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1 (prostate), MDA-MB-231 (breast), and Jurkat (T-cell leukemia).
2 ackfan anemia (DBA), congenital asplenia and T cell leukemia.
3 a spectrum of human malignancies, including T cell leukemia.
4 d retroviruses with the former causing adult T cell leukemia.
5 fficacy in mouse models of human sarcoma and T cell leukemia.
6 pathy/tropical spastic paraparesis and adult T cell leukemia.
7 ons in both the induction and maintenance of T cell leukemia.
8 perturbation of its activity often leads to T cell leukemia.
9 and MAPK kinase activities in CD3-activated T cell leukemia.
10 ll lines and dampens global transcription in T cell leukemia.
11 ed ribosomal mutation in acute lymphoblastic T-cell leukemia.
12 of thymocytes, and subsequent generation of T-cell leukemia.
13 ors was associated with improved outcomes in T-cell leukemia.
14 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia.
15 humans and is etiologically linked to adult T-cell leukemia.
16 cell transformation and development of adult T-cell leukemia.
17 event in the process of ZNF198-FGFR1-induced T-cell leukemia.
18 irus type-1 is the causative agent for adult T-cell leukemia.
19 nt of the aggressive and fatal disease adult T-cell leukemia.
20 1 (HTLV-1) is the etiological agent of adult T-cell leukemia.
21 infects CD4+ T lymphocytes and causes adult T-cell leukemia.
22 investigate the role of this interaction in T-cell leukemia.
23 Nbn (-/mid8) mice developed highly penetrant T cell leukemias.
24 m cells downstream of MYC in human and mouse T-cell leukemias.
25 y reduced in CD19(+) spleen B cells from Emu-T cell leukemia 1 (TCL1) transgenic mice relative to the
26 tudies revealed that ROR1 could complex with T-cell leukemia 1 (TCL1) in CLL, we crossed these animal
31 photropic virus type 1 (HTLV-1) causes adult T-cell leukemia, a disease commonly associated with hype
32 minimal overlap with known Notch targets in T cell leukemia and developing T cells, highlighting the
34 ogenesis related to the progression of adult T cell leukemia and HTLV-1-associated myelopathy/tropica
36 ic virus type 1 (HTLV-1) mainly causes adult T cell leukemia and predominantly immortalizes/transform
37 genetic aberrations that promote acute B and T cell leukemias and the mechanisms of cell transformati
40 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropica
41 virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is associated with a variety of lymp
42 mature lymphocytes, develop multiple B- and T-cell leukemia and lymphoma subtypes, supporting an onc
43 -1), an etiological factor that causes adult T-cell leukemia and lymphoma, has a crucial role in init
47 virus type 1 (HTLV-1) infection causes adult T-cell leukemia and several lymphocyte-mediated inflamma
48 kemia virus type 1 (HTLV-1)-associated adult T-cell leukemia and T-cell lymphoma (ATL) are aggressive
49 Tipifarnib reduced cell viability in these T-cell leukemia and TCL cell lines, induced apoptosis an
51 with several serious diseases, such as adult T-cell leukemia and tropical spastic paraparesis/myelopa
52 ry tumor virus (MMTV) variant, often induces T-cell leukemias and lymphomas by c-myc activation follo
55 and constitutive Notch signaling potentiates T cell leukemia as well as Drosophila neuroblast tumors.
61 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/t
62 1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/t
64 s-1 (HTLV-I) is the etiologic agent of adult T-cell leukemia (ATL) and the neurological disorder HTLV
65 oup that first identified a cluster of adult T-cell leukemia (ATL) cases in Japan, provided conclusiv
73 s are implicated in the development of adult T-cell leukemia (ATL), a T-cell malignancy caused by HTL
74 e-I (HTLV-I) is the etiologic agent of adult T-cell leukemia (ATL), an aggressive lymphoproliferative
75 rus type 1 (HTLV-I) is associated with adult T-cell leukemia (ATL), an aggressive lymphoproliferative
76 irus type 1 (HTLV-1) that recapitulate adult T-cell leukemia (ATL)-like leukemic symptoms and display
85 distinct signaling proteins in a panel of 13 T-cell leukemia cell lines treated with a gamma-secretas
88 GBP with selective cytotoxicity toward human T-cell leukemia cells and indicate its potential use in
89 zomib (an agent whose cytotoxicity in Jurkat T-cell leukemia cells is dependent on Noxa) was examined
90 ked to a spectrum of diverse diseases: adult T cell leukemia, encephalomyelopathy, and predisposition
91 tudies, performed in translational models of T cell leukemia, establish a mechanism-based rationale f
