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1 ng noncoding RNAs and processed into piRNAs (PIWI interacting RNAs).
2 A (miRNA), short-interfering RNA (siRNA) and Piwi-interacting RNA.
3 lls, PIWIL4 binds to a small number of known piwi-interacting RNA.
4 enomenon to paramutation that is mediated by piwi-interacting RNAs.
5 obile genetic elements, acting together with Piwi-interacting RNAs.
6 ain germline classes of small RNAs including Piwi-interacting RNAs.
7 RNAs, transfer RNA, small nuclear RNAs, and piwi-interacting RNAs.
8 udied small interfering RNAs, microRNAs, and piwi-interacting RNAs.
9 RNA intermediates to achieve optimally sized piwi-interacting RNAs.
12 ansion seems to be related to a reduction of PIWI-interacting RNAs and C2H2 zinc-finger and Kruppel-a
13 nd micro-RNA pathways; whereas PIWIs bind to PIWI-interacting RNAs and regulate germ line development
14 including small interfering RNAs, microRNAs, PIWI-interacting RNAs and RNAs derived from structured R
17 fs that are overrepresented in comparison to Piwi-interacting RNAs and transcription start site-assoc
23 r-dependent miRNAs and the Dicer-independent Piwi-interacting RNAs, associate with Argonaute family p
24 A second endogenous small RNA class, the Piwi-interacting RNAs, bind Piwi proteins and suppress t
25 , these results define PNLDC1 as a mammalian piwi-interacting RNA biogenesis factor that protects the
26 ce, here we show that PNLDC1 is required for piwi-interacting RNA biogenesis, transposon silencing, a
27 have shown that proteins involved in piRNA (PIWI-interacting RNA) biogenesis are necessary for retro
28 ld), known epigenetic regulators (2.3-fold), piwi-interacting RNA clusters (3.6-fold) and curated tra
29 ain the molecular mechanisms underlying PIWI-PIWI-interacting RNA complex function in target RNA clea
32 21-22Us show striking resemblance to the 21U PIWI-interacting RNAs found in C. elegans, including an
33 ll as a large population of putative piRNAs (piwi-interacting RNAs) had dynamic accumulation profiles
34 also highlight the recent discovery of viral PIWI-interacting RNAs in animals and a new role for mobi
35 d small interfering RNAs (siRNAs) in plants, Piwi-interacting RNAs in animals and siRNAs in Drosophil
39 ng RNAs requires a critical step of trimming piwi-interacting RNA intermediates to achieve optimally
40 rimming and causes accumulation of untrimmed piwi-interacting RNA intermediates with 3' end extension
41 previously that Piwi plays a crucial role in Piwi-interacting RNA-mediated epigenetic regulation and
43 uted to the nuage proteins, which engage the Piwi-interacting RNA pathway and other posttranscription
45 Piwil2, which encodes a key component in the Piwi-interacting RNA pathway that protects against TEs.
48 "cancer/testis antigens" (CTAs), and piRNA (PIWI-interacting RNA) pathway proteins are found among C
50 are sterile, and phenocopy mutations in the PIWI interacting RNA (piRNA) pathway, which silences tra
52 A methylation, repressive histone marks, and PIWI-interacting RNA (piRNA) are essential for the contr
53 The Piwi protein subfamily is essential for Piwi-interacting RNA (piRNA) biogenesis, transposon sile
56 insertions within specialized regions called PIWI-interacting RNA (piRNA) clusters produce small RNAs
60 nsposon insertions negatively correlate with Piwi-interacting RNA (piRNA) levels for most transposon
62 mutant animals, we probed the roles of known Piwi-interacting RNA (piRNA) pathway components in the i
63 s controlling the expression of the germline PIWI-interacting RNA (piRNA) pathway components within t
69 e essential for transposon silencing via the PIWI-interacting RNA (piRNA) pathway in the Drosophila o
70 spite exciting progress in understanding the Piwi-interacting RNA (piRNA) pathway in the germ line, l
81 , to participate in the previously described PIWI-interacting RNA (piRNA) pathway that promotes trans
82 re, the gonads of African cichlids express a Piwi-interacting RNA (piRNA) pathway that targets TEs.
