ライフサイエンスコーパス: SFT

1 SFT (stimulator of Fe transport) is a novel transport pr

2 SFT and SP influenced cotton domestication and are ideal

3 SFT expression did not enhance levels of HeLa cell surfa

4 SFT expression was not affected by iron.

5 SFT has six predicted transmembranous domains and a func

6 SFT is the first component of the mammalian Fe membrane

7 SFT promises to advance the goal of full automation in i

8 SFT would be acceptable for use in larger studies.

9 SFT-mediated transport has properties defined for transf

10 as confirmed in tumor biopsies from 29 of 38 SFT patients (76%) in an independent cohort.

11 The 1-SST, 1-FFT and 6-SFT genes had correlated expression patterns in our whea

12 nd sucrose:fructan 6-fructosyltransferase (6-SFT) were clustered together with multiple copies of vac

13 geted RPT as a viable treatment for advanced SFT.

14 ncluding LA, flower with fewer leaves via an SFT-dependent pathway, suggesting that miR319-sensitive

15 isplacement plethysmography body density and SFT methods showed positive (overestimating) constant bi

16 splacement plethysmography body density, and SFT ranging from a mean +/- SD of 29.5 +/- 13.2 kg via 4

17 The gene expression of DMT1, HFE, and SFT did not fully correlate with the functional response

18 lated with gene expression of DMT1, HFE, and SFT in an experimental model of human absorptive enteroc

19 amined and gene expression of DMT1, HFE, and SFT was measured.

20 Conclusion: FAPalpha is highly expressed by SFT and may serve as a target for imaging and therapy.

21 demonstrate that iron transport mediated by SFT is itself an iron-dependent process.

22 Transport mediated by SFT was inhibitable by diethylenetriaminepentaacetic aci

23 nvolved in cellular iron assimilation called SFT or Stimulator of Fe Transport.

24 When stably expressed in HeLa cells, SFT was found to stimulate the uptake of both transferri

25 TER program of the German Cancer Consortium, SFT (n = 34) had the highest median FAPalpha messenger R

26 is patients therefore suggests that enhanced SFT expression contributes to the etiology of this iron

27 th control cells and cells stably expressing SFT displayed reduced Fe uptake as well; levels of trans

28 rin-bound Fe by HeLa cells stably expressing SFT was time- and temperature-dependent; both the rate a

29 ide linear range, from 4.0 pM to 490 muM for SFT and 4.0 pM to 520 muM for SFM, with picomolar detect

30 antification limits (0.53 pM and 1.75 pM for SFT, 0.41 pM and 1.35 pM for SFM, respectively).

31 at a ferrireductase activity is required for SFT function in Fe3+ transport and that Cu depletion red

32 nd protein expression in biopsy samples from SFT patients using immunohistochemistry and multiplexed

33 Higher SFT performance resulted in greater recruitment of right

34 f these agents in angiosarcoma, EHE, and HPC/SFT are poorly understood.

35 ally low, several angiosarcoma, EHE, and HPC/SFT patients demonstrated response or durable disease st

36 ain patients with angiosarcoma, EHE, and HPC/SFT, but more studies are needed to confirm these findin

37 d as a potentially promising regimen for HPC/SFT.

38 rials will not only improve treatment of HPC/SFT but will also lead to a new paradigm of personalized

39 olecular pathogenesis and aberrations of HPC/SFT is needed to determine optimal therapeutic agents.

40 to the relatively insensitive nature of HPC/SFT to radiotherapy and cytotoxic chemotherapy, new ther

41 al features, diagnosis, and treatment of HPC/SFT.

42 mangiopericytoma/solitary fibrous tumor (HPC/SFT) spectrum of tumors, focusing on the histopathologic

43 mangiopericytoma/solitary fibrous tumor (HPC/SFT).

44 sis of multicolor, tissue-microarray images, SFT correctly found the overlap of markers with known su

45 ntracellular iron by desferrioxamine impairs SFT transport and iron-binding functions.

46 NAB2-STAT6 fusion proteins was confirmed in SFT, and the predicted fusion products harbor the early

47 ted cells suggests a critical role for Cu in SFT function.

48 ncreasing GA concentrations and inactivating SFT in the leaves and AP1/MC at the shoot apex.

