ライフサイエンスコーパス: Schiff

1 Schiff base ligands have long been successfully employed

2 Schiff-base condensation between an amine and an aldehyd

3 Schiff-base formation between DOB and histone proteins i

4 study, including a reaction intermediate, 2 Schiff bases, and 28 bis- or tris(pyrazol-3(4)-yl)methan

5 gem-diol, 2) aldehyde, 3) hemiaminal, and 4) Schiff base.

6 muli using a visual analog scale (VAS) and a Schiff scale.

7 tion of sebacic acid, 1,3-propanediol, and a Schiff-base (2-[[(2-hydroxyphenyl) methylene]amino]-1,3-

8 romophore covalently linked to Lys(296) by a Schiff base is subsequently hydrolyzed, but little is kn

9 Asparagine reacted with fructose to form a Schiff base before decarboxylation to produce acrylamide

10 VitB antigens reach this location and form a Schiff base with MR1, triggering a 'molecular switch' th

11 Neither ligand forms a Schiff base with MR1 molecules; both are nevertheless se

12 PLP forms a Schiff base with the -amino group of a lysine residue of

13 rupture of the C1'-O4' bond, resulting in a Schiff base intermediate at the N-glycosidic bond.

14 of an abasic site by a mechanism involving a Schiff-base covalent intermediate with the abasic site.

15 The influence of a Schiff base namely N,N'-(pyridine-2,6-diyl)bis(1-(4-meth

16 r molecule, would trigger the formation of a Schiff base that can undergo further dehydration reactio

17 It involves the formation of a Schiff base through a reaction between the ketone and th

18 mining step of the process is formation of a Schiff base, which is followed by rapid intramolecular r

19 lision-induced dissociation (CID) produces a Schiff base product anion.

20 n the retinal binding pocket of rhodopsin, a Schiff base links the retinal ligand covalently to the L

21 Such a Schiff base intermediate was trapped and characterized b

22 )N NMR chemical shift measurements of such a Schiff base linkage in the resting holoenzyme form, the

23 g an RGR variant, K255A, we confirmed that a Schiff base linkage at Lys-255 is critical for substrate

24 forms a covalent bond with retinal through a Schiff base linkage.

25 Strand scission proceeds via a Schiff base intermediate, but the DNA-protein cross-link

26 derivative, bound to a protein (opsin) via a Schiff base.

27 vitamin B12 samples after complexing with a Schiff base ligand.

28 embly of paramagnetic Cu(2) complexes with a Schiff base scaffold possessing extended electron deloca

29 trategically located -COOH which accelerates Schiff base formation.

30 Accelerating Schiff base hydrolysis and subsequent ATR dissociation,

31 and non-SS ATD was stained with period acid Schiff.

32 en stores were evaluated using periodic acid Schiff (PAS) stains.

33 t(W/Wv) mice were stained with periodic acid Schiff (PAS) to detect glycogen.

34 , and surgical excision showed Periodic acid Schiff (PAS)-positive eosinophilic structures inside mac

35 Periodic Acid Schiff and alkaline phosphatase staining revealed subapi

36 sal biopsies were stained with Periodic Acid Schiff-Alcian Blue, and GCD was measured as number of go

37 cell density was evaluated in periodic acid Schiff-stained conjunctival sections.

38 with hematoxylin and eosin and periodic acid Schiff.

39 cell density was counted after Periodic-acid Schiff staining.

40 roxide (KOH) stain followed by periodic acid-Schiff (PAS) evaluation if KOH testing is negative, and

41 Cassava samples stained with Periodic Acid-Schiff (PAS) highlighted the presence of starch and cell

42 tained with hematoxylin-eosin, periodic acid-Schiff (PAS) reaction, and Masson trichrome method.

43 x specimens were reexamined by periodic acid-Schiff (PAS) staining and PCR to identify undiagnosed am

44 elated with hematoxylin-eosin, periodic acid-Schiff (PAS), and mucicarmine-stained preparations.

