ライフサイエンスコーパス: SBS

9 mportantly, site-directed mutagenesis of 202-SBS or expression of a dominant negative form of STAT3 s

10 AT3 to an oligonucleotide containing the 202-SBS in gel-mobility shift assays and to the 5'-regulator

11 a potential STAT3 DNA-binding site (the 202-SBS) present in the 5'-regulatory region of the Ifi202 g

12 Children with type 2 or 3 SBS had significantly shorter small bowel length than ch

13 trulline concentrations were lower in type 3 SBS but not significantly different: 15 umol/L (11-25 um

14 e previous methods, DeepMS could discover 37 SBS, 5 DBS, and 9 Indel new signatures, many of which re

15 triallyl leucine betaine chloride and 43.5% SBS.

16 ence of HVI among patients with an abdominal SBS and negative findings on CT is extremely low, if not

17 A total of 754 patients with abdominal SBS had an HVI prevalence of 9.2% (n = 69), with only 1

18 ng and observing all patients with abdominal SBS should be reconsidered when a high-quality CT scan i

19 ncluded adult trauma patients with abdominal SBS.

20 l adhesive residue and clinically acceptable SBS.

21 s shows good concordance while acknowledging SBS, ID and copy-number artefacts.

22 ion with a newly-developed eye mask (Activa, SBS Sistemi, Turin, Italy) immediately followed by IPL t

23 potential for spontaneous improvement after SBS in advanced ROP.

24 ce the half-life of SMD targets that form an SBS by either intramolecular or intermolecular base-pair

25 tely 355 nm) in 10 sec, we then performed an SBS reaction on a chip that contains a self-priming DNA

26 An analogous SBS signature, again without biallelic BRCA2 inactivatio

27 arenteral support volume, bowel anatomy, and SBS features.

28 erodimer (SB) and two heterotrimers (BSB and SBS) by alkyne bridges leads to the formation of coupled

29 rial hypertension, dyslipidemia, cancer, and SBS-CIF caused by radiation enteritis, but fewer cases a

30 ice genes use APA, supported by MPSS-DGE and SBS-DGE tags, respectively.

31 main MBS and SBS homomers are different, and SBS homomers are likely to be folded cotranslationally,

32 show that the folds of single-domain MBS and SBS homomers are different, and SBS homomers are likely

33 r dideoxynucleotide terminating reaction and SBS.

34 The SeBSe and SBS pincer ligands can be synthesized via two independen

35 s(4,5)P(2) and that three lysine residues at SBS I site, Lys-1420, Lys-1432, and Lys-1434, are respon

36 we reported a single-molecule nanopore-based SBS strategy that accurately distinguishes four bases by

37 e ovary to uncover genes with an ovary-bound SBS that are misregulated upon Su(Hw) loss.

38 nificantly remodel in the setting of chronic SBS.

39 e function involves binding to non-clustered SBSs and does not require CP190 or Mod67.2.

40 Compared to the Ugandan cohort, SBSs and RIs in the UK cohort were lower at visit 1, and

41 Maximal transactivation of COL7A1 SBS-driven promoters in either MDA-MB-468 carcinoma cell

42 ed SMAD3, but not SMAD2, can bind the COL7A1 SBS.

43 osophila flies and destroys Escherichia coli SBS 363 cells.

44 In contrast, SBS signature 5 increases with time in all cell types, i

45 ubility (SL), shear bond strength to dentin (SBS), and viability of Streptococcus mutans under 14.6 J

46 life seem to be similar to those who develop SBS as adolescents with regards to long-term outcome, de

47 erences between adult patients who developed SBS during early childhood and those who develop this as

48 ised the pediatric group (PG), 37 developing SBS at age 13 to 25 constituted the adolescent group (AG

49 he two groups, pediatric patients developing SBS early in life seem to be similar to those who develo

50 Thirty patients developing SBS younger than 12 years comprised the pediatric group

51 tudy evaluated patients with newly diagnosed SBS-CIF initiating PS between 2015 and 2020 at a nationa

52 pontaneous deamination, and the more diffuse SBS signature 5, which is of unknown etiology.

