ライフサイエンスコーパス: PCN

1 PCN also demonstrated the poorest functional properties

2 PCN and IMF had the highest and lowest extent of surface

3 PCN assessment was based on ACR 2017 recommendations.

4 PCN has been shown to interfere with a variety of cellul

5 PCN incidence increased with age, but due to the rarity

6 PCN risk was 1.8-fold increased relative to the general

7 PCN risk was especially high in recipients who were Epst

8 PCN-128W exhibits interesting piezofluorochromic behavio

9 PCN-134 demonstrates high porosity (N2 uptake of 717 cm(

10 PCN-521 has the largest BET surface area (3411 m(2) g(-1

11 PCN-600 exhibits a one-dimensional channel as large as 3

12 PCN-600(Fe) has been demonstrated as an effective peroxi

13 PCN-700, a Zr-MOF with eight-connected Zr6O4(OH)8(H2O)4

14 PCN-777 exhibits the largest cage size of 3.8 nm and the

15 PCN-dependent loss of mineral density is observed in the

16 PCN-mediated goblet cell hyperplasia and metaplasia requ

17 PCNs smaller than 5 mm at baseline did not demonstrate g

18 egional cancer registries, we identified 140 PCNs in 202 600 recipients (1987-2009).

19 5% of cell migration into Gtn-HPA/SDF-1alpha-PCN hydrogels involved MMP-2, 3, and 9, respectively, de

20 d their neuronal progeny, Gtn-HPA/SDF-1alpha-PCN hydrogels promoted chemotactic recruitment to enhanc

21 Overall, Gtn-HPA/SDF-1alpha-PCN hydrogels prove to be promising biomaterials for inj

22 ked with 0.85-0.95 mM HO, Gtn-HPA/SDF-1alpha-PCN hydrogels provided optimally permissive structural s

23 ic metal-organic frameworks (MOFs), PCN-228, PCN-229, and PCN-230, with ftw-a topology were synthesiz

24 A series of flexible MOFs (PCN-605, PCN-606, and PCN-700) are synthesized and applied to rev

25 tions of the expression plasmid pA-EGFP_B, a PCN from 1 to 64 could be accurately detected.

26 ontinuously treated with mouse PXR activator PCN to evaluate the hypothesis that induction of the Cyp

27 expression of Oatp2, rats were administered PCN, livers were extracted at various times, and Oatp2 e

28 with increased Mrp2 protein synthesis after PCN treatment.

29 Among PCNs smaller than 5 mm at baseline, 100% of PCNs at 3-ye

30 Among PCNs, Intraductal Papillary Mucinous Neoplasms (IPMNs) a

31 en designed and synthesized from NU-1000 and PCN-222/MOF-545, respectively, and phosphate-terminated

32 ic frameworks (Zr-MOFs), namely, PCN-133 and PCN-134.

33 nic frameworks (MOFs), PCN-228, PCN-229, and PCN-230, with ftw-a topology were synthesized using the

34 table, non-interpenetrated MOFs, PCN-521 and PCN-523, were synthesized by a symmetry-guided strategy.

35 These data suggest that MOF-525 and PCN-224 are the kinetic products while PCN-222 is the th

36 ays, while the contribution from MOF-525 and PCN-224 decreased.

37 3 (shp topology), in addition to MOF-525 and PCN-224.

38 for the catenation isomer pairs of PCN-6 and PCN-6' (both have the formula of Cu(3)(TATB)(2), where T

39 ries of flexible MOFs (PCN-605, PCN-606, and PCN-700) are synthesized and applied to reversible bromi

40 acity, are demonstrated: SNU-70, UMCM-9, and PCN-610/NU-100.

41 DP and PCN form a bilateral column of cells extending ventrolat

42 yrido-[3,2-d:2',3'-f]-quinoxaline (dpq), and PCN = tris-(2-cyanoethyl)phosphine, have been synthetize

43 TrfA1 enhanced transformation efficiency and PCN.

44 ganic frameworks (MOFs), PCN-426-Fe(III) and PCN-426-Cr(III), have been synthesized through a strateg

45 the structures range from 2.5 to 3.8 nm, and PCN-229 demonstrates the highest porosity and BET surfac

46 rved from livers of rats treated with PB and PCN, in which PCN caused a robust elevation of Oatp2 mRN

47 Oatp2, but not Oatp1, is inducible by PB and PCN, which imparts the increased capacity of the liver t

48 f 14C-labeled Mrp2 in control, pregnant, and PCN-treated rats were 27, 36, and 22 h, respectively, an

49 regulation of Mrp2 in control, pregnant, and PCN-treated rats.

