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1 lity and repeatability of the developed EESI-TOF-MS were tested under complex dynamic and periodic ex
2 icability of two different platforms (LC-ESI-TOF MS and LC-ESI-IT MS) as powerful tools for the chara
3 lutive chromatographic method coupled to ESI-TOF MS (for initial characterisation purposes) and coupl
5 d extraction (UAE) and the platform HPLC-ESI-TOF-MS was employed to characterize these components in
9 zation time-of-flight mass spectrometry (ESI-TOF-MS) to derive the reaction mechanism and to obtain t
10 zation time-of-flight mass spectrometry (ESI-TOF-MS), thereby demonstrating the influence of differen
12 fied limits and the brain concentrations for TOF MS (51.1 +/- 4.4 pmol/mg) and FTICR MS (56.9 +/- 6.0
13 ography time-of-flight mass spectrometry (GC-TOF MS) and liquid chromatography Orbitrap mass spectrom
14 ography time-of-flight mass spectrometry (GC-TOF MS) and liquid chromatography Orbitrap mass spectrom
17 ography-time-of-flight mass spectrometry (GC-TOF-MS) based metabolomics combined with partial least s
20 th time-of-flight mass spectrometry (GC x GC-TOF-MS) was combined with conventional mono-dimensional
21 hy-time-of-flight mass spectrometry (GC x GC-TOF-MS), and their identity were confirmed by comparison
23 ography/time-of-flight mass spectrometry (GC/TOF-MS), here used to examine the S. cerevisiae metabolo
24 sample processing of data acquired by GCxGC-TOF MS for the identification of potentially novel persi
28 dentification power of PI coupled with GCxGC-TOF-MS is the first report covering volatiles to low-vol
29 aselines, and GC(2)MS is able to align GCxGC/TOF-MS data sets acquired under different experimental c
33 aphy time-of-flight mass spectrometry (GCxGC/TOF-MS) is superior for chromatographic separation and p
35 GC(2)MS then aligns the blobs of two GCxGC/TOF-MS data sets according to their distance and similar
36 ormance of GC(2)MS was evaluated using GCxGC/TOF-MS data sets of Angelica sinensis compounds acquired
38 olution time-of-flight mass spectrometer (HR TOF MS), under the challenging conditions of a flow-modu
44 time-of-flight mass spectrometry (LAESI-IMS-TOF-MS) was used for the analysis of synthetic polymers
46 on-trap time-of-flight mass spectrometer (IT-TOF-MS) for the separation and identification of constit
47 a time-of-flight mass spectrometer (UPLC-IT-TOF-MS) that allowed the characterization of the toxin p
49 hat accurately detects the pure ions of a LC/TOF-MS profile to extract pure ion chromatograms and det
50 ography/time-of-flight mass spectrometry (LC/TOF-MS) ion signals in a complex biological sample remai
52 zation time-of-flight mass spectrometry (LDI-TOF MS) studies of the crystalline samples show intense
68 grees C using a spectrophotometer) and MALDI-TOF MS (both the standard result output and by visual sp
69 standardized culture, extraction, and MALDI-TOF MS analysis, isolates were identified using score cu
70 value (NPV) of MALDI-TOF MS alone and MALDI-TOF MS coupled with UA were 86.6% versus 93.4% (chi(2) =
71 cation (CONV), (ii) manual plating and MALDI-TOF MS identification (MALDI), (iii) MALDI-TOF MS identi
73 ity and that the combination of UA and MALDI-TOF MS provided an accurate and rapid detection and iden
75 ant factors that must be considered as MALDI-TOF MS moves into applications beyond microbial identifi
76 (0.9%) isolates were misidentified by MALDI-TOF MS (including Aspergillus amoenus [n = 2] and Asperg
77 dilution of milks in water followed by MALDI-TOF MS analyses in the positive linear ion mode and usin
78 the substitution has been validated by MALDI-TOF MS analysis of the functionalized precursors and FT-
79 trometry (MS) types were identified by MALDI-TOF MS analysis, 53.5% isolates were MS4 and MS6, which
80 y testing of the samples identified by MALDI-TOF MS produced an overall categorical agreement of 99.2
82 ng bioconjugates were characterized by MALDI-TOF MS, differential scanning calorimetry (DSC), fluores
94 terial and yeast isolates prepared for MALDI-TOF MS identification can be repeatedly analyzed without
96 ieve a trustworthy identification from MALDI-TOF MS data, a significant amount of biomass should be c
97 e containers and obtained identifiable MALDI-TOF MS collagen fingerprints, all indicative of the same
98 I-TOF MS identification (MALDI), (iii) MALDI-TOF MS identification and early phase implementation of
99 elevant Nocardia spp. and to implement MALDI-TOF MS libraries developed by single laboratories across
100 ed characteristic isotopic patterns in MALDI-TOF MS, and both a fragmentation product y1 ion correspo
102 implementation of TLA (TLA1), and (iv) MALDI-TOF MS identification and late phase implementation of T
103 ty of the Bruker Biotyper and Vitek MS MALDI-TOF MS systems and their in vitro diagnostic (IVD), rese
104 red, demonstrate the value of this new MALDI-TOF MS method as an analytical tool for the identificati
105 s have been characterized by (1)H NMR, MALDI-TOF MS, steady-state absorption and emission spectroscop
106 dia isolates, and NIH and OSU Nocardia MALDI-TOF MS libraries were distributed to three centers.
