ライフサイエンスコーパス: T-cell number

1 ll lineages, with a concomitant reduction in T cell number.

2 g animals, despite significant reductions in T cell number.

3 tive cell death prevents further increase in T cell number.

4 and it was accompanied by reduced regulatory T cell number.

5 ice showed a 2- to 3-fold increase in memory T cell number.

6 ports, did not lead to an increase in memory T cell numbers.

7 it did not alter conventional CD4(+)Foxp3(-) T cell numbers.

8 s were negatively correlated with regulatory T cell numbers.

9 ses tumor associated inflammation and CD8(+) T cell numbers.

10 rely diminished mucosal-associated invariant T cell numbers.

11 node) displayed no such increases in CD8(+) T cell numbers.

12 ymic output, potentially reducing peripheral T cell numbers.

13 tween naive, memory, and Foxp3(+) regulatory T cell numbers.

14 tantly decreased inflammatory and regulatory T cell numbers.

15 ed in Tbx21(-/-) mice by reducing regulatory T cell numbers.

16 fication of cytokine profiles and regulatory T cell numbers.

17 ere cytokine secretion levels and regulatory T cell numbers.

18 otype and a selective decrease in regulatory T cell numbers.

19 (DN1) stage, leading to decreased peripheral T cell numbers.

20 ollowed by an equally extensive reduction in T cell numbers.

21 tion was accompanied by a decrease in NK and T cell numbers.

22 ions between LLP2A signal and macrophage and T cell numbers.

23 substantial than the reduction of total CD4 T cell numbers.

24 This resulted in a 1400-fold increase in T cell numbers.

25 immune responsiveness or T reg and effector T cell numbers.

26 iated contraction and do not increase memory T cell numbers.

27 e can enhance NK cell and tumor-specific CD8 T cell numbers.

28 in mice results in diminished peripheral CD8 T cell numbers.

29 oire formation, receptor editing, and B- and T-cell numbers.

30 al enumeration of total and antigen-specific T-cell numbers.

31 r peripheral deletion to maintain peripheral T-cell numbers.

32 rease in circulating CD4(+) T-cell and naive T-cell numbers.

33 tions were observed between asthma and B- or T-cell numbers.

34 gen-presenting capacity of DCs and increased T-cell numbers.

35 with a marked decrease in splenic gammadelta T-cell numbers.

36 the HIV-1-controllers with diminished CD4(+)T-cell numbers.

37 e with BCG in inducing Ag85B-specific CD4(+) T-cell numbers.

38 elimination of the latter decreasing CD4(+) T-cell numbers.

39 D, with no significant differences in CLA(-) T-cell numbers.

40 natural killer, T helper 17, and regulatory T-cell numbers.

41 infections, despite normal peripheral CD4(+) T-cell numbers.

42 lated with ~500% increase in effector CD8(+) T-cell numbers.

43 eased circulating CD25(+) T cells and CD4(+) T-cell numbers.

44 ry encompassed the recovery of normal CD4(+) T cell numbers, a low ratio of effector to central memor

45 31 induces profound reduction of peripheral T cell numbers after oral dosage and confers pronounced

46 4+ T-cell numbers were lower than naive CD8+ T-cell numbers; after HAART, a greater increase in naive

47 in a marked relative increase in regulatory T-cell numbers among the CD4 T-cell subset of the challe

48 ally in T cells led to a strong reduction in T cell number and a shift toward the effector/memory phe

49 correlated with antitumor efficacy, whereas T cell number and cytokine profile were not.

50 ne the effect of gammaherpesvirus latency on T cell number and differentiation during subsequent hete

51 e can be modulated by preexisting memory CD8 T cell number and the intensity of inflammation during r

52 Thus, OX40 signals regulate T cell number and viability through the NF-kappaB1 pathw

53 70% reduction in activated CD4(+) and CD8(+) T cell numbers and 20-50% reductions in IFN-gamma-produc

54 lood counts (CBC), antibody binding of RBCs, T cell numbers and activation, hematopoietic progenitor

55 Absence of CD18 led to diminished CD4+CD25+ T cell numbers and affected both thymic and peripheral d

56 After one or two inoculations of MVA, the T cell numbers and antibody titers equaled or exceeded t

57 led clodronate liposomes reduced both NK and T cell numbers and attenuated weight loss.