50 allergy evaluation with history-appropriate PCN skin testing: if skin test negative, give cefazolin

51 The MOFs studied are PCN-222, MOF-525, and NU-902, which are based on the csq

52 ructed a metal-organic framework, denoted as PCN-128W, starting from chromophoric linker and zirconiu

53 Compared with the bare PCN and HP, the optimized PCN@HP hybrid exhibited a sign

54 c and basic units in the mesoporous RE-based PCN-905-SO(2) allows for efficient cascade catalytic tra

55 ACR criteria) was examined by using baseline PCN size, among other factors.

56 For groups in which baseline PCN size was smaller than 5 mm, 5-14 mm, 15-25 mm, and l

57 The correlation between PCN times and ADHD symptom ratings suggests that this br

58 that the strong electronic coupling between PCN and [001]-oriented HP nanorods gave rise to the enha

59 urface modification, the interaction between PCN-777 and different guests can be varied to realize ef

60 Despite low cross-reactivity between PCN and later-generation cephalosporins, some providers

61 s of a low allergic cross-reactivity between PCN and later-generation cephalosporins.

62 and 2 (3.8%) had reported allergies to both PCN and cephalosporin antibiotics.

63 PXR activation by PCN in high-fat diet fed mice also increases expression

64 anscriptional regulators that are altered by PCN and LPS, our study provides novel insights into the

65 ressed by LPS treatment and were enhanced by PCN treatment.

66 ral pH value, singlet oxygen is generated by PCN-222/MOF-545 using an inexpensive and commercially av

67 he molecular mechanism of oatp2 induction by PCN, rat oatp2 gene was cloned.

68 quired for maximal induction of rat oatp2 by PCN.

69 I) in aqueous solution was also performed by PCN-134-22%TCPP which exhibits excellent catalytic activ

70 The singlet oxygen produced by PCN-222/MOF-545 selectively oxidizes CEES to the compara

71 r pathways that are enriched or repressed by PCN and LPS based on a gene set enrichment analysis.

72 CLE1, a multidomain CLE effector secreted by PCN during infection, is a 12-amino acid arabinosylated

73 Induction of UGT1A1 by PCN and TCDD is believed to be highly dependent upon glu

74 R agonist pregnenolone-16alpha-carbonitrile (PCN) activated Akr1b7 gene expression, whereas the effec

75 R ligands pregnenolone-16alpha-carbonitrile (PCN) and dexamethasone increased p-glycoprotein expressi

76 activator pregnenolone-16alpha-carbonitrile (PCN) and was subsequently downregulated using lipopolysa

77 activator pregnenolone 16alpha-carbonitrile (PCN) down-regulated the mRNA levels of carnitine palmito

78 of PXR by pregnenolone 16alpha-carbonitrile (PCN) in AKR/J mice can prevent the development of high-f

79 PXR with pregnenolone 16alpha-carbonitrile (PCN) in wild-type mice, which greatly reduced the severi

80 (PB) and pregnenolone-16alpha-carbonitrile (PCN) occurs via increased hepatic expression of Oatp1 an

81 activator pregnenolone-16alpha-carbonitrile (PCN) or the Ah receptor ligand 2,3,7,8-tetrachlorodibenz

82 rats with pregnenolone-16alpha-carbonitrile (PCN), a ligand for the rodent pregnane X receptor (PXR),

83 regnen-3beta-ol-20-one-16alpha-carbonitrile (PCN), followed by an increase in Cyp3a11 mRNA.

84 s such as pregnenolone 16alpha-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression

85 nant, and pregnenolone-16alpha-carbonitrile (PCN)-treated rats using in vivo metabolic-labeling studi

86 regnen-3beta-ol-20-one-16alpha-carbonitrile (PCN, 25 mg/kg) or its vehicle over 7 d.

