ライフサイエンスコーパス: T-cell proliferative response

1 1 expression was associated with an impaired T cell proliferative response.

2 63, that generated a low-level but clear-cut T cell proliferative response.

3 -gamma, TNF-alpha, and IL-6 in the augmented T cell-proliferative response.

4 mus nor everolimus could inhibit the CD4CD28 T-cell proliferative response.

5 ing a significant HER-2/neu protein-specific T-cell proliferative response.

6 atory mediators, and failed to induce robust T cell proliferative responses.

7 ed by significant adaptive CD4(+) and CD8(+) T cell proliferative responses.

8 remia was not associated with an increase in T cell proliferative responses.

9 ent spleen APC in vitro leads to normal CD4+ T cell proliferative responses.

10 ther, mIEC did not inhibit splenic alphabeta T cell proliferative responses.

11 cant reduction in both MBP- and PLP-specific T cell proliferative responses.

12 ntly suppressed allogeneic CD4(+) and CD8(+) T cell proliferative responses.

13 the potency of APCs and boost mitogen-driven T-cell proliferative responses.

14 re involved in the ability of FDC to inhibit T-cell proliferative responses.

15 for antibody binding and induction of human T-cell proliferative responses.

16 accompanied by diminished antigen-specific, T-cell proliferative responses.

17 eral blood lymphocytes and better priming of T-cell proliferative responses.

18 llergic subjects but did not change in vitro T-cell proliferative responses.

19 hanges paralleled reduced IL-2 secretion and T cell proliferative responses after TCR-CD28 stimulatio

20 construct produced antibodies and exhibited T-cell proliferative responses against core or envelope.

21 The frequency of T-cell proliferative responses against VP2 was significa

22 significantly increased autoantigen-induced T cell proliferative responses along with greater number

23 tion of innate immune responses and adaptive T cell proliferative responses, along with only transien

24 ptides containing these sequences stimulated T cell proliferative responses, although less intensely

25 decreased its effectiveness in costimulating T cell proliferative response and early IL-2 production

26 The in vitro splenic T cell proliferative response and induction of IFN-gamma

27 s characterized by antigen-specific impaired T cell proliferative responses and a distinct pattern of

28 ice treated with recombinant Map had reduced T cell proliferative responses and a significantly reduc

29 Primary T cell proliferative responses and cytokine production (

30 ing that anti-TNF treatment in vivo enhances T cell proliferative responses and cytokine production p

31 as significant levels of OVA-specific CD4(+) T cell proliferative responses and OVA-induced IFN-gamma

32 ion, significant levels of OVA-specific CD4+ T cell proliferative responses and OVA-induced IL-4 and

33 In the mucosa, both Peyer's patch T cell proliferative responses and OVA-specific fecal Ig

34 Although we found both a high CD4(+) T cell-proliferative response and TH2 cytokines producti

35 fold increase in the median p24-induced CD4+ T-cell proliferative response and a 57% increase in the

36 on of E4 and E1 had little impact on the CD4 T-cell proliferative response and cytolytic activity of

37 compared with Ab positivity, we assessed the T-cell proliferative responses and Ab responses (islet c

38 ograft histopathology as well as anti-HLA-A2 T-cell proliferative responses and anti-HLA-A2 antibody

39 Allogeneic C3H/HeJ (C3H; H2k) T-cell proliferative responses and generation of cytotox

40 T-cell proliferative responses and immunoglobulin G anti

41 neration of T-regulatory cells that suppress T-cell proliferative responses and induce tolerance.

42 pulsed DC can induce both E7-specific CD4(+) T-cell proliferative responses and strong CD8(+) CTL res

43 Ex vivo grass antigen-driven T-cell proliferative responses and the frequency of IL-4

44 A and/or SRL both in vitro (by inhibiting of T-cell proliferative response) and in vivo (by inhibitin

45 -specific intrahepatic and peripheral CD4(+) T cell proliferative responses, and cytokines (enzyme-li

46 ion of maturation markers, IL-12 production, T cell proliferative responses, and IFN-gamma production

47 noglobulin A (IgA)- and IgG-secreting cells, T-cell proliferative responses, and gamma interferon sec

48 They elicited only weak allogeneic T-cell proliferative responses, and repeated stimulation

49 nt enhancement in anti-CD3-stimulated CD4(+) T-cell proliferative responses, and this proliferation w

