ライフサイエンスコーパス: RQ

1 RQ and carbohydrate oxidation were inversely related to

2 RQ biosynthesis in bacteria and protists requires ubiqui

3 RQ increased as external O(2) was lowered.

4 RQ is also found in several eukaryotic species that util

5 RQ is an aminoquinone that is structurally similar to ub

6 RQ is not found in humans or other mammals, and therefor

7 RQ is not found in humans or other mammals, and therefor

8 RQ is structurally similar to ubiquinone (coenzyme Q or

9 RQ values were considered in relation to the U.S. Enviro

10 RQ was founded on the apparent independence of extinctio

11 RQ was unaffected by sleep restriction.

12 RQ-less animals (kynu-1 and coq-2e KO) cannot survive hi

13 roup had a slightly higher (0.807 +/- 0.006) RQ than the control group (0.791 +/- 0.005, P = 0.05).

14 ction into the PVN (n = 10) or PFH (n = 10), RQs and locomotor activity were monitored over three hou

15 iture (24-EE), 24-h respiratory quotient (24-RQ), and the oxidation rates of fat and carbohydrate wer

16 At this time, 24-RQ was lowered (P < 0.001), corresponding to a 23% incre

17 with synaptic transmission, Syt1-R398/399Q (RQ), in syt1 null mutant cells.

18 (29 months after imatinib mesylate; median 6 RQ-PCR assays), 23 patients (27%) had disease progressio

19 05] and down-regulation of Cyclin D1 (n = 7; RQ 1 vs. 0.61, P < 0.05) in mesenchymal tissue.

20 nthranilic acid (3HAA), completely abolished RQ biosynthesis but did not affect Q levels.

21 at RQ-dependent ETC confers a key advantage (RQ regeneration) over UQ in sulfide-rich conditions.

22 Aggregate RQs from 2000 to 2017 showed that White patients were co

23 0-40 min of treatment, PFH NPY did not alter RQ at any of the doses tested.

24 Although RQ of women faculty increased for most institutions (127

25 CA-CF, but fruit stored under DCA-RQ 1.5 and RQ 2.0 also showed higher amounts of key volatile compou

26 ociations between individual fatty acids and RQ and REE, our findings imply that PUFAs might prevent

27 8.2+/-5.0 to 35.4+/-9.5 microgram/beat, and RQ increased by 23% (all P<0.05).

28 and undetectable BCR-ABL1 by both ddPCR and RQ-PCR was 10.3% (9 of 87) (P .001).

29 ain outcome measures included resting EE and RQ (ventilated hood technique), body composition (dual-e

30 Measures included EE and RQ during the sleep episode on day 2 and continuously ov

31 sma GLP-1 concentrations with resting EE and RQ.

32 not made or used by any parasitic hosts and RQ synthesis is thus an ideal target for anthelmintics.

33 Remarkably, LR and RQ variants disrupt RGS14 binding to Gai1-GDP and XPO1,

34 Remarkably, LR and RQ variants disrupt RGS14 binding to Galphai1-GDP and XP

35 -timepoint analysis, BM outperformed PB, and RQ-PCR was more reliable, while nested PCR appeared appl

36 ic genes coq-5 and coq-6 affected both Q and RQ levels, indicating that both biosynthetic pathways sh

37 RMR and RQ did not change significantly from baseline to day 21,

38 based genome-wide autosomal scans on RMR and RQ phenotypes, obtained from indirect calorimetry, were

39 ) contributing to the variability in RMR and RQ.

40 In lean adolescents, 24-h RQ and RQ during SEE decreased (both P < 0.01) and fat oxidatio

41 es in EE (EEchamber), sleeping EE (SEE), and RQ.

42 ed (VO2), carbon dioxide produced (VCO2) and RQ (VCO2/VO2).

43 R, VO2, VCO2, and RQ were measured at FIO2 0.3 or 1.0.

44 refore, a real-time quantitative TRAP assay (RQ-TRAP) was optimized in the present study and evaluate

45 Because RQ is absent in mammalian hosts of helminths, inhibition

46 (FRET) between 605QD and Cy5 and Iowa Black RQ, we develop a single-QD-based aptameric sensor that i

47 a high throughput assay for drugs that block RQ-dependent metabolism.

