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1 rel domain connected to a positively charged N-terminal extension.
2 interaction domains located at their unique N-terminal extension.
3 y unobserved HXH motif located in its unique N-terminal extension.
4 ke region and a approximately 400 amino acid N-terminal extension.
5 motif, but it also carries an arginine-rich N-terminal extension.
6 ontains an additional alpha-helix in a novel N-terminal extension.
7 ntiholin, S107, which differs by its Met-Lys N-terminal extension.
8 gth chains the groove is likely filled by an N-terminal extension.
9 sses a novel first exon that encodes a 51 aa N-terminal extension.
10 from restricted removal of the cTnI-specific N-terminal extension.
11 enylation domain, but only one containing an N-terminal extension.
12 der of the pilus, with the assistance of the N-terminal extension.
13 hile RGS4-3 encodes a 302 aa protein with an N-terminal extension.
14 immunoglobulin-like fold (pilin body) and an N-terminal extension.
15 weakly stimulates motor domains without the N-terminal extension.
16 , a variant of TUC-4a that includes a unique N-terminal extension.
17 w ionic strength upon addition of this extra N-terminal extension.
18 obed the protein-protein interactions of the N-terminal extension.
19 te nuclear localization signal in its unique N-terminal extension.
20 be sensitive to the nature of the protruding N-terminal extension.
21 mally stabilized form of Mcl1 due to a 13-aa N-terminal extension.
22 odulates the actin binding properties of the N-terminal extension.
23 d MCM2 are unusual in having long and unique N-terminal extensions.
24 h contain the DNA binding domain and various N-terminal extensions.
25 with DNA to analyse functional roles of the N-terminal extensions.
26 structure with structurally uncharacterised N-terminal extensions.
27 ic of other L23a family members and a unique N-terminal extension, absent from Saccharomyces cerevisi
28 g the HB-EGF membrane anchor, but lacking an N-terminal extension, activated EGFR during their transi
29 upport a model in which the isoform-specific N-terminal extensions affect chemomechanical coupling by
33 These and other results suggest that the N-terminal extension alters the accessibility of the sig
34 site of interaction of Mal3 with Tea2 is the N-terminal extension, although a weaker interaction is a
35 the channels include a 71 amino acid CLH-3a N-terminal extension and a 270 amino acid extension of t
36 regions unique to HO2: a 20-amino acid-long N-terminal extension and a C-terminal domain containing
38 s of Myo18Aalpha but includes an alternative N-terminal extension and a long serine-rich C terminus.
40 ed in the KE-rich region at the start of the N-terminal extension and appears to mediate ATP-independ
41 -24 (also PKA sites) in the cardiac-specific N-terminal extension and at Thr-144, a unique residue in
42 ric Mdv1-Fis1 complex that contains both the N-terminal extension and coiled-coil regions of Mdv1.
43 Surprisingly, the commonly cited V2-specific N-terminal extension and cysteines were found to be disp
46 ecular autoinhibitory mechanism involving an N-terminal extension and phosphorylation of tyrosine res
47 verall architectural topology; however, each N-terminal extension and pilin body has specific functio
48 e intrasubunit interactions between the cTnI N-terminal extension and the cTnI inhibitory peptide, wh
49 ating intramolecular interaction between the N-terminal extension and the inhibitory region of cTnI.
50 ity to the intrinsic effects of Motif 3, the N-terminal extension and their synergistic effect, and (
51 up I intron binding surface that includes an N-terminal extension and two small insertions (insertion
52 on those of bacterial TyrRSs, except for an N-terminal extension and two small insertions not found
53 eptides from ERAAP-deficient cells contained N-terminal extensions and had a different molecular comp
54 escribed nonintuitive design rules governing N-terminal extensions and identified successful extensio
55 These new compstatin peptides contain polar N-terminal extensions and non-natural amino acid substit
57 ), a histidine-tagged analogue containing an N-terminal extension, and five different terminus-trunca
58 interactions are lost after exit of the VP1 N-terminal extension, and that the RNA also interacts wi
59 ly of bacteria that contain MetAPs with such N-terminal extensions, and we classify these as MetAP ty
61 dimerization, neither the HRM region nor the N-terminal extension appeared to affect HO2 dynamics.
