ライフサイエンスコーパス: N-terminal portion

1 the presence of STIM1 and the conserved Orai N-terminal portion.

2 ng either the entire L11 protein or just the N-terminal portion.

3 -binding domain was situated in the flexible N-terminal portion.

4 in with the virion components located in the N-terminal portion.

5 as a putative DNA helicase is encoded by the N-terminal portion.

6 mbrane NRG isoforms with this CRD within the N-terminal portion.

7 inding, one on the C-terminal and one on the N-terminal portion.

8 tion of the p21 core protein and lacking the N-terminal portion.

9 Previous NMR studies indicated that the N-terminal portion (1ADSGE5) of unphosphorylated fibrino

10 ptually subdividing 1 into three regions: an N-terminal portion, a central statine-containing core, a

11 ll as that of FHL, interacting with the LAF1 N-terminal portion and the HFR1 C-terminal region.

12 with truncated Prx1 proteins showed that the N-terminal portion and the homeodomain of Prx1 were nece

13 of proteins containing the PDZ domain in the N-terminal portion and the LIM domain in the C-terminal

14 ly targeted to the nucleus by signals in its N-terminal portion, and the full-length protein accumula

15 The N-terminal portion (codons 1 to 24) of the 5'-proximal o

16 ernal leader could function even if the most N-terminal portion contained negative charges in the fir

17 osed of two subdomains, a largely disordered N-terminal portion containing three known phosphorylatio

18 raged 55 +/- 2%, suggesting that the missing N-terminal portion contains most of the alpha-helical st

19 The N-terminal portion contains the methylated DNA binding d

20 nce of a VHS (Vps27p/Hrs/Stam) domain in the N-terminal portion followed by a GAT (GGA and Tom) domai

21 the levels of cellular LRP and releases its N-terminal portion in the extracellular milieu while the

22 MD simulations suggested that the remaining N-terminal portion in the non-functional Orai1 N-truncat

23 two sets of constructs were created in which N-terminal portions (including either VRI-IV or only VRI

24 alone revealed low deuteration levels in the N-terminal portion, indicating that this region containe

25 cytoplasmic tail, PKD1(115-226), but not the N-terminal portion, induced a large, Ca(2+)-permeable ca

26 portion is essential for clipping, while the N-terminal portion is sufficient for DSB end-resection.

27 c(y) revealed that its signal sequence-like N-terminal portion is uncleaved; hence, it is anchored t

28 One, which is located in the N-terminal portion, is shorter than but similar in seque

29 al analyses it is shown that domain C of the N-terminal portion, located adjacent to the helicase cat

30 n in muscle and adipose tissues and that its N-terminal portion may be critical for APPL1 function.

31 ces in the amino acid residues in the amino (N)-terminal portion of the kinase domain of RAF isoforms

32 either in small proteins, or it makes up the N-terminal portion of a larger protein, usually a protei

33 p going through the DNA minor groove, or the N-terminal portion of a long helix binding in the DNA ma

34 of our peptide sequences and represented the N-terminal portion of a protein containing a signal pept

35 Deletion of the N-terminal portion of Acf1 (or its homologue in yeast) a

36 of AHR transactivation by AHRR involves the N-terminal portion of AHRR; does not involve competition

37 Therefore, the role of the N-terminal portion of ALL-1 is to direct the protein to

38 myc gene was abolished after deletion of the N-terminal portion of alpha-enolase.

39 rt of the binding pocket that recognizes the N-terminal portion of alpha-factor and is involved in th

40 erminal tail (residues 1-9), followed by the N-terminal portion of alpha-helix 1 (residues Cys-11, Gl

41 The N-terminal portion of alphaL is predicted to contain a b

42 The N-terminal portion of AML1, which is retained in AML1/ET

43 of 60-77-residue components identical to the N-terminal portion of apolipoprotein A-I (Apo A-I).

44 a2NTD (the N-terminal portion of Atp6v0a2) and secreted chemokine-c

45 The N-terminal portion of AvrPtoB is sufficient for its viru

46 d region (sigma(70) NCR) and a region in the N-terminal portion of beta' that appears to functionally

47 study, we used a monoclonal antibody to the N-terminal portion of beta-APP to examine how the immuno

48 motif present in the PC1 CTT as well as the N-terminal portion of beta-catenin.

49 The N-terminal portion of BFCOL1 contains its DNA-binding do

50 es and a conserved hydrophobic region in the N-terminal portion of BovK sensor domain were important

51 n kinase domain and lacks the autoinhibitory N-terminal portion of BRAF.

