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1 B3 is an agonist of a Caenorhabditis elegans TRPV channel.
2 modulating the activity of calcium-selective TRPV channels.
3 ructural features contribute to diversity of TRPV channels.
4 ecular mechanism underlying NA regulation of TRPV channels.
5 l borate (2-APB), a common agonist for these TRPV channels.
6 ation threshold of gating elements shared by TRPV channels.
7 ization may be conserved in the subfamily of TRPV channels.
8 t is known to be an effective blocker of all TRPV channels.
9 e by vanilloid transient receptor potential (TRPV) channels.
10 intraflagellar transport and the OCR-2/OSM-9 TRPV channel act in concert, regulating two layers of ac
12 ans and Drosophila, serving as an agonist of TRPV channels affecting sensory neurons and mimicking th
14 s well as the orthologous Drosophila Nan-Iav TRPV channel, and we examine stoichiometry of subunit as
15 our understanding of ligand interaction with TRPV channels, and the availability of purified human TR
18 stinct mechanotransduction channels and that TRPV channels contribute to encoding and transmitting in
19 arbon polyunsaturated fatty acids (PUFAs) in TRPV channel-dependent olfactory and nociceptive behavio
20 ; however, the molecular mechanisms by which TRPV channels establish precise and robust temperature s
24 , revealing modality-specific mechanisms for TRPV channel function in the regulation of C. elegans ch
25 o further understand the structural basis of TRPV channel function, we determined the structure of fu
27 s provide a foundation to further understand TRPV channel gating, their divergent physiological funct
28 ocr-2, since mutants lacking npr-1 and both TRPV channels had more severe defects in heat avoidance
31 transient receptor potential vanilloid-type (TRPV) channels in insects, likely form a heteromeric cha
32 the putative selectivity filter of OSM-9, a TRPV channel, in osmotic avoidance behaviour of Caenorha
34 d influx of Ca(2+) that was abolished by the TRPV channel inhibitor, ruthenium red, or in tubules iso
35 ve effects were blocked by co-injection of a TRPV channel inhibitor, which are thought to function as
37 he Transient Receptor Potential Vanilloid 1 (TRPV) channel is activated by an array of stimuli, inclu
38 of corresponding residues within two related TRPV channels leads to comparable effects on their activ
39 d support cells, that it is not required for TRPV channel localization, and that it is not essential
40 o acid point mutation in OCR-2 that disrupts TRPV channel-mediated gene expression, but does not decr
41 ate that mechanosensory neurons expressing a TRPV channel nanchung, located in the antennae and chord
47 er show that p38/MAPK signals to AKT and the TRPV channel OSM-9, a sensory channel in ASH neurons.
49 neither of these genes, but does require the TRPV channel osm-9, which is dispensable for associative
51 the transient receptor potential vanilloid (TRPV) channels OSM-9 and OCR-2 selectively restore grk-2
53 nants, and specific functional properties of TRPV channel proteins may be selectively conserved acros
54 ealth of structures, many aspects concerning TRPV channels remain poorly understood, including the po
56 protein in the vanilloid receptor subfamily (TRPV) channel subunit, Nanchung (NAN), is localized to t
57 sults identify a specific set of heteromeric TRPV channels that redundantly regulate neuroendocrine f
60 (TRPV2) is an intracellular Ca(2+)-permeable TRPV channel upregulated by NGF via the mitogen-activate