ライフサイエンスコーパス: Salmonella infection

1 esis as well as heightened susceptibility to Salmonella infection.

2 ive Salmonella, a phenotype resembling human Salmonella infection.

3 es M cells and SFB levels to protect against Salmonella infection.

4 se can serve as a good animal model to study Salmonella infection.

5 synthesis or modification mainly during the Salmonella infection.

6 ed Ab had little deficiency in resistance to Salmonella infection.

7 role of SIRPalpha for protective immunity to Salmonella infection.

8 ded mice with significant protection against Salmonella infection.

9 ythropoiesis and increased susceptibility to Salmonella infection.

10 ion and systemic inflammation in response to Salmonella infection.

11 lagellin-specific CD4 T cells following oral Salmonella infection.

12 lic abnormalities, or enhanced resistance to Salmonella infection.

13 s and optimal protective immunity to primary Salmonella infection.

14 massive erythropoiesis occurs in response to Salmonella infection.

15 ell death ligand 1) in resistance to primary Salmonella infection.

16 and the resulting susceptibility to enteric Salmonella infection.

17 xacerbates mucosal inflammatory responses to Salmonella infection.

18 demonstrate a global macrophage response to Salmonella infection.

19 hepatobiliary system as the site of chronic Salmonella infection.

20 their host cell targets during each stage of Salmonella infection.

21 showed increased susceptibility to systemic Salmonella infection.

22 es cecal colonization during early stages of Salmonella infection.

23 hese changes conferred greater resistance to Salmonella infection.

24 4 T cells, which are crucial for immunity to Salmonella infection.

25 bably are an underrecognized source of human salmonella infection.

26 innate and adaptive immune responses during Salmonella infection.

27 nt during, and immediately following, active Salmonella infection.

28 neutral sphingolipids did not increase upon Salmonella infection.

29 reversed the deleterious effects of in vivo Salmonella infection.

30 ession in intestinal tissues is increased by Salmonella infection.

31 ation of IL-10 production, and resistance to Salmonella infection.

32 ssion of T-bet is required for resistance to Salmonella infection.

33 inflammation, anemia, and susceptibility to Salmonella infection.

34 role of the chemokine CCL2 in the control of Salmonella infection.

35 dulation on NKT cells in the setting of oral Salmonella infection.

36 age may be important in the establishment of Salmonella infection.

37 d Th17 responses in ex-germ-free mice during Salmonella infection.

38 mice (carrying mutated TLR-4) in response to Salmonella infection.

39 le of IFN-alpha/beta in the host response to Salmonella infection.

40 enotypic response of different cell lines to Salmonella infection.

41 ains of salmonella is rare, as is nosocomial salmonella infection.

42 kout (KO) mice are susceptible profoundly to Salmonella infection.

43 e capacity to protect naive mice from lethal Salmonella infection.

44 ion of IL-18 secretion by macrophages due to Salmonella infection.

45 e expression to the appropriate times during Salmonella infection.

46 recognized by murine T cells responding to a Salmonella infection.

47 or SCF:c-kit interactions in host defense to Salmonella infection.

48 be an important intestinal tract response to Salmonella infection.

49 ogenase LldD in vitro and in mouse models of Salmonella infection.

50 Lsh/Bcg locus and in their susceptibility to Salmonella infection.

51 so dampened the inflammatory response during Salmonella infection.

52 at IL-1beta production is detrimental during Salmonella infection.

53 ain (NICD) and Hes1 were decreased following Salmonella infection.

54 ellular bacterial restriction in the case of Salmonella infection.

55 in nucleation and polymerization defect upon Salmonella infection.

56 targeted for therapy of diarrhoea caused by Salmonella infection.

57 notypic variation in their susceptibility to Salmonella infection.

58 component of the host defense machinery upon Salmonella infection.

59 and functional files, and susceptibility to Salmonella infection.

60 te host defense in homeostasis and following Salmonella infection.

61 anode, which is reversed to the cathode upon Salmonella infection.

62 sible for variation in the susceptibility to Salmonella infection.

63 isease tolerance pathways in endotoxemia and Salmonella infection.

64 ption of raw food as a major risk factor for Salmonella infection.

65 erform lactate fermentation, thus supporting Salmonella infection.

66 onferred crucial protection against systemic Salmonella infection.

67 ntestinal microbial community in response to Salmonella infection.

68 similar to those of wild-type mice following Salmonella infection.

69 ins of the host tryptophan metabolism during Salmonella infection.

70 s new candidates potentially associated with Salmonella infection.

71 -331-3p in regulation of immune responses to Salmonella infection.

