ライフサイエンスコーパス: R

1 R language has been used for the statistical analysis of

2 R loops arising during transcription induce genomic inst

3 (R)-roscovitine and M3 significantly increased killing of

4 R-(-)apomorphine and raloxifene have been shown to impro

5 R-loops are common in the genomes of pro- and eukaryotes

6 0.006, R(2)=0.38, 12.5% resolution, P=0.004, R(2)=0.41) with a phase analysis derived measure of diso

7 lower resolutions (50% resolution: P=0.006, R(2)=0.38, 12.5% resolution, P=0.004, R(2)=0.41) with a

8 e and gas recruitment (R = 0.266, p = 0.008, R = 0.357, p = 0.002, respectively).

9 mor volume (R = 0.903, P = 0.005) and MCT 1 (R = 0.85, P = 0.032) and HIF1alpha expression (R = 0.83,

10 es the angiotensin II receptor type 1 (AT(1) R) axis associated with oxidative stress.

11 ked by muscarinic (M(2)R) and adenosine (A(1)R) receptor activation in the mouse sinoatrial node (SAN

12 in cells coexpressing D(1)-receptor and A(1)R-G279S(7.44) than in those coexpressing wild-type A(1)R

13 turation: the thermodynamic stability of A(1)R-G279S(7.44) was enhanced by about 2 and 8 K when compa

14 ompared with wild-type A(1)-receptor and A(1)R-Y288A(7.53) (a folding-deficient variant used as a ref

15 44) than in those coexpressing wild-type A(1)R.

16 regulated by the endocannabinoid (eCB)/CB(1)R system.

17 r-activation of dopamine D(1) receptors (D(1)R), producing an imbalance in dopaminergic neurotransmis

18 e organotypic brain slices we found that D(1)R-induced cell death signaling and neuronal degeneration

19 receptors like the human Y(1) receptor (hY(1)R) are promising targets in cancer therapy due to their

20 ber of carboranes was introduced to the hY(1)R-preferring ligand [F(7),P(34)]-NPY by solid phase pept

21 ombining FND cauterization with VEGF TrapR(1)R(2) treatment prevented the undesired effect of the FND

22 erformance for CO(2) electroreduction (CO(2) R) to CO; this activity has often been attributed to the

23 CB(2) -R activation also decreased serum tumor necrosis factor-

24 CB(2) -R activation markedly improved hepatic inflammation, imp

25 In particular, the characteristics of AT(2)R and tools to modulate its functions will be discussed.

26 te a primary renal proximal tubule cell AT(2)R natriuretic defect in SHR that may contribute to the d

27 The direct coupled, vapor-fed CO(2)R cell yields a total Faradaic efficiency of up to 95% f

28 ty for electrochemical CO(2) reduction (CO(2)R) to CO.

29 tially deleterious signaling through CysLT(2)R, and it may contribute to the therapeutic properties o

30 ally antagonizes LTC(4) signaling at CysLT(2)R.

31 The degree of A(2A)R-D(2)R heteromer formation in schizophrenia might constitute

32 was implemented to detect native A(2A)R-D(2)R heteromers in mouse and human brain.

33 l-type-specific ablation of GSK-3beta in D(2)R+ neurons (D(2)R-GSK-3beta(-/-)) in the brain affects s

34 RGS6 and RGS9 are key regulators of D(2)R-Galpha (i/o) signaling in SNc DA neurons and striatal

35 ablation of GSK-3beta in D(2)R+ neurons (D(2)R-GSK-3beta(-/-)) in the brain affects synaptic function

36 rophore with negative charge showed high M(2)R affinities (pK(i) (radioligand competition binding): 9

37 examined signaling evoked by muscarinic (M(2)R) and adenosine (A(1)R) receptor activation in the mous

38 bated by extracellular ATP, subsequent P2Y(2)R activation, and downstream intracellular calcium-depen

39 2) unit in the same crystal, [K(crypt)](2){[(R(2)N)(3)Gd](2)[mu-eta(x):eta(x)-N(2)]} (x = 1 and 2), 5

40 The degree of A(2A)R-D(2)R heteromer formation in schizophrenia might const

41 method was implemented to detect native A(2A)R-D(2)R heteromers in mouse and human brain.

