ライフサイエンスコーパス: NMR method

1 solved by a hybrid solution and solid-state NMR method.

2 16-mer consensus DNA using multidimensional NMR method.

3 the rotational echo double resonance (REDOR) NMR method.

4 coordinate accuracy within the limits of the NMR method.

5 asured with the (1) H-observed/(13) C-edited NMR method.

6 ent vineyards were determined using the SNIF-NMR method.

7 ned from the pulse gradient spin echo (PGSE) NMR method.

8 pplied advanced multidimensional solid-state NMR methods.

9 o hours and allows their characterization by NMR methods.

10 sparsely populated to observe by traditional NMR methods.

11 lide structures were determined by 1D and 2D NMR methods.

12 rough analysis of the signals with 1D and 2D NMR methods.

13 multiprotein complexes using solution-state NMR methods.

14 l (1)H-(1)H correlated and (1)H-(13)C-edited NMR methods.

15 nalysis as well as directly through multiple NMR methods.

16 domain of FIP2 in the absence of Rab11 using NMR methods.

17 rystallography and of a larger M2 peptide by NMR methods.

18 ermined by both x-ray crystallography and by NMR methods.

19 s with quinuclidine bases were determined by NMR methods.

20 , fluorescence, and high-resolution solution NMR methods.

21 nd joining (NHEJ), has been determined using NMR methods.

22 s well as two-dimensional 13C-1H correlative NMR methods.

23 respectively, which can be characterized by NMR methods.

24 active site of ARD' inaccessible to standard NMR methods.

25 ture of apo NosL has been solved by solution NMR methods.

26 d the backbone dynamics by multi-dimensional NMR methods.

27 o BIV TAR RNA determined using heteronuclear NMR methods.

28 blished using mass spectrometry and multiple NMR methods.

29 DDFT)-electronic circular dichroism, and DFT-NMR methods.

30 axation optimized spectroscopy (TROSY)-based NMR methods.

31 to enhance aqueous solubility) with SecA by NMR methods.

32 ligomers was confirmed via 1D and 2D (NOESY) NMR methods.

33 design of (1)H, (15)N, or (13)C solid-state NMR methods.

34 the engineered protein with multidimensional NMR methods.

35 ss were determined through conventional (1)H NMR methods.

36 rain 385-99 (WN-rED3) has been determined by NMR methods.

37 structure of human SWI1 ARID using solution NMR methods.

38 have been investigated with high-resolution NMR methods.

39 and determined high-resolution structures by NMR methods.

40 lts along with two-dimensional heteronuclear NMR methods.

41 guests in a cylindrical host was studied by NMR methods.

42 means of conventional and new field-cycling NMR methods.

43 een determined in solution though the use of NMR methods.

44 phospholipid bicelles using high-resolution NMR methods.

45 hia coli under resting conditions by in-cell NMR methods.

46 otein, Rd-apocyt b(562), by multidimensional NMR methods.

47 mined in solution at pH 5.0 by heteronuclear NMR methods.

48 turally characterized using multidimensional NMR methods.

49 e II TGFbeta receptor determined by solution NMR methods.

50 sample, can readily be measured by solution NMR methods.

51 was determined by standard 3-D heteronuclear NMR methods.

52 n assigned using COSY, NOESY, HSQC, and HMBC NMR methods.

53 V-1 reverse transcriptase (RT) determined by NMR methods.

54 0-tetrahydrobenzo[a]pyrene was studied by 2D NMR methods.

55 solution structure of NuiA was determined by NMR methods.

56 urified, and analyzed using multidimensional NMR methods.

57 with intact vinyl substituents was solved by NMR methods.

58 ants for the formation of pseudorotaxanes by NMR methods.

59 atch site in bold), as determined by 2D (1)H NMR methods.

60 ng heteronuclear, (1)H,(15)N-high-resolution NMR methods.

61 and rotational echo double-resonance (REDOR) NMR methods.

