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1 SR Ca(2+) content increases during compensated hypertrop
2 SR Ca(2+)-content was unchanged in POAF despite greater
3 SR proteins are essential splicing regulators mostly con
4 SR rate after 24 months was 0% in the Kono group versus
5 SR was defined as modified thrombolysis in cerebral isch
6 SR-717 also induced the expression of clinically relevan
7 SR-717 displayed antitumor activity; promoted the activa
8 SR-B1 is required for Mtb binding to and translocation a
9 SR-B1 is up-regulated in prostate cancer tissue, suggest
10 SR-FTIR and FPA-FTIR measurements were performed in live
11 SRs can bind to a range of ligands and enhance the elimi
12 DE225 via scavenger receptor class B type 1 (SR-B1) and CD15 on brain SHH MB cells in vitro, ex vivo,
18 of [Au(25)SR(19)](0), leading back to [Au(25)SR(18)](-) and eliminating precisely one surface ligand.
19 We find that oxidative etching of [Au(25)SR(18)](-) nanoclusters adds an excess thiolate ligand a
20 on can be reversed by CO reduction of [Au(25)SR(19)](0), leading back to [Au(25)SR(18)](-) and elimin
25 s of single-RyR gating can profoundly affect SR Ca(2+) release even if open probability and mean OTs
30 Our study suggests that greater SD(ada) and SR increased g(m) by increasing S(mes) and creating addi
31 es using syngeneic SR-B1 WT (SR-B1(+/+)) and SR-B1 KO (SR-B1(-/-)) prostate cancer cells in WT and ap
34 genetically targeted fluorescent probe, and SR calcium content was assessed by measuring caffeine-st
36 omic and protein polymorphic sites to RR and SR was assessed using phylogenetic analysis and Bayesian
38 graphy parameters demonstrated LA strain and SRs to be independent prognosticators of ischemic stroke
41 ction of JNK2 in CaMKII-dependent arrhythmic SR Ca(2+) leak and a CaMKII-independent uptake exacerbat
46 high rating of A MeaSurement Tool to Assess SRs 2 were publication in a journal where Preferred Repo
48 On the basis of A MeaSurement Tool to Assess SRs 2, confidence in SRs results was classified as high,
50 In cells expressing the C674S mutant, basal SR calcium content was decreased by 31% and the H(2)O(2)
51 dox activation of SERCA C674 regulates basal SR calcium content, thereby mediating the pathologic rea
52 patients with clinical- and biomarker-based SR acute GVHD, sirolimus demonstrates similar overall in
55 d a platform for three-dimensional cryogenic SR and focused ion beam-milled block-face EM across enti
61 -refractory acute graft-versus-host disease (SR-aGVHD) poses one of the most vexing challenges faced
67 en SR Ca(2+) leak present, the JNK2-enhanced SR Ca(2+) uptake limited leak-induced reduction in SR Ca
69 ast 4 centuries reveals higher-than-expected SR variations over much of the history; only after 1940
72 SBP goals of <140 and < 160mmHg following SR with EVT appear to be associated with better clinical
73 n ATP-responsive ternary polyplexes core for SR-A siRNA and catalase complexation, and a phosphatidyl
74 s, we demonstrate a cell-autonomous role for SR in regulating synaptic NMDAR function at Schaffer col
75 These studies suggest a central role for SR-A complexes in epidermal lipid rafts in mediating the
77 ylserine-modified rHDL-based outer shell for SR-BI and CD36 targeting, in which pitavastatin is packa
78 arried out and Preferred Reporting Items for SRs and Meta-Analyses and rating by A MeaSurement Tool t
79 l reporting according to Preferred Items for SRs and Meta-Analyses should be mandatory for publicatio
80 journal where Preferred Reporting Items for SRs and Meta-Analyses was mandatory (OR [95% confidence
81 tudy, we applied synchrotron radiation-FTIR (SR-FTIR) microspectroscopy and focal plane array (FPA-FT
82 , and knockdown studies localized functional SR-As to FLOT-1-containing lipid rafts throughout the ep
84 ontent was unchanged in POAF despite greater SR Ca(2+)-leak, with a trend towards increased SR Ca(2+)
86 transfluthrin on Aedes aegypti explores how SR effects interact to impact the epidemiology of diseas
88 to both well-defined clusters and small Au(I)SR species was identified by ESI-MS and UV-vis spectrosc
90 ADRS scores did not change, but the mean IDS-SR score decreased from 38.8 (95% CI 31.2 to 46.5) to 35
92 ion of TDP-43 neuropathology by IkappaBalpha-SR, which is likely due to an induction of autophagy, wa
93 orm of the NF-kappaB inhibitor (IkappaBalpha-SR), which were then crossed with mice of both sexes, ex
94 arkably, neuronal expression of IkappaBalpha-SR transgene in mice expressing TDP-43(A315T) or TDP-43(
95 ependent kinase II)-dependent JNK2 action in SR Ca(2+) leak, JNK2-driven SERCA2 function was CaMKII i
99 n, using a single-neuron genetic approach in SR conditional KO mice from both sexes, we demonstrate a
100 n that was associated with a 50% decrease in SR calcium content, both of which were prevented by the
