ライフサイエンスコーパス: SAM

1 SAM triggers the radical SAM reaction to complete the ox

2 SAM was then cycled back to methionine, leading to futil

3 SAMs of n(odd) have a greater degree of structural gauch

4 SAMs of NHCs were also electrochemically deposited on Pt

5 SAMs of NO(2)-functionalized NHCs and dimethyl-benzimida

6 , or (2) bi-/multi-layer adsorption on NH(2) SAM.

7 1500 ng cm(-2) for CH(3), OH, COOH and NH(2) SAMs) were consistent with: space-filling 'side-on' orie

8 'side-on' orientation and unfolding on CH(3) SAM; greater numbers of FN molecules arranged 'end-on' o

9 , while those generated with NH(2) and CH(3) SAMs were largely 'mixed type' (81% and 86%, respectivel

10 In conclusion, we validate MtBzaC as a SAM:hydroxybenzimidazole-riboside methyltransferase (HBI

11 Here, we characterize a SAM-I riboswitch (SAM-I(Xcc)) from the Xanthomonas campe

12 discovered that R. palustris also contains a SAM-dependent methylase, FufM, that produces 9D5-FuFA fr

13 To this end, a SAM vaccine encoding the rabies virus glycoprotein (RVG)

14 These findings identify a SAM-I riboswitch with a dual functioning expression plat

15 Previously, we demonstrated that a SAM domain-containing protein, SAMD14, promotes SCF/prot

16 e and the methyl donor S-adenosylmethionine (SAM) and resulting in loss of dimethylation at lysine 79

17 In radical S-adenosylmethionine (SAM) enzymes, the 5'-dAdo* is formed upon reduction of S

18 S-adenosylmethionine (SAM) is the methyl-donor substrate for DNA and histone m

19 n response to cellular S-adenosylmethionine (SAM) levels.

20 Cbl)-dependent radical S-adenosylmethionine (SAM) methyltransferases catalyze methylation reactions a

21 enzymes of the radical S-adenosylmethionine (SAM) superfamily that harbor one or more auxiliary [4Fe-

22 rs the methyl group of S-adenosylmethionine (SAM) to catalyze the synthesis of epinephrine from norep

23 nd to the methyl donor S-adenosylmethionine (SAM), the reaction product S-adenosylhomocysteine (SAH),

24 oteins is catalyzed by S-adenosylmethionine (SAM)-dependent histone lysine methyltransferases (KMTs),

25 toward hydroxyanthraquinones and S-alkylated SAM analogues and catalyzes efficient installation of re

26 sensitizes chromatin methylation to altered SAM abundance, yet the mechanisms that allow organisms t

27 Structures of both BAM and SAM have now been reported, allowing a comparison and di

28 vely be targeted, in addition to RNA cap and SAM pockets, for antiviral development.

29 l SAM enzymes produce 5'-deoxyadenosine, and SAM-dependent enzymes for polyamine, neurotransmitter an

30 ecies were found in samples from healthy and SAM mothers, although at different proportions, indicati

31 ollected human milk samples from healthy and SAM-suffering mothers, during the course of mastitis and

32 fic metabolic needs of children with HIV and SAM.

33 SAM forms helical head to tail polymers, and SAM-SAM interactions between chromatin-bound Ph/PRC1 are

34 nd metabolic pathways controlled by SIN3 and SAM synthetase (SAM-S) in Drosophila melanogaster Using

35 This analysis revealed that SIN3 and SAM-S regulate overlapping pathways, many of which invol

36 We previously found that in Arabidopsis SAMs, the HAIRY MERISTEM (HAM) family transcription fact

37 ythromycin-resistance methyltransferases are SAM dependent Rossmann fold methyltransferases that conv

38 e end of the reproductive phase the arrested SAM behaves as a dormant meristem, and they strongly sup

39 including SAM synthetase (Sam-S), as well as SAM levels.

