ライフサイエンスコーパス: Schiff base

1 favor of the oxoenamine tautomer (protonated Schiff base).

2 oplasmic half-channel, located 15 A from the Schiff base.

3 as the internal proton donor to the retinal Schiff base.

4 changes dramatically with protonation of the Schiff base.

5 (PLP), apparently without a solvent-exposed Schiff base.

6 bing rhodopsins bind an unprotonated retinal Schiff base.

7 derivative, bound to a protein (opsin) via a Schiff base.

8 nal and form a covalent bond as a protonated Schiff base.

9 r proton transfer in the external PLP-L-dopa Schiff base.

10 bly being a primary proton acceptor from the Schiff base.

11 proton-conduction pathway from Asp96 to the Schiff base.

12 side chain of Tyr57 and with the C15H of the Schiff base.

13 tate as an alternate proton acceptor for the Schiff base.

14 group (PRG) on the extracellular side of the Schiff base.

15 gem-diol, 2) aldehyde, 3) hemiaminal, and 4) Schiff base.

16 as an internal aldimine with a deprotonated Schiff base.

17 ate 3 that is in equilibrium with the cyclic Schiff base.

18 ted at the edge of PLP opposite the reactive Schiff base.

19 channel occurs prior to deprotonation of the Schiff base.

20 aldehyde to form a hydrogel in situ based on Schiff base 2 as a low-molecular-weight gelator (LMWG).

21 ium(II) and tin(II) by using the substituted Schiff base 2,6-diacetylpyridinebis(2,6-diisopropylanil)

22 tion of sebacic acid, 1,3-propanediol, and a Schiff-base (2-[[(2-hydroxyphenyl) methylene]amino]-1,3-

23 scent molecular rotors of boron derived from Schiff bases: (2,4,8,10-tetra-tert-butyl-6-phenyldibenzo

24 The N-alkylated indanylidenepyrroline (NAIP) Schiff base 3 is an unnatural alpha-amino acid precursor

25 neC backbone of all-trans retinal protonated Schiff base accelerates the electronic decay in solution

26 ty of the immobilised polymer generated with Schiff-base activation and immobilisation scheme.

27 y in this system is provided by a protonated Schiff base adduct of retinaldehyde and taurine (A1-taur

28 protease through the formation of a covalent Schiff base adduct of the pBzF residue with the epsilon-

29 aracteristics and they were more stable than Schiff base adducts at 60 degrees C.

30 tion of an isocyanide to a hydrazine derived Schiff base affords unique six-membered pyridotriazine s

31 n nanotubes/BaFe12O19-chitosan (MCNTs/BF-CS) Schiff base Ag (I) complex composites were synthesized s

32 The results show that the BF-CS Schiff base Ag (I) complexes are embedded into MCNT netw

33 l side chains were also accessed via glycine Schiff base alkylation, further increasing the scope of

34 rs with salicylaldehyde to the corresponding Schiff base allows analysis of the dr based on a change

35 ges in the K-state propagating away from the Schiff base along the polyene chain.

36 est results were obtained using a tridentate Schiff base aluminum(III) Lewis acidic complex, 1H-1,2,3

37 UV-absorbing photoreceptor with deprotonated Schiff base and allowed reconstitution into native-like

38 by formation of a direct H-bond between the Schiff base and Asn87.

39 crements of 54 and 134 amu, corresponding to Schiff base and dihydropyridine (DHP)-type adducts, resp

40 Specifically, interconversion of Schiff base and enamine intermediates, formed covalently

41 ses strain in the Lys pyridoxal 5'-phosphate Schiff base and increases the pK(a), resulting in proton

42 the connectivity of the active site once the Schiff base and its counterion are neutralized by proton

43 observe a deuterium equidistant between the Schiff base and the C-terminal carboxylate of the substr

44 the late M- (M2) with a deprotonated retinal Schiff base and the consecutive green-absorbing N-state

45 n involves both hydrolysis of the protonated Schiff base and thermal isomerization of 11-cis to all-t

46 f the carbinolamine intermediate to give the Schiff base and to function as a general acid/base.