62 (1)H NMR signals on the basis of standard 2D NMR methods.

63 analysis of the protein by multidimensional NMR methods.

64 iology when measured and analyzed by in vivo NMR methods.

65 ar-weight proteins, using modern solid state NMR methods.

66 -observe and (15)N,(1)H-HSQC protein-observe NMR methods.

67 ctral data deduced by UHPLC-DAD-ESI-HRMS and NMR methods.

68 ex, as characterized by crystallographic and NMR methods.

69 mum), using volumetric, gravimetric, and PFG-NMR methods.

70 ion and structure determination by classical NMR methods.

71 s and congeners are determined using dynamic NMR methods.

72 ly characterised using HPLC-MS/MS, 1D and 2D NMR methods.

73 gned as a pyrano[3,2-b]pyran on the basis of NMR methods.

74 ly amenable to drug screening by traditional NMR methods.

75 as first determined through modern RDC-based NMR methods.

76 multidimensional nuclear magnetic resonance (NMR) methods.

77 D using solution nuclear magnetic resonance (NMR) methods.

78 stallography and nuclear magnetic resonance (NMR) methods.

79 with solid-state nuclear magnetic resonance (NMR) methods.

80 al heteronuclear nuclear magnetic resonance (NMR) methods.

81 al heteronuclear nuclear magnetic resonance (NMR) methods.

82 GLC, and HPLC) and spectral (UV, MS, and 1H NMR) methods.

83 one- and two-dimensional Time-domain NMR (TD-NMR) methods.

84 A combination of (13)C and (23)Na NMR methods allowed the recording of intra- and extracel

85 ation of solute hydrogen bond acidities, the NMR method allows the determination of A values for indi

86 pplication of the (1)H off-resonance R(1rho) NMR method and low temperature (185-175 K) to resolve in

87 both the traditional molar conductivity/PFG-NMR method and the rho, eta, lambda method.

88 Employing a combination of NMR methods and computer-based structural refinement, st

89 The structure was elucidated by 2D NMR methods and confirmed by X-ray crystallographic anal

90 determined by detailed two-dimensional (2D) NMR methods and confirmed by X-ray crystallographic anal

91 e dsRNA binding surface of NS1A-(1-73) using NMR methods and describe the 2.1-A x-ray crystal structu

92 ntally measure the pKa of O2' by kinetic and NMR methods and find it to be lower in the presence of d

93 Recent developments that have accelerated 2D NMR methods and improved quantitation have made these me

94 ose integration of solution- and solid-state NMR methods and is generally applicable to shed light on

95 ts were determined using a combination of 2D NMR methods and mass spectrometry.

96 These new proteins are shown by NMR methods and molecular dynamics simulations to be ver

97 its diagnostic mutant, Y123W, using solution NMR methods and molecular dynamics simulations.

98 2D NMR methods and molecular modeling using NMR-derived res

99 oligonucleotides have been examined using 2D NMR methods and molecular modeling.

100 structure of the isolated CBP TAZ1 domain by NMR methods and show that it has the same structure in t

101 has been elucidated by crystallographic and NMR methods and shows a high degree of structural conser

102 Two-dimensional NMR methods and spectral synthesis were employed to assi

103 of human DNA pol lambda via multidimensional NMR methods and the ARIA program.

104 its dynamic properties were investigated by NMR methods and with the aid of a model compound lacking

105 d bicyclic compounds were reliably proved by NMR methods and X-ray diffraction analysis.

