戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 robe derived from the kinase domain of a rat PAK kinase.
2 self, as well interacting with its effector, Pak kinase.
3 k3, a member of the serine/threonine group I PAK kinases.
4  PF kinases, whose closest relatives are the PAK kinases.
5 essential cell cycle kinases like Aurora and PAK kinases.
6 mologous to mammalian p21-activated kinases (PAKs) (kinases activated by the rho-class GTPase Rac or
7                              We investigated Pak kinase activation in more detail to gain insight int
8                                              PAK kinase activity and subcellular distribution are tig
9                               This effect on PAK kinase activity closely parallels Nischarin's abilit
10                                Inhibition of Pak kinase activity dramatically decreased phosphorylati
11 Pak substrate and further suggest a role for Pak kinase activity in atypical MAPK signaling.
12  showed that selective inhibition of class I Pak kinase activity in cells promoted increased nuclear
13                      These results show that PAK kinase activity is required for bacteria-induced nuc
14 sion of this domain did not, indicating that PAK kinase activity is required for normal growth factor
15 n of PAK1 activity was dependent upon intact PAK kinase activity, as indicated by studies with a kina
16 l adhesions in these cells is independent of PAK kinase activity, NCK binding, or GTPase binding, but
17 w that the closely related Cool-2 stimulates Pak kinase activity.
18 , these results elucidate the specificity of Pak kinases and illustrate a general method for the iden
19                                              Pak kinases are a family of serine/threonine protein kin
20    Because the Rho family of GTPases and the Pak kinases are implicated in actin polymerization, the
21  In conclusion, our studies demonstrate that PAK kinases are necessary for polar growth during mating
22                                              Pak kinases are thought to play critical roles in cell m
23 hosphorylation of the activation loop of one PAK kinase domain by another, but little is known about
24 nd that the Cdc42 GTPase and a member of the PAK kinase family called Cla4 both function in the pathw
25 ious studies demonstrating the role of Ste20/PAK kinases in heterotrimeric G protein signaling, sugge
26 ther investigated the involvement of group I PAK kinases in HIV using siRNA.
27 ak) function; however, the specific role for Pak kinases in megakaryocyte biology remains elusive.
28 ther investigate the possible involvement of PAK kinases in tumorigenesis, we analyzed the expression
29 ion of this individual Nck SH3 domain, or of Pak kinase itself, to the membrane results in activation
30 actor Nef has been shown to associate with a PAK kinase, leading to enhanced viral production; howeve
31 As, designated PAK-1 and PAK-3, encode mouse PAK kinases of 545 and 544 amino acids, respectively.
32 otentiating adhesion-dependent activation of PAK kinase (p < 0.001), a Rac effector that associates w
33                    Two p21-activated kinase (PAK) kinases, Pak1 and Ste20, are required for both mati
34  between cardiomyocytes through the Arhgef7b/Pak kinase pathway in order to guide atrioventricular ca
35                  Comparison of the two mouse PAK kinases revealed that the proteins show 87% amino ac
36   A second genetically separable function of Pak kinase signaling controls muscle membrane specializa
37                     Mrs6 interacted with the PAK kinase Ste20 and MAPKK Ste7 by two-hybrid analysis.
38            These subunits signal through the PAK kinase Ste20 to activate a mitogen-activated protein
39 hose components include Ras proteins and the PAK kinase Ste20, allows the human fungal pathogen Crypt
40 SH2/SH3-containing adaptor protein Nck binds Pak kinase through its second SH3 domain.
41 which is responsible for the localization of PAK kinases to focal complexes in the cell, is mediated
42  defects and conversely, overexpression of a PAK kinase was able to rescue the loss of RhoU cardiac d
43                           Two cDNAs encoding PAK kinases were isolated from a mouse embryo library by
44                                              PAK kinases were unique in having exceptionally strong A
45 ct of Rac or Cdc42 can be substituted by the Pak kinase, which is a direct downstream target of Rac/C
46  is a brain-specific isoform of the group II Pak kinases whose substrates and roles within the centra