87 regnen-3beta-ol-20-one-16alpha-carbonitrile (PCN, 25 mg/kg) or its vehicle over 7 days.

88 nd to be substantially stronger in catenated PCN-6 than in noncatenated PCN-6', leading to much highe

89 Cationic PCN-223(Fe) formed by postsynthetic treatment is an exce

90 uch lower PCN (</=1) than fluorescent cells (PCN of up to 5) under standard conditions.

91 ected NU-902 (scu topology) and 12-connected PCN-223 (shp topology), in addition to MOF-525 and PCN-2

92 assuming no defects) MOF-525 and 6-connected PCN-224, possessing ftw and she topologies, respectively

93 ure was raised to 145 degrees C, 8-connected PCN-222 (csq topology) was found, with a possible concur

94 With its extremely high connectivity, PCN-223 shows high stability in aqueous solutions with a

95 The two most effective complexes [HB(pz)3]Cu(PCN), 1, and [HB(pz)3]Cu(PTA), 2, showed selectivity tow

96 ge of Radiology (ACR) recommendations define PCN measurement and growth for different categories base

97 se To assess growth of incidentally detected PCNs on long-term imaging follow-up using revised ACR re

98 DP-PCN neurons show an oscillatory pattern of activity, fir

99 ons only fire during the silent period of DP-PCN neurons, suggesting that they provide recurrent inhi

100 During "scallops", only DP-PCN neurons with high baseline firing rates increase the

101 ventroposterior nucleus (VPd) projects to DP-PCN and receives input from the electric organ corollary

102 that they provide recurrent inhibition to DP-PCN.

103 extracellularly from single units within DP-PCN and VPd and correlated their activity patterns with

104 cells along the ventral edge projects to DP/PCN and to CN, whereas a dorsal group of small, ovoid ce

105 l group of small, ovoid cells projects to DP/PCN but not to CN.

106 The primary input to DP/PCN is from VP, which is identified as having two distin

107 taxa, suggest that modifiable feedback to DP/PCN plays a critical role in electromotor control and th

108 [CuCl(phen)(PCN)].DMF (5.DMF) and [CuBr(dpq)(PCN)].2DMF (10.2DMF).

109 The most effective complex, [CuCl(dpq)(PCN)] (9), exhibited nanomolar cytotoxicity toward both

110 ycholic acid, and lithocholic acid by either PCN or TCDD in small intestine from Tg-UGT1 mice corresp

111 nt with suspected bacterial endophthalmitis, PCN allergy may not be an absolute contraindication to i

112 As a representative example, PCN-230, constructed with the most extended porphyrinic

113 f-PCN(DXR) can readily discriminate FR-positive tumor cell

114 ulting folate-conjugated, DXR-loaded PCNs (f-PCN(DXR)) demonstrated enhanced potency to folate recept

115 and pH-sensitive drug-releasing triggers, f-PCN(DXR) was fifty-times more potent than the untargeted

116 These two subpopulations were sorted for PCN determination with ddPCR.

117 at 298 K/50 bar, respectively, and that for PCN-6' is 42 mg/g (4.0 wt %) at 77 K/50 bar or 4.0 mg/g

118 much higher than the corresponding value for PCN-14 (157 cm(3) (STP) cm(-3) ).

119 the highest amounts were stored in soil for PCNs, PBDEs, and PCBs while highest PAH amounts were sto

120 of the water-stable metal-organic framework PCN-200 provides a new route to low-energy selective CO(

121 A microporous metal-organic framework, PCN-14, based on an anthracene derivative, 5,5'-(9,10-an

122 Specifically, two metal-organic frameworks, PCN-224 and ZIF-412, which contain two and three differe

123 n of the exchange system, the functionalized PCN-333(Cr), N3-PCN-333(Cr) shows well maintained crysta

124 nic zirconium MOFs, obtaining pure hexagonal PCN-223 and cubic MOF-525 phases in 20-60 min of milling

125 A1 alone, again, generally elicited a higher PCN of an IncP1-beta replicon than strains expressing Tr

126 ells, TrfA1 maintained a 3- to 4-fold higher PCN than TrfA2 at the same TrfA concentrations, indicati

127 lasma cells generates a mouse model of human PCN that recapitulates some features of human multiple m

128 lls might lead to an improved model of human PCN, we generated Myc transgenics by inserting a single-

129 Importantly, PCN-6 exhibits a total hydrogen uptake of 95 mg/g (8.7 w

130 More importantly, PCN-134 tolerates the partial absence of auxiliary linke

131 robic alcohol oxidation reaction is built in PCN-700 through linker installation, which shows high ac

132 hermodynamic work of cohesion was highest in PCN and may have contributed to inadequate rehydration b

133 ncorporation of 35S into Mrp2 was highest in PCN-treated rats.

