ライフサイエンスコーパス: N-acetylglucosamine

1 glucosamine (neosamine) series prepared from N-acetylglucosamine.

2 as well as UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.

3 osidic linkages of N-acetylgalactosamine and N-acetylglucosamine.

4 etic reactions involving uridine diphosphate N-acetylglucosamine.

5 nnose, alpha-glucose, beta-glucose, and beta-N-acetylglucosamine.

6 -linked sialic acid, galactose, and bisected N-acetylglucosamine.

7 ersion of UDP-N-acetylgalactosamine with UDP-N-acetylglucosamine.

8 e (OGT) modifies intracellular proteins with N-acetylglucosamine.

9 , lipoprotein YceK, toxin HicA, or MurA (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) suppresse

10 iotic identified two signaling muropeptides (N-acetylglucosamine-1,6-anhydro-N-acetylmuramyl pentapep

11 UDP-GlcNAc biosynthesis, converting UTP and N-acetylglucosamine-1-phosphate (GlcNAc-1P) to UDP-GlcNA

12 Eight N-acetylglucosamine-1-phosphate and N-acetylgalactosamin

13 Engineering a mutation in N-acetylglucosamine-1-phosphate transferase subunits alp

14 which encodes the alpha and beta subunits of N-acetylglucosamine-1-phosphate transferase.

15 ical and chemoenzymatic syntheses relying on N-acetylglucosamine-1-phosphate uridylyltransferase (Glm

16 in the mammalian transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylgluco

17 UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosp

18 beta subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (phosphotransfe

19 The Golgi-resident N-acetylglucosamine-1-phosphotransferase (PT) complex is

20 ngineered to carry a mutation in the Gnptab (N-acetylglucosamine-1-phosphotransferase subunits alpha/

21 lysosomal storage disorder caused by loss of N-acetylglucosamine-1-phosphotransferase, which tags lys

22 e protein with key enzymatic activities, UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine

23 Using UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kina

24 the key enzyme of sialic acid biosynthesis, N-acetylglucosamine 2-epimerase/N-acetylmannosamine kina

25 d paucimannosylation (mannose(1-3)fucose(0-1)N-acetylglucosamine(2)Asn).

26 hesis of sialic acid is the bifunctional UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kina

27 acetylmannosamine kinase (MNK) domain of UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kina

28 ate (UDP)-sugar donors, UDP-4-deoxy-4-fluoro-N-acetylglucosamine (4FGlcNAc) and UDP-4-deoxy-4-fluoro-

29 Sulf1 codes for an N-acetylglucosamine 6-O-endosulfatase, an enzyme that sp

30 Mice deficient in N-acetylglucosamine-6-O-sulfotransferase-1 (GlcNAc6ST-1)

31 nuclear cells and identified 2 autoantigens, N-acetylglucosamine-6-sulfatase (GNS) and filamin A (FLN

32 Uridine diphospho-N-acetylglucosamine, a product of the hexosamine synthet

33 -1,4-linked glucosamine (deacetylated/D) and N-acetylglucosamine (acetylated/A) units.

34 UDP-N-acetylglucosamine acyltransferase (LpxA) and UDP-3-O-(

35 UDP-N-acetylglucosamine acyltransferase (LpxA) and UDP-3-O-(

36 rease of the structures containing bisecting N-acetylglucosamine along with bi- and trisialylated tri

37 verted by epimerization to the corresponding N-acetylglucosamine analog by the epimerase N-acetylgala

38 ent resulting in IgG molecules with only one N-acetylglucosamine and a fucose residue was fully able

39 en the C6 and C1 hydroxyl groups of mannose, N-acetylglucosamine and glucose respectively.

40 ide based NPs that incorporate both sulfated N-acetylglucosamine and hydrophobic monomers were optimi

41 C in a ligand-free form, in complex with the N-acetylglucosamine and N-acetylgalactosamine products o

42 These structures showed N-acetylglucosamine and N-acetylgalactosamine to be reco

43 in to catalyze the in vitro incorporation of N-acetylglucosamine and N-acetylgalactosamine to oligosa

44 ration-dependent manner and was inhibited by N-acetylglucosamine and N-acetylgalactosamine.

