ライフサイエンスコーパス: TOFMS

1 Particularly, GC(3)/TOFMS achieved a combined (2)D x (3)D peak capacity rang

2 The GC(3)/TOFMS instrument experimentally achieved total peak capa

3 f-flight mass spectrometric detection (GC(3)/TOFMS) is described.

4 the 44 peaks, 25 were identified by use of a TOFMS library created for this study; another 11 were id

5 The unique capability of a TOFMS to measure fast transient signals and to still cov

6 nd retrofitted to an orthogonal acceleration TOFMS.

7 mpling duty cycle of orthogonal acceleration TOFMS.

8 atographic separation of most compounds, and TOFMS allows mass spectral deconvolution of coeluting co

9 The geometric mean LOQs using the qMS and TOFMS were 4 and 3 ng/g ginseng, respectively.

10 e, we applied MCF derivatization and GC-APCI-TOFMS to the detection of changes in abundance of metabo

11 fference) that they could not be resolved by TOFMS alone.

12 ne chemical ionization mass spectrometry (CI-TOFMS) where formamide, isocyanic acid as well as higher

13 IMS-in-source collision induced dissociation-TOFMS (FISCID-MS) method requires only minor modificatio

14 ation-time-of-flight mass spectrometry (ENCI-TOFMS).

15 lipid biochemical analysis, and UPLC-ESI(+/-)TOFMS for lipidomic profiling.

16 signal intensity of m/z in sheathless CE/ESI-TOFMS at pH 6.7 is approximately 50 times higher than th

17 ion time-of-flight mass spectrometry (CE/ESI-TOFMS).

18 hanolic extraction combined with a RP-LC-ESI-TOFMS profiling method was implemented.

19 of-flight mass spectrometry detector (LC-ESI-TOFMS) to identify fluorinated compounds in natural wate

20 using internal standards in the on-line ESI-TOFMS process.

21 lues are then obtained upon the basis of ESI-TOFMS so that an image of isolectric point (pI) versus M

22 The ESI-TOFMS analysis of SLTx-AB(5) revealed the complex remain

23 eved by coupling pressure-assisted CE to ESI-TOFMS using the described sheathless electrospray emitte

24 entional sample preparations using UHPLC-ESI-TOFMS analyses.

25 Compared with UHPLC-ESI-TOFMS, analysis by the nanoplatform enabled detection of

26 ESI/TOFMS confirmed a good method specificity, i.e., without

27 amples and to enhance column selectivity for TOFMS characterization in cases in which peak overlap is

28 C/min programming rate were explored for GC-TOFMS, specifically a 20 m, 100 mum inner diameter (i.d.

29 Analysis of GC-TOFMS data by this method produces what is referred to a

30 resolution GC x GC-TOFMS against that of GC-TOFMS for metabolomics analysis of two different plasma

31 To optimize GC-TOFMS separations collected with a commercial instrument

32 ography-time-of-flight mass spectrometry (GC-TOFMS) and applied to the fast separation of complex sam

33 ography time-of-flight mass spectrometry (GC-TOFMS) is presented that significantly facilitates separ

34 flight high-resolution mass spectrometry (GC-TOFMS) with electron ionization (EI) and chemical ioniza

35 nd GC x GC-TOFMS outperformed traditional GC-TOFMS in terms of separation performance and metabolite

36 d the performance of high resolution GC x GC-TOFMS against that of GC-TOFMS for metabolomics analysis

37 These results demonstrate that GC x GC-TOFMS analysis in combination with a random forest techn

38 matched controls, were subjected to GC x GC-TOFMS analysis.

