ライフサイエンスコーパス: MT

1 MT expression was measured using quantitative real-time

2 MT images of the cervical spinal cord were collected par

3 MT imaging identified tract specific and regional change

4 MT levels in CP+S group were significantly raised in com

5 MT use for FN increased the surgical yield of cancer by

6 MT was assessed prior to implant placement and 1, 6, and

7 MT- 27%; P < 0.001) and more likely for histologic TC (7

8 MT-4 cells express higher levels of plasma-membrane-asso

9 MT-SCCALR learns genotype-phenotype associations of mult

10 T to yield cooperative products, i.e., Ag(4)-MT and Cd(4)-MT, these products are very different; Ag(+

11 g revealed that all four Ag(+) ions of Ag(4)-MT are bound to the beta-domain.

12 ucts are very different; Ag(+) ions of Ag(4)-MT are located in the beta-domain, whereas Cd(2+) ions o

13 The results for Ag(4)-MT are then compared to similar results obtained for Cd(

14 The results show that Ag(4)-MT is a cooperative product, and data from top-down and

15 metalated forms of human MT-2A, viz., Ag(4)-MT.

16 he beta-domain, whereas Cd(2+) ions of Cd(4)-MT are located in the alpha-domain.

17 operative products, i.e., Ag(4)-MT and Cd(4)-MT, these products are very different; Ag(+) ions of Ag(

18 mpared to similar results obtained for Cd(4)-MT.

19 d selectivity to NTMT1/2 among a panel of 41 MTs, indicating its potential to achieve high selectivit

20 Ag(6)-MT has been reported to be fully metalated in the beta-d

21 al, and biogenetical approaches to analyze a MT-CYB-deficient human cell line.

22 barriers provided additional evidence for a MT-based pushing mechanism.

23 se free Gbetagamma also activates hSlo1 in a MT(1)-dependent and membrane-delimited manner, whereas a

24 tified, precisely how gamma-TuRC nucleates a MT remains poorly understood.

25 in affinity, which facilitates assembly of a MT from gamma-TuRC.

26 assay to directly visualize nucleation of a MT from purified Xenopus laevis gamma-TuRC.

27 le number and the accumulation of acetylated MTs.

28 glycylation leads to faster diffusion across MT protofilaments.

29 s pinpoint NAV1 as a key player in the actin-MT crosstalk that promotes MT persistence at the GC peri

30 rosomal recruitment of EB1 without affecting MT growth rate.

31 al oxygenation, eGFR, and SCr improved after MT + PTRA.

32 e more likely to exhibit poor outcomes after MT, particularly when recanalization fails.

33 logical inhibition of HDAC6 protects against MT disorganization and reduces the size of acetylcholine

34 , and medullary TC were positive whereas all MT- malignancies were low-risk.

35 tails lead to slower protein diffusion along MTs, although polyglycylation leads to faster diffusion

36 lecular mechanism of protein diffusion along MTs.

37 lecular mechanism of protein diffusion along MTs.

38 These results predict that altering MT network structure in beta cells can be used to tune G

39 eparate during the disassembly process of an MT.

40 k motor that moves slowly and diffuses on an MT.

41 Melatonin receptors MT(1) and MT(2) are involved in synchronizing circadian rhythms an

42 f two G-protein-coupled receptors: MT(1) and MT(2).

43 metry to the final organization of actin and MT cytoskeletons in single plant cells of Arabidopsis th

44 Spiking activity in koniocellular cells and MT cells shows substantial correlation to the local popu

45 Demographic and MT characteristics were assessed and compared between SP

46 howed increased microtubule (MT) density and MT assembly was key to sustaining stretch-growth, sugges

47 solically relevant concentrations of GSH and MT.

48 s of ATP7A and the metallothioneins MT-I and MT-II to cell viability under conditions of Cu excess or

49 ow differential neuronal coupling of LGN and MT cells to local population spiking activity.

50 pike rate and population coupling in LGN and MT, and establishes a unified account of dynamic spiking

51 fluctuations of spiking activity in LGN and MT.

