ライフサイエンスコーパス: T4

1 nes containing the DNA vector (groups T3 and T4).

2 to promote and encourage early stimulation (T4).

3 triiodothyronine (T3) and higher thyroxine (T4).

4 ic health practice and policy interventions (T4).

5 m3 cells provide most synaptic contacts onto T4.

6 ies competition relative to incubations with T4.

7 l proteins of bacteriophages phi29, SPP1 and T4.

8 erent triangulation numbers in bacteriophage T4.

9 PBDEs is associated with a decrease in serum T4.

10 ss) DNA binding protein of the bacteriophage T4.

11 he TH receptor, whereas DIO3 degrades T3 and T4.

12 e seven found in the equivalent structure in T4.

13 id not change significantly from T0 to T2 or T4.

14 -mismatched portal vertex from bacteriophage T4.

15 t and TBARS value were observed in treatment T4.

16 >2.9 mm predicted greater OA advancement at T4.

17 in T3, a lower IgA/IgG ratio was observed in T4.

18 Physiologically relevant T3 (1 nM) and T4 (100 nM) concentrations in OVCAR-3 (high alphavbeta3)

19 ceptor, binds thyroid hormones (L-thyroxine, T4; 3,5,3'-triiodo-L-thyronine, T3) and is overexpressed

20 tion and PEf1 eliminated E. coli faster than T4 (36 vs 42 h).

21 : 50 mg of sodium nitrite and 0.150 uL/g TP; T4: 50 mg of sodium nitrite, 0.075 uL/g TP and 0.075 uL/

22 group had higher pathologic T stage (pT3 and T4: 86% v 73%; P < .01), higher positive lymph nodes (73

23 th a 2.6-mug/dL decrease in total thyroxine (T4) (95% CI: -4.7, -0.35).

24 mucus did not enhance the encounter rate of T4 against bacteria.

25 y not be optimal in some cases when based on T4 alone.

26 DNA-binding protein gp32 from bacteriophage T4 and a strand-displacing DNA polymerase.

27 representative DNA and RNA viruses, namely, T4 and influenza.

28 nt homologous recombination in bacteriophage T4 and is the functional analog of the eukaryotic Rad52

29 lytic tracer phages (Escherichia coli phage T4 and marine phage PSA-HS2) and two mycelia of differin

30 Both T4 and metformin alleviated contextual fear memory defic

31 We propose that neonatal administration of T4 and metformin post FAE affect memory via elevating Dn

32 The present results indicate that T4 and metformin, administered during the neonatal perio

33 umors were associated with higher Ca19.9, T3-T4 and N1, higher grade, perineural invasion, R1 resecti

34 It is well accepted that T4 and other phages have evolved counterdefense mechanis

35 he genomes of bacteriophages lambda, T5, T7, T4 and R1-37 and investigated the ability of these strai

36 subcellular fractions with thyroid hormones (T4 and rT3 separately) and measuring changes in thyroid

37 urvival rate and trunk diameter, followed by T4 and T2, indicating that Na and, to a lesser extent, C

38 Treatment groups T4 and T5 (n = 12 each) received three 10 or 30 mg/kg IV

39 Both T4 and T5 cells comprise four subtypes with directional

40 We found that all four subtypes of both T4 and T5 cells implement both mechanisms, that is prefe

41 In the fruit fly optic lobe, T4 and T5 cells represent the first direction-selective

42 ee of direction selectivity observed in both T4 and T5 cells within each subpopulation.

43 ionally selective small-field neurons called T4 and T5 form a spatial map in the lobula plate, where

44 In vivo calcium imaging revealed that T4 and T5 neurons encode the location and polarity of st

45 nectivity information for inputs to both the T4 and T5 pathways in a single EM dataset covering the e

46 when the elementary motion detector neurons T4 and T5 were silenced.

47 se correlations in Drosophila's EMD neurons, T4 and T5.

48 ive neurons, the elementary motion detectors T4 and T5.

