ライフサイエンスコーパス: RNA-dependent

1 classified as not, partially, or completely RNA dependent.

2 on of HDAC1/2 and SRSF1 to the gene body was RNA-dependent.

3 The association between PABPC1 and hEndoV is RNA dependent and furthermore, PABPC1 stimulates hEndoV

4 ranscriptionally active chromatin in both an RNA-dependent and -independent manner and that this asso

5 model of multistep FUS aggregation involving RNA-dependent and RNA-independent stages.

6 the transcription factor CTCF as completely RNA dependent, and we uncovered that RNA is required for

7 rst evidence that astroviruses undergo viral RNA-dependent assembly.

8 irment of DHX9/EWS-FLI1 interaction promoted RNA-dependent association of Sam68 with DHX9 and recruit

9 Rho utilizes its RNA-dependent ATPase activities to translocate along the

10 lex at high pH and increases Delta247-Brr2's RNA-dependent ATPase activity and the extent of RNA unwi

11 l RNA helicase activities, as exemplified by RNA-dependent ATPase activity and unwinding of the DNA-R

12 An HTS campaign using an RNA-dependent ATPase assay and initial SAR study identif

13 hese Psis interact genetically with Prp5, an RNA-dependent ATPase involved in monitoring the U2 BSRR-

14 Brr2 is an RNA-dependent ATPase required to unwind the U4/U6 snRNA

15 uited to active genes and interacts with the RNA-dependent ATPase Sub2 to facilitate the formation of

16 eIF4A is a DEAD-box RNA-dependent ATPase thought to unwind RNA secondary str

17 ptional RNA processing factors including the RNA-dependent ATPase UAP56/DDX39B and histone modifiers

18 ively charged surfaces on CD1 is involved in RNA-dependent attenuation of A3B catalysis.

19 FXR1 isoforms vary in the formation of RNA-dependent biomolecular condensates in cells and in v

20 heir stability and dynamics, suggesting that RNA-dependent capsid dynamics play an important biologic

21 teracts with eRNAs, stimulation manifests in RNA-dependent changes in the histone acetylation mediate

22 ggesting that context is a crucial factor in RNA-dependent chromatin remodeling inhibition.

23 Together our data show that DNA-PK has RNA-dependent, cNHEJ-independent functions during riboso

24 ited to chromatin via RNA and forms a large, RNA-dependent complex with Yra1 and Mex67.

25 RNA-dependent cytosine methylation is also reduced, but

26 lectively, our data provide novel insight in RNA-dependent DDR by coupling DSB-induced c-Abl activity

27 Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical ro

28 s of the large and highly abundant family of RNA-dependent DEAD-box ATPases (DDXs)(3) are regulators

29 Gle1 is a conserved modulator of RNA-dependent DEAD-box proteins required for mRNA export

30 Interestingly, RNA-dependent disruption of Gag trafficking required eit

31 RNA dependent DNA-polymerases, reverse transcriptases, a

32 017) describe how the Rad52 protein mediates RNA-dependent DNA double-strand break repair via inverse

33 viously, it was reported that mutants in the RNA-dependent DNA methylation (RdDM) pathway might be in

34 nd increases in the reproductive SAM via the RNA-dependent DNA methylation pathway.

35 n tubes of mutants defective for MET1, DDM1, RNA-dependent DNA methylation, or MSI-dependent histone

36 riEPRV, potentially providing a signature of RNA-dependent DNA methylation.

37 This is reminiscent of naturally occurring RNA-dependent DNA polymerases, including telomerase, whi

38 RNA)-guided RNase that also possesses target RNA-dependent DNase and cyclic oligoadenylate (cOA) synt

39 exact mechanism of how Rad52 contributes to RNA-dependent DSB repair remained unknown.

40 RNA interference (RNAi) is an RNA-dependent gene silencing approach controlled by an R

41 ment for Aquarius, but not HRDE-1, for small RNA-dependent gene silencing.

42 t invading foreign genetic elements by small RNA-dependent gene-silencing pathways.

43 n termination events in bacteria rely on the RNA-dependent helicase Rho.

44 ces, called the terminators, or by a nascent RNA-dependent helicase, Rho.

45 he concept that RNA modifications can impair RNA-dependent immune activation.

46 ated CRISPR-Cas variants might mediate guide RNA-dependent integration of the respective transposons.