40 yers (SAMs) of the wires in Au-SAM-Pt and Au-SAM-graphene junctions, from which the conductance per m

41 sembled monolayers (SAMs) of the wires in Au-SAM-Pt and Au-SAM-graphene junctions, from which the con

42 e two leading mechanistic models for how BAM/SAM function, and offer an outlook on future studies wit

43 forms a hybrid-barrel intermediate with BAM/SAM in route to its biogenesis into the membrane.

44 methodologies for preparation of NHCs-based SAMs either requires inert atmosphere and strong base fo

45 M riboswitches strongly discriminate between SAM and SAH, the SAM/SAH riboswitch responds to both lig

46 Both SAM and SOI have increased in strength and frequency ove

47 Both SAM by-products are metabolized with equal affinity duri

48 S-box (SAM-I) riboswitches, including the riboswitch present in

49 ndpoint and demonstrated that adjunctive BUP/SAM 2 mg/2 mg was superior to placebo (average differenc

50 ion in MADRS-10 scores from baseline for BUP/SAM 2 mg/2 mg versus placebo at multiple timepoints incl

51 es, we report the efficacy and safety of BUP/SAM as adjunctive treatment in patients with MDD and an

52 Overall, BUP/SAM was generally well tolerated, with most adverse even

53 Buprenorphine/samidorphan (BUP/SAM) combination is an investigational opioid system mod

54 Es, occurring in >=5% of patients in the BUP/SAM 2 mg/2 mg treatment group, which was more frequently

55 s reactive than the methyl radical formed by SAM photolysis.

56 e is known to be allosterically inhibited by SAM for decades, but the importance of this regulatory c

57 g the necessity for MTHFR to be regulated by SAM.

58 yltransferase enzymes that utilise a carboxy-SAM (cxSAM) cofactor generated from SAM by a cxSAM synth

59 nown about the underlying mechanisms causing SAM.

60 experiments to elucidate how CysS uses Cbl, SAM, and a [4Fe-4S] cluster to catalyze iterative methyl

61 A [4Fe-4S](+) cluster reductively cleaves SAM to form the Omega organometallic intermediate in whi

62 catalytic binding pockets for the cofactor (SAM) and the substrate (norepinephrine) binding sites.

63 en requiring hospitalization for complicated SAM.

64 teomics data among children with complicated SAM in Kenya and Malawi.

65 Compressing SAM/BAM into CRAM format significantly reduces the space

66 The conserved SAM domain was required for SAMD14 to increase colony-fo

67 In contrast, SAM-S affected only a narrow range of genes and pathways

68 regulate the sequence of events, controlling SAM dual reactivity and preventing unwanted radical-base

69 onalized AFM cantilevers and the OH and COOH SAM surfaces were predominantly 'loop-like' (76% and 94%

70 arranged 'end-on' on OH and especially COOH SAMs; and initial 'side-on' contact, followed by either

71 This study establishes the CRISPR/dCas9 SAM as a powerful tool that enables activation of the en

72 an efficient alternative to iLNPs to deliver SAM vaccines.

73 ase 1 activity, but only chloramine depleted SAM, suggesting that removal of substrate was the most e

74 we substituted its SAM domain with distinct SAM domains predicted to be structurally similar.

75 y or deplete its substrate, the methyl donor SAM.

76 This reaction also drives SAM formation and further depletes ATP reserves.

77 methylated Cap-0 analog m(7)GpppA and either SAM or SAH.

78 atin regulator SIN3 and the metabolic enzyme SAM-S, uncover a complex relationship between metabolism

79 and show SAE is a mechanistically-equivalent SAM-alternative for HydG, both supporting enzymatic turn

80 Mechanistically, we find SAM interacts and stabilizes Sugt1, a co-chaperon protei

81 $K$ estimates for SAM were 9.4 and 5.7 in Burkina Faso and in Mali, respec

82 cern that our current treatment strategy for SAM regardless of HIV status involves a high-fat therape

83 Combined treatment for SAM and MAM is non-inferior to standard care.

84 nd aromatic anthracene cores, and by forming SAMs of the resulting molecules, we clearly demonstrate

85 nd in the active site, but too far away from SAM to be methylated.