49 imal MDTCS domains and a hinge point between T4 and T5.

50 two prototypical phages of Escherichia coli, T4 and T7, use small proteins to "puppeteer" the bacteri

51 ized in model systems provided by coliphages T4 and T7.

52 h quantifies the uptake of the bacteriophage T4 and the enteric virus echovirus 11 when exposed to th

53 NIS KO mice showed undetectable serum T4 and very low serum T3 levels when fed a diet supplyin

54 For patients at a high risk of recurrence (T4 and/or N2), adjuvant chemotherapy should be offered f

55 23.42%) and 2,491 (76.58%) patients with pT3/T4 and/or pN+ UTUC received AC and observation, respecti

56 ived AC versus observation after RNU for pT3/T4 and/or pN+ UTUC.

57 received AC or observation after RNU for pT3/T4 and/or pN+ UTUC.

58 mized to 4 treatment groups (T1, T2, T3, and T4) and received intramuscular injections at 0, 1, 3, an

59 hormones as in other vertebrates: thyroxin (T4) and triiodothyronine (T3), making the zebrafish a ve

60 hyroglobulin), which contain both thyroxine (T4) and triiodothyronine (T3), were the first pharmacolo

61 dium-chloride (T3), sodium-chloride/sulfate (T4), and calcium/magnesium-chloride/sulfate (T5).

62 gland secretes primarily tetraiodothyronine (T4), and some triiodothyronine (T3).

63 er tubes of contractile tail phages, such as T4, and its C-terminal domain adopt an Ig-like fold of u

64 viruses of Escherichia coli (phages T6, T2, T4, and T7).

65 al in patients with resectable high-risk T3, T4, and/or N2 CC on baseline computed tomography (CT) sc

66 y selective neuron in the ON motion pathway (T4) as well as its primary input neurons (Mi1, Tm3, Mi4,

67 500 in T1, 494 in T2, 499 in T3, and 500 in T4) at baseline who were assessed at 1-year and 2-year i

68 We show for the T4 bacteriophage DNA replication system that primer-prim

69 midine nucleotide biosynthetic pathway using T4 bacteriophage genes to achieve approximately 63% repl

70 a form of interdigital capacitor coated with T4 bacteriophage gp37 adhesin.

71 iates DNA replication forks at late times of T4 bacteriophage infection.

72 ding protein [gene product 32 (gp32)] of the T4 bacteriophage is a central integrating component of t

73 baseplate structures of the (DNA-containing) T4 bacteriophage(5).

74 The ~ 20% inhibition in FITC-T4 binding observed for the mixtures reflecting median c

75 re might decrease the binding of T4 to serum T4 binding proteins.

76 WT-TTR with small molecules that occupy the T4 binding site eliminated the inhibitory capacity of th

77 In addition, novel data indicated that T4, but not T3, controls integrin's outside-in signaling

78 ng orders of magnitude more progeny than the T4(C) mutant, which contains unmodified cytosines.

79 60-A-diameter isometric mutant bacteriophage T4 capsid has been determined.

80 hree tumors were Tis, 37 were T1, 19 were T2-T4 carcinomas, and 233 were benign lesions.

81 e had previously found that upward-sensitive T4 cells implement both preferred direction enhancement

82 In Drosophila, the T4 cells of the medulla are directionally selective and

83 the first direction-selective neurons, with T4 cells responding selectively to moving brightness inc

84 the circuits of Drosophila's motion-sensing T4 cells using a novel EM technique.

85 of the connections between these neurons and T4 cells using neuronal photoactivation.

86 the neuron types with the most synapses onto T4 cells.

87 o the T4S machinery is the membrane-embedded T4 coupling complex (T4CC).

88 selective and that selectivity arises in the T4 dendrites.

89 ria do not propagate coliphages and hindered T4 diffusion through the biofilm.