134 nally large pores ( approximately 5.5 nm) in PCN-333(Cr), a secondary functional moiety, Zn-TEPP with

135 oughly analyzed ligand exchange phenomena in PCN-333 and demonstrate that the extent of exchange can

136 amide effectively inhibits ROS production in PCNs induced by blood exposure or hemoglobin insult.

137 nd Methods This retrospective study included PCNs with baseline imaging performed between January 200

138 ransplantation is supported by the increased PCN risk in young EBV seronegative recipients and the pr

139 beta and dephosphorylated APC in the injured PCNs.

140 Interestingly, PCNs utilized FGF-2 found in situ to induce chemokinesis

141 y of functional groups are incorporated into PCN-333.

142 onalities can be sequentially installed into PCN-700.

143 the left anteromedial IPL (a-mIPL) and left PCN did signal strength decrease parametrically from non

144 We suggest that the left PCN may contribute a supporting visuospatial representat

145 the resulting folate-conjugated, DXR-loaded PCNs (f-PCN(DXR)) demonstrated enhanced potency to folat

146 th nonfluorescent cells showing a much lower PCN (</=1) than fluorescent cells (PCN of up to 5) under

147 ing metal organic framework (MOF) materials: PCN-14, UTSA-20, HKUST-1, Ni-MOF-74 (Ni-CPO-27), NU-111,

148 ze categories (subhazard ratio: 2.8 [5-14-mm PCN group], 3.4 [15-25-mm PCN group], and 2.7 [>25 mm gr

149 atio: 2.8 [5-14-mm PCN group], 3.4 [15-25-mm PCN group], and 2.7 [>25 mm group], as compared with the

150 7 [>25 mm group], as compared with the <5 mm PCN group; P < .05 for each) demonstrated association wi

151 he porphyrinic metal-organic framework (MOF) PCN-224 is metalated with Fe(II) to yield a 4-coordinate

152 A facile preparation of a mesoporous Cr-MOF, PCN-333(Cr) with functional group, has been demonstrated

153 A series of flexible MOFs (PCN-605, PCN-606, and PCN-700) are synthesized and appli

154 porphyrinic metal-organic frameworks (MOFs), PCN-228, PCN-229, and PCN-230, with ftw-a topology were

155 two robust metal-organic frameworks (MOFs), PCN-426-Fe(III) and PCN-426-Cr(III), have been synthesiz

156 Two stable, non-interpenetrated MOFs, PCN-521 and PCN-523, were synthesized by a symmetry-guid

157 Moreover, PCN-777 shows excellent stability in aqueous environment

158 plexes of the type [Cu(X)(N( intersection)N)(PCN)], 3-10, where X = Cl or Br, N( intersection)N = 2,2

159 e system, the functionalized PCN-333(Cr), N3-PCN-333(Cr) shows well maintained crystallinity, porosit

160 aining metal-organic framework (MOF), namely PCN-777, has been designed and synthesized.

161 mesoporous metalloporphyrin Fe-MOFs, namely PCN-600(M) (M = Mn, Fe, Co, Ni, Cu), have been synthesiz

162 ly stable MOFs with 3-D nanochannels, namely PCN-224 (no metal, Ni, Co, Fe), have been assembled with

163 we designed a flexible Zr-MOF system, namely PCN-700 series, for the realization of switchable cataly

164 metal-organic frameworks (Zr-MOFs), namely, PCN-133 and PCN-134.