45 typical M. xanthus lipids, fucose, mannose, N-acetylglucosamine and N-acetylgalactoseamine carbohydr

46 a repeating beta-1,4-linked disaccharide of N-acetylglucosamine and N-acetylmuramic acid appended wi

47 con esculentum lectin, which recognizes poly-N-acetylglucosamine and poly-N-acetyllactosamine.

48 all producing an identical polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

49 nT2 able to utilize both uridine diphosphate N-acetylglucosamine and uridine diphosphate N-acetylgala

50 on three different carbon sources (glucose, N-acetylglucosamine, and glycerol).

51 ng cell wall precursors, UDP-Glucose and UDP-N-acetylglucosamine are efficiently used to initiate tra

52 tone O-GlcNAcylation (O-GlcNAc=O-linked beta-N-acetylglucosamine) are largely unexplored.

53 f successive coupled enzyme assays using UDP-n-acetylglucosamine as the initial sugar substrate.

54 utinin (HA) of influenza virus with a single N-acetylglucosamine at each of the N-glycosylation sites

55 Similar to alginate and poly-beta-1,6 N-acetylglucosamine, bacterial cellulose is implicated i

56 nsfer of GalNAc to the simple sugar acceptor N-acetylglucosamine-beta-p-nitrophenol (GlcNAcbeta-pNP)

57 l trisaccharide [N-acetylgalactosamine-beta3-N-acetylglucosamine-beta4-(phosphate-6-)mannose] is requ

58 activity, resulting in higher levels of UDP-N-acetylglucosamine biosynthesis and protein O-GlcNAcyla

59 mutation using both the UDP-glucose and UDP-N-acetylglucosamine bound structures of the wild-type pr

60 eptor endocytosis and signaling by promoting N-acetylglucosamine branching of Asn (N)-linked glycans.

61 n of uridyldiphospho-3-O-(R-hydroxydecanoyl)-N-acetylglucosamine by the enzyme LpxC.

62 Inhibition of hexokinase by N-acetylglucosamine causes its dissociation from mitocho

63 f et al. (2016) report that detection of the N-acetylglucosamine component of peptidoglycan by the gl

64 ains confer recognitional specificity toward N-acetylglucosamine-containing signaling molecules, such

65 inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) in Gram-negative

66 s made of repeating N-acetylmuramic acid and N-acetylglucosamine disaccharides cross-linked by pentap

67 iosynthetic pathway (HBSP) that produces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine mod

68 the pools of UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, GDP-mannose, and GDP-fucose in Plas

69 nthase 1-3 (HAS1-3) isoenzymes that transfer N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA)

70 t sugar-aromatic interactions, with glucose, N-acetylglucosamine (GlcNAc) and mannose in between.

71 tion of nucleocytoplasmic proteins with beta-N-acetylglucosamine (GlcNAc) and regulates numerous biol

72 in particular with higher levels of beta-1,6-N-acetylglucosamine (GlcNAc) branched N-glycans.

73 e production of the high value nutraceutical N-acetylglucosamine (GlcNAc) could be balanced and optim

74 tion is altered by deleting two Bdellovibrio N-acetylglucosamine (GlcNAc) deacetylases, one of which

75 N-acetylglucosamine (GlcNAc) exists ubiquitously as a co

76 diate addition and removal, respectively, of N-acetylglucosamine (GlcNAc) from intracellular protein

77 O-GlcNAc transferase (OGT), which transfers N-acetylglucosamine (GlcNAc) from the nucleotide sugar d

78 ow outstanding affinities for derivatives of N-acetylglucosamine (GlcNAc) in aqueous solution.

79 e (OGT) mediates post-translational O-linked N-acetylglucosamine (GlcNAc) modification.

80 iously that varphi11 requires alpha- or beta-N-acetylglucosamine (GlcNAc) moieties on cell wall teich

81 erase that mediates the O-linked addition of N-acetylglucosamine (GlcNAc) moieties to Ser and Thr res

82 c proteins via O-linked addition of a single N-acetylglucosamine (GlcNAc) moiety.

