ライフサイエンスコーパス: T-cell subset

1 ectively constitute the most abundant memory T cell subset.

2 are, effector memory CD4(+)CXCR5(hi)CD32(hi) T cell subset.

3 I-restricted CD8+ T cells represent a unique T cell subset.

4 ted to a resting PD1(+)ICOS(-) CD4(+) memory T cell subset.

5 s are a unique unconventional thymic-derived T cell subset.

6 he last few years as a potent unconventional T cell subset.

7 amma-producing CD27(+) Vgamma4(+) gammadelta T cell subset.

8 eta-cell function and extended this to other T cell subsets.

9 K, and PLC) were similarly activated in both T cell subsets.

10 were also found in multiple different CD4(+) T cell subsets.

11 e the generation of proinflammatory effector T cell subsets.

12 lowered PD-1 expression in naive and memory T cell subsets.

13 bolism, which was distinct from other CD8(+) T cell subsets.

14 with the effector functions of other CD4(+) T cell subsets.

15 subsets, akin to T(H)1/2/17 conventional CD4 T cell subsets.

16 elper T cells, regulatory T cells, and other T cell subsets.

17 inally differentiated KLRG1(hi) effector CD8 T cell subsets.

18 which have revealed striking similarities to T cell subsets.

19 nd plasma cell numbers, and normalized B and T cell subsets.

20 esent important differences among gammadelta T cell subsets.

21 s that are functionally analogous to diverse T cell subsets.

22 e the entire spectrum of memory and effector T cell subsets.

23 entially regulating gene expression in these T cell subsets.

24 so revealed no defects in the development of T cell subsets.

25 undergoes differential methylation in CD8(+) T cell subsets.

26 the ex vivo response to S1P of primary human T cell subsets.

27 ave the capacity to regulate the function of T cell subsets.

28 and S1PR2 governs the migratory behavior of T cell subsets.

29 ecific tumor-infiltrating exhausted-like CD8 T cell subsets.

30 as intermittently detected from various CD4+ T cell subsets.

31 nd preventing its conversion to other CD4(+) T cell subsets.

32 exhibited oligoclonal expansion of specific T cell subsets.

33 luminate bioenergetic derangements of ME/CFS T cell subsets.

34 tive receptor on naive B cells and activated T cell subsets.

35 ide valuable insights into the adaptation of T cell subsets.

36 led to decreased PD-1 expression on certain T cell subsets.

37 ndicator of Notch signaling across activated T cell subsets.

38 n genomic DNA extracts from different CD4(+) T cell subsets.

39 edented mechanisms of control for gammadelta T cell subsets.

40 d propose a new approach for defining memory T cell subsets.

41 th IL-17- and IFN-gamma-producing gammadelta T cell subsets.

42 Flow cytometry was used to characterize T-cell subsets.

43 ges in these and other potentially senescent T-cell subsets.

44 t affect the differentiation of other CD4(+) T-cell subsets.

45 ndependently impacted on multiple B-cell and T-cell subsets.

46 e highest expression on naive CD4 and CD8(+) T-cell subsets.

47 not a result of proportional aberrations of T-cell subsets.

48 function of individually sorted CAR-modified T cell subsets after activation with CD3 and CD28 Abs (C

49 eration and reactivation of different memory T cell subsets after transplantation.

50 and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. sterc

51 ostly additive effects on the frequencies of T cell subsets along with unique modulation of terminall

52 tinct TCR-defined IL-17-producing gammadelta T cell subsets also exist in humans, but unlike the mous

53 t studies have identified a unique stem-like T-cell subset amongst exhausted CD8-positive T cells in

54 ion is altered in DLB compared with AD, with T cell subset analysis supporting a possible shift towar

55 s represent the main innate human gammadelta T cell subset and dominate the fetal and adult periphera

56 of VISTA disrupted the major quiescent naive T cell subset and enhanced self-reactivity.

57 were manufactured from defined CD4+ and CD8+ T cell subsets and administered in a defined CD4+:CD8+ c

58 R6(-), and gammadelta27(-)CCR6(+) gammadelta T cell subsets and alphabeta T cells.

59 or entry, which may direct SIV toward CD4(+) T cell subsets and anatomical sites that support viral r

60 ncouples the relationship between changes in T cell subsets and beta-cell function that is a componen

61 -promoter interactions in rare primary human T cell subsets and coronary artery smooth muscle cells l

62 nition of DENV-specific activated human CD8+ T cell subsets and defines a benchmark profile that vacc

63 , reveal distinct circulating CD4(+)CXCR5(+) T cell subsets and demonstrate oral fluid sampling for i

64 letional roles for Nur77 that differ between T cell subsets and have implications for self-tolerance.