86 Lesional skin biopsies from SAM syndrome patients (n = 7) revealed decreased Dsg1 an

87 carboxy-SAM (cxSAM) cofactor generated from SAM by a cxSAM synthase (CmoA).

88 Results from SAM cleavage reactions support the supposition that PT i

89 Having SAM among under-five children was explained by the indiv

90 Altogether, our findings identify SAM as a regulator of SC proliferation through facilitat

91 Here we identify SAM (Sugt1 asssociated muscle) lncRNA that is enriched i

92 not be directly attributed to alterations in SAM levels.

93 s to the observed rural-urban disparities in SAM.

94 tion during life-experienced fluctuations in SAM availability are unknown.

95 cing the flexibility of residues involved in SAM binding and thereby affects the molecular mechanism

96 Bacterial diversity was lower in SAM milk samples, and differences in bacterial compositi

97 est effect on spatial learning and memory in SAM-exposed rats.

98 ht into metabolic dysfunction that occurs in SAM.

99 AM)-binding pocket as well as participate in SAM binding and catalysis.

100 ystery and reveal new, dynamic properties in SAMs of thiols.

101 QI and its influence on thermoelectricity in SAMs represents a critical step toward functional ultra-

102 nfluence on cross-plane thermoelectricity in SAMs.

103 ltiple methionine catabolic genes, including SAM synthetase (Sam-S), as well as SAM levels.

104 how that overexpression of Ph with an intact SAM increases ubiquitylated H2A in cells.

105 this signature of CQI can be translated into SAM-on-gold molecular films.

106 omain function in SAMD14, we substituted its SAM domain with distinct SAM domains predicted to be str

107 The Sorting and Assembly Machinery (SAM) complex consists of three proteins that assemble as

108 , and by the sorting and assembly machinery (SAM) in mitochondria.

109 differentials in severe acute malnutrition (SAM) among under-five children is poorly exploited, oper

110 d $K$ factors for severe acute malnutrition (SAM) and moderate acute malnutrition (MAM) from AM incid

111 Children with severe acute malnutrition (SAM) display immature, altered gut microbiota and have a

112 nts differentiate severe acute malnutrition (SAM) from moderate acute malnutrition (MAM) with differe

113 n presenting with severe acute malnutrition (SAM) in Africa and is associated with increased mortalit

114 Severe acute malnutrition (SAM) is the most serious form of undernutrition, charact

115 hildren developed severe acute malnutrition (SAM).

116 Sub-acute mastitis (SAM) is a prevalent disease among lactating women, being

117 RISPR/dCas9 Synergistic Activation Mediator (SAM) system, which induced robust transcriptional activa

118 he AP2 genes maintain shoot apical meristem (SAM) activity in part by keeping WUSCHEL expression acti

119 nct cell types of the shoot apical meristem (SAM) withstand ultraviolet radiation (UVR) stress can im

120 rtical axis of plant shoot apical meristems (SAMs), stem cells are located at the top while cells spe

121 potent stem cells in shoot apical meristems (SAMs), which continuously produce new aboveground organs

122 echanism-II requires nhr-114 to activate Met/SAM cycle gene expression, the vitamin B12 transporter,

123 and the methionine/S-adenosylmethionine (Met/SAM) cycle.

124 vitamin B12 represses the expression of Met/SAM cycle genes by a propionate-independent mechanism we

125 ism is activated by perturbations in the Met/SAM cycle, genetically or due to low dietary vitamin B12

126 Taken together, Met/SAM cycle activity is sensed and transcriptionally adjus

127 thionine, MMA, metabolites of 1C metabolism (SAM, SAH) and anthropometry were measured.

