ライフサイエンスコーパス: NOD-like receptor

1 -like receptors, C-type lectin receptors and NOD-like receptors.

2 of pathogen-associated molecular patterns by Nod-like receptors.

3 ammasome components, including caspase 1 and Nod-like receptors.

4 responses mediated by both the TLRs and the NOD-like receptors.

5 TLRs, and nucleotide oligomerization domain (NOD)-like receptors.

6 r Toll-like receptors (TLRs) 1, 2, 4, and 6; NOD-like receptor 2; and the signaling adaptor molecule

7 e nucleotide-binding oligomerization domain (NOD)-like receptor 3 (NLRP3) inflammasome has been impli

8 Furthermore, baicalein reduced NOD-like receptor 3 (NLRP3) inflammasome activation and

9 hogen-associated molecular patterns activate Nod-like receptor 3, which activates caspase-1 through t

10 AE is dependent on ASC and caspase-1 but not Nod-like receptor 3.

11 or and regulatory interactions with TLRs and Nod-like receptors, Ag presentation, naive T cell repert

12 owever, their usefulness in conjunction with NOD-like receptor agonists remains poorly studied.

13 Nucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-binding le

14 f nucleotide-binding oligomerization domain (NOD)-like receptors and DEAD-box or DEAH-box RNA helicas

15 Remarkably, a conserved fungal NOD-like receptor and prion pair can functionally recons

16 hat have common structural features with the Nod-like receptors and are essential for protection agai

17 all RNAs, including microRNAs, that regulate NOD-like receptors and defence signalling pathways in th

18 cells as microbial sensors through TLRs and Nod-like receptors and identify Nod1 and RICK as importa

19 IRF5 signaling axis functions independent of NOD-like receptors and is critically required for the re

20 NF-kappaB downstream of Toll-like receptors, Nod-like receptors, and the T cell receptor.

21 complex, plant R proteins and related animal Nod-like receptors, and with the Hsp90 molecular chapero

22 d nucleotide binding oligomerization domain (NOD)-like receptors are critical for IL-1-dependent host

23 Toll-like receptors and NOD-like receptors are families of innate immune recepto

24 *Nod-like receptors are important for maintenance of gast

25 ding oligomerization domain-like receptor or NOD-like receptors are pattern recognition receptors cap

26 in leucine-rich-repeat-containing receptors; NOD-like receptors) are a class of pattern recognition r

27 e nucleotide-binding oligomerization domain (NOD)-like receptors belong to the family of pattern reco

28 e cluster also encoding a lipase (SBP) and a Nod-like receptor, both of which display the PP motif.

29 d nucleotide-binding oligomerization domain (NOD)-like receptor C4 (NLRC4) were associated with neutr

30 in receptors Toll-like receptor 5 (TLR5) and NOD-like receptor C4 (NLRC4).

31 em (T3SS) needle complex that induces NLRC4 (NOD-like receptor C4) activation, interleukin-1beta (IL-

32 Here, we show that the cytosolic PRR Nod-like Receptor CARD 4 (NLRC4) suppresses, rather than

33 Toll-like receptors and Nod-like receptors, collectively referred to as pattern

34 endent of new production of pro-IL-1beta and NOD-like receptor components.

35 e nucleotide-binding oligomerization domain (NOD)-like receptor containing pyrin domain 3 (NLRP3) inf

36 beta by sterile particles is mediated by the NOD-like receptor containing a pyrin domain 3 (NLRP3) in

37 B. abortus was diminished in the absence of Nod-like receptor containing a pyrin domain 3 and absent

38 Both absent in melanoma 2 and Nod-like receptor containing a pyrin domain 3 are partia

39 ors encoding a PYD belong to the families of NOD-like receptors containing a PYD (NLRPs) or AIM2-like

40 specific angiogenic responses in a TLR- and NOD-like receptor-dependent fashion.