65 ing to exert divergent effects across CD4(+) T cell subsets and highlight specific roles for this pat

66 ic processes control the function of various T cell subsets and how these metabolic processes are alt

67 CD8 T cell subsets and phenotypes were assessed by flow cyto

68 eate developmental trajectories of alphabeta T cell subsets and refine the kinetic selection model of

69 s chromatin regulators of therapy-responsive T cell subsets and reveals a shared regulatory program t

70 cifically released by different human CD4(+) T cell subsets and started to unveil the potential use o

71 arises from the specialization of different T cell subsets and the plasticity of individual naive T

72 As our appreciation of different T cell subsets and their plasticity increases, the initi

73 iring the capacity of DC to activate several T cells subsets and potentially conferring C. albicans,

74 reement between RNA sequencing estimation of T-cell subset and pathologist-determined TIL score.

75 of proviral sequences within individual CD4 T-cell subsets and across tissue compartments.

76 here, integrates the activities of distinct T-cell subsets and by definition is dynamic and responsi

77 nt relationships between HIV persistence and T-cell subsets and chemokines in rectal and LN tissue su

78 gression models evaluated the association of T-cell subsets and diabetes stratified by HIV status, ad

79 associated with specific clusters of memory T-cell subsets and lower frequencies of HCMV-specific mu

80 rially analyzed peripheral blood CD8 and CD4 T-cell subsets and monitored for the development of de n

81 and/or enzyme-linked immunosorbent assay in T-cell subsets and PBMCs from patients with asthma and a

82 Analysis of CD4(+) T-cell subsets and TCR variable beta classes from health

83 s the functional properties of each expanded T cell subset, and paves the way for a more detailed eva

84 parent cells by reducing the infiltration of T cell subsets, and other inflammatory cells, in the eye

85 ph nodes, bone marrow, CSF, circulating CD4+ T cell subsets, and plasma.

86 more pronounced for CD4 T cells than for CD8 T cell subsets, and was dependent on S1PR2, as shown usi

87 T cell subsets are critically involved in the developmen

88 experienced subsets decrease, whereas CD8(+) T cell subsets are relatively resistant to drug effects,

89 metabolic programs of functionally distinct T cell subsets are tailored to their immunologic activit

90 ses of distinct pro-inflammatory CD4 and CD8 T cell subsets, as well as Treg function, in paediatric-

91 TCR alpha and beta repertoire sequencing for T-cell subsets, as well as single-cell RNAseq and TCRseq

92 The CD4+ and CD8+ T-cell subsets associated with diabetes are similar in P

93 in human CD4(+) and CD8(+) naive and memory T cell subsets at greater resolution using polychromatic

94 Deep profiling identified 2 central memory T cell subsets at onset and 5 terminally differentiated

95 subsets, naive and memory phenotype of each T-cell subset, B cells, and natural killer cells.

96 that chronic opioid use alters human CD8(+) T cell subset balance, with notable decreases in T effec

97 or (TCR) sequences, enable us to identify 11 T cell subsets based on their molecular and functional p

98 d CD8(+) T cells, nor in any of these CD4(+) T cell subsets between groups.

99 jor regulators of human and mouse gammadelta T cell subsets, but considerable contention surrounds wh

100 ly correlated with PDCD1, CTLA-4, and CD8(+) T-cell subset, but negatively correlated with tumor puri

101 hat DMF acts on specific memory and effector T cell subsets by limiting their survival, proliferation

102 s involving B cells and a specialized CD4(+) T cell subset called T follicular helper (Tfh) cells.

103 ction have defined a PD-1(+) Tcf-1(+) CD8(+) T cell subset capable of self-renewal and differentiatio

104 n contact maps, generated from primary human T-cell subsets (CD4(+) naive, T helper type 17, and regu

105 associated HIV RNA, residual plasma viremia, T-cell subsets, cell activation, and inflammation marker

106 help to shed light on how a range of CD4(+) T cell subsets come to harbor HIV DNA, which is one of t

107 /cirrhosis is associated with alterations in T-cell subsets consistent with immunosenescence.

108 T follicular helper (Tfh)-cell induction, a T-cell subset critically implicated in lymphoid organ fo

109 The discovery of CD4(+) T cell subset-defining master transcription factors and

110 okines and the relative proportion of memory T-cell subsets depending on Mtb infection status.