128 Cysteine, S-adenosyl methionine (SAM) and the formation of an iron-sulfur cluster in DndC

129 g the availability of S-adenosyl methionine (SAM), the essential metabolite for DNMT-catalyzed methyl

130 oli can be fused to a S-adenosyl methionine (SAM)-binding aptamer to generate a red fluorescent RNA-b

131 gue and methyl donor, S-adenosyl methionine (SAM).

132 e knot loops form the S-adenosyl-methionine (SAM)-binding pocket as well as participate in SAM bindin

133 Mutations to the S-adenosyl-l-methionine (SAM) binding motif in the nsp14 abolished the G-N-7 MTas

134 NifB is a radical S-adenosyl-L-methionine (SAM) enzyme that is essential for nitrogenase cofactor a

135 lyase is a radical S-adenosyl-l-methionine (SAM) enzyme with the unusual property that addition of S

136 Radical S-adenosyl-l-methionine (SAM) enzymes initiate biological radical reactions with

137 y canonical radical S-adenosyl-l-methionine (SAM) enzymes involves electron transfer (ET) from [4Fe-4

138 aracterized radical S-adenosyl-l-methionine (SAM) enzymes is increasing, the roles of these enzymes i

139 S-adenosyl-l-methionine (SAM) is a necessary cosubstrate for numerous essential e

140 S-adenosyl-l-methionine (SAM)-dependent methyltransferases (MTs) catalyse the met

141 ture of PCBs, called the School Air Mixture (SAM), to match the profile of an older school from our a

142 lation (ENSO) and the Southern Annular Mode (SAM) are strongly associated with spatially extended dro

143 ation Index (SOI) and Southern Annular Mode (SAM).

144 According to the size-advantage model (SAM), selection should favour sex change when the second

145 -type Dsg1, but not Dsg1 constructs modeling SAM syndrome-causing mutations.

146 the fabrication of self-assembled monolayer (SAM) and the influence of AuNPs on Au chip for Aflatoxin

147 c contact over the self-assembled monolayer (SAM) without chemically damaging the molecules and preve

148 nsfer) of organic self-assembled monolayers (SAMs) chemically anchored to metal surfaces is a challen

149 al conductance of self-assembled monolayers (SAMs) has been investigated.

150 HS/EDC)-activated self-assembled monolayers (SAMs) of 6-mercaptohexanoic acid (MHA).

151 ropose the use of self-assembled monolayers (SAMs) of helical lanthanide-binding peptides.

152 he conductance of self-assembled monolayers (SAMs) of the wires in Au-SAM-Pt and Au-SAM-graphene junc

153 e their ubiquity, self-assembled monolayers (SAMs) of thiols on coinage metals are difficult to study

154 the formation of self-assembled monolayers (SAMs) on various surfaces.

155 ated alkane-thiol self-assembled monolayers (SAMs).

156 While most SAM riboswitches strongly discriminate between SAM and S

157 A conserved Sterile Alpha Motif (SAM) in the Polycomb Repressive Complex 1 (PRC1) subunit

158 Hundreds of sterile alpha-motif (SAM) domains have predicted structural similarities and

159 OA models, (1) senescence accelerated mouse (SAM)-prone 8 (SAMP8) as spontaneous OA model with SAM-re

160 t times up to 10 min, and thus with multiple SAM turnovers, to probe the fate of the 5'-dAdo(*) radic

161 mers with and without glycine, Mycobacterium SAM-IV riboswitch with and without S-adenosylmethionine,

162 distinct conformations, and that addition of SAM or SAH shifts the population into a stable state tha

163 e with the unusual property that addition of SAM to the [4Fe-4S](1+) enzyme absent substrate results

164 ces for close contacts between the S atom of SAM and Tyr68 or between any of the H atoms of the trans

165 SAM in holo MtNifB, suggests the binding of SAM between the RS- and K2-clusters and putative paths f

166 embers require for the reductive cleavage of SAM to afford the common 5'-deoxyadenosyl 5'-radical (5'

167 k to methionine, leading to futile cycles of SAM synthesis and recycling and explaining the necessity

168 ma) and partial (MUAC, edema) definitions of SAM and MAM.