47 eq, we investigated the functional impact of RNA-dependent interaction between JMJD6 and U2AF65, reve

48 lation-mimicking mutation K376Q impaired the RNA-dependent interaction of G3BP1 with poly(A)-binding

49 To analyze an RNA-dependent interaction with chromatin, we purified na

50 Moreover, Pum1 and Pum2 display RNA-dependent interaction with fragile X mental retardat

51 unctions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellula

52 fic SR-related proteins during splicing in a RNA dependent manner.

53 nds to pericentromeric heterochromatin in an RNA-dependent manner and that Vgl1 deletion leads to los

54 roteins interacting with multiple RBPs in an RNA-dependent manner are enriched for RBPs.

55 ion interferes with IFIT1 binding, but in an RNA-dependent manner, whereas translation assays reveal

56 action of RBFox2 with chromatin in a nascent RNA-dependent manner.

57 nRNA loci and interacts with Pol-II in a DNA/RNA-dependent manner.

58 PB2), and also with nucleoprotein (NP) in an RNA-dependent manner.

59 3' end cross-links directly to Prp43p in an RNA-dependent manner.

60 Our results suggest that this non-coding-RNA-dependent mechanism evolved to survey the microbial

61 ve function for these granules as well as an RNA-dependent mechanism for scaffolding them.

62 circuits, including multistage cascades and RNA-dependent networks that can be rewired with Csy4 to

63 ells and is retained by interaction with the RNA-dependent nuclear matrix.

64 rans depending on whether the mechanisms are RNA-dependent or -independent.

65 These data establish a new RNA-dependent paradigm for myofibroblast formation throu

66 code a proof-reading deficient, low-fidelity RNA-dependent polymerase (RdRp), which generates genetic

67 The EBOV RNA-dependent polymerase complex includes a filovirus-sp

68 The small RNA-dependent, positive regulation of RNase BN in expone

69 situation and show that the double-stranded RNA-dependent protein kinase (PKR) is involved in the lo

70 AV L(pro) interfered with phosphorylation of RNA-dependent protein kinase (PKR) or eIF2alpha, indicat

71 eIF-2alpha kinases including double-stranded RNA-dependent protein kinase (PKR), which has been recen

72 cted, which results in the activation of the RNA-dependent protein kinase (PKR)-mediated stress respo

73 n is highly regulated by the double-stranded RNA-dependent protein kinase (PKR).

74 rt that in HeLa cells, activation of a PERK (RNA-dependent protein kinase [PKR]-like ER kinase)-eIF2a

75 protein interferon-inducible double-stranded RNA-dependent protein kinase activator A), the product o

76 The role of RNA-dependent protein kinase R (PKR) and its association

77 oester-dependent peptide ligations preceding RNA-dependent protein synthesis during the evolution of

78 of the MS dataset to automatically identify RNA-dependent proteins (proteins whose interactome depen

79 d, and enrichment-free screen called R-DeeP (RNA-dependent proteins), based on density gradient ultra

80 ntitative mass spectrometry identified 1,784 RNA-dependent proteins, including 537 lacking known link

81 uencing reveals that recCas9 catalyzes guide RNA-dependent recombination in human cells with an effic

82 w that several hit compounds can prevent the RNA-dependent recruitment of the ALS-associated RNA-bind

83 tral set of peptides active as co-factors in RNA-dependent replication and catalysis.

84 l enhancers requires assembly of an enhancer RNA-dependent ribonucleoprotein (eRNP) complex exhibitin

85 The structure reveals that the RNA dependent RNA polymerase (RdRp) and capping (Cap) do

86 l PPIs including the homodimerization of the RNA dependent RNA polymerase (RdRp), the self-interactio

87 h the only protein present is the poliovirus RNA dependent RNA polymerase (RdRp), which recapitulates

88 replication, which is performed by the viral RNA dependent RNA polymerase (RdRp).

89 lly activated siRNA (easiRNA) that depend on RNA DEPENDENT RNA POLYMERASE 6 (RDR6).

90 nd comprises a methyltransferase (MTase) and RNA dependent RNA polymerase domain.

91 inhibitors of norovirus 3C-like protease and RNA dependent RNA polymerase.

