ライフサイエンスコーパス: NAT

1 NAT for gastrointestinal cancers results in overall lowe

2 NAT gene regions also exhibit higher levels of H3K36me3,

3 NAT patients were more likely to be downstaged (39.9% vs

4 NAT screening has emerged as the preferred option for de

5 NAT was measured at the level of the C5 vertebral body,

6 NAT(+) samples were confirmed by real-time polymerase ch

7 We also show that N-oleoyl taurine (C18:1 NAT), the most abundant NAT in human plasma, decreases f

8 To date, 12 NATs have been identified, harboring different compositi

9 ngular nanoprisms and 2-naphthalenethiols (2-NAT) as a prototypical system, we show that the preferen

10 e show that the preferential adsorption of 2-NAT on the prism tips leads to formation of tip patches.

11 d to a reuleaux triangle by increasing the 2-NAT-to-prism concentration ratio.

12 lantation with HCV-positive donor hearts (20 NAT-positive, five NAT-negative), three of whom underwen

13 acetylation and internal modifications in a NAT substrate-specific manner.

14 ORE), a circadian-regulated lncRNA that is a NAT of CDF5.

15 tion at convergent loci is also found when a NAT to hygromycin resistance gene is driven off the endo

16 leoyl taurine (C18:1 NAT), the most abundant NAT in human plasma, decreases food intake, improves glu

17 homologous to arylamine N-acetyltransferase (NAT) and has been identified in Fusarium infecting cerea

18 unconventional N-terminal acetyltransferase (NAT) because it localizes to organelles, in particular t

19 of three major N-terminal acetyltransferase (NAT) complexes (NatA-NatC), which co-translationally ace

20 mutation in an N-terminal acetyltransferase (NAT) gene.

21 Human N-acetyltransferases (NAT; EC 2.3.1.5) catalyze the N-acetylation of arylamine

22 y a family of N-terminal acetyltransferases (NAT).

23 activity of arylamine N-acetyltransferases (NATs) in excised liver samples was examined using eighte

24 Arylamine N-acetyltransferases (NATs), a class of xenobiotic-metabolizing enzymes, catal

25 roteins is modified by N-acetyltransferases (NATs).

26 arried out by N-terminal acetyltransferases (NATs), is a conserved and primary modification of nascen

27 ukaryotic amino-terminal acetyltransferases (NATs), which are differentiated from one another on the

28 nzymes called N-terminal acetyltransferases (NATs).

29 ut by six amino-terminal acetyltransferases (NATs).

30 biotics is powered by the N-acyltransferase (NAT) Orf11*/Dbv8 through N-acylation on glucosamine at t

31 st was followed <6 months by >/=1 additional NAT(s), or ALT, AST, and platelets <90 days, or any test

32 ic performance of ART in PDAC resected after NAT.

33 All NATs contain at least one catalytic subunit, and some co

34 rong interaction between water ice and alpha-NAT was found, which explains the experimental spectra a

35 d phase, alpha-nitric acid trihydrate (alpha-NAT), is presented.

36 nalyses reveal altered pathways shared among NATs across tissue types.

37 hat modifies CobB(L), and 3) that YiaC is an NAT.

38 es and is believed to represent an ancestral NAT variant from which the eukaryotic NAT machinery evol

39 entrations of COT, COT-OH, ANATA, ANABA, and NAT were 5200, 2600, 30, 10, and 0.6 ng/L, respectively,

40 in this period were observed between DOX and NAT (33.10%) and DOX and BC (32.43%).

41 al differences were observed between DOX and NAT (34.61%) and DOX and BC (23.11%).

42 Much more lincRNA and NAT genes were derived from conserved genomic regions be

43 revealed a distinct clustering of tumor and NAT microbiota in both BNH and WNH cohorts.

44 problem of concurrent elevation of NAEs and NATs caused by genetic or pharmacological disruption of

45 d the X-ray crystal structure of an archaeal NAT from Sulfolobus solfataricus (ssNAT).

46 active and to acetylate prototypic arylamine NAT substrates.

47 However, a putative atypical NAT harboring a catalytic triad Glu residue was recently

48 l origin, as well as instances in which both NAT tissue and tumor tissue harbor a gain of the same on

49 VAb testing in fingerstick blood followed by NAT in venipuncture blood yields relatively lower viremi

50 VAb testing in fingerstick blood followed by NAT in venipuncture blood.

51 sense and antisense transcripts produced by NAT pairs is significantly correlated, particularly unde

52 rstanding the mode of substrate selection by NAT enzymes.