48 w RQ is made and no drugs are known to block RQ synthesis.

49 tive correlation with GDR regardless of BMI, RQ, or sex but became nonsignificant in T2DM.

50 e significantly from baseline to day 21, but RQ decreased on day 22 (P < 0.001), which resulted in an

51 s 50.0% (14 of 28), undetectable BCR-ABL1 by RQ-PCR but detectable by ddPCR was 64.3% (36 of 56), and

52 Detectable BCR-ABL1 by RQ-PCR or ddPCR at the time of TKI discontinuation was a

53 nce for patients with detectable BCR-ABL1 by RQ-PCR was 50.0% (14 of 28), undetectable BCR-ABL1 by RQ

54 imitations in the datasets used to calculate RQs revealed important gaps in which future research sho

55 ated conditions (lower postprandial or clamp RQ).

56 In conclusion, RQ-TRAP provides a new tool for the rapid and reliable q

57 ls with serum creatinine inclusion criteria (RQ 0.40 vs. 0.86, P=0.034).

58 Crucially RQ is not made or used by any parasitic hosts and RQ syn

59 DCA - RQ storage was associated with the activation of the alc

60 uotient dynamic controlled atmosphere (DCA - RQ), which induces ethanol production through low oxygen

61 e monitored by respiratory quotient 1.3 (DCA-RQ 1.3) showed lower ethylene production, respiration ra

62 e monitored by respiratory quotient 1.5 (DCA-RQ 1.5) increased the acetaldehyde, ethanol and ethyl ac

63 The apples were stored in DCA-RQ, a new technology for storing fruits, and were compar

64 phere monitored by respiratory quotient (DCA-RQ) and chlorophyll fluorescence (DCA-CF) on anaerobic m

65 cence (DCA-CF) and respiratory quotient (DCA-RQ) on the quality and volatile profile of 'Royal Gala'

66 phere monitored by respiratory quotient (DCA-RQ) with three fruit maturity stages at harvest (early h

67 The storage of 'Galaxy' apple under DCA-RQ 1.3 is efficient in keeping quality regardless of the

68 red under DCA-CF, but fruit stored under DCA-RQ 1.5 and RQ 2.0 also showed higher amounts of key vola

69 Fruit stored under DCA-RQ 2.0 accumulated the highest amounts of anaerobic meta

70 (89 +/- 14 kcal/d, P < 0.0001) and decreased RQ (-0.111 +/- 0.003, P < 0.0001).

71 Inspired 100% O2 increased VO2 and decreased RQ, which might be more remarkable when midazolam/fentan

72 at all times studied and reliably decreased RQ within 30 min of infusion.

73 RQ and 10 institutions [6.9%] with decreased RQ).

74 diabetic versus nondiabetic subjects (Delta RQ 0.06 +/- 0.01 vs. 0.10 +/- 0.01, respectively, P < 0.

75 ture was calculated using chamber-determined RQ either unadjusted (EEDLW) or adjusted (EEDLWDeltaRQ)

76 ASTRO-D2KO mice also exhibited lower diurnal RQ and greater contribution of fatty acid oxidation to e

77 Compared with EBL, RQ decreased on average by 9% during fasting and by 4% d

78 tis elegans COQ-2e is required for efficient RQ synthesis and survival in cyanide.

79 However, NPY reliably enhanced RQs from 30 to 120 min of testing.

80 indicate representation that was equivalent (RQ of 1), higher (RQ greater than 1), or lower (RQ less

81 protonated semiquinone (i.e., k(2)AB = k(ET)(RQ) = 2 x 10(4) s(-)(1)).

82 Faculty RQ increased in 9 of 12 subgroups, but Cambodian America

83 Fasting RQ and DeltaRQ, reflecting metabolic flexibility, did no

84 When we adjusted fasting RQ for percentage body fat and age, the reduced-obese gr

85 lower fasting fat oxidation (higher fasting RQ) and/or an impaired ability to oxidize carbohydrate d

86 o dietary risk was observed due to fipronil (RQ(d) < 1) 5 days after application.