42 serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) allosteric site to potentiate endogenous 5-HT tone ma

43 uronal degeneration, are mitigated by an H(3)R antagonist.

44 ation of beta-cells were blocked by a 5-HT(3)R antagonist and were enhanced by increasing serotonin l

45 d peptide, and the serotonin receptor 5-HT(3)R.

46 [Ca(2+)](ER) is a major regulator of InsP(3)R channel activity and InsP(3)R-mediated [Ca(2+)](i) sig

47 ator of InsP(3)R channel activity and InsP(3)R-mediated [Ca(2+)](i) signaling in cells by controlling

48 Ca(2+) transient shape to properties of IP(3)R activation.

49 ss talk) between ryanodine receptor and IP(3)R channels on the Ca(2+) transient and examine the sensi

50 tency and binding affinity for Ins(1,4,5)P(3)R were similar to those of adenophostin.

51 least efficacious agonists of Ins(1,4,5)P(3)R yet identified, providing new leads for antagonist dev

52 g to Ins(1,4,5)P(3) receptors [Ins(1,4,5)P(3)R] and the ability to release Ca(2+) from intracellular

53 onuclease oligonucleotide complexes with 5'-(R)- and 5'-(S)-C-methyl substituents attached to the 5'-

54 trations (PNC; a proxy for UFP) and PM(2.5) (R(2) of 0.38 and 0.41, respectively).

55 ographical reconfiguration mediated by 5HT2A-R activation.

56 oral carcinogenesis and pain, such that ET(A)R activation and silenced ET(B)R expression result in in

57 ndings in patients, we hypothesize that ET(A)R and ET(B)R play dichotomous roles in oral carcinogenes

58 y a role in the dynamic regulation of GABA(A)R accumulation at inhibitory synapses, thereby regulatin

59 ate of the field of subtype-selective GABA(A)R modulators acting via the BZD binding site and their p

60 BZDs indicates that subtype-selective GABA(A)R modulators will have novel pharmacological profiles.

61 and silencing, we identified that the GABA(A)R subunit combination alpha3beta2gamma1 conforms the bul

62 Using GABA(A)R subunit expression and silencing, we identified that t

63 onment age on their GABA(A) receptor (GABA(A)R) responses, elicited by muscimol.

64 gle units in the auditory cortex (fields A1, R and RT) and auditory thalamus of awake, passively-list

65 , and predicted the FC (R(2) = 0.96) and AA (R(2) = 0.92) levels very well.

66 higher efficiencies in the case of absorbing R-134a at a high F-gas partial pressure.

67 , achieving highest mRNA detection accuracy (R = 0.955) and comparable sensitivity.

68 Of particular concern was the high-affinity R-state PolyhHb, which led to no improvement in hypoxic

69 After R-FC, rituximab maintenance was associated with an unexp

70 osis Functional Rating Scale-Revised (ALSFRS-R; range, 0 to 48, with higher scores indicating better

71 Altered R-Ras trafficking, increased R-Ras palmitoylation, and f

72 horseradish peroxidase conversion of Amplex(R) Red (1-(3,7-dihydroxyphenoxazin-10-yl)ethanone) to th

73 inear dynamic range of ~28 (~2-30 uM) and an R(2) value of 0.9975.

74 The software is implemented as an R package and is supported on Linux, MacOS and Windows.

75 GS functionalization screens available as an R package called malacoda (available from github.com/and

76 PRAM is implemented as an R/Bioconductor package.

77 ration response of the prototype exhibits an R(2) of 0.956.

78 (ET) from [4Fe-4S](+) to SAM, generating an R(3)S(0) radical that undergoes regioselective homolytic

79 Our method, implemented in an R package, SpectralTAD, detects hierarchical, biological

80 ermanent genetic tags for the position of an R-loop.

81 C-statistic of 0.860, c-slope of 0.997, and R(2) of 0.597.

82 showed that IQGAP1 associated with cdc42 and R-ras; this association required the GAP-related domain

83 iers can include transcription complexes and R-loops that form when RNA hybridizes with complementary

84 with each other, while both R. megaptera and R. moelleri shared only two unique traits each with wide

85 gies with large negative magnitudes of Q and R.