92 h is transcribed and replicated by the viral-RNA-dependent RNA polymerase (FluPol(A)) composed of PB1

93 Influenza viruses encode a viral RNA-dependent RNA polymerase (FluPol), which is responsi

94 on between arenavirus nucleoprotein (NP) and RNA-dependent RNA polymerase (L protein), the two trans-

95 es are catalyzed by a complex comprising the RNA-dependent RNA polymerase (L) and the tetrameric phos

96 een the hemagglutinin-neuraminidase (HN) and RNA-dependent RNA polymerase (L) genes of the PIV5 genom

97 ion protein 35 (VP35), glycoprotein (GP) and RNA-dependent RNA polymerase (L) proteins.

98 the surface of the thumb domain of the viral RNA-dependent RNA polymerase (NS5B).

99 stributed within other regions of E, the NS5 RNA-dependent RNA polymerase (NS5POL) domain, and the TM

100 entary sequence of which codes for the viral RNA-dependent RNA polymerase (NS7).

101 nsp14 associates with the CoV RNA-dependent RNA polymerase (nsp12-RdRp), and nsp14-Exo

102 Foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp) (3D(pol)) catalyzes

103 nce the amplification of the viral siRNAs by RNA-dependent RNA polymerase (RdRP) 1 (RDR1) and RDR6 an

104 s have suggested that multiple copies of the RNA-dependent RNA polymerase (RdRp) 3D are involved in t

105 of two extensively interacting subunits: an RNA-dependent RNA polymerase (RdRP) and an NTPase VP4.

106 eEF1A) in control of activation of the viral RNA-dependent RNA polymerase (RdRp) and regulation of th

107 wo conserved amino acid substitutions in the RNA-dependent RNA polymerase (RdRp) and six in the capsi

108 substitutions in the thumb subdomain of the RNA-dependent RNA polymerase (RdRp) and the methyltransf

109 The viral RNA-dependent RNA polymerase (RdRp) causes the TSS/surro

110 The influenza virus RNA-dependent RNA polymerase (RdRP) cleaves the 5' end o

111 l interfering RNAs (endo-siRNAs) produced by RNA-dependent RNA polymerase (RdRP) complexes.

112 pped dsRNAs, the largest of which encodes an RNA-dependent RNA polymerase (RdRP) containing a unique

113 protruding into an active site cavity of the RNA-dependent RNA polymerase (RdRp) domain.

114 First, the NS5 methyltransferase and RNA-dependent RNA polymerase (RdRP) domains form a conse

115 ich the tandem methyltransferase (MTase) and RNA-dependent RNA polymerase (RdRp) domains stack into o

116 itu structures of the intermediate stages of RNA-dependent RNA polymerase (RdRp) during transcription

117 ngle-stranded RNA virus that encodes its own RNA-dependent RNA polymerase (RdRp) for nucleic acid syn

118 sid (ORF2) genes and occasionally within the RNA-dependent RNA polymerase (RdRP) gene.

119 ghlight the central role played by the viral RNA-dependent RNA polymerase (RdRp) in the recombination

120 The viral RNA-dependent RNA polymerase (RdRp) is a promising thera

121 cleotide incorporation fidelity of the viral RNA-dependent RNA polymerase (RdRp) is important for mai

122 The RNA-dependent RNA polymerase (RdRp) of hepatitis C virus

123 port an in vitro RNA synthesis assay for the RNA-dependent RNA polymerase (RdRP) of rabies virus (RAB

124 RDV targets the viral RNA-dependent RNA polymerase (RdRp) of severe acute resp

125 The reliance of the viral RNA-dependent RNA polymerase (RdRP) on host factors make

126 at transgenic mice expressing a picornavirus RNA-dependent RNA polymerase (RdRP) outside the viral co

127 alone and I212V-S460L in combination) in the RNA-dependent RNA polymerase (RdRp) region of the genome

128 a distinct class of siRNAs synthesized by an RNA-dependent RNA polymerase (RdRP) requires the PIR-1 p

129 The viral RNA-dependent RNA polymerase (RdRP) resides within an ap

130 The hantavirus RNA-dependent RNA polymerase (RdRp) snatches 5' capped m

131 ny eukaryotic organisms encode more than one RNA-dependent RNA polymerase (RdRP) that probably emerge

132 RNA viruses replicate via a virally encoded RNA-dependent RNA polymerase (RdRP) that uses a unique p

133 loped, double-strand RNA viruses, package an RNA-dependent RNA polymerase (RdRp) with each duplex of