39 In this paper, we propose Py-GC x GC-TOFMS as an example of one such technique.

40 analyte signals in a subsection of a GC x GC-TOFMS chromatogram (i.e., for analyses when identities o

41 n of signal from a target analyte in GC x GC-TOFMS data (i.e., for an analysis in which the identity

42 sses algorithmically reduces complex GC x GC-TOFMS data sets to find class distinguishing chemical fe

43 We use real experimental GC x GC-TOFMS data to demonstrate the broad applicability of the

44 an appropriate number of factors in GC x GC-TOFMS data, demonstrated for a target analyte of interes

45 Overall, our application of GC x GC-TOFMS identified key metabolites in complex plasma matri

46 We conclude that Py-GC x GC-TOFMS is a promising technique that can potentially be u

47 We found GC x GC-TOFMS outperformed traditional GC-TOFMS in terms of sepa

48 GC x GC-TOFMS proved to be a method that not only can be used as

49 predicted by N-PLS and identified by GC x GC-TOFMS were confirmed using quantitative structure-activi

50 hy/time-of-flight mass spectrometry (GC x GC-TOFMS) data and applied to the investigation of the chan

51 hy-time-of-flight mass spectrometry (GC x GC-TOFMS) data set to the bioassay data obtained from norma

52 hy time-of-flight mass spectrometry (GC x GC-TOFMS) enabled us to identify 32 new molecules produced

53 th time-of-flight mass spectrometry (GC x GC-TOFMS) is a versatile instrumental platform capable of c

54 s with multichannel detection (e.g., GC x GC-TOFMS) or multiple samples (or replicates) of 2D data.

55 hy time-of-flight mass spectrometry (GC x GC-TOFMS) was applied to 210 products (154 recycled, 56 vir

56 to time-of-flight mass spectrometry (GC x GC-TOFMS) was used with discovery-based data mining algorit

57 - time of flight mass spectrometry (GC x GC-TOFMS) with sample introduction using headspace solid ph

58 th time-of-flight mass spectrometry (GC x GC-TOFMS).

59 th time-of-flight mass spectrometry (GC x GC-TOFMS).

60 th time-of-flight mass spectrometry (GC x GC-TOFMS).

61 th time-of-flight mass spectrometry (GC x GC-TOFMS).

62 flight mass spectrometric detection (GC x GC-TOFMS).

63 time-of-flight mass spectrometry (TD-GC x GC-TOFMS).

64 t with several target analytes using GC x GC-TOFMS.

65 atome was investigated using HS-SPME-GC x GC-TOFMS.

66 tes, were exclusively detected using GC x GC-TOFMS.

67 rming the feasibility of the new dynHS-TD-GC/TOFMS approach for routine analysis.

68 ime-of-flight mass spectrometry (dynHS-TD-GC/TOFMS) for the simultaneous quantitation of these boar t

69 GC x GC/TOFMS allowed five and six co-elutions to be resolved, i

70 GC x GC/TOFMS analyses resulted in 145 identified compounds and

71 different chromatographic platforms (GC x GC/TOFMS, GC-O-OSME, GC-FID and GC/MS).

72 t, and HVHF fluids had been available, GCxGC-TOFMS might have fingerprinted the contamination source.

73 then applied to gasoline, followed by GCxGC-TOFMS analysis of the original and brominated gasoline.

74 d to contain 44 terpenes identified by GCxGC-TOFMS.

75 Following data collection, GCxGC-TOFMS chromatograms were analyzed by Fisher ratio softwa

76 workflow was demonstrated on data from GCxGC-TOFMS.

77 research was to develop a nontargeted GCxGC-TOFMS approach to characterize petroleum metabolites in

78 aphy time-of-flight mass spectrometry (GCxGC-TOFMS) with discovery-based analysis is reported.

79 d to time-of-flight mass spectrometry (GCxGC-TOFMS), an unresolved complex mixture of organic compoun

80 aphy time-of-flight mass spectrometry (GCxGC-TOFMS).

81 conducted on 129 samples using HS-SPME-GCxGC-TOFMS.

82 e-of-flight mass spectrometry (HS-SPME/GCxGC-TOFMS).

83 This GCxGC-TOFMS data set was then submitted to the supervised disc

84 GCxGC/TOFMS allowed identification of 220 compounds including

85 GCxGC/TOFMS allows more detailed study of the volatile profile

86 GCxGC/TOFMS analyses and QDA have shown that a larger spacing

87 of-flight mass spectrometry detection (GCxGC/TOFMS) and chemometric tools.