58 y to LNG-treated mice at 1 dpi restored lung T cell numbers and chlamydial burden at 12 dpi to levels

59 T cells resulted in decreased peak donor CD8 T cell numbers and decreased CTL effector function due t

60 matically increased Vbeta14(+) thymocyte and T cell numbers and decreased numbers of cells expressing

61 revealed a positive association between CD8 T cell numbers and decreased proinflammatory function of

62 iency in T cells led to decreased peripheral T cell numbers and defective homeostatic proliferation,

63 slow and causes a gradual increase in total T cell numbers and differentiation into cells with featu

64 -/-) mice display a slight reduction in CD8+ T cell numbers and do not effectively clear a pulmonary

65 er, viral peptide-specific CD4(+) and CD8(+) T cell numbers and effector cell development were signif

66 nt viral infection erodes virus-specific CD8 T cell numbers and effector function, with a concomitant

67 ession on hematopoietic cells inhibited CD8+ T cell numbers and function after LCMV CL-13 infection.

68 Deficiencies in CD8 T cell numbers and function also explained the observati

69 rol the risk of leukemia, we assessed NK and T cell numbers and function in IL-2Rgamma(c)(-/-) mice r

70 Maintenance of CD8(+) T cell numbers and function was dependent on Th cells th

71 rance, but increased IL-22 in vivo decreased T cell numbers and functions in the liver and lymphoid t

72 o partially restore NY-ESO-1-specific CD8(+) T cell numbers and functions, increasing the likelihood

73 oliferation functions to maintain peripheral T cell numbers and is regulated by cytokines.

74 only 3% of wild-type CD45 activity restored T cell numbers and normal cytotoxic T cell responses.

75 amma (IFN-gamma) expression, increases naive T cell numbers and reduces effector T cell numbers in ad

76 ion with IL-15 boosted antigen-specific CD8+ T cell numbers and resulted in a cooperative effect on t

77 spleens were studied at intervals for B and T cell numbers and subsets and frequency of anti-double-

78 BTLA expression limited gammadelta T cell numbers and sustained normal gammadelta T cell su

79 In this study, we show that reduced T cell numbers and the resulting exaggerated homeostatic

80 Patients with AT have reduced B- and T-cell numbers and a highly variable immunodeficiency.

81 14-day Ang II infusion increased gammadelta T-cell numbers and activation in the spleen of wild-type

82 with poor prognosis, in addition to reduced T-cell numbers and activity with disease transformation.

83 CVC increased liver T-cell numbers and attenuated Il-2 expression without an

84 assays showed accelerated restoration of CD4 T-cell numbers and function.

85 uclear cells was assayed, as were regulatory T-cell numbers and function.

86 ry T-cell regeneration that preserves CD4(+) T-cell numbers and functions above the threshold associa

87 Cs during T-cell priming, whereas allogeneic T-cell numbers and homing in lymphoid and GVHD target or

88 ific HLA multimers to enumerate CMV-specific T-cell numbers and select cells to assess chimerism stat

89 found that Neu5Gc exposure reduced IL-17(+) T-cell numbers and supported differentiation of regulato

90 regression after SCT, absolute WT1(+) CD8(+) T-cell numbers and WT1 expression were studied for each

91 r vaccination, absolute PR1 and WT1(+)CD8(+) T-cell numbers and WT1 expression were studied weekly af

92 in TIL cultures was associated with reduced T cell numbers, and further functional studies demonstra

93 Protein acetylation, regulatory T-cell numbers, and circulating angiogenic factors did n

94 nd bacterial burden, restored splenic CD4(+) T-cell numbers, and increased the frequency of Ehrlichia