106 ducts has been defined by X-ray analyses and NMR methods, and both chelating and monodentate binding

107 ted mutants, dynamic motion information from NMR methods, and correlated motions from MD simulations

108 y structure have recently been determined by NMR methods, and does not have precedent among known DNA

109 oil and humin, by both CP-MAS and DP-MAS 13C NMR methods, and that the problem is more serious for CP

110 ar quadruplex has been previously studied by NMR methods, and the present X-ray structure is in accor

111 The solid-state NMR method appears to be especially useful for determini

112 improvements in sensitivity and resolution, NMR methods are becoming more amenable to dissecting the

113 ucleotide exchange, high-resolution solution NMR methods are being applied in studying signaling of t

114 ge protein complexes by traditional solution NMR methods are difficult due to a priori requirement of

115 The NMR methods are often combined with statistical analysis

116 Solid state NMR methods are required to analyze biomass as a functio

117 ted sensitivity, nuclear magnetic resonance (NMR) methods are attractive because of their simplicity,

118 We have used complementary chemical and NMR methods as an approach to improving our understandin

119 metimes ambiguous given the range of current NMR methods available.

120 Characterization of proteins using NMR methods begins with assignment of resonances to spec

121 We present a new and efficient NMR method, BLUU-Tramp (Biophysics Laboratory University

122 ystem, the methodology used demonstrates how NMR methods can provide important insights into the stru

123 more easily measured, certain PET and (13)C NMR methods can quantify total regional signal activity

124 Consequently, an NMR method capable of measuring delta(13)C per thousand

125 was solved in aqueous buffer using 1D and 2D NMR methods combined with restrained molecular dynamics.

126 ng into a third dimension via fast-hybrid 3D NMR methods combining the speed of ultrafast 2D NMR with

127 ties of phospholipid bilayers, using several NMR methods, demonstrates that the two peptides insert t

128 ve been investigated by variable-temperature NMR methods, demonstrating that the intramolecular racem

129 , by using a combination of multidimensional NMR methods, density functional theory calculations and

130 One of the main goals of NMR method development is to increase the sensitivity of

131 ed by broad lines which make direct study by NMR methods difficult; this broadening arises from confo

132 entional imaging techniques, in- and on-cell NMR methods do not provide spatial information on cellul

133 or XAG region of duplexes elude discovery by NMR methods (especially because of the flexible nature o

134 ese NOE effects demonstrate a solution (19)F NMR method for analysis of tertiary contacts in high mol

135 In previous works, we developed a (13)C NMR method for analyzing triacylglycerols in olive oil u

136 saturation transfer (DEST), a novel solution NMR method for characterizing, at atomic resolution, the

137 atly extends the range of application of the NMR method for determination of residue-specific, side-c

138 Here we introduce a (1)H NMR method for determining position-specific (13)C/(12)C

139 co-workers disclosed a straightforward (19)F-NMR method for determining the log P values of fluorocar

140 An NMR method for determining the three-dimensional structu

141 this work, we develop a simple and practical NMR method for extracting both energetic and dynamic inf

142 n transfer difference (STD) is a widely used NMR method for ligand screening, the selection of specif

143 A recently developed solid-state NMR method for measurement of depths in membrane systems

144 Here we describe a solution-NMR method for structural characterization of UCP2.

145 l and obtain an unbiased and high-throughput NMR method for the analysis of nucleobase preference in

146 A novel 31P NMR method for the determination of purity for the milit

147 A new NMR method for the study of ligand-protein interactions

148 to the influence of hydrogen bonding and to NMR methods for chemical kinetics, including 2D-EXSY spe

149 NMR methods for detecting false positives will be analyz

150 This study may boost the use of non-targeted NMR methods for food control.

151 h uniquely supplements X-ray diffraction and NMR methods for investigating solution conformations of

152 l benefit of the combination of SABRE and 2D NMR methods for rapid characterization of low-concentrat

153 the use of multidimensional MAS solid-state NMR methods for resolving and assigning resonances.

154 Unlike earlier NMR methods for solving the structures of protein-ligand

155 ive to traditional X-ray crystallography and NMR methods for structure-based drug design is described

156 r may help in the development of solid-state NMR methods for studying interhelical contacts in membra

157 e analyzed by high-resolution solution-state NMR methods for the first time.

158 gomer with only G.C bp's in the XGGY site by NMR methods for the first time.