90 e identified which neurons are necessary for T4 directional selectivity and ON motion behavioral resp

91 tumor characteristics: 263 (80%) with T3 or T4 disease, 215 (66%) N1, and 62 (19%) with celiac nodal

92 t loss were significantly associated with T3/T4 disease.

93 For patients with locally advanced (T3, T4) disease, organ-preservation surgery, combined chemot

94 ng of two fluorescently labeled DNA with the T4 DNA ligase on the single-molecule level.

95 SplintR Ligase is 100X faster than either T4 DNA Ligase or T4 RNA Ligase 2 for RNA splinted DNA li

96 We show that the T4 DNA ligase repairs sticky ends more efficiently than

97 We describe the application of T4 DNA ligase-catalyzed DNA templated oligonucleotide po

98 The development and in-depth analysis of T4 DNA ligase-catalyzed DNA templated oligonucleotide po

99 ded by DNA exonucleases or ligated by T3 and T4 DNA ligases.

100 ) is needed to produce the long concatemeric T4 DNA molecules that serve as substrates for packaging

101 to interactions with other components of the T4 DNA replication complex are discussed.

102 p at the modification site that is sealed by T4-DNA ligase, yielding a product strand missing the mod

103 o an oral liquid formulation with the same L-T4 dosage, TSH circulating levels were normalized.

104 The excellent combination of T4 ductility (31%), T4 formability (7.8 mm) and T6 yield

105 e of 7.8 mm in a solution-treated condition (T4), due to its weak and split basal texture and fine gr

106 Tailed bacteriophage T4 employs one of the fastest and most powerful packagin

107 Previous work with the classic T4 endonuclease V digestion of DNA from irradiated Droso

108 Four homozygous transgenic lines (T4) expressing the mutant 1Ax1 gene (mut1Ax1) were produ

109 ruct by fusing a foldon domain (FD) of phage T4 fibritin to the MA C terminus.

110 ete with the thyroid hormone (TH) thyroxine (T4) for binding to transthyretin (TTR).

111 excellent combination of T4 ductility (31%), T4 formability (7.8 mm) and T6 yield strength (270 MPa)

112 Our recent study of T4 found that the integration of offset depolarizing and

113 The virus bacteriophage T4, from the family Myoviridae, employs an intriguing co

114 We found that the phage T4 genome modified by cytosine hydroxymethylation and gl

115 nation proteins encoded by the bacteriophage T4 genome, plus two homologous DNA molecules, we have re

116 mum tHb, oxyHb, and deoxyHb of Tis-T1 and T2-T4 groups were 89.3 mumol/L +/- 20.2 (standard deviation

117 commended for patients with thick melanomas (T4; > 4.0 mm in Breslow thickness), after a discussion o

118 The severe asthma clusters (T2, T3, and T4) had higher sputum eosinophilia than cluster T1, with

119 WT T4 has a prolate capsid characterized by triangulation n

120 PET/CT has high NPV for the N0 neck in T2 to T4 HNSCC.

121 During T4 homologous recombination, the UvsX recombinase has to

122 % confidence interval (CI), 1.17-3.51], ypT3-T4 (HR = 2.69; 95% CI, 1.19-6.08) and positive lymph nod

123 tical analyses, the emergent subdiffusion of T4 in mucus did not enhance the encounter rate of T4 aga

124 cy of polyvalent phage PEf1 versus coliphage T4 in suppressing a model enteric bacterium (E. coli K-1

125 In all patients who received L-T4 in tablet form after switching to an oral liquid form

126 e hypothyroid range) while in therapy with L-T4 in tablet.

127 ts who were switched back again to receive L-T4 in tablets, maintaining the dosage, TSH levels worsen

128 issues, capable of lowering serum thyroxine (T4) in rats.

129 A ribosome profiling analysis of phage T4-infected Escherichia coli yielded protected mRNA frag

130 gy budget during the infection reveal that a T4 infection consumes about a third of its host's energy

131 Bacteriophage T4 infects the bacterial host (Escherichia coli) using a

132 vanced invasive breast cancer (tumor size T3/T4), inflammatory breast cancer, or ductal carcinoma in

133 scribing the nonlinear dynamics of the phage T4 injection machinery interacting with a host cell.