45 itive for CK7, CEA, as well as periodic acid-Schiff (PAS), whereas negative for CK5/6, CK34betaE12, C

46 e observed significantly fewer periodic acid-Schiff (PAS)-stained intestinal goblet cells and less mu

47 y tissue sections stained with periodic acid-Schiff (PAS).

48 Periodic acid-Schiff and immunohistochemical staining revealed mucous

49 tandard hematoxylin and eosin, periodic acid-Schiff and silver methenamine, and picrosirius red stain

50 blot, staining by Coomassie or Periodic Acid-Schiff base in gels, and with proteomics.

51 th L. interrogans Histological periodic acid-Schiff D staining of infected kidney showed interstitial

52 epitheliopathy and Alcian blue/periodic acid-Schiff histochemical analysis to characterize goblet cel

53 Periodic acid-Schiff loops and CD11b(+) macrophages within the tumor s

54 lumina and Bowman spaces; and Periodic Acid-Schiff positive structures.

55 ormed on hematoxylin-eosin and periodic acid-Schiff sections.

56 reous biopsy with cytospin and periodic acid-Schiff stain for hyphae was the most sensitive method fo

57 njunctiva of the right eye for periodic acid-Schiff staining and from the left eye for MUC5AC mucin i

58 rmed in this category included Periodic Acid-Schiff staining for fungi, PCR analysis for toxoplasmosi

59 ocyte markers gene expression, Periodic Acid-Schiff staining for glycogen storage, ELISA for albumin

60 ion was determined by means of periodic acid-Schiff staining of lung sections, Western blot analysis

61 blet cell hyperplasia by using periodic acid-Schiff staining, and cytokine and chemokine levels by pe

62 were undetectable on standard periodic acid-Schiff staining, even though only a single histologic se

63 and hematoxylin and eosin and periodic acid-Schiff staining, respectively.

64 dients in glycogen storage via periodic acid-Schiff staining, urea production via carbamoyl phosphata

65 ed using hematoxylin-eosin and periodic acid-Schiff stains.

66 technique using trichrome and periodic acid-Schiff subtraction morphometry; the other two methods in

67 n perfusates was quantified by periodic acid-Schiff's base dot-blot assay, using purified pig gastric

68 tology (hematoxylin and eosin, periodic acid-Schiff) and terminal deoxynucleotidyl transferase dUTP n

69 aining with hematoxylin-eosin, periodic acid-Schiff, and Gram stain.

70 oscopy, hematoxylin and eosin, periodic acid-Schiff, Congo red, and light microscopy.

71 amined with hematoxylin-eosin, periodic acid-Schiff, Masson trichrome, or reticulin stains.

72 with hematoxylin and eosin and periodic acid-Schiff, visualized by means of electron microscopy, and

73 Glycogen determination and periodic acid-Schiff-diastase staining were used to analyze glycogen a

74 Occlusion of sweat ducts with periodic acid-Schiff-positive and Congo red-positive material was note

75 cy, 7 had BAL fluid containing periodic acid-Schiff-positive surfactant-like material with macrophage

76 elying solely on visualizing a periodic acid-Schiff-positive vacuolar myopathy to identify late-onset

77 Hyalinized periodic acid-Schiff-positive vessels were widely separated.

78 e of being densely loaded with periodic acid-Schiff-positive, diastase-resistant granules, resembling

79 e for accurate segmentation of periodic acid-Schiff-stained kidney tissue from healthy mice and five

80 digital whole-slide images of periodic acid-Schiff-stained kidneys from various species and renal di

81 o analyze histologic images of periodic acid-Schiff-stained renal sections from a cohort of mice with

82 he ducts that was positive for periodic acid-Schiff.

83 tions with imine nitrogen atoms, can address Schiff base condensations of even more complex molecular

84 , however our results suggest an alternative Schiff base mechanism which may be responsible for the r

85 by employing the solvothermal aldehyde-amine Schiff base condensation reaction.

86 nfirmed the formations of Michael adduct and Schiff base of HMF with amino acids.