41 r nucleotide-binding oligomerization domain (NOD)-like receptors, detect tissue damage or microbial i

42 e transcriptional upregulation of the NLRP3 (Nod Like Receptor Family Pyrin Domain-Containing 3) infl

43 e transcriptional upregulation of the NLRP3 (Nod Like Receptor Family Pyrin Domain-Containing 3) infl

44 re, we demonstrate that double deficiency of Nod like receptor family, pyrin domain containing 3 (NLR

45 e nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 12 (NL

46 d nucleotide-binding oligomerization domain (NOD)-like receptor family, pyrin domain containing 3 act

47 Nucleotide-binding oligomerization domain (NOD)-like receptor family, pyrin domain-containing prote

48 e nucleotide-binding oligomerization domain (NOD)-like receptors family members are key for innate im

49 Members of the Nod-like receptor family (including Nlrp1, Nlrp3, and Nl

50 Several members of the nod-like receptor family assemble inflammasome in respon

51 Nod-like receptor family card containing 4 (NLRC4)/Ipaf

52 n facilitated by breastmilk feeding promotes NOD-like receptor family CARD domain containing 5 (Nlrc5

53 les, and their key transcriptional activator NOD-like receptor family CARD domain containing 5.

54 in-interaction network, missense variants in NOD-like receptor family genes (NOD2, NLRC4, NLRP3, and

55 The Nod-like receptor family in man contains proteins that r

56 e recently found that asbestos activates the nod-like receptor family member containing a pyrin domai

57 learance during IAV infection.IMPORTANCE The NOD-like receptor family member NLRC5 is known to regula

58 NOD-like receptor family member NLRP12 was shown to supp

59 f caspase-1, through a process requiring the NOD-like receptor family member NLRP3 and the inflammaso

60 Here, we report that NLRX1, a NOD-like receptor family member, negatively regulates To

61 The NOD-like receptor family members and the NALP3 inflammas

62 f bacterial peptidoglycan that belong to the Nod-like receptor family of innate immune proteins.

63 show that NOD1 and NOD2, two members of the NOD-like receptor family of PRRs, are important mediator

64 ion-induced caspase-1 activation occurs by a Nod-like receptor family protein 3-independent mechanism

65 reated group via engagement of the canonical NOD-like receptor family pyrin domain containing 3 (NLRP

66 mplications, in particular activation of the Nod-like receptor family pyrin domain containing 3 (NLRP

67 tau pathology, with evidence suggesting the nod-like receptor family pyrin domain containing 3 (NLRP

68 mplications, in particular activation of the Nod-like receptor family pyrin domain containing 3 (NLRP

69 flow, and local tissue hypoxia activate the NOD-like receptor family pyrin domain containing 3 infla

70 tely on inhibition of the IL-1beta-producing NOD-like receptor family pyrin domain containing 3 infla

71 ultures, internalized MAC also causes NLRP3 (NOD-like receptor family pyrin domain containing 3) tran

72 nt Domain (CARD)), pro-caspase-1, and NLRP3 (NOD-Like Receptor family Pyrin domain containing 3).

73 CRC development, where mice deficient in the NOD-like receptor family pyrin domain containing 6 (NLRP

74 NOD-like receptor family pyrin domain containing 6 (NLRP

75 Notably, NOD-like receptor family pyrin domain containing 6 (NLRP

76 his study aims to compare salivary levels of nod-like receptor family pyrin domain containing protein

77 to IL-1 and IL-18, suggesting a role for the NOD-like receptor family pyrin domain containing-3 infla

78 ins induced release of IL-1beta dependent on NOD-like receptor family pyrin domain-containing 3 (NLRP

79 The NOD-like receptor family pyrin domain-containing 3 (NLRP

80 nd to the Toll-like receptor 4 and prime the nod-like receptor family pyrin domain-containing 3 infla

81 signaling or their downstream mediators (eg, nod-like receptor family pyrin domain-containing 3 infla

82 ssion of key inflammatory mediators, such as NOD-like receptor family pyrin domain-containing 3, inte

83 Host NOD-like receptor family pyrin domain-containing 6 (NLRP

84 The SREBP-induced NOD-like receptor family pyrin domain-containing protein

85 manner, which leads to the activation of the NOD-like receptor family pyrin domain-containing protein