83 described here, is attached to the remaining N-acetylglucosamine (GlcNAc) of IgG, using a mutant endo

84 To study the effect of short N-acetylglucosamine (GlcNAc) oligosaccharides on the phy

85 Dynamic cycling of N-Acetylglucosamine (GlcNAc) on serine and threonine res

86 wide variety of substrates which contain an N-acetylglucosamine (GlcNAc) residue to act as an 'accep

87 -translationally modified by adding O-linked N-acetylglucosamine (GlcNAc) residue to serine or threon

88 modules recognize polysaccharides containing N-acetylglucosamine (GlcNAc) residues including peptidog

89 e reducing end glucose of CPS and the beta-D-N-acetylglucosamine (GlcNAc) residues of peptidoglycan (

90 Chitin, a homopolymer of beta1,4-linked N-acetylglucosamine (GlcNAc) residues, is a key componen

91 polyrhamnose backbone with an immunodominant N-acetylglucosamine (GlcNAc) side chain, which is the ba

92 and consists of a polyrhamnose polymer, with N-acetylglucosamine (GlcNAc) side chains, which is an es

93 MX regulates formation of N-acetylglucosamine (GlcNAc) terminated N-glycans that p

94 f core-2 O-glycan branch through addition of N-acetylglucosamine (GlcNAc) to a core-1 O-glycan struct

95 The transfer of N-acetylglucosamine (GlcNAc) to Ser or Thr in cytoplasmi

96 modifies protein function by attaching beta-N-acetylglucosamine (GlcNAc) to serine and threonine res

97 ations of PgaB show a binding preference for N-acetylglucosamine (GlcNAc) to the N-terminal domain an

98 O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is the on

99 Here, we show that O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), an enzym

100 functional homologue of the Candida albicans N-acetylglucosamine (GlcNAc) transporter NGT1, and repre

101 rce for glycolysis and chitobiose to produce N-acetylglucosamine (GlcNAc), a key component of the bac

102 ieved by the treatment of P. aeruginosa with N-acetylglucosamine (GlcNAc), a widespread chemical pres

103 Various stimuli, including N-acetylglucosamine (GlcNAc), induce the fungal pathogen

104 nthesis of a tetra-antennary glycan that has N-acetylglucosamine (GlcNAc), N-acetyllactosamine (LacNA

105 ementation of culture media with uridine and N-acetylglucosamine (GlcNAc), precursors for the hexosam

106 ranslational modification with O-linked beta-N-acetylglucosamine (GlcNAc), promoted apoptosis through

107 em to form hyphae in response to the inducer N-acetylglucosamine (GlcNAc), suggesting that a basal le

108 n death domain-containing host proteins with N-acetylglucosamine (GlcNAc), thereby blocking extrinsic

109 nary glycan [A3(2,4,2) type] terminated with N-acetylglucosamine (GlcNAc), which is generated by N-ac

110 We previously demonstrated that certain N-acetylglucosamine (GlcNAc)-containing polysaccharides

111 from the cheaper and commercially available N-acetylglucosamine (GlcNAc).

112 nine residues modified by the monosaccharide N-acetylglucosamine (GlcNAc).

113 s are mainly composed of virally synthesized N-acetylglucosamine (GlcNAc).

114 r results of many cysteine residues bound to N-acetylglucosamine (GlcNAc).

115 lin, demonstrating that the 6-O-sulfation of N-acetylglucosamine (GlcNAc-6-O-sulfation) is highly con

116 ain lysine residues (+128.1 Da), and loss of N-acetylglucosamine (GlcNAc; -203.1 Da).

117 osamine transferase (OGT), and O-linked beta-N-acetylglucosamine hydrolase in control and IPAH cells

118 erial cells as demonstrated by inhibition of N-acetylglucosamine incorporation into polymeric cell wa

119 N-Acetylglucosamine is a key component of bacterial and

120 In H. jecorina-produced HjCel3A, a single N-acetylglucosamine is present at both sites, whereas in

121 nitoring the relative abundance of bisecting N-acetylglucosamine is relevant to physiological process

122 Also, N-acetylglucosamine is selectively oxidized at C3.

123 Chitin, a biopolymer of N-acetylglucosamine, is abundant in invertebrates and fu

124 sion of chitin, a beta-1,4 linked polymer of N-acetylglucosamine, is of major interest in areas varyi

125 Specificity studies with human N-acetylglucosamine kinase and hexokinase IV indicated a

126 izes residues that are already modified with N-acetylglucosamine, likely by converting into a relaxed

127 O-linked N-acetylglucosamine linkage (O-GlcNAcylation) to serine

128 phosphate-N-acetylmuramic acid(pentapeptide)-N-acetylglucosamine (lipid II), which is readily accessi