62 pe of a truncated form of DrDps1 without the N-terminal extensions appears as a dodecameric sphere, c
63 tor domain only or the motor domain plus the N-terminal extension are monomeric, whereas a construct
65 H16 that makes specific contacts with the S4 N-terminal extension, as well as a right-angle motif bet
69 ements of the zinc finger as well as a short N-terminal extension but is restricted to the switch and
71 ates the ATPase of constructs containing the N-terminal extension by decreasing the K0.5(MT) for stim
72 in vitro motility assay, suggesting that the N-terminal extension can act in a modular manner to incr
73 presence of calcium nor deletion of the MTIP N-terminal extension changed the speed of actin movement
76 lumen are synthesized in the cytosol with an N-terminal extension consisting of transient signals for
79 bacterial orthologs, plant UreGs possess an N-terminal extension containing a His- and Asp/Glu-rich
80 to all viral polymerases as well as a large N-terminal extension containing a kinase-like fold and i
86 escued null or control (Dmlc2(+)), truncated N-terminal extension (Dmlc2(Delta2-46)), disrupted myosi
87 HK97, T5 encodes the scaffold function as an N-terminal extension (-domain) to the major head protein
91 eal a 'budded' PH domain fold, possessing an N-terminal extension forming an integral part of the ove
92 gondii lacks this type of translocator, the N-terminal extension from the Plasmodium falciparum sequ
93 rge spacer insert domain and a portion of an N-terminal extension function cooperatively to increase
94 cardiac stress to remove the unique cardiac N-terminal extension functions to improve cardiac contra
97 show that the native signal peptide, or any N-terminal extension, has an inhibitory effect on SplB.
99 on of an invariant asparagine residue in the N-terminal extension, however, restored cotranslational
100 ting evidence as to the functions of the BNP N-terminal extension; however, this has never been asses
101 led oxidation of Fe(2+), and possess a short N-terminal extension implicated in stabilizing cellular
102 ers of the ABCC subfamily, Ycf1p contains an N-terminal extension in addition to its ABC "core" domai
103 rough the ASTS USP7 binding motif within its N-terminal extension in an identical manner with other k
106 especially the role of the cardiac specific N-terminal extension in modulating actomyosin interactio
108 consensus sequence, and participation of the N-terminal extension in the formation of the substrate-b
111 Analysis of Trx h9 revealed a 17-amino acid N-terminal extension in which the second Gly (Gly(2)) an
112 ewly identified role of the ferritin subunit N-terminal extensions in gating Fe(2+) exit from the cyt
114 presentation of peptide precursors with long N-terminal extensions in TPPII gene-trapped embryonic fi
119 Previous structural studies showed that the N-terminal extension is disordered in the absence of DNA
121 revented virus recovery, suggesting that the N-terminal extension is essential for virus viability.
122 sis revealed that this glycine-arginine rich N-terminal extension is present outside the animal kingd
124 he molecules of the crystal, part of the RLC N-terminal extension is seen in atomic detail and forms
126 of available databases shows that the unique N-terminal extension is shared by multiple insect lineag
127 ed protein alpha-synuclein with a 10-residue N-terminal extension is shown to form a stable tetramer
128 2 ubiquitin conjugation enzyme with a unique N-terminal extension, is a novel USP7-interacting protei
130 ar-encoded as their precursors containing an N-terminal extension known as the transit peptide (TP).
131 activity of the protease precursor), and the N-terminal extension makes transient intra- and intersub
134 The active site at the interface of the N-terminal extension, methyltransferase, and beta-barrel
135 Additionally, the effect of one of the L3 N-terminal extension mutants on the interaction between
138 dgd1-1 mutant of Arabidopsis in fusion with N-terminal extensions (NDGD1 and NDGD2) targeting to the
139 Most strikingly, deletion of ARHI's unique N-terminal extension nearly abolished its inhibitory eff
140 that phosphorylation of Ser-251 in the Ycf1p N-terminal extension negatively regulates activity.