52 monoclonal antibody we generated against the N-terminal portion of BRCA2.

53 -C/EBP-epsilon antibodies raised against the N-terminal portion of C/EBP-epsilon (amino acids 1 to 11

54 BPepsilon and fusion proteins containing the N-terminal portion of C/EBPepsilon, whereas PIASxalpha w

55 The complete HelX protein and the soluble N-terminal portion of Ccl2 (called Ccl2*) were overprodu

56 Herein, we show that the N-terminal portion of CNK (CNK(N-term)) strongly coopera

57 olypeptide of 24-25 kDa corresponding to the N-terminal portion of D1 that is unstable and appears to

58 The N-terminal portion of D2 is disordered, and this region

59 nd that mu1 autocleavage is regulated by the N-terminal portion of delta, which forms an alpha-helica

60 Mechanistic studies revealed that the N-terminal portion of Diaph1 interacted with both TbetaR

61 Like mammalian IRS proteins, the N-terminal portion of dIRS contains a pleckstrin homolog

62 ites are located in analogous regions of the N-terminal portion of each isozyme.

63 The N-terminal portion of ETO forms complexes with PLZF, whi

64 precursors demonstrated that the lack of the N-terminal portion of FE65, which includes part of the f

65 n-bond stabilised secondary structure in the N-terminal portion of fH module 16, and the number and t

66 by cell surface binding sites for the 70-kD N-terminal portion of fibronectin.

67 he frz genes as well as regions encoding the N-terminal portion of FrzCD.

68 around the fluorescein, suggesting that the N-terminal portion of galanin, which constitutes the bin

69 Thus, the N-terminal portion of GCLC may undergo a change that sta

70 MAbs (including H6 and 37S) reacted with the N-terminal portion of gH between amino acids 19 and 276.

71 a series of chimeric peptides combining the N-terminal portion of GLP-1 or Ex-4 and the C-terminal s

72 mbinant vaccinia viruses expressing only the N-terminal portion of gp160, containing P18 but not HP53

73 Several regions of the N-terminal portion of GroEL-bound mAAT are highly suscep

74 the STAT1 interaction domain resides in the N-terminal portion of HCV core (amino acids [aa] 1 to 23

75 oligomers in vitro and in vivo and that the N-terminal portion of HDAC3 is necessary for this proper

76 g site together with five differences in the N-terminal portion of helix I conferred S-mephenytoin 4'

77 1, the C-terminal portion of helix-2 and the N-terminal portion of helix-3, bounded by the intramolec

78 rkness, indicating that the COP1-interacting N-terminal portion of HFR1 is essential for COP1-mediate

79 This fragment interacts with the N-terminal portion of HIF-1alpha spanning amino acid res

80 the three-dimensional structure of a 22-kDa N-terminal portion of human eIF2alpha by x-ray diffracti

81 a protein shares sequencesimilarity with the N-terminal portion of human PCAF that is involved in bin

82 AT1aR replaced the HK of BKB2R, leaving the N-terminal portion of IC1 without a positively charged r

83 t two overlapping regions within the central N-terminal portion of ICP0 (residues 212 to 311) promote

84 n region I, termed Phos 1, which lies in the N-terminal portion of ICP0, impairs the E3 ubiquitin (Ub

85 Therefore, the N-terminal portion of ICP27 contains at least two functi

86 or binding to GC-rich sequences and that the N-terminal portion of ICP27 is highly flexible in struct

87 er, our results suggest a model in which the N-terminal portion of ICP27 mediates a nonessential acti

88 The N-terminal portion of ICP4 contains well-defined transac

89 is of IE1 regulatory domains, the M1 to T266 N-terminal portion of IE1 was subdivided (on the basis o

90 The proline-rich N-terminal portion of INSM1 is required for cyclin D1 bi

91 e describe a refined model of the alpha(IIb) N-terminal portion of integrin alpha(IIb)beta(3) obtaine

92 We determined that the N-terminal portion of IpaB is necessary for stable expre

93 s T-antigen binding was localized within the N-terminal portion of IRS-1 molecule, and the binding wa

94 lice variants which encode proteins with the N-terminal portion of K-bZIP but lacking the C-terminal

95 The N-terminal portion of K-bZIP is derived from the K8 open

96 In addition, we find that the N-terminal portion of Klar is also important for functio

97 Strains lacking only the N-terminal portion of L11 grew well at physiological tem

98 The lipid A-binding N-terminal portion of lactoferrin (residues 1-33) induce

99 erved amino acid residues indicated that the N-terminal portion of LasR is required for multimerizati

100 ate that a fusion protein of the ACD and the N-terminal portion of lethal factor from Bacillus anthra

101 ine a nuclear localization domain within the N-terminal portion of Lsh.

