ライフサイエンスコーパス: TMP

1 TMP provided valuable diagnostic information by unmaskin

2 TMP reached maximal levels on day 3 after drug administr

3 TMP residues were measured above LOD (0.3 mug kg(-)(1))

4 TMP-AcBOPDIPY rapidly labeled engineered eDHFR tags via

5 TMP-SMX administration significantly reduced liver stage

6 TMP-SMX inhibited development of rodent and P. falciparu

7 TMP-SMX is not gametocytocidal, but at prophylactic leve

8 TMP-SMZ may be used safely for prophylaxis of recurrent

9 TMP-SMZ may be used safely for prophylaxis of recurrent

10 ubjects were randomly assigned to group 1 (1 TMP-SMZ dose every other day for 311 days) or group 2 (1

11 unteers were randomly assigned to Group 1 (1 TMP-SMZ tablet every 2 days for 311 days) or Group 2 (1

12 gated and compared to previously reported (1-TMP-2-BH2-C6H4)2 (1; TMP = tetramethylpiperidyl) and (1-

13 previously reported (1-TMP-2-BH2-C6H4)2 (1; TMP = tetramethylpiperidyl) and (1-NMe2-2-BH2-C6H4)2 (4;

14 We report that (TMP)Ru(NH(3))(2) (TMP = tetramesitylporphryin) is a molecular catalyst for

15 m alkylmagnesium amide [Na4Mg2(TMP)6(nBu)2] (TMP=2,2,6,6-tetramethylpiperidide), a template base as i

16 olones (35%), followed by carbapenems (20%), TMP-SMX (18.5%), and ceftazidime (11%).

17 mploying [5',5"-D,D]-5'-dThd, [5',5"-D,D]-5'-TMP, [CD(3)]-dThd and [CD(3),6D]-dThd, we find unequivoc

18 nM, respectively) when assayed with p-Nph-5'-TMP as a substrate.

19 ophenyl 5'-thymidine monophosphate (p-Nph-5'-TMP) as an artificial substrate.

20 confirmed by employing (15)N substituted 5'-TMP.

21 up 9 hydrazido(2-) complex, Cp*IrN(TMP) (6) (TMP=2,2,6,6-tetramethylpiperidine) is reported.

22 ) clindamycin-treated and 182 of 198 (91.9%) TMP-SMX-treated subjects (difference, 0.2%; 95% confiden

23 g E. hirae harboring this prophage mounted a TMP-specific H-2K(b)-restricted CD8(+) T lymphocyte resp

24 occal prophage in stools and expression of a TMP-cross-reactive antigen by tumors correlated with lon

25 ICLs generated by trioxsalen/ultraviolet A (TMP/UVA) during development and aging.

26 with A-TMP-fluorescein, A-TMP-Dapoxyl, and A-TMP-Atto655.

27 ar protein targets with A-TMP-fluorescein, A-TMP-Dapoxyl, and A-TMP-Atto655.

28 ed an acrylamide-trimethoprim-fluorophore (A-TMP-fluorophore v2.0) electrophile with an optimized lin

29 sis for routine production of a variety of A-TMP-probe v2.0 labels.

30 ct the covalent trimethoprim chemical tag (A-TMP-tag) has on the SM imaging performance of the fluoro

31 cell environment and demonstrate that the A-TMP-tag complements the advantageous SM imaging properti

32 es for SM imaging and demonstrate that the A-TMP-tag with Atto655 and Alexa647 are promising reagents

33 properties of these fluorophores and their A-TMP-tag conjugates.

34 aving an 8-min half-life for reaction with A-TMP-biotin v2.0 in vitro.

35 g of various cellular protein targets with A-TMP-fluorescein, A-TMP-Dapoxyl, and A-TMP-Atto655.

36 e was 39% against ciprofloxacin, 44% against TMP-SMX, and 25% against cefuroxime.

37 anometallic reagents (Mg(CH2 SiMe3 )2 and Al(TMP)iBu2 ), key intermediates in this process have been

38 y or pharmacologically, partially alleviates TMP-mediated inhibition of CTL activity, suggesting that

39 solate, and 5% were resistant to ampicillin, TMP-SMX, and chloramphenicol.

40 line (n = 2351), sulfadiazine (n = 870), and TMP-SMX (n = 23 602).