47 ct asymmetric aldol reaction between glycine Schiff bases and aldehydes is reported.

48 hat DOPAL interacts with aS via formation of Schiff-base and Michael-addition adducts with Lys residu

49 ied interaction network between chromophore, Schiff base, and counterion complex explaining the alter

50 ex counterion to the protonated retinylidene Schiff base, and neutralization of the negatively charge

51 study, including a reaction intermediate, 2 Schiff bases, and 28 bis- or tris(pyrazol-3(4)-yl)methan

52 Treatment of alpha-silylaryl triflates, Schiff bases, and alkynes generated polysubstituted pyrr

53 n and the deprotonation/reprotonation of the Schiff base, are coupled to the channel-opening mechanis

54 adily available halogen sources and a simple Schiff base as the chiral catalyst.

55 erived from a new water-soluble pentadentate Schiff base backbone ligand has been prepared and charac

56 The Schiff base becomes protonated in the transition to Meta

57 Asparagine reacted with fructose to form a Schiff base before decarboxylation to produce acrylamide

58 ing sugars react with asparagine to form the Schiff base before decarboxylation, to generate acrylami

59 the bound product reveals the presence of a Schiff base between C-4' of the PLP cofactor and the ami

60 which is consistent with the formation of a Schiff base between Top1 and the ring open aldehyde form

61 cally isomerizes the retinylidene protonated Schiff base both thermally and photochemically.

62 omerization and dark state hydrolysis of the Schiff base by 1-2 orders of magnitude.

63 rt cycle includes protonation of the retinal Schiff base by Asp96 (M-->N reaction) and reprotonation

64 es of both the hemiaminal and the dehydrated Schiff base can be observed by CEST NMR, even when their

65 Here we show that by localizing manganese-Schiff base catalysts at the oil droplet-water interface

66 t the ability of substrates to form covalent Schiff base catalytic intermediates and to initiate chem

67 ile the cytoplasmic part comprises a cavity (Schiff base cavity [SBC]) surrounded by charged amino ac

68 nks) revealed that the reaction proceeds via Schiff base chemistry facilitated by lysine residues.

69 lar surface coverage confirm the efficacy of Schiff base chemistry, at least with the terephthalaldeh

70 The reductive half-reaction proceeds via Schiff base chemistry, in which the primary amine substr

71 Recently, the Schiff-base chemistry or dynamic imine-chemistry has bee

72 nd synthetic strategies toward COFs based on Schiff-base chemistry, collects and rationalizes their p

73 In dark-adapted ChR2, the protonated retinal Schiff base chromophore (RSBH(+)) adopts an all-trans,C=

74 hysical properties of the retinal-protonated Schiff base chromophore in solution.

75 itory action of a biologically inert Co(III) Schiff base (Co(III)-sb) complex.

76 e activation of a biologically inert Co(III) Schiff base [Co(III)-SB] complex to its protein inhibito

77 trate that neither the oligo, or the Co(III) Schiff base complex alone, are sufficient for inactivati

78 A Co(III) Schiff base complex modified with a 17-bp DNA sequence i

79 and characterization of a novel cobalt(III) Schiff base complex with methylamine axial ligands, and

80 ed pyrolysis of a series of heterobimetallic Schiff base complexes ensures a rigorous control of the

81 ation of bithiophene-substituted cadmium(II) Schiff base complexes forms thin conducting metallopolym

82 hemoglobin amino groups to produce unstable Schiff base complexes that can dissociate or rearrange t

83 became trapped by MR1 as reversible covalent Schiff base complexes.

84 ohydride reduction confirmed the presence of Schiff base complexes.

85 etization), and Hc (coercivity) of the BF-CS Schiff base composites reach 1.908 S cm(-1), 28.20 emu g

86 edominance of intermediate MRPs, such as the Schiff base compounds.