102 etween mixing and freezing, we find that the N-terminal portion of M13 converts from a conformational

103 d and positively charged residues within the N-terminal portion of MA constitute the membrane-binding

104 LS (FUS) and the related gene EWS encode the N-terminal portion of many fusion oncoproteins involved

105 o an unanticipated trans-acting role for the N-terminal portion of matrix in the formation of stable

106 110 kDa extracellular protein represents the N-terminal portion of mature Hap (designated Haps).

107 ex reveals that 3A6 primarily recognizes the N-terminal portion of MBP, in contrast with antimicrobia

108 Our data demonstrate that the N-terminal portion of MED12 wraps around CDK8, whereby i

109 A PB1 domain is encoded within the N-terminal portion of MEKK2, MEKK3, and MEK5.

110 d the interacting regions were mapped to the N-terminal portion of menin and amino acids 43 to 171 of

111 We report that the N-terminal portion of migfilin can bind all three human

112 One of these is the N-terminal portion of motif F and the second is a large

113 pha-beta FAD-binding motif is present in the N-terminal portion of mPAO.

114 The N-terminal portion of mPar3 exhibits strong microtubule

115 The N-terminal portion of NBD1 structure has an extra beta-s

116 ding motifs, or of the basic residues in the N-terminal portion of NC, abrogated assembly.

117 tion occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is

118 The N-terminal portion of NIL-16 interacts selectively with

119 The N-terminal portion of Notch(IC) inhibited p50 DNA bindin

120 izes to the nucleus and that a region in the N-terminal portion of Notch(IC), not the six ankyrin rep

121 rmal tissues, the two antibodies against the N-terminal portion of NPM labeled the cytoplasm of neopl

122 of which recognize, by Western blotting, the N-terminal portion of NPM present in the NPM-ALK fusion

123 sion domain (RepD1) to a small region at the N-terminal portion of NRIF3 (residues 20 to 50).

124 Protease p29, derived from the N-terminal portion of ORF A, functions as a suppressor o

125 encing, while protease p48, derived from the N-terminal portion of ORF B, is required for viral RNA r

126 The N-terminal portion of ORF9 was found to be similar to a

127 The p50 protein is incorporated within the N-terminal portion of p105 and is a unique product of pr

128 utant Cdc37 gene products indicated that the N-terminal portion of p50(cdc37) interacted with immatur

129 The N-terminal portion of p64 has several potential binding

130 The N-terminal portion of parathyroid hormone is critical fo

131 The N-terminal portion of PDE3 can be arbitrarily divided in

132 The N-terminal portion of phosphodiesterase (PDE) 3 was arbi

133 The N-terminal portion of PiTX-K alpha has three fewer resid

134 gests that TCR recognition is focused on the N-terminal portion of pMART-1.

135 An N-terminal portion of PP1G was cloned by RT-PCR, and dif

136 al assembly domain (the M domain) within the N-terminal portion of Pr55Gag mediates the interaction o

137 ing epitopes located within the unstructured N-terminal portion of PrP(C) and those recognizing epito

138 age and was localized to a region within the N-terminal portion of PspA.

139 overall data support the hypothesis that the N-terminal portion of PTH is alpha-helical when bound to

140 N-terminal cleavage fragment shows that the N-terminal portion of Rad9 localizes in the cytosol, bin

141 Since the N-terminal portion of RAD9p was previously demonstrated

142 Here we report that the N-terminal portion of RAG1 has a distinct enzymatic role

143 5 weakens the direct association between the N-terminal portion of RbC (RbC(N)) and the marked-box do

144 le proteolytic fragments accumulate from the N-terminal portion of RecE.

145 - or C-terminal deletions, we found that the N-terminal portion of RepA is required for recognition.

146 all of which are prenylated, as well as the N-terminal portion of retinitis pigmentosa GTPase regula

147 The N-terminal portion of Rhizobium FtsZ polymerized in Esch

148 The N-terminal portion of RP1 stimulates the formation of mi

149 ction with a 75-kD protein (p75) required an N-terminal portion of RPS2 that is smaller than the regi

150 Our data indicate that the N-terminal portion of RsiV from amino acid 1 to 60, whic

151 lowing cleavage by the unknown protease, the N-terminal portion of RsiV requires further processing,

152 ocation has 752 amino acids and contains the N-terminal portion of RUNX1 (also known as AML1, CBFalph

153 These observations suggest that the N-terminal portion of S(mu)bp-2 which encompasses severa

154 brid system, CCTeta was found to bind to the N-terminal portion of sGC.