134 Dengue virus (DENV) NS5 RNA-dependent RNA polymerase (RdRp), an important drug t

135 re dengue genome for interactions with viral RNA-dependent RNA polymerase (RdRp), and we identified t

136 th simple genomes that typically encode only RNA-dependent RNA polymerase (RdRP), capping enzyme and

137 influenza virus genome mainly depend on its RNA-dependent RNA polymerase (RdRP), composed of the PA,

138 rotein template and the L protein, which has RNA-dependent RNA polymerase (RdRp), GDP polyribonucleot

139 ing well-defined mutations in the poliovirus RNA-dependent RNA polymerase (RDRP), namely, a G64S muta

140 which encode a putative coat protein and an RNA-dependent RNA polymerase (RdRp), respectively.

141 The VRC consists of the p92 virus-coded RNA-dependent RNA polymerase (RdRp), the viral p33 RNA c

142 dsRNA1 ORF contains motifs representative of RNA-dependent RNA polymerase (RdRp), whereas the dsRNA2

143 synthesis is catalyzed by a multifunctional RNA-dependent RNA polymerase (RdRP), which is composed o

144 etween mitochondrial membranes and the viral RNA-dependent RNA polymerase (RdRp), which is mediated b

145 The virus-coded RNA-dependent RNA polymerase (RdRp), which is responsibl

146 plication of SARS-CoV-2 depends on the viral RNA-dependent RNA polymerase (RdRp), which is the likely

147 nically express low levels of a picornaviral RNA-dependent RNA polymerase (RdRP), which synthesizes d

148 e of ~3 kb, encoding only a highly conserved RNA-dependent RNA polymerase (RdRp).

149 incorporated into RNA by the virally encoded RNA-dependent RNA polymerase (RdRp).

150 They all make their own RNA-dependent RNA polymerase (RdRp).

151 hich are known as inhibitors of the HCV NS5B RNA-dependent RNA polymerase (RdRp).

152 on the regulation of VP1, the virus-encoded RNA-dependent RNA polymerase (RdRp).

153 (siRNAs) are amplified from target mRNAs by RNA-dependent RNA polymerase (RdRP).

154 via template switching by the virus-encoded RNA-dependent RNA polymerase (RdRP).

155 and replication of the viral genome by viral RNA-dependent RNA polymerase (RdRp).

156 s is transcribed and replicated by the viral RNA-dependent RNA polymerase (RdRP).

157 sites in the L gene-which encodes the viral RNA-dependent RNA polymerase (RdRp).

158 d by endogenous RNA transcription through an RNA-dependent RNA polymerase (RdRp).

159 me of influenza viruses is replicated by the RNA-dependent RNA polymerase (RNAP) via a complementary

160 NA) genome, which is replicated by the viral RNA-dependent RNA polymerase (RNAP).

161 re that is recognized and bound by the viral RNA-dependent RNA polymerase (RNAP); however, no 3D stru

162 For NSVs, the viral RNA-dependent RNA polymerase (vRdRp) must gain access to

163 The viral RNA-dependent RNA polymerase (vRdRp) of MuV consists of

164 requires nuclear RNA polymerase IV (Pol IV), RNA-dependent RNA polymerase 2 (RDR2) and DICER-like 3 (

165 24-nt siRNAs are dependent on RNA Pol IV and RNA-DEPENDENT RNA POLYMERASE 2 (RDR2) and establish DNA

166 of a physical association between JMJ24 and RNA-dependent RNA polymerase 2 (RDR2), which represents

167 d Pol IV termination-dependent activation of RNA-DEPENDENT RNA POLYMERASE 2, which partners with Pol

168 , we found that METTL3 interacted with viral RNA-dependent RNA polymerase 3D and induced enhanced sum

169 analysis of cis and trans activities of the RNA-dependent RNA polymerase 3D.

170 element mRNAs into small RNAs guided by the RNA-dependent RNA polymerase 6 (RDR6) protein and is the

171 n particular, the double-mutant of paps1 and rna-dependent rna polymerase 6 (rdr6) shows a synergisti

172 However, DCL2 facilitates the recruitment of RNA-DEPENDENT RNA POLYMERASE 6 (RDR6) to ARGONAUTE 1-der

173 entified: RNA Polymerase IV (PolIV)-RdDM and RNA-dependent RNA Polymerase 6 (RDR6)-RdDM.