129 s for a unique phosphotransferase system and N-acetylglucosamine metabolism suggests an important eco

130 roduces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine modification (O-GlcNAcylation) of pr

131 ated by cAMP (EPAC), involving also O-linked N-acetylglucosamine modification downstream of the hexos

132 MCs resulted in reduced global O-linked beta-N-acetylglucosamine modification levels and abrogated PA

133 We measured the levels of O-linked beta-N-acetylglucosamine modification, O-linked beta-N-acetyl

134 biosynthetic pathway, which allows O-linked N-acetylglucosamine modifications of proteins.

135 the addition of the phosphothreonine to the N-acetylglucosamine moiety and CD0243 transfers the meth

136 trongest interactions are established by the N-acetylglucosamine moiety in the central region of the

137 composed of N-acetylmuramic acid-(beta-1,4)-N-acetylglucosamine (MurNAc-GlcNAc) disaccharides associ

138 ing amino sugars [i.e., N-acetylmuramic acid-N-acetylglucosamine (MurNAc-GlcNAc)] from attached pepti

139 he enzymes phosphomannomutase (PMM), phospho-N-acetylglucosamine mutase (PAGM) and phosphoglucomutase

140 to the monosaccharides l-fucose, d-mannose, N-acetylglucosamine, N-acetylgalactosamine, and galactos

141 g uniform responses (d-lactose, d-galactose, N-acetylglucosamine, N-acetylneuraminic acid), 'all-or-n

142 in vitro in the presence of acetyl-CoA, UDP- N-acetylglucosamine, NADPH, and ATP, we have developed a

143 ing azides and alkynes were installed on tri-N-acetylglucosamine (NAG)3, a PG mimic, as well as PG is

144 tional addition and removal of O-linked beta-N-acetylglucosamine (O-GlcNAc) also occurs on serine res

145 ation controlled by the enzyme O-linked-beta-N-acetylglucosamine (O-GlcNAc) glycosyltransferase as co

146 hesis and impaired addition of O-linked beta-N-acetylglucosamine (O-GlcNAc) groups to proteins import

147 lear and cytosolic proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc) has been shown to play an

148 mic post-translational modification O-linked N-Acetylglucosamine (O-GlcNAc) has emerged as an attract

149 e (OGA) is an enzyme harboring O-linked beta-N-acetylglucosamine (O-GlcNAc) hydrolase and cryptic lys

150 O-Linked beta-N-acetylglucosamine (O-GlcNAc) is a carbohydrate post-tr

151 O-Linked beta-N-acetylglucosamine (O-GlcNAc) is a post-translational m

152 O-linked N-acetylglucosamine (O-GlcNAc) is a post-translational m

153 slational protein modification O-linked beta-N-acetylglucosamine (O-GlcNAc) is a proposed nutrient se

154 O-linked N-acetylglucosamine (O-GlcNAc) is a reversible posttrans

155 Glycosylation with O-linked beta-N-acetylglucosamine (O-GlcNAc) is one of the protein gly

156 Cellular O-linked N-acetylglucosamine (O-GlcNAc) levels are modulated by t

157 O-Linked beta-N-acetylglucosamine (O-GlcNAc) modification found on the

158 We studied O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of contracti

159 O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of cytoplasm

160 refute the hypothesis of extensive O-linked N-acetylglucosamine (O-GlcNAc) modification of endogenou

161 Although the O-linked N-acetylglucosamine (O-GlcNAc) modification of the RNA p

162 O-linked N-acetylglucosamine (O-GlcNAc) modifications regulate th

163 show that Oct1 is modified by O-linked beta-N-acetylglucosamine (O-GlcNAc) moieties.

164 ttranslational modification by O-linked beta-N-acetylglucosamine (O-GlcNAc) moieties.