165 with inherent missing linker sites, namely, PCN-700, was initially constructed under kinetic control

166 Modularly clickable polymer-caged nanobins (PCNs) were prepared from liposome templates using a drop

167 tosan polyelectrolyte complex nanoparticles (PCNs) that delivered stromal cell-derived factor-1alpha

168 ntly, DNA-modified porphyrinic MOF nanorods (PCN-222) were assembled into 2D superlattices and found

169 biphenyl (PCB), polychlorinated naphthalene (PCN), and polybrominated diphenyl ether (PBDE) congeners

170 few studies of polychlorinated naphthalenes (PCNs) for biota in polar regions and even fewer reports

171 henyls (PCBs), polychlorinated naphthalenes (PCNs), and polybrominated diphenyl ethers (PBDEs) were m

172 s and included polychlorinated naphthalenes (PCNs), polychlorinated dibenzofurans (PCDFs), chlorinate

173 ing: the posterior contralateral negativity (PCN) was used to index focal-attentional selection times

174 arasitic nematode, the potato cyst nematode (PCN) Globodera rostochiensis.

175 matodes, including the potato cyst nematode (PCN); however, the mechanistic details of this cross-kin

176 The potato cyst nematodes (PCNs) Globodera rostochiensis and Globodera pallida are

177 Potato cyst nematodes (PCNs), Globodera rostochiensis and G. pallida, cause imp

178 tal detection of pancreatic cystic neoplasm (PCN) has increased.

179 ent features of human plasma cell neoplasms (PCNs).

180 ave elevated risk for plasma cell neoplasms (PCNs, comprising multiple myeloma and plasmacytoma), but

181 Pancreatic cystic neoplasms (PCNs) are a highly prevalent disease of the pancreas.

182 ory of 15-25-mm pancreatic cystic neoplasms (PCNs) demonstrated the highest (3.1 times) likelihood of

183 emerging approach (Protein Contact network, PCN) based on the formalization of 3D structures as cont

184 nd in blood-induced primary cortical neuron (PCNs) cellular model of SAH in vitro.

185 al target, NQO1, in primary cortical neuron (PCNs).

186 rall spike rates of piriform cortex neurons (PCNs) were sensitive to the relative timing of activatio

187 Primary cortical neurons (PCNs) were subjected to oxygen glucose deprivation (OGD)

188 cessfully grown on polymeric carbon nitride (PCN) by a chemical vapor deposition strategy.

189 nger in catenated PCN-6 than in noncatenated PCN-6', leading to much higher H(2) uptake in the isomer

190 ) pneumococci, or penicillin-nonsusceptible (PCN-NS) pneumococci.

191 Carriage of COT-NS, but not PCN-NS, pneumococci also decreased (38%; P=.02), not onl

192 s from the mesencephalic precommand nucleus (PCN) and the adjacent thalamic dorsal posterior nucleus

193 receives inputs from the precommand nucleus (PCN) at the mesencephalic-diencephalic border and the ve

194 or the determination of plasmid copy number (PCN) are available, and most of them average the PCN of

195 ency of transformation, plasmid copy number (PCN), and plasmid stability were first compared between

196 ion assisted by the structural attributes of PCN-333 has been studied while maintaining the integrity

197 s confirmed ABCB1 induction in the brains of PCN-treated APP/PS1-21 mice with a concomitant decrease

198 s confirmed ABCB1 induction in the brains of PCN-treated APP/PS1-21 mice with a concomitant decrease

199 gnificantly, the expected usable capacity of PCN-6 is as high as 75 mg/g (or 41.9 g/L) at 77 K, if a

200 erall carriage of pneumococci or carriage of PCN-NS pneumococci.

201 However, the contributions of PCN during infection of bronchiectatic airways are not a

202 00 sorted cells for precise determination of PCN.

203 The beneficial effects of PCN treatment are seen with reduced lipogenesis and gluc

204 To determine the temporal effects of PCN treatment on the expression of Oatp2, rats were admi

205 e sequentially installed into the lattice of PCN-700.

206 rried out for the catenation isomer pairs of PCN-6 and PCN-6' (both have the formula of Cu(3)(TATB)(2

207 Here, we have studied the progression of PCN transcriptomes from dry cysts to hatched juveniles u

208 N2-adsorption studies of PCN-14 at 77 K reveal a Langmuir surface area of 2176 m2

209 ors were enriched by a combined treatment of PCN and LPS, and among these, 285 were found to have bin

210 Treatment of PCN induced the expression of the reporter gene in a dos

211 For instance, the dichromate uptake of PCN-134 is tuned by adjusting the BTB/TCPP ratios, which

212 For example, the excess hydrogen uptake of PCN-6 is 72 mg/g (6.7 wt %) at 77 K/50 bar or 9.3 mg/g (

213 PCNs smaller than 5 mm at baseline, 100% of PCNs at 3-year follow-up and 94.2% of PCNs at 5-year fol

214 00% of PCNs at 3-year follow-up and 94.2% of PCNs at 5-year follow-up were likely to remain stable.