87 For pi-conjugated COFs, the Schiff base condensation of aldehydes and amines is the

88 by employing the solvothermal aldehyde-amine Schiff base condensation reaction.

89 Schiff-base condensation between an amine and an aldehyd

90 In view of such features, Schiff base condensations are thermodynamically controll

91 Metal template Schiff base condensations have produced multinuclear met

92 tions with imine nitrogen atoms, can address Schiff base condensations of even more complex molecular

93 transfer between the zwitterionic protonated Schiff base configuration and the neutral hydroxyimine t

94 The transient Schiff base conjugate that the primary amine of taurine

95 ccumulation of excess 11-cis-retinal and its Schiff-base conjugate and the formation of toxic bisreti

96 inylidene-phosphatidylethanolamine (PE), the Schiff-base conjugate of 11-cis-retinal and PE, from the

97 we detected the presence of emixustat-atRAL Schiff base conjugates, indicating that emixustat also a

98 , we show that 5fC bases in DNA readily form Schiff-base conjugates with Lys side chains of nuclear p

99 ns in the HtrI subunit of the complex on SRI Schiff base connectivity indicate that the two proteins

100 f the SRI-HtrI attractant conformer causes a Schiff base connectivity switch from inwardly connected

101 Mutation of the primary Schiff base counterion (VCOP(D108A)) produced a pigment

102 ncluding the D121-H87 cluster of the retinal Schiff base counterion and a glutamate at position 132 t

103 ide pH range and interacts directly with the Schiff base counterion Asp-97; and (ii) photoisomerizati

104 lier observations that neutralization of the Schiff base counterion, Asp97, does not block the format

105 The unusual charge neutrality of both Schiff base counterions in the P2 (380) conducting state

106 of an abasic site by a mechanism involving a Schiff-base covalent intermediate with the abasic site.

107 adipic and gamma-glutamic semialdehydes) and Schiff base cross-links.

108 the amyloid fibril through the formation of Schiff bases, cross-linking the fibrils, which may preve

109 or other residues slows reprotonation of the Schiff base (decay of the M intermediate) by more than 2

110 re model compound 11-cis-retinyl-propylamine Schiff base demonstrate the direct isomerization of visu

111 the protein sequence controls the extent of Schiff base deprotonation and accumulation of intermedia

112 and is described by a multisquare model with Schiff base deprotonation at the lumirhodopsin I interme

113 I-Lumi II process that immediately precedes Schiff base deprotonation in the activation of rhodopsin

114 c scheme, the human rhodopsin exhibited more Schiff base deprotonation than bovine rhodopsin, which c

115 absorbance spectrum at earlier times or the Schiff base deprotonation-reprotonation which occurs dur

116 e nanodisc environment leading to an earlier Schiff base deprotonation.

117 and, in the presence of O(2) , both types of Schiff base DOPAL-peptide intermediates rapidly react wi

118 ollowing reduction of the retinal protonated Schiff base double bond.

119 and its ability to accept a proton from the Schiff base during the photocycle.

120 The formation of cross-links (assessed as Schiff bases) during freezing and the subsequent process

121 of retinal model compounds reveals that the Schiff base environment is polar.

122 yme showed L-methionine bound in an external Schiff base (ESB) linkage to PLP as the enzyme was isola

123 s reaction proceeds via in situ formation of Schiff-base followed by base mediated alkylation with ph

124 rhodopsins, which bind a protonated retinal Schiff base for light absorption, UV-absorbing rhodopsin

125 talytic cycle is facilitated by a protonated Schiff base form of the holoenzyme in which the linking

126 he equilibrium in favor of the EC-accessible Schiff base form, and suppressor mutations shift the equ

127 he equilibrium back toward the CP-accessible Schiff base form, restoring the wild-type phenotype.

128 mpounds that transiently sequester atRAL via Schiff base formation ameliorate retinal degeneration.

129 for all steps of the mechanism, most notably Schiff base formation and hydrolysis.