87 Our study reveals that two pathways for RQ biosynthesis have independently evolved.

88 In contrast, Q is not a precursor for RQ biosynthesis in animals such as parasitic helminths,

89 urenine pathway are essential precursors for RQ biosynthesis de novo Deletion of kynu-1, encoding a k

90 rate the key amine-containing precursors for RQ synthesis.

91 To identify a gene specifically required for RQ biosynthesis, we determined the complete genome seque

92 t gene to be discovered that is required for RQ biosynthesis.

93 further validate the requirement of rquA for RQ biosynthesis, we generated a deletion mutant from wil

94 d REE (R(2) ~ 0.9) but were unacceptable for RQ (R(2) = 0.3), Gox, and Fox (R(2) = 0.2).

95 ncy virus strain SIVmac239 were changed from RQ to YE, the resultant virus was able to replicate in p

96 l strain SIVmac239 bearing the mutation from RQ to YE (YE-Nef) both induce an acute lethal disease in

97 he mutation causes an arginine-to-glutamine (RQ) substitution within the first cGMP-binding pocket in

98 In lean adolescents, 24-h RQ and RQ during SEE decreased (both P < 0.01) and fat o

99 lexibility was defined as the change in 24-h RQ from EBL during fasting and standard overfeeding (STO

100 The 24-h respiratory quotient (24-h RQ) and 24-h carbohydrate balance (24-h CHO-Bal) are pre

101 The 24-h RQ, 24-h carbohydrate oxidation (24-h CHO-Ox), and 24-h

102 erved region is as follows: block I, [NX]-H-[RQ]-S-X-[LYIM]-D; block II, G-X-[IF]-F-I-[RD]-R; block I

103 can faculty: mean [SD], RQ, 0.59 [0.08]) had RQs less than 1.

104 , Indian American, and Chinese American, had RQs greater than 1 (eg, Chinese American graduates: mean

105 gotes (C/C) for the ADIPOR1 SNP had a higher RQ (P = 0.003) and greater overall (P < 0.03) and abdomi

106 ation that was equivalent (RQ of 1), higher (RQ greater than 1), or lower (RQ less than 1) than expec

107 However, little is known about how RQ is made and no drugs are known to block RQ synthesis.

108 udy is a key first step in understanding how RQ is made in parasitic helminths.

109 KI to minimize Hg(2+) interference; however, RQ-2 selectively detects Au(3+) without any interference

110 Absolute total change in RQ of URM showed an increase; however, the 30-year slope

111 ction < 0.001) in relation to 2-y changes in RQ.

112 A smaller decrease in RQ, reflecting a smaller increase in lipid oxidation rat

113 s seizure, and sudden death were detected in RQ/+ mutant mice in vivo; however, when provoked, cortic

114 cantly associated with a greater increase in RQ (P = 0.01) but was not related to changes in RMR and

115 Similarly, UCN blocked the increase in RQ elicited by NPY alone.

116 mouse exhibited sustained (24 h) increase in RQ values, increased food intake, tolerance to glucose,

117 o the PVN evoked dose-dependent increases in RQ within 30-40 min of treatment, PFH NPY did not alter

118 ted feeding and evoked reliable increases in RQ.

119 antly associated with a greater reduction in RQ (P = 0.03) and a greater increase in RMR and RMR/kg (

120 acteria, where amination is the last step in RQ biosynthesis, in worms the pathway begins with the ar

121 as a model animal to elucidate key steps in RQ biosynthesis.

122 EE were observed, nor were there changes in RQs after NE or MUS.

123 quire rhodoquinone (RQ) and greatly increase RQ levels.

124 Both ghrelin and NPY increased RQ, indicating enhanced utilization of carbohydrates and

125 The increased RQ in roots in response to declining external O(2) highl

126 rved (57 institutions [39.6%] with increased RQ and 10 institutions [6.9%] with decreased RQ).