53 The quantum-enhanced SBS imaging holds promise across diverse fields, such as

54 This ensemble SBS chemistry has been implemented on an existing Illumi

55 Intermittent MGO exposure incites episodic SBS mutations without permanent BRCA2 inactivation.

56 anoids explanted from mice with experimental SBS.

57 Mapping of ovary Su(Hw)(f) SBSs revealed that female fertility requires binding to

58 hort bowel syndrome with intestinal failure (SBS-IF) is a rare but devastating medical condition.

59 hort-bowel syndrome with intestinal failure (SBS-IF) to gain insight into its mechanism of action.

60 hort bowel syndrome with intestinal failure (SBS-IF).

61 d underwent a SRSB between 1985 and 2010 for SBS were included.

62 odipy-FL-510, as a reversible terminator for SBS.

63 -s-indacene), as a reversible terminator for SBS.

64 tide analogues as reversible terminators for SBS.

65 c supplementation as a potential therapy for SBS and describe a xenotransplantation model that provid

66 inical trials as a potential new therapy for SBS and is the only hGLP-2 analogue in clinical testing

67 d by a single excitonic state but by two for SBS.

68 d with clinically used PA gel yielded higher SBS than the BCA/BPA etchants, it exhibited greater adhe

69 Human SBSs can form by intermolecular base-pairing between a 3

70 dNTP-azidolinker-fluorophores for the hybrid SBS.

71 ead length of >30 bases by using this hybrid SBS method on a chip and a four-color fluorescence scann

72 In SBS patients disaccharidases and peptidases can be upreg

73 In SBS, the remaining SB may dilate as part of intestinal a

74 In SBS-IF patients, feeding fails to decrease proteolysis i

75 Gut adaptation in SBS patients does not appear to involve an increase in g

76 -dNTPs-allyl-fluorophore, for application in SBS.

77 ome parenteral nutrition (HPN) dependence in SBS patients with intestinal failure.

78 We find no detectable increase in SBS signature 1 mutations in neurons and only a very wea

79 A significant increase in SBS was measured for all samples when the self-etch syst

80 SS OCT can provide useful information in SBS, revealing a wide variety of vitreoretinal interface

81 orthy deceleration of growth was observed in SBS children 6 mo after weaning off HPN.

82 Up-regulation of colonic PepT1 in SBS may adaptively improve accrual of malabsorbed di- an

83 illus resp. low amounts of Proteobacteria in SBS patients with preservation of colon and ileocecal va

84 hat the evolution of quaternary structure in SBS homomers is significantly influenced by stochastic p

85 longed PN duration and decreased survival in SBS children.

86 in the duodenum and colon is upregulated in SBS patients.

87 Altogether, our data suggest that MHA, SBS, FTNS, EPS, and APSM comprise a phenotypic spectrum

88 s of SI, LPH, and ApN in colonocytes in most SBS patients with large variation and strongest effect f

89 For A-tracts, most SBSs occur in the direction of the base-pair flanking th

90 sponding mutants with a single SBS, multiple SBSs probably interact to cause the high affinity bindin

91 Because some Byr4 mutants with multiple SBSs bound Spg1 tighter than the corresponding mutants w

92 ould yield a single-molecule electronic Nano-SBS platform.

93 nanopore-based sequencing by synthesis (Nano-SBS) strategy that can accurately distinguish four bases

94 ucleotide-based polymers to perform nanopore SBS on an alpha-hemolysin nanopore array platform.

95 pore-based sequencing-by-synthesis (Nanopore-SBS) approach, which used a set of nucleotides with poly

96 a nanopore, in combination with the Nanopore-SBS approach, can provide the foundation for a low-cost,

97 d in duodenal and colonic biopsies from nine SBS patients in a late stage of adaptation as well as he

98 body mass index (BMI)-matched controls (non-SBS), for 14 d with the DLW method.

99 n values for age-, BMI-, and sex-matched non-SBS controls.