86 Annexin A1 (ANXA1) and the NOD-like receptor family pyrin domain-containing protein

87 Nod-like receptor family pyrin domain-containing protein

88 s as well as expression of components of the NOD-like receptor family pyrin domain-containing protein

89 NOD2 is a member of the NOD-like receptor family that initiates inflammatory sig

90 NLRC4 is a cytosolic member of the NOD-like receptor family that is expressed in innate imm

91 NLRX1, a member of the Nod-like receptor family that translocates to the mitoch

92 Members of the Nod-like receptor family, including NLRP1, NLRP3 and NLR

93 ain (Nod)1, a member of the intracytoplasmic Nod-like receptor family, induced potent secretion of th

94 NLRP12, a member of the NOD-like receptor family, is expressed in myeloid and bo

95 Activation of the NOD-like receptor family, pyrin domain containing 3 (NLR

96 an neutrophils express key components of the NOD-like receptor family, pyrin domain containing 3 (NLR

97 NOD-like receptor family, pyrin domain containing 3 (NLR

98 ata are pointing to an important role of the NOD-like receptor family, pyrin domain containing 3 (NLR

99 ns of chitosan, but not chitin, activate the NOD-like receptor family, pyrin domain containing 3 (NLR

100 er report that these effects are mediated by NOD-like receptor family, pyrin domain containing 3 (NLR

101 The NOD-like receptor family, pyrin domain containing 3 (NLR

102 linked to gain-of-function mutations in the NOD-like receptor family, pyrin domain containing 3 (NLR

103 of the mature IL-1beta form depended on the NOD-like receptor family, pyrin domain containing 3 (NLR

104 We hypothesized that Gal3 is a key to induce NOD-like receptor family, pyrin domain containing 3 (NLR

105 eroxide in the mechanisms tightly regulating NOD-like receptor family, pyrin domain containing 3 acti

106 t transient, increase in the activity of the NOD-like receptor family, pyrin domain containing 3 infl

107 The key role of the NOD-like receptor family, pyrin domain containing 3 infl

108 nt thinking, an early intervention targeting NOD-like receptor family, pyrin domain containing 3 infl

109 The NLRP3 (NOD-like receptor family, pyrin domain containing 3) inf

110 recent evidence that the NOD2 target, NLRP3 (NOD-like receptor family, pyrin domain containing 3) is

111 leading to enhanced Caspase-1/Caspase-4- and NOD-like receptor family, pyrin domain containing 3-depe

112 r interacting protein kinase 1), and NLRP12 (NOD-like receptor family, pyrin domain-containing 12)-PA

113 The NOD-like receptor family, pyrin domain-containing 3 (NLR

114 re we show that bee venom is detected by the NOD-like receptor family, pyrin domain-containing 3 infl

115 tidylarginine deiminase 4, and activates the NOD-like receptor family, pyrin domain-containing 3 infl

116 several studies have focused on the role of nod-like receptor family, pyrin domain-containing protei

117 1 and NOD2, two members of the intracellular NOD-like receptor family, sense bacterial peptidoglycan-

118 2, the founding members of the intracellular NOD-like receptor family, sense conserved motifs in bact

119 lular stress is activation of members of the NOD-like receptor family, such as NLRP3, to assemble cas

120 best characterized members of the cytosolic NOD-like receptor family.

121 1 has long remained an elusive member of the NOD-like-receptor family of innate immune sensors.

122 ide-binding domain leucine-rich repeat (NLR; NOD-like receptor) family of pattern recognition recepto

123 The specific ligands for some NOD-like receptors have been identified.

124 llular pattern recognition receptors such as NOD-like receptors have been minimally studied.

125 tosis, and signaling pathways including p53, NOD-like receptor, IL-17, NF-kappa B, and PI3K-Akt.

126 omoting colon tumorigenesis, but the role of Nod-like receptors in regulating tumorigenesis remains u

127 as HMGB1 and IL-1beta, Toll-like receptors, Nod-like receptors including NLRC4, NLRP3 and NLRP4, and

128 nduces caspase 1 activation through multiple Nod-like receptors, including Ipaf and Nalp3.