159 y, there is great interest in development of NMR methods for the study of multicomponent systems in t

160 l solution-state nuclear magnetic resonance (NMR) methods for structure determination of Dsy0195, a h

161 ructural characterization of biomolecules by NMR methods frequently requires the enrichment of magnet

162 orated diffusion ordered spectroscopy (DOSY) NMR method hand-in-hand with theoretical calculations.

163 discriminator by LC-MS, further LC, MS, and NMR methods have been applied in a coordinated effort to

164 Solid-state NMR methods have been extensively applied to characteriz

165 High-resolution solid-state NMR methods have been used to analyze the conformation o

166 NMR methods have been used to characterize the structure

167 Isothermal titration calorimetry (ITC) and NMR methods have been used to independently investigate

168 Pulsed field gradient NMR methods have determined the temperature-dependent di

169 where X-ray crystallography and traditional NMR methods have failed to produce structural data.

170 Pulsed-field gradient NMR methods have now followed gradient-dependent changes

171 dimensional (2D) nuclear magnetic resonance (NMR) methods have shown to be an excellent analytical to

172 ein structures determined by either x-ray or NMR methods, if the observed (13)C(alpha) chemical shift

173 NMR methods in combination with mutagenesis and biochemi

174 able to isolate, we could characterize it by NMR methods in DMF-d7, a solvent in which it is stable a

175 we used a hybrid of solution and solid-state NMR methods in lipid bilayers and bicelles.

176 It has also been achieved by NMR methods in proteins up to 50 kilodaltons (kDa) in si

177 advantage of combining X-ray scattering and NMR methods in structural studies of dynamic, multidomai

178 onstrates the proof of concept for 1D and 2D NMR methods in the targeted and untargeted analysis of p

179 We foresee applications of these NMR methods in understanding a wide range of redox proce

180 -optimized spectroscopy (methyl-TROSY)-based NMR methods, in concert with robust strategies for incor

181 Using nuclear magnetic resonance (NMR) methods, in this study we characterized the associa

182 The structures were elucidated by using 2D-NMR methods including an INADEQUATE experiment.

183 ormone and retinoid receptors using multiple NMR methods including methyl chemical shifts, coupling c

184 ion (XRD) and in solution using multinuclear NMR methods (including DOSY, EXSY, and COSY), electrospr

185 In the study presented here, isotope-edited NMR methods, including (15)N and (13)C relaxation measur

186 The unconventional NMR method introduced and validated in this work will li

187 The (1)H NMR method is complementary to other methods of PSIA, an

188 A simple solution NMR method is presented for pucker determination of five

189 A solution-state NMR method is proposed to investigate the dynamics of pr

190 d for structure determination by traditional NMR methods is currently long, but improved hardware, au

191 Rh of alphaB-crystallin as derived from both NMR methods is found to be fully consistent with this re

192 inetic, and in one case variable-temperature NMR methods is the process of mu-phosphide bridge format

193 In contrast to established NMR methods, it does not depend on rapid exchange betwee

194 cture has been determined by two-dimensional NMR methods, molecular modeling, and molecular dynamics

195 We used three complementary NMR methods, namely amide group chemical shift titration

196 The NMR method of isotopic perturbation has been used to dis

197 s probed by X-ray crystallography and by the NMR method of isotopic perturbation in water, in two apr

198 investigation of the H-bond symmetry by the NMR method of isotopic perturbation.

199 anion was determined in chloroform using the NMR method of isotopic perturbation.

200 Different (13)C NMR methods of determining triad distributions in two po

201 While proton-based NMR methods of fragment screening (FBS) have been well d

202 Using the solution NMR methods of residual dipolar coupling analysis, we de

203 port two in situ nuclear magnetic resonance (NMR) methods of studying redox flow batteries, which are

204 nals assigned by multidimensional Pure Shift NMR methods, P(A) can be easily and accurately determine

205 Recent NMR methods permit direct detection of hydrogen bonds th

206 at precludes characterization by traditional NMR methods permits the observation of DEST.