41 Mixing of KOtBu, BuLi, and TMP(H) in heptane gave a solution of the base mixture wh

42 ngs where MRSA is prevalent, clindamycin and TMP-SMX produce similar cure and adverse event rates amo

43 gnificant difference between clindamycin and TMP-SMX, with respect to either efficacy or side-effect

44 kis(pentafluorophenyl)porphyrin dianion) and TMP (tetramesitylporphyrin dianion), with and without im

45 iocakes, indicating that membrane fluxes and TMP evolution levels had significant effects on the abun

46 encoded chemical tags CLIP, SNAP, Halo, and TMP for tissue labeling; this resulted in >100-fold incr

47 Susceptibilities to levofloxacin and TMP-SMZ were 29.3% and 36.6%, respectively.

48 We characterized NNRTI and TMP-SMX effects on Plasmodium liver stages in vivo using

49 -effects and poor adherence by patients, and TMP-SMX alone is recommended in Australia.

50 Significant differences in the SMM and TMP concentrations between yolk and white in post treatm

51 Prenatal exposure to streptomycin and TMP-SMX was associated with select birth defects in some

52 ase inhibitor nevirapine, and the antibiotic TMP-SMX were assessed for activity against Plasmodium fa

53 f the iodonium moiety and unsymmetrical aryl(TMP)iodonium salts are primarily employed.

54 lts, we conducted in vitro studies assessing TMP-SMX effects on the rodent parasites P. yoelii and Pl

55 alations with sterically hindered TMP bases (TMP = 2,2,6,6-tetramethylpiperide) of magnesium and zinc

56 n of substituted toluenes using BuLi/KO-t-Bu/TMP(H) (LiNK metalation conditions) with subsequent in s

57 ction of feed constituents was influenced by TMP and RSF.

58 f ear drop prescriptions was used to compare TMP risk between quinolone and neomycin-exposed patients

59 th intact tympanic membranes should consider TMP risk.

60 robustness, this second-generation covalent TMP-tag adds to the limited number of chemical tags that

61 here we report a second-generation covalent TMP-tag that has a fast labeling half-life and can readi

62 xposed Ugandan WLHIV receiving ART and daily TMP/SXT to examine changes in inflammatory markers acros

63 ed, placebo-controlled trial comparing daily TMP-SMX plus monthly dihydroartemisinin-piperaquine (DP)

64 Our results indicate that despite daily TMP/SXT, MiP in WLHIV induced a systemic inflammatory re

65 the daily TMP-SMX plus DP arm and the daily TMP-SMX alone arm (6.1% vs. 3.1%; relative risk, 1.96; 9

66 acental malarial infection between the daily TMP-SMX plus DP arm and the daily TMP-SMX alone arm (6.1

67 dihydroartemisinin-piperaquine (DP) to daily TMP-SMX alone in HIV-infected pregnant women in an area

68 g of insecticide, adding monthly DP to daily TMP-SMX did not reduce the risk of placental or maternal

69 usly unreported increased risk of developing TMPs.

70 erformance exceeds almost all the documented TMP-based and non-noble-metal-based electrocatalysts.

71 peated exposures to malaria parasites during TMP-SMX administration induces stage-specific and long-l

72 richia coli dihydrofolate reductase (eDHFR), TMP-decorated iron oxide nanoparticles bind to eDHFR wit

73 ormation of the binary complexes with either TMP or NADPH and that the binary structures are approach

74 Emerging CC1292 expressed TMP-SMX resistance and decreased susceptibility to penic

75 lytic ORR by iron(tetramesitylporphyrin) (Fe(TMP)) in DMF.

76 R(TMP) on [O(2)] provided rate constants for TMP reaction, O(2) quenching, and lifetimes compatible w

77 s own mRNA depending on cellular demands for TMP.

78 r labile solid phase pools were observed for TMP than for SAs.

79 drops was associated with increased risk for TMP compared with neomycin plus hydrocortisone, with an

80 By inheriting the non-flammability from TMP and the high ion-transport kinetics from the carbona

81 ating that synthesis of [(3)H]TTP from [(3)H]TMP arose solely from the dephosphorysynthase pathway th

82 d the metabolism of [(3)H]thymidine or [(3)H]TMP as precursors of [(3)H]TTP in isolated intact or bro

83 The equivalent addition of [(3)H]TMP produced far less [(3)H]TTP than the amount observed

84 des deoxyuridine triphosphatelation of [(3)H]TMP to [(3)H]thymidine.

