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1 sed inactivator for the design of cytochrome P450 inhibitors.
2 nhibitors, which tend to be poorly selective P450 inhibitors.
3                               The cytochrome P450 inhibitor 1-aminobenzotriazole blocked the VPA-stim
4 s completely abolished by treatment with the P450 inhibitor 1-aminobenzotriazole.
5 d was coadministered with the pan-cytochrome P450 inhibitor 1-aminobenzotriazole.
6 carbonitrile, and clofibrate) or the general P450 inhibitor 1-aminobenztriazole; induction of P4501A,
7                               The cytochrome P450 inhibitor 1-benzylimidazole did not affect SAC, SBC
8 inhibitor) nor ethoxyresorufin (a cytochrome P450 inhibitor) altered the 86Rb uptake response to PDBu
9  response were ameliorated by the cytochrome P450 inhibitor aminobenzotriazole.
10 he tightest-binding azaheterocycles found in P450 inhibitors and could offer new avenues for inhibito
11 be required for toxicity (no protection with P450 inhibitors and no detectable inorganic fluoride rel
12 actions, the development of isoform-specific P450 inhibitors, and the engineering of novel oxidative
13 -octadecynoic acid (17-ODYA, 10(-5) mol/L; a P450 inhibitor) attenuated maximal dilation to AA (49+/-
14            Azoles are frequently nonspecific P450 inhibitors because they coordinate the catalytic he
15 s was inhibited by fluvoxamine, a cytochrome P450 inhibitor, but not by 15- or 5-LOX inhibitors, sugg
16 of intracerebral (ic) microinjections of the P450 inhibitor CC12 were determined on morphine antinoci
17 rats injected with anti-Fx1A, the cytochrome P450 inhibitor cimetidine blocked an increase in catalyt
18 3A4 bind inhibitors rapidly and two distinct P450-inhibitor complexes exist en route to the final enz
19 xidase, and aminobenzotriazole, a cytochrome P450 inhibitor, decreased free radical formation from fo
20 onazole (10(-5) mol/L, a chemically distinct P450 inhibitor) further reduced the dilation to AA in th
21  does the fact that polycyclic azoles (known P450 inhibitors) have potent anti-mycobacterial effects.
22 ) if weight <40 kg) with a strong cytochrome P450 inhibitor, in 28-day cycles.
23 llular dialysis with 2 mM cAMP abolished the P450 inhibitor-induced suppression of ICa.
24 0.8 microM) compared with the broad spectrum P450 inhibitor ketoconazole and the retinoid mimetic R11
25                              The azole-based P450 inhibitor ketoconazole is used to treat fungal infe
26                 Pretreatment with cytochrome P450 inhibitor, ketoconazole, reduced anemia by 96.8 +/-
27 concentration-dependent and inhibited by the P450 inhibitors, ketoconazole and clotrimazole with IC(5
28 bitor diphenyleneiodonium chloride or by the P450 inhibitor metyrapone, providing evidence of its dep
29 HPETE, and pretreatment with the cyctochrome P450 inhibitor, miconazole, blocked the formation of the
30          However, synergist assays using the P450 inhibitor PBO, or the esterase inhibitor TPP result
31                                              P450 inhibitor piperonyl butoxide (PBO) significantly en
32 stration of nirmatrelvir with the cytochrome P450 inhibitor ritonavir.
33 biosynthesis, and clotrimazole, a cytochrome P450 inhibitor, significantly reduced ICa in both wild-t
34 , econazole and miconazole, which are potent P450 inhibitors, significantly suppressed cardiac ICa.
35                               The cytochrome P450 inhibitors, SKF 525A and miconazole, significantly
36 ): (1) Control, (2) l-NAME, (3) a cytochrome P450 inhibitor, sulfaphenazole, and (4) sulfaphenazole +
37 entified six triazole fungicides, all fungal P450 inhibitors, that dock in the catalytic site.