127 However, when individual RQs were aggregated into a risk index, most stream reach

128 QTL influencing RQ were found on chromosomes 12q13 (1.65) and 14q22 (1.8

129 x kg(-1) x d(-1) with epinephrine infusion; RQ: 0.832 +/- 0.012 with saline infusion and 0.879 +/- 0

130 Increased resting fat metabolism (i.e., low RQ) and obesity were observed to independently promote a

131 ADIPOR1 T and ADIPOR2 G alleles) had a lower RQ than did the rare homozygotes.

132 Asian residents had lower RQs in counties with more MSIs (mean [SD] RQ, 6.00 [0.65

133 of 1), higher (RQ greater than 1), or lower (RQ less than 1) than expected representation based on US

134 C. elegans makes RQ and can use RQ-dependent metabolic pathways - here, w

135 e and linear regression models assessed mean RQ differences by career stage and over time, with Bonfe

136 ents (median RQ 0.19), AIAN patients (median RQ 0.00), and Hispanic patients (median RQ 0.26) were un

137 ients (median RQ 0.54), API patients (median RQ 0.19), AIAN patients (median RQ 0.00), and Hispanic p

138 dian RQ 0.00), and Hispanic patients (median RQ 0.26) were underrepresented.

139 Black patients (median RQ 0.54), API patients (median RQ 0.19), AIAN patients (

140 In contrast, the median RQ of Hispanic faculty decreased from 0.44 (IQR, 0.19-1.

141 equired intermediate for the biosynthesis of RQ in R. rubrum.

142 d assays were monitored for the formation of RQ(3).

143 ith R. rubrum used for the identification of RQ biosynthetic intermediates.

144 ith BCR-ABL, and underline the importance of RQ-PCR monitoring to guide management using molecularly

145 mammalian hosts of helminths, inhibition of RQ biosynthesis may have potential utility for targeting

146 uffered soils had the greatest proportion of RQs > 1.0.

147 or diet-specific energy imbalance effects on RQ erroneously suggest that low-carbohydrate diets subst

148 eating and blocked the peptide's effects on RQ.

149 using a DCA system, based either on CF or on RQ, to save electrical energy.

150 ) potentiated the effect of NPY (25 pmol) on RQ and food intake, these responses were inhibited by pr

151 Sensitive MRD detection using MFC and/or RQ-PCR has become feasible in virtually all AML patients

152 age-related changes in energy expenditure or RQ.

153 Here we report that RGS14 encoding LR or RQ profoundly impacts protein functions in hippocampal n

154 xists towards algae and soil macro-organism (RQs > 1), but for earthworms it was safe (RQs < 1).

155 ent of optimized real-time quantitative PCR (RQ-PCR) assays for WT1 (commonly overexpressed and a put

156 ethods including real-time quantitative PCR (RQ-PCR) for abnormal fusion transcripts, RQ-PCR for prot

157 Protein tyrosine phosphatase RQ (PTPRQ) was initially identified as a protein tyrosin

158 phosphorylation of the PKG1alpha or PKG1beta RQ variant isolated from transiently transfected 293T ce

159 hrine infusion ended, but the postabsorptive RQ remained modestly elevated.

160 1 (sFRP-1) [n = 12; relative quantification (RQ) 1 vs. 2.33, P < 0.05] and down-regulation of Cyclin

161 Analysis of relative quantification (RQ) ratios of mGlu2 and mGlu3 mRNA expression revealed a

162 Red Queen (RQ) theory states that adaptation does not protect speci

163 Representation Quotient (RQ) was defined as the proportion of trial participants

164 reflected an apparent respiratory quotient (RQ) < 1.

165 Respiratory quotient (RQ) and resting metabolic rate (RMR) were measured.

166 In obese adolescents, respiratory quotient (RQ) and substrate oxidation also did not change.

167 ved measurement of the respiratory quotient (RQ) by indirect calorimetry during the fasted to fed tra

168 ailment on 24-h EE and respiratory quotient (RQ) by using whole-room indirect calorimetry under fixed

169 energy expenditure and respiratory quotient (RQ) in a whole-room calorimeter during energy balance (E

170 tabolic rate (RMR) and respiratory quotient (RQ) represent candidate genes for obesity, type 2 diabet

171 d on the nitrogen-free respiratory quotient (RQ) revealed fat oxidation to be significantly increased

172 correctly estimate the respiratory quotient (RQ) used in the DLW calculations.

173 ied by determining the respiratory quotient (RQ) using indirect calorimetry.