130 rimary alkoxides and diaminopyrimidines with Schiff base formation and subsequent annulation in the p

131 stable 1,3-thiazines, whereas the reversible Schiff base formation between aldehydes and amino groups

132 Schiff base formation between Lys99 and the imine of the

133 ation of the ion/ion intermediate results in Schiff base formation generated via reaction between a p

134 te lysine residue that is initially used for Schiff base formation in the internal aldimine and later

135 tent of protein oxidation (carbonylation and Schiff base formation) and their sensory profile (quanti

136 s binding to 8-oxoG-containing DNA, promotes Schiff base formation, and stimulates its glycosylase an

137 When combined with amino acids they undergo Schiff base formation, decarboxylation and alpha-aminoke

138 , (ii) dynamic covalent cross-linking (e.g., Schiff base formation, disulfide formation, reversible D

139 idues is poised to activate the substrate by Schiff base formation, promote mechanistically important

140 trategically located -COOH which accelerates Schiff base formation.

141 active site does not appreciably change upon Schiff base formation.

142 Schiff-base formation between Abeta and the aldehyde-bea

143 Schiff-base formation between DOB and histone proteins i

144 king structures are determined by reversible Schiff-base formation, before irreversible Wittig olefin

145 midoxime acts as an internal general acid in Schiff-base formation.

146 ise to water loss in conjunction with imine (Schiff base) formation.

147 ctions of TCNQF (-) radicals (H2valpn is the Schiff base from the condensation of o-vanillin with 1,3

148 Here, using as model Schiff bases generated from salicylaldehydes and TRIS in

149 ox-mediated coupling of benzylic ethers with Schiff bases has been accomplished.

150 certain cases, however, compounds other than Schiff bases have been reported to result from such reac

151 nd cone visual pigments undergoes reversible Schiff base hydrolysis and dissociation following photob

152 Accelerating Schiff base hydrolysis and subsequent ATR dissociation,

153 not from inherent differences in the rate of Schiff base hydrolysis but rather from differences in th

154 e visual pigments is necessary for efficient Schiff base hydrolysis.

155 polarized in a manner that would facilitate Schiff base hydrolysis.

156 ecedes the deprotonation of the retinylidene Schiff base (i.e., formation of an M intermediate).

157 n screening using either disulfide bridge or Schiff base imine immobilization chemistries on plasmach

158 nes), forming either hemiaminal (+148 Da) or Schiff base (imine, +130 Da) products.

159 embrane voltage modulates protonation of the Schiff base in a 13-cis photocycle intermediate (M right

160 d from hydroxyl-bearing amino acids near the Schiff base in different visual pigments: at site 292 (A

161 refore suggest that the reprotonation of the Schiff base in ESR is preceded by transient protonation

162 blot, staining by Coomassie or Periodic Acid-Schiff base in gels, and with proteomics.

163 The (15)N chemical shift of the Schiff base in K indicates that contact has been lost wi

164 rs to be capable of stabilizing a protonated Schiff base in Meta III, but not of constraining the rec

165 energetics and the protonation state of the Schiff base in retinal, the covalently bound ligand resp

166 nts of proton transfer from the retinylidene Schiff base in several channelrhodopsin variants express

167 of the internal proton donor to the retinal Schiff base in the light-driven proton pump of Exiguobac

168 g the intermediate Opsin-derived, protonated Schiff base in the visual cycle with simple polarized al

169 photoisomerization of the retinal protonated Schiff-base in bacteriorhodopsin, isorhodopsin and rhodo

170 eins was confirmed by NaBH4 reduction of the Schiff base intermediate and kinetics studies.

171 rupture of the C1'-O4' bond, resulting in a Schiff base intermediate at the N-glycosidic bond.

172 the pyrimidine ring is maintained, while the Schiff base intermediate is preferred if the C5 horizont

173 occurs before a conformational change of the Schiff base intermediate toward a cyclic structure.