52 n occurring at an input stage fed to MT, and MT neurons cannot overturn this bias based on their own

53 patiotemporal evolution of MTOC position and MT cytoskeleton morphology with experimental observation

54 AVR costs decreased over time while SAVR and MT costs remained unchanged.

55 In visual areas V1 and MT, some directionally selective cells are also tuned fo

56 percutaneous transluminal renal angioplasty (MT + PTRA) (n = 11, 3 bilaterally, n = 14 kidneys) or MT

57 nt koniocellular (K) pathway in LGN and area MT exhibits strong fractal fluctuations at short (<1 s)

58 in the ventral visual pathway, just as area MT is the first motion-specific processing stage in the

59 ng memory-guided direction comparisons, area MT and the prefrontal cortex, revealing their likely int

60 geniculate nucleus, LGN) and cortical (area MT) visual areas in anaesthetised marmosets.

61 l geniculate nucleus (LGN) and cortical area MT, in marmoset monkeys.

62 ncient koniocellular LGN pathway and in area MT show high-amplitude fractal fluctuations, whereas evo

63 local field potentials (LFP) in visual area MT of macaque monkeys.

64 ion processing region [middle temporal area (MT+)] and its primary input region (V1).

65 he higher order middle temporal visual area (MT), which appears to be histologically distinct near th

66 Arterial %MT and %IT of nonobstructed lung territories and venous

67 onset of mitosis, the position of the astral MT network, specifically its center, determines the even

68 Ts that form interpolar bundles or by astral MTs connected to the cell cortex.

69 st chemotypes with sub-micromolar potency at MT receptors, with compound 21 reaching EC(50) of 0.36 n

70 dramatically reduced arrestin recruitment at MT(2), while compound 37 was devoid of G(i) signaling at

71 compound 37 was devoid of G(i) signaling at MT(1), implying biased signaling.

72 t-stop (Shot) promotes the crosstalk between MTs and actin, which leads to the extension and guidance

73 NAV1 can also bind MTs independently of EB1 in vitro and crosslinks nonpoly

74 terminal domain in CLASP2 that promotes both MT stabilization and early infection.

75 ution 3D crystal structures of agonist-bound MT receptors.

76 ntial cellular phenomenon termed 'branching' MT nucleation.

77 binding and transport of insulin granules by MT motors prevents their stable anchoring to the PM.

78 Consecutive patients treated by MT in four high volume centers between January 2014 and

79 Of 906 patients treated by MT, 576 (64%) were handled on a BP system.

80 hibits Katanin ATPase activity stimulated by MTs.

81 r a comprehensive understanding of hair cell MT at molecular and atomic levels.

82 s, we propose a unifying theory of hair cell MT that may reconcile most of the functional discoveries

83 being important for the formation of central MT pairs, proper orientation of basal bodies, and synchr

84 Importantly, the central MT pairs were missing in the majority of cilia, and the

85 the Cep63-Cep152 assembly around centriolar MTs and promoting centriole biogenesis.

86 depletion of Arl4D resulted in a centrosomal MT nucleation defect.

87 tches as well as a short segment of a closed MT in both GTP- and GDP-bound states.

88 an motion-sensitive middle temporal complex (MT+) and temporo-parietal junction (TPJ).

89 LIS1 acts as a key molecular link connecting MTs/dynein and actomyosin, ensuring that cell membrane c

90 A conserved MT-associated protein complex, Augmin, recruits gamma-Tu

91 e how neurons in the middle temporal cortex (MT) represent multiple stimuli that compete in more than

92 in 2 (CLASP2), a +TIP that captures cortical MT plus ends to enable filament stabilization, as a host

93 t abolishing Arl4D-EB1 interaction decreased MT nucleation rate and diminished the centrosomal recrui

94 , but their collective function in the dense MT cytoskeleton of neurites remains elusive.

95 r segregation coincides with DREPP-dependent MT fragmentation and a partial loss of the ability to re

96 MPhi depletion, MT disruption, targeted kinase inhibition, and altered M

97 otein amount of acetylated and detyrosinated MT.

98 lation results in a decline of detyrosinated MTs in an MI model.

99 ould be observed, leading to three different MT based phenotypes.

100 date however, the function(s) of the dynamic MT network and its relative stability in the formation a

101 to a "macroscopic" Fe(2)O(3) based exemplar MT system, unconfined compressive strengths of 5171 and

102 was 2.0 for SAVR, 3.0 for TAVR, and 4.3 for MT; the average number of total admissions was 1.3 for S

103 was 1.3 for SAVR, 1.5 for TAVR, and 1.7 for MT (P<0.01 for all).