134 ctions of the energetics and dynamics of the T4 injection machinery using a novel dynamic model.

135 he energetics, timescale, and pathway of the T4 injection process as well as the force available for

136 We uncover complex T4 inputs and reveal that putative excitatory inputs clu

137 enerated by E. coli's motility combined with T4 interacting with mucins may be the mechanism for incr

138 en (250 women in each of the T0, T1, T2, and T4 intervention groups and 248 in the T3 intervention gr

139 In the brain, T4 is converted to the active form T3 by type 2 deiodina

140 en, leads us to believe that absorption of L-T4 is greater with oral liquid formulations in these pat

141 Although the atomic structure of T4 is largely known, the dynamics of its fascinating inj

142 coli Although the atomic structure of phage T4 is largely understood, the dynamics of its injection

143 similar for patients classed as T4a and T4b, T4 is no longer subdivided in the re-termed ICON-S T cat

144 Cluster T4 is predominantly composed of obese female patients wi

145 teristics, with a lower proportion of T3 and T4 lesions (27.9% v 39.8%), fewer patients with positive

146 l (0.08 to 3.99 mU per liter) and a low free T4 level (<0.86 ng per deciliter).

147 usted to attain a normal thyrotropin or free T4 level (depending on the trial), with sham adjustments

148 more per liter and a normal free thyroxine (T4) level (0.86 to 1.90 ng per deciliter [11 to 24 pmol

149 ure to TTR-binding compounds and circulating T4 levels in humans has been reported, so far.

150 ain development appear very sensitive to low T4 levels, we maintain that PFHxS is of potential concer

151 and phosphate stress (psbA, psbD and pstS in T4-like and psbA in T7-like), but the proportion of cyan

152 in deep T7-like cyanophages, suggesting that T4-like and T7-like cyanophages have different host-deri

153 Myoviruses, bacteriophages with T4-like architecture, must contract their tails prior to

154 opical Pacific Ocean, composing up to 28% of T4-like cyanomyophages.

155 ist cyanophages belonging to the T7-like and T4-like cyanophage families.

156 Tracking relatives of published T4-like cyanophages and pelagiphages reveals high genomi

157 rast to the ETNP, in the oxic North Atlantic T4-like cyanophages encoded psbA and pstS throughout the

158 ctically all interactions against generalist T4-like cyanophages.

159 This cyanophage, P-TIM68, belongs to the T4-like myoviruses, has a prolate capsid, a long contrac

160 Network analysis including T4-like phage genotypic data revealed distinct viral var

161 , while only about 29% of the identified non-T4-like viruses and 30% of the contigs in the study pote

162 we estimate that about 95% of the identified T4-like viruses in viral tagging experiment infect Synec

163 e biosynthesis genes increased with depth in T4-like, but not T7-like cyanophages.

164 patients were switched to receive an oral L-T4 liquid formulation maintaining the same dosage.

165 % and 96%, respectively, for patients with < T4, < N2c, and </= 10 pack-year smoking history who were

166 luorescence spectroscopic toolkit to monitor T4 Lysozyme (T4L) in action by unraveling the kinetic an

167 Simulations of wild-type T4 lysozyme also reveal that benzene-egress-associated d

168 ir thermodynamics using the variant 118R1 of T4 lysozyme as an example.

169 nding of 1,2-azaborines to model cavities in T4 lysozyme in direct comparison to their carbonaceous c

170 e dissociation from the buried cavity of the T4 lysozyme Leu99Ala mutant (L99A).

171 e an 85% accuracy predicting outcomes of the T4 lysozyme mutation variants.

172 use them to predict effects of mutations in T4 lysozyme structures.