49 e-binding studies reveal that the ability of SFT to bind and mediate transport of extracellular iron

50 To test this hypothesis, the ability of SFT to directly mediate Fe2+ import was examined.

51 APalpha-directed theranostics in the care of SFT patients.

52 or Fe uptake was unaffected by expression of SFT (5.6 versus 5.1 microM measured for control), the Vm

53 Although expression of SFT enhanced Fe2+ uptake by HeLa cells, Cu depletion did

54 The failure of SFT expression to stimulate Fe uptake above basal levels

55 r characterize the structure and function of SFT, we studied this human factor in rodent BHK cells.

56 and flower development via the induction of SFT both before and after floral transition, and their e

57 slation inhibitory element and inhibition of SFT expression in Xenopus oocytes was found to be reliev

58 the iron chelator desferrioxamine, levels of SFT mRNA increase in an actinomycin D-sensitive manner.

59 AB2-STAT6 as the defining driver mutation of SFT and provide an example of how neoplasia can be initi

60 The 3' untranslated region of SFT contains a translation inhibitory element and inhibi

61 Thus, homeostatic regulation of SFT expression not only ensures that sufficient levels o

62 n content and increases the transcription of SFT.

63 y barriers' heights and the channel width of SFT can be substantially modulated, resulting in tunable

64 ated the effects of Cu (copper) depletion on SFT function.

65 account for the influence of Cu depletion on SFT-mediated Fe uptake.

66 ort the concept that classic pleuropulmonary SFT and deep-seated HPC are separate entities that share

67 ffered to eligible patients with progressive SFT.

68 exposed to high levels of iron down-regulate SFT expression in a time-dependent and reversible fashio

69 tif may play an important role in regulating SFT activity through interaction with intracellular iron

70 Based on the relationships, SFT identifies segments belonging to background regions;

71 with the corresponding aligned PAR1 residues SFT 220-222.

72 the simultaneous detection of sulfathiazole (SFT) and sulfamethoxazole (SFM) residues in honey, beef,

73 loop 5 antibodies recognize and bind surface SFT.

74 Naming Test (BNT) and Semantic Fluency Test (SFT), neuropsychological measures of semantic retrieval,

75 ion Test (COWAT), and Semantic Fluency Test (SFT).

76 Both vacancy-type stacking fault tetrahedra (SFT) and interstitial loops coexist in the same region,

77 Previous studies demonstrated that SFT (Stimulator of Fe Transport) facilitates both transf

78 y and immunofluorescence data and found that SFT performed well over multiple, diverse image characte

79 The observation that SFT oligomerizes, along with other structural and mechan

80 The unexpected observation that SFT transcript levels are up-regulated in hemochromatosi

81 Kyte-Doolittle analysis suggests that SFT has six transmembrane-spanning segments.

82 roblast, and smooth muscle cell types of the SFT.

83 ities from rational symplectic field theory (SFT).

84 t area (AFA) and subcutaneous fat thickness (SFT) were measured using T1-weighted axial slices at the

85 nt fat mass estimated by skinfold thickness (SFT) measurements at 4 body sites at 3-5 d, 6 wk, and 4

86 e data, called Segment and Fit Thresholding (SFT).

87 A stimulator of Fe transport (SFT) was identified by functional expression cloning in

88 MT1), HFE, and stimulator of iron transport (SFT) are transmembrane proteins that have been implicate

89 le of the florigen gene SINGLE FLOWER TRUSS (SFT) and two mutations affecting a bZIP transcription fa

90 n factors by activating SINGLE FLOWER TRUSS (SFT) in the leaves and the MADS-Box gene APETALA1(AP1)/M

91 florigen-encoding gene SINGLE FLOWER TRUSS (SFT) in the leaves.

92 w the FLOWERING LOCUS T/SINGLE FLOWER TRUSS (SFT)-like and TERMINAL FLOWER1/SELF-PRUNING (SP)-like ge

93 ttern of FAPalpha in solitary fibrous tumor (SFT) and its potential use as a radiotheranostic target.

94 h a highly malignant solitary fibrous tumor (SFT) enrolled in our clinical sequencing program called

95 Solitary fibrous tumor (SFT) is a rare soft-tissue sarcoma with limited treatmen

96 woman with recurrent solitary fibrous tumor (SFT)/hemangiopericytoma was enrolled in a clinical seque

97 nitiating events in solitary fibrous tumors (SFT).

98 kg via 4-compartment to 39.1 +/- 11.7 kg via SFT.

99 her protein terminus does not interfere with SFT function in nontransferrin-bound iron uptake.