100 175 kcal/d, P = 0.001) and also for the non-SBS group (2393 +/- 445 compared with 1532 +/- 178 kcal/

101 antly lower in the SBS group than in the non-SBS group (P < 0.01); however, predicted TEE did not dif

102 The 5-y survival rates in nonmalignant SBS-IF patients who initiated HPS were 89.1% for those a

103 ort the melt-phase self-assembly behavior of SBS triblock copolymers (S = poly(styrene) and B = poly(

104 The most common cause of SBS in the AG was trauma (n=13), followed by tumors (n=7

105 the abundance of PepT1 mRNA in the colon of SBS patients was more than 5-fold that in control subjec

106 Each cycle of SBS consists of the incorporation of the photocleavable

107 NA template, facilitating the development of SBS as a viable approach for high-throughput DNA sequenc

108 SB diameter of SBS children (n = 61) was measured in contrast SB series

109 ol reported in indoor air during episodes of SBS; (2) acute exposure to 2,2,4-trimethyl-1,3-pentanedi

110 shown to improve survival and weight gain of SBS mice and increase the proliferation of intestinal cr

111 of GLP-2 coinfused with PN in a rat model of SBS (60% jejunoileal resection plus cecectomy).

112 study reviews outcomes of a large number of SBS infants and identifies predictors of success.

113 f administration in relation to the onset of SBS, optimal patient selection for use, duration of trea

114 nfants who have liver failure as a result of SBS are frequently referred for consideration for combin

115 permanent sequelae are rare, the symptoms of SBS can be uncomfortable, even disabling, and whole work

116 ould be interpreted according to the type of SBS.

117 curcumin had minimal impact on either FS or SBS, but detectably increased WS and SL.

118 Solid bleached sulphate paperboard (SBS) and polyethylene terephthalate polymer (PET) substr

119 Pediatric SBS carries extensive morbidity and high mortality, but

120 zards analysis was conducted on 80 pediatric SBS patients.

121 t to calculate the total costs for pediatric SBS patients and to provide an in-depth analysis of thes

122 This is particularly true for pediatric SBS patients who receive some of the most complex medica

123 an (+/- SD) total cost of care for pediatric SBS was US$505 250 +/- US$248 398 (corrected for inflati

124 e major predictors of mortality in pediatric SBS.

125 The comprehensive care of pediatric SBS patients costs significantly more than has previousl

126 t better prediction of outcomes of pediatric SBS, which may help to direct future management of these

127 le fluorescent dideoxynucleotides to perform SBS.

128 R322 using an r-m+ M5a1 derivative and phage SBS for screening.

129 ) </= 0.82, we demonstrate that polydisperse SBS triblock copolymers self-assemble into periodic stru

130 yrene-block-polybutadiene-block-polystyrene (SBS) polymer have been produced.

131 The porous SBS substrate is allowed approximately 20% less ink usag

132 cept to being both affordable and practical, SBS needed to overcome a series of challenges, each of w

133 he disease progressed to stage 4B, prompting SBS at 39 weeks PMA.

134 proteins, even though both localize to Rbp9 SBSs.

135 A RNA editing signatures into COSMICv3.4 RNA-SBS reference signatures.

136 e, we provide the first validation of an RNA-SBS mutational signature by decomposing novel exogenous

137 Additionally, we have identified novel RNA-SBS signatures for APOBEC1, APOBEC3B, and APOBEC3G.

138 Recently, RNA single base substitution (RNA-SBS) signatures were defined and described by decomposin

139 luenced by cellular factors, on a fine scale SBSs are influenced by the local DNA sequence-context, a

140 Whereas on a genome-wide scale SBSs are influenced by cellular factors, on a fine scale

141 reshold for stimulated Brillouin scattering (SBS) by an order of magnitude, whilst simultaneously con

142 ht-enhanced stimulated Brillouin scattering (SBS) imaging contrast, the signal-to-noise ratio is sign

143 Stimulated Brillouin scattering (SBS) is a promising approach to realize highly coherent

144 intermodal stimulated Brillouin scattering (SBS) mediated by long-lived flexural acoustic waves.