83 facets-1)(Kr(If-1)) allele, we show that the Piwi-interacting RNA (piRNA) pathway, but not the short
84 in Rhino, a crucial factor of the Drosophila PIWI-interacting RNA (piRNA) pathway, is largely defined
86 ermline-specific RNAi mechanism known as the Piwi-interacting RNA (piRNA) pathway, which specifically
90 (HP1) variant Rhino permits transcription of PIWI-interacting RNA (piRNA) precursors within transposo
92 uman extracellular RNAs including microRNAs, piwi-interacting RNA (piRNA), and small nucleolar RNAs.
93 erfering RNA (siRNA), micro-RNA (miRNA), and piwi-interacting RNA (piRNA), play important roles in ma
94 enes, accompanied by increased expression of Piwi-interacting RNA (piRNA)-based TE-silencing pathway
95 f proteins containing tudor domains with the piwi-interacting RNA (piRNA)-binding Piwi proteins, and
96 binds the histone ubiquitin ligase RNF8 in a Piwi-interacting RNA (piRNA)-independent manner, and MIW
98 NAs map within annotated genes, but some are PIWI-interacting RNA (piRNA)-like and map to piRNA clust
99 singly, zuc/MitoPLD activity is required for Piwi-interacting RNA (piRNA)-mediated silencing of trans
100 PIWI-directed gene silencing, we employed a Piwi-interacting RNA (piRNA)-targeted reporter assay in
102 on a 180-kb heterochromatic locus producing Piwi-interacting RNAs (piRNA cluster), the flamenco (fla
108 Here we show that short synthetic guide Piwi-interacting RNAs (piRNAs) (21-nucleotide sg-piRNAs)
110 lencing effectors for approximately 26-32 nt Piwi-interacting RNAs (piRNAs) [1], and piwi mutants exh
113 include small interfering RNAs (siRNAs) and PIWI-interacting RNAs (piRNAs) and are implicated in nuc
114 ermore, we showed that tsRNAs are similar to Piwi-interacting RNAs (piRNAs) and demonstrated that ts-
116 In Drosophila, Piwi proteins associate with Piwi-interacting RNAs (piRNAs) and protect the germline
119 ic granule in male germ cells also harboring PIWI-interacting RNAs (piRNAs) and the piRNA-binding pro
121 ures our current understandings of mammalian PIWI-interacting RNAs (piRNAs) and their role in TE regu
148 Short deletions over sites with homology to PIWI-interacting RNAs (piRNAs) are sufficient to comprom
156 rm cells of placental mammals, 26-30-nt-long PIWI-interacting RNAs (piRNAs) emerge when spermatocytes
160 interfering RNAs (siRNAs) as well as animal piwi-interacting RNAs (piRNAs) from degradation and 3' t
165 The conserved Piwi family of proteins and piwi-interacting RNAs (piRNAs) have a central role in ge
166 ince their discovery less than a decade ago, Piwi-interacting RNAs (piRNAs) have been shown to repres
170 iRNAs), small interfering RNAs (siRNAs), and piwi-interacting RNAs (piRNAs) impact numerous biologica
171 We also report detection of virus-derived PIWI-interacting RNAs (piRNAs) in Drosophila melanogaste
172 dentification and characterization of 12,903 Piwi-interacting RNAs (piRNAs) in Drosophila, showing th
173 ssion of retrotranspons with the presence of piwi-interacting RNAs (piRNAs) in fetal male germ cells
174 p to low-copy, intergenic regions similar to PIWI-interacting RNAs (piRNAs) in mammalian testis.
