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1 SRS followed by EGFR-TKI resulted in the longest OS and
2 SRS is a nonlinear technique that probes the same vibrat
3 SRS is typically administered in a single session but ca
4 SRS microscopy offers an imaging speed that is faster th
5 SRS microscopy was used to image D2O, PG-d8/DMSO-d6, and
6 SRS relies on the precisely guided delivery of high-dose
7 SRS revealed interactions between the gel and the stratu
8 SRS was applied to image label-free ponatinib with high
10 randomized participants (SRS alone, n = 111; SRS plus WBRT, n = 102) with a mean age of 60.6 years (S
16 ce of cognitive deterioration was less after SRS alone at 3 months (5/11 [45.5%] vs 16/17 [94.1%]; di
17 ss cognitive deterioration at 3 months after SRS alone (40/63 patients [63.5%]) than when combined wi
18 -up, performed between 4 and 15 months after SRS, all 3 patients demonstrated a reduction in uveal tu
19 ration and detection strategies have allowed SRS to probe increasingly smaller volumes and shorter ti
20 disease progression (of which 47% were also SRS-positive) were deceased, and 87% of patients with a
24 er-adjusted associations between 52 EDCs and SRS scores using a two-stage hierarchical analysis to ac
26 gene expression profiling was performed and SRS endotype was determined by a previously established
28 t applications of both spontaneous Raman and SRS as novel imaging platforms to facilitate the drug di
35 polarization ratios measured using broadband SRS agree with the limited number of previously reported
36 water, benzene, and toluene using broadband SRS with femtosecond and picosecond Raman pump pulses at
39 zes the rich chemical information offered by SRS imaging, and an improved diagnosis can be achieved i
41 ly mild symptoms from brainstem compression, SRS can be recommended as the primary therapy with the a
44 tegration within (local efficiency) the DMS, SRS, and FPS, and between (participation coefficient) th
45 Social Responsiveness Scale, second edition [SRS-2], with T scores of >/=75 associated with a categor
46 ed (1:1) with a block size of four to either SRS of the resection cavity (within 30 days of surgery)
47 dren whose parents had concordantly elevated SRS scores (odds ratio [OR], 1.85; 95% CI, 1.08-3.16) an
51 l-focusing stimulated Raman scattering (FMSF-SRS) microscopy: a technical improvement over traditiona
55 Median overall survival was 10.4 months for SRS alone and 7.4 months for SRS plus WBRT (hazard ratio
56 10.4 months for SRS alone and 7.4 months for SRS plus WBRT (hazard ratio, 1.02; 95% CI, 0.75-1.38; P
57 of a 5-week continuous monitoring period for SRS, quantitative immunohistochemistry using neuronal (n
59 (mean change from baseline, -1.5 points for SRS alone vs -4.2 points for SRS plus WBRT; mean differe
60 -1.5 points for SRS alone vs -4.2 points for SRS plus WBRT; mean difference, 2.7 points; 95% CI, -2.0
61 ndings from our study may have relevance for SRS and highlight a potentially underreported aspect of
62 ranial failure was significantly shorter for SRS alone compared with SRS plus WBRT (hazard ratio, 3.6
65 that both lymphoblasts and fibroblasts from SRS patients can accumulate Me(2)SPM, resulting in signi
71 ncluding the Social Responsiveness Scale-II (SRS-2) as a measure of autistic traits and social impair
72 in brain tissue, the organ most affected in SRS, and was associated with changes in polyamine metabo
74 estimated covariate-adjusted differences in SRS-2 T-scores with a doubling in phthalate concentratio
77 omponent explaining 30.9% of the variance in SRS-2 scores, and a strong association with ADHD symptom
79 ing any optical imaging technique, including SRS, there is an additional problem of optical aberratio
82 f patients likely to benefit from first-line SRS, close CNS observation, and treatment of emergent CN
84 er, in patients not suited for microsurgery, SRS might also be an alternative to balance tumor contro
85 Further, on the basis of the multiplexed SRS images concurrently highlighting the cellular protei
86 volumetric phasor analysis of multispectral SRS images for chemically specific clustering and segmen
88 providing an ablative effect noninvasively, SRS has altered the treatment paradigms for benign and m
89 This previously unreported application of SRS has permitted, therefore, direct visualization and s
90 oteins and lipids by linear decomposition of SRS images at three optimally selected Raman shifts.