107 supplementation of the Bruker Nocardia MALDI-TOF MS library with both the OSU and NIH libraries incre
108 and negative predictive value (NPV) of MALDI-TOF MS alone and MALDI-TOF MS coupled with UA were 86.6%
109 is study was to evaluate the impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with real-time
111 aluated the capacity of combination of MALDI-TOF MS and urine analysis (UA) for direct detection and
112 Our work highlights applications of MALDI-TOF MS beyond identification, focusing on mycobacterial
116 ee sites, while specificity and NPV of MALDI-TOF MS for males were significantly higher than those fo
118 s review discusses the various uses of MALDI-TOF MS for the identification and susceptibility testing
119 his work, we report the specificity of MALDI-TOF MS for the identification of 162 Mycobacterium speci
120 monstrate the promising application of MALDI-TOF MS in evaluating the photodynamic effect of each com
121 in the databases and in the ability of MALDI-TOF MS to rapidly identify slowly growing mycobacteria a
122 specificity study, the performance of MALDI-TOF MS was directly compared with that of 16S rRNA gene
124 peptides at other times of processing, MALDI-TOF MS was also employed as a fast and easier technique.
128 tion-time-of-flight mass spectrometry (MALDI-TOF MS) after enzymatic digestion of the polysaccharide
129 tion time of flight mass spectrometry (MALDI-TOF MS) analysis allowing in minutes the identification
132 tion-time of flight mass spectrometry (MALDI-TOF MS) and automated identification systems as well as
133 tion-time of flight mass spectrometry (MALDI-TOF MS) and BD Kiestra total laboratory automation (TLA)
134 tion-time of flight mass spectrometry (MALDI-TOF MS) and evaluated the capacity of combination of MAL
135 tion-time-of-flight mass spectrometry (MALDI-TOF MS) can be applied for the identification of pathoge
136 tion-time of flight mass spectrometry (MALDI-TOF MS) decreases the time to organism identification an
139 tion-time of flight mass spectrometry (MALDI-TOF MS) for group B streptococcus (GBS) identification,
140 tion-time of flight mass spectrometry (MALDI-TOF MS) for identification of Fusobacterium nucleatum su
141 tion-time of flight mass spectrometry (MALDI-TOF MS) for rapid organism identification and dedicating
142 tion-time of flight mass spectrometry (MALDI-TOF MS) for the identification of bacteria and yeasts is
143 tion time of flight mass spectrometry (MALDI-TOF MS) for the identification of Exophiala species.
144 tion-time of flight mass spectrometry (MALDI-TOF MS) for the identification of NTM isolated on RGM me
145 tion-time of flight mass spectrometry (MALDI-TOF MS) for yeast isolate identification, real-time PCR
146 tion-time of flight mass spectrometry (MALDI-TOF MS) has become the standard for routine bacterial sp
147 tion-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid and accurate method for i
148 tion-time of flight mass spectrometry (MALDI-TOF MS) has recently been reported to be a reliable and
149 tion-time of flight mass spectrometry (MALDI-TOF MS) has reduced the time to identification of cultur
150 tion-time of flight mass spectrometry (MALDI-TOF MS) has revolutionized clinical microbiology for iso
151 tion-time of flight mass spectrometry (MALDI-TOF MS) identification and broth microdilution phenotypi
152 tion-time of flight mass spectrometry (MALDI-TOF MS) identification, and score interpretation, using
153 tion-time of flight mass spectrometry (MALDI-TOF MS) identified Staphylococcus lugdunensis to be a mo
154 tion-time of flight mass spectrometry (MALDI-TOF MS) in clinical microbiology has revolutionized spec
155 tion-time of flight mass spectrometry (MALDI-TOF MS) in conjunction with active antimicrobial steward
156 tion-time of flight mass spectrometry (MALDI-TOF MS) in less than 15 min but is not optimized for the
158 tion time-of-flight mass spectrometry (MALDI-TOF MS) is frequently used for the characterization of c
160 tion time-of-flight mass spectrometry (MALDI-TOF MS) plates, termed fast lipid analysis technique or