129 lar endothelial growth factor inhibited TLR-/NOD-like receptor-induced HIMEC angiogenesis.

130 ror rate, FWER p-value <0.05), including the NOD-like receptor inflammasome (NLR; p < 0.001), toll-li

131 roducts in the cytosol of mammalian cells by NOD-like receptors leads to the activation of caspase-1

132 the detection of bacterial products through Nod-like receptors leads to the secretion of mature inte

133 and plays an important role in both TLR and NOD-like receptor ligand induced inflammation.

134 MAPK, mitogen-activated protein kinase; NLR, NOD-like receptors; LRR, leucine-rich repeats; DC, dendr

135 mmune receptors, the Toll-like receptors and Nod-like receptors, many of which are upstream of nuclea

136 ment in vivo results in up-regulation of the Nod-like receptor member Nod1, which recognizes the prod

137 evidence for AS of LRR domain within several Nod-like receptors, most prominently the inflammasome se

138 The Nod-like receptor NACHT, LRR, and PYD domain-containing

139 Once detected by the NOD-like receptors Naip5 and Ipaf (Nlrc4), flagellin tri

140 The NOD-like receptors NAIP5 and NLRC4 play an essential rol

141 e nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) (nucleotide-binding domain leuc

142 cleotide-binding and oligomerization domain (NOD)-like receptor (NLR) family contribute to immune res

143 e nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain-containing

144 e nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain-containing

145 pathways and Nuclear Oligomerization Domain (NOD)-Like Receptor (NLR) pathways and Caspase networks.

146 Nucleotide-binding, oligomerization domain (NOD)-like receptor (NLR) proteins are a family of innate

147 n nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) proteins.

148 d nucleotide binding oligomerization domain (Nod)-like receptors (NLR), Nod1 and Nod2, as novel regul

149 , including the Toll-like receptor (TLR) and Nod-like receptor (NLR) families.

150 NOD-like receptor (NLR) family CARD domain containing 3

151 agellin secreted by Salmonella activates the Nod-like receptor (NLR) family CARD domain containing pr

152 timulation of innate immune receptors of the NOD-like receptor (NLR) family causes significant damage

153 cular mechanisms promoting activation of the Nod-like Receptor (NLR) family member NLRP3 inflammasome

154 NOD2 is a NOD-like receptor (NLR) family member that senses and re

155 flammasome, a multiprotein complex formed by NOD-like receptor (NLR) family members, has recently bee

156 The Nod-like receptor (NLR) family of innate immune cell sen

157 The Nod-like receptor (NLR) family of innate immune cell sen

158 NLRC4 and NLRP3, of the NOD-like receptor (NLR) family of intracellular proteins

159 Members of the NOD-like receptor (NLR) family of pathogen recognition r

160 Nod1, a member of the Nod-like receptor (NLR) family of pattern recognition re

161 NALP1 is a member of the NOD-like receptor (NLR) family of proteins that form inf

162 scriptomic changes, including alterations in NOD-like receptor (NLR) family pyrin domain-containing 1

163 h several inflammasome components, including NOD-like receptor (NLR) family pyrin domain-containing 3

164 The NOD-like receptor (NLR) family pyrin-domain-containing 3

165 Members of the Nod-like receptor (NLR) family, including NLRP1, NLRP3 a

166 Activating-mutations in NOD-like receptor (NLR) family, pyrin domain-containing

167 The NOD-like receptor (NLR) family, pyrin domain-containing

168 Nlrp1b belongs to the Nod-like receptor (NLR) gene family and contributes to i

169 of nucleotide-binding leucine rich repeat or Nod-Like Receptor (NLR) genes as an important mechanism

170 r histocompatibility complex (MHC) genes and NOD-like receptor (NLR) genes, mediators of direct and i

171 bind to the enhancer region of two adjacent NOD-like receptor (NLR) genes, NLR family pyrin domain-c

172 sensed and restricted in vivo, especially by NOD-like receptor (NLR) inflammasomes, is largely unknow

173 ld be rescued by administration of bacterial Nod-like receptor (NLR) ligands (the NOD1 ligand MurNAcT

174 C)/PYCARD, a central adaptor molecule in the Nod-like receptor (NLR) pathway, regulates the IL-18/IFN

175 NOD1 and NOD2 are members of the NOD-like receptor (NLR) protein family that are involved

176 NLRC5, a member of the NOD-like receptor (NLR) protein family, has recently bee

177 previously reported inhibitory effect of the Nod-like receptor (NLR) protein NLRX1 on NF-kappaB- and

178 NLRX1 is a mitochondrial Nod-like receptor (NLR) protein whose function remains e

179 have been identified in the NACHT domains of Nod-like receptor (NLR) proteins.

