ライフサイエンスコーパス: NTPase

1 NTPase activities in mammalian reovirus cores were exami

2 NTPase first appears 12 h postinfection.

3 NTPases that have a G-X-X-X-X-G-K-[S/T] consensus sequen

4 enetic approach to obtain a genealogy of 148 NTPase genes and reconstruct a scenario of gene superfam

5 Prior results show that the 1a NTPase/helicase-like domain contributes to RNA recruitme

6 to some double-stranded RNA viruses, the 1a NTPase/helicase-like domain may be involved in importing

7 ins with the gene order p38.3 (Nterm)-p39.6 (NTPase)-p18.6-p14.3 (VPg)-p19.2 (Pro)-p57.5 (Pol).

8 conserved mitotic-like apparatus in which a NTPase (ParA) displaces the partition complex.

9 functionally altered member of the McrB AAA+ NTPase family, which are often found as restriction enzy

10 Even after NTPase induction, these proteins were retained within cy

11 HXGPRT RNA-ribozyme construct did not alter NTPase expression nor compromise parasite replication.

12 In addition, an NTPase-defective DHX33 mutant (K94R) acted as a dominant

13 n RNA-dependent RNA polymerase (RdRP) and an NTPase VP4.

14 s, a centromere-binding protein (CBP) and an NTPase.

15 under conditions where NSP2 functions as an NTPase, its helix-destabilizing activity was less sensit

16 into nonstructural proteins that include an NTPase, VPg, protease, and RNA-dependent RNA polymerase.

17 The key component is an NTPase protein that cycles between nucleotide-dependent

18 One of these proteins, D5, is an NTPase that contains an N-terminal archaeoeukaryotic pri

19 ively, our findings suggest that DFCP1 is an NTPase that modulates the metabolism of LDs in cells.

20 en shown to form multimers and to possess an NTPase activity, but its precise function remains unclea

21 es three elements: a DNA centromere site, an NTPase, and a centromere-binding protein.

22 This study reveals for the first time an NTPase activity associated with a calicivirus-encoded pr

23 teinase domain and an RNA triphosphatase, an NTPase domain, and an RNA helicase in the C-terminal dom

24 Consistent with an NTPase activity, conserved residues predicted to be requ

25 with the protein, helix destabilization and NTPase, may function together.

26 hat the RNA-binding, helix-destabilizing and NTPase activities of tsE NSP2 were significantly less at

27 Previous studies demonstrated helicase and NTPase activities for DDX3X, but important biochemical f

28 s predicted with respect to RNA helicase and NTPase activities in vitro.

29 imization of the parameters for helicase and NTPase assays are expected to provide the starting point

30 ture, suggesting that the viral helicase and NTPase reactions are not coupled.

31 in 3 (NS3), with its protease, helicase, and NTPase enzymatic activities, plays a crucial role in vir

32 ents in Upf1p including zinc finger-like and NTPase domains, as well as all motifs common to members

33 agenesis studies showed that the primase and NTPase activities of the recombinant D5 protein could be

34 efine the functional domains of protease and NTPase/RNA helicase activities of NS3, full-length and a

35 acillus subtilis, the RNAP delta subunit and NTPase HelD have been implicated in RNAP recycling.

36 The RNA triphosphatase and NTPase activities of baculovirus LEF-4 resemble those of

37 ces between arginine fingers of dUTPases and NTPases are explained on the basis of the unique chemist

38 chanistic divergences between BY-kinases and NTPases despite their deployment of similar catalytic mo

39 ltimerization, localization and function are NTPase activity-dependent.

40 erties of full-length NS3 (NS3FL)-associated NTPase, RTPase, and RNA helicase are presented.

41 yzoite-specific nucleoside triphosphatase (B-NTPase) promoters.