86 be able to stabilize both G-quadruplexes and R loops and showed a potent cell killing activity associ

87 ution, and refined the model to R (work) and R (free) values of 17.4% and 20.9%, respectively.

88 /S)-1,1'-binaphthalene]-2,2'-diol] (B) and [(R/S)-2,2'-diethoxy-1,1'-binaphthalene] (EtB) has been pe

89 ue traits each with widespread boreal-Arctic R. palpebrosa.

90 sulation of chiral guest molecules such as [(R/S)-1,1'-binaphthalene]-2,2'-diol] (B) and [(R/S)-2,2'-

91 Given our publicly available R code and data, others can complete a broad assessment

92 uch that ET(A)R activation and silenced ET(B)R expression result in increased carcinogenesis and pain

93 atients, we hypothesize that ET(A)R and ET(B)R play dichotomous roles in oral carcinogenesis and pain

94 etathesis mediated (prevalent with B-H and B-R electrophiles).

95 are (R(2) = 0.65) than in abundant bacteria (R(2) = 0.08).

96 slightly >3 d to complete and requires basic R skills.

97 and easy-to-use portable instrument (bCUBE((R)) by Hyris Ltd) that can be employed as a surveillance

98 related to summer precipitation 2 yr before (R(2) = 0.85), and negatively to precipitation in May (R(

99 The recognition between R proteins and their cognate pathogens often triggers a

100 scds is implemented as a Bioconductor R package (doi: 10.18129/B9.bioc.scds).

101 , infection, surgery, and variceal bleeding; R: systemic inflammatory response syndrome (SIRS), spont

102 High boreal R. megaptera and Arctic endemic R. moelleri shared three

103 red three traits with each other, while both R. megaptera and R. moelleri shared only two unique trai

104 n the other hand, replisomes easily bypassed R-loops on either template strand.

105 organic aerosol mass (R(2) = 0.68) and O/C (R(2) = 0.69) enhancement ratios observed across 11 chamb

106 lowed by PhMgBr ((S(c),S(p),R(phos) and S(c),R(p),S(phos), respectively).

107 newly incorporated concentration-response (C-R) functions to quantify changes in the incidence of pre

108 Results: (11)C-(R)-rolipram binding correlated with known locations of f

109 MoFe protein corresponds to a [MoFe(7)S(9)C-(R)-homocitrate] species designated FeMo-cofactor, whose

110 [(64)Cu]Cu-c[R(4)W(5)C] demonstrated significantly reduced uptake in

111 nstant coffee were determined using DR CALUX(R) bioassay, before and after intestinal metabolization

112 ox disproportionation forms [Cu(III)](C=CAr)(R) species that reductively eliminate R-C=CAr products.

113 rbapenemase genes were detected by the Carba-R assay in Klebsiella pneumoniae (n = 236), Escherichia

114 of resistance genes from colonies, the Carba-R assay reduced turnaround time from 56 to 84 h to less

115 therapies, including bicalutamide (CASODEX((R))) and enzalutamide (XTANDI((R))).

116 ke domains, mediated association with cdc42, R-ras, and IQGAP1.

117 cline in the sum of boxes score from the CDR(R) Dementia Staging Instrument and in five cognitive dom

118 Ruminococcaceae UCG-010, Christensenellaceae R-7 and plasma SCFAs in NT.

119 female ratio, 34;55) treated with Cidarcure((R)), and untreated 299 patients (age, 31.3+/-16.0; male-

120 and CT-FFR (Pearson correlation coefficient, R=0.64, P<0.0001).

121 A robust Pearson correlation (R = 0.9801 +/- 0.0167; mean +/- sd; N = 7) was determine

122 er individual and an unstructured covariance R matrix was used as correlation structure.

123 aling does not alter the film crystallinity, R-SoXS characteristic size scale, relative average phase

124 (R: 0.573; P < .01) and degradation in CSF (R: 0.611; P < .01).

125 to regulate CD8(+) T cell effector cytokine R production independent of TCR Ag affinity.

126 ropositive and recipient CMV-seronegative (D+R-) liver transplant recipients in the current era are i

127 ually decreased for more than other 40 days (R(2) = 0.545, p < 0.001).