85 t TK2, the synthesis of [(3)H]TTP from [(3)H]TMP was effectively blocked, demonstrating that synthesi

86 3)H]thymidine was readily converted to [(3)H]TMP, but further phosphorylation was prevented even thou

87 on of long-lived CD62L(hi)Bcl-2(hi)Eomes(hi) TMPs.

88 However, the biocake (S2 and S4) at a high TMP level (i.e., after the TMP jump) had many more prote

89 irected metalations with sterically hindered TMP bases (TMP = 2,2,6,6-tetramethylpiperide) of magnesi

90 duces clinical episodes of malaria; however, TMP-SMX effect on Plasmodium liver stages requires furth

91 This work suggests that hybrid TMPs constitute an interesting class of materials for fu

92 ion of the hydroperoxo intermediate, Fe(III)(TMP)(OOH), to produce water versus dissociation of the H

93 To determine the role of the membrane in TMP metabolism, mitochondrial membranes were disrupted b

94 with three FO membranes and with increasing TMP up to a maximum of 50 psi (3.45 bar).

95 anes might slightly increase with increasing TMP, and RSF substantially declines with increasing TMP.

96 d RSF substantially declines with increasing TMP.

97 rminal Group 9 hydrazido(2-) complex, Cp*IrN(TMP) (6) (TMP=2,2,6,6-tetramethylpiperidine) is reported

98 rt and 0 degrees C using a mixed-metal Li/K-TMP amide comprised of KOtBu, BuLi, and 2,2,6,6,-tetrame

99 , which was induced by trimethoprim-lactate (TMP-lactate), which results in the death of intracellula

100 Resistance to at least TMP-SMX and ampicillin was present in 25% of isolate, an

101 y 3 isolates were resistant to levofloxacin, TMP-SMZ, and minocycline.

102 e prefers TMP synthesized by TK2 over medium TMP and that this is disrupted in broken mitochondria.

103 latory role of tumor-derived microparticles (TMPs)-extracellular vesicles shed from tumor cells-follo

104 t phosphorylation of thiamine monophosphate (TMP) to thiamine pyrophosphate.

105 rein the sodium alkylmagnesium amide [Na4Mg2(TMP)6(nBu)2] (TMP=2,2,6,6-tetramethylpiperidide), a temp

106 teria grayi We found that the acquisition of TMP resistance via decreased drug affinity is limited by

107 s to a postulate for the structural basis of TMP resistance in DHFR and also suggests design strategi

108 fusive, most likely caused by confinement of TMP mobility by the submembranous MreB network.

109 FR, the biocompatibility of the conjugate of TMP-iron oxide nanoparticles renders a convenient and ve

110 osensitized transformation rate constants of TMP decreased with increasing DOM preoxidation and were

111 inical rationale for clinical development of TMP in WM alone or in combination with inhibitors of MYD

112 All subjects were treated with 1 dose of TMP-SMZ (160 mg/800 mg) twice daily for 45 days, and all

113 aimed at determining the optimum duration of TMP-SMX prophylaxis in HIV-infected or HIV-exposed child

114 potential anti-infection immunity effect of TMP-SMX prophylaxis.

115 We compared the efficacy and side-effects of TMP-SMX with TMP-SMX plus doxycycline for the oral phase

116 are commonly prescribed, but the efficacy of TMP-SMX has been questioned.

117 mples after accounting for the inhibition of TMP photodegradation by DOM.

118 ween peak current intensity and logarithm of TMP concentration between 1.0 x 10(-6) and 1.0 x 10(-4)M

119 iously noted for the photosensitized loss of TMP, the incomplete inhibition of the enhanced RH2O2 fol

120 ly controllable factors in tuning the pKa of TMP-embedded charged residues is important for bioengine

121 and 4a as catalysts gave in the presence of TMP TOFs of up to 7.5 h(-1), producing [TMPH][formate] (

122 embrane fouling both in terms of the rate of TMP development and the properties of the membrane cake

123 bserved, we recommend the 12-week regimen of TMP-SMX for oral eradication treatment of melioidosis.

124 2.1.1.45), which catalyzes the synthesis of TMP and is the sole de novo source of TTP for DNA replic

125 All volunteers were treated with 1 tablet of TMP-SMZ (160 mg/800 mg) twice daily for 45 days, and all

126 A randomized controlled trial of TMP-SMZ prophylaxis in patients receiving biologics is n

127 The combined use of TMP with Bruton's tyrosine kinase or interleukin-1 recep

128 esistance to ceftazidime, and limited use of TMP-SMX.