215 of growth, as compared with the category of PCNs smaller than 5 mm.

216 We determined concentrations of PCNs in eggs of thick-billed murres (Uria lomvia) collec

217 reatment stimulated the neurite outgrowth of PCNs after OGD, which was attenuated by LY294002 and enh

218 Since a small percentage of PCNs possess malignant potential, management is challeng

219 increased with age, but due to the rarity of PCNs in younger people in the general population, SIRs w

220 sanitary program has prevented the spread of PCNs to other potato-growing areas in both countries.

221 first published study of temporal trends of PCNs in Canadian Arctic biota.

222 ared with the bare PCN and HP, the optimized PCN@HP hybrid exhibited a significantly enhanced photoca

223 eptor) and PXR in mice injected with D(3) or PCN.

224 fferent lengths were installed into a parent PCN-700, giving rise to 11 new MOFs and each bearing up

225 e Sprague-Dawley rats were injected with PB, PCN, 3-methylcholanthrene (3-MC), or vehicle for 4 days.

226 wo photochromic metal-organic frameworks, PC-PCN and SO-PCN, have been developed.

227 eaction has been successfully realized in PC-PCN while maintaining its single crystallinity.

228 ns of total suspended particles, PAHs, PCBs, PCNs, and PBDEs, were typically observed in the flaming

229 eneral population has a reported penicillin (PCN) allergy.

230 in the 10% of patients reporting penicillin (PCN) allergy, but most of these patients are not truly a

231 on two representative examples, [CuCl(phen)(PCN)].DMF (5.DMF) and [CuBr(dpq)(PCN)].2DMF (10.2DMF).

232 ey (DMW), skimmed milk (SMP), phosphocasein (PCN) and infant milk formula (IMF) powders were determin

233 Posterior PCNs showed higher sensitivity to relative input times t

234 tic (PPa, PPp, and PM), pretectal (PPd, PPv, PCN, PSp, and PSm), ventral (= pre-) thalamic (I, VM, an

235 parietal lobule (IPL), bilateral precuneus (PCN), bilateral premotor cortex, and left inferior front

236 cipants, which were accompanied by prolonged PCN and lateralized readiness potentials synchronized to

237 entrations of dexamethasone actively promote PCN and TCDD induction of UGT1A1 in Tg-UGT1 primary hepa

238 these, the redox active exotoxin pyocyanin (PCN) is produced in concentrations up to 100 mumol/L dur

239 ts of the redox-active phenazine, pyocyanin (PCN), during cystic fibrosis lung infection.

240 However, no data are available regarding PCN growth rate under the ACR-defined size categories.

241 The successful research and regulatory PCN programs in both countries rely on a network of stat

242 Remarkably, PCN-224(Co) exhibits high catalytic activity for the CO2

243 Patients with MSSA bacteremia and a reported PCN allergy should have the allergy addressed for optima

244 r patients with MSSA bacteremia and reported PCN allergy.

245 Results: PCN treatment resulted in an increased clearance of radi

246 Results: PCN treatment resulted in an increased clearance of radi

247 n via its functional connection to the right PCN.

248 On average, Sigma67TEQ-PCN in the murre eggs accounted for only 1.9% of the tot

249 accounted for the majority of the Sigma67TEQ-PCN, concentrations of which also decreased significantl

250 Similarly, PCN treatment of animals on high-fat diet increases expr

251 h concentration of mesoporous cages as SMTs, PCN-333(Al) encapsulates three enzymes with record-high

252 Additionally, SO-PCN shows catalytic activity towards photooxidation of 1

253 omic metal-organic frameworks, PC-PCN and SO-PCN, have been developed.