169 Global deletion of SAM has no overt effect on mice but impairs adult muscle

170 Consistently, inducible deletion of SAM in SCs leads to deficiency in muscle regeneration.

171 To elucidate the molecular determinants of SAM domain function in SAMD14, we substituted its SAM do

172 channels, combined with in silico docking of SAM in holo MtNifB, suggests the binding of SAM between

173 K2-clusters and putative paths for entry of SAM and exit of products of SAM cleavage, thereby provid

174 an inequalities in the associated factors of SAM while controlling for individual, household, and nei

175 ort distance of the incoming methyl group of SAM for a direct methyl transfer during catalysis.

176 nd in line with the incoming methyl group of SAM-would allow some SET domain proteins to selectively

177 ent RNA-based sensor that enables imaging of SAM in live mammalian cells.

178 Loss of SAM or Sugt1 both disrupts kinetochore assembly in mitot

179 cant pro-rural (significantly higher odds of SAM in rural areas) inequality while only Tajikistan and

180 otogynous species support the predictions of SAM, protandrous species do not, as they exhibit higher

181 four-chamber views on which the presence of SAM, presence of MR, total stroke volume, and cardiac ma

182 The overall prevalence of SAM among rural children was 4.8% compared with 4.2% amo

183 e rural-urban dichotomy in the prevalence of SAM was generally significant with higher odds found in

184 ths for entry of SAM and exit of products of SAM cleavage, thereby providing important mechanistic in

185 cteria, salvages at least two by-products of SAM-dependent enzymes for carbon and sulfur salvage, con

186 es, the 5'-dAdo* is formed upon reduction of SAM by an [Fe(4)S(4)] cluster.

187 s (HMP-PP), and we outline new subclasses of SAM and tetrahydrofolate-binding RNA regulators.

188 le differences in the overall composition of SAMs and the chemistry of their attachment to surfaces.

189 Junctions made of SAMs of n-alkanethiolates supported by Au were character

190 relate changes in the physical properties of SAMs to photoelectron spectroscopy to unambiguously assi

191 ghts into the structure-property relation of SAMs for the design of ultrathin film dielectrics as wel

192 unctionalized lipoic acid AuNPs deposited on SAM Au chips followed by in situ activation of functiona

193 However, the dose-dependent effects on SAM-dependent metabolism of polyamines and creatine coul

194 anisms of nutritional recovery in HIV and/or SAM are not well understood.

195 has attributes that are distinct from other SAM domains and underlie SAMD14 function as a regulator

196 Ph SAM forms helical head to tail polymers, and SAM-SAM int

197 Ph SAM-dependent condensates can recruit PRC1 from extracts

198 mechanism, here we analyze the effects of Ph SAM on chromatin in vitro.

199 observed 20th-century trend toward positive SAM anomalies concomitant with the weakening of midlatit

200 reports the characterization of prototypical SAMs of n-alkanethiolates on gold (CH(3)(CH(2))(n)SAu, n

201 Radical SAM enzymes produce 5'-deoxyadenosine, and SAM-dependent

202 celeration of radical reactions by a radical SAM enzyme and provides insights into the mechanism by w

203 we report the first evidence that a radical SAM enzyme MoaA accelerates the radical-mediated C-C bon

204 support the supposition that PT is a radical SAM reaction.

205 ytomegalovirus co-opts the antiviral radical SAM enzyme viperin (virus-inhibitory protein, endoplasmi

206 elective X-H bond activation in both radical SAM and adenosylcobalamin enzymes.

207 CysS is a Cbl-dependent radical SAM methyltransferase involved in cystobactamid biosynth

208 of the large family of SPASM domain radical SAM enzymes characterized by the presence of three [4Fe-

209 NifB is an essential radical SAM enzyme required for the assembly of an 8Fe core of t

210 n is also notable as one of very few radical SAM-dependent enzymes present in higher animals; however

211 In radical SAM enzymes, the slow radical initiation step kineticall

212 mediacy of organometallic species in radical SAM enzymes.