176 oding RNAs (sncRNAs), microRNAs (miRNAs) and PIWI-interacting RNAs (piRNAs) in particular, define sev
177 function as templates for the biogenesis of PIWI-interacting RNAs (piRNAs) in some mosquito species
178 The PIWI protein MIWI2 and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation
179 WI protein MIWI2 (PIWIL4) and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation
180 akura is also necessary for normal levels of piwi-interacting RNAs (piRNAs) levels and for female-spe
188 n is limited by a class of small RNAs called PIWI-interacting RNAs (piRNAs) produced by dedicated gen
189 E) activity is repressed in animal gonads by PIWI-interacting RNAs (piRNAs) produced by piRNA cluster
191 germlines, PIWI proteins and the associated PIWI-interacting RNAs (piRNAs) protect genome integrity
194 azoan germline, piwi proteins and associated piwi-interacting RNAs (piRNAs) provide a defense system
206 ical for fertility, germline morphology, and Piwi-interacting RNAs (piRNAs) silencing, they are not r
207 mall interfering RNAs) and Piwi proteins and Piwi-interacting RNAs (piRNAs) suggest novel functions f
208 ughters show a markedly different content of Piwi-interacting RNAs (piRNAs) targeting each element, d
209 RNAs) and siRNAs, whereas the latter targets piwi-interacting RNAs (piRNAs) that are 2'-O-methylated
210 vered a class of noncoding small RNAs called PIWI-interacting RNAs (piRNAs) that are abundantly expre
211 n Piwi proteins, MIWI and MILI, partner with Piwi-interacting RNAs (piRNAs) that are depleted of repe
213 ound approximately 23- to 30-nucleotide (nt) PIWI-interacting RNAs (piRNAs) that are processed from s
214 amily proteins, carry approximately 24-30-nt Piwi-interacting RNAs (piRNAs) that mediate gonadal defe
216 s of Argonaute proteins-use 21-35 nucleotide PIWI-interacting RNAs (piRNAs) to direct transposon sile
218 ternative strategy employs small RNA guides, Piwi-interacting RNAs (piRNAs) to identify targets of tr
220 RNAs), tRNA-associated fragments (tRFs), and piwi-interacting RNAs (piRNAs) was measured in serum fro
222 y 29 to 30 nucleotides in length, are called Piwi-interacting RNAs (piRNAs), 94% of which map to 100
225 Piwi Argonaute protein PRG-1 and associated Piwi-interacting RNAs (piRNAs), as well as by proteins t
228 ous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), drive the repression of
229 (lncRNAs), U small nuclear RNAs (U snRNAs), PIWI-interacting RNAs (piRNAs), enhancer RNAs and nascen
230 ous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), have been shown to play
232 on the role of small RNAs, and in particular piwi-interacting RNAs (piRNAs), in the epigenetic regula
234 ous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), play essential roles in
235 (ncRNAs), especially microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs), play key roles in many b
236 iRNAs, other bilaterian small RNAs, known as Piwi-interacting RNAs (piRNAs), protect the genome from
238 UTE/PIWI protein family member that binds to Piwi-interacting RNAs (piRNAs), strongly and specificall
240 x that is normally involved in biogenesis of Piwi-interacting RNAs (piRNAs), the largest class of ger
241 n the organ- and organ system-specificity of piwi-interacting RNAs (piRNAs), transfer RNAs (tRNAs), m
243 TEs) in flies and vertebrates is mediated by Piwi-interacting RNAs (piRNAs), which are approximately
245 transcripts are processed into sense-strand PIWI-interacting RNAs (piRNAs), which may provide an ini
246 e numerous long noncoding RNAs (lncRNAs) and Piwi-interacting RNAs (piRNAs), yet the functions of the
258 nd silencing recently exemplified by piRNAs (piwi-interacting RNAs), position effect variegation, X-c
264 the binding channel and repositioning of the PIWI-interacting RNA-target duplex towards the MID-PIWI
265 the mechanism of biogenesis for tRNA-derived Piwi-interacting RNAs (td-piRNAs) expressed in Bombyx Bm
266 ng, from small interfering RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canoni
269 Similarly, the production of virus-derived piwi-interacting RNAs (vpiRNAs) was not sufficient to pr
270 re matched by small regulatory RNAs, such as piwi-interacting RNAs, which play a potent role in both
271 to the deregulation of 34 microRNAs and 668 piwi-interacting RNAs, with changes persisting unexposed