53 cis-NAT-derived siRNAs (nat-siRNAs) are present in plants, a

54 We found 209 cis-NAT pairs that have opposite expression levels in neighb

55 We found that a cis-NAT positively regulates the level of a protein critical

56 -NAT pairs and identified 918 additional cis-NAT pairs.

57 is-NATs, suggesting a connection between cis-NAT transcription and chromatin modification in plants.

58 Compared with other genes, cis-NAT-encoding genes have enriched low-nucleosome-density

59 Newly identified cis-NAT pairs are supported by polyadenylation data, alterna

60 is libraries confirmed most of the known cis-NAT pairs and identified 918 additional cis-NAT pairs.

61 expression in protoplasts, the impact of cis-NAT expression on mRNA translation was confirmed for 4 o

62 ing data showed that approximately 4% of cis-NAT pairs produce putative cis-NAT-induced siRNAs.

63 With use of a combination of cis-NAT stable over-expression in transgenic plants and tran

64 found in the 5' regulatory sequences of cis-NAT-encoding genes.

65 We also broadly extend annotations of cis-NAT-siRNA loci, identifying ones with common expression

66 ely 4% of cis-NAT pairs produce putative cis-NAT-induced siRNAs.

67 tion was confirmed for 4 out of 5 tested cis-NAT:sense mRNA pairs.

68 tments) allowed the identification of 14 cis-NATs whose expression correlated either positively or ne

69 s (Arabidopsis thaliana), protein-coding cis-NATs are also characterized by high abundance, high coex

70 ations of new technologies for detecting cis-NATs, including direct RNA sequencing and strand-specifi

71 as designed to systematically search for cis-NATs influencing cognate sense mRNA translation in Arabi

72 s, implying cell-type-specific roles for cis-NATs.

73 ural antisense small RNA production from cis-NATs is limited.

74 NATs and 19%-29% of the siRNA-generating cis-NATs in plants give rise to siRNAs only in their overlap

75 To identify cis-NATs using ssRNA-seq, we developed a new computational m

76 their cognate sense gene are known, most cis-NATs function by altering the steady-state level or stru

77 of siRNAs in the overlapping regions of cis-NATs and 19%-29% of the siRNA-generating cis-NATs in pla

78 These results expand the number of cis-NATs known to regulate cognate sense mRNA translation an

79 Whereas several examples of cis-NATs regulating the expression of their cognate sense ge

80 entified a unique chromatin signature of cis-NATs, suggesting a connection between cis-NAT transcript

81 r multifaceted regulatory roles of plant cis-NATs.

82 sms for regulating the expression of the cis-NATs.

83 luding dcl1, dcl2, dcl3, and rdr6 map to cis-NATs as frequently as small RNAs sequenced from wild-typ

84 cis-natural antisense transcripts (cis-NATs) are widespread in plants and are often associated

85 alled cis-natural antisense transcripts (cis-NATs), and they play key roles in the regulation of gene

86 Cis-Natural Antisense Transcripts (cis-NATs), which overlap protein coding genes and are transc

87 cis-natural sense antisense transcripts (cis-NATs).

88 ved: BC (untreated, filled with blood clot), NAT (natrosol gel alone), and DOX (10% doxycycline gel).

89 te congenital infection and surveillance CMV NAT at 5 additional intervals between birth and 90 days,

90 The infants underwent serum and urine CMV NAT at birth to evaluate congenital infection and survei

91 We compared NAT compartments across lean, overweight, and obese grou

92 Conclusion NAT followed by resection has a significant survival ben

93 d multivariate regression models correlating NAT with CVD risk factors.

94 effects on 626 concordant and 766 discordant NAT pairs.

95 We show that the newly discovered NAT negatively regulates Nos1 gene expression.

96 on in FAAH (S268D) that selectively disrupts NAT, but not NAE, hydrolytic activity.

97 w projections of dengue incidence from donor NAT yield data and vice versa, and suggest that viremic

98 implications for the evolution of eukaryotic NAT enzymes and the substrate specificities therein.

99 estral NAT variant from which the eukaryotic NAT machinery evolved.