104 ockade in healthy myocytes that increases in SR Ca(2+) content and Ca(2+) transients can be driven by
105 present, mutations in six genes involved in SR calcium release have been identified as the genetic c
106 d to full-length RyR1, either purified or in SR membranes, strikingly different results were obtained
107 inate spontaneously without any reduction in SR [Ca(2+)], luminal regulation, Ca(2+)-dependent inacti
108 2+) uptake limited leak-induced reduction in SR Ca(2+), normalizing Ca(2+) transient amplitude, but a
109 ts demonstrate the critical role of REEP5 in SR/ER organization and function as well as normal heart
110 pletion in mouse cardiac myocytes results in SR/ER membrane destabilization and luminal vacuolization
111 rlobe distances when CaM is bound to RyR1 in SR membranes, purified RyR1, or a peptide corresponding
112 Surement Tool to Assess SRs 2, confidence in SRs results was classified as high, moderate, low, or ve
113 r other binding partners of TNPO3, including SR domain-containing splicing factors and tRNAs that ree
114 g showed that RyR2 dysfunction and increased SR Ca(2+)-uptake are sufficient to reproduce the Ca(2+)-
115 hanism has been suggested that the increased SR Ca2+ content and prolonged AP did not fully recover t
124 yngeneic SR-B1 WT (SR-B1(+/+)) and SR-B1 KO (SR-B1(-/-)) prostate cancer cells in WT and apolipoprote
125 bal longitudinal strain), LA strain rate (LA SR) at reservoir (LA longitudinal systolic strain rate),
126 nation of a single surface thiolate ligand (-SR) on gold nanoclusters can be realized, opening the do
129 ) transients amplitude and decay rate, lower SR Ca(2+) load and depressed cellular contractility) and
130 (SR Ca(2+)-ATPase), essential in maintaining SR Ca(2+) content cycling during each heartbeat, is comp
136 service areas but within the same region (ML-SR) and 1556 (1.9%) listed in different regions (ML-DR).
139 uction of various dialkylpolysulfides (RSS(n)SR) and other nitrogen-containing dialkylpolysulfide spe
140 s promise and ubiquitous presence in nature, SR has not been successively harnessed in engineering ap
142 ll-autonomous role for postsynaptic neuronal SR in regulating synaptic NMDAR function and suggests a
143 orylation of 2 proteins essential for normal SR-Ca(2+) cycling, the type-2 ryanodine receptor (RyR2)
144 K2-specific inhibition completely normalized SR Ca(2+) handling, attenuated arrhythmic Ca(2+) activit
146 ssion of urokinase (SR-uPA(+/0) mice) and of SR-uPA(+/0) bone marrow transplant recipients, and we us
148 owever, the high intensity and brightness of SR beams raise important issues regarding the potential
150 portantly, single-neuron genetic deletion of SR resulted in the elimination of LTP at 1 month of age,
151 ion, using single-neuron genetic deletion of SR, we establish a role of postsynaptic SR in regulating
152 ction to monitor and quantify the effects of SR X-rays on the stability of chrome yellows and related
155 t dendritic and postsynaptic localization of SR and d-serine by immunohistochemistry and electron mic
158 ver an extensive cross-regulatory network of SR proteins controlling their expression via alternative
159 Our results demonstrate the potential of SR for accelerating the data-driven design and discovery
161 Ca(2+) signals resulting from the release of SR Ca(2+) through RyR2s ("Ca(2+) sparks") and correspond
162 lication leverages the frequency response of SR, where the loss of resonance at out-of-band frequenci
164 the basis of our increased understanding of SR Ca(2+) leak as a shared Ca(2+)-dependent pathological
168 in the International Prospective Register of SRs and full reporting according to Preferred Items for
176 hosphorylation of SPEG and SERCA2a, prolongs SR re-uptake of calcium, and impairs cardiac function.
177 7, p = 0.03) versus placebo, as well as QIDS-SR scores in Stage 2 of SPCD (-2.5; Cohen's d Stages 1 a
178 ory of Depressive Symptomatology Scale (QIDS-SR), and subtests from the CogScreen and Cogstate cognit
183 of male children in a family, or sex ratio (SR), has a significantly smaller among-family variation
184 omatal densities (SD(ada) ), stomatal ratio (SR), mesophyll surface area exposed to IAS (S(mes) ) and
186 e show that mammalian SRP and SRP receptors (SR) are insufficient to generate the biologically requir
192 EP5 that is centrally involved in regulating SR/ER organization and cellular stress responses in card
201 ) signaling from the sarcoplasmic reticulum (SR) and the endoplasmic reticulum (ER) to mitochondria i
204 2 (RYR2), the major sarcoplasmic reticulum (SR) Ca(2+)-release channel in the heart, how RYR2 become
205 although spontaneous sarcoplasmic reticulum (SR) Ca(2+)-release events and L-type Ca(2+)-current alte
208 the skeletal muscle sarcoplasmic reticulum (SR) calcium release channel (ryanodine receptor, RyR1 is
211 is localized in the sarcoplasmic reticulum (SR) subdomain of triads where it forms large multimers.