207 nctions in health and numerous diseases, the NMR method presented here potentially opens a new chapte

208 Our NMR method presents a precise and robust measure of RAS

209 ructures of multidomain proteins by solution NMR methods presents a number of unique challenges relat

210 fluorescence and nuclear magnetic resonance (NMR) methods, proflavine has been identified, through a

211 lication of these ultrafast multidimensional NMR methods provides the opportunity to determine the st

212 Using NMR methods providing single-residue resolution and quan

213 increases in the Stokes radius determined by NMR methods result from replacement of five isoleucine/v

214 analysis of measurement uncertainty for the NMR method resulted in combined standard uncertainties t

215 rmediate peptide concentrations, solid-state NMR methods reveal that chrysophsin-1 is aligned paralle

216 using X-ray crystallography and (19)F-based NMR methods, revealing the nature of the catalytically r

217 Here we describe a new NMR method, SALMON (solvent accessibility, ligand bindin

218 The performance of a variety of NMR methods (SGO, IGAIM, CSGT) were also examined but we

219 ng in both enzymes as determined by solution NMR methods show some striking similarities.

220 estigations of the structure and dynamics by NMR methods show that G37A retains the average WT struct

221 ith respect to the bilayer, established with NMR methods, shows that the N-terminal helix of EF-1 is

222 determination of this symmetric oligomer by NMR methods, specifically in sorting ambiguous interatom

223 n contrast to more conventional quantitative NMR methods, stem coaxial inserts are placed into the sa

224 A, we applied a combination of heteronuclear NMR methods, such as heteronuclear single quantum cohere

225 Here, we highlight recent progress in the NMR methods tailored to investigate allostery with the g

226 icability of a simple one-dimensional proton NMR method that exploits enhanced spin diffusion among p

227 We have developed an NMR method that selectively edits for organophosphorus c

228 1 order of magnitude lower than established NMR methods that employ direct protein detection for Kd

229 es in micelles was determined using solution NMR methods that rely on the measurement of backbone (1)

230 ) RNA is presented using recently introduced NMR methods that rely on the measurement of residual dip

231 se relaxation optimized spectroscopy (TROSY) NMR methods that Rev1-BRCT domain directly interacts wit

232 has a significant sensitivity advantage over NMR methods that utilize direct detection of (13)C.

233 We have determined by solution NMR methods the atomic resolution structure of an unphos

234 ted RNA structures in the PDB were solved by NMR methods, the usefulness of NMR is still limited by t

235 We developed a novel (13)C NMR method to assess effects of free fatty acids on mole

236 We present a paramagnetic NMR method to determine intermolecular structure restrai

237 We describe a simple and reliable NMR method to distinguish viscosity effects from binding

238 Here, we introduce an NMR method to identify residues involved in allosteric c

239 Here, we report a sensitive (1)H/(2)H NMR method to measure the kinetics of lactate isotopomer

240 We used a field-cycling NMR method to observe boron pure quadrupole resonance of

241 Here, we present a cost-efficient NMR method to quantify the rotational dynamics of guanin

242 Application of the stopped-flow NMR method to the study of the kinetics of 1-hexene poly

243 We used NMR methods to characterize Rheb tethered to nanodiscs,

244 In the present study we use NMR methods to define a length scale for the FF I-N tran

245 e determined by chemical and high resolution NMR methods to define the features of each serotype.

246 Here, we use a combination of NMR methods to detect four distinct sparsely populated a

247 Here, we have used NMR methods to determine the solution structures of the

248 Here we use NMR methods to determine the structure of a Lys63-linked

249 Here, we used NMR methods to determine which SipD residues are affecte

250 We use high-resolution (1)H solution NMR methods to establish the location of the Antp(43-58)

251 we use multidimensional (1)H/(15)N solution NMR methods to establish the structural and dynamics bas

252 ogues) and high resolution field cycling 31P NMR methods to estimate internal correlation times (tauc