88 f-flight mass spectrometric detection (GCxGC/TOFMS) proved to be appropriate for this first simultane

89 of-flight mass spectrometry detection (GCxGC/TOFMS) was used to analyse the volatiles in five types o

90 A detailed examination of GCxGC/TOFMS data showed that the use of one-dimensional gas ch

91 with time-of-flight mass spectrometry (GCxGC/TOFMS) on plasma from patients with S. Typhi and S. Para

92 profile and sensory perception through GCxGC/TOFMS, QDA, GC-FID, GC/MS, and GC-O.

93 on of some of them was possible due to GCxGC/TOFMS performance.

94 00 scans/s or greater) of current generation TOFMS detectors.

95 The combination of the HPLC-FTMS(n) and HPLC-TOFMS-SPE-NMR platforms results in the efficient identif

96 onance spectroscopy (NMR) measurements (HPLC-TOFMS-SPE-NMR).

97 ne-dimensional (1D)-(1)H NMR spectra of HPLC-TOFMS-SPE-trapped compounds, we elucidated the structure

98 Second, GC x GC-HR-TOFMS data were processed with the spectral analysis too

99 Mean recoveries using GC-HR-TOFMS were 93, 85, and 81% with mean standard deviations

100 tion time-of-flight mass spectrometry (GC-HR-TOFMS).

101 time-of-flight mass spectrometry (GC x GC-HR-TOFMS).

102 the analysis of PPO samples using GC x GC-HR-TOFMS, making the process faster and more powerful.

103 HT-TOFMS was able to sample peaks having widths in the mill

104 ansform time-of-flight mass spectrometry (HT-TOFMS) is a promising detector for any capillary-format

105 urized-capillary electrophoresis (pCE) to HT-TOFMS.

106 n suspension for THP-1 cells and with LA-ICP-TOFMS analysis of adherent M0 cells grown on chambered g

107 hat uses the ratio of IS elements and LA-ICP-TOFMS analysis.

108 rates the potential of low-dispersion LA-ICP-TOFMS as a rapid and powerful tool for label-free single

109 flow for semiquantitative analysis by LA-ICP-TOFMS based on multi-element gelatin micro-droplet stand

110 he visual interpretation of the data, LA-ICP-TOFMS data were projected onto the mu-CT voxels represen

111 LA-ICP-TOFMS element mapping of conventionally dried samples ca

112 s performed to spatially align the 2D LA-ICP-TOFMS images relative to the corresponding slices of the

113 The multielement LA-ICP-TOFMS imaging approach enabled (i) the detection of asbe

114 To demonstrate the potential of 3D LA-ICP-TOFMS imaging, high-resolution multielement images of a

115 thin sections that were subjected to LA-ICP-TOFMS imaging.

116 LA-ICP-TOFMS results correlated to Perls' Prussian blue and his

117 resolution capabilities of this novel LA-ICP-TOFMS setup may become an important clinical tool for si

118 sma-time-of-flight mass spectrometry (LA-ICP-TOFMS) and laboratory-based absorption microcomputed tom

119 sma time-of-flight mass spectrometry (LA-ICP-TOFMS) enables high-resolution mapping of elemental dist

120 sma time-of-flight mass spectrometry (LA-ICP-TOFMS) for high-speed, high-resolution, quantitative thr

121 sma time-of-flight mass spectrometry (LA-ICP-TOFMS) imaging is presented for multielement analysis of

122 sma time-of-flight mass spectrometer (LA-ICP-TOFMS) is an upcoming method for rapid quantitative elem

123 sma time-of-flight mass spectrometry (LA-ICP-TOFMS) to analyze human malignant pleural mesothelioma (

124 sma-time-of-flight mass spectrometry (LA-ICP-TOFMS) workflow was implemented for quantitative single-

125 with both fluorescence microscopy and LA-ICP-TOFMS, enabling cross-validation of membrane labeling an

126 s, and the use of ICP time-of-flight-MS (ICP-TOFMS) allows one to simultaneously monitor the entire e

127 distributions in mass and size using SP ICP-TOFMS.

128 he coupling of OF2i with SP Raman and SP ICP-TOFMS.