42 f the OB domain also increased DHX29's basal NTPase activity, but more importantly, abrogated the res

43 Besides NTPase and other RNA helicase consensus motifs, UPF1 and

44 Both NTPase and pyrophosphatase activities were enhanced at h

45 sis showed that this mutation abolished both NTPase and helicase activities of MLE but affected the a

46 ivity alone (motif II, DEYH to DEYA) or both NTPase and helicase activity (motif I, GKT to GAT and de

47 The DEAH-box NTPase Prp43 and its cofactors Ntr1 and Ntr2 form the NT

48 The DExH-box NTPase/helicase Prp22p plays two important roles in pre-

49 DEAD/H-box NTPases remodel the spliceosome at multiple steps during

50 and Mu) and combine a CDC6/ORC1-STAND clade NTPase domain with a C-terminal REase domain.

51 To date, many house-cleaning NTPases have been identified only on the basis of their

52 of LGP2 to internal dsRNA sites complements NTPase-independent binding to dsRNA ends, via distinct b

53 Both proteins contain a conserved NTPase domain that genetic studies have demonstrated is

54 ule of ASCC that encompasses two cooperating NTPase/helicase units functionally expanded by TRIP4.

55 rally and functionally links the cytoplasmic NTPases of the system with its outer membrane and pilus

56 ional change couples rearrangement of the (d)NTPase active site to additional hydrogen-bonding betwee

57 ngs represent the first report demonstrating NTPase/RNA helicase activity of the helicase domain of H

58 nding, helix unwinding, and Mg(2+)-dependent NTPase activities and play a crucial role in assembly of

59 e a manganese-dependent and cobalt-dependent NTPase activity intrinsic to CaCet1p.

60 ificity for NTP analogues, the DNA-dependent NTPase activity associated with the herpes primase-helic

61 n catalyzes its characteristic DNA-dependent NTPase activity, and can unwind duplex DNA substrates in

62 ion, and is a DNA helicase and DNA-dependent NTPase.

63 ation system, we show that the HIT-dependent NTPase activity of NSP2 is necessary for dsRNA synthesis

64 to E. coli Rho in terms of its RNA-dependent NTPase activity and its sensitivity to the Rho-specific

65 n of the putative RNA helicase/RNA-dependent NTPase family, is a splicing factor that functions late

66 The RNA-dependent NTPase Prp43 catalyzes dissociation of excised lariat-in

67 ion factor rho is a hexameric, RNA-dependent NTPase that can adopt active closed-ring and inactive op

68 nce had on primase activity, ssDNA-dependent NTPase activity was essentially unaffected by changes in

69 ial DNA helicases are nucleic acid-dependent NTPases that play important roles in DNA replication, re

70 he DEXH-box family of nucleic acid-dependent NTPases.

71 ing an apparent CTPase domain and detectable NTPase activity.

72 When activated by dithiols, NTPase is one of the most potent apyrases known to date,

73 an arginine finger, a motif found in diverse NTPase families, due to its interdomain interaction with

74 entially converts an ecto-apyrase to an ecto-NTPase.

75 nRNP protein (hnRNP C and hnRNP U) or either NTPase protein (NAT10 and GNL3L) induced telomere shorte

76 We found that the norovirus-encoded NTPase NS3 contains an N-terminal four-helix bundle doma

77 gregate DNA, the most common plasmid-encoded NTPases contain Walker-box and actin-like folds.

78 The genes encoding NTPase have been cloned.

79 ne resulted in an ecto-apyrase with enhanced NTPase activity, but diminished NDPase activity.

80 HEV Hel exhibited NTPase and RNA unwinding activities.

81 tivity, whereas the N-terminal part exhibits NTPase and RNA triphosphatase activity and is proposed t

82 studied to date is Sal(A), a putative ABC-F NTPase that-by analogy to other proteins of this type-ma

83 uction ATPases with numerous domains) family NTPase followed by a series of LRRs, suggesting inherita

84 d that Tm-MazG has dual enzymatic functions, NTPase and pyrophosphatase, and that these two enzymatic

85 al CV amino acid motifs, including GXXGXGKT (NTPase), EYXEX (Vpg), GDCG (protease), and GLPSG and YGD

86 phatase (NTPase) assay to show that UL84 has NTPase activity, preferring UTP.