213 The radical SAM (RS)-cluster is coordinated by three Cys, and the ad

214 While the role of the radical SAM cluster in generating the 5'-dA(*) is well understoo

215 CN)] synthon is the substrate of the radical SAM enzyme HydE, with the generated 5'-deoxyadenosyl rad

216 Among them, the radical SAM protein NifB plays an essential role, concomitantly

217 SAM triggers the radical SAM reaction to complete the oxygen-sulfur swapping.

218 ortant mechanistic insights into the radical SAM-dependent carbide insertion concomitant with cofacto

219 um Ruminococcus gnavus, requires two radical SAM enzymes (RumMC1 and RumMC2) catalyzing the formation

220 insights into the mechanism by which radical SAM enzymes accelerate radical chemistry.

221 ed posttranslationally by a specific radical-SAM sactisynthase.

222 We have recognized the reduced-SAM R(3)S(0) radical is a ((2)E) state with its antibond

223 florescence- and flower-forming reproductive SAM.

224 ated leaf, and increases in the reproductive SAM via the RNA-dependent DNA methylation pathway.

225 Here, we characterize a SAM-I riboswitch (SAM-I(Xcc)) from the Xanthomonas campestris that regulat

226 hole-genome DNA methylation of isolated rice SAMs in the vegetative and reproductive stages, we show

227 Self-amplifying RNA (SAM) represents a versatile tool that can be used to dev

228 ife of the translational D. indicum metI RNA-SAM complex is significantly shorter than that of the tr

229 itically determines the stability of the RNA-SAM complex by influencing the flexibility of residues i

230 nce of an A or C residue correlates with RNA-SAM complex stability.

231 ures of the SAM/SAH riboswitch bound to SAH, SAM and other variant ligands at high resolution.

232 Thus, the SAMD14 SAM domain has attributes that are distinct from other S

233 SASH1 (SAM and SH3 domain-containing protein 1) is a tumor supp

234 ture indicates that this enzyme has a single SAM binding site, which at this stage is occupied by cys

235 hways controlled by SIN3 and SAM synthetase (SAM-S) in Drosophila melanogaster Using several approach

236 ter degree of structural gauche defects than SAMs of n(even).

237 iochemical and genetic data demonstrate that SAM-I(Xcc) expression platform not only can repress gene

238 Further examination reveals that SAM loss results in a cell-autonomous defect in the prol

239 In vitro and in vivo experiments show that SAM-I(Xcc) controls the met operon primarily at the tran

240 Our work therefore supports that SAM has a bacterial origin, with increased bacterial loa

241 The SAM Au chip was sequentially modified by EDC-NHS crossli

242 The SAM capacitance, dielectric constant, and surface hydrop

243 tionally uncharacterized YfiP protein as the SAM-dependent 3-amino-3-carboxypropyl transferase cataly

244 Under appropriate conditions, the SAM undergoes a developmental transition from a leaf-for

245 A with a truncated Ph protein containing the SAM results in formation of concentrated, phase-separate

246 constricts the backbone as well as forms the SAM-binding pocket with its three distinctive loops, aff

247 ion of the K1-cluster, too far away from the SAM binding site, supports a mechanism in which the K2-c

248 region by NMR spectroscopy, we identify the SAM-binding region and observe changes in the dynamics o

249 enes related to axillary bud dormancy in the SAM and negative regulators of cytokinin signaling.

250 that changes in DNA methylation begin in the SAM long before germ cell differentiation to protect the

251 ine the concentration gradient of HAM in the SAM through activating a group of microRNAs.

252 Stem cells housed in the SAM tip are engaged in genome integrity maintenance and

253 lready undergone CHH hypermethylation in the SAM.

254 ites, should be formally incorporated in the SAM.