161 tion time-of-flight mass spectrometry (MALDI-TOF MS) platforms in the medical microbiological practic
162 tion-time of flight mass spectrometry (MALDI-TOF MS) sample preparation methods, including the direct
163 tion-time of flight mass spectrometry (MALDI-TOF MS) system was able to identify S. delphini to the s
164 tion time-of-flight mass spectrometry (MALDI-TOF MS) target plates printed by FDM technology using co
165 sorption/ionization mass spectrometry (MALDI-TOF MS) that allows quantification of pure or mixed dete
166 tion-time of flight mass spectrometry (MALDI-TOF MS) to detect pKpQIL_p019 (p019)-an approximately 11
167 tion time of flight mass spectrometry (MALDI-TOF MS) with only 1 muL of sample in a fast (less than 1
168 tion-time of flight mass spectrometry (MALDI-TOF MS) with Sepsityper processing (Bruker Daltonics, Bi
169 tion-time of flight mass spectrometry (MALDI-TOF MS), and 16S rRNA partial genome sequence analysis w
170 tion-time of flight mass spectrometry (MALDI-TOF MS), gas chromatography (GC), SDS-PAGE, Toll-like re
171 tion-time of flight mass spectrometry (MALDI-TOF MS), sequencing of eight genes in the GPL locus, and
172 tion-time of flight mass spectrometry (MALDI-TOF MS), suspicious isolates are now routinely identifie
173 tion-time of flight mass spectrometry (MALDI-TOF MS), which has a limited capacity to identify biolog
174 tion-time of flight mass spectrometry (MALDI-TOF MS)-based identifications of the flown and stationar
183 me-of-flight tandem mass spectrometry (MALDI-TOF MS/MS), we now reveal that actually up to five fucos
185 ere identified by biochemical testing, MALDI-TOF MS, and 16S rRNA sequence analysis (179 isolates; 2
187 ynamic range and higher precision than MALDI-TOF MS, while still generating results in a similar time
189 to the species level, suggesting that MALDI-TOF MS is the best option for distinguishing members of
191 r aerobic actinomycetes using both the MALDI-TOF MS manufacturer's supplied database(s) and a custom
192 142,532.69, versus $68,886.51 with the MALDI-TOF MS method, resulting in a laboratory savings of $73,
193 he beads are directly dispensed on the MALDI-TOF MS target enabling the identification and sensitive
194 Plasmid identification using this MALDI-TOF MS method was accomplished in as little as 10 min fr
195 ociated polysaccharides (CWPS) through MALDI-TOF MS and methylation analysis, we report on three such
196 stent with bactericidal rates and thus MALDI-TOF MS might be able to replace the LB agar colony to ev
197 AMS intervention included: real-time MALDI-TOF MS pharmacist notification and prospective AMS provi
198 cobacteria require extraction prior to MALDI-TOF MS analysis, previously published protocols have bee
201 rowing organisms in BSCs and not using MALDI-TOF MS for identification until BTAs have been ruled out
203 l microbiology laboratories to utilize MALDI-TOF MS for the rapid identification of clinically releva
204 he impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with real-time, pharmacist-driven, antim
205 positive blood cultures identified via MALDI-TOF MS combined with prospective AMS intervention compar
206 ost of performing the bioMerieux Vitek MALDI-TOF MS with conventional microbiological methods to dete
207 gainst all Exophiala isolates in vitro MALDI-TOF MS successfully distinguished all 18 species and ide
208 ptibility testing might be useful when MALDI-TOF MS results in an organism identification, and it mig
211 WGS showed 99 and 93% concordance with MALDI-TOF MS at the genus and species levels, respectively.
212 al outcomes, rapid identification with MALDI-TOF MS combined with real-time AMS intervention is more
217 chniques such as RP-HPLC-UV, GFAAS and MALDI-TOF-MS allowed the identification of several proteins bo
218 thod for sialic acid stabilization and MALDI-TOF-MS analysis, to allow direct modification of impure
219 dies it was identified by SDS-PAGE and MALDI-TOF-MS that ZnPP formation takes place in myoglobin.