174 ents are converted to double-stranded RNA by RNA-dependent RNA polymerase 6 (RDR6).

175 of NAD(+) capping are instead processed into RNA-dependent RNA polymerase 6-dependent small RNAs, res

176 in, which comprises three enzymatic domains (RNA-dependent RNA polymerase [RdRp], polyribonucleotidyl

177 st of the IPR genes in a manner dependent on RNA-dependent RNA polymerase activity and on DRH-1.

178 roles for ncRNAs, as well as a novel Pol II RNA-dependent RNA polymerase activity that regulates an

179 nse program by sensing the products of viral RNA-dependent RNA polymerase activity.

180 ction of nsp8 (plus nsp7) for nsp12-mediated RNA-dependent RNA polymerase activity.

181 elity of foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase allows FMDV to exhibit high

182 ed as a core ring-like domain containing the RNA-dependent RNA polymerase and an appendage of globula

183 ce gene was identified, shown to code for an RNA-dependent RNA polymerase and to be allelic with Ty-3

184 hod allows accurate fitting of the monomeric RNA-dependent RNA polymerase bound at the threefold axis

185 pecifically impairs the function of the hRSV RNA-dependent RNA polymerase complex notably by reducing

186 lymerase basic 2 (PB2) proteins comprise the RNA-dependent RNA polymerase complex responsible for vir

187 of the genome are rendered accessible to the RNA-dependent RNA polymerase complex, possibly enabling

188 omponents: a helical ribonucleocapsid and an RNA-dependent RNA polymerase composed of a catalytic sub

189 Influenza virus RNA-dependent RNA polymerase consists of three viral pro

190 P-OD associates with the RNA-dependent RNA polymerase domain of L and protrudes a

191 ociated N protein in the architecture of the RNA-dependent RNA polymerase domain of L.

192 viruses replicate by using a virally encoded RNA-dependent RNA polymerase enzyme that has low fidelit

193 protease/helicase and NS5 methyltransferase/RNA-dependent RNA polymerase form part of the viral repl

194 The RNA-dependent RNA polymerase from the Hepatitis C Virus

195 ular screening and partial sequencing of the RNA-dependent RNA polymerase gene.

196 genome is replicated and transcribed by the RNA-dependent RNA polymerase holoenzyme (subunits nsp7/n

197 ability and poor activity of the avian virus RNA-dependent RNA polymerase in human cells.

198 a A virus mRNAs are transcribed by the viral RNA-dependent RNA polymerase in the cell nucleus before

199 bonucleosides form a novel class of HCV NS5B RNA-dependent RNA polymerase inhibitors, displaying EC50

200 Influenza virus mRNA synthesis by the RNA-dependent RNA polymerase involves binding and cleava

201 his context, heterotrimeric viral PA/PB1/PB2 RNA-dependent RNA polymerase is an attractive target for

202 on of the endonuclease activity of influenza RNA-dependent RNA polymerase is attractive for the devel

203 d the subsequent Pro(323)Leu mutation in the RNA-dependent RNA polymerase led to the precipitous spre

204 MuV RNA-dependent RNA polymerase minimally consists of the p

205 ocoris ostravirus 1) with a highly divergent RNA-dependent RNA polymerase missed by conventional BLAS

206 Our data uncover a new role for the viral RNA-dependent RNA polymerase NS5B and p7 proteins in con

207 our results demonstrate a novel role for the RNA-dependent RNA polymerase NS5B in HCV assembly.

208 The hepatitis C virus RNA-dependent RNA polymerase NS5B is responsible for the

209 replication complex consisting of NS5A, the RNA-dependent RNA polymerase NS5B, and c-Src.

210 The RNA-dependent RNA polymerase of influenza virus consists

211 remature termination of RNA synthesis by the RNA-dependent RNA polymerase of some viruses.

212 cles and if it showed positive results on an RNA-dependent RNA polymerase or open reading frame 1b ge

213 ost attention is focused on either the viral RNA-dependent RNA polymerase or the main viral protease,

214 One attractive target is the RNA-dependent RNA polymerase PA subunit.

215 mals may have replaced an ancient eukaryotic RNA-dependent RNA polymerase pathway to control transpos

216 The results show that the RNA-dependent RNA polymerase plays a crucial role in rec

217 products corresponding to virion-associated RNA-dependent RNA polymerase protein (RdRp), glycoprotei

218 with enzymatic activity, the viral large (L) RNA-dependent RNA polymerase protein.