92 HTLV) type 1, the etiological agent of adult T-cell leukemia, expresses the viral oncoprotein Tax1.
95 oncogene (encoding the transcription factor T cell leukemia homeobox protein-1) has a major role in
96 n proposed to have tumor suppressor roles in T-cell leukemia homeobox 1/3-transformed human T-ALL cel
97 NA binding site for the poorly characterized T-cell leukemia homeobox 3 (TLX3) TF was confirmed with
101 ell leukemia virus 1 (HTLV-1)-mediated adult T cell leukemia is associated with the ability of viral
102 ood, Nagai et al provide evidence that adult T-cell leukemia is hierarchically organized and sustaine
103 leukemia virus type 1 (HTLV-1)-induced adult T-cell leukemia is linked to the expression of the viral
104 lective and potent cytotoxicity toward human T-cell leukemia Jurkat cells compared with a panel of ca
107 , pTa, Gata3, and Runx1, in both Ikaros null T cell leukemia lines and Ikaros null primary thymocytes
108 -cell leukemia virus (HTLV)-associated adult T-cell leukemia lymphoma (ATLL) can be identified years
113 on has only brought limited success in adult T cell leukemia/lymphoma (ATL) and in multiple sclerosis
114 kemia virus type 1 (HTLV-1)-associated adult T cell leukemia/lymphoma (ATL) cells as a model system.
117 1 (HTLV-1) is the ethological agent of adult T cell leukemia/lymphoma (ATLL) and a number of lymphocy
121 ype 1 (HTLV-1) is a causative agent of adult T cell leukemia/lymphoma and a variety of inflammatory d
124 virus type 1 (HTLV-1) infection causes adult T-cell leukemia/lymphoma (ATL) and is associated with a
125 d with the lymphoproliferative disease adult T-cell leukemia/lymphoma (ATL) and the neurodegenerative
130 -cell leukemia virus type 1-associated adult T-cell leukemia/lymphoma (ATL) typically has survivals m
131 sactivator initiates transformation in adult T-cell leukemia/lymphoma (ATL), a highly aggressive chem
132 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma (ATL), a malignancy of CD4(+) T
135 ), anaplastic large-cell lymphoma, and adult T-cell leukemia/lymphoma (ATLL) and a lower incidence of
136 r A (RHOA) hotspot mutations among the adult T-cell leukemia/lymphoma (ATLL) category have opposite b
139 ic virus type-1 (HTLV-1) that initiate adult T-cell leukemia/lymphoma (ATLL) remain unclear, in part
140 We recently reported the first case of adult T-cell leukemia/lymphoma (ATLL) that responded rapidly t
141 CD8(+) T cells, yet this virus causes adult T-cell leukemia/lymphoma (ATLL) that typically has a CD4
145 ouse studies indicate that activation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contribu
146 mmon human leukemia and dysregulation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contribu
150 ive anaplastic large cell lymphoma, 14 adult T-cell leukemia/lymphoma and 44 extranodal NK/T-cell lym
151 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma and HTLV-1-associated myelopath
152 causes two distinct pathologies termed adult T-cell leukemia/lymphoma and tropical spastic paraparesi
153 virus type 1 (HTLV-1) is the cause of adult T-cell leukemia/lymphoma as well as tropical spastic par
154 To study the impact of oncogenic K-Ras on T-cell leukemia/lymphoma development and progression, we
157 cogenic driver mutation, promotes aggressive T-cell leukemia/lymphoma in patient carriers, although t
163 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma, and it encodes a number of non
164 l lymphoma, cutaneous T-cell lymphoma, adult T-cell leukemia/lymphoma, and other peripheral T-cell ly
165 ided highly diverse results on the issues of T-cell leukemia/lymphoma-initiating cells (T-LICs) and p
171 ctivation in hematopoietic precursors caused T-cell leukemia/lymphomas (T-ALL) and pure red blood cel
172 t in a transgenic mouse model of MYC-induced T-cell leukemia, MYC, maintains self-renewal in Sca1(+)
174 ferent human cancers including lymphoblastic T-cell leukemia, pancreatic cancer, melanoma and rhabdom