180 n response to canonical stimuli initiated by NOD-like receptor (NLR), and apoptosis-associated speck-

181 NOD2, a NOD-like receptor (NLR), is an intracellular sensor of b

182 At steady state, the NOD-like receptor (NLR)-containing pyrin domain (PYD) (N

183 riggered immunity but triggers intracellular NOD-like receptor (NLR)-mediated autoimmunity with an el

184 is activated through amyloid templating by a Nod-like receptor (NLR).

185 orphisms (SNP) of toll-like receptors (TLR), NOD-like receptors (NLR) and RIG-I-like receptors (RLR)

186 NOD-like receptors (NLR) are critical regulators of inna

187 ing evidence highlights additional roles for Nod-like receptors (NLR) in nonhematopoietic cells.

188 Toll-like receptors and Nod-like receptors (NLR) play an important role in sensi

189 A diverse class of PRRs, the NOD-like Receptors (NLR), has recently been implicated i

190 pathogen recognition receptors, known as PYD-Nod-like receptors (NLR), PAN, PYPAF, NALP, Nod, and Cat

191 rs, such as Toll-like receptors (TLR) and/or Nod-like receptors (NLR).

192 -associated speck-like protein (ASC) and the NOD-like receptor NLRC4 are significantly down-regulated

193 in a mouse we recently described lacking the NOD-like receptor NLRP10 (NLR family, pyrin domain conta

194 The intracellular NOD-like receptor Nlrp3 is rapidly emerging as a crucial

195 als, stimulates the inflammasome through the Nod-like receptor NLRP3.

196 aureus exoproteins through activation of the NOD-like receptors NLRP3 and NLRP4 and enhanced phagocyt

197 osolic pattern recognition receptors such as NOD-like receptors, NLRP3 inflammasomes.

198 r nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) and the adaptor ASC is believ

199 r nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) and they initiate innate immu

200 e nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are a family of intracellular

201 cleotide oligomerization and binding domain (NOD)-like receptors (NLRs) are a major constituent of th

202 cleotide oligomerization and binding domain (NOD)-like receptors (NLRs) are important in the innate i

203 cleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) have shaped our current under

204 f nucleotide binding oligomerization domain (NOD)-like receptors (NLRs) in innate detection of influe

205 cleotide oligomerization and binding domain (NOD)-like receptors (NLRs), caspase-1, and in some cases

206 n nucleotide binding oligomerization domain (NOD)-like receptors (NLRs), retinoic acid-inducible prot

207 NOD-like receptors (NLRs) and caspase-1 are critical com

208 NOD-like receptors (NLRs) are a highly conserved family

209 The NOD-like receptors (NLRs) are a specialized group of int

210 NOD-like receptors (NLRs) are central components of the

211 NOD-like receptors (NLRs) are increasingly implicated in

212 underway and have already revealed specific NOD-like receptors (NLRs) as inflammatory triggers.

