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1 SRP fosters interweaving multiple knowledge resources to
2 SRP has had many successes: discovery of arsenic's toxic
3 SRP is also known to contact the ribosome at this site.
4 SRP is coordinated by the National Institute of Environm
5 SRP must continue to address the legacy of hazardous was
6 SRP of inflamed moderate pockets during 6-month PMT, wit
7 SRP plus different adjunctive therapies could provide be
8 SRP scans the nascent chains of translating ribosomes, p
9 SRP together with medical treatment results in a greater
12 omly allocated to three treatment groups: 1) SRP with placebo gel (group 1); 2) SRP with 1.2% RSV gel
15 roups: 1) SRP with placebo gel (group 1); 2) SRP with 1.2% RSV gel (group 2); and 3) SRP with 1.2% AT
18 oups: 1) NT group (n = 30), no treatment; 2) SRP group (n = 30), scaling and root planing (SRP) and l
19 with: 1) at least 6 months of follow-up; 2) SRP, in combination with local antimicrobials; and 3) pa
22 ion with physiologic saline solution; and 3) SRP/SA group (n = 30), SRP and local irrigation with SA
28 shes the ability of the ribosome to activate SRP-SR assembly and impairs cotranslational protein targ
32 ed in the control group 3 and 6 months after SRP, matrix metalloproteinase-8 level decreased in the t
37 ial complexes did not differ between MTZ+AMX+SRP and SRP-only groups at 5 years post-treatment (P > 0
38 membrane via a Dynamic mode, followed by an SRP-induced conformational transition to a Stable mode t
45 lexes did not differ between MTZ+AMX+SRP and SRP-only groups at 5 years post-treatment (P > 0.05).
46 milar groups, SRP + MM (aged 66.8 years) and SRP alone (aged 67 years), to treat a >/=5 mm posterior
50 In muscle biopsies of patients with anti-SRP(+) and anti-HMGCR(+) Abs, a large number of small fi
52 c analyses and comparison with the bacterial SRP further suggest that the SR MoRF functionally replac
53 The precise mechanism by which the bacterial SRP receptor, FtsY, interacts with and is regulated at t
54 he essential GNRA tetraloop in the bacterial SRP RNA, providing an example for the replacement of RNA
58 ns are still known to be independent of both SRP and GET, so there seems to be a critical need for an
59 pecific semantic predictions were indexed by SRP sources within the motor system-in dorsolateral hand
60 the canonical cotranslational recognition by SRP, SRP was found to bind to YohP posttranslationally.
61 eceiving non-surgical periodontal therapy by SRP with (test) and without (control) two appointments o
63 plast of green plants, where the chloroplast SRP (cpSRP) post-translationally targets light-harvestin
65 masked, randomized clinical trial comparing SRP with placebo (placebo + SRP group, n = 26) or SRP co
66 uggest coevolution of the two most conserved SRP features-SRP RNA helix 8 and Srp54-in basidiomycetes
77 tivity over existing approaches allowing for SRP measurements of unprecedented frequency (8 min), whi
78 eins, which we name Snd1, Snd2 and Snd3 (for SRP-independent targeting), can synthetically compensate
80 tudy) into two statistically similar groups, SRP + MM (aged 66.8 years) and SRP alone (aged 67 years)
82 utational approaches have failed to identify SRP components from genomes of many lower eukaryotes, ra
84 % (down to 38% of patients) and 95% (26%) in SRP + MM and 82% (42%) and 82% (41%) in SRP at 6 and 12
87 ates key interactions between two GTPases in SRP and its receptor, thus enabling rapid delivery of ca
88 (0.9 +/- 0.8 mm) and 13% (0.7 +/- 0.9 mm) in SRP + MM and 11% (0.7 +/- 1.1 mm) and 21% (1.2 +/- 0.9 m
91 metic drug ketamine, play a critical role in SRP, but not in the induction or expression of adult OD
95 as not strongly related to lake TP, and lake SRP concentrations were positively but weakly related to
96 e, we present structures of native mammalian SRP-ribosome complexes in the scanning and engaged state
100 e of locally delivered statins to mechanical SRP is beneficial to increasing bone fill percentage.
103 hat if disease-associated mutations obstruct SRP interaction, they lead to silencing of the mutated p
104 retained on average 37% of NO3-N and 45% of SRP inputs, with maximum retention exceeding 60% and 80%
106 ence analyses showed that, in the absence of SRP RNA, the M-domain of cpSRP54 both accelerates and st
109 RNA is a universally conserved component of SRP that mediates key interactions between two GTPases i
114 trolled trial was to compare the efficacy of SRP with and without adjunct probiotic therapy (PT) in t
115 V1 play a critical role in the expression of SRP and its behavioral correlate of familiarity recognit
119 and remodels the conformational landscape of SRP on the ribosome to regulate its interaction kinetics
123 nstrates that the NAC-induced regulations of SRP activity are essential for the fidelity of cotransla
125 ith placebo (placebo + SRP group, n = 26) or SRP combined with a 6-month regimen of 400 mg oral propo
128 cture of the closed state reveals an ordered SRP RNA and SRP M domain with a signal sequence-bound.