104 dynactin and the EB1, which is important for MT stabilization.

105 mics simulations (1 mus for each system) for MT patches as well as a short segment of a closed MT in

106 otube formation and Tkv internalization from MT-nanotubes into hub cells both resulted in an overabun

107 orporated into virus particles produced from MT-4 than SupT1 cells.

108 (ST), eyes with medically treated glaucoma (MT), and eyes without glaucoma (NG).

109 tate tubulin dimer is exposed at the growing MT end, these factors will be more likely to cause the M

110 It has been proposed that the growing MT ends are protected by a "GTP cap" that consists of GT

111 ets are generally not stable against the GSH/MT system, which creates a challenge for their future de

112 ronger activations of middle temporal gyrus (MT/V5), and hippocampus were found in the aesthetic judg

113 individuals with ASD: individuals with high MT+ responses had attenuated V1 responses.

114 cantly and positively associated with higher MT in the bilateral frontal and parietal lobes.

115 to clarify the long-standing question of how MT-4 cells overcome the requirement for the HIV-1 gp41 C

116 We show how MT enzymes can utilise cxSAM to catalyse carboxymethylat

117 The molecular details of how MTs distinguish MAChRs are not well understood.

118 In cells, however, MTs are exposed to various biomechanical forces that mig

119 es of the partially metalated forms of human MT-2A, viz., Ag(4)-MT.

120 Results from CIU suggest that Ag(i)-MT complexes are structurally more ordered and that the

121 We investigate if MT use for FN directs appropriate thyroidectomy for TC w

122 cytolysis and was accompanied by changes in MT dynamics as measured by phosphorylation status of sta

123 S signalling in disease including changes in MT network density and post-translational modifications

124 s no statistically significant difference in MT levels among CP+NS and PH+S groups (P > 0.05); howeve

125 gesting a possible role of tensile forces in MT translocation/assembly.

126 [ADM]) resulted in a significant increase in MT compared to non-augmented sites.

127 subpopulations suppresses motion signals in MT that locally match the preference of the MSTd cell in

128 els of Ca(2+) signalling in heart to include MT-dependent mechanotransduction through X-ROS.

129 Compounds known to induce MT release like progesterone, ZnSO(4), quercetin, dexame

130 s a host factor that enables HIV-1 to induce MT stabilization and promote early infection in natural

131 CLASP2 C-terminal mutant is unable to induce MT stabilization or promote early HIV-1 infection.

132 domly assigned to a mindfulness instruction (MT) group or an instructed thinking (IT) group.

133 orces are supplied either by interdigitating MTs that form interpolar bundles or by astral MTs connec

134 es a random meshwork in the cells' interior, MTs near the cell surface are preferentially aligned wit

135 In Caenorhabditis elegans, Katanin MT-severing activity is essential for meiotic spindle as

136 this impaired the correction of erroneous KT-MT attachments, it did not compromise the mitotic checkp

137 correct improper kinetochore-microtubule (KT-MT) attachments, whereas tension across the centromeres

138 and orchestrate the L(RdRP), L(PRNT), and L(MT), an oligomeric phosphoprotein (P) is required.

139 pedance spectroscopy studies observed that L-MT sample performed low charge transfer resistance (336.

140 e transport of cargo by motor proteins, many MT-binding proteins seem to adopt diffusional motility a

141 Meanwhile, MT-SCCALR cannot only select relevant SNPs and imaging Q

142 Percent media (%MT; arteries) and intima thickness (%IT; arteries, veins

143 Metallothionein (MT), a cysteine rich protein is involved as a radical sc

144 tributions of ATP7A and the metallothioneins MT-I and MT-II to cell viability under conditions of Cu

145 se 5 (PRMT5) is the major methyltransferase (MT) catalyzing symmetric dimethylation (SDM).

146 thionine (SAM)-dependent methyltransferases (MTs) catalyse the methylation of a vast array of small m

147 Microtubule (MT) mechanotransduction links diastolic stretch to gener

148 Microtubule (MT) plus-end tracking proteins (+TIPs) are central playe

149 Intriguingly, Cep63 fused to a microtubule (MT)-binding domain of Cep57 functioned in concert with C

150 orces to separate post-anaphase microtubule (MT) asters in Xenopus laevis and other large eggs remain

151 The evolutionarily conserved microtubule (MT)-severing AAA-ATPase enzyme Katanin is emerging as a

152 ing axon growth by facilitating microtubule (MT) polymerization.