50 The results suggest that HHV-8 T cell proliferative responses are common in HIV-negativ

51 n present on the surface of donor DCs, donor T cell proliferative responses are generated only in res

52 HIV-1-specific CD4+ T cell proliferative responses are not measurable in mos

53 allergen-driven IL-4(+) CD4(+) T cells, and T-cell proliferative responses are detectable in the per

54 T-cell proliferative responses are inhibited during the

55 The CD4+ inflammatory T cell proliferative responses as well as CD8+ CTL activ

56 ion significantly increased the CEA-specific T-cell proliferative responses as well as the cytolytic

57 key positions induced enhanced specific CD4+ T cell proliferative responses at lower peptide concentr

58 was negatively associated with HBV-specific T-cell proliferative responses at both time points.

59 ogeneic MLRs between DCs and T cells reduced T cell proliferative responses but did so less efficient

60 type, fail to mount a detectable FV-specific T-cell proliferative response but nevertheless produce F

61 or necrosis factor alpha failed to block the T cell proliferative responses, but anti-IL-2 was strong

62 stimulatory activity for primary and memory T-cell proliferative responses, but this was substantial

63 acterized by a lack of virus-specific CD4(+) T-cell-proliferative responses, but strong responses hav

64 n monocyte (MO) cultures inhibited mitogenic T cell proliferative responses by > 95%.

65 Suppression of CD4(+) T cell proliferative responses by both CD25(+) and CD25(

66 pse formation prior to the induction of full T cell proliferative responses by concurrent indirect Ag

67 atory T cells that more efficiently suppress T cell proliferative responses by mixed leukocyte reacti

68 -shock-protein peptides elicited significant T-cell proliferative responses by the gamma delta subset

69 pid TM-mediated responses to PECs but induce T-cell proliferative responses characterized largely as

70 lls showed enhanced suppressive activity for T cell proliferative responses compared with freshly iso

71 cells, B cells, or natural killer cells, or T-cell proliferative response compared with interferon b

72 H/K ATPase-specific T cell proliferative responses could first be detected 5

73 Suppression of T cell-proliferative responses during malaria has been a

74 demonstrated CMV-specific CD4(+) and CD8(+) T cell proliferative responses from PBMC, with CD4(+)IFN

75 5-284, 295-314, and 305-324) elicited strong T-cell proliferative responses from all strains of mice

76 more, both the magnitude of p24-induced CD4+ T-cell proliferative responses from CD8-depleted PBMC an

77 These p24-induced CD4+ T-cell proliferative responses from CD8-depleted PBMC we

78 Our results suggest that the inhibition of T cell proliferative response in microgravity culture is

79 -beta fusion cells failed to induce a strong T cell proliferative response in vitro, mainly due to th

80 HIV-1 Ag-specific CD4(+) T cell proliferative responses in human subjects with ad

81 d the CTLp frequency, anti-NP Ab titers, and T cell proliferative responses in mice that were injecte

82 alf-life becomes apparent during analyses of T cell proliferative responses in mice, particularly whe

83 The inhibitory activity of GR1 reduced T cell proliferative responses in MLR and induced Ag-spe

84 tion of cell cycle progression and sustained T cell proliferative responses in naive T cell populatio

85 t epitope, peptide 5 (P5), stimulates strong T cell proliferative responses in subjects with delayed

86 and TILN immunization induced specific CD4+ T cell proliferative responses in the iliac lymph nodes,

87 munization with this construct elicited CD4+ T cell proliferative responses in vivo.

88 ryptophan (1-mT) results in increased CD4(+) T-cell proliferative response in PBMCs from HIV-infected

89 Interestingly, most HCV-specific CD4 T-cell proliferative responses in AA patients were unacc

90 T-cell proliferative responses in individuals older than

91 The peptide also induced LT-B-specific T-cell proliferative responses in these mice.

92 nerally marked, but temporary suppression of T-cell proliferative responses in vitro to phytohemagglu

93 a low level of immunogenicity; (4) decreased T-cell proliferative responses in vitro, and (5) did not

94 Like C1q, HCV core can inhibit T-cell proliferative responses in vitro.

95 ulsing of DC to efficiently trigger specific T-cell proliferative responses in vitro.