219 ring, channels transcripts to the associated RNA-dependent RNA polymerase RDR2.

220 findings further our understanding of viral RNA-dependent RNA polymerase structure-function relation

221 Non-structural protein 5B (NS5B) is the RNA-dependent RNA polymerase that catalyzes replication

222 NS5B is the RNA-dependent RNA polymerase that catalyzes the replicat

223 Nonstructural protein 9 (Nsp9) is the RNA-dependent RNA polymerase that plays a critical role

224 RSV has an RNA-dependent RNA polymerase that transcribes and replic

225 ties of Phlebovirus nucleocapsid protein and RNA-dependent RNA polymerase to recognize the untranslat

226 tered inside the nucleocapsid when the viral RNA-dependent RNA polymerase uses it as the template for

227 agment screen on the dengue virus serotype 3 RNA-dependent RNA polymerase using x-ray crystallography

228 P forms the viral RNA-dependent RNA polymerase with the large protein (L).

229 oronavirus 2, also known as 2019-nCoV) RdRp (RNA-dependent RNA polymerase) coding sequence, achieving

230 g of heterotypic segments by influenza virus RNA-dependent RNA polymerase, an inhibitory effect of vi

231 onsisting of genomic RNA, nucleoprotein, the RNA-dependent RNA polymerase, and a polymerase cofactor,

232 ns-acting short interfering RNA3 pathway, an RNA-dependent RNA polymerase, and an XH/XP domain-contai

233 ease (3CLpro), papain-like protease (PLpro), RNA-dependent RNA polymerase, and spike (S) protein.

234 s is transcribed and replicated by the viral RNA-dependent RNA polymerase, composed of the subunits P

235 f viral RNA synthesis by the recombinant MNV RNA-dependent RNA polymerase, confirming that the stem-l

236 logical salt conditions, HCV NS5BDelta21, an RNA-dependent RNA polymerase, has poor affinity for the

237 1 (PA-PB1) subunits of influenza virus (Flu) RNA-dependent RNA polymerase, this paper is devoted to t

238 s, identified in the p7 polypeptide and NS5B RNA-dependent RNA polymerase, were sufficient to increas

239 lyzed by the NS5B (nonstructural protein 5B) RNA-dependent RNA polymerase, which is a major target of

240 The virus encodes an RNA-dependent RNA polymerase, which replicates and trans

241 ical, concerted action of RNA POLYMERASE IV, RNA-DEPENDENT RNA POLYMERASE-2, and DICER-LIKE-4.

242 single open reading frame (ORF) encoding an RNA-dependent RNA polymerase.

243 RNA genomes of 2.2 to 4.4 kb, encoding only RNA-dependent RNA polymerase.

244 y an HEV variant harboring a mutation in the RNA-dependent RNA polymerase.

245 ld have arisen as a secondary function of an RNA-dependent RNA polymerase.

246 virus replication, the methyltransferase and RNA-dependent RNA polymerase.

247 etermine the recognition of viral RNA by the RNA-dependent RNA polymerase.

248 mechanistic understanding of NS5B, the viral RNA-dependent RNA polymerase.

249 al agent specifically targeting HCV NS5B, an RNA-dependent RNA polymerase.

250 levels of siRNAs through the activity of an RNA-dependent RNA polymerase.

251 osttranscriptional gene-silencing components RNA-DEPENDENT RNA POLYMERASE1 and SUPPRESSOR OF GENE SIL

252 on P. patens homologs of DICER-LIKE3 (DCL3), RNA-DEPENDENT RNA POLYMERASE2, and the largest subunit o

253 ced by the activity of ARGONAUTE9 (AGO9) and RNA-DEPENDENT RNA POLYMERASE6 (RDR6), two genes involved

254 marily a replicative process mediated by the RNA-dependent RNA polymerase; (iii) a mutation shown to

255 1 dephosphorylates ppp-RNAs made by cellular RNA-dependent RNA polymerases (RdRPs) and is required fo