153 tretched axons showed increased microtubule (MT) density and MT assembly was key to sustaining stretc

154 importance of kinetochore (KT)-microtubule (MT) attachment has been known for many years, increasing

155 In addition, formation of microtubule (MT) arrays was necessary for cytolysis and was accompani

156 The orientation of microtubule (MT) networks is exploited by motors to deliver cargoes t

157 ownregulating the expression of microtubule (MT) plus-end tracking protein (+TIP) called EB1 (end-bin

158 migration via dysregulation of microtubule (MT) stability and dynein motor function/localization tha

159 d adhesion via their effects on microtubule (MT) and F-actin cytoskeletal organization across the epi

160 xploits a number of specialized microtubule (MT) plus-end tracking proteins (commonly known as +TIPs)

161 Here, we demonstrate that microtubule (MT)-motor-mediated transport dynamics have a critical ro

162 the eukaryotic cell cycle, the microtubule (MT) cytoskeleton serves as both a supportive scaffold fo

163 le is sufficient to explain the microtubule (MT) organization observed in cells.

164 The microtubule (MT)-depolymerizing activity of MCAK/Kif2C can be quantif

165 Microtubules (MTs) are known to be post-translationally modified at th

166 Microtubules (MTs) mediate mitosis, directional signaling, and are the

167 Microtubules (MTs), cylindrical protein polymers composed of tubulin d

168 as a coordinator of actin and microtubules (MTs), powering axonal growth and regeneration.

169 Determining how microtubules (MTs) are nucleated is essential for understanding how th

170 understanding the behavior of microtubules (MTs) and other cytoskeletal polymers.

171 rgoes towards the minus end of microtubules (MTs).

172 stabilization.IMPORTANCE While microtubules (MTs) have long been known to be important for delivery o

173 ce length of the order of a few millimeters, MTs are rigid over cellular dimensions and are thus expe

174 r, our results indicate that Arl4D modulates MT nucleation through regulation of the EB1-p150 associa

175 a new joint multitask learning method, named MT-SCCALR, which absorbs the merits of both SCCA and log

176 that GSCs form microtubule-based nanotubes (MT-nanotubes) that project into the hub cells, serving a

177 EB1 in vitro and crosslinks nonpolymerizing MT plus ends to actin filaments in axonal GCs, preventin

178 e presence of the Mel receptor MT(1) but not MT(2) A peptide acting to release free Gbetagamma also a

179 y safe nonoperative surveillance for >80% of MT-negative patients.

180 lecular framework regulating the behavior of MT filaments.

181 T truncation mutant to spread in cultures of MT-4 cells.

182 ing early, and that the early development of MT may influence the subsequent development of dorsal st

183 on the negative exponential distribution of MT lengths in dynamically unstable populations of tubuli

184 immunohistochemically protein expression of MT-I/II reflect MT2A gene expression levels.

185 nd gingival crevicular fluid (GCF) levels of MT in smokers (S) and non-smokers (NS) with chronic peri

186 nt assay was used to determine the levels of MT in the samples.

187 Perturbation of MT-nanotube formation and Tkv internalization from MT-na

188 tanin is emerging as a critical regulator of MT dynamics.

189 ite the high levels of Env on the surface of MT-4 cells, 2-fold less Env is incorporated into virus p

190 ssed by GSCs and localizes to the surface of MT-nanotubes, where it receives the hub-derived ligand D

191 t smoking and CP can induce the synthesis of MT owing to increased oxidative stress and heavy metals

192 onship between speed and direction tuning of MT neurons.

193 ity to low Cu concentrations, the absence of MTs did not significantly affect Cu tolerance.