72 at may potentially regulate host response to Salmonella infection.

73 ucella but found that it is not required for Salmonella infection.

74 L-17RA expression was generally unchanged in Salmonella infection.

75 way are predisposed to invasive nontyphoidal Salmonella infection.

76 imulation hindered the resolution of primary Salmonella infection.

77 tions and play a crucial role in controlling Salmonella infection.

78 he pathophysiological impact of STAT4 during Salmonella infection.

79 le for cell death associated caspases during Salmonella infection.

80 e to drive robust IL-1beta processing during Salmonella infection.

81 t of inflammatory cells to the spleen during Salmonella infection.

82 duced the adverse effects of H. polygyrus on Salmonella infection.

83 ble phenotype of IFN-gamma-deficient mice to Salmonella infection.

84 e distinct effector functions in response to Salmonella infection.

85 08, we investigated a nationwide outbreak of salmonella infections.

86 l strategies to diagnose, treat, and prevent Salmonella infections.

87 lence in herds is important to prevent human Salmonella infections.

88 contributes to proinflammatory responses to Salmonella infections.

89 previously unrecognized specific features of Salmonella infections.

90 ty enhanced the clearance of multiple-strain Salmonella infections.

91 flammatory cytokines which is typical during Salmonella infections.

92 ating toxin critical for the pathogenesis of Salmonella infections.

93 presenting with fever of unknown origin for Salmonella infections.

94 mediators of resistance to extra-intestinal Salmonella infections.

95 ost cells is crucial for the pathogenesis of Salmonella infections.

96 cellular ATP to confer resistance to enteric Salmonella infections.

97 had significantly higher inflammation after Salmonella infections.

98 nce-associated secreted factor that enhances Salmonella infections.

99 e among the drugs of choice for treatment of Salmonella infections.

100 had significantly higher inflammation after Salmonella infections.

101 of antibacterial strategies to fight against Salmonella infections.

102 ndary protection against otherwise lethal WT Salmonella infections.

103 REI-Bs studied (beach water exposure [OR for Salmonella infection, 28.3 {CI, 7.2-112.2}; OR for Shige

104 ed was associated with a significant risk of salmonella infection (4 of 5 patients had taken fluoroqu

105 Of 52,821 (>96%) geocodable Salmonella infections, 48,111 (91.1%) were domestically-

106 In a mouse model of Salmonella infection, a subset of infected hosts becomes

107 In addition, Salmonella infection activated a proinflammatory immune

108 In contrast, Salmonella infection activated caspase-1 through an inde

109 Salmonella infection activated the kinase c-Jun N-termin

110 Salmonella infections affect millions worldwide and rema

111 regulate a maximal innate immune response to Salmonella infection, allowing a sustained inflammatory

112 Salmonella infection also upregulates PD-L1 levels; howe

113 lular proliferation within host cells during Salmonella infections, although none have been found to

114 The seroincidence of typhoidal Salmonella infection among children younger than 5 years

115 e know quite a bit about the epidemiology of Salmonella infection among domestic fowl, we know little

116 susceptibility to atypical mycobacterial and salmonella infections among individuals whose lymphocyte

117 igate the contribution of IL-18 to resolving Salmonella infections, an attenuated aro-negative mutant

118 Peyer patches are the major entrance of Salmonella infection and antigen transportation in intes

119 lls are activated within a few hours of oral Salmonella infection and are essential for protective im

120 as a susceptibility factor for disseminated Salmonella infection and arginine as a central metabolit

121 We find that Rab32 interacts with IRG1 on Salmonella infection and facilitates the delivery of ita

122 We monitored spleen cell populations during Salmonella infection and found that the most prominent i

123 we examine the relationship between systemic Salmonella infection and thymic function.

124 ntibacterial effect within macrophages after Salmonella infection and to sensitize host cells to Salm

125 re essential for resistance against systemic Salmonella infections and can express the highest protec

126 he pathogenesis of typhoid and non-typhoidal Salmonella infections and demonstrate the utility of hum

127 an established risk factor for nontyphoidal Salmonella infections and outbreaks.