174 proline as the nucleophile, MmuNeil3 forms a Schiff base intermediate via its N-terminal valine.

175 Such a Schiff base intermediate was trapped and characterized b

176 Strand scission proceeds via a Schiff base intermediate, but the DNA-protein cross-link

177 dently of divalent cation and proceeds via a Schiff base intermediate, indicating that it occurs via

178 avage of beta-hydroxy-ketones via a covalent Schiff base intermediate.

179 generally unstable, hydrated and dehydrated, Schiff base intermediates that often are unobservable by

180 tive exchange kinetics between reactants and Schiff base intermediates, explaining why the Schiff bas

181 for the formation/hydrolysis of the covalent Schiff base intermediates, whereas the other conformatio

182 arbonyl of TPQ, forming a series of covalent Schiff base intermediates.

183 When the mass ratio of MCNTs and BF-CS Schiff base is 0.95:1, the conductivity, Ms (saturation

184 e capable of binding retinal as a protonated Schiff base is described.

185 the proton dissociation from the protonated Schiff base is not affected, the rate of its reprotonati

186 the hydroxyimine form of the PLP(H+)-L-dopa Schiff base is predicted to be the major isomer with a r

187 romophore covalently linked to Lys(296) by a Schiff base is subsequently hydrolyzed, but little is kn

188 ntered radical character of an excited state Schiff base is unique, requiring only violet light in th

189 kes place shortly after deprotonation of the Schiff base (L-to-M transition) and results in an increa

190 rption spectrum consistent with a protonated Schiff base (lambda(max) = 420 nm).

191 vitamin B12 samples after complexing with a Schiff base ligand.

192 Schiff base ligands have long been successfully employed

193 One of the most widely used Schiff base ligands, the "salen" ligand, has been extens

194 plex has an outwardly connected retinylidene Schiff base like the repellent signaling forms of the SR

195 g an RGR variant, K255A, we confirmed that a Schiff base linkage at Lys-255 is critical for substrate

196 cis-retinal and hydrolysis of the protonated Schiff base linkage between the 11-cis-retinal chromopho

197 )N NMR chemical shift measurements of such a Schiff base linkage in the resting holoenzyme form, the

198 in the product the enzyme no longer makes a Schiff base linkage to the pyridoxal 5'-phosphate (PLP)

199 forms a covalent bond with retinal through a Schiff base linkage.

200 ter-mediated H-bonding interactions with the Schiff base linkage.

201 ly bound to the protein through a protonated Schiff base linkage.

202 is-retinal (11CR), by a covalent, protonated Schiff base linkage.

203 t Arch variants, the pK(a) of the protonated Schiff-base linkage to retinal is near neutral pH, a use

204 l salt bridge between the retinal protonated Schiff base linked to H7 and Glu113 on H3 is one of the

205 on of Phe-86 that converted the unprotonated Schiff base-linked 11-cis-retinal to a protonated form.

206 n the retinal binding pocket of rhodopsin, a Schiff base links the retinal ligand covalently to the L

207 methyl-4-carboxy-2,2'-bipyridine, and L is a Schiff base macrocycle derived from 2,6-diformyl-4-methy

208 inuclear magnesium complex of a polypyrrolic Schiff base macrocycle results in the formation of a new

209 arth trication in a binucleating polypyrrole Schiff-base macrocycle (Pacman) and bridged through a ur

210 , however our results suggest an alternative Schiff base mechanism which may be responsible for the r

211 We suggest a mechanism where Schiff base-mediated deimination forms DMQ(6) quinone, t

212 HDL was immobilized by the Schiff base method onto silica and gave HPAC columns wit

213 Furthermore, Schiff-base-modified peptides exhibit on average a 20% i

214 lished by replacing the rapidly hydrolyzable Schiff-base moiety of first-generation members with a cy

215 h the internal aldimine is protonated on the Schiff base N.