194 e role of centrioles and the accumulation of MTs on the protrusive behavior required during the initi

195 Analogous arrangements of MTs have been seen in even bigger spindles, such as meta

196 bout interactions among different classes of MTs in metaphase spindles from Chlamydomonas rheinhardti

197 show that posttranslational modifications of MTs have differing effects on cardiomyocyte YM: Acetylat

198 extracts and observed outward co-movement of MTs, endoplasmic reticulum (ER), mitochondria, acidic or

199 pothesized that both the polarity pattern of MTs along the neurite shaft and the shaft's global exten

200 as a new approach to analyze the polarity of MTs in the Drosophila oocyte, a cell that displays disti

201 tor of cortical capture and stabilization of MTs, interacts with incoming HIV-1 particles, and we ide

202 er for diffusion is larger when diffusion on MTs is mediated primarily by the MT tails rather than th

203 an intrinsically disordered protein (Tau) on MTs.

204 SAVR (10.0 days) than for TAVR (7.0 day) or MT (5.3 days), but the average number of unplanned readm

205 ) (n = 11, 3 bilaterally, n = 14 kidneys) or MT (n = 9).

206 2 004 742 US registry donors have the TT or MT genotype.

207 ed mutagenesis was used to create orthogonal MTs possessing improved catalytic activity and selectivi

208 When two stimuli were overlapping, MT responses were dominated by the stimulus component th

209 es revenue of $1488 per hectare (at $121 per MT), which is significantly lower than the organic corn

210 ganic corn at $2793 per hectare (at $294 per MT).

211 With preoperative MT, all American Thyroid Association intermediate, high-

212 to actin filaments in axonal GCs, preventing MT depolymerization in F-actin-rich areas.

213 ayer in the actin-MT crosstalk that promotes MT persistence at the GC periphery and regulates GC stee

214 acking and intravital microscopy to quantify MT dynamics in live xenograft tumor models.

215 ng SAVR or TAVR were classified as receiving MT.

216 d manner in the presence of the Mel receptor MT(1) but not MT(2) A peptide acting to release free Gbe

217 Melatonin receptors MT(1) and MT(2) are involved in synchronizing circadian

218 actions of two G-protein-coupled receptors: MT(1) and MT(2).

219 polarization via IL10R blockade all reduced MT coherence and/or tumor cell elongation.

220 on of fMRI response magnitude between region MT+ and V1 in individuals with ASD: individuals with hig

221 enial complex) or a motion-selective region (MT).

222 ture-based optimization led to two selective MT(1) inverse agonists-which were topologically unrelate

223 temporal signature similar to that of single MT neurons.

224 ransmembrane channel-like 1 is a long-sought MT channel subunit.

225 evealed the importance of highly specialized MT regulators that belong to a family called plus-end tr

226 strategy for diabetes by targeting specific MT regulators.

227 recruits gamma-TuRC to pre-existing spindle MTs, amplifying their number, in an essential cellular p

228 rt or engaging peripheral actin to stabilize MTs, suggesting several family members have the potentia

229 rt with Cep152 to assemble around stabilized MTs in vitro Thus, Cep57 plays a key role in architectin

230 First, this structured MT network preferentially withdraws granules from the PM

231 eir similar primary and tertiary structures, MTs show distinct binding selectivity toward different M

232 chanical thrombectomy (MT) and B) successful MT.

233 d on neurophysiology of the middle temporal (MT) and medial superior temporal (MST) areas.

234 nsemble recordings from the middle temporal (MT) area during perceptual-decision-making, we extracted

235 R and were significantly more expensive than MT alone.

236 We conclude that MT resembles a primary sensory area by developing early,

237 Together, our results demonstrate that MT-nanotubes play dual roles to ensure the short-range n

238 e histological results support the view that MT is functional at or near the time of birth, as is pri

239 experimental support for the assertion that MTs under specific circumstances behave consistently wit

240 It has been hypothesized that MTs also possess intrinsic capacitive and inductive prop

241 e to extreme Cu sensitivity, indicating that MTs are critical for Cu tolerance only in the absence of

242 The MT gene- and protein expression of the MPM-cell lines MS

243 rely on an interaction between DREPP and the MT-organizing protein SPIRAL2.

244 tral players in the coordination between the MT and actin cytoskeletons in growth cones (GCs) during

245 nderstanding of the relationship between the MT and CVD risk.

246 iffusion on MTs is mediated primarily by the MT tails rather than the MT body.

247 ese factors will be more likely to cause the MT to undergo rapid disassembly.

248 % from the RYGB group and 2% and 0% from the MT group achieved BP less than 140/90 mm Hg and less tha

249 ]), 88% from the RYGB group and 80% from the MT group completed follow-up.