165 osttranslational modification by beta-linked N-acetylglucosamine (O-GlcNAc) on HDAC4 were investigate

166 posttranslational addition of O-linked beta-N-acetylglucosamine (O-GlcNAc) on intracellular proteins

167 Dynamic cycling of O-linked beta-N-acetylglucosamine (O-GlcNAc) on nucleocytoplasmic prot

168 entification and precise mapping of O-linked N-acetylglucosamine (O-GlcNAc) post-translational modifi

169 Evidence suggests that the O-linked N-acetylglucosamine (O-GlcNAc) posttranslational modific

170 this study, we demonstrate that the O-linked N-acetylglucosamine (O-GlcNAc) processing enzymes, O-Glc

171 ost-translational modification O-linked beta-N-acetylglucosamine (O-GlcNAc) regulates thousands of nu

172 cess of interest is the addition of O-linked N-acetylglucosamine (O-GlcNAc) residues onto nuclear and

173 i-inflammatory function of the O-linked beta-N-acetylglucosamine (O-GlcNAc) signaling associated with

174 ected role of nutrient-sensing O-linked beta-N-acetylglucosamine (O-GlcNAc) signaling in suppressing

175 d posttranslational modification by O-linked N-Acetylglucosamine (O-GlcNAc) stabilizes FOXP3 and acti

176 is the covalent addition of an O-linked beta-N-acetylglucosamine (O-GlcNAc) sugar moiety to hydroxyl

177 ined, in part, by the attachment of O-linked N-acetylglucosamine (O-GlcNAc) to proteins (O-GlcNAcylat

178 toplasmic and nuclear protein by transfer of N-acetylglucosamine (O-GlcNAc) to serine and threonine h

179 slational addition of a single O-linked beta-N-acetylglucosamine (O-GlcNAc) to serine or threonine re

180 O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an e

181 Here we demonstrate that O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is requ

182 The nutrient sensor O-linked-beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) modifie

183 N-Acetylglucosamine (O-GlcNAc) transferase (OGT) regulat

184 how that DELLAs are modified by the O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) SECRET

185 amine biosynthesis pathway and O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) to pote

186 t TET2 and TET3 associate with O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT), an enz

187 We identifed O-linked-N-acetylglucosamine (O-GlcNAc) transferase (OGT), an X-l

188 AMPK directly phosphorylates O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT).

189 ent-responsive glycosyltransferase, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT).

190 We demonstrate that O-linked N-acetylglucosamine (O-GlcNAc), a post-translational mod

191 osttranslational modification, O-linked beta-N-acetylglucosamine (O-GlcNAc), in NSCs promotes a glial

192 One such signal, O-linked beta-N-acetylglucosamine (O-GlcNAc), is an essential post-tra

193 ugh a modification in the amount of O-linked N-acetylglucosamine (O-GlcNAc)-modified proteins and in

194 ion of serine/threonine residues by O-linked N-acetylglucosamine (O-GlcNAc).

195 covalent modification of CaMKII by O-linked N-acetylglucosamine (O-GlcNAc).

196 osolic and nuclear proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc).

197 Glycosylation with O-linked beta-N-acetylglucosamine (O-GlcNAcylation) is a reversible po

198 al modification of proteins with beta-linked N-acetylglucosamine (O-GlcNAcylation) via overexpression

199 creased modification of proteins by O-linked N-acetylglucosamine (O-GlcNAcylation).

200 ride beta-N-acetylmuramic acid, (1-->4)-beta-N-acetylglucosamine of staphylococcal peptidoglycan.

201 ylation, sialylation, and level of bisecting N-acetylglucosamine of the IgG glycans.

202 tify the pattern of O-glycosylation (21 mono-N-acetylglucosamines) of its AST domain.

203 lammatory and stress responses, and O-linked N-acetylglucosamine (OGN) transferase (OGT), an enzyme t

204 the reaction of free MurA and substrate UDP-N-acetylglucosamine or isomer UDP-N-acetylgalactosamine.

205 o hydrolyze the beta-linkages joining either N-acetylglucosamine or N-acetylgalactosamine to a wide v

206 O-Linked beta-N-acetylglucosamine, or O-GlcNAc, is a dynamic post-tran

207 substrates (a mix of substrates, glutamine, N-acetylglucosamine, or pyruvate) revealed contrasting c

208 nally predicted putative miR-185 targets UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransfer

209 tact O antigen, a capsule mutant, and a poly-N-acetylglucosamine (PGA) mutant.

210 olysaccharide intercellular adhesin, or poly N-acetylglucosamine (PIA/PNAG).