87 roteins that have not been suspected to have NTPase activity, including soluble adenylyl cyclases, ne

88 ural basis for the enzymatic activity of HCR-NTPase was further characterized by site-directed mutage

89 which further contributes to making the HCR-NTPase an attractive new target for further biochemical

90 aviviridae family contain conserved helicase/NTPase motifs in their homologous NS3 proteins.

91 To determine the role of the NS3 helicase/NTPase in the viral life cycle, deletion and point mutat

92 life cycle, the precise role of the helicase/NTPase in virus replication or whether it is essential f

93 deletion and point mutations in the helicase/NTPase motifs of the bovine viral diarrhea virus (BVDV)

94 an RNA-dependent RNA polymerase, a hexameric NTPase, and an auxiliary protein.

95 The cystoviral hexameric NTPase, P4, uses chemical energy to translocate single-s

96 ts of actin-activated heavy meromyosin (HMM) NTPase, the rates of NTP binding to myosin and actomyosi

97 rfamily of genes for putative NTP hydrolase (NTPase) proteins that are strikingly similar in structur

98 olysis common among secretion NTP hydrolase (NTPase) proteins.

99 Nucleoside triphosphate hydrolase (NTPase) is a very abundant protein secreted by the oblig

100 pe-tagged nucleoside triphosphate hydrolase (NTPase) were partially activated during immunoprecipitat

101 g the 5' nucleoside triphosphate hydrolases (NTPase).

102 Nucleoside-triphosphate hydrolases (NTPases) are a diverse, but essential group of enzymes f

103 ntaining nucleoside triphosphate hydrolases (NTPases), Bowman-Birk type proteinase inhibitors (BBI),

104 asmid pSK1 in the absence of an identifiable NTPase component.

105 s indicate that most of the immunodetectable NTPase is within the nucleus, a compartment proteins typ

106 These data implicate NTPase in an essential parasite function and suggest tha

107 In NTPases, the "arginine finger" drives the reactive confo

108 /B-C, glycosyltransferase-4 family, inactive NTPase (serving as nucleic acid receptors), and invader-

109 roteins that are widely conserved, including NTPases and secretins, and on proteins that are system s

110 rms dynamic filaments that require an intact NTPase motif for their turnover in vivo.

111 bitory role in suppressing DHX29's intrinsic NTPase activity but was not essential for its 40S-stimul

112 mediates through the energy derived from its NTPase activity.

113 ion processes, and contains tandem Ski2-like NTPase/helicase cassettes crucial for these functions.

114 Btoxis encoding a putative FtsZ/tubulin-like NTPase called TubZ and DNA-binding protein called TubR h

115 ems, NAD+/nucleotide degradation, and P-loop NTPase domains of the STAND and GTPase clades playing pi

116 study reveals that RUVBL2, which is a P-loop NTPase enzyme previously shown to affect circadian phase

117 blance to that of adenylate kinase (a P-loop NTPase enzyme).

118 ses form one of the largest clades of P-loop NTPase fold enzymes that catalyze ATP-hydrolysis and uti

119 struction of the early history of the P-loop NTPase fold includes the initial split into the common a

120 a monophyletic assemblage within the P-loop NTPase fold.