213 In contrast, the role of NOD-like receptors (NLRs) in viral recognition and induc

214 NOD-like receptors (NLRs) localize in the cytosol to rec

215 influence of human polymorphisms in TLRs and Nod-like receptors (NLRs) on C. burnetii-induced cytokin

216 The NOD-like receptors (NLRs) were among the first innate im

217 These receptors include cytoplasmic NOD-like receptors (NLRs) whose stimulation recruits and

218 yroptosis induction, we knocked down several NOD-like receptors (NLRs) with respective shRNAs in PBMC

219 xamine the effects of glucocorticoids on the NOD-like receptors (NLRs), a central component of the in

220 ptors, including Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors (RLR

221 leucine-rich repeat receptors, also known as NOD-like receptors (NLRs), are highly diversified, both

222 w the varied roles of one class of PRRs, the NOD-like receptors (NLRs), in immune responses and propo

223 The innate immune system encodes cytosolic Nod-like receptors (NLRs), several of which activate cas

224 Although they are among the best studied NOD-like receptors (NLRs), the therapeutic potential of

225 In order to determine the role of NOD-like receptors (NLRs), we used an experimental Esche

226 ogenous danger signals in the cytosol engage NOD-like receptors (NLRs), which assemble inflammasome c

227 nsors such as Toll-like receptors (TLRs) and NOD-like receptors (NLRs).

228 ptors (PRRs), Toll-like receptors (TLRs) and NOD-like receptors (NLRs).

229 bial sensors have been identified, including NOD-like receptors (NLRs).

230 cognition receptors (PRRs) and intracellular NOD-like receptors (NLRs).

231 and orientation on the binding affinities of NOD-like receptors (NLRs).

232 like receptors and the more recently defined NOD-like receptors (NLRs): NODs, NALPs, NAIP and IPAF.

233 Both plants and animals carry NOD-like-receptors (NLRs).

234 cleotide-binding and oligomerization domain (NOD)-like receptors NOD1 and NOD2 are cytosolic innate i

235 veral innate immune receptors, including the NOD-like receptors (NOD1 and NOD2).

236 g IL-22 secretion by iNKT cells, whereas the NOD-like receptors NOD2 and NLRP3 are dispensable.

237 Among various NOD like receptors, NOD2 was significantly upregulated i

238 Nucleotide-binding oligomerization domain (NOD)-like receptors of which there are more than 20 rela

239 ins of plants (R-proteins) and the so-called NOD-like receptors of animals (NLRs) share a domain arch

240 mous substitutions in NOD-2, a member of the NOD-like receptor or NACHT-leucine-rich repeat (NLR) fam

241 ction of ASC with IFI16 but not with AIM2 or NOD-like receptor P3 (NLRP3) was detected.

242 ase of IL-1alpha, which was still high after Nod-like receptor P3 inhibition via glibenclamide.

243 reptococcus (GBS)-mediated activation of the Nod-like receptor-P3 (NLRP3) inflammasome in macrophages

244 NOD-like receptors play a role in regulation of innate i

245 cine-rich repeat-containing protein (NLR or (NOD-like)) receptors play a critical role in the innate

246 e nucleotide-binding oligomerization domain (NOD)-like receptor protein 3 (NLRP3) inflammasome to rec

247 his study was that sustained activity of the Nod-like receptor protein (NLRP)-3 inflammasome in wound

248 as well as the inflammation mediated by the NOD-like receptor protein (NLRP)-3/caspase-1 signaling p

249 In particular, S100A9-mediated NOD-like receptor protein 3 (NLRP3) inflammasome activat

250 emodeling, cell osmolarity and regulation of NOD-like receptor protein 3 (NLRP3) inflammasome activit

251 ian leptin signalling, the activation of the NOD-like receptor protein 3 (NLRP3) inflammasome and mac

252 thies and highlight a potential role for the NOD-like receptor protein 3 (NLRP3) inflammasome as a ne

253 tosis, in T lymphocytes through induction of Nod-like receptor protein 3 (NLRP3) inflammasome complex

254 Microglial hyperactivation of the NOD-like receptor protein 3 (NLRP3) inflammasome has bee

255 The NOD-like receptor protein 3 (NLRP3) inflammasome is a ce

256 Activation of the NOD-like receptor protein 3 (NLRP3) inflammasome pathway

257 whether inhibition of a major product of the Nod-like receptor protein 3 (NLRP3) inflammasome with ca

258 eukin-1beta (IL-1beta), which is mediated by Nod-like receptor protein 3 (NLRP3) inflammasome, cathep

259 strong activation of innate immunity induced Nod-like receptor protein 3 (NLRP3) inflammasome-indepen