129 Finally, we investigated how accumulation of TMPs affects diffusion of TMPs and IMPs of both the inne

130 nd outer leaflets by changing the density of TMPs.

131 ow accumulation of TMPs affects diffusion of TMPs and IMPs of both the inner and outer leaflets by ch

132 sociated, spectrin modifies the diffusion of TMPs and IMPs of the inner leaflet from normal to confin

133 s as a fence that restricts the diffusion of TMPs and IMPs of the inner leaflet within the membrane s

134 laments could modify transverse diffusion of TMPs and IMPs of the inner leaflet, depending on the str

135 in rings limit the longitudinal diffusion of TMPs and the IMPs of the inner leaflet but not of the IM

136 gesting that the immunomodulatory effects of TMPs in response to radiotherapy is mediated, in part, b

137 R signaling actively blocks the formation of TMPs responding to weak TCR agonists, thereby promoting

138 B cytoskeleton and regulates the mobility of TMPs.

139 ction is made for the reactivity and KIE of (TMP)Fe(IV) horizontal lineO complex, and a comparison is

140 acts H atoms from a bound ammonia ligand of (TMP)Ru(NH(3))(2), leading to the discovery of a new cata

141 ering and biomedical applications relying on TMP systems, in which the onset of functions can be cont

142 d LRV remained stable at different operating TMPs.

143 olates nonsusceptible to levofloxacin and/or TMP-SMZ.

144 incision and drainage alone, clindamycin or TMP-SMX in conjunction with incision and drainage improv

145 ved oral clindamycin 300 mg 4 times daily or TMP-SMX 320 mg/1600 mg twice daily, each for 7 days.

146 patients to receive TMP-SMX plus placebo or TMP-SMX plus doxycycline for 20 weeks (1:1; block size o

147 Twelve weeks of oral TMP-SMX is recommended in Australia, and 20 weeks in Tha

148 Recently, we successfully rendered our TMP-tag covalent with a proximity-induced reaction betwe

149 Tympanic membrane perforation (TMP) was identified as 2 inpatient or outpatient encount

150 ctron-donating solvent, trimethyl phosphate (TMP), the oxidation-vulnerable anion-carbonate affinitie

151 g an intrinsically safe trimethyl phosphate (TMP)-based electrolyte to build a stable Zn anode.

152 osed of layered transition metal phosphates (TMPs) covalently bound to organic absorber molecules to

153 alysts based on transition metal phosphides (TMPs) with cationic/anionic doping have been widely stud

154 muM inhibited (66-99%) the hydrolysis of pnp-TMP by both recombinant NPP1 and cell surface NPP1 activ

155 etical and stoichiometric methane potential (TMP, and SMP) were also estimated.

156 es for studying the transmembrane potential (TMP) induced during the treatment of biological cells wi

157 a small number of memory T cell precursors (TMPs) survive to form a pool of long-lived memory T cell

158 The preelectroporation TMP induced in tightly packed cells is analyzed for two

159 compartmentalized so that TMP kinase prefers TMP synthesized by TK2 over medium TMP and that this is

160 Among children prescribed TMP-SMX prophylaxis, there were no significant differenc

161 Among children not prescribed TMP-SMX prophylaxis, 4443 treatments for malaria were gi

162 The trans-membrane pressure (TMP) increase was similar in the early stages of the mem

163 iocake (S3) at a low transmembrane pressure (TMP) level (i.e., before the TMP jump) had larger gray i

164 rated that hydraulic transmembrane pressure (TMP), common in industrial operation of FO membrane elem

165 ncreasing operating transmembrane pressures (TMPs).

166 pes in the tail length tape measure protein (TMP) of a prophage found in the genome of the bacterioph

167 and membrane affects trans-membrane protein (TMP) diffusion and reveal that the mobility of the TMPs

168 charged residues in transmembrane proteins (TMPs) can control the onset of protein function.

169 hospholipid bilayer, transmembrane proteins (TMPs), and integral monotopic proteins (IMPs) in both th

170 ce the use of targeted multiplex proteomics (TMP) as a tool to simultaneously measure a panel of 54 p

171 y labeling proteins with trimethyl pyrylium (TMP), which forms a stable, positively charged label at

172 sensor was successfully applied to quantify TMP in urine samples.

173 strong acceptor tetracyano-p-quinodimethane (TMP/HMP-TCNQ) were grown by vapor diffusion.