121 ts [2Fe-2S](2+) clusters to the human P-loop NTPase NUBP1, an essential early component of the cytoso

122 R-proteins are P-loop NTPase superfamily members, and current models describe

123 hly represented being ankyrin repeat, P-loop NTPase, F-box, protein kinase, and membrane occupation a

124 in contrast to other superclasses of P-loop NTPases (RecA-F1/F0, AAA+, helicases, ABC), GTPases do n

125 tif defines the Mrp/Nbp35 subclass of P-loop NTPases and is suspected to be involved in transient Fe-

126 o the last universal common ancestor, P-loop NTPases and Rossmanns comprise the most ubiquitous and d

127 In all analyzed genomes, the P-loop NTPases are the most abundant fold.

128 proteins are distinguished from other P-loop NTPases by the presence of unique sequence motifs associ

129 The essential P-loop NTPases Cfd1 and Nbp35 of the cytosolic iron-sulfur (Fe-

130 totypes", thus relate to contemporary P-loop NTPases in terms of their sequence and function, and yet

131 P-loop NTPases of the ApbC/Nbp35 family are involved in FeS pro

132 ve-site elements in myosins and other P-loop NTPases play critical roles in nucleotide binding and hy

133 biguously distinguish them from other P-loop NTPases such as an alternative to arginine-finger-based

134 nimals, Cfd1 and Nbp35 are homologous P-loop NTPases that form a heterotetrameric complex essential f

135 ional strand, catalytic E division of P-loop NTPases together with the AAA+ ATPases, RecA/helicase-re

136 dditional strand catalytic 'E' (ASCE) P-loop NTPases, GHL proteins, actin-fold enzymes and chaperonin

137 latter ligates the catalytic metal in P-loop NTPases, while in Rossmanns it binds the nucleotide's ri

138 sly unrecognized, widespread class of P-loop NTPases.

139 consistent with their roles in other P-loop NTPases.

140 cleotide binding fold typical for the P-loop NTPases.

141 op motif, constitute a superfamily of P-loop NTPases.

142 y consistent with the biochemistry of P-loop NTPases.

143 hermore, PPi is an inhibitor for the Tm-MazG NTPase activity.

144 e to Mg.ATP, they increased the rates and Me.NTPase activity of cross-linked acto-S1 and the fast com

145 The rates of force recovery and Me.NTPase activity were less than for Mg.ATP (by 40-80% and

146 Actomyosin-Subfragment 1 (acto-S1) Me.NTPase activity and Me.NDP release were monitored under

147 Unregulated actin-activated Mg-NTPase rates and actin sliding speed linearly increased

148 fsR-like transcription regulators) and NACHT NTPases (e.g. NAIP, TLP1, Het-E-1) that have been studie

149 Here, we show that DFCP1 is a novel NTPase that regulates free fatty acid metabolism.

150 The NS5 stimulation of NS3 NTPase was dose-dependent until an equimolar ratio was r

151 Therefore, the effect of NS5 on the NS3 NTPase activity was examined.

152 The results show that NS5 stimulated the NS3 NTPase and RTPase activities.

153 rotease, the NS3-4A serine protease, the NS3 NTPase/helicase, and the NS5B polymerase.

154 in at the P3 position for the NS1/2-3 (Nterm/NTPase) site confers significant influence on enzyme cat

155 The nuclear NTPase activity was not inhibited by vanadate, oligomyci

156 consistently found in the P-loop of numerous NTPase domains, where it stabilizes the substrate-bindin

157 Accumulation of NTPase mRNA in etiolated seedlings is stimulated by brie

158 e of the enzyme, a significant activation of NTPase activity was observed.

159 e of the enzyme, a significant activation of NTPase activity was observed.

160 Comparative analysis of NTPase and helicase activities of wild type nsP2 with en

161 Thus, the RNA loading and tight coupling of NTPase activity with RNA translocation in 8 P4 is due to

162 n synthesized and screened for inhibition of NTPase/helicase of the West Nile Virus (WNV).

163 atic reduction in the steady-state levels of NTPase.

164 ndings, suggest either that a single type of NTPase in cores is strongly influenced by two different

165 or that cores contain two different types of NTPase influenced by the two proteins.

166 nt Pdr5 is attributable to the uncoupling of NTPase activity and transport.