100 To date, two eukaryotic NATs, NatA and NatE, have been structurally characterize

101 Finally, NAT pairs in 368 diverse maize inbreds and 19 segregatin

102 positive donor hearts (20 NAT-positive, five NAT-negative), three of whom underwent simultaneous hear

103 We propose that the CDF5/FLORE NAT pair constitutes an additional circadian regulatory

104 loying a rapid, point-of-care assay) and for NAT (whether done by reflex or using separately drawn bl

105 in order to decipher the molecular basis for NAT's functionality.

106 s, we propose a new three-step mechanism for NAT formation in high-altitude ice clouds.

107 sociated factor as a potential repressor for NAT abundance.

108 gy requiring the tested person to return for NAT.

109 The strategy that requires returning for NAT is even less viremia sensitive (<0.9000) because of

110 sive account of NATs and supports a role for NATs' regulation of tumor suppressors and oncogenes in c

111 he response to the natural external forcing (NAT) in the two-signal analysis.

112 The lessons from NAT are translatable to clinical oncology and may help t

113 d are similar to those present in functional NATs.

114 ing OncoNAT we identified several functional NATs, including NKX2-1-AS1 that regulates the NKX2-1 onc

115 We propose that fungal NAT isoenzymes may have evolved to perform diverse funct

116 Further, NATs are significantly hypomethylated and include fewer

117 rticipants recommended that HIV, HBV and HCV NAT should not be required for live donor evaluation; th

118 OPOs performed prospective HIV, HBV and HCV NAT, respectively.

119 mediated amplification assay for HIV and HCV NAT, respectively.

120 IV NAT and 55 respondents that performed HCV NAT, 39 tested all donors.

121 ntly infected" if they had >/=1 positive HCV NAT; "in care" if a positive RNA test was followed <6 mo

122 ively analyze the transcriptomes of healthy, NAT, and tumor tissues in 6506 samples across eight tiss

123 ingly, co-depletion of NatA, a heterodimeric NAT complex that physically interacts with Naa50, rescue

124 Of the 56 respondents that performed HIV NAT and 55 respondents that performed HCV NAT, 39 tested

125 nin tautomers and radical species into human NAT crystal structures supported the hypothesis that thi

126 e catalytic subunit of NatA, the major human NAT involved in the co-translational acetylation of prot

127 The involvement of human NAT enzymes in different pathological conditions, such a

128 The resulting HXT-NAT reporter strains exhibited a strict growth dependenc

129 AT, universal mini-pool NAT (MP-NAT), and ID-NAT exclusively for components transfused to women of ch

130 individual donation nucleic acid testing (ID-NAT) of donated blood for Zika virus began in U.S. state

131 Universal ID-NAT cost $341 million per QALY (CI, $125 million to $2.9

132 Universal ID-NAT, universal mini-pool NAT (MP-NAT), and ID-NAT exclus

133 0 (also named NatF) is a recently identified NAT found only in multicellular eukaryotes.

134 serology negative donors to 70.8% (17/24) if NAT was available and the donor had no increased activit

135 espondents were more likely to accept IRD if NAT was available.

136 Thus, many of our processes are, in NAT terms, interactively complex and tightly coupled wit

137 the hypothesis that thiol functionalities in NAT enzymes may be crucial in apocynin binding.

138 18 genes that are specifically activated in NATs.

139 al exposure signatures and a field effect in NATs.

140 e accordingly show substantial elevations in NATs without alterations in NAE content, a unique metabo

141 cies was at least as effective in increasing NAT activity as seen with control nerves.

142 Expression of the spliced form of LEF1 NAT in trans prevents the action of unspliced NAT by com

143 Unspliced LEF1 NAT interacts with LEF1 promoter and facilitates PRC2 bi

144 cant (p < 0.001) reduction of in vitro liver NAT activity up to 93% as compared with untreated rats (

145 the opposite strand of a coding gene locus, NATs are proving to be a heterogeneous group with high p

146 Here we investigated a long NAT (antiNOS-2 RNA) associated with the regulation of ni

147 Here we report that a long NAT (Mm-antiNos1 RNA) complementary to mRNA encoding the

148 Although recent studies indicate that long NATs are engaged in the regulation of gene expression, t

149 ted the functional expression of a mammalian NAT in Aspergillus nidulans Thus, our results provide a

150 NBC tumor tissue was compared to the matched NAT.

151 BNH TNBC tumor tissue as compared to matched NAT zone.

152 Matched NATs allowed identification of differentially expressed

153 niversal ID-NAT, universal mini-pool NAT (MP-NAT), and ID-NAT exclusively for components transfused t

154 In Puerto Rico, MP-NAT exclusively during high mosquito season was cost-eff

155 In Puerto Rico, MP-NAT only during the season of high mosquito activity was

156 s is silent in epithelial cells, and neither NAT transcript nor LEF1 mRNA are expressed, in cell line

157 -nitrosoanabasine (NAB), N-nitrosoanatabine (NAT), N-nitrosonornicotine (NNN), 4-(methylnitrosamino)-

158 the CSTs were crushed bilaterally, nocturnal NAT was decreased by 99%.