173 ere, we analyze the folding and unfolding of T4 lysozyme with optical tweezers under a chemo-mechanic

174 cture that interacts with the IR via MxiG(C) T4 lysozyme-mediated insertional mutagenesis of MxiK rev

175 stem determined using a fusion strategy with T4 lysozyme.

176 rotein model systems: barnase, spectrin, and T4 lysozyme.

177 nergy landscape of the L99A cavity mutant of T4 lysozyme.

178 L-thyroxine (L-T4) malabsorption is a potential concern in patients wit

179 The T4 metabolite TETRAC was the most active TH on PPARgamma

180 ted by substrate DNA sequence: (i) the phage T4 motor exhibits large translocation rate fluctuations

181 synthetic A-philic, GC rich sequences by the T4 motor.

182 The analysis of the T4 mutant head assembly gives guidance to how other icos

183 Instead, for static E. coli, the diffusive T4 mutant lacking Ig domains outperformed the subdiffusi

184 before and after 6 weeks of treatment with L-T4 (n=15) or placebo (n=10) in 12 volumes of interest (V

185 s were stratified by T category (T1-T2 vs T3-T4), N category (N0-N2a vs N2b-N3), Zubrod performance s

186 In total, 344 patients with T1-T4, N0-N2 breast cancer (352 lesions) were included.

187 n clinical categories T1-T2, N2a-N3 M0 or T3-T4, N0-N3 M0; Zubrod performance status 0 or 1; age at l

188 utional trial wherein women with clinical T0-T4,N1-N2,M0 breast cancer underwent SLN surgery and axil

189 with a telescope while recording from single T4 neurons, we find both mechanisms at work implemented

190 The kinetics of T4 O and IRD were also investigated, although a definiti

191 T4 (ON) and T5 (OFF) are the first neurons in their resp

192 f six marine phages and two coliphages (MS2, T4) on transport in sand-filled percolated columns.

193 asing T Stage (T3 OR 3.36, 95% CI 2.52-4.50, T4 OR 6.30, 95% CI 4.71-8.42), and tumor grade (G3 OR 5.

194 tage II (T1-T2N2 or T3N0-N2), and stage III (T4 or N3).

195 sory percept by selectively silencing either T4 or T5 neurons.

196 Patients with cT3/T4 or Tx N+ tumors of the mid or lower rectum who had re

197 Patients with cT3/T4 or TxN+ tumors of the mid or lower rectum who had rec

198 We administered vehicle, thyroxine (T4) or metformin to neonatal rats post FAE and rats were

199 ted either active treatment (T1, T2, T3, and T4) or placebo (C1, C2, C3, and C4).

200 iated with total triiodothyronine (T3), free T4, or thyroid-stimulating hormone (TSH).

201 These results suggest that the L-T4 oral liquid formulation could circumvent the pH alter

202 T) T3 and TT4, thyroid histology and hepatic T4-ORD were determined at the final 18 day exposure.

203 was no effect on plasma FT3, TT3, or hepatic T4-ORD.

204 T4 (P < 0.0001) and node-positive tumors (P < 0.0001) we

205 0 (8.5-19.4) at T2 and to 12.5 (8.2-15.9) at T4 (P < 0.001).

206 gglutinin skin test, p < 0.0001), thyroxine (T4, p = 0.042), and glutathione (GSH, p = 0.034) concent

207 ssfully corroborate previous findings in the T4 pathway and comprehensively identify inputs and recep

208 Interestingly, the costs of building a T4 phage and a single influenza virus are nearly the sam

209 r increasing the encounter rates between the T4 phage and E. coli bacteria.

210 Classical T4 phage engineering and several newly proposed methods

211 selection is a major rate limiting factor in T4 phage engineering via CRISPR/Cas9.

212 quilibrium (un)folding intermediate state of T4 phage gene product 45 (gp45, also known as DNA polyme

213 r burst size, however, the overall cost of a T4 phage infection is only 2-3% of the cost of an influe

214 In T4 phage infection, lysis occurs when the holin protein

215 model simulating the diffusion due to mucin-T4 phage interactions was developed and calibrated to em

216 rces for the interaction between hydrophobic T4 phages and hydrophobic C. cinerea surfaces.

