ライフサイエンスコーパス: New World arenavirus

1 tive against LASV, but not those specific to New World arenaviruses.

2 stinct from the one used by human-pathogenic New World arenaviruses.

3 ns, including LFV, Mobala virus, and clade C New World arenaviruses.

4 uence is highly conserved among both Old and New World arenaviruses.

5 ic choriomeningitis virus (LCMV) and clade C New World arenaviruses.

6 entical or similar sites utilized in several New World arenaviruses.

7 receptor usage and GP1 sequences of Old and New World arenaviruses.

8 nent of the GPC spike from Old World but not New World arenaviruses adopts a distinct, pH-independent

9 tically divergent from the classical Old and New World arenaviruses and also differ substantially fro

10 Our data show that these New World arenaviruses are specifically adapted to the T

11 cology and molecular and cellular biology of New World arenaviruses, as well as a discussion of the c

12 rther classified into OW (Old World) and NW (New World) arenaviruses based on their antigenicity, phy

13 All pathogenic New World arenaviruses bind to a common region of the ap

14 at the Z protein of Tacaribe virus (TACV), a New World arenavirus, buds efficiently from cells despit

15 e cycle can be specifically inhibited in the New World arenaviruses by the small-molecule compound ST

16 NV antisera against MACV.IMPORTANCE Multiple New World arenaviruses can cause severe disease in human

17 At least five New World arenaviruses cause severe human hemorrhagic fe

18 sative agent of AHF is Junin virus (JUNV); a New World arenavirus classified as a National Institute

19 sative agent of AHF is Junin virus (JUNV); a New World arenavirus classified as an NIAID/CDC category

20 Clade B of the New World arenaviruses contains both pathogenic and nonp

21 ntal approach to assess the compatibility of New World arenaviruses, endemic in rodents, with the hos

22 bundle and presents direct verification that New World arenaviruses exhibit class I viral membrane fu

23 The emergence of Old and New World arenaviruses from rodent reservoirs persistent

24 Transmission of hemorrhagic fever New World arenaviruses from their rodent reservoirs to h

25 tivity against pseudoviruses bearing Old and New World arenavirus glycoproteins but not against virus

26 r and thus superinfection exclusion, whether New World arenaviruses have evolved such a mechanism rem

27 stroglycan as a cell-surface receptor, while New World arenaviruses hijack transferrin receptor.

28 hogenic Lassa fever virus (LFV), and clade C New World arenaviruses is alpha-dystroglycan (alpha-DG),

29 ccine that protects against a broad range of New World arenaviruses is desirable for purposes of simp

30 The situation with New World arenaviruses is less clear: previous studies d

31 The Junin virus, a member of the New World arenaviruses, is endemic to the pampas grassla

32 SVGP resembled those of the human-pathogenic New World arenavirus Junin virus (JUNV) and other envelo

33 The New World arenavirus Junin virus (JUNV) is the causative

34 The New World arenavirus Junin virus (JUNV) is the causative

35 ocytic choriomeningitis virus (LCMV) and the New World arenavirus Junin virus (JUNV) strain Candid #1

36 n-mediated endocytosis, which is used by the New World arenavirus Junin virus, and pathways used by o

37 itical for cellular binding and entry of the New World arenaviruses Junin and Tacaribe virus, suggest

38 The New World arenaviruses, Junin, Machupo, Guanarito, Sabia

39 Compared to the New World arenaviruses, Lassa and the other Old World ar

40 und that neutralizing antibodies against two New World arenaviruses, Machupo virus (MACV) and Junin v

41 n humans, acts by blocking hemorrhagic fever New World arenavirus (NWA) entry into cells.

42 Several clade B New World arenaviruses (NWAs) can cause severe and often

43 lpha-DG as a major receptor, whereas, of the New World arenaviruses, only clade C viruses (i.e., Oliv

44 Infection of guinea pigs with the New World arenavirus Pichinde virus (PICV) has been used

45 aviruses LFV, Mopeia virus, and LCMV and the New World arenavirus Sabia virus bound at high affinity

46 omparison, we noted that eight Old World and New World arenaviruses share several amino acids with th

47 g of a panel of pathogenic and nonpathogenic New World arenaviruses, suggesting that GPC cleavage rep

48 This study uses the New World arenavirus Tacaribe, a neurotropic pathogen th

49 nt of Bolivian hemorrhagic fever (BHF), is a New World arenavirus that was first isolated in Bolivia

50 The ability of a New World arenavirus to use human TfR1 is absolutely pre

51 humans likely occurs because the pathogenic New World arenaviruses use human transferrin receptor 1

52 es activity against viruses with the Old and New World arenavirus viral glycoprotein complex but not

53 initial studies, several additional Old and New World arenaviruses were screened for entry into mous