128 The optimal regression model demonstrated R(2) values of 0.92 and 0.90 for the calibration and val

129 ighly-multi-PI-resistance-associated PR(DRV)(R)(P51) revealed that the PIs better adapt to structural

130 Early rituximab intensification during R-CHOP-14 does not improve outcome in patients with untr

131 ngth there was greater vitreous echodensity (R: 0.573; P < .01) and degradation in CSF (R: 0.611; P <

132 A flexible and efficient R package is needed for analyzing processed multilevel o

133 C=CAr)(R) species that reductively eliminate R-C=CAr products.

134 ngly with antibody levels measured by ELISA (R(2)=0.67 by Marburg VN; p<0.001).

135 High boreal R. megaptera and Arctic endemic R. moelleri shared three traits with each other, while b

136 derived from the enzalutamide-resistant (Enz-R) VCaP cell line.

137 N datasets as judged by mean absolute error, R(2) values when regressing automated vs. manual counts,

138 cess was similar between Sapien 3 and Evolut R/PRO (85.6% versus 87.2%; P=0.68).

139 his complication did not occur in the Evolut R/PRO group.

140 pien 3 and n=111 [68.6%] treated with Evolut R (n=70)/PRO [n=41]) were included.

141 = 0.85, P = 0.032) and HIF1alpha expression (R = 0.83, P = 0.043).

142 ing with a second warming event with extreme R(onset) The epizootic lasted ~2 mo, extending beyond th

143 vices on the measurements made by an eyemate(R)-IO sensor in-vitro, in an artificial and controlled e

144 P-SL70: R = 0.410, P = 0.037; App (NL-G-F) : R = 0.385, P = 0.002).

145 Net, Dilated-Net, original U-Net, and Faster R-CNN models and the conventional region growing (RG) me

146 opped iceberg lettuce, and predicted the FC (R(2) = 0.96) and AA (R(2) = 0.92) levels very well.

147 h buckthorn species and a potential gain for R. multiflora and A. petiolata.

148 rom 80 mug/ml for X. citri to 600 mug/ml for R. solanacearum and X. euvesicatoria.

149 9% per degree of measurement temperature for R(d) and V(cmax) respectively.

150 or NnOMT1 and NnOMT5 were 20 and 13 mum for (R,S)-norcoclaurine and (S)-N-methylcoclaurine, respectiv

151 MG) relaxation dispersion and rotating frame R (1rho) measurements demonstrate that MOR displays mole

152 performance (R(2)CV-0.97, RMSECV-0.38 mg/g; R(2)P-0.97, RMSEP-0.36 mg/g).

153 -child pairs participating in the Generation R Study, a population-based birth cohort in Rotterdam, N

154 glitazone increased PPARgamma binding to GIP-R PPREs.

155 ns located in the large groove of EBV gH/gL (R(152)A and G(49)C) also have decreased binding with Eph

156 Here we show a role for the Ras GTPase, R-Ras, in the functional adaptation of high endothelial

157 iastolic wall thickness-to-chamber radius (h/R) ratio increased, consistent with the development of c

158 101 patients, 41 received R-Mono and 60 had R-CHOP.

159 his application with a case study of Hecolin(R), the licensed vaccine for hepatitis E virus (HEV).

160 The human prostaglandin F receptor (hFP-R) is widely expressed in the lung tissue and constitute

161 sence of co-transcriptional RNA/DNA hybrids (R-loops) that form in infected cells during S-phase as a

162 ce develop adverse LV remodeling following I/R injury secondary to the collateral damage from sustain

163 In this Review, we highlight I/R-targeting therapeutics shown to improve microvascular

164 cocalyx is now considered a cornerstone in I/R-related endothelial dysfunction, which further impairs

165 hanging the optic material to have a lower I/R improved PD symptoms in the large majority of patients

166 High index of refraction (I/R), surface reflectivity, and IOL optic design are addit

167 trigger a version of ischemia/reperfusion (I/R) pathobiology that is singular in its origin, cyclicit

168 flow in sickle transgenic mice undergoing I/R, and we suggest how such insights might be translated

169 Icare(R) HOME allows intraocular pressure (IOP) sampling by th

170 sing the Illumina HT12 array and analysed in R using a combination of Limma and Illuminaio.