217 icantly improves the genomic editing rate of T4 phages.

218 In several phages and viruses, including T4, Phi29, and herpes simplex virus 1 (HSV-1), the porta

219 Unlike T4 pilins, where E5 residue substitutions also abolish N

220 fter nephroureterectomy staged as either pT2-T4 pN0-N3 M0 or pTany N1-3 M0.

221 luorescence assay for sensitive detection of T4 PNK activity has been developed by multifunctional ma

222 nd accomplished exceptional characterization T4 PNK activity in cell extracts, offering a powerful to

223 Sensitive detection of T4 PNK activity is critical to both clinical diagnosis a

224 The aberrant activity of T4 PNK has been proven to be associated with a variety o

225 esign, the HP-MBs here serve together as the T4 PNK, DNA polymerase, and endonuclease recognition pro

226 Then, in the presence of T4 PNK, the 3'-phosphoryl of HP-MBs was hydrolyzed to 3'

227 riant show that it docks better into the TTR T4 pocket than tafamidis, so far the only drug on the ma

228 T4 polynucleotide kinase (PNK) plays critical roles in r

229 o-RNA-seq") incorporating RNA treatment with T4-polynucleotide kinase, which we compared with standar

230 h that of single subunits of Phi29, SPP1 and T4 portal proteins revealed remarkable similarity.

231 pete for TTR-binding with a fluorescent FITC-T4 probe.

232 Thyroidal T4 production results from iodination of thyroglobulin (

233 rects sigma, and therefore RNAP activity, to T4 promoter DNA, and demonstrate at a molecular level ho

234 The five T4 proteins that catalyze DNA synthesis on the leading s

235 At the community and population level (T4), public awareness campaigns need thorough impact ass

236 ith protein coadministered at M3 and M6; and T4 received protein and DNA coadministered at each vacci

237 the optic lobe, particularly in ON-pathway (T4) receptive-field circuits, in concert with physiologi

238 influence on the oncological outcomes of T3/T4 rectal cancers.

239 perchlorate and decreasing total thyroxine (T4) [regression coefficient (beta) = -0.70; 95% CI: -1.0

240 roportions with combined tumour stage T3 and T4 remained constant.

241 The T4 replisome has provided a unique opportunity to invest

242 (O and IRD) of T3 and 3,3'-T2 formation from T4, respectively, with an estimated IC50 of 160 nM; no s

243 sponses had higher response rates for T3 and T4, respectively.

244 Neonatal T4 restored maternal allelic expressions of the imprinte

245 is identified tumor-characteristics (primary T4, right colon), biological features (K/N-RAS status),

246 bers of the ATP-dependent RNA ligase family (T4 RNA ligase 1; Rnl1) and the NAD(+)-dependent DNA liga

247 is 100X faster than either T4 DNA Ligase or T4 RNA Ligase 2 for RNA splinted DNA ligation.

248 LISH utilizes the T4 RNA Ligase 2 to efficiently join adjacent chimeric RN

249 on of Y-shaped adapter to mature tRNAs using T4 RNA Ligase 2.

250 SPR-Cas system through proximity ligation by T4 RNA ligase and find 34 sRNAs linking to CRISPR loci.

251 ase-paired targets in bacteria co-expressing T4 RNA ligase, followed by sequencing to identify the ch

252 l that putative excitatory inputs cluster at T4's dendrite shafts, while inhibitory inputs localize t

253 ociated with the risk of muscle-invasive (T2-T4 stage) compared with non-muscle-invasive (Ta, T1 stag

254 node-positive disease, or locally invasive (T4 stage) prostate cancer, those with previous or synchr

255 n fast progress (i.e. 14 months from T1 to a T4 stage), nonspecific symptoms with delay in diagnosis,

256 Pathologic T3b/T4 stage, Gleason score 8-10, lymph node invasion, and D

257 The GalNAc-T4 structure bound to a monoglycopeptide shows that the

258 ons, either through inhibition of thyroxine (T4) synthesis or through inhibition of Dio mediated conv

259 y) and measuring changes in thyroid hormone (T4, T3, rT3, and 3,3'-T2) concentrations.