254 photochromic switch and photosensitizer, SO-PCN has demonstrated reversible control of (1)O2 generat

255 pore size and excellent chemical stability, PCN-333 may be of interest not only for enzyme encapsula

256 min D(3) and the catatoxic synthetic steroid PCN (pregnenolone-16alpha-carbonitrile).

257 controlled synthetic process, we synthesized PCN-223, a new porphyrinic Zr-MOF constructed from the n

258 As such, the TEQ-PCN concentrations calculated for the murre eggs in this

259 ults are consistent with the conclusion that PCN-activated PXR represses FoxA2-mediated transcription

260 In this study, we demonstrate that PCN is critical for chronic infection in mouse airways a

261 act models of infection, we demonstrate that PCN mediates tissue damage and necrosis during lung infe

262 In summary, this study establishes that PCN is an important P. aeruginosa virulence factor capab

263 etabolism and energy homeostasis reveal that PCN treatment on high-fat diet-fed mice reduces expressi

264 X-ray single crystal analysis revealed that PCN-14 consists of nanoscopic cages suitable for gas sto

265 metabolism in white adipose tissue show that PCN treatment reduces expression of Ppargamma2, Acc1, Cd

266 rption studies at 290 K and 35 bar show that PCN-14 exhibits an absolute methane-adsorption capacity

267 Moreover, ChIP assays showed that PCN treatment attenuated the binding of FoxA2 to these p

268 The PCN approach proved successful in both reconstructing th

269 The PCN-224 series not only exhibits the highest BET surface

270 We anticipate the PCN-333 with functional anchor can serve as a stable pla

271 are available, and most of them average the PCN of total populations disregarding heterogeneous dist

272 dominantly CN-52/60 and CN-42) dominated the PCN profile, the hexa-CNs (mainly CN-66/67) accounted fo

273 empts to interpret the exchange event in the PCN-333.

274 ncreased and decreased, respectively, in the PCN-treated Pxr(+/+) mice.

275 in lipogenesis) mRNA was up-regulated in the PCN-treated Pxr(+/+) mice.

276 Moreover, the PCN timing was positively correlated with ADHD symptom r

277 confirm that the catalytic activities of the PCN-700 series can be switched on and off upon reversibl

278 The breathing amplitudes of the PCN-700 series were modulated through pre-functionalizat

279 Among them, PCN-250(Fe2Co) exhibits high volumetric uptake of hydrog

280 These PCNs possess pH-responsive characteristics that can be u

281 an intermediate, which rapidly converted to PCN-223 upon milling.

282 Wild-type FVBN mice chronically exposed to PCN developed goblet cell hyperplasia and metaplasia, ai

283 analyses indicated that chronic exposure to PCN profoundly increased the lung population of recruite

284 Furthermore, after 12 weeks of exposure to PCN, mouse lungs down-regulated the expression of T help

285 dulates the activation of PXR in response to PCN treatment.

286 ed StCLV2 expression are less susceptible to PCN infection, indicating that interference of the CLV2-

287 eal ceftazidime, 46 (86.8%) had allergies to PCNs alone, 5 (9.4%) had a cephalosporin allergy alone,

288 Following liver transplantation, PCN risk was higher in recipients with cholestatic liver

289 roprotection in blood- or hemoglobin-treated PCNs and partially restores normal neuronal morphology.

290 ce of a family of isomorphic MOFs based upon PCN-14.

291 Utilizing PCN-426-Mg as a template, two robust metal-organic frame

292 PXR was retained in the cytoplasm from where PCN treatment translocated PXR into the nucleus.

293 e in product distribution was observed where PCN-222 remained the major crystal phase after 7 days, w

294 a elucidate the molecular mechanism by which PCN treatment induces rat oatp2 gene expression.

295 rs of rats treated with PB and PCN, in which PCN caused a robust elevation of Oatp2 mRNA and protein.

296 5 and PCN-224 are the kinetic products while PCN-222 is the thermodynamic product.

297 ntly upregulated (by at least 1.5-fold) with PCN treatment, and that 834 genes were significantly dow

298 Dosing rats with PCN and dexamethasone increased p-glycoprotein expressio

299 significantly increased in rats treated with PCN for 2 days but significantly decreased in 19-day pre

300 At the functional level, treatment with PCN in wild-type mice, but not PXR(-/-) mice, led to a d