92 sible for the patients having a mild form of SRS and reveal yet another molecular mechanism resulting
94 ates the pathological polyamine imbalance of SRS and causes survival defects and synaptic degeneratio
95 ackground and experimental implementation of SRS microscopy are discussed and recent developments in
96 affecting males, the main manifestations of SRS include osteoporosis, hypotonic stature, seizures, c
104 ll hearing preservation rate and toxicity of SRS was influenced by age and cannot be predicted by tum
105 ive, multi-institutional randomized trial of SRS followed by EGFR-TKI versus EGFR-TKI followed by SRS
107 nts with 1 to 3 brain metastases, the use of SRS alone, compared with SRS combined with WBRT, resulte
109 chemical information can maximize the use of SRS during intraoperative pathologic consultation with i
111 We aimed to categorize patients based on SRS endotypes to determine if these profiles influenced
112 for the detection of primary NETs occult on SRS, especially tumors with a well-differentiated patter
113 assigned to the observation group (n=68) or SRS group (n=64), with 128 patients available for analys
115 metastases were randomized to receive SRS or SRS plus WBRT between February 2002 and December 2013.
117 ing algorithm, we obtain robust single-pixel SRS spectra exhibiting single-molecule events, verified
119 BPA concentration was associated with poorer SRS-2 scores [beta=0.3 ( 95% CI: 0, 0.7)]; this associat
121 er for the patient group that had a positive SRS than the group with a negative SRS (P = 0.0002).
122 group with a low-grade GEPNET and a positive SRS, PFS and OS were also significantly lower for patien
124 domly assigned (1:1) to either postoperative SRS (12-20 Gy single fraction with dose determined by su
126 therapy (WBRT) or stereotactic radiosurgery (SRS) delivered only to the radiographically visible tumo
130 y to determine if stereotactic radiosurgery (SRS) to the surgical cavity improved time to local recur
132 identified during stereotactic radiosurgery (SRS) treatment planning, which is time consuming and pot
136 n the brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive decl
137 apy to the brain (stereotactic radiosurgery [SRS] or whole-brain radiotherapy [WBRT]), and 86 of 90 r
139 -rearranged NSCLC treated with radiotherapy (SRS and/or WBRT) and TKIs have prolonged survival, sugge
141 brain metastases were randomized to receive SRS or SRS plus WBRT between February 2002 and December
143 s was less frequent in patients who received SRS than those who received WBRT (28 [52%] of 54 evaluab
144 our findings show that pseudo-H&E recolored SRS images in combination with lipid and protein chemica
145 arch for a molecular cause for the remaining SRS cases, and to find a possible common epigenetic chan
147 r status epilepticus (SE) greatly restrained SRS and alleviated cognitive, memory, and mood dysfuncti
148 e participants, 2144 nurses (67.8%) returned SRS forms for a child and at least 1 parent and were inc
149 to the default mode (DMS), salience/reward (SRS), and frontoparietal (FPS) subnetworks in rMDD patie
150 ere identified using simple random sampling (SRS) in Nayapara and multistage cluster sampling in MSs
151 lysis using the Social Responsiveness Scale (SRS) revealed that the relationship between EQ-C and mat
154 hecklist (ABC), Social Responsiveness Scale (SRS), and Clinical Global Impression Improvement Scale (
159 02, measured by Social Responsiveness Scale [SRS] score), which contrasts with families where the phe
160 rospectroscopy, stimulated Raman scattering (SRS) and laser scanning confocal imaging, and microtome
162 Hyperspectral stimulated Raman scattering (SRS) imaging has rapidly become an emerging tool for hig
163 ous two-channel stimulated Raman scattering (SRS) imaging technique and a new pseudo-hematoxylin and
164 al of employing stimulated Raman scattering (SRS) imaging to probe for metabolic differences between
168 this method to stimulated Raman scattering (SRS) microscopy and systematically identify 57 Caenorhab
169 py, followed by stimulated Raman scattering (SRS) microscopy and transcriptomics analysis, we identif
170 f hyperspectral stimulated Raman scattering (SRS) microscopy associated with a Raman tag synthesized
171 emonstrate that stimulated Raman scattering (SRS) microscopy can be used to provide sensitive and qua
172 emonstrate that stimulated Raman scattering (SRS) microscopy could be used to sensitively monitor per
174 ing method with stimulated Raman scattering (SRS) microscopy for visualization of the cell nuclei in
175 n a decade ago, stimulated Raman scattering (SRS) microscopy has become a powerful modality for imagi
178 tical technique stimulated Raman scattering (SRS) microscopy promises a solution, as it can rapidly m
179 ring (CARS) and stimulated Raman scattering (SRS) microscopy provide label-free chemically specific i
182 ombination with stimulated Raman scattering (SRS) microscopy, define a role for BMP signaling in lipi
187 application of stimulated Raman scattering (SRS) uses the benefit of a label-free molecular fingerpr
188 development of stimulated Raman scattering (SRS), and covers the use of bioorthogonal tags to enhanc
192 ogenesis and spontaneous recurrent seizures (SRS) an impairment of the endogenous anti-inflammatory p
194 alleviating spontaneous recurrent seizures (SRS) or cognitive, memory, and mood impairments has neve
197 atients with spontaneous splenorenal shunts (SRS) is a matter of concern especially in case of large
198 We identified two sepsis response signature (SRS) subgroups in fecal peritonitis associated with earl
201 al basin located on the Savannah River Site (SRS) has concentrated in a wetland 600 m downstream.
