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1 RCM accounted for 4.5% of cases of cardiomyopathy.
2 RCM is a microscopic imaging technique, which enables th
3 RCM worked best with a W(O)(CHCMe3)(Me2Pyr)(OHMT)(PMe2Ph
4 RCM-1 is a phosphoprotein and is a substrate of PKA in v
5 ated a pixel-level segmentation model on 117 RCM mosaics collected by international collaborators.
7 to histopathological diagnosis, evaluated 3 RCM mosaic images per lesion for the presence of predefi
9 ity and increased red cell volume, but Cr-51 RCM is mandatory for patients who do not meet the define
11 shly isolated renal tubules rapidly absorbed RCM, plasma membrane integrity and cell viability remain
12 al study, a review of prospectively acquired RCM images, performed at a tertiary academic medical cen
14 (E)' electrophilic desilylation (allylsilane RCM/S(E)') to construct exo-methylidenecycloalkanes is d
15 , tolerance was assessed with an alternative RCM and BAT was carried out with the same panel used for
20 CM experience) from 6 countries evaluated an RCM study set from 100 biopsy-proven lesions, including
22 stologic data were evaluated according to an RCM morphologic classification: dendritic cell, round ce
23 barriers) for LM margin delineation using an RCM LM score previously described by our research team.
24 ducibility in recognition of tissue anchors, RCM structures that can be identified at 2 time points.
26 o etiology, prognosis, and treatment, CP and RCM share a common clinical presentation of predominantl
28 y screened in 900 patients with HCM, DCM and RCM, and disease-causing mechanisms were investigated us
31 Once a bias correction is applied, GCM- and RCM-driven US maize yields are essentially indistinguish
32 ere identified in subjects with DCM, HCM and RCM with the average cardiomyopathy prevalence of 1.66%.
38 e drugs, especially beta-lactam antibiotics, RCM and clindamycin, are common elicitors of subsequent
41 ers were shown a tissue anchor in a baseline RCM image (</= 1 x 1-mm field-of-view) and asked to iden
42 g location of this structure in the baseline RCM mosaic image (</= 5 x 5-mm field-of-view) from the s
43 macules and establish a correlation between RCM, histopathologic, and immunohistochemical findings.
45 IPr ligand shows excellent activity in both RCM and cross metathesis because of its greater stabilit
50 ls at the dermal-epidermal junction (DEJ) by RCM correlated with hyperplasia of melanocytes in hemato
52 ment was performed at defined time points by RCM, histological staining, measurement of serum alanine
53 g lymphoma and myelofibrosis-was prepared by RCM carried out at a substrate concentration 20 times gr
60 ted (DCM) and/or restrictive cardiomyopathy (RCM), but disease-causing mechanisms are not fully under
61 rditis (CP) with restrictive cardiomyopathy (RCM), or healthy controls; to assess the impact of peric
65 921), nonamyloid restrictive cardiomyopathy (RCM, n=248), or ACM (n=46) between 2005 and 2017 were in
66 ynthesis of macrocyclic alkenes by catalytic RCM; transformations deliver up to 97% of the Z isomer o
69 yne metathesis/ring-closing metathesis (CEYM/RCM) in the presence of styrene derivatives, followed by
70 hy Registry to analyze outcomes of childhood RCM, with a focus on the impact of phenotype comparing p
71 model on a separate set of 372 coregistered RCM-dermoscopic image pairs and illustrate how the resul
73 reased Ca(2+) sensitivity produced by a cTnT-RCM mutation and may account for the lack of lethality d
80 higher temperature and dilution) that drives RCM into cyclopentenes (CPs), each bearing one of the or
83 examples of catalytic enantioselective enyne RCM reactions are reported (up to 98:2 enantiomer ratio
86 ipants: Prospectively acquired and evaluated RCM images from consecutive patients with at least 1 cli
87 iate body location for confocal examination; RCM showed a high diagnostic accuracy for lesions locate
88 t in FLNC as pathogenic variant for familial RCM-a finding that further expands on the genetic basis
90 st peptide sequences, resulting in favorable RCM kinetics, helix stabilization and promotion of cellu
91 ic transposition reaction, and (4) the final RCM/dehydrogenation sequence for the formation of (-)-ac
93 presents a new translational application for RCM imaging, which, when combined with an ablative laser
96 of heart failure and therapeutic options for RCM are limited, distinction of these 2 conditions is cr
98 ree energy was also found to be positive for RCM of indole- and benzannulated terminal diolefins when
