal spindle transfer (MST) technique as a reproductive approach to enhance ooc

288 Gs) and undergo mitotic somal translocation (MST) during division.

289 ivision, termed mitotic somal translocation (MST).

290 Military sexual trauma (MST) is associated with adverse physical and mental heal

291 uses a cluster-based minimum spanning tree (MST) approach to order cells.

292 Type I error rates of minimum-spanning tree (MST)-based non-parametric multivariate tests with severa

293 ary graph, as well as minimum spanning tree (MST).

294 cation by the micellar selectivity triangle (MST).

295 ping (MLST) and multispacer sequence typing (MST).

296 more than 169 days compared to uninoculated (MST=18.5 days) and rAAV-K-treated controls (MST=19 days)

297 , it can pave a way for future simple-to-use MST screening tools.

298 W F1 mice by 3 months with prophylactic use (MST was 50 weeks versus 38 weeks without treatment), and

299 model, islet survival was prolonged as well (MST: muMT = 32.5 vs. WT = 14 days; P = 0.002).

300 ons where observations are inconsistent with MST we find that departure from theory corresponds with