95 CD4(+) T-cell frequencies, decreased CD8(+) T-cell numbers, and resolution of CD8(+) T-cell alveolit

96 nd angiogenic capacities of EPCs, angiogenic T-cell numbers, and vascular endothelial growth factor e

97 Significant B and T cell numbers are generated in RAG1(c/c) mice, showing

98 T cell numbers are maintained within narrow ranges in vi

99 how in this article that circulating Vdelta1 T cell numbers are particularly high in patients with HI

100 Competition for these ligands declines when T cell numbers are reduced and causes residual naive T c

101 Furthermore, we find that gammadelta T cells numbers are increased in Itk(-/-) mice, most not

102 ses in inflammation, coagulation, and CD8(+) T-cell numbers are associated with an elevated cardiovas

103 ric PTLD patients, pretreatment EBV-specific T-cell numbers are in the range of healthy controls.

104 Although overall T-cell numbers are normal, both follicular helper and me

105 Stat1(-/-) mice however have normal CD4(+) T cell numbers as innate STAT1 signaling is required for

106 ncreased cell recruitment with higher CD4(+) T cells numbers as well as increased IFN-gamma and TNF-a

107 ete lack of B cells and dramatically reduced T cell numbers, as shown by Rag1(-/-) blastocyst complem

108 hase or protect against the waning of memory T cell numbers at later times after infection.

109 ation and apparent proliferation, with large T cell numbers at the Ag-positive tumor as early as day

110 Further, virus-specific T cell numbers at this site of infection are maintained

111 patients had profound defects in CD4 and CD8 T-cell numbers at diagnosis that did not recover during

112 served a transient increase in CD4+ and CD8+ T-cell numbers at the residual tumor after androgen abla

113 adually exceeded bystander p18-specific CD8+ T-cell numbers, both populations peaked concurrently wit

114 proliferation is suppressed by increases in T cell numbers but not by adoptive transfer of regulator

115 significantly increased Ag-specific effector T cell numbers, but does not result in increased numbers

116 nced IL-2 signals increase peak effector CD8 T cell numbers, but only early IL-2 signals enhance memo

117 e manipulated to improve HIV-specific CD8(+) T cell numbers, but possibly not all functions in vivo.

118 pathogen reencounter increases memory CD8(+) T cell numbers, but the impact on memory CD8(+) T cell d

119 gh negative regulation of natural regulatory T cell numbers by inhibiting the development of MHCII(lo

120 ific regulatory T cells, boosting regulatory T cell numbers by injecting IL-2 immune complexes dampen

121 hosis at 7 days and a 30% decrease in CD4(+) T-cell numbers by 10 days.

122 rs, and strategies to amplify tumor-reactive T-cell numbers by immunization or ex vivo expansion foll

123 Many studies have shown that amplifying T-cell numbers by prime-boost vaccination is most effect

124 ation only had a modest impact on recovering T cell numbers, CD8+ T cells from vaccinated patients co

125 CTLA-4 blockade resulted in lower memory CD8 T cell numbers compared with the DC+early IL-2 treatment

126 In RA patients, autoreactive T cell numbers correlated with disease activity and were

127 CD4+ T-cell numbers correlated positively with fasting insuli

128 Upon challenge with Y. pestis, pulmonary T-cell numbers decline in naive mice, whereas immunized

129 however, T cell exit slowed significantly as T cell numbers declined.

130 urthermore, after SHIV-89.6P infection, CD4+ T-cell numbers declined less and survival was longer in

131 By contrast, bystander CD8+ T-cell numbers declined to background numbers following

132 Memory CD8(+) T cell numbers decreased gradually in the absence of CD4

133 Antigen-specific T cell numbers decreased only 2-fold after 6 months.

134 The age-related recovery of the T-cell number depended on a homeostatic peripheral proli

135 Failure to normalize CD4(+) T-cell numbers despite effective antiretroviral therapy

136 ress to simian AIDS and that maintain stable T-cell numbers despite high levels of viral replication

137 Minimal cDC and CD8 T-cell number differences after low-dose MCMV in D(k) di

138 spontaneous EAE, the number of MBP-specific T cell numbers does not build up gradually in the CNS; i

139 Lckcre(tg) Grb2-deficient mice show reduced T cell numbers due to impaired negative and positive sel

140 counts and may contribute to the decrease in T cell numbers during late HIV-1 infection.

