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1 SP alone blocks HIV transcription in the absence of ART
2 SP and IL-1beta levels were assayed in the culture mediu
3 SP and NK-A are derived from the Tac1 gene that is alter
4 SP potently promoted VEC activation in vitro and blockad
5 SP treatment rapidly degrades a host transcription facto
6 SP-D was not active on LPAIV but was on H3 HAs.
7 SPs coordinated with d-chirality demonstrate greater tha
8 SPs possess functional domains (SAND, PHD, bromodomain)
10 energy expenditure (IM: 4,939 kcal day(-1); SP-17: 6,461 kcal day(-1), p = 0.004); differences relat
19 otide (FAD) to inhibit demethylase activity, SP-2509 has previously been shown to inhibit LSD1 protei
22 rmore, when inferring sub-European ancestry, SP clearly showed bias, unlike the proposed approaches.
25 ated Gag proteins comprising the MA, CA, and SP domains (MACASP) or the MA and CA domains (MACA) indu
26 e interactions between CQA dehydrodimers and SP (gPRPs, aPRPs, statherins/P-B peptide, and cystatins)
27 s' (TYGRESS) that is a hybrid of cryo-ET and SP-cryo-EM, and is able to achieve close-to-nanometer re
31 c, and functional characterization of SP and SP-derived EVs from uninfected and HIV-infected men.
33 hange chromatography where STREAMLINE SP and SP-XL high density adsorbents were selected as the adsor
39 ysterious but requires surfactant protein B (SP-B), which is synthesized as a precursor (pre-proSP-B)
45 gravir concentrations were quantified in BP, SP, CVF and rectal tissue (RT) at 24 hours postdose (C24
46 criptional regulation and XPB degradation by SP strengthens the potential of HIV transcriptional inhi
48 e proposed cardiac progenitor cells, cardiac SP cells fuse with preexisting cardiomyocytes to stimula
50 mGC(SS)) and Streptococcus pneumoniae (ComGC(SP)), revealing that this pilin displays extensive struc
51 sue cultures we found that spines containing SP survived considerably longer than spines of equal siz
54 Glaucoma suspect eyes with higher corneal SPs and lower CCT, suggestive of thin and stiff corneas,
55 nding lectin (MBL) and surfactant protein D (SP-D) are regulated by tissue fibroblasts at extravascul
62 head region high-mannose glycosites dictates SP-D activity, the ability to predict these glycosite gl
63 al small SPs, proximal large SPs, and distal SPs were 4.7 (95% CI, 4.0-5.6), 14.8 (95% CI, 9.0-24.3),
64 nomas 4.0; 95% CI, 3.0-5.5 and HR for distal SPs with synchronous adenomas 2.4; 95% CI, 1.7-3.4).
65 ct with HLA-DR-derived self-peptides (HLA-DR-SPs), peptides from MS-associated foreign agents (Epstei
66 cited by electrical stimulation or exogenous SP, were recorded in the presence or absence of fluoroci
69 arkable stress tolerance and intense flavor, SP has been used as an important germplasm donor in mode
72 These studies suggest a novel mechanism for SP-A in asthma as a modulator of IL-13-induced inflammat
75 lowed conditional two-stage decay functions, SP-negative (SP-) spines and all spines of SP-deficient
83 for stem cells throughout the body; however, SP cells isolated from the heart have been studied exclu
84 apidly rebounds when XPB reemerges; however, SP alone without ART maintains the transcriptional suppr
85 gate the activities of two recombinant human SP-D forms against representative LPAIV strains, includi
86 rred in the ROP patients who showed impaired SP at baseline only if rsfMRI diagnosis status shifted t
90 tivity of IL-13 is dramatically augmented in SP-A(-/-) mice, which have significantly increased neutr
92 rotein-unbound bictegravir concentrations in SP, RT, and CVF highly exceeded the EC50 value (1.1 ng/m
93 e median total bictegravir concentrations in SP, RT, and CVF were 65.5 (20.1-923) ng/mL, 74.1 (6.0-47
95 th animal models sufficient and deficient in SP-A challenged with IL-13 and primary epithelial cells
98 e important and abundant class of factors in SP is extracellular vesicles (EVs), which, in general, a
99 results show that a significant increase in SP levels promotes Treg dysfunction in DED, and blockade
108 as of active synovitis/IFP fibrosis inducing SP degradation, resulting in a cell-based product altern
111 energy of metallacyclobutane intermediates (SP/TBP isomers), whereas aryloxides with pendant ortho a
112 elivering murine or human proSFTPB cDNA into SP-B deficient mice restores surfactant homeostasis, pre
113 HIV infection in vitro Here we investigated SP as a possible block-and-lock agent for a functional c
116 ng effect) of RBF, health promotion and IPTp-SP strategies was greatest in 17.7% (17/96) of high burd
123 al model, we investigated the effect of IPTp-SP doses and timing, after 17 weeks of gestation, on the