129 es of interest allows for multiplexed sp-ICP-TOFMS experiments utilizing elemental fingerprinting of

130 plasma time-of-flight mass spectrometer (ICP-TOFMS) is described.

131 plasma time-of-flight mass spectrometry (ICP-TOFMS) enables monitoring of elements from the entire ma

132 plasma-time-of-flight-mass spectrometry (ICP-TOFMS) to harness their complementary technology-specifi

133 plasma-time-of-flight mass spectrometry (ICP-TOFMS) to provide full-spectrum elemental imaging at hig

134 The ability of the ICP-TOFMS to produce complete elemental mass spectra at high

135 laser-spot diameter of 5 mum coupled to ICP-TOFMS.

136 um i.d. RTX-5 column with a LECO Pegasus III TOFMS.

137 obility-time-of-flight mass spectrometry (IM-TOFMS) was used to identify and correlate response ions

138 value-added information provided by UPLC-IM-TOFMS makes it a promising analytical technique for anal

139 ty time-of-flight mass spectrometry (UPLC-IM-TOFMS) to corroborate the separation of distinct NA spec

140 ty time-of-flight mass spectrometry (UPLC-IM-TOFMS), integrating traveling wave ion mobility spectrom

141 ions were separated and identified using IM-TOFMS.

142 y advantage of this strategy is that the IM/ TOFMS approach allows the relative abundances of individ

143 erent sequences are assessed by comparing IM/TOFMS data for those components that pass through the co

144 obility/time-of-flight mass spectrometry (IM/TOFMS) analysis has been used to investigate the binding

145 The MP IMS-TOFMS instrument has been shown to reliably detect pepti

146 ometry-time-of-flight mass spectrometry (IMS-TOFMS) has been increasingly used in analysis of complex

147 an analog-to-digital converter, into the IMS-TOFMS system for the high-throughput analysis of highly

148 A major challenge is to transform IMS-TOFMS to a high-sensitivity, high-throughput platform, f

149 cover a broad range of polarity using MALDI TOFMS.

150 assisted laser desorption-ionization (MALDI) TOFMS peptide mapping and intact MW so that a standard m

151 Transfer into the elution buffer and MALDI-TOFMS detection was achieved from 5 microL of starting s

152 this first-time coupling of ThFFF and MALDI-TOFMS, compatibility issues were addressed and optimum c

153 n the MW distribution data obtained by MALDI-TOFMS and ThFFF.

154 ration by ThFFF and analyzed either by MALDI-TOFMS or reinjection into the ThFFF system.

155 actions were collected and analyzed by MALDI-TOFMS to determine the molecular weights and peptide map

156 ose beads and subsequently analyzed by MALDI-TOFMS using a curved-field reflectron.

157 ted analyte can be studied directly by MALDI-TOFMS, or subjected to proteolytic digestion for protein

158 wash was concentrated and analyzed by MALDI-TOFMS.

159 f purified proteins were determined by MALDI-TOFMS.

160 re followed by delayed extraction (DE) MALDI-TOFMS is presented.

161 microfabricated PCR instrument and DE-MALDI-TOFMS, a complete genotyping assay can be performed in u

162 al composition fractions essential for MALDI-TOFMS analyses.

163 e particularly challenging polymer for MALDI-TOFMS analysis is linear copolymers of vinylidene fluori

164 from 1-10 ThFFF runs were combined for MALDI-TOFMS analysis.

165 Sample preparation for MALDI-TOFMS was enhanced through the use of hydrophobic/hydrop

166 On the other hand, MALDI-TOFMS's ability to directly measure molecular weight all

167 zed previously by solution preparation MALDI-TOFMS, were used to evaluate the various solvent-free pr

168 ethods were developed to allow routine MALDI-TOFMS analyses of polystyrene polymers up to 575 kDa.

169 tion time-of-flight mass spectrometer (MALDI-TOFMS) apparatus and the on-chip digestion followed by e

170 tion time-of-flight mass spectrometry (MALDI-TOFMS) have been coupled to yield a powerful combination

171 tion time-of-flight mass spectrometry (MALDI-TOFMS) method was developed for the analysis of underiva

172 tion time-of-flight mass spectrometry (MALDI-TOFMS) sample preparation methods for the characterizati

173 tion time-of-flight mass spectrometry (MALDI-TOFMS) targets.

