ライフサイエンスコーパス: SHED

1 SHED are not only derived from a very accessible tissue

2 SHED were identified to be a population of highly prolif

3 SHEDs were treated with P(i).

4 , SCAP (stem cells from apical papilla), and SHED (stem cells from human-exfoliated deciduous teeth)

5 ) as a specific interacting partner for both SHED and transmembrane HEMO proteins.

6 bilized SHED group compared with the control SHED.

7 termed here the split helical dimerization (SHED) region.

8 cleft is occluded, and its newly identified SHED region may promote an unexpected dimerization mode.

9 ) treatment is able to significantly improve SHED-mediated osteogenic differentiation and immunomodul

10 eatment is a practical approach to improving SHED-based cell therapy.

11 but inhibited adipogenic differentiation in SHED.

12 Mechanistically, SHED transplantation induces activated T-cell apoptosis

13 buted to both endothelial differentiation of SHED and recruitment of host blood vessels.

14 ylation and inhibited the differentiation of SHED into endothelial cells.

15 that regulate endothelial differentiation of SHED.

16 Exposure of SHED to EGM2-MV supplemented with VEGF induced potent ac

17 a-catenin cascade, leading to improvement of SHED-mediated bone regeneration, and also upregulates TE

18 RT/FASL signaling, leading to improvement of SHED-mediated T-cell apoptosis and ameliorating disease

19 lpha stabilization enhances cell survival of SHED through modulating various target genes and potenti

20 ere we show that systemic transplantation of SHED via the tail vein ameliorates ovariectomy (OVX)-ind

21 ed structural similarities between the PEAK1 SHED region and the C-terminal extension of the Parkinso

22 carbonate-substituted mineral and with SCAP, SHED, and GF cells creating a less crystalline material

23 In vivo, VEGFR1-silenced SHED seeded in tooth slice/ scaffolds and transplanted i

24 secreted from the cell surface as a soluble SHED form which can be detected in pregnant women blood.

25 ough RNA sequencing in HIF-1alpha-stabilized SHED and demonstrated its essential role in HK2 and Glut

26 n were detected in the HIF-1alpha-stabilized SHED group compared with the control SHED.

27 aspase 3 expression in HIF-1alpha-stabilized SHED in hypoxic conditions.

28 HIF-1alpha-stabilized SHED were encapsulated in PuraMatrix hydrogel, injected

29 In summary, SHED-mediated T-cell apoptosis via a FasL/Fas pathway re

30 cells from human exfoliated deciduous teeth (SHED) are a unique postnatal stem cell population, posse

31 Stem cells from exfoliated deciduous teeth (SHED) exposed to endothelial growth medium (EGM-2MV) sup

32 cells from human exfoliated deciduous teeth (SHED) for evaluation of gene/protein function, WNT signa

33 Stem cells from exfoliated deciduous teeth (SHED) possess multipotent differentiation and immunomodu

34 cells from human exfoliated deciduous teeth (SHED) were preconditioned to a hypoxic condition by hypo

35 stem cells from exfoliated deciduous teeth (SHED), periodontal ligament stem cells (PDLSCs), stem ce

36 lated from human exfoliated deciduous teeth (SHED).

37 cells from human exfoliated deciduous teeth (SHED)].

38 tabilized by one pseudokinase domain and the SHED domain of the PEAK3 dimer.

39 This SHED-mediated immunomodulation rescues OVX-induced impai

40 After in vivo transplantation, SHED were found to be able to induce bone formation, gen

41 However, the mechanism by which SHED treat immune diseases is not fully understood.