142 ted using specific primers with deletions of N-terminal extension (NT) (named betaA3-NT), N-terminal
143 nts of betaA3-crystallin were generated: (i) N-terminal extension (NTE) 21 amino acids (betaA3[21] mu
144 erminal localization module, organized in an N-terminal extension (NTE) and a tetratricopeptide repea
147 replaced with a beta-strand formed from the N-terminal extension (Nte) of an incoming pilus subunit
148 Here we demonstrate that the unstructured N-terminal extension (NTE) of ClpS enters the ClpA proce
149 eplication system, we find that the flexible N-terminal extension (NTE) of Mcm2 promotes the stable r
153 aracterized by a approximately 32 amino acid N-terminal extension (NTE), the function of which remain
155 RNA(Lys) Higher eukaryotic LysRSs possess an N-terminal extension (Nterm) previously shown to facilit
158 binding and autophosphorylation, but has an N-terminal extension of 370 aa, lacking homology with an
159 catalytically active construct, including an N-terminal extension of 60 residues prior to the kinase
160 se that new gene overlaps generally arise by N-terminal extension of a downstream gene, creating a no
163 maltase with known structure and exhibits an N-terminal extension of about 140 residues, in contrast
165 change, occurring at the usher, in which the N-terminal extension of an incoming subunit completes th
166 nslated regions were noncanonical and led to N-terminal extension of annotated proteins or translatio
167 an thymidylate synthase (TS) enzymes have an N-terminal extension of approximately 27 amino acids tha
168 ion (ECF) sigma factor PvdS but possesses an N-terminal extension of approximately 29 amino acids tha
169 gated whether PIP(2) controls binding of the N-terminal extension of ARF1 to ASAP1's PH domain and th
170 llins were modified by removal of either the N-terminal extension of betaA3 (rbetaA3Ntr) or betaB2 (r
173 Overall, our results demonstrate that the N-terminal extension of BNP is essential to virus viabil
175 covered phosphorylation sites located in the N-terminal extension of cardiac troponin I (S4, S5, Y25)
177 t engagement of the intrinsically disordered N-terminal extension of ClpS by ClpA is both necessary a
178 These findings indicate that removal of the N-terminal extension of cTnI via restricted proteolysis
183 d donor-strand complementation, in which the N-terminal extension of each subunit, the donor strand,
186 nd proline-rich ligands, we suggest that the N-terminal extension of ELC interacts with actin and mod
187 our data support that the mRNA encoding the N-terminal extension of hcArgRS has the capacity of inde
188 the DNA-binding domain of GAL4 fused to the N-terminal extension of HDAC5 and the VP16 transcription
197 the myristoylated capsid protein VP4 and the N-terminal extension of the capsid protein VP1, both of
198 orthologues of Zta suggest that a conserved N-terminal extension of the consensus B-ZIP domain is re
199 he SH3 domain facilitates the binding of the N-terminal extension of the essential light chain isofor
201 nsect cells is multiply phosphorylated on an N-terminal extension of the protein that contains a high
203 domains of TnC, providing evidence that the N-terminal extension of TnI interacts with the N-termina
204 additional E2-E3 interaction mediated by the N-terminal extension of UbcH10 regulates APC activity.
205 degradation by polypeptides that include the N-terminal extension of VP1 and capsid protein VP4.
206 d identity) revealed a glycine-arginine rich N-terminal extension of ~100 amino acids that, given pre
207 ggregation kinetics of Abeta42 variants with N-terminal extensions of 5-40 residues, and transmission
208 and indicated that truncation occurs within N-terminal extensions of beta-crystallins during lens ma
210 of a set of conserved serine residues in the N-terminal extensions of class II HDACs creates binding
215 EF loop of VP2, the GH loop of VP3, and the N-terminal extensions of VP1 and VP2, which, in retrospe
217 ucleotide exchange activity requires a novel N-terminal extension on the DH domain that is predicted
219 ha is soluble, either phosphorylation of its N-terminal extension or DNA binding promotes the formati
220 trate that L27 variants with an un-cleavable N-terminal extension, or lacking the extension (pre-clea
221 y, all plant HMGLs also contained a specific N-terminal extension (P100) that is located between the
222 N-terminal extension (NT) (named betaA3-NT), N-terminal extension plus motif I (named betaA3-NT + I),
223 xtension plus motif I (named betaA3-NT + I), N-terminal extension plus motifs I and II (named betaA3-
224 ning dimers, tetramers and octamers, but the N-terminal extension present in IncC1 favours nucleotide
225 efining a subtilisin-like fold with a unique N-terminal extension previously proposed to function as
226 of human PDE3A1 at a PKA site in its unique N-terminal extension promotes its incorporation into SER
227 -ray scattering (SAXS) results show that the N-terminal extensions protrude from the spherical shell
228 e new subunits were dictated by the specific N-terminal extension provided and were consistent with t
233 antibody directed against the alpha-subunit N-terminal extension region or by deletion of the N-term