171 forms of bulk and single-cell RNAseq data in R. dittoSeq is color blindness-friendly by default, robu

172 est in GO, intermediate in PD, and lowest in R patients (P = 0.017).

173 dent layers of interactivity using Plotly in R, which aids in the exploration of large biological dat

174 Altered R-Ras trafficking, increased R-Ras palmitoylation, and fibronectin retention were fou

175 TNF induces R-Ras upregulation in endothelial cells via JNK and p38

176 testinal digestion according to the INFOGEST(R) methodology.

177 e synthase (iNOS), which we found to inhibit R. parkeri.

178 1 and the spermadhesin-1 x BSP5 interaction (R(2) = 0.84 and 0.79; p < 0.05).

179 However, although IPSS-R is an excellent predictor of disease progression, it i

180 Deletion of the entire IR-R repeat or, to a lesser degree, deletion of just the B

181 data fitting well with Freundlich isotherm (R(2) > 0.98).

182 because RLBs did not require protein kinase R, phosphorylation of eukaryotic translation initiation

183 )-40 following pseudo-second-order kinetics (R(2) > 0.97) and equilibrium isotherm data fitting well

184 synthesis of the natural product lamellarin R.

185 We developed corto, a fast and lightweight R package to infer gene networks and perform MRA from ge

186 s and maximum liver function capacity (LiMAx(R)), namely the CreLiMAx risk score.

187 The calibration showed acceptable linearity (R(2) = 0.97) and a limit of detection of 6.7 ppm.

188 ptions, the method displayed good linearity (R(2) > 0.99), with appropriate limits of detection (0.05

189 g/g), while granting satisfactory linearity (R(2) > 0.998) in a wide linear range of 0.1-2000 ng/g, r

190 n dry SS followed the Weibull model (0.96 <= R(2) <= 0.99), but the model overestimated inactivation

191 iggered ratiometric persistent luminescence (R-PersL) sensor array for the discrimination of six thio

192 In relapsed/refractory Hodgkin lymphoma (R/R HL), immunotherapies such as the anti-programmed dea

193 teractions between the globular domains of M/R and DNA, we observe transient interactions between DNA

194 the variability in the organic aerosol mass (R(2) = 0.68) and O/C (R(2) = 0.69) enhancement ratios ob

195 85), and negatively to precipitation in May (R(2) = 0.83) in the fruit years.

196 se that converts the final intermediate (MbA-R(2)) to complete the MbA molecule.

197 SF-PreCon markedly reduced MI/R injury in DM mice, as evidenced by improved cardiac fu

198 ND mice, SF-PreCon significantly reduced MI/R-induced activation of p38, a pro-death MAPK, without a

199 correlate with pancreas SUVR-1 (20-30 min) (R (2) = 0.36, P = 0.16).

200 (+) with a wide linear range of 0.1-11.5 mM (R(2) = 0.996) and high sensitivity of 106 mA M(-1) cm(-2

201 sory characteristics gave a poor to moderate R(2).

202 nucleic acids e.g. restriction-modification (R-M) or CRISPR-Cas systems.

203 se variable type I restriction-modification (R-M) system (SpnIII) has been linked to a change in caps

204 Type I restriction-modification (R-M) systems consist of a DNA endonuclease (HsdR, HsdM a

205 The S(c) configured oxazoline moiety (R = Me, i-Pr) was used to control the generation of plan

206 , the two linear ranges from 0.05 to 30 muM (R(2) = 0.9939) and 30 to 500 muM (R(2) = 0.9953) along w

207 to 30 muM (R(2) = 0.9939) and 30 to 500 muM (R(2) = 0.9953) along with LOD of 0.03 muM for Sunset Yel

208 The NanoStringTM nCounter(R) is a platform for the targeted quantification of expr

209 R = 0.667, p = 0.003) and neuroinflammation (R = 0.788, p < 0.001).

210 example, the effective reproductive number, R(e) of New Zealand's largest cluster decreased from 7 t

211 ination theory to predict the acclimation of R(d) to growth temperature via a link to V(cmax) , and c

212 suggest that m(6)A regulates accumulation of R-loops, implying a role for this modification in safegu

213 aches to map RNA-DNA hybrids, a component of R-loops, have so far not allowed quantitative comparison

214 ve iPET proceeded with 1 additional cycle of R-CHOP, whereas those with a positive iPET received invo

215 clusion waveform analysis with estimation of R(up) seems to be a valuable technique for assessing the

216 The interactions of R. parkeri with inflammasomes and interferons are simila

217 However, the mechanism of R-loop formation remains unknown.

218 terestingly, DNA flanking the RNA-5' side of R-loops is not intrinsically unstable.