253 We used solid-state NMR methods to examine amyloid formed in vitro from reco

254 We have used solid-state NMR methods to examine polypeptide and hydrate ordering

255 The application of rapid MAS NMR methods to investigate proton distributions in a wid

256 ructure of human cterRAP74, and we have used NMR methods to map the cterFCP-binding sites for both ct

257 Here we use time-resolved diffusion NMR methods to measure the diffusion coefficients (D) of

258 Here, we used (2)H static solid-state NMR methods to probe the dynamics of selected side chain

259 We have used heteronuclear NMR methods to probe the loop conformations in solution

260 a formamido group, was recently found using NMR methods to recognize T*G mismatched base pairs.

261 e widths enabled the use of multidimensional NMR methods to resolve overlapping (31)P signals.

262 The feasibility of applying NMR methods to stable isotope-labeled, protease-cleaved,

263 ent study, we present previously undescribed NMR methods to study the interactions of proteins with t

264 will increase the applicability of solution NMR methods to the characterization of nanomaterials.

265 We have applied GC and NMR methods to the study of intermediates found in methy

266 e observed and characterized by conventional NMR methods under conditions in which the interaction wo

267 We report that competition-based NMR methods, using 2OG as a reporter ligand, can be used

268 The unconventional NMR method validated in this work will likely prove inva

269 An NMR method was developed for determining binding sites o

270 ted by Fru-2,6-P2 in intact animals, a novel NMR method was developed using [U-13C]glucose and 2H2O a

271 A nuclear magnetic resonance (NMR) method was developed to quantify cations in mineral

272 Using heteronuclear NMR methods we have investigated the domain interactions

273 e-quantum methyl-based relaxation dispersion NMR methods we identify critical residues for DNAJB6b ol

274 ere, using the power of nonuniformly sampled NMR methods we investigate the folding pathway of amyloi

275 Furthermore, using NMR methods, we conclusively demonstrated that 6 binds t

276 imensional and three-dimensional solid-state NMR methods, we find that Delta113-120 PrP23-144 fibrils

277 Here, using HPLC-UV, LC-MS, and NMR methods, we identify a novel activity of fusion prot

278 Using NMR methods, we mapped the interaction of M50 with a hig

279 Using analytical ultracentrifugation and NMR methods, we show here that a membrane-soluble peptid

280 Using homonuclear rotational resonance NMR methods, we show that the internuclear distances bet

281 (13)C magic-angle-spinning NMR methods were applied to investigate structural and d

282 ification, and quantification of the drug by NMR methods were surveyed, as well as the use of NMR-bas

283 Double-resonance 17O/51V NMR methods were used as confirmation of the assignments

284 In a previous study, (1)H NMR methods were used to correlate the effects of crypti

285 In the present study, NMR methods were used to correlate the effects of crypti

286 Solution NMR methods were used to determine a high resolution str

287 In this work, NMR methods were used to determine the solution structur

288 Heteronuclear NMR methods were used to determine the solution structur

289 In the present work, NMR methods were used to determine the solution structur

290 Solid-state NMR methods were used to examine the size and heterogene

291 In situ X-ray diffraction (XRD) and NMR methods were used to follow the structural changes t

292 Two-dimensional relaxation NMR methods were used to investigate the correlation tim

293 In this study, NMR methods were used to investigate the sequence depend

294 In this study, heteronuclear NMR methods were used to study the structures of the DNA

295 NMR methods were used to track R*-triggered guanine nucl

296 spectrometry and nuclear magnetic resonance (NMR) methods were thus used to directly characterize the

297 In this study, nuclear magnetic resonance (NMR) methods were used to investigate the transit of sin

298 Nuclear magnetic resonance (NMR) methods were used to study whether there are differ

299 resolution two-dimensional pure-shift zCOSY NMR method with homonuclear band-selective decoupling in

300 inor groove adduct structure was observed by NMR methods with all Watson-Crick base pairs intact, and

301 ement with models obtained using traditional NMR methods with larger restraint sets.