174 tion time-of-flight mass spectrometry (MALDI-TOFMS), this method has lent itself well to the analysis

175 tion-time-of-flight mass spectrometry (MALDI-TOFMS).

176 tion time-of-flight mass spectrometry (MALDI-TOFMS).

177 tion time-of-flight mass spectrometry (MALDI-TOFMS).

178 tion time-of-flight mass spectrometry (MALDI-TOFMS).

179 y techniques, but this work shows that MALDI-TOFMS using DCTB has advantages over these techniques, p

180 The application of ThFFF/MALDI-TOFMS to polydisperse polymers and polymer mixtures was

181 Progress in high-throughput MALDI-TOFMS analysis, especially in proteome applications, req

182 ein:matrix ratios, we were able to use MALDI-TOFMS to detect four bacterially expressed hydrophobic p

183 ependent analysis of methylation using MALDI-TOFMS clearly showed that both the presence and relative

184 us lots of a VDF-co-CTFE polymer using MALDI-TOFMS.

185 vered that analysis of VDF-co-CTFE via MALDI-TOFMS is a problem that can be solved through the applic

186 t is demonstrated that NP RP HPLC with MALDI-TOFMS detection may serve as a rapid means of detecting

187 The GC-MPT-TOFMS system offered equal sensitivity for I, Br, and Cl

188 The GC-MPT-TOFMS system offered excellent stability over the course

189 yze urine by splitless nanoflowUHPLC-nanoESI-TOFMS (nUHPLC-nESI-TOFMS) after preconcentration by soli

190 ty arising from use of splitless nUHPLC-nESI-TOFMS analyses of SPE-concentrated samples represents a

191 Analyses of SPE preparations by nUHPLC-nESI-TOFMS revealed excellent retention time repeatability wi

192 ess nanoflowUHPLC-nanoESI-TOFMS (nUHPLC-nESI-TOFMS) after preconcentration by solid-phase extraction

193 tification of potential sources, nontargeted TOFMS analysis, molecular feature extraction (MFE) of sa

194 portion of the eluent (10%) was taken for oa-TOFMS for identification.

195 sion because it extends the dynamic range of TOFMS measurements, especially for transient analyses.

196 Analyte desorption and the subsequent PI-TOFMS detection step only lasts ten seconds.

197 tion time-of-flight mass spectrometry (TD-PI-TOFMS).

198 desorbed and directly transferred to the PI-TOFMS ion source.

199 n single-particle inductively coupled plasma TOFMS (spICP-TOFMS).

200 tal LA signal within 9 ms, and the prototype TOFMS instrument enables simultaneous and representative

201 The key volatiles were identified by PTR-TOFMS.

202 With PTR-TOFMS, 101 volatile compounds were identified as total s

203 acteristic fragmentation pattern by hybrid Q-TOFMS offers a distinct advantage for the identification

204 ed di- and triacylglycerol profiling by LC/Q-TOFMS yielded successful differentiation of the oils.

205 leration time-of-flight mass spectrometry (Q-TOFMS).

206 igh-throughput ultra HPLC (UHPLC)-quadrupole TOFMS (qTOFMS) method, processed to systematically infer

207 ween 40 pairs of simultaneous 5-min GC-REMPI-TOFMS measurements of 1,2,4-trichlorobenzene and 5 min c

208 The GC-REMPI-TOFMS system can be used to provide frequent measures of

209 - time-of-flight mass spectrometry (GC-REMPI-TOFMS) system were compared over 5-min periods with conv

210 Furthermore, the NTD-REMPI-TOFMS setup was tested for breath gas taken from a mecha

211 tion time-of-flight mass spectrometry (REMPI-TOFMS) technique has been applied to the exhaust gas str

212 EMPI time-of-flight mass spectrometry (REMPI-TOFMS).

213 The high isomer selectivity of the REMPI-TOFMS instrument provided data for individual xylene iso

214 ing a GC column separator ahead of the REMPI-TOFMS.