256 RNA-dependent RNA polymerases (RdRps) are used by RNA vi

257 RNA-dependent RNA polymerases (RdRps) are used by RNA vi

258 Positive-sense RNA viruses encode RNA-dependent RNA polymerases (RdRps) essential for geno

259 Recombinant RNA-dependent RNA polymerases (RdRps) from the human nor

260 Picornaviral RNA-dependent RNA polymerases (RdRPs) have low replicati

261 through the production of small RNAs by two RNA-dependent RNA polymerases (RdRPs) that are thought t

262 atively low fidelity SARS-CoV and SARS-CoV-2 RNA-dependent RNA polymerases (RdRps), serving as an imm

263 ed host thanks to dedicated, virally-encoded RNA-dependent RNA polymerases (RdRps).

264 te for the absence of piRNAs, both involving RNA-dependent RNA polymerases (RdRPs).

265 RDV is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps).

266 oduction of double-stranded RNAs (dsRNAs) by RNA-DEPENDENT RNA POLYMERASEs (RDRs) and proceeds throug

267 Cellular RNA-dependent RNA polymerases (RDRs) catalyze synthesis

268 The viral RNA-dependent RNA polymerases (vRdRps) of nonsegmented,

269 ve identified fidelity determinants in viral RNA-dependent RNA polymerases and have shown that RNA vi

270 Viral RNA-dependent RNA polymerases are considered to be low-f

271 We find that in this group of viruses, RNA-dependent RNA polymerases do not direct genome order

272 The error-prone nature of RNA-dependent RNA polymerases drives the diversity of RN

273 al clamp, conferring steric hindrance on the RNA-dependent RNA polymerases of diverse positive-strand

274 sponsible for virus replication and cellular RNA-dependent RNA polymerases responsible for gene silen

275 of mutations in virus-derived siRNAs: viral RNA-dependent RNA polymerases responsible for virus repl

276 such as influenza, encode large, multidomain RNA-dependent RNA polymerases that can both transcribe a

277 lication showed the contribution of cellular RNA-dependent RNA polymerases to the generation of mutat

278 xhibit a non-spooled arrangement mediated by RNA-dependent RNA polymerases(11-14).

279 G tails promote gene silencing by recruiting RNA-dependent RNA polymerases, which use pUG-tailed RNAs

280 ling those of RNA primases or even canonical RNA-dependent RNA polymerases, while more recent studies

281 ty in RNA viruses has been attributed to the RNA-dependent RNA polymerases, with mutations in RdRps f

282 tically transmitted RNAs coding for putative RNA-dependent RNA polymerases.

283 ral nucleotide when misincorporated by viral RNA-dependent RNA polymerases.

284 troviral RTs but remarkably similar to viral RNA-dependent RNA polymerases.

285 ovirus 3D(pol) are a common feature of viral RNA-dependent RNA polymerases.

286 amidate prodrug and is known to target viral RNA-dependent RNA polymerases.

287 terfering RNAs (siRNAs) that are produced by RNA-dependent RNA Polymerases.

288 includes Ebola and rabies viruses, catalyze RNA-dependent RNA polymerization with viral ribonucleopr

289 (or Main) protease (3CL(pro)) and the nsp12 RNA-dependent RNA-polymerase (RdRp) are the best charact

290 Using an in vitro assay for the RNA-dependent RNA-polymerase (RdRP) of the arenavirus Ma

291 bed and replicated by the heterotrimeric IAV RNA-dependent RNA-polymerase (RdRp).

292 viral nucleocapsid protein and bound by the RNA-dependent RNA-polymerase (RdRP).

293 The segments encode an RNA-dependent RNA-polymerase, glycoprotein, non-structur

294 The RNA-dependent-RNA polymerase (L) gene revealed phylogene

295 optimization of non-nucleoside dengue viral RNA-dependent-RNA polymerase (RdRp) inhibitors are descr

296 te in access to the genomic RNA by the viral RNA-dependent-RNA polymerase.

297 The viral RNA-dependent-RNA-polymerase (RdRp) is a promising targe

298 angible mechanism for a previously suspected RNA-dependent route of Fluorouracil-mediated cytotoxicit

299 TFs and RBPs, as exemplified by YY1, a known RNA-dependent TF, and RBM25, an RBP involved in splicing

300 ept of RNA dependence, defining a protein as RNA dependent when its interactome depends on RNA.