87 tent of protein oxidation (carbonylation and Schiff base formation) and their sensory profile (quanti

88 imple model where backbone modifications and Schiff base substituents control barrier heights on the

89 tive exchange kinetics between reactants and Schiff base intermediates, explaining why the Schiff bas

90 adipic and gamma-glutamic semialdehydes) and Schiff base cross-links.

91 r the synthesis of a library of 442 Ru-arene Schiff-base (RAS) complexes.

92 The formation of cross-links (assessed as Schiff bases) during freezing and the subsequent process

93 we detected the presence of emixustat-atRAL Schiff base conjugates, indicating that emixustat also a

94 A hydrazone based Schiff base (SB) has been synthesized and investigated f

95 The unusual charge neutrality of both Schiff base counterions in the P2 (380) conducting state

96 Replacing the n-butylamine Schiff base normally chosen to mimic the saturated linka

97 through 1,2-elimination, their alkylation by Schiff bases through 1,2-addition, 1,4-intramolecular pr

98 ans-cinnamaldehyde were bound to chitosan by Schiff base reaction and reductive amination.

99 idues is poised to activate the substrate by Schiff base formation, promote mechanistically important

100 ile the cytoplasmic part comprises a cavity (Schiff base cavity [SBC]) surrounded by charged amino ac

101 that occupy the positions of the chromophore Schiff base proton acceptor and donor, a hallmark of rho

102 ied interaction network between chromophore, Schiff base, and counterion complex explaining the alter

103 rs with salicylaldehyde to the corresponding Schiff base allows analysis of the dr based on a change

104 tem, were synthesized from the corresponding Schiff bases of O-perbenzoylated (gluculopyranosylamine)

105 protease through the formation of a covalent Schiff base adduct of the pBzF residue with the epsilon-

106 avage of beta-hydroxy-ketones via a covalent Schiff base intermediate.

107 arbonyl of TPQ, forming a series of covalent Schiff base intermediates.

108 became trapped by MR1 as reversible covalent Schiff base complexes.

109 The results show that the BF-CS Schiff base Ag (I) complexes are embedded into MCNT netw

110 etization), and Hc (coercivity) of the BF-CS Schiff base composites reach 1.908 S cm(-1), 28.20 emu g

111 When the mass ratio of MCNTs and BF-CS Schiff base is 0.95:1, the conductivity, Ms (saturation

112 n nanotubes/BaFe12O19-chitosan (MCNTs/BF-CS) Schiff base Ag (I) complex composites were synthesized s

113 ate 3 that is in equilibrium with the cyclic Schiff base.

114 es of both the hemiaminal and the dehydrated Schiff base can be observed by CEST NMR, even when their

115 generally unstable, hydrated and dehydrated, Schiff base intermediates that often are unobservable by

116 as an internal aldimine with a deprotonated Schiff base.

117 tion of an isocyanide to a hydrazine derived Schiff base affords unique six-membered pyridotriazine s

118 anic frameworks (COFs), formed by the direct Schiff reaction between 1,3,5-tris(4-aminophenyl)benzene

119 e nanodisc environment leading to an earlier Schiff base deprotonation.

120 the mutation of which to Glu produced early Schiff base proton transfer and strongly inhibited chann

121 e visual pigments is necessary for efficient Schiff base hydrolysis.

122 ons were stained with hematoxylin and eosin, Schiff reagent, and fluorescein, to assess morphologic c

123 actions with His910 and Phe889, an essential Schiff base with Lys907 and a hydrogen bond with Tyr892.

124 )methane derivatives instead of the expected Schiff base products.

125 these homogeneous amyloid nanotubes exploit Schiff imine formation via the exposed lysines to effici

126 (PLP), apparently without a solvent-exposed Schiff base.

127 In view of such features, Schiff base condensations are thermodynamically controll

128 te lysine residue that is initially used for Schiff base formation in the internal aldimine and later

129 oxidised to alpha-aminoadipic acid and form Schiff bases structures.