211 Poly-N-acetylglucosamine (PNAG) is a major component of the S

212 The exopolysaccharide poly-beta-(1->6)-N-acetylglucosamine (PNAG) is a major structural determi

213 served microbial surface polysaccharide poly-N-acetylglucosamine (PNAG) that is expressed on numerous

214 e conserved cell surface polysaccharide poly-N-acetylglucosamine (PNAG) were effective at mediating r

215 , encoding the biosynthesis of poly-beta-1,6-N-acetylglucosamine (PNAG), a major biofilm matrix compo

216 ne isolate and found to be negative for poly-N-acetylglucosamine (PNAG)-like material by immunoblot a

217 roadly expressed microbial carbohydrate poly-N-acetylglucosamine (PNAG).

218 Chitin is a natural N-acetylglucosamine polymer and a major structural compo

219 Two intracellular enzymes, UDP-N-acetylglucosamine-polypeptide beta-N-acetylglucosaminy

220 UDP-N-acetylglucosamine pyrophosphorylase (UAP) is the final

221 mmy codes for the single UDP-N-acetylglucosamine pyrophosphorylase in Drosophila, and

222 2-FGFR1c2 can tolerate an HS chain having an N-acetylglucosamine residue at its non-reducing end.

223 hed to the proximal (reducing-terminal) core N-acetylglucosamine residue of N-glycans by beta1,4-link

224 calpha1,3 moiety attached to the distal core N-acetylglucosamine residue was detected.

225 matode glycan cores, specifically the distal N-acetylglucosamine residue; this result is in accordanc

226 N-glycan structure of seven mannosyl and two N-acetylglucosamine residues (Man7GlcNAc2) on misfolded

227 a linear tetrasaccharide that contained two N-acetylglucosamine residues and a free OH group gave tw

228 ieties of N-acetylneuraminic acid as well as N-acetylglucosamine residues and nucleophilic sites of a

229 f Cnm and strongly suggested the presence of N-acetylglucosamine residues attached to Cnm.

230 bonds between N-acetylmuramic acid (NAM) and N-acetylglucosamine residues with concomitant formation

231 e, alpha2-6-linked sialic acid, and bisected N-acetylglucosamine, respectively.

232 arbon substrates, For example, for growth on N-acetylglucosamine, S. marcescens exhibits high pentose

233 illus niger in deglycosylated and Asn-linked N-acetylglucosamine-stub forms reveal a 10(2/3)-turn par

234 r magnetic resonance and shown to contain an N-acetylglucosamine substituted with a phosphorylated N-

235 tion of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates si

236 ble for the selective phosphorylation of the N-acetylglucosamine sugar in a teicoplanin A2-2 derivati

237 s dynamically modified with an O-linked beta-N-acetylglucosamine sugar in response to hypoxia.

238 The enzymatic addition of a single beta-D-N-acetylglucosamine sugar molecule on serine and/or thre

239 ation consisting of the addition of a single N-acetylglucosamine sugar to serine and threonine residu

240 evated post-translational addition of beta-D-N-acetylglucosamine sugars to nuclear and cytoplasmic pr

241 Evidently, hexosamine pathway activation or N-acetylglucosamine supplementation induces distinct pro

242 ric forms of either N-acetylgalactosamine or N-acetylglucosamine target hepatic antigen-presenting ce

243 The dynamic cycling of N-acetylglucosamine (termed O-GlcNAcylation) on serine o

244 esidue is in closer proximity (7.6 A) to the N-acetylglucosamine than the two other sugar rings prese

245 Chitin is a polymer of N-acetylglucosamine that is abundant and widely found in

246 lammasome activation is caused by release of N-acetylglucosamine that is detected in the cytosol by t

247 lytic itineraries for other sugars; for beta-N-acetylglucosamine, the key N-acetyl arm confounds the

248 These results demonstrate that glucose and N-acetylglucosamine, the most readily available chiral b

249 seK3, which is essential for the transfer of N-acetylglucosamine to arginine residues (arginine-GlcNA

250 acetylmannosamine kinase that transforms UDP-N-acetylglucosamine to N-acetylmannosamine (ManNAc) foll

251 nal modification involving O-linkage of beta-N-acetylglucosamine to Ser/Thr residues on target protei

252 ne such modification is addition of O-linked N-acetylglucosamine to serine or threonine residues, kno

253 modification involving the O-linkage of beta-N-acetylglucosamine to serine/threonine residues of memb