145 Each participant's sexual behavior score (SBS) was estimated based on the number and type of unpro

146 aly (MHA) and Fechtner (FTNS) and Sebastian (SBS) syndromes are autosomal dominant platelet disorders

147 In well selected SBS patients, outcomes as diverse as survival, macronutr

148 demonstrate that the SMAD binding sequence (SBS) representing the TGF-beta response element in the r

149 P), we identified 24 SlmA-binding sequences (SBSs) on the chromosome.

150 on electron microscopy analyses of seventeen SBS triblock copolymers with poly(1,4-butadiene) volume

151 Abdominal seat belt sign (SBS) has historically entailed admission and observation

152 ions, discovered a new mutational signature (SBS-RT), recognized an oxidative phosphorylation (OXPHOS

153 Although mutants with a single SBS bound Spg1 and inhibited GTP dissociation, the equil

154 than the corresponding mutants with a single SBS, multiple SBSs probably interact to cause the high a

155 We named this site surface-binding site (SBS) A1.

156 to a region containing a Smad binding site (SBS) and a medea box.

157 s mRNAs that harbor a Staufen1-binding site (SBS) in their 3' untranslated regions (UTRs).

158 grades mRNAs harboring a STAU1-binding site (SBS) in their 3'-untranslated regions (3' UTRs).

159 ate association testing or the site-by-site (SBS) testing may underutilize the longitudinal feature o

160 16-binding site and four Spg1-binding sites (SBS), designated SBS1-SBS4.

161 ) binding to clustered Su(Hw) binding sites (SBSs) and recruitment of the insulator proteins Centroso

162 enome-wide analysis of Su(Hw)-binding sites (SBSs) in the ovary, showing that tissue-specific binding

163 an homomers with single-chain binding sites (SBSs) or monomers.

164 han demonstrated previously using an in situ SBS readout.

165 separation which creates a slightly smoother SBS.

166 ers, with an adapted solution blow spinning (SBS) device for intercalated placement of aligned reinfo

167 s study employed the solution blow spinning (SBS) technique for the rapid production of smart nanofib

168 The dip-spinning-SBS technology generates constructs with native mechanic

169 ng was compared through shear bond strength (SBS) studies with 2 different systems (etch-and-rinse an

170 tems that can maintain shear bond strengths (SBS) suitable for clinical performance are unable to lim

171 combination of the single-base substitution (SBS) "signatures" observed in germline, soma, and tumors

172 he reduced rate of single-base substitution (SBS) mutations in gene bodies and H3K4me1-rich regions.

173 ciated, mutational single-base substitution (SBS) signature in nonmalignant mammary cells or patient-

174 es for various DNA single base substitution (SBS) signatures and their associations with different ca

175 The single-base substitution (SBS) signatures of all CS BE cells analyzed were indisti

176 ational signatures single-base substitution (SBS)2 and SBS13 were present in 88% and 91% of cases, re

177 Single base substitutions (SBSs) and insertions/deletions are critical for generati

178 54 signatures for single base substitutions (SBSs), 11 for doublet base substitutions (DBSs) and 16 f

179 ) laser on the corneal stromal bed surfaces (SBS).

180 Scleral buckle surgery (SBS) is a surgical option in stage 4 ROP, though anatomi

181 ings in a patient with Shaken baby syndrome (SBS).

182 dications for HPN were short bowel syndrome (SBS) (59%), PNDD (14%), congenital enteropathies (10%),

183 t for the treatment of short bowel syndrome (SBS) and potentially other intestinal diseases (e.g., IB

184 vances in the areas of short bowel syndrome (SBS) and small bowel transplantation (SBT).

185 evelopment program for short bowel syndrome (SBS) are reviewed.

186 posed in patients with short-bowel syndrome (SBS) as a rehabilitative therapy, but its effects on abs

187 nal failure (CIF) with short bowel syndrome (SBS) as the leading cause.

188 Short bowel syndrome (SBS) can lead to intestinal failure and require total or

189 Patients with short bowel syndrome (SBS) dependent on home parenteral nutrition (HPN) common

190 testinal adaptation in short bowel syndrome (SBS) includes morphologic processes and functional mecha

191 Short bowel syndrome (SBS) is a rare disease that results from extensive resec

192 Short bowel syndrome (SBS) is a serious malabsorption disorder, and dietetic m

193 Short bowel syndrome (SBS) is associated with diminished levels of serum fats

194 ediatric patients with short bowel syndrome (SBS) is now possible because of parenteral nutrition and

195 Short bowel syndrome (SBS) leads to severe morbidity and mortality.

196 Short bowel syndrome (SBS) may induce a plethora of clinical symptoms ranging

197 ain in an experimental short bowel syndrome (SBS) model in piglets.