159 ansposable element sequences relative to non-NAT genes.

160 ly higher proportion of NATs relative to non-NATs are specifically expressed under water stress (WS).

161 information necessary for directing a normal NAT rhythm and thus normal pineal function.

162 eporter strains in which the nourseothricin (NAT) resistance gene is expressed under the control of t

163 udy, we identified and characterized a novel NAT, AS-IL1alpha, which is partially complementary to IL

164 ecent structural and biochemical analysis of NAT proteins allows for a comparison of their molecular

165 were performed to examine the association of NAT compartments with metabolic syndrome.

166 The results suggest that availability of NAT would increase IRD utilization.

167 th Carolina, we have applied the concepts of NAT to our practice to better understand our systems' be

168 we investigate functional diversification of NAT enzymes in crop-compromising species of Fusarium and

169 logy (NAT) yield to estimate the duration of NAT-detectable viremia and compared with reported clinic

170 To gain insight into the evolution of NAT enzymes, we determined the X-ray crystal structure o

171 ocynin led to a dose-dependent inhibition of NAT activity with IC50 = 0.69 +/- 0.02 mM.

172 is known about the transcriptomic profile of NAT, how it is influenced by the tumor, and how the prof

173 The five recipients of NAT-negative grafts did not become viraemic.

174 All 20 recipients of NAT-positive hearts tolerated glecaprevir-pibrentasvir a

175 histone modifications have in regulation of NAT expression, and the significance of NATs in response

176 A set of NAT genes also showed expression correlation with their

177 These findings support the use of NAT, particularly as a patient selection tool, in the ma

178 With increasing use of NAT, this brings into question the validity of quality m

179 is study provides a comprehensive account of NATs and supports a role for NATs' regulation of tumor s

180 with light-responsive expression changes of NATs.

181 further study of the evolutionary history of NATs and the functional significance of the predominant

182 nificance of the subcellular localization of NATs and their biological functions remain to be defined

183 A significantly higher proportion of NATs relative to non-NATs are specifically expressed und

184 We found an unexpected large proportion of NATs with protein coding potential, as estimated by ribo

185 tion of cognate sense genes, and the role of NATs in cancer remain poorly understood.

186 To understand the role of NATs in the clock, we put the frq antisense transcript q

187 n of NAT expression, and the significance of NATs in response to WS.

188 The functional significance of NATs is poorly understood, but their prevalence in the C

189 Although thousands of NATs are encoded by mammalian genomes, their functions i

190 his modification is less prevalent, only one NAT enzyme has been identified.

191 or NAT (n = 87; P = 0.003); N+ without VR or NAT (n = 50; P = 0.004).

192 atectomy (n = 117; P = 0.049); without VR or NAT (n = 87; P = 0.003); N+ without VR or NAT (n = 50; P

193 enotypes are caused by elevations in NAEs or NATs is unknown.

194 d 1769 sense and antisense transcript pairs (NAT pairs) in two maize inbreds with different sensitivi

195 und evidence for cytoplasmically partitioned NATs.

196 Since 2008, the number of OPOs performing NAT has increased and more OPOs are testing all donors.

197 es, and in high-incidence regions performing NAT.

198 a considerable promise for low-cost and POC NAT in remote areas.

199 Universal ID-NAT, universal mini-pool NAT (MP-NAT), and ID-NAT exclusively for components tran

200 ethod to predict patient outcomes after post NAT resection across various cancer types.

201 ethod to predict patient outcomes after post NAT resection in various cancer types.

202 Sixty-three patients with PDAC after post NAT resection were analyzed.

203 %, all strategies when adopting quantitative NAT vary little in cost (range, $29.50-$30.70) and are h

204 of-care assay, when followed by quantitative NAT done reflexively or in separately drawn blood, are c

205 dopting qualitative rather than quantitative NAT are slightly cheaper (range, $28.90-$29.99), similar

206 Only Cs- and Rb-NAT reveal a phase separation into a dense form (P2 phas

207 ed of which 61.1%, 21.2%, and 85.7% received NAT, respectively.