260 Eight subtypes of T4/T5 neurons are defined by combinations of two pattern

261 e ion channels para and Ih in motion-sensing T4/T5 neurons of the Drosophila visual system.

262 Here, we focused on Drosophila T4/T5 neurons, a class of closely related neuronal subty

263 4 vertebrates shows the long propeptide, T3, T4, T6, and T6a domains have been deleted several times

264 mutations of basic residues that line phage T4 TerS (gp16) channel do not disrupt DNA binding.

265 Here we report studies on GalNAc-T4 that reveal the origins of its unique N-terminal long

266 the kestrels increased elimination of plasma T4 through Phase II enzymes.

267 PBDE exposure might decrease the binding of T4 to serum T4 binding proteins.

268 The accelerated conversion of T4 to T3 within myocytes mediates part of the PGC-1a ind

269 ugh inhibition of Dio mediated conversion of T4 to T3.

270 area regions at the C2 to C3, C4 to C5, and T4 to T9 levels.

271 ) T-cell frequency (p = 0.04) correlate with T4 to T9 spinal cord cross-sectional area in HAM/TSP.

272 ant increase of yield strength from 159 MPa (T4) to 270 MPa (T6).

273 lves the endogenous conversion of thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and may not be optim

274 sm was generated by addition of L-thyroxine (T4) to drinking water.

275 g supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows p

276 DIO2 converts thyroxine (T4) to triiodothyronine (T3), which binds to the TH rece

277 passing of a 50-nt non-coding gap in a phage T4 topoisomerase subunit gene (gp60) requires several re

278 Adjunctive L-T4 treatment produced a significant decline in depressio

279 In a previous pilot study, L-T4 treatment reduced depression scores and activity with

280 i) was used to estimate inhibition levels of T4-TTR binding in human blood.

281 serum was extrapolated to 1.3% inhibition of T4-TTR binding in maternal and 1.5% in infant blood.

282 ding potency to in vivo inhibition levels of T4-TTR binding in maternal and infant serum.

283 acement from TTR in vitro relates to in vivo T4-TTR binding is unknown.

284 ypothesize, however, that 1.3% inhibition of T4-TTR binding may ultimately be decisive for reaching a

285 Dose escalation in T3-T4 tumors did not increase local control.

286 Patients with T3-T4 tumors underwent a second random assignment 1:1 betwe

287 served in 95%-100% of participants in T3 and T4, two weeks after final vaccination at high magnitude.

288 ollowed by a 1-wk washout period, then 4 wk (T4) using the alternate OA.

289 rotein (gp59) and a Rad51/RecA analogue (the T4 UvsX strand-exchange protein).

290 0.37), P < 0.001] and more advanced T-stage [T4 vs T0-T2, OR 0.28 (0.23-0.34), P < 0.001] and M-stage

291 Although T4 was more effective than PEf1 in infecting E. coli K-1

292 T4 was slightly more effective in suppressing E. coli in

293 s of NYVAC vector and gp120 Env protein; and T4 was two doses of DNA vector and gp120 Env protein fol

294 stration of gp120 Env protein (groups T2 and T4) was associated with a substantially earlier and high

295 d de novo independently of deiodination from T4 We found that upon iodination in vitro, de novo T3 fo

296 In patients treated with L-T4, we found a significant decrease in regional activity

297 Building on our estimates for T4, we show how the energetic costs of double-stranded D

298 the median differences between T0 and T2 and T4 were highly significant (P < 0.001).

299 Plasma free (F) T3 and T4 were measured at baseline, and at 9 days and 18 days

300 ing Ig domains outperformed the subdiffusive T4 wild type.