198 cohort of nonmalignant short bowel syndrome (SBS) patients.

199 tcome of neonates with short bowel syndrome (SBS) who require parenteral nutrition (PN).

200 SRSB) in patients with short bowel syndrome (SBS) who were "permanently" dependent on parenteral nutr

201 olume in patients with short bowel syndrome (SBS) with intestinal failure, increasing intestinal wet

202 ation in children with short bowel syndrome (SBS).

203 urred by patients with short-bowel syndrome (SBS).

204 s exist in humans with short-bowel syndrome (SBS).

205 ption in patients with short bowel syndrome (SBS).

206 intestinal failure is short bowel syndrome (SBS).

207 ation in children with short bowel syndrome (SBS).

208 managing patients with short bowel syndrome (SBS).

209 Sick-building syndrome (SBS) is an increasingly common problem.

210 ms (often denoted as sick building syndrome (SBS)), chronic respiratory symptoms, and respiratory inf

211 impacts, known as "sick building syndrome" (SBS).

212 bacteriophage using sequencing by synthesis (SBS) as a paradigm.

213 te a version of the Sequencing by Synthesis (SBS) chemistry that potentially can become a preferred t

214 DNA sequencing by synthesis (SBS) offers a robust platform to decipher nucleic acid s

215 DNA sequencing by synthesis (SBS) offers an approach for potential high-throughput se

216 port four-color DNA sequencing by synthesis (SBS) on a chip, using four photocleavable fluorescent nu

217 DNA sequencing by synthesis (SBS) on a solid surface during polymerase reaction can d

218 DNA sequencing by synthesis (SBS) on a solid surface during polymerase reaction offer

219 d with in situ cDNA sequencing by synthesis (SBS) to identify 80,408 single guide RNAs (sgRNAs) in 10

220 DNA sequencing by synthesis (SBS) using reversible fluorescent nucleotide terminators

221 DNA sequencing-by-synthesis (SBS) technology, using a polymerase or ligase enzyme as

222 by using Illumina's sequencing-by-synthesis (SBS) technology, which allowed us to characterize the co

223 hnologies, based on sequencing-by-synthesis (SBS), are starting to deliver large amounts of DNA seque

224 E) and the Illumina sequencing-by-synthesis (SBS-DGE) sequencing platforms.

225 to use the solution blow spinning technique (SBS) to rapidly produce colorimetric nonwoven indicators

226 atory arthritis (chondrocalcinosis) and that SBS patients may be prone to develop extreme hypomagnesa

227 e in rapidly dividing cells, suggesting that SBS signature 1 is driven by rounds of DNA replication o

228 The SBS suppression results from an effective broadening of

229 The side cuts were straight, and the SBS appeared smoother in cuts obtained using 150 kHz.

230 Comparisons between PGS and the SBS testing revealed that PGS provided smaller phenotype

231 Both the SBS and medea box are necessary for complex formation an

232 nsequently, smart nanofibers produced by the SBS technique, using PCL and anthocyanins from agro-indu

233 nificantly higher than predicted TEE for the SBS group (1875 +/- 276 compared with 1517 +/- 175 kcal/

234 Measured TEE was significantly lower in the SBS group than in the non-SBS group (P < 0.01); however,

235 of the polymerase reaction and increases the SBS efficiency.

236 Among the residues lining the SBS-A1 site, two (Gln(700) and Tyr(717)) promoted altern

237 The quality and smoothness of the SBS post-FS laser dissection were graded for statistics.

238 The average values of the SBS quality of the anterior lamellar cut were found to b

239 veral surgical options for management of the SBS, including construction of intestinal valves or reve

240 te estimates and higher sensitivity than the SBS testing with comparable specificities.

241 enotype-related biological pathways than the SBS testing.

242 We propose that the SBS-A1 site is unique to alternansucrase and appears to

243 Produced via the SBS method, these indicators were characterized aiming t

244 mcision, pregnancy) were integrated with the SBS, generating a RI for each HESN.

245 -act sex in the UK, had major impacts on the SBSs and RIs of each cohort.