96 Human HSCs did not stimulate allogeneic T-cell proliferative response, indicating that they are

97 CD4(+) T-cell proliferative responses indicative of breakdown o

98 inally, both internalization of CD26 and the T cell proliferative response induced by CD26-mediated c

99 CMX-13 inhibited T cell proliferative responses induced by Con A and allo

100 The peripheral blood T cell proliferative responses induced by topo I and in

101 tablished in male mice: ZP3 peptide-specific T cell proliferative response is reduced and AOD is abse

102 The results suggest that a strong T-cell proliferative response is induced upon rechalleng

103 st dose levels of vaccine, peptide-specific, T-cell proliferative responses (n = 3) and/or DTH respon

104 The enhancement of virus-specific T cell proliferative responses observed in vitro with si

105 T cell proliferative responses of B6.129S1-IL-12rb2(tm1J

106 cell deficiency did not significantly alter T cell proliferative response or cause a shift in the Th

107 and inguinal lymph nodes, without affecting T cell proliferative responses or levels of anticollagen

108 ELISpot and T-cell proliferative responses peaked at day 14 and 28 a

109 gammaRIIB only modestly affected initial CD4 T cell proliferative responses, suggesting that FcgammaR

110 s anergy to recall antigens and lower (<70%) T-cell proliferative responses than controls after activ

111 te resulted in abrogation of hapten-specific T cell proliferative responses that correlated with dimi

112 ood of infected individuals, inhibited human T cell proliferative response through interaction with t

113 d dendritic cell responses (flow cytometry), T-cell proliferative responses (thymidine incorporation)

114 ll peptide tolerance suppressed the in vitro T cell proliferative response to AChR and its dominant a

115 Functionally, Linc00402 augmented the T cell proliferative response to an allogeneic stimulus

116 bodies against HCV pseudotype virus, a B and T cell proliferative response to antigens, and improved

117 h wild-type C57BL/6 mice and had an enhanced T cell proliferative response to bovine CII.

118 As little as 5 microM PAHA led to a 10-fold T cell proliferative response to chromatin in short term

119 line viral load or CD4+ T cell count and the T cell proliferative response to HIV-1 Gag.

120 iciency only partially reduced the naive CD8 T cell proliferative response to IL-15/IL-15Ralpha compl

121 was associated with a significantly reduced T cell proliferative response to mycobacterial Hsp65, wh

122 eduction in EAE correlated with a diminished T cell proliferative response to myelin basic protein in

123 fected with T. gondii developed a gammadelta T cell proliferative response to parasite Ag.

124 secretion and were unable to induce a normal T cell proliferative response to TT.

125 h lowered serum autoantibody levels, reduced T cell proliferative responses to AChR, and an expansion

126 e immunocompromised, with reduced polyclonal T cell proliferative responses to alloantigen, defined p

127 cell functions including IL-2 secretion and T cell proliferative responses to CD28 plus T cell recep

128 Assays were performed to study T cell proliferative responses to CII in peripheral bloo

129 T cell proliferative responses to diabetes-associated Ag

130 We compare changes in lymphocyte subsets, T cell proliferative responses to disease-associated tar

131 The induction of CD4+ T cell proliferative responses to eight synthetic peptid

132 oviding sufficient help to allow optimal CD8 T cell proliferative responses to exosomal protein.

133 First, neither APC type was able to initiate T cell proliferative responses to full-length native Top

134 The human T cell proliferative responses to GA were HLA class II D

135 and untreated MS patients exhibit prominent T cell proliferative responses to GA.

136 It has been suggested that CD4+ T cell proliferative responses to HIV p24 Ag may be impo

137 helper lymphocytes, manifested by increased T cell proliferative responses to HIV-1 Gag and recall a

138 owever, it has been difficult to demonstrate T cell proliferative responses to human insulin in IDDM

139 n of 25 tested persons made antigen-specific T cell proliferative responses to L2E7, and peripheral b

140 IL-12 significantly increased PBMC and CD4+ T cell proliferative responses to p24 Ag in HIV-infected

141 T cell proliferative responses to purified HHV-8 were me

142 bioavailability facilitated the induction of T cell proliferative responses to suboptimal stimuli.