155 have determined the crystal structure of the N-terminal portion of SHARPIN, which adopts the highly c

156 It is shown here that the N-terminal portion of sigma(E), residues 1-153, binds co

157 An N-terminal portion of Sir1 (residues 27 to 149 [Sir1(27-

158 The N-terminal portion of Sp110 was homologous to two previo

159 show that the coiled-coil region within the N-terminal portion of SS4 is involved in both processes.

160 Over-expression of the N-terminal portion of SSDP1 (N-SSDP1), which contains th

161 sphoesterase motif was identified within the N-terminal portion of Sts.

162 This analysis demonstrates that the N-terminal portion of TdT, including the BRCA-1 C-termin

163 The ASPL-TFE3 fusion replaces the N-terminal portion of TFE3 by the fused ASPL sequences,

164 ionic interactions was found to connect the N-terminal portion of the 8th helix to the nearby NPXXY

165 the endonuclease activity is mediated by the N-terminal portion of the A subunit.

166 The R- mutations were all located in the N-terminal portion of the A subunit.

167 D/H polymorphism at residue 216 falls in the N-terminal portion of the AAA+ domain near the sensor 1

168 y, WH2 shares structural similarity with the N-terminal portion of the actin monomer-sequestering thy

169 rypsin-resistant peptide did not include the N-terminal portion of the AhR against which the antibody

170 The N-terminal portion of the alpha subunit and the majority

171 rnal region of the donor which coded for the N-terminal portion of the alpha-lac gene.

172 t Anxa2 mediates HSC adhesion mainly via the N-terminal portion of the Anxa2 peptide.

173 ibe a small set of amino acid sites from the N-terminal portion of the basic helix-loop-helix (bHLH)

174 The most pronounced difference is in the N-terminal portion of the beta4-beta5 loop, which is str

175 The structure reveals that the N-terminal portion of the BPS region binds as a pseudosu

176 CBR inhibitors target a crevice between the N-terminal portion of the bridge helix and a surrounding

177 n appendage domain that is inserted into the N-terminal portion of the catalytic domain, and a C-term

178 nd sequence a PCR product that coded for the N-terminal portion of the CF-chitinase.

179 nt from Asn1 to Ala7 (denoted domain 1), the N-terminal portion of the collagen domain from Gly8 to G

180 gion or interchain disulfide linkage; 2) the N-terminal portion of the collagen-like domain is requir

181 o species, reveal that the EGF motif and the N-terminal portion of the cytoplasmic domain are importa

182 The proximal helix and the N-terminal portion of the distal helix are found to be i

183 Very slow NH exchange for the N-terminal portion of the distal helix suggest that an i

184 hydrophobic groove, which interacts with the N-terminal portion of the divergent IQ1 and IQ2 motifs.

185 genous protein that is highly related to the N-terminal portion of the FeLV envelope protein, which i

186 he CD44-binding site is localized within the N-terminal portion of the fibrin beta chains, including

187 CNS disease associated with the N-terminal portion of the Fr98 env gene was preceded by

188 p120, and molecular dynamics showed that the N-terminal portion of the fusion peptide can be solvent-

189 cell-cell fusion mechanism and show that the N-terminal portion of the gH cytotail is critical for th

190 op participates in communication between the N-terminal portion of the helicase and the C-terminal ca

191 Furthermore, an N-terminal portion of the herbicide resistance gene 5-en

192 uncated form of GGA1 (GGA1t) which lacks the N-terminal portion of the hinge domain in alpha(2B)-AR t

193 e papain-like protease p29, derived from the N-terminal portion of the hypovirus CHV1-EP713-encoded o

194 n M3R dimer that was cross-linked within the N-terminal portion of the i3 loop (264C) was functionall

195 This association involves the N-terminal portion of the intracellular tail of DAT and

196 Q2N antibodies, directed against a conserved N-terminal portion of the KCNQ2 polypeptide, to localize

197 These results indicate that the N-terminal portion of the large subunit of MBP contained

198 esidue 19, contribute to the capacity of the N-terminal portion of the ligand to interact with the ju

199 ecular effects on secondary structure in the N-terminal portion of the ligand.