215 resolution) as demonstrated here using REMPI-TOFMS.

216 latile organic compounds obtained with REMPI-TOFMS and conventional extractive sampling.

217 the sample introduction techniques for REMPI/TOFMS, the analyte molecules are adsorbed at the tip of

218 tion/time-of-flight mass spectrometry (REMPI/TOFMS) was developed for the analysis of product ions fo

219 d with the time-of-flight mass spectrometer (TOFMS) and flow modulator.

220 sor into a time-of-flight mass spectrometer (TOFMS) for simultaneous thermal and speciation measureme

221 celeration time-of-flight mass spectrometer (TOFMS) is explored for elemental analysis.

222 reflectron time-of-flight mass spectrometer (TOFMS) that provides a mass spectrum at every pixel of a

223 resolution time-of-flight mass spectrometer (TOFMS) that provides improved selectivity and accurate e

224 led plasma time-of-flight mass spectrometer (TOFMS) to a traditional CFA system.

225 faced to a time-of-flight mass spectrometer (TOFMS).

226 (CID) and time-of-flight mass spectrometry (TOFMS) analysis.

227 celeration time-of-flight mass spectrometry (TOFMS) based on the superimposition of a magnetic field

228 GC(3) with time-of-flight mass spectrometry (TOFMS) detection using a P(M) of 100 ms applied between

229 on (MALDI) time-of-flight mass spectrometry (TOFMS) following separation by reversed-phase high-perfo

230 coupled to time-of-flight mass spectrometry (TOFMS) for the detection of halogenated hydrocarbons sep

231 resolution time-of-flight mass spectrometry (TOFMS) for the identification of bioactives.

232 (GC x GC)-time-of-flight mass spectrometry (TOFMS) has been used to improve accurate metabolite iden

233 In time-of-flight mass spectrometry (TOFMS), ion detection is often achieved via electron mul

234 d to REMPI time-of-flight mass spectrometry (TOFMS).

235 As determined by spICP-TOFMS, Zn in the fruit was not in the NP form.

236 water, and suspensions are analyzed by spICP-TOFMS.

237 In spICP-TOFMS, highly time-resolved ion signals are recorded and

238 ated multi-element particle finding in spICP-TOFMS.

239 We evaluate the matrix tolerance of spICP-TOFMS with online microdroplet calibration through the a

240 asma time-of-flight mass spectrometry (spICP-TOFMS) is a powerful analytical technique for quantifyin

241 asma time-of-flight mass spectrometry (spICP-TOFMS) to measure and classify individual Ti-containing

242 asma time-of-flight mass spectrometry (spICP-TOFMS) was used to identify TiO(2) ENMs in soil.

243 asma time-of-flight mass spectrometry (spICP-TOFMS).

244 icle inductively coupled plasma TOFMS (spICP-TOFMS).

245 In previous research, we demonstrated that TOFMS signals acquired with fast ADC follow a compound P

246 The TOFMS instrument uses time-array detection to obtain up

247 The TOFMS was operated with a spectral acquisition rate of 2

248 adjusted to enhance the capabilities of the TOFMS detector.

249 d with the 0.1 ms temporal resolution of the TOFMS provides a new measurement capability and insight

250 corporated into the extraction region of the TOFMS system to provide sample heating and thermal infor

251 /min, due to the flow rate constraint of the TOFMS).

252 rage and rapid simultaneous detection of the TOFMS, the element composition of individual particles c

253 provide a narrow injection pulse, while the TOFMS provided a data collection rate of 500 Hz, initial

254 hermal and flow modulation, coupled with the TOFMS and/or FID to demonstrate compatibility with all t

255 eparation typically is not required with the TOFMS detection, and a pressure-tunable column ensemble

256 metry-time-of-flight mass spectrometry (TIMS-TOFMS) has been developed to achieve fast enantiomeric s

257 Analysis by UHPLC-TOFMS confirmed that the SILAAs were incorporated into p

258 lustrated using both 600-MHz 1H NMR and UPLC-TOFMS data obtained from control rat urine samples (n =

259 ectivities in the 3D separation coupled with TOFMS are illustrated through the separation and detecti