174 R(TMP) was inversely proportional to dioxygen concentratio

175 rate of 2,4,6-trimethylphenol (TMP) loss (R(TMP)) on dioxygen concentration was examined both for a

176 tion, as well as the inverse dependence of R(TMP) on [O(2)] for these samples, suggests that there re

177 Modeling the dependence of R(TMP) on [O(2)] provided rate constants for TMP reaction,

178 We show that DD-Cre triggers rapid TMP-dependent recombination of loxP-flanked ('floxed') a

179 ce, we randomly assigned patients to receive TMP-SMX plus placebo or TMP-SMX plus doxycycline for 20

180 One participant who received TMP-SMX had a hypersensitivity reaction.

181 ria after DP treatment in children receiving TMP-SMX prophylaxis.

182 However, for children receiving TMP-SMX, associations were strong and evident for all sa

183 In children not receiving TMP-SMX, low piperaquine concentrations were only modest

184 Borohydride reduction significantly reduced TMP loss, supporting the role of aromatic ketone triplet

185 MOM group replaced TMP C ring and generated a potent analogue 15, which sho

186 The soils could resupply TMP so rapidly that in one soil, where Tc = 2 min, suppl

187 rim-sulfamethoxazole (TMP-SMX) and rifampin, TMP-SMX alone, rifampin alone, or tetracycline alone.

188 the isolated Ru(T-pMe-PP)((t)BuSH)(2) and Ru(TMP)(MeSSMe)(2), were characterized in situ.

189 mation of the bis(disulfide) complex from Ru(TMP)(MeCN)(2) in solution occurs with a cooperativity ef

190 disulfide in the solid state structure of Ru(TMP)(MeSSMe)(2) is eta(1)(end-on) coordinated, the first

191 quaternary substituted products (see scheme; TMP = 2,2,6,6-tetramethylpiperidine).

192 st carcinoma cells exposed to radiation shed TMPs containing elevated levels of immune-modulating pro

193 red during and after administration of a SMM/TMP combination in laying hens in doses of 8 g l(-)(1) a

194 ulfamethoxazole-trimethoprim 800/160 mg (SMZ/TMP) daily for 30 days followed by Monday, Wednesday, Fr

195 c gram-negative antibiotic resistance to SMZ/TMP (75% vs. 80%; P=1.00) and ciprofloxacin (16.7% vs. 3

196 an additional 5 months (Group 1) versus SMZ/TMP Monday, Wednesday, Friday for 6 months plus ciproflo

197 ntial sequestration of anions into solvating TMP domains around the metal cations.

198 d 1H-perfluoroalkane reagents, DMPU solvent, TMP(2)Zn base, and a copper chloride/phenanthroline cata

199 The compatibility of the strong TMP-bases with BF3.OEt2 (formation of frustrated Lewis p

200 aumanii in complex with a pair of substrates TMP and a non-hydrolyzable adenosine triphosphate analog

201 l evidence is trimethoprim-sulfamethoxaxole (TMP-SMX) plus doxycycline.

202 omycin (23%), trimethoprim-sulfamethoxazole (TMP-SMX) (9%), and cefuroxime (7%).

203 Trimethoprim-sulfamethoxazole (TMP-SMX) and fluoroquinolones were active against 94% an

204 Daily trimethoprim-sulfamethoxazole (TMP-SMX) and insecticide-treated nets remain the main in

205 included oral trimethoprim-sulfamethoxazole (TMP-SMX) and rifampin, TMP-SMX alone, rifampin alone, or

206 indamycin and trimethoprim-sulfamethoxazole (TMP-SMX) are commonly prescribed, but the efficacy of TM

207 lindamycin or trimethoprim-sulfamethoxazole (TMP-SMX) for 10 days.

208 lowed by oral trimethoprim-sulfamethoxazole (TMP-SMX) for 12 to 20 weeks.

209 ors (PIs) and trimethoprim-sulfamethoxazole (TMP-SMX) have known activity against parasites during li

210 Trimethoprim-sulfamethoxazole (TMP-SMX) is widely used in malaria-endemic areas in huma

211 nd prescribed trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis.

212 ose receiving trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis.

213 402 (36%) to trimethoprim-sulfamethoxazole (TMP-SMX), 355 (32%) to sulfamethoxazole-sulfisoxazole, 3

214 usceptible to trimethoprim-sulfamethoxazole (TMP-SMX), and all isolates were clindamycin susceptible.