132 ions of total P (TP) and soluble reactive P (SRP) with no discernable annual or seasonal patterns.
134 al targeting by signal recognition particle (SRP) and posttranslational targeting by SecA and SecB.
136 targeting, the signal recognition particle (SRP) binds to the translating ribosome displaying the si
137 sally conserved signal recognition particle (SRP) co-translationally delivers newly synthesized membr
140 ervation of the signal recognition particle (SRP) from bacteria to man, computational approaches have
142 sally conserved signal recognition particle (SRP) is essential for the biogenesis of most integral me
143 tionally by the signal recognition particle (SRP) pathway or post-translationally by the mammalian tr
144 f the mammalian signal recognition particle (SRP) receptor and conserved among eukaryotes, plays an e
147 cognized by the signal recognition particle (SRP)(3,4) and then moved co-translationally through the
148 te selection by signal recognition particle (SRP), a universally conserved protein targeting machine.
149 cognized by the signal recognition particle (SRP), as indicated by in vivo and in vitro site-directed
151 equired for the signal recognition particle (SRP), SRP receptors, the translocon, the signal peptidas
152 MetAP), and the signal recognition particle (SRP), which targets secretory and membrane proteins to t
160 s (NH4-N, NO3-N, soluble reactive phosphorus-SRP) along a approximately 300-km arid-land river (Rio G
161 trial comparing SRP with placebo (placebo + SRP group, n = 26) or SRP combined with a 6-month regime
162 RP group (n = 30), scaling and root planing (SRP) and local irrigation with physiologic saline soluti
164 use to mechanical scaling and root planing (SRP) and placebo in each group, with minimum 10 particip
166 ) as an adjunct to scaling and root planing (SRP) for treating chronic periodontitis in patients with
168 prophylaxis before scaling and root planing (SRP) has an effect on the outcome of non-surgical period
170 , as an adjunct to scaling and root planing (SRP) in the treatment of intrabony defects in chronic pe
171 l as an adjunct to scaling and root planing (SRP) in the treatment of moderate and severe chronic per
172 d as an adjunct to scaling and root planing (SRP) in the treatment of patients with type 2 diabetes m
173 MX) as adjuncts to scaling and root planing (SRP) in the treatment of periodontitis in type 2 diabeti
174 ate the effects of scaling and root planing (SRP) on clinical parameters and circulating levels of le
176 with conventional scaling and root planing (SRP) over weeks or same-day full-mouth disinfection (FDI
177 riodontal therapy, scaling and root planing (SRP) per quadrant and one-stage full-mouth disinfection
178 e effectiveness of scaling and root planing (SRP) plus the adjunctive use of diode laser therapy to S
179 s as an adjunct to scaling and root planing (SRP) provide additional benefits in the treatment of per
180 ndomized following scaling and root planing (SRP) to receive ERL monotherapy (n = 27) or MIST (n = 26
182 er study evaluated scaling and root planing (SRP) with and without EMD in 51 patients presenting with
183 Effectiveness of scaling and root planing (SRP) with/without adjunct probiotic (Lactobacillus reute
184 therapy, including scaling and root planing (SRP), and were assigned randomly to a test (SRP + probio
185 ms, in addition to scaling and root planing (SRP), for the treatment of intrabony defects (IBDs) in p
186 In 1- to 3-mm PD, scaling and root planing (SRP), modified Widman flap (MWF), and osseous surgery (O
187 ) over traditional scaling and root planing (SRP), with or without adjunctive metronidazole, when tre
192 riodontal therapy (scaling and root planing [SRP]) on gingival interleukin (IL)-1beta and IL-10, seru
193 patients received scaling and root planning (SRP), per quadrant at a 1-week-interval, performed with
194 Ps) coated with stimuli-responsive polymers (SRPs) exhibit tunable optical properties responding to e
197 ents that do not use any form of ST product, SRP is an effective treatment modality for the treatment
198 ssel-beam-based stimulated Raman projection (SRP) microscopy and tomography for label-free volumetric
199 400 mg oral propolis once daily (propolis + SRP group, n = 24) was performed in patients with long-s
200 with either anti-signal recognition protein (SRP) or anti-3-hydroxy-3-methylglutaryl-CoA reductase (H
207 lar bone levels between the groups receiving SRP and vitamins and the group receiving SRP alone.