254 Addition of the N-glycan precursor N-acetylglucosamine to the growth medium slows aging in

255 functions as a ligase that adds the terminal N-acetylglucosamine to the lipooligosaccharide core of Y

256 They catalyze the addition of the N-acetylglucosamine to the N-acetyl-lactosamine repeat a

257 s involved in cell metabolism: O-linked beta-N-acetylglucosamine transferase (OGT) and isocitrate deh

258 O-Linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAc

259 O-Linked beta-N-acetylglucosamine transferase (OGT) is an essential hu

260 O-linked N-acetylglucosamine transferase (OGT) is found in all me

261 tumors from colon tumor cells with O-linked N-acetylglucosamine transferase (OGT) knockdown grew sig

262 that TRIM28 was complexed with O-linked beta-N-acetylglucosamine transferase (OGT) only in cells that

263 cetylglucosamine modification, O-linked beta-N-acetylglucosamine transferase (OGT), and O-linked beta

264 dues in proteins by the enzyme O-linked beta-N-acetylglucosamine transferase (OGT), whereas the enzym

265 ces an essential substrate for O-linked beta-N-acetylglucosamine transferase (OGT), which glycosylate

266 is a putative serine and threonine O-linked N-acetylglucosamine transferase (OGT).

267 amine biosynthetic pathway and OGT (O-linked N-acetylglucosamine transferase)-mediated protein O-GlcN

268 otentially encode an O-acetyltransferase, an N-acetylglucosamine transferase, and a KDO transferase c

269 C also interacts with the O-GlcNAc (O-linked N-acetylglucosamine) transferase SPINDLY required for pr

270 GOLPH3 supports incorporation of both core 2 N-acetylglucosamine-transferase 1 and alpha-2,6-sialyltr

271 to control the Golgi localization of core 2 N-acetylglucosamine-transferase 1.

272 that EXTL2 exhibited much stronger in vitro N-acetylglucosamine-transferase activity related to elon

273 SLC35A3 is considered the main UDP-N-acetylglucosamine transporter (NGT) in mammals.

274 galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) form hete

275 UDP-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (LpxA)

276 65000) as an ER-localized facilitator of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalacto

277 re we show that TpeL preferably utilizes UDP-N-acetylglucosamine (UDP-GlcNAc) as a sugar donor.

278 exosamine biosynthetic pathway, increase UDP-N-acetylglucosamine (UDP-GlcNAc) availability, and lead

279 d thatlymphostatin binds uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) but not UDP-glucose (UD

280 pathway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) for glycan synthesis an

281 The sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) is an essential metabol

282 Uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) is the donor sugar subs

283 The HBP end product UDP-N-acetylglucosamine (UDP-GlcNAc) is used in enzymatic po

284 rikingly, addition of the HBP metabolite UDP-N-acetylglucosamine (UDP-GlcNAc) to CRPC-like cells sign

285 tamine are precursors of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a substrate for cellul

286 -biosynthesis precursor, uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), was monitored by recor

287 In complex with the cosubstrate UDP-N-acetylglucosamine (UDP-GlcNAc),O-linked-GlcNAc transfe

288 to eventually synthesize uridine diphosphate N-acetylglucosamine (UDP-GlcNAc).

289 ules UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine (UDP-GlcNAc).

290 thway (HBP), to increase uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

291 DP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conj

292 el, ChiA variants with weaker binding of the N-acetylglucosamine unit either in substrate-binding sit

293 side the cell (to produce the monosaccharide N-acetylglucosamine), using this beta-glucan to obtain c

294 a five-member consortium of sialic acid and N-acetylglucosamine utilizers that impedes C. difficile'

295 t core alpha1,3-fucosylation of the proximal N-acetylglucosamine was abolished, the degree of galacto

296 ration of ethoximated and trimethylsilylated N-acetylglucosamines was developed.

297 nities for uncharged substrates (glucose and N-acetylglucosamine) were also enhanced, despite competi

298 ycans with different modifications including N-acetylglucosamine, which bisects the mannose core.

299 step in the synthesis of uridine diphosphate N-acetylglucosamine, which is required for the biosynthe

300 version of UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine while the bacterial enzyme cannot.

301 y beta4 addition of N-acetylgalactosamine to N-acetylglucosamine with formation of the N,N-diacetylla