128 firms the importance of PMN in resistance to Salmonella infections and shows that this is facilitated

129 etermining the outcome of naturally acquired Salmonella infections and that both vaccine formulation

130 nal surveillance methods for the evidence of Salmonella infections and to determine the extent of out

131 Caspase-3 was not activated during Salmonella infection, and PARP remained in its active, u

132 Outbreaks of human salmonella infections are increasingly associated with c

133 nd intermittent fecal shedding, hallmarks of Salmonella infections, are important for fecal-oral tran

134 Morphine withdrawal sensitized mice to Salmonella infection, as evidenced by increased mortalit

135 e, have attenuated inflammatory responses to Salmonella infection associated with decreased macrophag

136 data show that morphine markedly potentiates Salmonella infection at the gastrointestinal portal of e

137 During Salmonella infection, bacteria remain enclosed by lysoso

138 Patients with ceftriaxone-resistant Salmonella infections between 1996 and 1998 were intervi

139 reography of gene expression is required for Salmonella infection, but basic genetic information such

140 BP-independent manner were more resistant to Salmonella infection, but neutropenic mice were not prot

141 proteins, is critical in such a response to salmonella infection, but the mechanism of how Ipaf is a

142 enia, there was a variable increase in total salmonella infection, but the relative splenic CFU of Sp

143 hoid tissues, their density increases during Salmonella infection, but the underlying molecular mecha

144 a critical cytokine in host defense against salmonella infections, but its role in phagocytic killin

145 stinct microbiota members prevent intestinal Salmonella infection by enhancing antibacterial IFNgamma

146 lagellin in the typhoid-like systemic murine Salmonella infection by measuring bacterial proliferatio

147 n of specific gut bacteria that protect from Salmonella infection by priming host IFN-gamma responses

148 Pase RalA, which we show is triggered during Salmonella infection by the translocated effector, SopE.

149 the role of B cells in acquired immunity to Salmonella infection by using gene-targeted B-cell-defic

150 ast to infection of macrophages by wild-type Salmonella, infection by the sopB deletion mutant had no

151 n the mechanism of DRA downregulation during Salmonella infection, by using murine epithelial enteroi

152 During experimental Salmonella infection, C3H/HeJ mice carrying a dominant-n

153 Salmonella infection can cause gastroenteritis in health

154 Together, these data suggest that low-dose Salmonella infection can evade flagellin-specific CD4 T

155 ture and phenotypic protocols for diagnosing Salmonella infections can be time-consuming.

156 pyrin-domain containing protein 3 (NLRP3) by Salmonella infection, CARD9 negatively regulates IL-1bet

157 Salmonella infections cause a disproportionately high nu

158 espond to bacterial and helminth infections: Salmonella infection caused an increase in the abundance

159 Systemic Salmonella infection commonly induces prolonged splenome

160 d innate IFN-gamma expression in response to Salmonella infection compared with SLC11A1(-) mice, whic

161 vertheless, the initial cellular response to Salmonella infections consists primarily of polymorphonu

162 Salmonella infections continue to be an important cause

163 Salmonella infections continue to cause substantial morb

164 mple, a subset of patients with a history of Salmonella infection develop reactive arthritis.

165 observed that in primary macrophages, during Salmonella infection, Elmo1 and Med31 specifically affec

166 that bacterial products (LPS), IL-6, RA, and Salmonella infection enhance the expression of the cathe

167 icrobial agent commonly used to treat severe Salmonella infections, especially in children.

168 mmune changes and lost resistance to enteric Salmonella infections even in the presence of T. musculi

169 These observations indicate that in Salmonella infection, flagellin plays a dominant role in

170 Salmonella infection for 1 h increased baseline ion tran

171 Here, we report that Salmonella infection generates directional electric fiel

172 These data demonstrate that Salmonella infection generates murine CD4+-T-cell respon

173 Of 52 821geocodable Salmonella infections (>96%), 48 111 (91.1%) were domest

174 Induction of iNOS in response to Salmonella infection has been demonstrated, but the bact

175 The mouse model of Salmonella infection has primarily been used as a model

176 Salmonella infections have been implicated in large-scal

177 Ceftriaxone-resistant Salmonella infections have recently been reported in the

178 ) are required for robust protection against Salmonella infection; however, the generation of this T

179 eractions in autophagy-dependent response to Salmonella infection, (ii) uncovering gene-environment i

180 During Salmonella infection, IL-35- and IL-10-producing B cells

181 testinal disease resulting from nontyphoidal Salmonella infection in an animal with an intact microbi

182 e show that a chronic systemic non-typhoidal Salmonella infection in an immunocompromised human patie

183 of the immune mechanisms protective against Salmonella infection in chickens has not been characteri

184 We examined data from all cases of Salmonella infection in FoodNet states during 1996-2006.

185 t cytokine response determine the outcome of Salmonella infection in genetically susceptible and resi

186 Here we use a model of auxotrophic Salmonella infection in germ-free mice to show that live

187 nomenon, we examined innate immunity to oral Salmonella infection in Hfe knockout (Hfe(-/-)) mice, a

188 virulence regulators facilitates persistent Salmonella infection in humans, by attenuating Salmonell

189 he innate and adaptive immune systems during Salmonella infection in mice and humans; however, the re

190 Since susceptibility to Salmonella infection in mice is strongly affected by the

191 roduction and a heightened susceptibility to Salmonella infection in mice undergoing withdrawal from

192 l epithelial and antigen-presenting cells to Salmonella infection in mice.