200 The binding was further localized to the N-terminal portion of the M molecule.

201 gnated m2/m1) containing m2 sequences in the N-terminal portion of the m region was less potent in ca

202 The N-terminal portion of the M. catarrhalis acid phosphatas

203 uggest that the delta subunit N terminus and N-terminal portion of the M1 domain are, at least in par

204 respect to amino acid residue charge in the N-terminal portion of the mature protein has occurred re

205 H/DX protection, and only locally within the N-terminal portion of the MBD.

206 we determined the solution structure of the N-terminal portion of the MCM complex from the archaeon

207 contact between Cdc6 and MCM occurs via the N-terminal portion of the MCM protein.

208 ect ovarian Sf9 cells induced to express the N-terminal portion of the molecule form MT-rich processe

209 nic interactions, localized primarily in the N-terminal portion of the molecule, enhance the stabilit

210 pterin aldolase function is expressed as the N-terminal portion of the multifunctional folic acid syn

211 of the Rel homology domain (RHD) within the N-terminal portion of the NF-kappa B 1 protein is requir

212 , which normally generates p50, degrades the N-terminal portion of the NF-kappa B 1 protein when the

213 Itch binds to the N-terminal portion of the Notch intracellular domain via

214 encode one methyltransferase, located at the N-terminal portion of the NS5 protein, to catalyze both

215 st two-hybrid system indicated that only the N-terminal portion of the p-55 domain is required for p-

216 All lack the N-terminal portion of the p21 core.

217 , in which the Bpa residue is located in the N-terminal portion of the peptide, was used to define fu

218 rther assess the functional relevance of the N-terminal portion of the perforin molecule in its lytic

219 These results suggest the N-terminal portion of the perforin molecule to be an imp

220 Even more unusually, the N-terminal portion of the polypeptide chain is pinned to

221 in of the scaffolding subunit resides in the N-terminal portion of the polypeptide chain.

222 38), Cys(48), Cys(70), and Cys(72)] with the N-terminal portion of the potyvirus-encoded helper compo

223 Post-translational processing of the N-terminal portion of the predicted gene product to give

224 om the membrane bilayer, suggesting that the N-terminal portion of the presequence is essential for m

225 ation of a fusion protein (PF-MC) made up of N-terminal portion of the protease inhibitor Trappin-2 (

226 onstrate that despite massive changes in the N-terminal portion of the protein and in the DNA upstrea

227 The presence of the N-terminal portion of the protein appeared to promote at

228 eral SHANK3 missense mutations affecting the N-terminal portion of the protein by expression of wild-

229 The N-terminal portion of the protein is important for inter

230 region of Rgt1 physically interacts with the N-terminal portion of the protein that includes the DNA-

231 IcmR was found to bind to the N-terminal portion of the protein thus providing a mecha

232 gnal and was secreted by the T4SS, while the N-terminal portion of the protein was not secreted.

233 n Methanothermobacter thermautotrophicus the N-terminal portion of the protein was shown to be involv

234 requires the Acidic blob (AB) region in the N-terminal portion of the protein, indicating that the A

235 on sites of ICP27 appeared to cluster in the N-terminal portion of the protein, such that a frameshif

236 Some of these mutations occur in the N-terminal portion of the protein, the Mad homology 1 (M

237 r the archaeal protein it was shown that the N-terminal portion of the protein, which is composed of

238 , but also present within the poorly defined N-terminal portion of the protein.

239 e for the non-functional segment at the most N-terminal portion of the protein.

240 closely spaced transmembrane domains in the N-terminal portion of the protein.

241 The N-terminal portion of the PstDNV coat protein adopts a "

242 The results demonstrate that the N-terminal portion of the PTHrP molecule is responsible

243 nist, a synthetic lipopeptide comprising the N-terminal portion of the putative Mycobacterium leprae

244 The N-terminal portion of the putative protein product prese

245 ve genitotropic serovars possessed an intact N-terminal portion of the putative toxin gene.

246 ently developed a shortened CFTR missing the N-terminal portion of the R domain (residues 708-759, CF

247 on interaction with vitronectin, whereas the N-terminal portion of the reactive loop does not experie

248 ased on TREM2 and TYROBP fusion to the C- or N-terminal portion of the Renilla luciferase gene.

249 8)] is further divided into N-terminal [RS1: N-terminal portion of the RS domain (residues 198-227)]

250 RPK1 has been shown to polyphosphorylate the N-terminal portion of the RS domain (RS1) of the SR prot

251 of approximately a dozen serines in only the N-terminal portion of the RS domain (RS1).