220 applied microchip electrophoresis and MALDI-TOF-MS-based glycomic procedures to 20 control serum sam
222 nd E nterobacter spp. were analyzed by MALDI-TOF-MS in negative ion mode to obtain glycolipid mass sp
224 e isolated, and structural analysis by MALDI-TOF-MS, GC-MS, and 2D NMR revealed that both were atypic
226 hed an expeditious method that couples MALDI-TOF-MS with a simple dilution method to quantify curcumi
227 from kinetic investigations and DSC-, MALDI-TOF-MS-, (1)H NMR-studies of linear polymers prepared in
228 onisation properties and resolution in MALDI-TOF-MS, these phosphopeptides were identified as suitabl
229 -assisted laser desorption/ionization (MALDI-TOF-MS) for determination of Cu, Fe, Mn and Zn and ident
231 B and 1.2 x 10(5) J/m(2) UVA), neither MALDI-TOF-MS nor RT-qPCR detected significant decreases in the
234 Following UV254 exposure, quantitative MALDI-TOF-MS detected significantly more RNA modifications tha
236 tion time-of-flight mass spectrometry (MALDI-TOF-MS) analysis of high abundance proteins is gaining p
237 tion Time of Flight Mass Spectrometry (MALDI-TOF-MS) biotyping to deliver rapid and accurate strain s
238 with time-of-flight mass spectrometry (MALDI-TOF-MS) has been used to analyse various molecules (incl
239 tion time-of-flight mass spectrometry (MALDI-TOF-MS) has successfully been used for the analysis of h
240 tion time-of-flight mass spectrometry (MALDI-TOF-MS) is a valuable tool for glycan characterization a
242 tion time-of-flight mass spectrometry (MALDI-TOF-MS) is the preferred instrumental platform for finge
243 tion time-of-flight mass spectrometry (MALDI-TOF-MS) method and corresponding mathematic matrix to de
247 ation with minimal side reactions: the MALDI-TOF-MS profiles obtained were in good agreement with hyd
248 cylglycerol) in complex mixtures using MALDI-TOF-MS with fractional factorial design (FFD) and Pareto
249 y RNA pulldown experiments followed by MALDI/TOF-MS analysis, we identified heterogeneous nuclear rib
252 for wide m/z range applications, whereas MR-TOF MS can provide advantages in a "zoom-in" mode in whi
253 prising both conventional time-of-flight MS (TOF-MS) and nano-electromechanical systems-based MS (NEM
254 time-of-flight mass spectrometry (IR-MALDI-o-TOF MS) in combination with collision-induced dissociati
255 In this paper, we present results of a PI-TOF-MS study at the Advanced Light Source at Lawrence Be
256 ble to those with other synchrotron-based PI-TOF-MS reactors, and it is anticipated that this high pr
257 S research to include synchrotron sourced PI-TOF-MS required a radical reconception of the shock tube
258 ization time-of-flight mass spectrometry (PI-TOF-MS) is an important technique in combustion chemistr
261 is was performed using hybrid quadrupole (Q) TOF MS with an atmospheric pressure chemical ionization
264 ole time-of-flight mass spectrometry (HPLC-Q-TOF MS) with univariate and multivariate statistical ana
268 upole time-of-flight mass spectrometry (LC-Q-TOF-MS) was utilized to acquire metabolic profiles of mu
273 led rhizome was carried out utilizing UPLC-Q-TOF-MS(E), LC-QqQ-MS and GC-MS techniques and evaluated
275 This study aimed to identify by UPLC-PDA-Q/TOF-MS and quantify by UPLC-PDA phenolic compounds (26 f
277 tored by UV-Vis spectroscopy and LC-ESI-(Qq)-TOF-MS-DAD, enabling the identification of some intermed
278 PD studies that the sensitivity of the REMPI-TOF-MS is comparable to commercial EI-Q-MS solutions and
279 al rituximab sample shows that online sLCxLC-TOF-MS can be used to rapidly characterize mAb samples,
280 med with a time-of-flight mass spectrometer (TOF-MS) to allow for a comprehensive evaluation of the o
282 ionization time-of-flight mass spectrometry (TOF-MS) allows the detection of thousands of compounds.
283 apply LIAD time-of-flight mass spectrometry (TOF-MS) to the natural biochromophores chlorophyll, hemi
284 gh sensitivity and high mass accuracy of the TOF-MS revealed the presence of more than 70 glycans.
285 s, LC-MS-based quantification, and MALDI TOF-TOF MS analyses, we found that MaMmp10 catalyzes the met
287 time-of-flight mass spectrometry (MALDI-TOF/TOF MS) were used to assess the different protein expres
290 /time-of-flight mass spectrometry (MALDI-TOF/TOF-MS) for sequential identification of the peptide.
294 paper, the potential of Synapt G2-S (Q-TWIM-TOF MS) has been investigated for sensitive and specific
296 aphy/time-of-flight mass spectrometry (UHPLC/TOF-MS), was used for the analysis of 60 pesticides in v
300 S(+) radical scavenging assay and LC-MS with TOF-MS for compositional analysis of the most potent ant