125 The effectiveness in birth weight of IPTp-SP is compromised by A581G-bearing parasites, but there
133 A581G has been associated with reduced IPTp-SP efficacy and enhanced morbidity in SP recipients.
134 lower in the IPTp-MQ group than in the IPTp-SP group, and within the IPTp-MQ group it was lower at d
136 rtemisinin-piperaquine (IPTp-DP) versus IPTp-SP to prevent clinical malaria infection (and its sequel
137 treatment in the first trimester, when IPTp-SP is contraindicated, could substantially improve pregn
138 sting and treatment at first visit with IPTp-SP may offer benefit, especially in areas with high-grad
143 no polyp, proximal small SPs, proximal large SPs, and distal SPs were 4.7 (95% CI, 4.0-5.6), 14.8 (95
144 ased in individuals with proximal SPs (large SPs in particular) 3 years or more after the colonoscopy
147 by 0.72 mum/year relative to eyes with lower SP-A1 and thicker CCT (95% confidence interval [CI], 0.1
153 t, single-particle cryo-electron microscopy (SP-cryo-EM) routinely reaches near-atomic resolution of
154 onal two-stage decay functions, SP-negative (SP-) spines and all spines of SP-deficient animals showe
157 rst negative screening, approximately 50% of SP mutation carriers develop HCM over 15 years of follow
160 signaling with spantide I, an antagonist of SP receptor Neurokinin-1, significantly reduced corneal
162 tes Treg dysfunction in DED, and blockade of SP effectively restores Treg function and suppresses DED
163 oted VEC activation in vitro and blockade of SP signaling with spantide I, an antagonist of SP recept
164 riptomic, and functional characterization of SP and SP-derived EVs from uninfected and HIV-infected m
165 , long-term treatment with concentrations of SP that potently degrade XPB does not lead to global dys
166 ies set out to determine the contribution of SP-A to the response of a key effector cytokine in asthm
168 l peptides derived from the lectin domain of SP-A2 that contain the major allelic variant (223Q) main
172 Indeed, using 2-photon time-lapse imaging of SP-transgenic granule cells in mouse organotypic tissue
176 by our group showed differences in levels of SP-A binding to non-live mycoplasma membrane fractions t
177 nzyme implicated in plasticity mechanisms of SP MSNs, which are known to regulate feeding and disturb
179 cultures of normal Tregs in the presence of SP led to a significant reduction in both Treg frequenci
180 F-actin, we speculated that the presence of SP within large spines could explain their long lifetime
186 , SP-negative (SP-) spines and all spines of SP-deficient animals showed single-phase exponential dec
188 his disease, as de novo protein synthesis of SP-B in alveolar type 2 epithelial cells is required for
189 domain (CTLD2) is critical for the uptake of SP-D, but not MBL, indicating an additional level of com
196 factors, such as neuropeptides, substance P (SP), and neurokinin A (NK-A), which mediate hematopoieti
202 etrospective analysis of adult and pediatric SP mutation carriers identified during family screening
204 epeatability of full-field static perimetry (SP) and between-eye symmetry of kinetic perimetry (KP) w
206 -scale AnMBRs were operated in single-phase (SP) and two-phase (TP) mode across incremental increases
207 larimetric compressed ultrafast photography (SP-CUP) to record light-speed high-dimensional events in
209 sessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, rad
210 es/mL) in blood plasma (BP), seminal plasma (SP), rectal fluid (RF), and cervicovaginal fluid (CVF) a
212 HIV transmission.IMPORTANCE Seminal plasma (SP), the major vehicle for HIV, can modulate HIV transmi
213 ceeded to develop COVID-19 severe pneumonia (SP) and DHF had significantly higher levels of IL-6, IL-
214 ak imaging with stereoscopy and polarimetry, SP-CUP enables video-recording of five photon tags (x, y
217 ed by evaluating FACS-based side population (SP), autofluorescence (AF+) and Alde-red assays for CSCs