215 clindamycin, trimethoprim-sulfamethoxazole (TMP-SMX), or placebo for 10 days.

216 Additionally, trimethoprim-sulfamethoxazole (TMP-SMX), used for opportunistic infection prophylaxis i

217 Trimethoprim-sulfamethoxazole (TMP-SMZ) and the fluoroquinolones have traditionally bee

218 usceptible to trimethoprim-sulfamethoxazole (TMP-SMZ), and this therefore represents a potentially at

219 RT) and daily trimethoprim-sulfamethoxazole (TMP/SXT).

220 adiazine, and trimethoprim-sulfamethoxazole [TMP-SMX]) and abstracted data on maternal, pregnancy, an

221 h as Bactrim (trimethoprim-sulfamethoxazole; TMP-SMX) continue to play an important role in treating

222 terruption, and 5 patients were still taking TMP-SMX.

223 of a small molecule inhibitor, terameprocol (TMP), targeting Sp1 activity in WM.

224 = the dianion of meso-tetramesitylporphyrin (TMP) or meso-tetrakis(4-methylphenyl)porphyrin (H(2)T-pM

225 u, BuLi, and 2,2,6,6,-tetramethylpiperidine (TMP(H)).

226 hindered base 2,2,6,6-tetramethylpiperidine (TMP) furnished H2 ligand deprotonation.

227 2,2,6,6-Tetramethylpiperidine (TMP)-catalyzed (1-10%) chlorinations of phenols by SO2Cl

228 chloride and 2,2,6,6-tetramethylpiperidine (TMP).

229 The COD(th), TMP, SMP values indicated IONPs efficacy for improving b

230 gainst these mutant enzymes and strains than TMP.

231 This work demonstrates that TMP is an effective probe for the determination of Rf,T

232 Despite the known effects that TMP-SMX has in reducing clinical malaria, its impact on

233 We next investigated and observed that TMP treatment induced further inhibition of WM cells in

234 Results revealed that TMP minimally affected water flux, reverse salt flux (RS

235 Our data show that TMP constitutes a promising, novel molecular prescreenin

236 nt malaria models, we previously showed that TMP-SMX, at prophylactic doses, can arrest liver stage d

237 salvage pathway is compartmentalized so that TMP kinase prefers TMP synthesized by TK2 over medium TM

238 ent of malaria parasites and speculated that TMP-SMX prophylaxis during repeated malaria exposures wo

239 Our findings suggest that TMP-SMX is not inferior to TMP-SMX plus doxycycline for

240 We report that (TMP)Ru(NH(3))(2) (TMP = tetramesitylporphryin) is a mole

241 The TMP-injected Tlr9(-/-) mice, and not the wild-type mice,

242 and S4) at a high TMP level (i.e., after the TMP jump) had many more proteins in the pH range of 4.0-

243 brane pressure (TMP) level (i.e., before the TMP jump) had larger gray intensities in the pH 5.5-7.0

244 Our results indicate that both the TMP and the foulant layer synergistically affected ARB r

245 bacterial strains engineered to express the TMP epitope improved immunotherapy in mice.

246 clindamycin group was similar to that in the TMP-SMX group (221 of 266 participants [83.1%] and 215 o

247 ndamycin group (15 of 221, 6.8%) than in the TMP-SMX group (29 of 215 [13.5%], P=0.03) or the placebo

248 (264 in the clindamycin group and 260 in the TMP-SMX group), including 155 children (29.6%).

249 5% in the clindamycin group and 88.2% in the TMP-SMX group; difference, -1.2 percentage points; 95% C

250 3% in the clindamycin group and 77.7% in the TMP-SMX group; difference, -2.6 percentage points; 95% c

251 n the TMP-SMX plus placebo group than in the TMP-SMX plus doxycycline group (122 [39%] vs 167 [53%]).

252 us placebo group and 21 patients (7%) in the TMP-SMX plus doxycycline group developed culture-confirm

253 16 patients (5%) in the TMP-SMX plus placebo group and 21 patients (7%) in the T

254 verse drug reactions were less common in the TMP-SMX plus placebo group than in the TMP-SMX plus doxy

255 9) in the placebo group and 0% (0/72) in the TMP-SMZ group (P < .001, log-rank test).

256 d 0%, 0%, 0%, 0%, 0%, and 1.4% (1/72) in the TMP-SMZ group (P < .001; log-rank test).