130 , we show that 5fC bases in DNA readily form Schiff-base conjugates with Lys side chains of nuclear p

131 scent molecular rotors of boron derived from Schiff bases: (2,4,8,10-tetra-tert-butyl-6-phenyldibenzo

132 -Iodophenyl)imines A are readily formed from Schiff's base condensation of 2-iodoanilines with carbon

133 Furthermore, Schiff-base-modified peptides exhibit on average a 20% i

134 , (ii) dynamic covalent cross-linking (e.g., Schiff base formation, disulfide formation, reversible D

135 ct asymmetric aldol reaction between glycine Schiff bases and aldehydes is reported.

136 l side chains were also accessed via glycine Schiff base alkylation, further increasing the scope of

137 In a Perspective, Gordon Schiff discusses the importance of appropriately analyzi

138 ed pyrolysis of a series of heterobimetallic Schiff base complexes ensures a rigorous control of the

139 In 1864, Hugo Schiff, aged 30, discovered the reaction of aromatic ald

140 Discovered by Hugo Schiff, condensation between amine and aldehyde represen

141 lished by replacing the rapidly hydrolyzable Schiff-base moiety of first-generation members with a cy

142 itory action of a biologically inert Co(III) Schiff base (Co(III)-sb) complex.

143 e activation of a biologically inert Co(III) Schiff base [Co(III)-SB] complex to its protein inhibito

144 and characterization of a novel cobalt(III) Schiff base complex with methylamine axial ligands, and

145 Recently, we reported a Mn(III) Schiff base-type complex, Mn((tbu)dhbpy)Cl, where 6,6'-d

146 Heterobis imine Schiff base probe L is able to discriminate geometrical

147 ly conjugated oligomers of secondary imines (Schiff bases) present at relatively low concentrations.

148 and amino acid side chains in the immediate Schiff base vicinity are very well conserved.

149 midoxime acts as an internal general acid in Schiff-base formation.

150 Acid catalysis, which is often employed in Schiff base synthesis, radically changes the course of r

151 ation of the ion/ion intermediate results in Schiff base formation generated via reaction between a p

152 ccumulation of excess 11-cis-retinal and its Schiff-base conjugate and the formation of toxic bisreti

153 factors and does not form a protein-mediated Schiff base with the substrate, unlike most aldolases.

154 Here, using as model Schiff bases generated from salicylaldehydes and TRIS in

155 c scheme, the human rhodopsin exhibited more Schiff base deprotonation than bovine rhodopsin, which c

156 The N-alkylated indanylidenepyrroline (NAIP) Schiff base 3 is an unnatural alpha-amino acid precursor

157 for all steps of the mechanism, most notably Schiff base formation and hydrolysis.

158 lar surface coverage confirm the efficacy of Schiff base chemistry, at least with the terephthalaldeh

159 the protein sequence controls the extent of Schiff base deprotonation and accumulation of intermedia

160 wever, the rapid and reversible formation of Schiff base prohibits formation of alternative products,

161 The urea analysis relied on the formation of Schiff base under acidic conditions.

162 the amyloid fibril through the formation of Schiff bases, cross-linking the fibrils, which may preve

163 hat DOPAL interacts with aS via formation of Schiff-base and Michael-addition adducts with Lys residu

164 s reaction proceeds via in situ formation of Schiff-base followed by base mediated alkylation with ph

165 of 11-cis-retinal followed by hydrolysis of Schiff base (SB) and 2) hydrolysis of SB in dark state r

166 Specifically, interconversion of Schiff base and enamine intermediates, formed covalently

167 ohydride reduction confirmed the presence of Schiff base complexes.

168 not from inherent differences in the rate of Schiff base hydrolysis but rather from differences in th

169 etic strategy that regulates the sequence of Schiff base reaction via weak secondary interactions.

170 and, in the presence of O(2) , both types of Schiff base DOPAL-peptide intermediates rapidly react wi

171 m chemical models of three distinct types of Schiff base rotary motors.