141 CD4(+) T cell numbers even declined after stimulation by pp65(4

142 T cell numbers expand 20-fold and a majority secretes IL

143 onse to antigen stimulation to confer CD8(+) T cell-number expansion and effector functions against d

144 cell survival and fitness during peripheral T cell-number expansion in response to virus infection.

145 between virus and host that occurs when CD4+ T cell numbers fall below a level that can sustain immun

146 on, E2F1/E2F2 DKO mice do not recover normal T cell numbers following exposure to a sublethal dose of

147 f therapeutic avenues aimed at modulating DN T cell number for the prevention of autoimmune diseases.

148 ent reduction in mean circulating CD25+ CD4+ T cell number, from 83 +/- 16 cells/microl to a nadir of

149 We reported previously that normal T-cell numbers, function, and repertoire developed by 3

150 Although pN-specific T-cell numbers gradually exceeded bystander p18-specific

151 f the transferred T cells, even after stable T cell numbers have been reached, suggests that active c

152 in either CD30 or OX40 alone reduced CD4(+) T cell numbers, however, in mice deficient in both OX40

153 upon reactivation and preexisting memory CD8 T cell number (i.e., primary memory CD8 T cell precursor

154 ulation blockade also reduced virus-specific T-cell numbers, illustrating that sustained interactions

155 icant increases in dendritic cell and CD8(+) T cell number in advanced tumor-bearing mice compared wi

156 es naive T cell numbers and reduces effector T cell numbers in adipose tissue.

157 CD4 T cell numbers in B6.muMT(-/-) spleens were 10% of that

158 in psoriasis pathogenesis, but inflammatory T cell numbers in blood, as well as the relative importa

159 resonance imaging (MRI), and higher peak CAR-T cell numbers in blood, but not cerebrospinal fluid (CS

160 gnificantly increased median B cell, but not T cell numbers in both cohorts, with a trend for increas

161 d by gut but not skin dysbiosis, and reduced T cell numbers in both sites.

162 led to a marked reduction of eosinophil and T cell numbers in bronchoalveolar lavage fluid compared

163 Ibrutinib markedly increased CD4+ and CD8+ T cell numbers in CLL patients.

164 lpha18 leads to a complete restoration of NK T cell numbers in fyn(-/-) mice.

165 In this study, we found that T cell numbers in Grb2(fl/fl) CD4cre(tg) mice were norma

166 to reduced virus titers and increased CD8(+) T cell numbers in high- but not low-pathological infecti

167 K cells and contraction of CD4(+) and CD8(+) T cell numbers in individual patients in vivo provides s

168 es were profoundly reduced in blood, whereas T cell numbers in lymph nodes and spleen were at or near

169 pression in LMP7(-/-) mice or reduced CD8(+) T cell numbers in MECL-1(-/-) mice.

170 (+) mice and a continued reduction in CD4(+) T cell numbers in mesenteric lymph nodes.

171 biota also failed to fully expand intestinal T cell numbers in mice.

172 y lymphoid organs, whereas it expanded naive T cell numbers in nonlymphoid tissues; these effects wer

173 well in differences in protective memory CD8 T cell numbers in outbred individuals.

174 l therapy (cART) substantially restores CD4+ T cell numbers in peripheral blood, but the gut compartm

175 During infection, naive T cell numbers in peripheral lymphoid organs increase.

176 CD4(+) T cell numbers in the airways of CRA-challenged abr(-/-)

177 proved lung compliance, and increased CD8(+) T cell numbers in the airways.