193 t flocks and eggs at the hatchery in case of Salmonella infection in parent flocks in the Danish poul

194 responses are required for the resolution of Salmonella infection in susceptible mice.

195 work, we also characterized the pathology of Salmonella infection in the ileum.

196 responses that are effective at controlling Salmonella infection in vivo.

197 ) have become a mainstay for treating severe Salmonella infections in adults.

198 agement, control, and prevention of invasive Salmonella infections in Africa.

199 ure-confirmed Campylobacter and nontyphoidal Salmonella infections in Australia, Canada, and the Unit

200 Despite the importance of Salmonella infections in human and animal health, the ta

201 w of these serovars are responsible for most Salmonella infections in humans and domestic animals.

202 ated with the reported national incidence of Salmonella infections in humans but were correlated with

203 Salmonella infections in infants under 3 mo are predomin

204 st antimicrobials used for treating invasive Salmonella infections in low- and middle-income countrie

205 t signs of enteritis or enterocolitis due to Salmonella infections in mice has limited the developmen

206 Salmonella infections in naturally susceptible mice grow

207 ated birds will enhance effective control of Salmonella infections in the poultry industry.

208 gnized outbreak of fluoroquinolone-resistant salmonella infections in the United States, which occurr

209 outcomes for patients with culture-confirmed Salmonella infection, in 9 states, each of which partici

210 This Salmonella infection induced both IL-12 and IFN-gamma in

211 Salmonella infection induces diarrhea by altering expres

212 In this study, we show that Salmonella infection induces the formation of an apoptos

213 Salmonella infection initiates caspase-8 proteolysis in

214 Based upon these findings, we propose that Salmonella infection involves an acid-dependent secretio

215 Salmonella infection is a globally important cause of ga

216 Enteric Salmonella infection is accompanied by inflammation and

217 at an important intestinal tract response to Salmonella infection is an enhanced production of SCF an

218 Salmonella infection is an increasingly important public

219 A critical early event in Salmonella infection is entry into intestinal epithelial

220 show that the T cell response to pathogenic Salmonella infection is localized to the gut-associated

221 An early event in Salmonella infection is the invasion of non-phagocytic i

222 Arp2/3 complex activation in the context of Salmonella infection is unclear.

223 Successful immunity against Salmonella infections is dependent on the generation of

224 Regional surveillance of Salmonella infections is necessary, especially with the

225 quinolones, which are used to treat invasive salmonella infections, is rare in the United States.

226 ells following antibiotic treatment of acute Salmonella infection limits mucosal remission.

227 Between 1996 and 2012, 45 outbreaks of human Salmonella infections linked to live poultry from mail-o

228 trogen species (RNS) produced in response to Salmonella infection lock persisters in growth arrest by

229 Our findings suggest that Salmonella infection may result in a shift from absorpti

230 We found that T cell clonotypes in a mouse Salmonella infection model span early activated CD4(+) T

231 Comparison between Salmonella infection models suggests how cooperation bet

232 hus, immunologists have frequently turned to Salmonella infection models to expand understanding of h

233 ed by LPS treatment in vitro as well as in a Salmonella infection mouse model in vivo.

234 An estimated 1.4 million salmonella infections occur annually in the United State

235 the characteristic inflammatory pathology of Salmonella infection occurs only in PPs and to a lesser

236 0 and the upregulation of this protein after Salmonella infection of eukaryotic cells, this mode of a

237 Upon Salmonella infection of macrophages, SipB was found in m

238 n plays an important antioxidant role during Salmonella infection of mammalian hosts.

239 ngs indicate that camp is not induced during Salmonella infection of MDMs nor is key to Salmonella in

240 for suppression of T cell activation during Salmonella infection of mice.

241 Salmonella infection of murine enteroid-derived monolaye

242 ) Salmonella serovars that are implicated in Salmonella infection of poultry.

243 ucosal inflammation that is triggered during Salmonella infection of the gastrointestinal and biliary

244 at the SseD protein is required for systemic Salmonella infection of the mouse, and we confirmed the

245 Caspase-3 activation was detected during Salmonella infection of THP-1 cells, but caspase-8 and c

246 Nontyphoidal Salmonella infections of children in tropical Africa.

247 his subspecies is responsible for almost all Salmonella infections of mammals and birds, these genes

248 nella enterica is responsible for almost all Salmonella infections of warm-blooded animals.

