ライフサイエンスコーパス: T4 phage

1 amily and is one of three helicases found in T4 phage.

2 9 pol L561A, with either mutant or wild-type T4 phage.

3 crease the spontaneous mutation frequency of T4 phage.

4 eviously for acridine-induced frameshifts in T4 phage.

5 icantly improves the genomic editing rate of T4 phages.

6 kDa domain of RecB to the gene 32 protein of T4 phage, a ssDNA binding protein that does not have str

7 We show that T4 phage adhesin binds E. coli B LPS in its native or de

8 As previously reported for T4 phage aerobic rNDP reductase, we found the relative a

9 Interestingly, the costs of building a T4 phage and a single influenza virus are nearly the sam

10 r increasing the encounter rates between the T4 phage and E. coli bacteria.

11 cumulation and persistence of mucus-adherent T4 phage and nonadherent T4hoc phage in the mucus.

12 rces for the interaction between hydrophobic T4 phages and hydrophobic C. cinerea surfaces.

13 logues, P. aeruginosa AlgQ, E. coli Rsd, and T4 phage AsiA, all induced mucoidy, suggesting that redu

14 encoding the L561A variant of RB69 pol with T4 phage bearing a mutant rII locus, and the rates of re

15 arge DNA viruses of eukaryotic and bacterial T4 phages but not to those of eubacteria.

16 The T4 phage capsid accessory protein genes soc and hoc have

17 In T4 phage, coordinated leading and lagging strand DNA syn

18 noparticles were functionalized with mSA-Hoc T4 phage demonstrated in an E. coli detection assay with

19 The glucosylation of T4 phage DNA is part of a phage DNA protection system ai

20 loped to clone linear DNAs by overexpressing T4 phage DNA ligase in vivo, based upon recombination de

21 static character is observed between Hjc and T4-phage endonuclease VII despite a complete lack of str

22 Classical T4 phage engineering and several newly proposed methods

23 selection is a major rate limiting factor in T4 phage engineering via CRISPR/Cas9.

24 th the putative DNA specificity motif of the T4 phage fork regression protein UvsW.

25 tory has reported data suggesting a role for T4 phage gene 32 single-stranded DNA-binding protein in

26 quilibrium (un)folding intermediate state of T4 phage gene product 45 (gp45, also known as DNA polyme

27 I-TevI, the T4 phage GIY-YIG intron endonuclease, functions both in

28 (highly antigenic outer capsid) protein for T4 phage hoc gene display were constructed by co-transfo

29 r burst size, however, the overall cost of a T4 phage infection is only 2-3% of the cost of an influe

30 oli NDP kinase is dispensable for successful T4 phage infection, and they deal with two observations

31 In T4 phage infection, lysis occurs when the holin protein

32 lar insights into the mechanistic pathway of T4 phage infection.

33 3, activates Lit during the latter stages of T4 phage infection.

34 ombination-dependent DNA replication late in T4 phage infection.

35 model simulating the diffusion due to mucin-T4 phage interactions was developed and calibrated to em

36 The enzyme is inhibited by the T4 phage internal protein I* (IPI*) to which it was foun

37 ivo conditions to the genomic composition of T4 phage is discussed.

38 Our results suggest that the mtDNA may use a T4 phage-like mechanism of replication and that the line

39 Subsequently, T4 phage markers were detected by liquid chromatography

40 herefore propose the mnemonic nudE.1 for the T4 phage orthologue.

41 ropose that the general advantage enjoyed by T4 phage, over almost all of its relatives, is a cumulat

42 In vivo the T4 phage packaging motor deals with Y- or X-structures i

43 , the physical presence of gp3 in the mature T4 phage particle and localized it to the tail tube.

44 We demonstrated that T4 phage particles displayed subdiffusive motion in mucu

45 cell is subjected to secondary infections by T4 phage particles.

46 T4 phage polynucleotide kinase (PNK) displays 5'-hydroxy

47 ts in the T4 replication system in vitro and T4 phage production in vivo.

48 Wild-type T4 phage production was not diminished by the polA12 mut

49 The T4 phage protein Arn (Anti restriction nuclease) was ide

50 tructural stability and ease of manufacture, T4 phage provides an excellent needle-free, mucosal pand

51 We further showed that T4 phage rapidly evolves to counter these novel defenses

52 Nevertheless, T4 phage reduced bacterial colonization of the epitheliu

53 ng strand synthesis during various stages of T4 phage replication.

54 ed that mutation rates, as determined by the T4 phage rI forward assay and rII reversion assay, were

55 s for intron mobility were determined in the T4 phage system using an in vivo assay to measure intron

56 edness opposite that of contracted sheath of T4 phage tail and is organized in an interlaced two-dime

57 The sheath is similar to that of the T4 phage tail but with a different arrangement of the su

58 ue sequence in the major head protein of the T4 phage (the Gol sequence) which then cleaves site-spec

59 rains of Escherichia coli K-12 infected with T4 phage this process is mediated by the host-encoded Li

60 mal protein expression and minimal impact on T4 phage titers.

61 We engineer T4 phage to express a serine protease inhibitor of a pro

62 Here, we experimentally evolved T4 phage to overcome a phage-defensive toxin-antitoxin s

63 of the CRISPR/Cas9 system, the genome of the T4 phage was modularly engineered to carry lacZ-alpha (l

64 Working with the virulent T4 phage, which targets resident, nonpathogenic Escheric

65 Our previous work demonstrated that T4 phage with Hoc proteins exposed on their capsid adher