101 LV base (LE'/SE') in differentiating CP from RCM (area under the curve=0.91 versus 0.76; P=0.011).
107 nal phenotypes reminiscent of bona fide HCM, RCM, and DCM mutations; 2) a region in cTnC associated w
114 intrinsically more diagnostic information in RCM images than is currently used by individual evaluato
116 ucleus, whereas the soluble TRAIL present in RCM of H460 cells mobilized the nuclear translocation of
119 ypical features of clinical CIAKI, including RCM-induced osmotic nephrosis and increased serum levels
124 thy that the selectivity for the macrocyclic RCM can be significantly improved by tuning the catalyst
125 hich naturally infects red-capped mangabeys (RCMs), is the only SIV that uses CCR2 as its main corece
126 ing synchrotron X-ray rocking curve mapping (RCM), and were resolved into their two components of lat
127 PV owing to an elevated Cr-51 red cell mass (RCM), JAK2 positivity, and at least 1 minor criterion.
132 lizations involving ring-closing metatheses (RCM), whereas the complex featuring the IPr ligand shows
133 s followed by enyne ring-closing metathesis (RCM) and Heck cyclization afforded medicinally relevant
134 was capable of both ring closing metathesis (RCM) and ring opening metathesis polymerization (ROMP) i
135 The feasibility of ring-closing metathesis (RCM) as a synthetic entry to 10- and 11-membered dienedi
137 lid phase utilizing ring-closing metathesis (RCM) between the side chains of allylglycine (AllGly) re
138 tive alkylation and ring closing metathesis (RCM) by exploiting the four possible points of diversity
139 othly underwent the ring-closing metathesis (RCM) by using Hoveyda-Grubbs II as a catalyst to provide
140 oss-metathesis (CM)/ring-closing metathesis (RCM) cascade has been used to synthesize macrocyclic cyc
141 n a transvinylation/ring-closing metathesis (RCM) cascade reaction leading to the formation of endocy
143 ed by a Z-selective ring-closing metathesis (RCM) cyclization followed by an oxygen to carbon ring co
145 ic process known as ring-closing metathesis (RCM) has allowed access to countless biologically active
146 n A(1-11)-NH(2)) by ring closing metathesis (RCM) involving tyrosine(O-allyl) (Tyr(All)), but desally
148 nd Ru(II)-catalyzed ring-closing metathesis (RCM) led to the formation of the final 2H-pyran-2-one ri
150 rnadiene (NBD), and ring closing metathesis (RCM) reactions of diethyl diallylmalonate (DEDAM) were c
151 lexes promote enyne ring-closing metathesis (RCM) reactions, affording the corresponding endo product
152 metathesis (CM) and ring-closing metathesis (RCM) reactions, little is known with regards to their ca
154 nd approach using a ring-closing metathesis (RCM) strategy to form the C10-C11 olefinic bond failed.
155 ate tether-mediated ring-closing metathesis (RCM) study to the synthesis of Z-configured, P-stereogen
156 egy is a sequential ring-closing metathesis (RCM) that forms an unsaturated siloxane ring, followed b
159 inetic model of the ring closing metathesis (RCM), enabling a further increase in the macrocyclizatio
160 macrolide employing ring-closing metathesis (RCM), followed by selective protecting group manipulatio
164 o undergo efficient ring-closing-metathesis (RCM) reaction in the presence of the Grubbs II catalyst
165 and (ii) the ring-closing olefin metathesis (RCM) of the resulting resin-bound peptide substrates.
167 ) with PMe3, ring-closing olefin metathesis (RCM) was employed to join the aryl rings with OCH2(CH2)n
169 In vivo reflectance confocal microscopy (RCM) enables clinicians to examine lesions' morphologica
170 ort in vivo reflectance confocal microscopy (RCM) features of normal lips of different phototypes and
173 Importance: Reflectance confocal microscopy (RCM) improves diagnostic accuracy in skin cancer detecti
174 oscopy with reflectance confocal microscopy (RCM) in an attempt to determine which imaging modality f
175 e efficacy of real-time confocal microscopy (RCM) in assessing viability of steatotic livers in compa
177 -resolution reflectance confocal microscopy (RCM) may offer a means for examining margins directly on
178 haracterize reflectance confocal microscopy (RCM) morphologic patterns of melanomas in multiple prima
181 by means of reflectance confocal microscopy (RCM), ambiguous pigmented facial macules and establish a
184 d modeling in which regional climate models (RCMs) are driven with general circulation model (GCM) ou
186 d the relocalization of chromatin modifiers (RCM), we hypothesize that increased CpG density is prote
187 ing resolution at cellular-level morphology, RCM imaging combined with mosaicking has shown to be hig
189 only model can be improved via a multimodal (RCM + dermoscopy) approach, which can help quantify the
191 rquartile range, 46-62 years] for nonamyloid RCM, P<0.001) and were more commonly Interagency Registr
193 ACM relative to those with DCM or nonamyloid RCM (P<0.001) but did not differ significantly between g
194 ompared with patients with DCM or nonamyloid RCM who received durable MCS, those with ACM experienced
196 y a detailed discussion on 3 major causes of RCM, for which tailored interventions are available: car
200 peritubular capillaries within 20 minutes of RCM application in uninjured mice and similar, but less
202 ynthesis of poitediol showcases the power of RCM for constructing eight-membered rings and features a
205 al retrospective web-based study of a set of RCM images collected at a tertiary academic medical cent
208 n groups with 1-, 2-, and 5-year survival of RCM 82%, 80%, and 68% versus RCM/HCM 77%, 74%, and 68%.