174 aluate the appropriate respiratory quotient (RQ) value to achieve a safe lowest oxygen limit (LOL), d

175 Respiratory quotient (RQ) was calculated as V(CO2)/V(O2).

176 REE and the respiratory quotient (RQ) were measured by indirect calorimetry in the postabs

177 esting metabolic rate, respiratory quotient (RQ), and adiposity-related phenotypes.

178 ed with changes in EE, respiratory quotient (RQ), and body composition.

179 or body mass (AEE/BM), respiratory quotient (RQ), and carbohydrate oxidation with QS and SWS during n

180 rgy expenditure (REE), respiratory quotient (RQ), glucose/carbohydrate oxidation (Gox), and fat oxida

181 ed by BMI, the resting respiratory quotient (RQ), T2DM, and sex.

182 metabolic rate (RMR), respiratory quotient (RQ), temperature, fasting serum glucose, insulin, free f

183 ected in reductions in respiratory quotient (RQ).

184 ubstrate oxidation-ie, respiratory quotient (RQ).

185 ing and alterations in respiratory quotient (RQ).

186 The respiratory quotient (RQ; CO(2) produced : O(2) consumed) is expected to incre

187 (VCO(2); liters), the respiratory quotient (RQ; VCO(2)/VO(2)) and EXEE (kcal), were calculated.

188 iratory exchange rate (respiratory quotient [RQ]) and decreases food intake.

189 to glucose (change in respiratory quotient [RQ]) was mainly related to insulin-stimulated glucose di

190 Representation quotients (RQ) were calculated to describe the relative proportion

191 Representation quotients (RQ) were used to indicate representation that was equiva

192 Main outcomes were representation quotients (RQs) or the ratio of the proportion of IM residents and

193 nt changes in resting respiratory quotients (RQs) in normal (Baseline: 0.78+/-0.03; Depleted: 0.69+/-

194 expenditure (EE) and respiratory quotients (RQs) in the absence of food were made over 2 h in parall

195 ting and postprandial respiratory quotients (RQs), or rate of lipolysis.

196 d in order to compute respiratory quotients (RQs).

197 l have significant pollution risk quotients (RQs > 1), indicating ecotoxicological concerns.

198 mixture were evaluated using risk quotients (RQs) based on measured or predicted environmental concen

199 Risk quotients (RQs) were calculated on the basis of a dietary Hg exposu

200 vidence for effects in fish, risk quotients (RQs) were derived from laboratory-based studies for a se

201 ind that a human leaky RyR2 mutation, R176Q (RQ), alters neurotransmitter release probability in mice

202 ified genetic variants L505R (LR) and R507Q (RQ) located within the nuclear export sequence (NES) of

203 ing an internationally standardized PML-RARA RQ-PCR assay has been successfully used to guide molecul

204 2 polymorphisms with resting metabolic rate, RQ, and body mass index, percentage body fat, sum of 6 s

205 time quantitative polymerase chain reaction (RQ-PCR) analysis to determine whether frequent monitorin

206 time quantitative polymerase chain reaction (RQ-PCR) assays to detect leukemia-specific transcripts (

207 time quantitative-polymerase chain reaction (RQ-PCR) assays were developed and evaluated in samples a

208 time quantitative polymerase chain reaction (RQ-PCR) measurement of Epstein-Barr viral load, we used

209 time quantitative polymerase chain reaction (RQ-PCR) provides information for patient stratification

210 time quantitative polymerase chain reaction (RQ-PCR)-based MRD detection via antigen-receptor rearran

211 time quantitative polymerase chain reaction (RQ-PCR).

212 time quantitative polymerase chain reaction (RQ-PCR); 186 were found to have the bcl-2 rearrangement

213 itative real-time polymerase chain reaction [RQ-PCR]).

214 t converts KYN to 3HKYN, drastically reduced RQ but not Q levels.