235 nuclear localization of BNP, with the entire N-terminal extension required for this to function effic
236 cal PTP domain (residues 44-339) and a short N-terminal extension (residues 1-43) that functions to d
237 l (betaalpha)6-barrel fold with a disordered N-terminal extension (residues 45-74) and a partially or
238 nsion of this peptide has little effect, but N-terminal extension results in higher maximal velocity
240 at Cul3 interaction is dependent on a unique N-terminal extension sequence that packs against the 3-b
241 the structure uncovers a unique role for the N-terminal extension sequence, which stabilizes helix al
242 While the SEC14 domain and its CRAL-TRIO-N-terminal extension serve general membrane attachment o
244 nscriptional regulators and also contains an N-terminal extension similar to the Ni(2+)-binding C-ter
245 duced after radiation damage and contains an N-terminal extension similar to those of proteins involv
247 during autoactivation at higher pH contained N-terminal extensions (starting at 6 and 14 amino acid r
248 ra crassa MMM1, which naturally lacks a long N-terminal extension, substituted for loss of Mmm1p in b
249 ophobic cleft while two other helices and an N-terminal extension target a discrete surface formed la
250 v1 has a modular structure, consisting of an N-terminal extension that binds Fis1, a central coiled c
251 approximately 150 amino acids as well as an N-terminal extension that consists of two carbohydrate b
252 I isoforms, cardiac troponin I (cTnI) has an N-terminal extension that contains phosphorylation sites
253 troponin I (cTnI) isoform contains a unique N-terminal extension that functions to modulate activati
254 transcription, the Ton box is preceded by an N-terminal extension that interacts with the inner-membr
255 ns an evolutionarily conserved 50-amino-acid N-terminal extension that is absent from the NP of influ
256 e only identified mutation within its unique N-terminal extension that is associated with hypertrophi
257 resembles a classical signal peptide plus an N-terminal extension that is conserved in other autotran
259 reus and other Firmicutes is encoded with an N-terminal extension that is not present in most Gram-ne
260 unit protein L27 is encoded with a conserved N-terminal extension that is removed to expose residues
261 inactive mini-precursor with a four-residue N-terminal extension that mimics the transframe region p
262 se that mitochondrial Cbp3 homologs carry an N-terminal extension that positions the conserved C-term
263 D contains an approximately 170-residue-long N-terminal extension that structurally mimics a dimer-di
264 find that TatA in Prov. stuartii has a short N-terminal extension that was atypical of TatA proteins
267 c structural elements (a beta hairpin and an N-terminal extension) that contribute to its substrate s
268 e nuclear localization signal (NLS) in their N-terminal extension, the 18-kDa FGF-2 does not contain
269 ith the exception of a unique 129-amino acid N-terminal extension, the ACH2 protein is 17-36% identic
270 letion constructs were prepared in which the N-terminal extension, the C-terminal extension or both e
271 include a zinc-binding site and a hook-like N-terminal extension, the latter representing a hallmark
272 pFurH134Y), which represent mutations in the N-terminal extension, the regulatory metal binding site
273 As the NP of influenza A virus lacks this N-terminal extension, these viruses may have evolved sep
274 o process viral peptides with C-terminal and N-terminal extensions through their proteasomal and cyto
275 cific E2-E3 interface and regulation via its N-terminal extension to limit APC activity for substrate
277 vide structural and biochemical data on UBA5 N-terminal extension to understand its contribution to U
279 ted data reveal the relative position of the N-terminal extensions to the dodecameric sphere in solut
280 s to the trimming of peptides with very long N-terminal extensions, TPPII is not essential for genera
282 diminished power output parameters with the N-terminal extension truncation and phosphorylation site
284 f both N- and C-terminal tails, but only the N-terminal extension undergoes mechanical removal, there
286 In this study, pilus subunits in which the N-terminal extension was either deleted or swapped with
288 C) and the physiological significance of its N-terminal extension, we generated transgenic (Tg) mice
289 nuclein construct that contains a 10-residue N-terminal extension, which forms multimers when isolate
290 conserved among bacteria containing the L27 N-terminal extension, which performs post-translational
292 f actomyosin, through the interaction of its N-terminal extension with actin and its C-terminal lobe
295 fide transporter, CcdA, which all display an N-terminal extension with respect to their bacterial cou
296 locating within the protein, or swapping its N-terminal extension with that of other subunits altered
298 Saccharomyces cerevisiae ProRS possesses an N-terminal extension with weak homology to a bacterial-s
299 s, which we named AtRibF1 and AtRibF2, carry N-terminal extensions with characteristics of organellar
300 ble tolerance for accommodating the fly L23a N-terminal extension within the structure of the yeast r