211 dermatologists (6 of whom had >/=3 years of RCM experience) from 6 countries evaluated an RCM study
213 f the PKA-dependent phosphorylation sites on RCM-1 results in WC-independent transcription of frq and
214 In a total of 1279 lesions in 1147 patients, RCM sensitivity and specificity were 95.3% and 83.9%, re
217 ed with a pleitropic syndrome of progressive RCM, atrioventricular septal defects, and a high prevale
219 us on the impact of phenotype comparing pure RCM with cases that have additional features of hypertro
220 ifferent between groups, but 10% of the pure RCM group was diagnosed in infancy versus 24% of the RCM
222 itivity was higher for experienced vs recent RCM users (91.0% vs. 84.8%), but specificity was similar
225 ning metathesis-ring-closing metathesis (ROM-RCM) of a bicyclo[2.2.2]octene derivative having an appr
226 provided a decalin system in contrast to ROM-RCM of the corresponding bicyclo[2.2.1]heptene analogues
228 ning metathesis/ring-closing metathesis [ROM/RCM] cascade vs ring-closing metathesis/ring-opening met
230 ning trienes and tetraenes undergo selective RCM and cross metathesis to afford functionalized spiroh
233 y the same structure in 1 of 4 equally sized RCM images obtained from the same nevus at follow-up.
235 eactivity of these substrates under standard RCM conditions, we applied DFT calculations to reveal th
238 oscopically visible lesions had subclinical (RCM-identified) disease evident more than 5 mm beyond th
243 ols underwent a highly chemoselective tandem RCM hydrogenation reaction with retention of the enantio
244 t only showcase the utility of this tethered RCM variant but have also prompted us to suggest that th
245 a translational attempt, we demonstrate that RCM is a suitable diagnostic tool to obtain information
246 served in vitro and ex vivo, indicating that RCM do not induce apoptosis or regulated necrosis of ren
248 The results of this study suggest, that RCM mechanism is feasible with viscous material extrusio
254 uration of the double bond formed during the RCM depends upon the order of synthetic sequence used.
255 conditions were identified that enhanced the RCM product yield while suppressing desallyl products us
256 al is independent of phenotype; however, the RCM/HCM phenotype has significantly better transplant-fr
259 Efforts directed toward incorporating the RCM/S(E)' sequence into a synthesis of caryophyllene are
260 starting from R-mandelic acid, involving the RCM reaction to install the C18-C19 ring junction, was s
263 pairs and illustrate how the results of the RCM-only model can be improved via a multimodal (RCM + d
267 Surgical excision margins (based on the RCM mapping) were histopathologically involved in only 2
269 roducts thereof was demonstrated through the RCM based stereoselective synthesis of various natural p
271 yclic system could, however, be made through RCM of the elusive ROM product prepared from the same bi
272 elop melanoma can be identified according to RCM morphologic classification, with dendritic cell mela
273 These strategies should be applicable to RCM involving Tyr(All) and similar residues in peptide a
277 scopically equivocal skin lesion referred to RCM imaging, from January 2012 to October 2014, carried
278 espectively, which were further subjected to RCM to furnish compounds 61 and 64 and, after removal of
280 in individuals with phototype 1 skin types; RCM features, such as junctional thickening, dense derma
281 have been reported, and mutations underlying RCM have been identified in genes that govern the contra
282 rs were shown a tissue anchor in a follow-up RCM image (</= 1 x 1-mm field-of-view) and asked to anno
287 ngitudinal systolic strain ratios (CP versus RCM and normal; LVLWS/LVSWS: 0.8+/-0.2 versus 1.1+/-0.2
289 ed 11-membered dienediyne to be obtained via RCM; the alkyne complexation strategy therefore provides
292 owed by RCM delivers the cis isomer, whereas RCM followed by Fischer indolization gives the trans iso
295 ee-dimensional (3D) mapping is feasible with RCM to delineate the lateral border and thickness of the
296 (S37G, V44Q, and L48Q) were identified with RCM-like properties (a large increase in Ca(2+) sensitiv
300 igher in patients with CP than in those with RCM (P<0.001), and both techniques were found to have si