167 been synthesized as potential inhibitors of NTPases/helicases of Flaviviridae, including the West Ni

168 (R1) of BceSIV contains conserved motifs of NTPases and DNA helicases.

169 s not reported before in this superfamily of NTPases.

170 e full NS3-NS4A complex demonstrated optimal NTPase activity between pH 7.5 and 8.5.

171 5.7 kDa, which we designated p5.6, p32, p39 (NTPase), p30, p13 (VPg), and p76 (Pro-Pol), respectively

172 hree further highly divergent, cystoviral P4 NTPases (from 6, 8 and 13).

173 ic trees constructed for the NS polyprotein, NTPase, protease, polymerase, and capsid protein sequenc

174 ins needed for viroplasm assembly, possesses NTPase, RNA-binding, and helix-unwinding activities.

175 as for Maf, the structure of this predicted NTPase was determined as part of a structural genomics p

176 includes several other groups of (predicted) NTPase domains from diverse signaling and transcription

177 Surprisingly, this promiscuous NTPase displayed a canonical NFeoB G-protein fold like G

178 unctional enzyme possessing serine protease, NTPase, and RNA unwinding activities that are required f

179 ne of these, EpsE, is a cytoplasmic putative NTPase essential for the functioning of the Eps system a

180 or precisely classifying and naming putative NTPase genes based on phylogeny.

181 mily of the family encompassing all putative NTPases of type IV secretion systems.

182 tein, a member of a large family of putative NTPases from type II and IV secretion systems.

183 members of the PulE superfamily of putative NTPases that have extensive sequence similarity and prob

184 dA-like genes to those encoding the putative NTPases of type II/IV secretion, we used a phylogenetic

185 ucleoside triphosphate pyrophosphohydrolase (NTPase) and pyrophosphatase activities.

186 Ring NTPases of the ASCE superfamily perform a variety of cel

187 Ring NTPases represent a large and diverse group of proteins

188 nct subfamily of potential type IV secretion NTPase genes.

189 e hexameric rings of other type IV secretion NTPases.

190 binding was observed in many, and sequential NTPase catalysis has been observed in two proteins, gp4

191 protein BAG1 and a novel bradyzoite-specific NTPase during bradyzoite development were fine mapped to

192 sed a domain structure that included a STAND NTPase paired with a series of tetratricopeptide repeats

193 containing the common ancestor of the STAND NTPase domain of R-proteins and NLRs.

194 STAND NTPases represent a novel paradigm in signal transductio

195 n of the archaeal families, almost all STAND NTPases are multidomain proteins containing three or mor

196 Transfer of genes for STAND NTPases from bacteria to eukaryotes on several occasions

197 AAA+ ATPases, it can be predicted that STAND NTPases use the C-terminal helical bundle as a "lever" t

198 The STAND NTPases are most abundant in developmentally and organiz

199 aining the last common ancestor of the STAND NTPases of plant R-proteins and animal NLRs (and, by ext

200 Focusing on the STAND NTPases of plant R-proteins, animal NLRs, and their homo

201 A, HET-E, and TEP1) subfamilies of the STAND NTPases, we analyzed the phylogenetic distribution of th

202 but was not essential for its 40S-stimulated NTPase activity and function in initiation.

203 to 40S subunits and possesses 40S-stimulated NTPase activity essential for its function.

204 to E1, all NTPs tested support K+-stimulated NTPase activity and H+ pumping up to 30-50% of that with

205 -specific PTs by virtue of its PT-stimulated NTPase activity to exert its anti-phage activity, and (2

206 uired for serine protease and RNA-stimulated NTPase activities map within the region between amino ac

207 The RNA-stimulated NTPase activity was significantly affected by deletion o

208 otease activity, a C-terminal RNA-stimulated NTPase activity, and an RNA helicase activity.

209 ays an important role for the RNA-stimulated NTPase activity.