260 NINJ2 promoted pyroptosis by activating the NOD-like receptor protein 3 (NLRP3) inflammasome.

261 rating TXNIP to associate with mitochondrial nod-like receptor protein 3 (NLRP3) to activate inflamma

262 a in bacterial clearance, and we showed that Nod-like receptor protein 3 (NLRP3), apoptosis-associate

263 -2), inducible nitric oxide synthase (iNOS), nod-like receptor protein 3 (NLRP3), associated speck-li

264 this process leads to the activation of the Nod-like receptor protein 3 inflammasome and the subsequ

265 The TLR2 ligand increased Nod-like receptor protein 3, an inflammasome component,

266 Similar to Ipaf and caspase-1, the Nod-like receptor protein Naip5 restricts intracellular

267 cent studies revealed a crucial role for the NOD-like receptor protein Nlrp3 in regulating inflammati

268 The NOD-like receptor protein-3 (NLRP3) inflammasome contrib

269 review, we will summarize the centrality of Nod-like receptor proteins that assemble inflammasomes a

270 g domain, leucine-rich repeat containing, or NOD-like receptor) proteins is in inflammasome activatio

271 e also increased measures of senescence, the nod like receptor pyrin domain containing 3 (NLRP3) infl

272 e nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing family of gen

273 by some immune receptors, they activate the NOD-like receptor pyrin 3-inflammasome and trigger IL-1b

274 n the regulatory region of the gene encoding NOD-like receptor pyrin domain containing 3 (NLRP3) have

275 The NOD-like receptor pyrin domain-containing 3 (NLRP3) infl

276 The NOD-like receptor pyrin domain-containing protein 3 (NLR

277 n endothelial cells that assembles an NLRP3 (NOD-like receptor pyrin domain-containing protein 3) inf

278 We recently demonstrated that the NOD-like receptor, pyrin domain containing-3 (NLRP3) con

279 TLRs (toll-like receptors) and NLRs (NOD-like receptors) recognize damage-associated molecula

280 ARD4 and NOD2/CARD15 proteins are members of NOD-like receptors recognizing specific motifs within pe

281 *Nucleotide binding oligomerization domain (Nod)-like receptors regulate cognition, anxiety and hypo

282 *Nod-like receptors regulate central and peripheral serot

283 ind specific receptors [Toll-like receptors, NOD-like receptors, RIG-I-like receptors, AIM2-like rece

284 oteins with an architecture like that of the NOD-like receptors, SAMD9/9L molecular functions and dom

285 ike receptor (TLR), RIG-I-like receptor, and NOD-like receptor signaling pathways of the innate immun

286 arity of epithelial cells acts on intestinal NOD-like receptor signaling to mediate spatial specifici

287 in induced enrichment of pathways related to NOD-like receptor signaling, high metabolic demand, and

288 e of Streptococcus correlated with increased NOD-like receptor signaling.

289 d Proteobacteria phyla, we found that potent Nod-like receptor-stimulating bacteria in the upper airw

290 indings expand the potential ligands for the NOD-like receptors, suggesting that other xanthone compo

291 ng from IL-1 receptors, Toll-like receptors, NOD-like receptors, T- and B-cell receptors.

292 cleotide binding and oligomerization domain (NOD)-like receptors that were found to control nonself r

293 mprises an intracellular sensor (typically a Nod-like receptor), the precursor procaspase-1 and the a

294 n-recognition proteins) and mammals (through Nod-like receptors) to bacterial invasion.

295 cell surface (TLRs) and within the cytosol (Nod-like receptors) to promote inflammatory processes ai

296 dependent on caspase-1; however, the role of Nod-like receptors upstream of caspase-1 is unknown.

297 s of the large family of intracellular NLRs (NOD-like receptors), which also includes animal immune r

298 udy, we explored how NAD(+) affects TLR4 and NOD-like receptor with a PYD-domain 3 (NLRP3) inflammaso

299 ncing of the newly discovered dsRNA receptor Nod-like receptor X-1 (NLRX-1), but not other previously

300 016) demonstrate in independent studies that Nod-like receptor X1 (NLRX1) may facilitate early system