177 Adult patients with acute lymphoblastic T cell leukemia (T-ALL) have a very poor prognosis and f
178 te and cause myeloproliferative disorder and T cell leukemia (T-ALL) when induced in the bone marrow
179 nsmembrane protein highly expressed in acute T-cell leukemia (T-ALL) and in a subset of peripheral T-
180 ly in primary and secondary tissues, we used T-cell leukemia (TCL)1 cells reactive with the autoantig
192 ced apoptosis, we used TRAIL-resistant human T cell leukemia virus type 1 (HTLV-1)-associated adult T
193 cytes) to the total viral burden in 22 human T cell leukemia virus type 1 (HTLV-1)-infected individua
196 ssociations in three viral infections: Human T cell Leukemia Virus type 1, Human Immunodeficiency Vir
197 Furthermore, the Tax oncoprotein of human T cell leukemia virus type I targeted this complex for i
198 l virus, human immunodeficiency virus, human T cell leukemia virus, human papilloma virus, hepatitis
200 recognizes the foreign Ag Tax from the human T cell leukemia virus-1 when presented by the class I MH
201 sible link with the autoimmune disease human T cell leukemia virus-1-associated myelopathy/tropical s
205 ly discovered the antisense protein of human T-cell leukemia virus (HTLV) type 2 (APH-2), whose messe
206 demonstrate that driver mutations for human T-cell leukemia virus (HTLV)-associated adult T-cell leu
207 ntification of the genes necessary for human T-cell leukemia virus (HTLV-1) persistence in humans may
209 cation and partial characterization of human T-cell leukemia virus (HTLV; now known as HTLV-1) produc
215 ence techniques in real time with both human T-cell leukemia virus type 1 (HTLV-1) and human immunode
219 et al report that vaccination against human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipp
221 butes to HTLV-1 infectivity.IMPORTANCE Human T-cell leukemia virus type 1 (HTLV-1) causes a variety o
223 ally integrated form of the retrovirus human T-cell leukemia virus type 1 (HTLV-1) contains identical
224 rs proposed a model for this region of human T-cell leukemia virus type 1 (HTLV-1) Env in which expul
234 Surprisingly, the NC protein from human T-cell leukemia virus type 1 (HTLV-1) is an extremely po
247 d, Fujikawa et al demonstrate that the human T-cell leukemia virus type 1 (HTLV-1) oncoprotein Tax in
248 In the present study, we show that the Human T-cell Leukemia Virus Type 1 (HTLV-1) oncoprotein Tax is
249 uggested to be largely dispensable for human T-cell leukemia virus type 1 (HTLV-1) particle biogenesi
254 -risk human papillomavirus (HPV) E6 or human T-cell leukemia virus type 1 (HTLV-1) Tax oncoproteins.
255 lishment of humanized mice infected by human T-cell leukemia virus type 1 (HTLV-1) that recapitulate
258 The retroviral oncoprotein Tax from human T-cell leukemia virus type 1 (HTLV-1), an etiological fa
259 udy, we found that HBZ, encoded by the Human T-cell Leukemia Virus type 1 (HTLV-1), binds to multiple
260 , which can result from infection with human T-cell leukemia virus type 1 (HTLV-1), is associated wit
261 infection by HIV-1, HIV-1Deltavif, and human T-cell leukemia virus type 1 (HTLV-1), while significant
269 s level of BIC by up to 70% in EBV- or human T-cell leukemia virus type 1 (HTLV1)-transformed cell li
271 The Tax oncoprotein encoded by the human T-cell leukemia virus type 1 plays a pivotal role in vir
272 Unlike the resistance of HIV-1 and human T-cell leukemia virus type 1 to hA3G, the resistance of
273 ion of additional human tumor viruses--human T-cell leukemia virus type 1, hepatitis C virus, and Kap
277 viruses in the transplant population: human T-cell leukemia virus type 1; hepatitis E virus; bocavir
295 sease onset in murine models of Notch-driven T-cell leukemia, whether Dicer1-processed miRNAs are ess
296 ted mAb by immunizing mice with Jurkat acute T cell leukemia, which binds ILT3.Fc to its membrane.
297 vating IKK, yet only HTLV-1 infection causes T cell leukemia, which correlates with persistent activa