178 We observed increases in OVA-specific CD8(+) T cell numbers in the local lung compartments (bronchoal

179 Memory CD8 T cell numbers in the lungs and noninvolved organs 100 d

180 Despite normal T cell numbers in the skin, Cxcr3(-/-) mice exhibited dr

181 erentiated T cells in the thymus and altered T cell numbers in the spleens of A20 mutant mice.

182 pproaches to the therapeutic manipulation of T cell numbers in vivo.

183 In these mice, T-cell number in lymph nodes was reduced by 27%.

184 ed bone resorption by >85% and decreased the T-cell number in periodontal tissues.

185 STC1 had minimal effects, however, on both T-cell number in the glomeruli and interstitium and on c

186 This leads to T-cell numbers in adulthood that are minimally decreased

187 tment results in enhanced local and regional T-cell numbers in both the skin and SLN.

188 t(W-sh/W-sh) hosts correlated with increased T-cell numbers in lymph nodes, liver, and gastrointestin

189 lted in enhanced thymopoiesis and peripheral T-cell numbers in middle-aged recipients of an allogenei

190 reduction in dendritic epidermal gammadelta T-cell numbers in the epidermis, indicating that these p

191 esults in dramatically decreased CD4 and CD8 T-cell numbers in the lamina propria of both small and l

192 were followed by relatively high and stable T-cell numbers in the SIV-infected macaques with a slow-

193 lecule, they have the potential to influence T-cell numbers in the skin through chemokine production

194 been linked to a failure to normalize CD4(+) T-cell numbers in treated human immunodeficiency virus (

195 ERRalpha deficiency reduced activated T-cell numbers in vivo and cytokine production in vitro

196 uced spleen and lymph node CD4(+) and CD8(+) T cell numbers, including naive, activated, and Foxp3(+)

197 ction with vaccinia virus, dermal gammadelta T cell numbers increased 10-fold in the infected ear and

198 ed FOXP3(lo/-)CD4 T cells while FOXP3(hi)CD4 T cell numbers increased.

199 Mucosal CD3, CD4, and CD8 T-cell numbers increased following infection.

200 Furthermore, CD8+ T-cell numbers increased more than twofold, mainly due t

201 ited T cell reconstitution, decreased memory T cell numbers, increased the relative frequency of Treg

202 0-enhancement of tumor immunity and effector T cell numbers is decreased in middle-aged mice and was

203 ermine whether the quantitative reduction in T-cell numbers is due to an intrinsic T-cell defect or w

204 Although the age-related fall in CD8(+) T-cell numbers is well established, neither the underlyi

205 Although TNF neutralization reduced T cell numbers, its coneutralization with IL-10 unexpect

206 rapy dramatically increased antigen-specific T-cell numbers leading to enhancement in the survival of

207 n-induced cell death, IL-21 sustained CD8(+) T cell numbers long term as a result of increased surviv

208 individuals is often characterized by lower T cell numbers, lower naive/memory T cell ratios, and lo

209 All patients with low CD3(+) T-cell numbers (<500 cells/muL) also had markedly decrea

210 tion and that a physiological increase in DN T cell number may be sufficient to confer resistance to

211 pression (IFN-gamma, STAT-1, granzyme B) and T cell numbers may be due to a reduction in DC-mediated

212 We found that despite normal T cell numbers, mice deficient in the costimulatory mole

213 n the compound knockout, although peripheral T cell numbers mirrored Flt3l(-/-) mice.

214 the precursor B-cell development, low B- and T-cell numbers, normal immunoglobulin gene use, limited

215 s contributed to the low OVA-specific CD8(+) T cell numbers observed during type I infection.

216 erations in cytokine expression, the reduced T-cell numbers observed coincided with diminished T-cell

217 hat despite a reduction in peripheral CD8(+) T cell numbers of ~50% in MHCI hemizygous mice, MHCI lev

218 tumor efficacy, without affecting responding T cell number or cytokine profile.