212 e of Ca(2+) from the sarcoplasmic reticulum (SR) through RyR2 generates localized elevations of Ca(2+
213 ease Ca(2+) from the sarcoplasmic reticulum (SR) via a positive feedback mechanism in which fluxed Ca
214 i) diffuses into the sarcoplasmic reticulum (SR) where it is believed to form insoluble Ca(2+) salts,
215 e cell stored in the sarcoplasmic reticulum (SR), and another, with open RyRs and a depleted SR.
216 ium release from the sarcoplasmic reticulum (SR), the major calcium storage organelle in striated mus
220 re (SBP) after successful revascularization (SR) via endovascular therapy (EVT) is a known predictor
221 uality of dermatological systematic reviews (SRs) and identify factors that predict high methodologic
222 A significant number of systematic reviews (SRs) and meta-analyses (MAs) have evaluated the effect o
223 re searched for relevant systematic reviews (SRs) published in English from 15 December 2013 through
224 on an AFL substrate (AF+AFLs); sinus rhythm (SR) with an AFL substrate (SR+AFLs; control group).
225 We show that PEs in serine-arginine-rich (SR) proteins, a family of 14 essential SFs, are differen
226 al treatment of patients with standard risk (SR) acute GVHD as defined by the Minnesota (MN) GVHD Ris
228 tional Cancer Institute [NCI] standard risk [SR]: AALL0331; NCI high risk: AALL0232) were included.
229 dition treatments) and Cu in seedling roots (SRs) were 1.45 and 1.58 times those in soil, respectivel
230 role of JNK2 in the function of the SERCA2 (SR Ca(2+)-ATPase), essential in maintaining SR Ca(2+) co
233 nd submicro-X-ray fluorescence spectroscopy (SR-XRF), gadolinium was detected in human cortical bone
234 L-1-cardiomyocytes) and enhanced spontaneous SR Ca(2+)-release events in both POAF cardiomyocytes and
236 ESRF and Diamond Light Source using submicro-SR-XRF allowed resolving thin Gd structures in cortical
241 eotide, small-molecule STING agonist, termed SR-717, that demonstrates broad interspecies and interal
245 rotation and relaxation ([Formula: see text]SR) technique ideal for probing ions dynamics in these t
248 us attrition/induction decay hypothesis that SR Ca(2+) release events terminate below a threshold Ca(
249 8-angstrom cocrystal structure revealed that SR-717 functions as a direct cyclic guanosine monophosph
250 ollection behavior in reproduction such that SR is more homogeneous among families than expected by c
252 ally, recent work intriguingly suggests that SR may be found at the postsynaptic density, yet the fun
255 ects of 9AC demonstrate that P(i) enters the SR via a Cl(-) pathway of an as-yet-undefined molecular
256 pathological diastolic Ca(2+) leak from the SR that both triggers arrhythmias and impairs contractil
257 R2 channels and prevent Ca(2+) leak from the SR, are undergoing investigation in clinical trials.
260 ent size distribution of most vessels in the SR images was below 80 um and agrees with micro-CT data,
262 olic calcium level in the cytosol and in the SR must fulfill simultaneously two different equalities.
264 main pathway of inorganic phosphate into the SR and confirm that P(i) impairs Ca(2+) release by accum
271 ned by a direct effect of P(i) acting on the SR Ca(2+) release channel, combined with the intra-SR pr
272 h the bacterial SRP further suggest that the SR MoRF functionally replaces the essential GNRA tetralo
275 also has a therapeutic effect itself through SR-B1-mediated intracellular cholesterol depletion in SH
277 ophage-specific overexpression of urokinase (SR-uPA(+/0) mice) and of SR-uPA(+/0) bone marrow transpl
278 w inspiration from natural systems which use SR to detect and amplify low-amplitude signals, to demon
282 es the major HDL-dependent m-RCT pathway via SR-BI (scavenger receptor class B type 1) to the liver,
285 me to regulate its interaction kinetics with SR, thereby reducing the nonspecific targeting of signal
286 re excellent for this group of patients with SR ALL, with particularly good outcomes for those with S
289 ddition of IC to treatment for patients with SR-average disease did not improve CCR or OS, even in pa
292 among 635 nonrandomly treated patients with SR-high disease were 85.55% +/- 1.49% and 92.97% +/- 1.0
301 he major TRIC-subtype in skeletal muscle, WT SR will predominantly contain TRIC-A channels, whereas T
302 In vivo studies using syngeneic SR-B1 WT (SR-B1(+/+)) and SR-B1 KO (SR-B1(-/-)) prostate cancer ce