111 on-therapy plasmas and HIV-1 DNA from CD4(+) T cell subsets derived from peripheral blood (PB), lymph

112 has been shown to be important for promoting T cell subset development and function.

113 stablished but the dynamics of memory CD4(+) T cell subset development, their infectability and influ

114 ly, signaling downstream of PD-1 in purified T cell subsets did not correlate with PD-1 surface expre

115 Notably, other CD8(+)T-cell subsets did not exert a similar effect on overall

116 T-cell subsets dominated the cellular immune compartment

117 st completely derived from the stem-like CD8 T cell subset during established chronic LCMV infection.

118 t, specialities, and functions of gammadelta T cell subsets during cancer progression.

119 e sequencing is a powerful tool for tracking T cell subsets during disease.

120 d the core-2 O-glycoform of CD43 in multiple T cell subsets during graft-versus-host disease.

121 he composition and dynamics of the epidermal T-cell subsets during ACD are not known.

122 Notably, distinct traits in CD4(+) effector T cell subsets emerged when we focused on a subgroup of

123 These T-cell subsets exhibit different susceptibilities to the

124 substantial expansion of CD3(+)CD4(-)CD8(-) T-cell subset expressing Vdelta2 TCR was specifically ob

125 er effector T cells, expansion of regulatory T-cell subsets expressing CXCR3 or retinoic acid-related

126 To evaluate the CD8(+) T cell subsets, expression of inhibitory receptors, and

127 A new T-cell subset, follicular helper T (TFH) cells, is speci

128 rs; however, much less is known about CD4(+) T-cell subsets following vaccination.

129 Peak change in monocyte, B cell, and T cell subset frequencies coincided with peak virus shed

130 cell subsets and suggest that pre-treatment T-cell subset frequencies may have value in predicting F

131 Interestingly, the stem-like CD8 T cell subset from chronic infection, despite sharing ke

132 infection were strikingly different from CD8 T cell subsets from acute infection.

133 pared the epigenetic signatures of the 2 CD8 T cell subsets from chronically infected mice with effec

134 In contrast to control cells, T cell subsets from methadone users show decreased expre

135 regulatory and stem cell-like memory CD4(+) T cell subsets from patients with type 1 diabetes and he

136 CD4(+) T-cell subsets from 86 patients without T-cell lymphoma

137 We analyzed CD4(+) helper T-cell subsets from peripheral blood or cerebrospinal fl

138 Each T cell subset function (such as effector, helper, memory

139 Both CD8 T cell subsets generated during chronic infection were s

140 Blimp1 for homeostatic maintenance of these T cell subsets had not been investigated.

141 , differential regulation of adhesiveness in T cell subsets has not been explored yet.

142 However, many CD4(+) and CD8(+) T cell subsets have been described in the past.

143 Although CD4 T cell subsets have been mapped globally for numerous ep

144 It is realized that CD4(+) T cell subsets have different metabolic requirements.

145 programs associated with DENV-specific CD8+ T cell subsets have not been defined.

146 However, new T-cell subsets have not been considered.

147 of the latent HIV reservoir in memory CD4(+) T cell subsets identify LRAs that reverse latency with r

148 to define naive, effector, and memory CD8(+) T cell subsets, implying that they may be involved in fa

149 invariant T (MAIT) cells are an innate-like T cell subset important in the early response to bacteri

150 led to identify a nonredundant role for this T cell subset in experimental cerebral malaria (ECM).

151 invariant T (MAIT) cells are an innate-like T cell subset in mammals that recognize microbial vitami

152 the extent of induction of the inflammatory T cell subset in vitro that mainly drives lesions, but n

153 transplant, the composition of memory CD8(+) T cell subsets in blood improved prediction of 8-year ki

154 against tumor, but the role of human CD4(+) T cell subsets in cancer immunotherapy remains ill-defin

155 -1) persists as a latent reservoir in CD4(+) T cell subsets in central memory (T(CM)), transitional m

156 DENV-specific CD8+ T cell subsets in general, and Temra cells in particular

157 at(+)T-bet(lo)PLZF(-) iNKT and gammadelta-hi T cell subsets in healthy peripheral blood.

158 of monocytes, neutrophils, B lymphocytes and T cell subsets in lymphoid or mucosal sites did not vary

159 , we tracked the generation of memory CD4(+) T cell subsets in mice housed in facilities differing in

160 We found both DN T cell subsets in normal and cancerous human kidneys, in

161 signalling underwrite the known function of T cell subsets in patients with SLE.