255 Here we present synthesis of the SAM analog S-adenosyl-l-ethionine (SAE) and show SAE is

256 We report cryoEM structures of the SAM complex from Myceliophthora thermophila, which show

257 lated in response to UV-B irradiation of the SAM.

258 We have determined crystal structures of the SAM/SAH riboswitch bound to SAH, SAM and other variant l

259 onducting layer is softly deposited over the SAM to protect it during the deposition of the metal ele

260 To protect the SAM from degradation and achieve efficient delivery, lip

261 rongly discriminate between SAM and SAH, the SAM/SAH riboswitch responds to both ligands with similar

262 ropensity as the knot tightens to secure the SAM cofactor.

263 ation and the apical-basal patterning of the SAMs.

264 This SAM-I riboswitch appears to be highly conserved in Xanth

265 do. or .CH(3), and indeed, each of the three SAM S-C bonds can be regioselectively cleaved in an RS e

266 ve QI (CQI) in cross-plane transport through SAMs and assess its influence on cross-plane thermoelect

267 Thus, SAM-induced phase separation, in the context of Ph, can

268 s electron transfer (ET) from [4Fe-4S](+) to SAM, generating an R(3)S(0) radical that undergoes regio

269 ignificant role for epigenetic adaptation to SAM depletion in vivo.

270 ene expression in response to SAM binding to SAM-I(Xcc) aptamer but also can sense and bind uncharged

271 e Sprague-Dawley rats were exposed either to SAM or filtered air in nose-only exposure systems, 4 h/d

272 Finally, mammary epithelial cell exposure to SAM milk pellets showed an over-production of IL8.

273 Time-dependent binding of FN to SAM-coated QCM crystals occurred in at least two phases:

274 y can repress gene expression in response to SAM binding to SAM-I(Xcc) aptamer but also can sense and

275 We identified a robust response to SAM depletion that is highlighted by preferential cytopl

276 lved in methionine metabolism in response to SAM, primarily at the level of transcriptional attenuati

277 strate results in rapid electron transfer to SAM with accompanying homolytic S-C5' bond cleavage.

278 Standard care clinics treated SAM with weight-based RUTF rations, and MAM with ready-t

279 were not significantly different at a 1.5 ug SAM dose.

280 Under SAM-depleted conditions, H3K9 mono-methylation preserves

281 d the effectiveness of a simplified, unified SAM/MAM protocol for children aged 6-59 months.

282 ioselective homolytic S-C bond cleavage upon SAM reduction?

283 al transition from a leaf-forming vegetative SAM to an inflorescence- and flower-forming reproductive

284 ansposable elements (TEs), in the vegetative SAM relative to the differentiated leaf, and increases i

285 , multiple allergies, and metabolic wasting (SAM) syndrome, caused by biallelic desmoglein 1 (DSG1) m

286 We, therefore, examined whether SAM syndrome-causing DSG1 mutations interfere with Cx ex

287 While SAM characteristics are largely altered in this transiti

288 ood (RUTF or RUSF) required for a child with SAM to reach full recovery was less in the combined prot

289 teria: 19 studies included all children with SAM and 9 included specific subgroups of children with S

290 Children with SAM are treated similarly regardless of HIV status, alth

291 in faecal VOC profiles between children with SAM who survived and those who died.

292 of faecal VOCs could identify children with SAM with increased risk of mortality.

293 tors of inpatient mortality in children with SAM.

294 included specific subgroups of children with SAM.

295 ed with inpatient mortality in children with SAM.

296 tity of the cleaved S-C bond correlates with SAM ribose conformation but not with positioning and ori

297 acillus thermodenitrificans SPL (GtSPL) with SAM forms Omega within ~15 ms after mixing.

298 uded children aged <=59 mo hospitalized with SAM and used multivariable analysis to assess the baseli

299 prone 8 (SAMP8) as spontaneous OA model with SAM-resistant 1 (SAMR1) as control; (2) destabilization

300 ntly between patients with and those without SAM (10 mL +/- 4.7 vs 3 mL +/- 2.3; P = .03) and those w