215 ng young species does not necessarily refute RQ or require a special explanation but can instead be p

216 We show that C. elegans requires RQ for survival in hypoxic conditions and, finally, we e

217 Cambodian American trainees, with a resident RQ of 0 in 8 of 25 and 4 of 25 specialties, respectively

218 with resistance near the quantum resistance RQ = h/e2, where h is Planck's constant and e is the ele

219 Rhodoquinone (RQ) is a required cofactor for anaerobic respiration in

220 Rhodoquinone (RQ) is an important cofactor used in the anaerobic energ

221 hain; and a laterally acquired rhodoquinone (RQ) biosynthesis enzyme.

222 Here, we identify rhodoquinone (RQ), an electron carrier detected in mitochondria purifi

223 inside the host, they require rhodoquinone (RQ) and greatly increase RQ levels.

224 bic metabolism - this requires rhodoquinone (RQ), an electron carrier that is made by very few animal

225 ctron transport chain in which rhodoquinone (RQ) is required for fumarate reduction and ATP productio

226 ve Q(10) in the Q(B) site with rhodoquinone (RQ), which has a higher pK(a), we were able to observe t

227 m (RQs > 1), but for earthworms it was safe (RQs < 1).

228 Average pollen sample RQ values were above the EFSA chronic LOC in 92.9% of fa

229 Landscape analyses indicated that sample RQ was positively correlated with the abundance of apple

230 sented in counties with more AHCs (mean [SD] RQ, 0.00 [0.06]; P < .001).

231 ean [SD] RQ, 0.19 [0.24]; P = .04; mean [SD] RQ, 0.15 [0.04]; P < .001, respectively), and Hispanic o

232 tation in counties with more MSIs (mean [SD] RQ, 0.19 [0.24]; P = .04; mean [SD] RQ, 0.15 [0.04]; P <

233 remained largely underrepresented (mean [SD] RQ, 0.2 [0.2] for both).

234 ies with greater presence of AHCs (mean [SD] RQ, 0.77 [0.04]; P = .007).

235 were high among home health aides (mean [SD] RQ, 4.1 [1.5] and 2.7 [0.5], respectively).

236 with high relative representation (mean [SD] RQ, 5.6 (0.3) and 2.9 [0.4], respectively).

237 er RQs in counties with more MSIs (mean [SD] RQ, 6.00 [0.65]; P < .001), and White residents had high

238 e highest relative representation (mean [SD] RQ, 8.9 [0.9] and 7.8 [0.9], respectively).

239 (eg, Vietnamese American faculty: mean [SD], RQ, 0.59 [0.08]) had RQs less than 1.

240 (eg, Filipino American graduates: mean [SD], RQ, 0.93 [0.06]) at almost every career stage.

241 (eg, Chinese American graduates: mean [SD], RQ, 3.90 [0.21]), the RQs were less than 1 for Laotian,

242 0.09 [0.20]), Hispanic and Latinx (mean [SE] RQ, 0.00 [0.04]), and Native Hawaiian and other Pacific

243 American Indian and Alaska Native (mean [SE] RQ, 0.00 [0.04]), Black (mean [SE] RQ, 0.09 [0.20]), His

244 waiian and other Pacific Islander (mean [SE] RQ, 0.00 [0.26]) residents were grossly underrepresented

245 mean [SE] RQ, 0.00 [0.04]), Black (mean [SE] RQ, 0.09 [0.20]), Hispanic and Latinx (mean [SE] RQ, 0.0

246 Rigorous sequential RQ-PCR monitoring provides the strongest predictor of RF

247 No significant RQ changes were observed over time for Laotian American

248 DA neurons using iPSC-derived SJ1 KO and SJ1(RQ)KI DA neurons and their isogenic controls.

249 factors observed at synapses of cultured SJ1(RQ)KI neurons was more severe in double-mutant neurons.

250 humans and neurological defects in mice (SJ1(RQ)KI mice).

251 mice carrying the SJ1 patient mutation (SJ1(RQ)KI) exhibit PD features, while Sac2 knockout mice (Sa

252 Further analysis of cilia of SJ1(RQ)DA neurons revealed abnormal accumulation of the Ca(2

253 nerve terminals at an earlier stage than SJ1(RQ)KI mice.

254 The soil RQ values indicated low level of risk to earthworms and

255 ety profile and relative risks of [(18)F]SPA-RQ with 3 different methods of image analysis.