162 uggest that S1P promotes retention of memory T cell subsets in secondary lymphoid organs, via S1PR2.

163 utant Delta5G virus infected distinct CD4(+) T cell subsets in SLOs and the small intestine, respecti

164 R) sequencing to characterize unconventional T cell subsets in surgical lung resections and blood fro

165 The number and activity of T cell subsets in the atherosclerotic plaques are critic

166 results in alteration of dendritic cell and T cell subsets in the gut as well as loss of antigen-spe

167 gammadelta T lymphocytes, dominant T cell subsets in the intestine, mediate both regulatory

168 We found that conventional and regulatory T cell subsets in the thymus of neonates and young mice

169 Moreover, some T cell subsets in these plaques presented markers of T c

170 T cells subsets in blood, spleen and lymph nodes were de

171 riant T (MAIT) cells are a large innate-like T-cell subset in humans defined by invariant TCR Valpha7

172 CD8(+)CD28(-) T cells represent a pathogenic T-cell subset in SSc and likely play a critical role in

173 ory and inflammation related cell (IRC) CD4+ T-cell subsets in 705 individuals across the IA-continuu

174 -) ) "polar" CD4(+) and CD8(+) and activated T-cell subsets in AA vs atopic dermatitis (AD) and contr

175 )) "polar" CD4(+)/CD8(+) ratio and activated T-cell subsets in patients with vitiligo compared with p

176 However, the role of other T-cell subsets in pemphigus pathogenesis remained unclea

177 a study of skin lesions or activated CLA(+) T-cell subsets in peripheral blood.

178 entified 11 transcriptionally diverse CD8(+) T-cell subsets in psoriatic and healthy skin.

179 4 and PD-1 limit the induction of particular T-cell subsets in S. stercoralis infection, which sugges

180 T-cell subsets in T-cell receptor beta knockout mice wer

181 lowing secondary influenza infection, memory T-cell subsets in the lungs of obese mice were decreased

182 ese data hint for a possible role of diverse T-cells subsets in disease pathogenesis and emphasize th

183 jority of CD4(+) conventional and regulatory T cell subsets; in general, Ag-naive subsets increase an

184 lls and CD28(null) T cells, as well as other T cell subsets including CD8(+) T cells and gammadelta T

185 A reduction of peripheral T-cell subsets including regulatory T cells was observed

186 .C.CH505 DNA was detected in multiple CD4(+) T cell subsets, including cells with a naive phenotype (

187 Unconventional T cell subsets, including donor-unrestricted T cells (DU

188 quential differentiation to generate diverse T cell subsets, including major histocompatibility compl

189 iretroviral therapy (ART) in multiple CD4(+) T cell subsets, including naive cells, central memory (C

190 At T0, the frequencies of CD4 T cell subsets, including peripheral T follicular helper

191 Various T-cell subsets, including Th2/Th22 cells, are increased

192 tigated the frequency and function of CD8(+) T cell subsets-including effector memory (EM) and termin

193 models are skewed to an antigen-experienced T-cell subset, indicating a certain degree of antitumor

194 t Staphylococcus aureus, but the predominant T cell subsets involved are unclear.

195 ates the differentiation program of multiple T cell subsets involved in T1D development and may be su

196 Elucidation of distinct T-cell subsets involved in multiple sclerosis immune-pat

197 ased MHP was a general phenotype observed in T cell subsets irrespective of prior antigen exposure, a

198 es of human naive and effector/memory CD4(+) T-cell subsets, irrespective of antigen specificity.

199 ows that the repertoire of the exhausted CD8 T cell subset is almost completely derived from the stem

200 prove the principle that the Vgamma2Vdelta2 T cell subset is protective against Mycobacterium tuberc

201 developing tools to interrogate FA-uptake by T cell subsets is important for understanding tumor immu

202 ogical function of endogenous CD83 in CD4(+) T cell subsets is still unclear.

203 The homeostatic role of these gammadelta T cell subsets is to maintain barrier integrity and prev

204 cise molecular mediators that govern this in T cell subsets is unknown until now.