208 The results point to FAAH-regulated NAT signaling as an unprecedented lipid-based mechanism

209 3000 IU/mL and have the potential to replace NAT in settings with high HCV prevalence.

210 s for a large number of the light-responsive NAT pairs are associated with histone modification peaks

211 ybrid methods, revealed that salt responsive NAT-related lncRNAs associated with transcription factor

212 nt NatA and Naa50 do not affect each other's NAT activity in vitro Because NatA and Naa50 exhibit dis

213 tegies, we identify two long-chain saturated NATs-N-tetracosanoyl-taurine [NAT(24:0)] and N-eicosanoy

214 od to assess metabolic risk, cross-sectional NAT assessment provides further insight into fat accumul

215 r, has encouraged the research for selective NAT inhibitors in both humans and animal models with pos

216 iptome analysis of 10 genes that make up six NATs in humans from eight different cell lines suggests

217 cost, user-friendly, sensitive, and specific NAT platform with great potential in point-of-care diagn

218 Contrarily to the spliced NAT, this unspliced NAT down-regulates the main LEF1 pro

219 bility of an adrenergic agonist to stimulate NAT activity was reduced in rats with regenerated CSTs.

220 Most strikingly, NAT can catalyze formation of 2-N,6-O-diacylated or C6--

221 trate that local administration of synthetic NATs accelerates wound closure in mice and stimulates re

222 aurine [NAT(24:0)] and N-eicosanoyl-taurine [NAT(20:0)]-as primary substrates for FAAH in mouse skin,

223 hain saturated NATs-N-tetracosanoyl-taurine [NAT(24:0)] and N-eicosanoyl-taurine [NAT(20:0)]-as prima

224 cylethanolamines (NAEs) and N-acyl taurines (NATs), in central and peripheral tissues.

225 n fatty acids with taurine [N-acyl-taurines (NATs)].

226 on of nucleic acid-amplification technology (NAT) screening for HIV, HCV, and HBV has reduced the res

227 ve to nucleic acid amplification technology (NAT) yield to estimate the duration of NAT-detectable vi

228 ody (HCVAb) followed by a nucleic acid test (NAT) for HCV RNA when the antibody test is positive, are

229 Although the majority of tested NATs were found to localize to the nucleus, we also foun

230 cy requires the use of nucleic acid testing (NAT) for organ donor screening.

231 Cytomegalovirus nucleic acid testing (NAT) of transfused blood components and breast milk was

232 sing a high-throughput nucleic acid testing (NAT) platform.

233 NGS) with confirmatory nucleic acid testing (NAT) to routine clinical diagnostic testing in detection

234 ) had access to timely nucleic acid testing (NAT), and respondents were more likely to accept IRD if

235 eart, as determined by nucleic acid testing (NAT), received pre-emptive oral glecaprevir-pibrentasvir

236 creen and confirmatory nucleic acid testing (NAT).

237 l use of nucleic acid amplification testing (NAT) for the screening of potential organ donors should

238 ositive as measured by nucleic acid testing [NAT]).

239 ther point-of-care (POC) nucleic acid tests (NAT), MTNT could assay both DNA and RNA directly from li

240 , HCV RNA, HCV genotype (nucleic acid tests [NAT]), liver function tests, and platelet counts; patien

241 antigen may become more cost-effective than NAT for the screening of potential organ donors.

242 We hypothesize that NAT decreases LN metastasis, downstages patients, and de

243 ut lower levels of H3K27me3, indicating that NAT gene pairs generally exhibit an open chromatin confi

244 Our analysis shows that NAT presents a unique intermediate state between healthy

245 Together, these data suggest that NATs act as a class of lipid messengers that improve pos

246 The NAT enzyme possesses enormous value in untapped applicat

247 The NAT group was associated with improved survival compared

248 henotype presenting low LEF1 expression, the NAT is synthesized and remains unprocessed.

249 or VR; (2) R1-0 mm posterior-margin for the NAT group (P = 0.004).