210 gion of NS3 (NS3hel) exhibits RNA-stimulated NTPase and helicase activity, while the N-terminal serin

211 ental effect on the basal and RNA-stimulated NTPase as well as RNA helicase activities.

212 RNA replication factors: 1a has a C-terminal NTPase/helicase-like domain, and 2a(pol) has a central p

213 e domain structure, comprising an N-terminal NTPase domain and a C-terminal DUF1998 domain (containin

214 PrrCs consist of two domains: an N-terminal NTPase module related to the ABC family and a distinctiv

215 We conclude that NTPase-dependent binding of LGP2 to internal dsRNA sites

216 essential parasite function and suggest that NTPase may have more than one function in vivo.

217 The NTPase activity of this component, before and after sepa

218 The NTPase activity was necessary, but not sufficient, to su

219 The NTPase activity was not stimulated by single-stranded nu

220 The NTPase activity with deoxyribonucleoside triphosphates a

221 The NTPase as it occurs with the polymerase displays cleavag

222 The NTPase can be exploited to screen in vitro for inhibitor

223 The NTPase was stimulated more than 50% by red light, and th

224 ion by the polymerase and of cleavage by the NTPase, operating on the same substrate pool.

225 s moiety of the DExH-box serve to couple the NTPase and helicase activities.

226 en infected cells were treated with DTT, the NTPase was activated in a dose-response fashion, as asse

227 Hence the NTPase activity of NSP2 probably has a role subsequent t

228 Overexpressing PrrCs with mutations in the NTPase active site ameliorated the toxicity of wild-type

229 Significant decreases in the NTPase activity and concomitant increases in the pyropho

230 econdary binding site that is located in the NTPase domain (Domain II) of NS3.

231 , we identified 22 essential residues in the NTPase domain and 11 in the nuclease domain.

232 blotting with pea genomic DNA indicates the NTPase is likely to be encoded by a single gene.

233 bA bind to synthetase, but do not induce the NTPase activity.

234 binding to RNA substrate and modulating the NTPase/RNA helicase and RTPase activities of NS3.

235 f its Walker A nucleotide-binding motif, the NTPase activity of TssM and its role in T6SS remain obsc

236 In addition to hydrolyzing NTPs the NTPase could also hydrolyze the 5'-terminal phosphate fr

237 aluation of the biological importance of the NTPase activity of NSP2 by transient expression in mamma

238 Potential implications of the NTPase activity of PilT in pilus retraction are discusse

239 rtantly, abrogated the responsiveness of the NTPase activity to stimulation, which abolished DHX29's

240 activity in vitro, and thus the role of the NTPase domain in cluster biogenesis has remained uncerta

241 dd significantly to our understanding of the NTPase domain of FeoB and its role in Feo function.

242 kelihood methods to infer a phylogeny of the NTPase domains of R-proteins, and reconstructed the doma

243 ntingent on head-to-tail dimerization of the NTPase domains to form two composite NTP phosphohydrolas

244 indicate that the cleavage preference of the NTPase for noncomplementary NTPs is not part of a mechan

245 has led to proposals for involvement of the NTPase in transcriptional error prevention.

246 unctions of the conserved amino acids of the NTPase motifs are context dependent.

247 e that the oxidation/reduction status of the NTPase, the only parasite dense granule protein that con

248 to examine the RNA helicase activity of the NTPase/helicase domain of HEV, the region (amino acids 9

249 xamine the effects of polynucleotides on the NTPase, helicase, and protease activities.

250 he pilus filament is extruded, and PilT, the NTPase that mediates pilin disassembly and retraction.

251 We have reexamined the NTPase activity of Nbp35, Cfd1, and their complex.

252 res the centromere-binding protein SopB, the NTPase SopA and the sopC centromere.

253 Northern blot analysis shows that the NTPase MRNA is strongly expressed in etiolated plumules,

254 These results indicate that the NTPase/helicase activities are essential functions of ML

255 In addition to the NTPase domain, these proteins typically contain DNA-bind

256 terminal helical bundle that is fused to the NTPase domain.