249 es following infection with Dam(+) or Dam(-) SALMONELLA: Infection of mice with Dam(+) Salmonella res

250 We monitored the impact of Salmonella infection on erythroid development and found

251 se findings emphasize the profound effect of Salmonella infection on erythroid development and sugges

252 foci within macrophages responding to either Salmonella infection or intoxication by Bacillus anthrac

253 e country-specific risk of travel-associated Salmonella infections (P = .001).

254 ciprofloxacin remains a common treatment for Salmonella infections, particularly in lower-resource se

255 In contrast, Salmonella infection produced high levels of lysosomal d

256 Salmonella infection profoundly affects host erythroid d

257 In summary, Salmonella infection rapidly increases Cox-2 expression

258 ples were obtained from patients with recent Salmonella infection, ReA, other SpA, and rheumatoid art

259 tion, the role of cell death during systemic Salmonella infection remained elusive.

260 ypes capable of producing IFN-gamma controls Salmonella infections remains unclear.

261 Salmonella infection resulted in upregulation of the sec

262 in casp-1(-/)- animals appears specific for Salmonella infection since these mice were susceptible t

263 appaB and mitogen-activated protein kinases, salmonella infection still activated caspase-1.

264 We found that although Salmonella infection strongly promotes the formation of

265 nly partially transferred protection against Salmonella infection, suggesting that minority species w

266 delayed NLRP3 inflammasome activation after Salmonella infection, suggesting that Salmonella may eva

267 tly, MMb conferred better protection against Salmonella infection than HMb.

268 , and they were more likely to clear chronic Salmonella infection than homozygotes.

269 -) mice were found to be more susceptible to Salmonella infection than WT mice, as evidenced by high

270 umbers of MDSCs and were more susceptible to Salmonella infection than young mice, suggesting a role

271 This work describes a mouse model of Salmonella infection that recapitulates several aspects

272 ount a multifaceted inflammasome response to Salmonella infection that ultimately restricts intracell

273 To resolve Salmonella infections, the stimulation of IL-12 and IFN-

274 he PmrA protein may limit the acute phase of Salmonella infection, thereby enhancing pathogen persist

275 the intestinal host defense against enteric Salmonella infections through Asc- and Il1r1-dependent T

276 During Salmonella infections, TLR-4 is activated, leading to in

277 extra- to intracellular environments during Salmonella infection triggers changes in Ag expression t

278 onitis, hepatic ischemia-reperfusion injury, Salmonella infection, uveitis and Sjogren's syndrome, PE

279 After Salmonella infection, VDR(-/-) mice had increased bacter

280 showed that this miRNA specifically inhibits Salmonella infection via modulation of endolysosomal tra

281 Here, using a mouse model of persistent Salmonella infection, we identify a host-protective role

282 yroptosis, necroptosis, and apoptosis during Salmonella infection, we infected mice and macrophages d

283 e the extent to which macrophages respond to Salmonella infection, we infected RAW 264.7 macrophages

284 Using a mouse model of systemic Salmonella infection, we observed that only a lack of al

285 In order to identify key players involved in Salmonella infection, we performed a global host phospho

286 ts with antimicrobial-resistant nontyphoidal Salmonella infection were more likely to have bloodstrea

287 rugs that are not appropriate for therapy of Salmonella infections were tested and reported by 136 (9

288 RAW264.7 macrophages are more responsive to Salmonella infection when treated with thapsigargin but

289 g human-relevant differences in nontyphoidal Salmonella infections, whereas differentiated human THP-

290 tilized both the traditional model of murine Salmonella infection, wherein low-dose oral infection of

291 t PedsCom mice retain high susceptibility to Salmonella infection, which is characteristic of young m

292 bility of CD4(+) T cells during a persistent Salmonella infection, which is typical of persistent pha

293 ntaining vacuoles and host mitochondria upon Salmonella infection, which was significantly impaired i

294 ved understanding of the biology of invasive Salmonella infection will facilitate the development of

295 m mathematical models of in vivo dynamics of Salmonella infections with experimental observation of b

296 We found that during Salmonella infections with three avirulent strains, MHC

297 lium and lamina propria up to 2 months after Salmonella infection, with an abundant presence of macro

298 ical consequences of NO production following Salmonella infection, with NO being necessary for host d

299 oidal Salmonella serotype which causes human Salmonella infections worldwide.

300 are essential mediators of immunity against Salmonella infection, yet it is not clear whether target