172 aldehyde to form a hydrogel in situ based on Schiff base 2 as a low-molecular-weight gelator (LMWG).

173 nd synthetic strategies toward COFs based on Schiff-base chemistry, collects and rationalizes their p

174 nes), forming either hemiaminal (+148 Da) or Schiff base (imine, +130 Da) products.

175 the complex [(UO2 )(THF)(H2 L)] (L="Pacman" Schiff-base polypyrrolic macrocycle), is found and expla

176 arth trication in a binucleating polypyrrole Schiff-base macrocycle (Pacman) and bridged through a ur

177 inuclear magnesium complex of a polypyrrolic Schiff base macrocycle results in the formation of a new

178 I-Lumi II process that immediately precedes Schiff base deprotonation in the activation of rhodopsin

179 Mutation of the primary Schiff base counterion (VCOP(D108A)) produced a pigment

180 been exploited for over 150 years to produce Schiff bases, one of the most popular classes of compoun

181 s binding to 8-oxoG-containing DNA, promotes Schiff base formation, and stimulates its glycosylase an

182 re model compound 11-cis-retinyl-propylamine Schiff base demonstrate the direct isomerization of visu

183 rption spectrum consistent with a protonated Schiff base (lambda(max) = 420 nm).

184 y in this system is provided by a protonated Schiff base adduct of retinaldehyde and taurine (A1-taur

185 talytic cycle is facilitated by a protonated Schiff base form of the holoenzyme in which the linking

186 e capable of binding retinal as a protonated Schiff base is described.

187 0) energy surfaces (Phi(CI)) of a protonated Schiff base of all-trans retinal in protic and aprotic s

188 nal and form a covalent bond as a protonated Schiff base.

189 11-cis retinyl chromophore with a protonated Schiff-base (PSB11), UV pigments uniquely contain an unp

190 ilibrium between the phenolic and protonated Schiff base tautomeric forms of this intermediate.

191 is-retinal (11CR), by a covalent, protonated Schiff base linkage.

192 g the intermediate Opsin-derived, protonated Schiff base in the visual cycle with simple polarized al

193 to approximately 40 kcal/mol for protonated Schiff base (PSB) chromophore in rhodopsin.

194 nd H6, while deprotonation of its protonated Schiff's base triggers the rearrangement of the hydrogen

195 photoisomerization of the retinal protonated Schiff base (RPSB) chromophore.

196 ton, its chromophore, the retinal protonated Schiff base (RPSB), isomerizes from its native all-trans

197 neC backbone of all-trans retinal protonated Schiff base accelerates the electronic decay in solution

198 ollowing reduction of the retinal protonated Schiff base double bond.

199 photoisomerization of the retinal protonated Schiff-base in bacteriorhodopsin, isorhodopsin and rhodo

200 hysical properties of the retinal-protonated Schiff base chromophore in solution.

201 cally isomerizes the retinylidene protonated Schiff base both thermally and photochemically.

202 The pKa of the retinylidene protonated Schiff base was modulated from 2.4 to 8.1, giving rise t

203 connection of their retinylidene protonated Schiff bases to the outwardly located periplasmic side a

204 es E90, E123, D253, N258, and the protonated Schiff base (SBH), as well as nearby residues K93, T127,

205 cis-retinal and hydrolysis of the protonated Schiff base linkage between the 11-cis-retinal chromopho

206 ed bond-length alternation of the protonated Schiff base of 11-cis-retinal chromophore, induced by N8

207 e in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL).

208 t Arch variants, the pK(a) of the protonated Schiff-base linkage to retinal is near neutral pH, a use

209 transfer between the zwitterionic protonated Schiff base configuration and the neutral hydroxyimine t

210 ted at the edge of PLP opposite the reactive Schiff base.

211 the late M- (M2) with a deprotonated retinal Schiff base and the consecutive green-absorbing N-state

212 ge separation between the protonated retinal Schiff base (RSBH(+)) and its counterion complex.