250 ptor is internalized into hub cells from the MT-nanotube surface and subsequently degraded in the hub

251 hest in the ST group compared to that in the MT and NG groups (63.8% vs 47.6% vs 44.0%, respectively;

252 Participants in the MT group showed lower activity in the cognitive control

253 Additionally, oxygenated hemoglobin in the MT group tended to be lower than in the IT group.

254 Participants in the MT group were trained to either focus their attention mi

255 the agonist-bound orthosteric pocket in the MT receptor structures for the structure-based discovery

256 s required for HIV-1 replication, but in the MT-4 T-cell line the gp41 CT is not required for a sprea

257 ment, the loss of this GTP cap will lead the MT to undergo rapid disassembly.

258 rmined primarily by correctly localising the MT nucleator, gamma-Tubulin Ring Complex (gamma-TuRC), w

259 overed several molecular constituents of the MT complex, and intense debate has surrounded the molecu

260 ew specific roles of other components of the MT complex, including protocadherin 15, cadherin 23, lip

261 for the molecular-motor-driven motion of the MT cytoskeleton confined between plasma membrane and nuc

262 the experimentally observed features of the MT cytoskeleton dynamics.

263 Stabilization of the MT is dependent in part on its acetylation status, and H

264 o-date synthesis of the existing data on the MT and how it relates to CVD.

265 gulated by the mechanical load acting on the MT array as a whole.

266 receptor after engaging in signaling on the MT-nanotubes has been unclear.

267 ns, and measures of vascular health over the MT, which can increase a woman's risk of developing CVD

268 artial loss of the ability to reorganize the MT cytoskeleton in response to rhizobia, which might rel

269 These findings suggest the MT cytoskeleton may negatively regulate GSIS by both lim

270 ed primarily by the MT tails rather than the MT body.

271 of a downstream signal, suggesting that the MT-nanotubes also serve a second purpose to dampen the n

272 er-resolution imaging shows that whereas the MT cytoskeleton resembles a random meshwork in the cells

273 While the MT nucleator, gamma-tubulin ring complex (gamma-TuRC) ha

274 uster facilitates their interaction with the MTs.

275 patients were treated with medical therapy (MT) and percutaneous transluminal renal angioplasty (MT

276 ll content (SPAD), membrane thermostability (MT), rate of senescence (RS), stay green trait (SGT), an

277 ee-dimensional changes in mucosal thickness (MT) 1 year after treatment with an acellular dermal matr

278 nized mucosa width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH).

279 attempted or failed mechanical thrombectomy (MT) and B) successful MT.

280 ites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients.

281 trafficking of incoming viral cores through MT stabilization.IMPORTANCE While microtubules (MTs) hav

282 alization occurring at an input stage fed to MT, and MT neurons cannot overturn this bias based on th

283 ssel diagnostic angiogram performed prior to MT led to a significant increase in procedure duration (

284 to counteract the recruitment of Kinesin to MTs.

285 all the study groups were observed together, MT levels were positively correlated with clinical param

286 Muscarinic toxins (MTs) are natural toxins produced by mamba snakes that pr

287 This study used magnetization transfer (MT) imaging to quantify white matter integrity in 78 sub

288 ty values (LC-CR) in magnetization-transfer (MT) images from the Cambridge Centre for Ageing and Neur

289 tion (measured using Magnetisation Transfer, MT) was significantly associated with a disinhibition ph

290 he hypothesis that the menopause transition (MT) contributes to the increase in coronary heart diseas

291 While diffusion along wild-type MT is performed in steps of dimeric tubulin, the removal

292 Patients who underwent MT to treat distal ICA occlusions between July 2012 and

293 ral data and computer simulations using a V1-MT model suggest that the contrast dominance found with

294 This in vivo MT phenotype was reproduced in vitro when cells were co-

295 When MT was positive, thyroidectomy was more often utilized (

296 We assessed whether MT performed on single-plane (SP) is equivalent in terms

297 While both Ag(+) and Cd(2+) react with MT to yield cooperative products, i.e., Ag(4)-MT and Cd(

298 R(up) correlated inversely with %MT (r=-0.72, P<0.001) and %IT (r=-0.62, P<0.001) of arte

299 largely be explained by normalization within MT.

300 hod by mapping metal-binding sites of Zn(7-x)MT species using a bottom-up MS approach with respect to