203 soil collected from the Savannah River Site (SRS) or unamended vadose zone soil and exposed to 3 year
204 for high U retention by Savannah River Site (SRS) wetland sediments under varying redox and acidic (p
205 cility in F-Area of the Savannah River Site (SRS), USA, were approximately 2.5 times greater than tho
209 ly evidenced by scanning Raman spectroscopy (SRS) and scanning electron microscopy coupled with energ
210 ombination of stimulated Raman spectroscopy (SRS) and surface-enhanced Raman scattering (SERS) using
211 ave employed statistical Raman spectroscopy (SRS), and a forefront characterization tool using thermo
212 t scores, and summed difference scores (SSS, SRS, and SDS [respectively] = SSS-SRS) were evaluated us
213 ores (SSS, SRS, and SDS [respectively] = SSS-SRS) were evaluated using 17-segment visual interpretati
215 Patients with Snyder-Robinson Syndrome (SRS) exhibit deficient Spermidine Synthase (SMS) gene ex
217 esis enzyme, cause Snyder-Robinson syndrome (SRS), an X-linked intellectual disability syndrome; howe
222 enes belonging to the MYB, HD-ZIP, ERF, TCP, SRS, WRKY and DOF families may be involved in the regula
223 es belonging to HD-ZIP, ERF, WRKY, MYB, TCP, SRS and DOF families may be the major players in the reg
224 Raman scattering is an incoherent technique, SRS is a coherent process, and this fact provides severa
226 ur approach exhibits higher sensitivity than SRS imaging of DNA in the fingerprint spectral region.
231 erging data exist to support the notion that SRS in combination with targeted therapies or immune the
238 irritated, had less connections between the SRS and other subnetworks and higher local efficiency co
239 scores of autistic traits as measured by the SRS-2 in boys, but not girls; these small size effects w
242 dose schedule was 30 Gy in 12 fractions; the SRS dose was 18 to 22 Gy in the SRS plus WBRT group and
244 ant roots can highly immobilize U(VI) in the SRS acidic sediments, which has significant implication
245 assessment committee identified gaps in the SRS for prioritization and intervention and piloted the
246 the observation group and 72% (60-87) in the SRS group (hazard ratio 0.46 [95% CI 0.24-0.88]; p=0.015
247 impairment (three [3%] of 93 patients in the SRS group vs eight [9%] of 92 patients in the WBRT group
252 strategy enables detailed monitoring of the SRS environment, revealing plutonium isotopic compositio
253 nterferences, and a linear dependence of the SRS signal on the TPP concentration, we successfully est
260 e distal domains and clear homology with the SRS-domain containing proteins of Toxoplasma gondii.
263 ecifically, the technology enables real-time SRS-image-based sorting of single live cells with a thro
266 survival was longer in patients assigned to SRS (median 3.7 months [95% CI 3.45-5.06], 93 events) th
267 8 [52%] of 54 evaluable patients assigned to SRS vs 41 [85%] of 48 evaluable patients assigned to WBR
268 Pu/(239+240)Pu activity ratios attributed to SRS are substantially different than fallout due to past
272 rations exhibited significantly higher total SRS T-scores, indicating greater overall social impairme
275 py: a technical improvement over traditional SRS microscopy that effectively removes imaging backgrou
276 e potential therapeutic targets for treating SRS and other polyamine-associated neurological disorder
281 at operated at the Savannah River Site, USA (SRS) decades ago, trace quantities of plutonium with hig
286 show that single cell metabolic imaging via SRS microscopy can be used for rapid detection of antimi
288 xa at 1, 2, and 3 years were associated with SRS-2 performance, including many in the Lachnospiraceae
290 e children were examined in association with SRS scores of the parents using crude and adjusted linea
291 astases, the use of SRS alone, compared with SRS combined with WBRT, resulted in less cognitive deter
292 ficantly shorter for SRS alone compared with SRS plus WBRT (hazard ratio, 3.6; 95% CI, 2.2-5.9; P < .
295 Biochemically, the cells of individuals with SRS accumulate excess spermidine, whereas spermine level
296 Quality of life was higher at 3 months with SRS alone, including overall quality of life (mean chang
298 nction was more frequent with WBRT than with SRS and there was no difference in overall survival betw
300 e brain metastasis or initial treatment with SRS versus WBRT were not (P = .633 and .666, respectivel