219 arbored a reduced number of single-positive (SP) CD8(+) thymocytes without any defects in the SP CD4(
222 ally, we investigated if sensory processing (SP) change during CCT is associated with individual psyc
224 omyopathy (HCM) caused by sarcomere protein (SP) gene mutations is current standard of care, but ther
228 antibodies against the structural proteins (SP) of the capsid can be used to monitor seroconversion
229 increased the risk for CRC (HR for proximal SPs with synchronous adenomas 4.0; 95% CI, 3.0-5.5 and H
231 the first colonoscopy (HR for small proximal SPs 2.6; 95% CI, 1.7-3.9 and HR for large proximal SPs 8
232 t CRC increased in individuals with proximal SPs (large SPs in particular) 3 years or more after the
233 ecular markers of sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) resistance did not increase mar
235 mpared with IPTp-sulphadoxine-pyrimethamine (SP) in human immunodeficiency virus (HIV)-uninfected and
236 ipients, relative to women who last received SP > 4 weeks before delivery, recent SP receipt was asso
237 eceived SP > 4 weeks before delivery, recent SP receipt was associated with lower birth weight in wom
239 reatment response neuromarkers based on rsFC-SP change and pave the road to more personalized interve
241 iously been associated with STAT6 signaling, SP-A inhibited IL-13-induced STAT3 phosphorylation in mi
245 or individuals with no polyp, proximal small SPs, proximal large SPs, and distal SPs were 4.7 (95% CI
246 y composition, between the all-male Spear17 (SP-17) and all-female Ice Maiden (IM) transantarctic exp
249 ity (SE = 87.88%) and increased specificity (SP = 92.31%) of control-patient group differences when c
250 tests such as sensitivity (SN), specificity (SP), positive and negative predictive values were perfor
254 ajor regulator of long-term spine stability: SP clusters stabilize spines, and the presence of SP ind
255 ion exchange chromatography where STREAMLINE SP and SP-XL high density adsorbents were selected as th
256 cted striatonigral (SN) and striatopallidal (SP) medium spiny neurons (MSNs) as playing a key role.
258 of large spines also contains synaptopodin (SP), an actin-modulating and plasticity-related protein.
261 uction of transient synaptic potentiation (t-SP) at glutamatergic synapses in the nucleus accumbens c
262 total gastric meal retention between (99m)Tc-SP and (99m)Tc-SC, was found to be comparable at all mea
264 nts were randomly assigned to either (99m)Tc-SP or (99m)Tc-SC on the first GES session before crossed
265 clear if the (99m)Tc-sodium phytate ((99m)Tc-SP) is as reliable as the gold-standard (99m)Tc-sulfur c
268 n the head region, our data demonstrate that SP-D may not protect against virus containing these HA s
275 es and non-cardiomyocytes, identified by the SP phenotype, contribute to endogenous cardiac regenerat
277 cal and parasitological response rate of the SP + AQ regimen in children with asymptomatic malaria wa
281 of Salmonella-spiked blood samples with the SP-PCR resulted in a limit of detection (LoD) as low as
285 ry, this study showed how HMGB1 is linked to SP and NK-A to protect the most primitive hematopoietic
288 s/polyps (SSA/Ps) (n = 70; 66%), unspecified SPs (n = 3, 3%), and false positive SPs (n = 5, 5%).
290 result in epigenetic suppression of HIV upon SP treatment interruption, since virus rapidly rebounds
291 ry neurons directly promote angiogenesis via SP signaling in response to inflammation in the cornea.
292 TANCE Treatment of HSV-1-infected cells with SP-2509 blocked viral DNA replication, gene expression a
293 igh-mannose glycans and do not interact with SP-D, and that sequence analysis can predict glycan subt
294 participating in a trial comparing IPTp with SP against intermittent screening by rapid diagnostic te
295 gnificantly higher in COVID-19 patients with SP, patients with DHF had 25-fold higher levels, whereas
297 Unfortunately, long-term pre-treatment with SP does not result in epigenetic suppression of HIV upon