250 From the NAT group, 2,005 patients (95%) were matched with 6,015

251 We document matching sCNAs in the NAT tissue and the adjacent tumor, suggesting a shared c

252 rtebrates (e.g. fish) and mammals, where the NAT gene is selectively expressed in noradrenergic cells

253 most of the observed PW increase, while the NAT forcing leads to small moistening.

254 The physiological functions of the NATs are unknown.

255 ower), concepts from Normal Accident Theory (NAT), a framework for analyzing failure potential within

256 n patients who received neoadjuvant therapy (NAT) followed by resection and those who received upfron

257 dergone resection after neoadjuvant therapy (NAT).

258 f UR patients who received adjuvant therapy, NAT patients had a better survival (adjusted hazard rati

259 by an antisense non-coding RNA and that this NAT function is regulated by the balance between its spl

260 ith the hypothesis that neck adipose tissue (NAT) accumulation preferentially involves specific compa

261 bjective was to measure neck adipose tissue (NAT) compartments and examine relations with CVD risk ma

262 ors and 101 matched normal adjacent tissues (NATs) incorporating genomics, epigenomics, deep-scale pr

263 tigen (HCVcAg) is a potential alternative to NAT.

264 A natural antisense transcript (NAT) is transcribed from a promoter present in the first

265 requency (frq) natural antisense transcript (NAT) qrf.

266 by acting as a natural antisense transcript (NAT) that regulates the neuronal mRNA levels of seizure

267 s of sense and natural antisense transcript (NAT).

268 Natural antisense transcripts (NATs) are a class of long noncoding RNAs (lncRNAs) that

269 Natural antisense transcripts (NATs) are a prominent and complex class of regulatory RN

270 Natural antisense transcripts (NATs) are endogenous RNA molecules that are complementar

271 ese so-called natural antisense transcripts (NATs) are possibly co-regulated.

272 ng non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species.

273 tory roles of natural antisense transcripts (NATs) arising from what was previously thought to be 'ju

274 scovered that natural antisense transcripts (NATs) frequently have actively translated sORFs, includi

275 production of natural antisense transcripts (NATs) in the context of actively expressed genes.

276 ong noncoding natural antisense transcripts (NATs) originate from Period in mammals and frequency (fr

277 NAs) that are natural antisense transcripts (NATs) to transcripts encoding central oscillator compone

278 he extent of natural antisense transcripts' (NATs) expression, their regulation of cognate sense gene

279 The 20th Nantes Actualites Transplantation (NAT) meeting was held on June 11, 2015, and June 12, 201

280 ber of the nucleobase/ascorbate transporter (NAT) family of proteins, and is responsible for the prot

281 ubiquitous nucleobase ascorbate transporter (NAT) family.

282 expression of the noradrenaline transporter (NAT) gene, and not the serotonin transporter genes, in d

283 oblastoma and UVW/noradrenaline transporter (NAT) glioma cells.

284 rty patients received neoadjuvant treatment (NAT = 20%); 41 had venous resection (VR = 28%), and 70%

285 gically normal tissue adjacent to the tumor (NAT) is commonly used as a control in cancer studies.

286 and matched normal tissue adjacent to tumor (NAT) samples collected from Black non-Hispanic (BNH) and

287 in 1,708 normal-appearing adjacent-to-tumor (NAT) tissue samples from 27 cancer sites and in 7,149 bl

288 Interestingly, these two NATs use different catalytic strategies to accomplish su

289 As all patients undergoing NAT receive multimodality therapy, LN yield recommendati

290 Patients who underwent NAT followed by curative-intent resection were matched b

291 AT in trans prevents the action of unspliced NAT by competing for interaction with the promoter.

292 ontrarily to the spliced NAT, this unspliced NAT down-regulates the main LEF1 promoter activity and a

293 al CMV infection, detected by serum or urine NAT.

294 mediate substrate-specific activity, and use NAT-type specific auxiliary and regulatory subunits, for

295 cancers are increasingly being treated with NAT before surgical resection.

296 Small RNAs significantly accumulate within NAT pairs, with 21 nt smRNA particularly enriched in ove

297 N0 patients without NAT, N+ patients without NAT or VR; (2) R1-0 mm posterior-margin for the NAT grou

298 (upfront pancreatectomy, N0 patients without NAT, N+ patients without NAT or VR; (2) R1-0 mm posterio

299 ted total LNY and LN metastasis with/without NAT and clinical and pathological stage to evaluate rate

300 2010-2015) treated with surgery with/without NAT were identified in National Cancer Database.