219 ase states that result in deficits in CD4(+) T cell numbers or function, such as may be seen in human

220 ant change in mucosal effector or regulatory T cell numbers or IL-10 mRNA expression.

221 on from diabetes did not result from altered T cell numbers or subset distributions, or regulatory/su

222 class I antigen presentation or diminish CD4 T-cell numbers or impair their function.

223 elated T-cell expansions do not impair naive T-cell numbers or maintenance of protective responses ag

224 o infection, and did not increase memory CD8 T cell numbers over those observed in wild-type controls

225 a significant increase in thymic and splenic T cell number (p < 0.05; p < 0.01).

226 HIV coinfection significantly increased T cell numbers (P = 0.017) and shifted cells from an int

227 ects, with significant differences in CLA(+) T-cell numbers (P < .01).

228 ma, demonstrating an increase in circulating T cell numbers, particularly naive (TREC+) T cells.

229 t lesion macrophage-positive area and CD4(+) T-cell number per lesion area, but reduced lesion expres

230 By contrasting Vgamma2Vdelta2 T-cell numbers, phenotype, and T-cell receptor (TCR) rep

231 derived cytokines in serum/plasma), reduced T cell numbers/proliferation, and TH1 skewing.

232 CD8(+) T cell-numbers rapidly expand and then contract after ex

233 We recently showed that blood CD4(+) T-cell numbers rapidly increase after dUCBT, and early C

234 occurs as HIV viremia is suppressed and CD4 T cell numbers recover.

235 lls, but showed no differences in regulatory T-cell numbers relative to patients without IRAEs.

236 plantation in rATG-treated patients, whereas T-cell numbers remained stable in both control groups.

237 ilamentous bacteria (SFB) partially restored T cell numbers, suggesting that SFB and other MMb organi

238 OVA-specific CD8 T cell number, TCR affinity, effector function, and infi

239 D4 T cells is controlled more tightly by CD4 T cell numbers than is CD8 T cell proliferation.

240 taining elevated insulin-specific regulatory T cell numbers that efficiently lowered diabetogenic eff

241 Because this transgene restores NK T cell numbers, the lack of secondary lymphocyte activat

242 apy stimulated significant increases in CD8+ T cell numbers, the number of CD4+ T cells remained unch

243 roliferation does not normally fully restore T-cell numbers, the CD8(+) T-cell pool was completely re

244 We prospectively measured T-cell numbers, thymopoiesis, and T-cell memory in 73 ch

245 , leading to reductions in pathologic DC and T-cell numbers to nonlesional levels; and (3) inhibition

246 Efficient boosting of memory T-cell numbers to protective levels generally requires a

247 thogen exposure, increased pathogen-specific T cell numbers together with altered migratory patterns

248 Although T cell numbers ultimately reached adult levels in the in

249 had a 60-fold increase in CD4(+)IFN-gamma(+) T cell numbers versus control animals at 2 wk post-needl

250 r gene-reporter probe systems for imaging of T cell number was performed, and the hNET/(18)F-MFBG PET

251 hanistically, we showed that the increase in T cell numbers was associated with superior tissue homin

252 The normalization of T cell numbers was due to inhibition of expansion of con

253 iter for all antigens, and decreasing CD4(+) T cell numbers was strongly associated with a decrease i

254 However, cervical CD4+ T-cell number was associated with HSV-2 infection and a

255 The reduction in T-cell number was marked by low expression of the antiap

256 the physiological age-related decline of the T-cell number was slower in pDGS patients compared with

257 in the percentage of CD4+ and CD8+ cells and T-cell numbers was observed in 48%, 71% and 99% of LTRs.