213 In dark-adapted ChR2, the protonated retinal Schiff base chromophore (RSBH(+)) adopts an all-trans,C=

214 rhodopsins, which bind a protonated retinal Schiff base for light absorption, UV-absorbing rhodopsin

215 ncluding the D121-H87 cluster of the retinal Schiff base counterion and a glutamate at position 132 t

216 of the internal proton donor to the retinal Schiff base in the light-driven proton pump of Exiguobac

217 3) (Asp(253) in CrChR2) receives the retinal Schiff base proton during M-state formation.

218 rtate residue, the counterion to the retinal Schiff base, to a histidine.

219 as the internal proton donor to the retinal Schiff base.

220 bing rhodopsins bind an unprotonated retinal Schiff base.

221 plex has an outwardly connected retinylidene Schiff base like the repellent signaling forms of the SR

222 ex counterion to the protonated retinylidene Schiff base, and neutralization of the negatively charge

223 ecedes the deprotonation of the retinylidene Schiff base (i.e., formation of an M intermediate).

224 nts of proton transfer from the retinylidene Schiff base in several channelrhodopsin variants express

225 onfiguration that maintains the retinylidene Schiff base protonated when the channel is open.

226 king structures are determined by reversible Schiff-base formation, before irreversible Wittig olefin

227 nd cone visual pigments undergoes reversible Schiff base hydrolysis and dissociation following photob

228 See Schiff for a scientific commentary on this article.

229 adily available halogen sources and a simple Schiff base as the chiral catalyst.

230 ly immobilized to the host IL through simple Schiff base reaction.

231 donor, respectively, of the photoactive site Schiff base (SB) proton.

232 s selectivity by forming an unusually stable Schiff base with lysine 907 in the IRE1 endonuclease dom

233 ntered radical character of an excited state Schiff base is unique, requiring only violet light in th

234 ium(II) and tin(II) by using the substituted Schiff base 2,6-diacetylpyridinebis(2,6-diisopropylanil)

235 es (MWCNT), chitosan and a novel synthesized Schiff base (SB) (TiO2/MWCNT/CHIT/SB) on the surface of

236 Metal template Schiff base condensations have produced multinuclear met

237 certain cases, however, compounds other than Schiff bases have been reported to result from such reac

238 aracteristics and they were more stable than Schiff base adducts at 60 degrees C.

239 edominance of intermediate MRPs, such as the Schiff base compounds.

240 between positions C10 and C15 as well as the Schiff base nitrogen in the ground state in comparison t

241 by formation of a direct H-bond between the Schiff base and Asn87.

242 observe a deuterium equidistant between the Schiff base and the C-terminal carboxylate of the substr

243 rtate 253 accepts the proton released by the Schiff base (t(1/2) = 10 mus), with the latter being rep

244 Syntheses of these COFs were done by the Schiff base reactions of 1,3,5-triformylphloroglucinol (

245 For pi-conjugated COFs, the Schiff base condensation of aldehydes and amines is the

246 ing sugars react with asparagine to form the Schiff base before decarboxylation, to generate acrylami

247 ges in the K-state propagating away from the Schiff base along the polyene chain.

248 and its ability to accept a proton from the Schiff base during the photocycle.

249 ing the primary phototransition and from the Schiff base to Glu-169 during P2 (380) formation.

250 oplasmic half-channel, located 15 A from the Schiff base.

251 bly being a primary proton acceptor from the Schiff base.

252 f the carbinolamine intermediate to give the Schiff base and to function as a general acid/base.

253 ctions of TCNQF (-) radicals (H2valpn is the Schiff base from the condensation of o-vanillin with 1,3

254 lidene-pyrroline chromophore that mimics the Schiff base of rhodopsin and can be used to introduce li

255 d from hydroxyl-bearing amino acids near the Schiff base in different visual pigments: at site 292 (A

256 or other residues slows reprotonation of the Schiff base (decay of the M intermediate) by more than 2

257 he retinyl chromophore and hydrolysis of the Schiff base (SB) through which the retinyl chromophore i

258 omerization and dark state hydrolysis of the Schiff base by 1-2 orders of magnitude.