216 The influence of a Schiff base namely N,N'-(pyridine-2,6-diyl)bis(1-(4-meth

217 omophore and the (15)N chemical shift of the Schiff base nitrogen in the active metarhodopsin II inte

218 between positions C10 and C15 as well as the Schiff base nitrogen in the ground state in comparison t

219 ce experiments confirm the assignment of the Schiff base nitrogen, and additional (13)C, (15)N, and (

220 chiff base intermediates, explaining why the Schiff base NMR signals are rarely observed.

221 Replacing the n-butylamine Schiff base normally chosen to mimic the saturated linka

222 new channelrhodopsin mechanism, in which the Schiff base not only controls gating, but also serves as

223 fluctuations in the protonation state of the Schiff base occur prior to forming the activated MII sta

224 ed bond-length alternation of the protonated Schiff base of 11-cis-retinal chromophore, induced by N8

225 e in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL).

226 0) energy surfaces (Phi(CI)) of a protonated Schiff base of all-trans retinal in protic and aprotic s

227 ly converted to an agonist, the unprotonated Schiff base of all-trans retinal, upon light activation.

228 nfirmed the formations of Michael adduct and Schiff base of HMF with amino acids.

229 lidene-pyrroline chromophore that mimics the Schiff base of rhodopsin and can be used to introduce li

230 tem, were synthesized from the corresponding Schiff bases of O-perbenzoylated (gluculopyranosylamine)

231 been exploited for over 150 years to produce Schiff bases, one of the most popular classes of compoun

232 e conclude that Lumi II (the last protonated Schiff base photointermediate under physiological condit

233 the complex [(UO2 )(THF)(H2 L)] (L="Pacman" Schiff-base polypyrrolic macrocycle), is found and expla

234 ly conjugated oligomers of secondary imines (Schiff bases) present at relatively low concentrations.

235 Heterobis imine Schiff base probe L is able to discriminate geometrical

236 nary support increased with each step of the Schiff-base process: poly(Ethylene glycol Dimethacrylate

237 lision-induced dissociation (CID) produces a Schiff base product anion.

238 )methane derivatives instead of the expected Schiff base products.

239 wever, the rapid and reversible formation of Schiff base prohibits formation of alternative products,

240 that occupy the positions of the chromophore Schiff base proton acceptor and donor, a hallmark of rho

241 3) (Asp(253) in CrChR2) receives the retinal Schiff base proton during M-state formation.

242 ay observed in the mutants suggests that the Schiff base proton is one of the displaced charges.

243 ) photoisomerization-induced transfer of the Schiff base proton to the Asp-97 counterion disrupts its

244 the mutation of which to Glu produced early Schiff base proton transfer and strongly inhibited chann

245 hodopsin acts as the primary acceptor of the Schiff-base proton in low-efficiency channelrhodopsins.

246 onfiguration that maintains the retinylidene Schiff base protonated when the channel is open.

247 to approximately 40 kcal/mol for protonated Schiff base (PSB) chromophore in rhodopsin.

248 11-cis retinyl chromophore with a protonated Schiff-base (PSB11), UV pigments uniquely contain an unp

249 r the synthesis of a library of 442 Ru-arene Schiff-base (RAS) complexes.

250 ans-cinnamaldehyde were bound to chitosan by Schiff base reaction and reductive amination.

251 p-Azo and Tp-Stb) were synthesized using the Schiff base reaction between triformylphloroglucinol (Tp

252 etic strategy that regulates the sequence of Schiff base reaction via weak secondary interactions.

253 for immobilization of DNA probes through the Schiff base reaction.

254 ly immobilized to the host IL through simple Schiff base reaction.

255 Syntheses of these COFs were done by the Schiff base reactions of 1,3,5-triformylphloroglucinol (

256 t M-states have been observed reflecting the Schiff base reorientation after the deprotonation step.

257 gen of the PLP and the imino nitrogen of the Schiff base, respectively.

258 m chemical models of three distinct types of Schiff base rotary motors.

259 photoisomerization of the retinal protonated Schiff base (RPSB) chromophore.