258 ddition to a significant diminution of naive T-cell numbers, we found impaired development of a diver

259 CD8(+), CD4(+), and gammadelta T cell numbers were also lower in the lungs of PVM-infec

260 Follicular T cell numbers were correlated with the number of B cell

261 In addition, memory T cell numbers were decreased in modified avian influenz

262 -specific CD8(+) T cells, but overall CD8(+) T cell numbers were either unaffected or only mildly inc

263 IL-17+ T cell numbers were higher in patients with extended oli

264 a.c. of TCR-transgenic OT-I mice, and CD8(+) T cell numbers were increased within eyes, suggesting th

265 ficantly protected from infection and CD4(+) T cell numbers were maintained in both the blood and the

266 In contrast, effector CD4(+) T cell numbers were not affected by the individual or co

267 gnificant effects on CD8(+) or CD4(+) memory T cell numbers were observed.

268 tic cells decreased in blood, whereas NK and T cell numbers were only marginally altered during the c

269 Intratumoral gammadelta T cell numbers were positively correlated with advanced

270 he adult Foxn1Delta/Delta thymus, peripheral T cell numbers were reduced only 10-fold.

271 but single-positive thymocyte and peripheral T cell numbers were reduced, reflecting a T cell-autonom

272 rs, whereas total cell, lymphocyte, and CD4+ T cell numbers were reduced.

273 t was normal in both strains, but peripheral T cell numbers were significantly decreased in DKO mice.

274 CD8(+) T cell numbers were significantly increased in eyes of m

275 By 7 wk, colitis score and colon CD4(+) T cell numbers were similar in Cre(+) and Cre(-) mice de

276 ted and cytokine-producing CD4(+) and CD8(+) T cell numbers were still significantly reduced 1 wk lat

277 ma in whom bronchoalveolar lavage regulatory T-cell numbers were also reduced.

278 CD4(+)CD25(+)Foxp3(+) regulatory T-cell numbers were decreased in the spleens of IL-13 KO

279 CD4(+) IL-17-producing T-cell numbers were diminished.

280 ontrol subjects, but decreases in CLA(+) TH1 T-cell numbers were greater in children with AD (17% vs

281 Furthermore, CD28(null) CD8 T-cell numbers were increased in Amish children, with hi

282 IL-10 levels and regulatory T-cell numbers were lower in the intestines of Tpl2(-/-)

283 At 6 months after transplantation, T-cell numbers were lower than before transplantation in

284 At baseline, naive CD4+ T-cell numbers were lower than naive CD8+ T-cell numbers

285 Although their B- and T-cell numbers were normal, they had low regulatory T-ce

286 Naive and central memory T-cell numbers were not affected, nor were anti-tetanus

287 Decreases in DC and T-cell numbers were observed after weeks 1 and 2, respec

288 Both Foxp3(-) and Foxp3(+) pMHCII-specific T-cell numbers were reduced in mice expressing the antig

289 Natural killer cell and CD4 and CD8 T-cell numbers were significantly reduced in treated ani

290 that regardless of transplant type, overall T-cell numbers were similar, although a faster rate of T

291 icient (CD45KO) mice have reduced peripheral T cell numbers where CD8 T cells are underrepresented.

292 reduction of NK cell (90% from baseline) and T-cell numbers whereas CD8 effector memory T-cell popula

293 f thymocytes and slightly reduced peripheral T cell numbers, whereas B cell-specific deletion of FADD

294 ad significantly reduced NK, NKT, and CD8(+) T cell numbers, whereas rIL-15/IL-15Ralpha restored thes

295 ad significantly increased Gag-specific CD8+ T cell numbers, whereas total cell, lymphocyte, and CD4+

296 ial thymus recovery and boosts donor-derived T cell numbers, which correlates with increased adhesion

297 a1(M6) allele developed normal thymocyte and T cell numbers with all expressing Vbeta14.

298 sitive association of CD4(+)CD25(+) FoxP3(+) T cell numbers with allergic sensitization (P = 0.05) an

299 atous lesions, while a correlation of IL-17+ T cell numbers with tenascin C-expressing cells and MMP-

300 e of IL-10 resulted in enhancement of CD8(+) T cell numbers without detectable alterations in the kin