208 emerging from the 60S tunnel, which recruit SRP/Sec61 to the shared binding site, displace Ebp1.
210 .4%, 6.5%, and 5.22% CAL gain, respectively; SRP, MWF, and OS resulted in 18.7%, 25.4%, and 30.8% PD
211 %, 39.4%, and 61.39% CAL loss, respectively; SRP, MWF, and OS resulted in increased mean PD of 2.5%,
212 d for the signal recognition particle (SRP), SRP receptors, the translocon, the signal peptidase comp
216 tory and requiring antibiotics to supplement SRP were associated with low biofilm lysine contents.
218 (SRP), and were assigned randomly to a test (SRP + probiotic, n = 14) or control (SRP + placebo, n =
219 MWF had significantly more PD reduction than SRP, and there was significantly less CAL gain with surg
221 and proteoliposome studies demonstrated that SRP and its receptor FtsY are essential for the posttran
227 cant differences were identified between the SRP and FMD groups in regard to OHQoL and OIDP scores wh
228 etically compensate for the loss of both the SRP and GET pathways, and act as a backup targeting syst
229 less hydrophobic signal sequences bypass the SRP and are moved through the channel post-translational
231 r plant chloroplasts from cyanobacteria, the SRP pathway underwent striking adaptations that enable t
232 SRP and sample rotation, we demonstrate the SRP tomography that can reconstruct the 3D distribution
237 There were fewer TRAP-positive cells in the SRP/SA group than in the NT group at all of the time poi
242 ing machinery permits the permutation of the SRP RNA and creates highly stable and functional circula
243 tidomain chloroplast-specific subunit of the SRP, cpSRP43, is proposed to take on the role of coordin
247 e translating Escherichia coli ribosome, the SRP-SR in the 'activated' state and the translocon.
249 ions in the RNA-binding domain of Srp54, the SRP protein subunit that directly interacts with helix 8
250 by biochemical experiments, reveals that the SRP RNA adopts a kinked and untwisted conformation to al
251 oluble ribosome footprints revealed that the SRP-dependent membrane targeting of PsbA is already init
252 ing the signal sequence to deliver it to the SRP receptor (SR) on the membrane, where the signal pept
253 gets ribosome-nascent chain complexes to the SRP receptor in the endoplasmic reticulum membrane, init
255 recruitment of the SRP receptor FtsY to the SRP-RNC complex results in GTP-independent binding of th
256 e reactions with chemical accuracy using the SRP-DFT approach, as has been shown for H2 + Cu(111) and
262 use of local antimicrobials as an adjunct to SRP may result in additional benefits compared with SRP
263 nce daily is a potentially viable adjunct to SRP that significantly reduces levels of HbA1c, FPG, and
264 cts of local antimicrobials as an adjunct to SRP, compared with SRP alone, on periodontal clinical pa
266 tion of four sessions of aPDT, adjunctive to SRP, promotes additional clinical, microbiologic, and im
267 ded that topical use of SA as an adjuvant to SRP is effective in the treatment of experimental period
268 id not enhance clinical outcomes compared to SRP alone in the treatment of inflamed sites with >/= 5
272 the adjunctive use of diode laser therapy to SRP alone on changes in the clinical parameters of disea
274 tress on non-surgical periodontal treatment (SRP) outcomes in patients with severe chronic periodonti
277 e; 2) group 2: Shamma-chewers that underwent SRP + PT; 3) group 3: Non-chewers that underwent SRP alo
278 s: 1) group 1: Shamma chewers that underwent SRP alone; 2) group 2: Shamma-chewers that underwent SRP
279 + PT; 3) group 3: Non-chewers that underwent SRP alone; and 4) group 4: Non-chewers that underwent SR
281 ur data revealed that YohP engages an unique SRP-dependent posttranslational insertion pathway that i
287 result in additional benefits compared with SRP alone in PD reduction and CAL gain, especially in we
288 crobials as an adjunct to SRP, compared with SRP alone, on periodontal clinical parameters of patient
291 onstrate that they function in parallel with SRP and GET to target a broad range of substrates to the
292 d analysis, patients in group 2 treated with SRP + 0.5% AZM showed enhanced reductions in PI, GI, mSB
297 nt IBD depth reduction at sites treated with SRP plus locally delivered MF in patients with CP in bot
298 BDs was randomly allocated to treatment with SRP followed by LDD of 1.2% RSV, 1.2% ATV, or placebo ge
300 DASS-stress score was associated to worsened SRP outcomes in terms of bleeding on probing (BOP) (OR =