257 that IgG against human lamin C binds to the NTPase in immunoblots.

258 motif III (SAT) mutations that uncouple the NTPase and helicase activities.

259 hyperphosphorylation when combined with the NTPase and helix-destabilizing protein NSP2.

260 merase, which then does not compete with the NTPase for the substrate pool.

261 helicases, plays an important role in their NTPase cycle.

262 n, myosin and G proteins indicate that these NTPases may have a similar strategy of changing conforma

263 spectroscopic approaches, we show that this NTPase domain can dimerize and can hydrolyze both ATP an

264 f 15 genes in the operon and has homology to NTPases of type IV secretion systems.

265 sed an associated nucleoside triphosphatase (NTPase) activity in vitro, which in the presence of Mg(2

266 a Mg2+-dependent nucleoside triphosphatase (NTPase) activity, and is a component of replication inte

267 es 40S-stimulated nucleoside triphosphatase (NTPase) activity.

268 the protein, and nucleoside triphosphatase (NTPase) and helicase activities reside in the remaining

269 Here, by nucleoside triphosphatase (NTPase) assay and comparisons of six high-resolution (2.

270 ed in an in vitro nucleoside triphosphatase (NTPase) assay to show that UL84 has NTPase activity, pre

271 The LEF-4 nucleoside triphosphatase (NTPase) is activated by manganese or cobalt but not by m

272 Helicase/nucleoside triphosphatase (NTPase) motifs have been identified in many RNA virus ge

273 A nucleoside triphosphatase (NTPase) present in highly purified preparations of pea n

274 ing loop (P-loop) nucleoside triphosphatase (NTPase) superfamily.

275 encoding a 47 kDa nucleoside triphosphatase (NTPase) that is associated with the chromatin of pea nuc

276 ral proteins with nucleoside triphosphatase (NTPase)/helicase motifs or activities.

277 an RNA-stimulated nucleoside triphosphatase (NTPase)/RNA helicase and a 5'-RNA triphosphatase (RTPase

278 al RNA-stimulated nucleoside triphosphatase (NTPase)/RNA helicases.

279 und that SegC has nucleotide triphosphatase (NTPase) activity.

280 ciated nucleoside and 5' RNA triphosphatase (NTPase/RTPase) activities that are mediated by a conserv

281 A second S. cerevisiae RNA triphosphatase/NTPase (named Cth1p) containing motifs A, B, and C was i

282 cleotide binding nucleoside triphosphatases (NTPases) or nucleoside triphosphate (NTP) binding protei

283 c acid-dependent nucleoside triphosphatases (NTPases), which is defined by the presence of several co

284 esembling P-loop nucleotide triphosphatases (NTPases) instead.

285 ly of metal-dependent RNA 5'-triphosphatases/NTPases encoded by fungi and DNA viruses; the family is

286 e the hydrolysis of nucleoside triphosphate (NTPase) to nucleic acid unwinding.

287 tive and inactive telomerase RNPs, while two NTPase proteins associate preferentially with active enz

288 he data presented here suggest that the two "NTPase" catalytic sites in terminase holoenzyme communic

289 translocation by a multi-subunit, ring-type NTPase.

290 n vitro is regulated by a previously unknown NTPase domain.

291 se combine thresholding mechanisms utilizing NTPase chaperones (the MoxR-vWA couple), GTPases and pro

292 ailed to show any activity against the viral NTPase reaction even up to 500 muM.

293 itional allosteric binding site on the viral NTPases/helicases that can be occupied by nucleoside/nuc

294 helicase and ATPase activities of the viral NTPases/helicases.

295 us replication, insofar as mutants for which NTPase was uncoupled from unwinding (H299A, T326A, and T

296 RNA polymerase harbor a 70 kDa protein with NTPase (beta-gamma cleavage) activity that is not a reco