246 ithstanding the substantial success of these SBS platforms, challenges continue to limit the ability

247 Optimization of the steps involved in this SBS approach will further increase the read-length.

248 ore UPF1 and ~two- to fivefold more of those SBS-containing mRNAs that were tested, and it comparably

249 onators are achieved to overcome barriers to SBS in the visible, including 1 dB/meter waveguide losse

250 eral multilayered retinal hemorrhages due to SBS.

251 Patients were matched to SBS controls with the same digestive characteristics.

252 Remarkably, SlmA binding to SBSs dramatically enhanced its ability to interfere with

253 dietary manipulations could be used to treat SBS.

254 turn out to be ubiquitous across cell types: SBS signature 1, which consists primarily of transitions

255 h macronutrients, micronutrients, and water, SBS results in intestinal failure (IF).

256 ed ultra-narrow linewidth visible wavelength SBS lasers opens the door to compact quantum and atomic

257 qualitatively different from monomers, while SBS homomers are much less distinct, supporting the hypo

258 TEE was measured in 22 participants, 11 with SBS and 11 sex-, age-, and body mass index (BMI)-matched

259 ime HPN was feasible and safe in adults with SBS and, compared with overnight HPN, improved subjectiv

260 y of daytime infusions of HPN in adults with SBS without diabetes.

261 iderable amounts of alcohols associated with SBS.

262 The management goal for children with SBS is to promote intestinal adaptation while preserving

263 Thirty-two children with SBS on PN were included.

264 e total charges incurred by 41 children with SBS over the past decade, encompassing both inpatient an

265 intestinal absorption rate in children with SBS, focusing on the role of the remnant colon.

266 organ transplantation rates in children with SBS.

267 roviders and families who have children with SBS.

268 he colon as a salvage organ in children with SBS.

269 rom a contemporary cohort of 49 infants with SBS and cholestasis whose PN course included soybean ILE

270 l of a fish oil-based ILE in 42 infants with SBS who developed cholestasis (serum direct bilirubin >2

271 the management of a 60 year old patient with SBS and recurrent joint attacks was for different medica

272 The patient with SBS presented with a body mass index of 16.5 kg/m2 after

273 A minority of patients with SBS and inflammatory bowel diseases had colon-in-continu

274 0.5% [n = 2/19]), whereas most patients with SBS and vascular or other diseases had colon-in-continui

275 al energy expenditure (TEE) in patients with SBS by using the doubly labeled water (DLW) method to in

276 In assessment of patients with SBS complaints, specific building-related illnesses sugg

277 er, and dietetic management of patients with SBS is extremely challenging.

278 small bowel transplantation in patients with SBS permanently dependent on PN.

279 ndomized, controlled trials in patients with SBS support the safety and efficacy of teduglutide as an

280 Measured TEE in patients with SBS was significantly higher than predicted by using sta

281 transplant surgical option for patients with SBS who require long-term PN.

282 Patients with SBS who suffer from IF require parenteral nutrition for

283 , double-blind, phase 3 trial, patients with SBS with intestinal failure requiring PS >=3 d/wk were r

284 Glepaglutide treatment in patients with SBS with intestinal failure resulted in clinically relev

285 We collected data from 85 patients with SBS with intestinal failure, according to the European S

286 renteral support (PS) needs in patients with SBS with intestinal failure.

287 stimate energy requirements of patients with SBS, and revision is needed to prevent underfeeding and

288 the effects of teduglutide on patients with SBS, we associated reduced parenteral support volume wit

289 Nearly half of patients with SBS-CIF on PS are aged 65 y or older, with PS dependence

290 el modifications at imaging in patients with SBS-CIF receiving TED and to assess their predictive val

291 retrospective study including patients with SBS-CIF treated with TED from 2009 to 2018 with availabl

292 Teduglutide in treating patients with SBS-IF meets the traditional cost-effectiveness criteria

293 e performed a 24-week study of patients with SBS-IF who were given subcutaneous teduglutide (0.05 mg/

294 as generally well tolerated in patients with SBS-IF.

295 reduces parenteral support in patients with SBS-IF.

296 best supportive care alone in patients with SBS-IF.

297 testinal tissue specimens from patients with SBS.

298 (IFALD), a major morbidity in patients with SBS.

299 stive capacity in parenterally fed rats with SBS.

300 transporter PepT1 in adults with or without SBS.