205 and phenotypically different between CD4(+) T cell subsets isolated from PLWH on suppressive ART (n

206 t CD151 could mark a phenotypically distinct T cell subset, it was not uniformly expressed on T cells

207 infected individuals by sorting memory CD4+ T-cell subsets lacking or expressing high levels of inte

208 ction of human natural killer (NK) cells and T cell subsets limit the applicability of humanized mice

209 a T cells, which were replaced by gammadelta T-cell subsets (mainly Vgamma6(+) gammadelta(low)CCR2(+)

210 ts the view that the dominant Vgamma2Vdelta2 T cell subset may be included in the rational design of

211 The study of this T-cell subset may lead to a better understanding on how

212 This super-functional T cell subset might be a superior driver of autoimmune p

213 Restoration of the antigen-specific CD4 T-cell subsets mirrored the overall CD4 T-cell compartme

214 included total T cells, helper and cytotoxic T-cell subsets, naive and memory phenotype of each T-cel

215 y clear that the terms used to define memory T cell subsets no longer accurately reflect our understa

216 In addition to conventional T cells, subsets of unconventional T cells exist, which

217 tified the relative effects of CD4+ and CD8+ T-cell subsets on bone.

218 IgE antibody in vivo in the absence of other T-cell subsets or even when TH2 cell functions were seve

219 ent understanding of the mechanisms by which T cell subsets orchestrate host resistance to Plasmodium

220 nsgenic mice, revealing evidence of multiple T-cell subset organ infiltration.

221 nced by a more complex model involving other T cell subsets, particularly Tregs.

222 elies on the disease-specific milieu driving T-cell subset polarization and autoantigen modifications

223 type 17, T helper type 22, and related CD8+ T-cell subsets producing IL-17A, IL-17F, and IL-22.

224 The dominant Vgamma2Vdelta2 T cell subset recognizes phosphoantigen and exists only

225 nuate regulatory but not conventional CD4(+) T-cell subsets [regulatory T cell (Treg) and conventiona

226 o data are available on whether human CD4(+) T cell subsets release EVs containing different pattern

227 ity to trans-differentiate into other CD4(+) T cell subsets remains mostly uncharacterized.

228 control the activity of metabolic enzymes in T cell subsets represents a promising endeavour in the s

229 gnaling for their development, but the exact T cell subset required had not been known.

230 We found PD-1(+) TRMs were the predominant T-cell subset responsive to anti-PD-1 treatment and sign

231 erminal effector versus memory-precursor CD8 T cell subsets showed that, rather than retaining a naiv

232 Different gammadelta T-cell subsets showing differential developmental and fu

233 ntly reported that a novel CXCR5IFN-gammaCD8 T-cell subset significantly inhibits posttransplant allo

234 -cell costimulation, which massively reduced T-cell subset skewing and exhaustion.

235 al previously unrecognized CD4(+) and CD8(+) T cell subsets strongly associated with a robust Ab resp

236 nsive expansion of highly cytotoxic effector T cell subsets, such as CD4(+) effector-GNLY (granulysin

237 V persistence.IMPORTANCE Long-lasting CD4(+) T cell subsets, such as central memory and stem cell mem

238 oming increasingly clear that unconventional T cell subsets, such as NKT, gammadelta T, mucosal-assoc

239 arametric and traditional manual analysis of T-cell subsets suggested a higher pre-treatment frequenc

240 es could also be detected in multiple CD4(+) T cell subsets, suggesting that infected cells can under

241 gs) uptake FA at a higher rate than effector T cell subsets, supporting the role of FA metabolism for

242 Here, we show that, among effector T cell subsets, Th17 and Treg cells selectively expresse

243 lls, thus collecting a broader response from T-cell subsets than QFT-GIT.

244 his study, we identified a unique gammadelta T cell subset that coexpresses high levels of gut-homing

245 ar regulatory T (Tfr) cells are a regulatory T cell subset that controls antibody production by inhib

246 he formation of a CX(3)CR1-expressing CD8(+) T cell subset that exhibited potent cytolytic function a

247 ll factor 1-positive (TCF1(+)) stem-like CD8 T cell subset that gives rise to the terminally differen

248 RM precursor cells represent a unique CD8(+) T cell subset that is distinct from the precursors of ci

249 we thus identified a new HBHA-induced CD4(+) T cell subset that may contribute to the control of M. t

250 ma6(+) T cells were a predominant gammadelta T cell subset that produced IL-17A as well as IL-22, TNF

251 licular helper (Tfh) cells are a specialized T cell subset that regulates the long-lived production o

252 d PD-1(hi)) that define a tumor-specific CD8 T cell subset that retain some functional capacity.