260 ton, its chromophore, the retinal protonated Schiff base (RPSB), isomerizes from its native all-trans

261 ge separation between the protonated retinal Schiff base (RSBH(+)) and its counterion complex.

262 es (MWCNT), chitosan and a novel synthesized Schiff base (SB) (TiO2/MWCNT/CHIT/SB) on the surface of

263 of 11-cis-retinal followed by hydrolysis of Schiff base (SB) and 2) hydrolysis of SB in dark state r

264 A hydrazone based Schiff base (SB) has been synthesized and investigated f

265 donor, respectively, of the photoactive site Schiff base (SB) proton.

266 he retinyl chromophore and hydrolysis of the Schiff base (SB) through which the retinyl chromophore i

267 es E90, E123, D253, N258, and the protonated Schiff base (SBH), as well as nearby residues K93, T127,

268 embly of paramagnetic Cu(2) complexes with a Schiff base scaffold possessing extended electron deloca

269 carboxylate anion on the alpha-carbon of the Schiff base stabilizes the zwitterions and shifts the eq

270 oxidised to alpha-aminoadipic acid and form Schiff bases structures.

271 imple model where backbone modifications and Schiff base substituents control barrier heights on the

272 Acid catalysis, which is often employed in Schiff base synthesis, radically changes the course of r

273 rtate 253 accepts the proton released by the Schiff base (t(1/2) = 10 mus), with the latter being rep

274 that deprotonation and reprotonation of the Schiff base take place on the same (outer) side of the m

275 ilibrium between the phenolic and protonated Schiff base tautomeric forms of this intermediate.

276 r molecule, would trigger the formation of a Schiff base that can undergo further dehydration reactio

277 achieved by preventing reprotonation of the Schiff base through a mutation of the primary proton don

278 It involves the formation of a Schiff base through a reaction between the ketone and th

279 through 1,2-elimination, their alkylation by Schiff bases through 1,2-addition, 1,4-intramolecular pr

280 ing the primary phototransition and from the Schiff base to Glu-169 during P2 (380) formation.

281 s the pK(a), resulting in protonation of the Schiff base to initiate transaldimination.

282 s the light-induced proton transfer from the Schiff base to its counterion Asp-97 during the photocyc

283 e in ADC nor norspermidine in CANSDC, form a Schiff base to pyridoxal 5'-phosphate, suggesting that t

284 st, reductive conditions were applied to the Schiff base to yield secondary amine 3, which is also a

285 connection of their retinylidene protonated Schiff bases to the outwardly located periplasmic side a

286 rtate residue, the counterion to the retinal Schiff base, to a histidine.

287 Recently, we reported a Mn(III) Schiff base-type complex, Mn((tbu)dhbpy)Cl, where 6,6'-d

288 The urea analysis relied on the formation of Schiff base under acidic conditions.

289 ostatic effects surrounding the unprotonated Schiff base (USB) retinyl chromophore in the UV pigment.

290 UV pigments uniquely contain an unprotonated Schiff-base (USB11).

291 and amino acid side chains in the immediate Schiff base vicinity are very well conserved.

292 The pKa of the retinylidene protonated Schiff base was modulated from 2.4 to 8.1, giving rise t

293 mining step of the process is formation of a Schiff base, which is followed by rapid intramolecular r

294 actions with His910 and Phe889, an essential Schiff base with Lys907 and a hydrogen bond with Tyr892.

295 s selectivity by forming an unusually stable Schiff base with lysine 907 in the IRE1 endonuclease dom

296 Neither ligand forms a Schiff base with MR1 molecules; both are nevertheless se

297 VitB antigens reach this location and form a Schiff base with MR1, triggering a 'molecular switch' th

298 PLP forms a Schiff base with the -amino group of a lysine residue of

299 ed active site lysine residue, which forms a Schiff base with the PLP cofactor.

300 factors and does not form a protein-mediated Schiff base with the substrate, unlike most aldolases.