143 Primary T cell proliferative responses to TCR ligation plus CD28

144 Eleven of the 21 patients also developed T cell proliferative responses to the homologous self-Ag

145 CD4 T cell proliferative responses to the pneumococcal prote

146 Abs, inhibition of SIV replication, and CD4+ T cell proliferative responses to three of the extracell

147 T cell proliferative responses to topo I were detected i

148 row also had a reduced capacity to stimulate T cell proliferative responses to tubercle bacillus Ag 8

149 validated linear discriminant analysis using T cell proliferative responses to two regions of Tri r 2

150 immunization, respectively), in increases in T cell-proliferative response to HPV-16 L1 VLPs (P<.001)

151 lerosis, but had no inhibitory effect on the T cell-proliferative response to myelin basic protein (M

152 T cell-proliferative responses to a single epitope, HEL4

153 ient than untreated DCs in driving syngeneic T cell-proliferative responses to staphylococcal enterot

154 In addition, the T-cell proliferative response to allogeneic LC-derived m

155 of T-cell tolerance was assessed by splenic T-cell proliferative response to antigen at 5 weeks.

156 protective effect is associated with reduced T-cell proliferative response to B-(9-23) in B-(9-23)-tr

157 The T-cell proliferative response to HBcAg did not differ be

158 l but two patients made primary antibody and T-cell proliferative responses to a foreign antigen admi

159 L-17 receptor (R):Fc fusion protein inhibits T-cell proliferative responses to alloantigens and prolo

160 rom four different colonies side-by-side for T-cell proliferative responses to an expanded panel of a

161 nfiltration into grafts but not with altered T-cell proliferative responses to donor stimulators.

162 R-/- --> F1 chimeras were also able to mount T-cell proliferative responses to foreign antigens equal

163 T-cell proliferative responses to HER-2/neu peptides and

164 A range of T-cell proliferative responses to HPV-11 VLP were observ

165 ulin, saliva IgA binding to insulin, or CD4+ T-cell proliferative responses to insulin were observed

166 and saliva IgA binding to insulin, and CD4+ T-cell proliferative responses to insulin.

167 After the transplantation of thymus tissue, T-cell proliferative responses to mitogens developed in

168 All 7 survivors developed T-cell proliferative responses to mitogens of more than

169 T-cell proliferative responses to SIV gp140 and T-helper

170 T-cell proliferative responses to synthetic peptides dem

171 Considerable heterogeneity in the T-cell proliferative responses to these three variant an

172 as detected by inhibition of the Ag-specific T cell proliferative response upon Ag presentation by IF

173 bility to enhance anti-CD3-stimulated CD4(+) T cell proliferative responses via B7-1 and B7-2.

174 gnificant revival of antigen specific CD4(+) T cell proliferative response was observed after reconst

175 dendritic cells (DCs) to induce Ag-specific T cell proliferative responses was significantly reduced

176 r ability to transduce CLL cells, a vigorous T-cell proliferative response was obtained using cells t

177 well as anti-HLA-A2 antibody development and T cell proliferative responses were determined at days +

178 en delayed-type hypersensitivity and splenic T cell proliferative responses were examined, Peyer's pa

179 persistent, and vigorous HIV-1-specific CD4+ T cell proliferative responses were present, resulting i

180 T cell proliferative responses were seen with all enceph

181 Furthermore, specific CD4(+) and CD8(+) T cell proliferative responses were significantly increa

182 In these animals, MOG-specific T cell proliferative responses were transiently suppress

183 mature DCs were used to stimulate allogeneic T cells, proliferative responses were dampened (approxim

184 fied subsets of lymphocytes and quantitative T-cell proliferative response were assessed in an explor

185 her neutralizing antibodies nor SIV-specific T-cell proliferative responses were detectable in any of

186 troy islet tissue in vivo though spontaneous T-cell proliferative responses were observed in prediabe

187 he sole class II molecule generated a robust T cell-proliferative response when primed with peptide 2

188 l newborn blood specimens tested also showed T cell proliferative responses, which included a marked

189 ith specific impairment of ex vivo antidonor T cell proliferative responses, which was not reversed b

190 These data suggest that Ply induces CD4 T cell proliferative responses with production of IFN- g

191 the absence of strong HIV-1-specific, CD4(+) T-cell-proliferative responses, yet the mechanism underl