257 Cys) nucleophile engineered just outside the TMP-binding pocket of Escherichia coli dihydrofolate red

258 are better, and more homogeneously raise the TMP of tightly packed cells to a simulated electroporati

259 how the surrounding environment in which the TMP resides affects the pKa of these residues is unclear

260 iffusion and reveal that the mobility of the TMPs tested is subdiffusive, most likely caused by confi

261 O-Arylations with these TMP salts were demonstrated to be highly chemoselective.

262 These TMPs inhibit cytotoxic T lymphocyte (CTL) activity both

263 ble for de novo biosynthesis of thymidylate (TMP) and is essential for cell proliferation and surviva

264 d and randomly assigned 626 patients: 311 to TMP-SMX plus placebo and 315 to TMP-SMX plus doxycycline

265 ents: 311 to TMP-SMX plus placebo and 315 to TMP-SMX plus doxycycline.

266 First trimester exposure to TMP-SMX was associated with increased risk of neural tub

267 ings suggest that TMP-SMX is not inferior to TMP-SMX plus doxycycline for the oral phase of melioidos

268 tion of Shigella isolates with resistance to TMP-SMX was 40% among white persons, 58% among Hispanic

269 1 and XPF-1) imparted extreme sensitivity to TMP/UVA relative to wild-type animals, manifested as dev

270 ed a high selectivity and sensitivity toward TMP.

271 Trimethoprim (TMP) that specifically binds to eDHFR was linked to the

272 ed by the simple folate analog trimethoprim (TMP).

273 f sulfamonomethoxine (SMM) and trimethoprim (TMP) in egg yolk and white was measured during and after

274 and sulfadimethoxine, SDM) and trimethoprim (TMP).

275 the small-molecule antibiotic trimethoprim (TMP).

276 s controlled by the antibiotic trimethoprim (TMP).

277 azepine (CBZ), naproxen (NAP), trimethoprim (TMP), and sulfonamide antibiotics (SAs)) in synthetic hy

278 voltammetry in the presence of Trimethoprim (TMP) as template molecules.

279 (coop) = -2.9 kcal mol(-1)) of trimethoprim (TMP) binding to a bacterial dihydrofolate reductase (DHF

280 ics-based fitness landscape of trimethoprim (TMP) resistance for Escherichia coli dihydrofolate reduc

281 f the high affinity binding of trimethoprim (TMP) to Escherichia coli dihydrofolate reductase (eDHFR)

282 ryliodonium salts with the trimethoxyphenyl (TMP) moiety as dummy group.

283 diated degradation of 2,4,6-trimethylphenol (TMP) by (3)NOM* was significantly slowed at higher IS.

284 f the initial rate of 2,4,6-trimethylphenol (TMP) loss (R(TMP)) on dioxygen concentration was examine

285 f approximately 3 for 2,4,6-trimethylphenol (TMP) to a high of approximately 15 for 3,4-dimethoxyphen

286 of the probe compound 2,4,6-trimethylphenol (TMP), which is unaffected by DOM inhibition effects.

287 nstrate that use of 2,4,6-trimethylpyridine (TMP) as the base in peptide couplings produces glycopept

288 Here we have developed a novel and versatile TMP-AcBOPDIPY probe for selective and turn-on labeling o

289 onverted to a graphene-analogous deposit via TMP surfactant and a Zn phosphate molecular template.

290 ct liver stage Plasmodium parasites, whereas TMP-SMX prevents patent parasitemia.

291 ent or outpatient encounters associated with TMP diagnosis at least 30 days apart.

292 FR and its binary and ternary complexes with TMP and NADPH and made complementary thermodynamic measu

293 he efficacy and side-effects of TMP-SMX with TMP-SMX plus doxycycline for the oral phase of melioidos

294 th clindamycin (58 of 265 [21.9%]) than with TMP-SMX (29 of 261 [11.1%]) or placebo (32 of 255 [12.5%

295 Nine patients were treated with TMP-SMX and rifampin.

296 e relapsed and was successfully treated with TMP-SMX.

297 Treatment with TMP inhibited the growth and survival and impaired nucle

298 adoptive transfer of CTLs pre-cultured with TMPs from irradiated breast carcinoma cells increases tu

299 ontrol mice receiving CTLs pre-cultured with TMPs from untreated tumor cells.

300 ooth dehydrogenation when generated using Zn(TMP)2 2 LiCl as a base in the presence of excess ZnCl2 ,