259 embrane voltage modulates protonation of the Schiff base in a 13-cis photocycle intermediate (M right

260 refore suggest that the reprotonation of the Schiff base in ESR is preceded by transient protonation

261 energetics and the protonation state of the Schiff base in retinal, the covalently bound ligand resp

262 eins was confirmed by NaBH4 reduction of the Schiff base intermediate and kinetics studies.

263 ce experiments confirm the assignment of the Schiff base nitrogen, and additional (13)C, (15)N, and (

264 fluctuations in the protonation state of the Schiff base occur prior to forming the activated MII sta

265 that deprotonation and reprotonation of the Schiff base take place on the same (outer) side of the m

266 achieved by preventing reprotonation of the Schiff base through a mutation of the primary proton don

267 n and the deprotonation/reprotonation of the Schiff base, are coupled to the channel-opening mechanis

268 channel occurs prior to deprotonation of the Schiff base.

269 changes dramatically with protonation of the Schiff base.

270 nary support increased with each step of the Schiff-base process: poly(Ethylene glycol Dimethacrylate

271 hodopsin acts as the primary acceptor of the Schiff-base proton in low-efficiency channelrhodopsins.

272 h the internal aldimine is protonated on the Schiff base N.

273 inylidene-phosphatidylethanolamine (PE), the Schiff-base conjugate of 11-cis-retinal and PE, from the

274 Recently, the Schiff-base chemistry or dynamic imine-chemistry has bee

275 t M-states have been observed reflecting the Schiff base reorientation after the deprotonation step.

276 ay observed in the mutants suggests that the Schiff base proton is one of the displaced charges.

277 for immobilization of DNA probes through the Schiff base reaction.

278 st, reductive conditions were applied to the Schiff base to yield secondary amine 3, which is also a

279 p-Azo and Tp-Stb) were synthesized using the Schiff base reaction between triformylphloroglucinol (Tp

280 new channelrhodopsin mechanism, in which the Schiff base not only controls gating, but also serves as

281 the pyrimidine ring is maintained, while the Schiff base intermediate is preferred if the C5 horizont

282 chiff base intermediates, explaining why the Schiff base NMR signals are rarely observed.

283 ter-mediated H-bonding interactions with the Schiff base linkage.

284 crements of 54 and 134 amu, corresponding to Schiff base and dihydropyridine (DHP)-type adducts, resp

285 The transient Schiff base conjugate that the primary amine of taurine

286 est results were obtained using a tridentate Schiff base aluminum(III) Lewis acidic complex, 1H-1,2,3

287 Treatment of alpha-silylaryl triflates, Schiff bases, and alkynes generated polysubstituted pyrr

288 When combined with amino acids they undergo Schiff base formation, decarboxylation and alpha-aminoke

289 UV pigments uniquely contain an unprotonated Schiff-base (USB11).

290 ostatic effects surrounding the unprotonated Schiff base (USB) retinyl chromophore in the UV pigment.

291 hemoglobin amino groups to produce unstable Schiff base complexes that can dissociate or rearrange t

292 One of the most widely used Schiff base ligands, the "salen" ligand, has been extens

293 ied with monoclonal anti-cTnI antibodies via Schiff reaction based chemistry.

294 mpounds that transiently sequester atRAL via Schiff base formation ameliorate retinal degeneration.

295 nks) revealed that the reaction proceeds via Schiff base chemistry facilitated by lysine residues.

296 The reductive half-reaction proceeds via Schiff base chemistry, in which the primary amine substr

297 rimary alkoxides and diaminopyrimidines with Schiff base formation and subsequent annulation in the p

298 ox-mediated coupling of benzylic ethers with Schiff bases has been accomplished.

299 ty of the immobilised polymer generated with Schiff-base activation and immobilisation scheme.

300 and is described by a multisquare model with Schiff base deprotonation at the lumirhodopsin I interme