252 ion of a short stretch of amino acids in the N-terminal portion of the RS domain of ASF/SF2 while Clk

253 The N-terminal portion of the seatbelt contains a small disu

254 ct E36 cells, whereas vectors containing the N-terminal portion of the SSAV SU protein and C-terminal

255 transmembrane domain 5 (TM5) and within the N-terminal portion of the third intracellular loop (i3 l

256 The N-terminal portion of the Toc75 transit peptide is suffi

257 The Wld(s) protein consists of the N-terminal portion of the ubiquitination factor Ube4b fu

258 es and limited proteolysis revealed that the N-terminal portion of the unassembled subunit is meta-st

259 raised against a repetitive sequence in the N-terminal portion of the WND molecule detects an additi

260 breakdown was inhibited by TIMP-1 or by the N-terminal portion of TIMP-3, although FGF-2 did not aff

261 ) binds to ssRNA, our studies imply that the N-terminal portion of TLR7 triggers a yet to be identifi

262 e compatible with involvement in vivo of the N-terminal portion of troponin I in enhancing force prod

263 1 and a CD36 agonist antibody but not by the N-terminal portion of TSP1, suggesting that CD36 or a re

264 howed that the complete TUSP protein and the N-terminal portion of TUSP are localized in the cytoplas

265 either the C-terminal portion of UCR1 or the N-terminal portion of UCR2 abolishes dimerization of PDE

266 coimmunoprecipitation assay to show that the N-terminal portion of UL9 can indeed directly interact w

267 teract via their C-terminal domains with the N-terminal portion of UPL3.

268 formation is contained within the cytosolic, N-terminal portion of V-ATPase subunit a (Stv1p).

269 SU, amino acids 83 to 116, encompassing the N-terminal portion of variable region A (VRA).

270 Here, the degree of motion in the N-terminal portion of Vik1 highly correlated with that i

271 The N-terminal portion of WAX2 is homologous with members of

272 Because the N-terminal portion of Wld(S) (N70) localized to axons, w

273 A small region in the N-terminal portion of xSLBP1 is required to stimulate tr

274 t a characterization of the structure of the N-terminal portion of yeast Sac1, containing the conserv

275 A interaction are mapped, revealing that the N-terminal portion of YY1 (amino acids 1-300) and the DN

276 Therefore, the N-terminal portion of Zcchc11, which lacks nucleotidyltr

277 e yeast two-hybrid system indicates that the N-terminal portions of cotton fiber GhCesA1 and GhCesA2

278 Taken together, these results identify N-terminal portions of FGF8 protein isoform for having t

279 Kinetic and NMR studies thus reveal that the N-terminal portions of FXIII AP (28-37) (V34 and V34L) a

280 The N-terminal portions of HAP form a beta-strand that inser

281 When coupled to microspheres, N-terminal portions of human A beta (A beta 1-16, A beta

282 teristic of much of the protection-eliciting N-terminal portions of PspA and PspC.

283 thetic peptides encompassing the central and N-terminal portions of the alpha1 chain.

284 Considering that the N-terminal portions of the core histones constitute site

285 en fluorescent protein (GFP)- or FLAG-tagged N-terminal portions of the Htt protein containing either

286 S. pneumoniae ClpXP in vivo, even though the N-terminal portions of the tags differ significantly bet

287 -helix crosses the OM first, followed by the N-terminal portions of the virulence protein.

288 Little similarity is present in the N-terminal portions of these peptides, which might sugge

289 ll-down assay suggests an association of the N-terminal portion (Phe(120)-Phe(187)) of the D2 loop wi

290 The N-terminal portion, PTHrP-(1-34), retains all the calcio

291 onal roles have not yet been assigned to the N-terminal portion (residues 1-491; XPC-N).

292 o the register of the heptad repeat from the N-terminal portion (S1 path) of the molecule.

293 We investigated the role of the N-terminal portion (SS1) of the S5-S6 linkers in channel

294 r membrane protein with a long extracellular N-terminal portion that bears several ligand-binding dom

295 hatase activity and a proteolytically labile N-terminal portion that functions to enhance the affinit

296 In contrast to the soluble N-terminal portion, the C-terminal tyrosine-rich fragmen

297 by proteins with distinct homology in their N-terminal portion to bacterial Type IV pilins.

298 partite architecture consisting of a soluble N-terminal portion (TprC(N)), presumably periplasmic and

299 gnal peptides, were identical; the remaining N-terminal portions were gene specific.

300 zed by a conserved tripartite motif in their N-terminal portion which comprises a canonical RING doma