219 Unexpectedly, we found that 5-OHBza-R is the most favored MtBzaC substrate.

220 were done in all patients receiving CHOP or R-CHOP.

221 racterize the R(ee) landscape by measuring P(R(ee)) for low molecular weight (MW: 0.22-2.6 kDa) dilut

222 ar nickel(II) complexes with the R(P)S(P)S(P)R(P) isomer only, in which the orientation of the lone p

223 verage brain [Li] ([Li](B) ~ 0.40 x [Li](P), R = .74).

224 f o-TolPCl(2) followed by PhMgBr ((S(c),S(p),R(phos) and S(c),R(p),S(phos), respectively).

225 and frequentist analysis via the R packages R-INLA and glmmTMB, we hope to make efficient estimation

226 sequence of a tropical rubber tree pathogen R. microporus should contribute to the better understand

227 severity and both subcortical tau pathology (R = 0.667, p = 0.003) and neuroinflammation (R = 0.788,

228 atures obtained the second best performance (R(2)CV-0.97, RMSECV-0.38 mg/g; R(2)P-0.97, RMSEP-0.36 mg

229 Persistent R-loops (RNA-DNA hybrids with a displaced single-strande

230 -LLP2A uptake, as quantified by in vivo PET (R = 0.69, P < 0.01).

231 B., & Plowright, R.

232 4 investigated Abeta mouse models (APP/PS1: R = 0.593, P = 0.001; PS2APP: R = 0.485, P = 0.019; APP-

233 dels (APP/PS1: R = 0.593, P = 0.001; PS2APP: R = 0.485, P = 0.019; APP-SL70: R = 0.410, P = 0.037; Ap

234 c shift of the optical band gap of CdSe QDs (R = 1.17 nm) of up to 111 meV while the colloidal stabil

235 basis for the emerging field of quantitative R-loop biology.

236 logeny and composition was observed in rare (R(2) = 0.65) than in abundant bacteria (R(2) = 0.08).

237 ol over the nighttime O(2) consumption rate (R(N)) in mature leaves of Arabidopsis (Arabidopsis thali

238 Among 101 patients, 41 received R-Mono and 60 had R-CHOP.

239 ted to both lung tissue and gas recruitment (R = 0.266, p = 0.008, R = 0.357, p = 0.002, respectively

240 YCs are required for full expression of red (R) light-regulated genes, including the master regulator

241 een populations, elevates long-term regional R (t) , and cumulative cases, and may even prevent disea

242 the biosensor showed a linear relationship (R(2) = 0.99) from 0.4 to 62.5 ppm of SDS with a detectio

243 human hemoglobin (PolyhHb), in the relaxed (R) or tense (T) quaternary state modulates O(2) delivery

244 ther of two arginine-rich dipeptide repeats (R-DPRs), poly(GR) and poly(PR).

245 h advanced heart failure (termed responders [R]) following left ventricular assist device (LVAD)-indu

246 Linear responses (R(2) > 0.99) were obtained, recoveries of all target ana

247 A strong correlation (Spearman's R = 0.84) was found between total VOC (C4-C12) emissions

248 APOE correlate with stroke recovery scores (R(2)=0.38-0.73, adjusted P<0.05).

249 50, +/- 0.75 and +/- 1.00 D of intended SEQ (R(2) = 0.71).

250 space in the capsid by evolving the shortest R domain.

251 001; PS2APP: R = 0.485, P = 0.019; APP-SL70: R = 0.410, P = 0.037; App (NL-G-F) : R = 0.385, P = 0.00

252 Detailed scripts in the open-source R language are freely available on GitHub, targeting use

253 U-PASS is an open-source R Shiny application.

254 s available as a web portal and a standalone R package to allow experimental and computational scient

255 (T-State) PolyhHb, relaxed quaternary state (R-State) PolyhHb, and a non O2 carrying control.