256 P antagonist-receptor quantifier ([(18)F]SPA-RQ) [2-fluoromethoxy-5-(5-trifluoromethyl-tetrazol-1-yl)

257 f 192 +/- 7 MBq (5.2 +/- 0.2 mCi) [(18)F]SPA-RQ.

258 sma were useful as material for EBV-specific RQ-PCR in immunosuppressed patients and nonimmunosuppres

259 hcKO mice also had higher (P<0.05) fed state RQ values than WT animals at 22 degrees C, consistent wi

260 UcnI alone suppressed RQ responses.

261 t grow anaerobically and does not synthesize RQ, and compared it with that of a spontaneous revertant

262 xon is only found in species that synthesize RQ.

263 and has recovered the ability to synthesize RQ.

264 smid-complemented F11 was able to synthesize RQ.

265 trastructural morphometry revealed that Syt1-RQ fully restored the docking defect observed previously

266 However, unlike Syt1-wt, Syt1-RQ-induced docking was strictly PI(4,5)P2-dependent.

267 he most common spider species using targeted RQ-PCR to quantify the potential efficiency of spiders a

268 that sqrd-1 uses both benzoquinones and that RQ-dependent ETC confers a key advantage (RQ regeneratio

269 In this study, we demonstrate that RQ is essential for survival in sulfide.

270 Our study reveals that RQ delays killing by the HCN-producing bacteria Pseudomo

271 The latter observation suggests that RQ is an electron carrier of a fumarate reductase-type c

272 for this increase in REE, determined by the RQ, was from increased carbohydrate oxidation, not from

273 and were thus eligible for inclusion in the RQ-PCR analysis.

274 antly increased REE by 12% and increased the RQ.

275 odimers partly reduces basal activity of the RQ chain.

276 icating that increased basal activity of the RQ variants in cells was not driven by PKG1 autophosphor

277 Finally, overexpressing the RQ-mutant in wild type cells produced no effect on eithe

278 In vitro studies revealed that the RQ mutation selectively strengthened excitatory, but not

279 Although we found that the RQ substitution (R177Q in PKG1alpha and R192Q in PKG1bet

280 gen/deuterium-exchange MS, we found that the RQ substitution causes PKG1beta to adopt an active confo

281 We conclude that the RQ substitution in PKG1 increases its basal activity by

282 entified the molecular mechanism whereby the RQ mutation increases basal kinase activity in the human

283 and 48% lower, respectively, in men with the RQ genotype than in men with the RR genotype but increas

284 graduates: mean [SD], RQ, 3.90 [0.21]), the RQs were less than 1 for Laotian, Cambodian, and Filipin

285 O(2) consumption, CO(2) production, and thus RQ, were taken for roots with declining O(2) .

286 ients with sensitivities at least similar to RQ-PCR (</=10(-5)), if sufficient cells (>4 x 10(6), pre

287 We previously showed the switch from UQ to RQ synthesis is driven by a change of substrates by the

288 We conclude helminths switch from UQ to RQ synthesis principally via changes in the alternative

289 CR (RQ-PCR) for abnormal fusion transcripts, RQ-PCR for proteins known to be overexpressed in AML suc

290 50th percentile institutional ranking by URM RQ with county vs national comparisons.

291 C. elegans makes RQ and can use RQ-dependent metabolic pathways - here, we use C. elegan

292 and caspase-3 expression was evaluated using RQ-PCR, immunohistochemistry, or Western blot.

293 s and aging on EE and substrate utilization (RQ) in p66 Shc-/- (ShcKO) and wild-type (WT) mice.

294 tory actions on LTP induction, while variant RQ exhibits a mixed phenotype.

295 R2 (ie, IVS1 -1352G-->A) was associated with RQ (P = 0.03 and 0.04, respectively), and the associatio

296 Comparison with RQ-PCR-based MRD data showed a clear positive relation b

297 composition) and negatively correlated with RQ (after adjustment for age, sex, and percentage body f

298 SCD-1 were weakly inversely correlated with RQ but could not explain a lower liver fat content.

299 sults confirm the PAET mechanism in RCs with RQ and give strong support that this mechanism is active

300 zipper, and we show that the WT chain in WT-RQ heterodimers partly reduces basal activity of the RQ