253 thus highlights the diversity of follicular T cell subsets that contribute to the breakdown of B-cel

254 ition of IL-17 would decrease the numbers of T cell subsets that function as B-cell helpers, as well

255 he mouse thymus produces discrete gammadelta T cell subsets that make either interferon-gamma (IFN-ga

256 eously study the responsiveness of different T cell subsets, that is, naive, effector, and memory T c

257 overy sheds new light on the biology of this T cell subset, their function during tumor immunity, and

258 n this Review, we summarize the knowledge on T cell subsets, their functions in atherosclerosis and t

259 Early involvement of effector T cell subsets thus points to a key role of T cells in M

260 ervations trace a detailed picture of CD4(+) T cell subsets tightly associated with IRIS, which may s

261 liferating gammadelta T cells were the first T cell subset to respond to MC-driven inflammation, and

262 issue of the JCI, Lee et al. evaluated CD4+ T cell subsets to determine whether certain populations

263 Differential responses of memory CD4(+) T cell subsets to latency-reversing agents (LRAs) demons

264 immune activation and loss of trafficking of T cell subsets to niches that sustain their maturation a

265 ndent recruitment and activation of multiple T cell subsets to the skin and draining lymph nodes (DLN

266 To investigate hepatic T-cell subsets upon hypercholesterolemia.

267 % of the TCR repertoire of the exhausted CD8 T cell subset was shared with the stem-like CD8 T cells.

268 Likewise, the adhesion of these T cell subsets was indistinguishable in the presence of

269 A higher expression level of CD8(+) T-cell subset was also associated with improved overall

270 genic CD8+ T cells (OT-I) CXCR5 or CXCR3 CD8 T-cell subsets was also investigated.

271 eir association with antiviral effector CD8+ T cell subsets were also characterized in lung infiltrat

272 The TCR repertoires of both CD8 T cell subsets were composed mostly of a few dominant cl

273 r expression revealed that thymic gammadelta T cell subsets were each marked by distinct coexpression

274 d (CXCR5CXCR3 and CXCR3CXCR5) alloprimed CD8 T-cell subsets were analyzed for in vitro cytotoxicity a

275 nsiveness (AHR), pulmonary inflammation, and T-cell subsets were assessed 24 hours after the last exp

276 Multiple CD4+ and CD8+ T-cell subsets were measured by flow cytometry, and prev

277 Cytotoxic responses of T-cell subsets were measured by using flow cytometry.

278 ecreased absolute counts of B cells and most T-cell subsets were seen on-treatment.

279 tuted by adoptive transfer with CD4+ or CD8+ T-cells subsets were reconstituted in T-cell receptor be

280 (TFs) are key to the development of specific T cell subsets, whether additional transcriptional regul

281 l latency control in different memory CD4(+) T cell subsets which harbor latent HIV in vivo and suppo

282 , migration and differentiation into diverse T cell subsets while also self-renewing.

283 es reflect activities of distinct gammadelta T cell subsets, whose origins offer interesting insights

284 s suggests the induction by HBHA of a CD4(+) T cell subset with cytolytic function, and as nearly hal

285 cating the presence of an underactivated CD8 T cell subset with regulatory capacity against late stag

286 Cytolytic CD8(+) T cell subsets with effector-like epigenetic and transcr

287 Collectively, these findings identify CD4(+) T cell subsets with properties critical for improving ca

288 Furthermore, a detailed analysis of T cell subsets with regard to their PD-1 and PD-L1 expre

289 ar circulation, whereas non-cytolytic CD8(+) T cell subsets with stem-like epigenetic and transcripti

290 -inducible phosphoepitopes demonstrates that T cell subsets with T21 show elevated levels of basal IF

291 for most immune-based therapies to succeed, T cell subsets with the correct tumor-targeting specific

292 differed markedly between cytokine-producing T cell subsets with, gamma interferon (IFN-gamma)- and t

293 Expansion of the CXCR3+PD1-/low CD8 T-cell subset with functional capacity and potential to

294 ion, treatment expanded a CXCR3+PD1-/low CD8 T-cell subset with the ability to secrete cytokines.

295 Multiple memory CD8(+) T-cell subsets with distinct functional and homing chara

296 esence of functional effector and regulatory T-cell subsets with diverse T-cell receptor clonotypes i

297 but it remains unclear whether CD4-positive T-cell subsets with similar features exist in chronic in

298 es are the major human peripheral gammadelta T cell subset, with broad reactivity against stressed hu

299 is affected by the balance of different CD4 T cell subsets, with greater severity occurring when the

300 e proliferation of a Vdelta2(neg) gammadelta T-cell subset within peripheral blood mononuclear cells