256 ts of amino acids on Pro- and Ala-stimulated R(N) were mitigated by inhibition of the Target of Rapam

257 The ABCD Study(R) has completed recruitment for the baseline sample gen

258 ageal pressure-time product (within-subjects R(2) = 0.8).

259 40) and caput-collum-diaphyseal angle (SWMR: R(2) = 0.38; T1weighted: R(2) = 0.18) compared to radiog

260 reliable assessment of Sharp's angle (SWMR: R(2) = 0.80; T1weighted: R(2) = 0.37), Tonnis angle (SWM

261 1weighted: R(2) = 0.37), Tonnis angle (SWMR: R(2) = 0.86; T1weighted: not measurable), lateral center

262 , lateral center-edge angle of Wiberg (SWMR: R(2) = 0.88; T1weighted: R(2) = 0.40) and caput-collum-d

263 immunosuppressive activity of intratumoral T(R)(eg) cells; they may also allow temporal assessment of

264 hilst much is known about the existence of T-R conflicts, our understanding of the genetic and tempor

265 Transcription-replication (T-R) conflicts are profound threats to genome integrity.

266 hyseal angle (SWMR: R(2) = 0.38; T1weighted: R(2) = 0.18) compared to radiographs with a higher accur

267 harp's angle (SWMR: R(2) = 0.80; T1weighted: R(2) = 0.37), Tonnis angle (SWMR: R(2) = 0.86; T1weighte

268 le of Wiberg (SWMR: R(2) = 0.88; T1weighted: R(2) = 0.40) and caput-collum-diaphyseal angle (SWMR: R(

269 Here we show that R-loops form at many PREs in Drosophila embryos, and cor

270 The R diastereomer is significantly more potent than the S d

271 The R script for our new utility is publicly available for d

272 The R(0) value for Brazil was estimated at 3.1 (95% Bayesian

273 In this study, we characterize the R(ee) landscape by measuring P(R(ee)) for low molecular

274 ell-type proportions and implement it in the R package medepir.

275 d that the natural levo-isomer possesses the R absolute configuration, not S.

276 ic instability, but how cells respond to the R loop-associated genomic stress is still poorly underst

277 or Bayesian and frequentist analysis via the R packages R-INLA and glmmTMB, we hope to make efficient

278 square-planar nickel(II) complexes with the R(P)S(P)S(P)R(P) isomer only, in which the orientation o

279 as elevated in the S-group compared with the R-group on all postoperative days [area under the curve:

280 validation of deconvolution results with the R/Shiny graphical user interface FactorViz.

281 e (S)-ligand in the case of quinine and the (R)-ligand in the case of quinidine, both with >99% ee.

282 ssed in intestinal crypt stem cells, bind to R-spondins (RSPOs) with high affinity, and potentiate Wn

283 aturation indicated a higher contribution to R(n).

284 ngstrom resolution, and refined the model to R (work) and R (free) values of 17.4% and 20.9%, respect

285 , while FBL55 OE plants showed resistance to R. solani challenge.

286 reventing accumulation of co-transcriptional R-loops and DNA damage to avert genomic instability and

287 ower fractional anisotropy before treatment (R = -0.5; P = .02).

288 ctions are built on top of the commonly used R packages nlme and MASS, allowing us to incorporate the

289 e in bioinformatics and statistics and using R with Bioconductor extensions.

290 S, or additional rare variants denoted as V(R).

291 cy and tolerability of VEN + BR, while VEN + R data warrant further study.

292 In viruses, R-loop investigation is limited and functional importanc

293 were obtained with 18F-flutemetamol (Vizamyl(R)) at baseline and Week 78.

294 significantly correlated with tumor volume (R = 0.903, P = 0.005) and MCT 1 (R = 0.85, P = 0.032) an

295 RAs(3) where R = Ca, Sr, thus, offers a unique opportunity to realize

296 Our results support a model in which R-DPRs interfere with cargo loading on karyopherins.

297 (7)), interacts with R-loop-enriched loci in dividing cells.

298 le safety in primarily elderly patients with R/M cSCC, supporting its use in clinical practice.

299 poor risk subtypes in patients treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincri

300 ide (CASODEX((R))) and enzalutamide (XTANDI((R))).