ライフサイエンスコーパス: TTF

1 TTF and OS were comparable in both arms.

2 TTF was independently associated with age, beta-2M, perc

3 TTF was longer in the GD arm.

4 (TTF)(2) [Co(pdms)(2) ] (2-Co) is an excellent building b

5 TTF-1 is amplified in lung cancers, suggesting that it i

6 TTF-1 knockdown and overexpression studies showed that T

7 ification of thyroid transcription factor 1 (TTF-1 or NKX2-1) biochemical activity as a transcription

8 hat PPFP and thyroid transcription factor 1 (TTF-1) physically interact, and that these transcription

9 d binding of thyroid transcription factor 1 (TTF-1) to an upstream response element (TTF-1-binding el

10 f endogenous thyroid transcription factor 1 (TTF-1/Nkx2.1) to the miR-29ab1 promoter in HFL type II c

11 ulator gene, Thyroid Transcription Factor-1 (TTF-1, also known as NKX2-1), is used as a marker by pat

12 A binding of thyroid transcription factor-1 (TTF-1/Nkx2.1), a master regulator of lung development.

13 e-ion magnet (SIM), (TTF)(2) [Co(pdms)(2) ] (TTF=tetrathiafulvalene and H(2) pdms=1,2-bis(methanesulf

14 ,5-dioxynaphthalene (DNP) unit, as well as a TTF unit, encircled by a CBPQT(4+) ring.

15 activity does not appear to be mediated by a TTF-1-imposed alteration on nucleotide excision repair.

16 , that contain a BIPY(2+) unit with either a TTF or DNP unit, is investigated.

17 The first example of a TTF-based self-assembled cage has been produced from thi

18 ed significantly less often in grafts with a TTF with low flow (259 of 363 [71.3%]) than in those wit

19 icenter [TTF](*+)...[TTF](*+) bonds when all TTF groups host a 1+ au of charge, as in clip2(4+).

20 Although TTF-1 is amplified in primary human lung cancers, it inh

21 lower than those reported for the analogous TTF materials.

22 However, in multivariate analysis, TTF was not an independent risk factor for VA <0.3 (odds

23 nding between surface-adsorbed CBPQT(4+) and TTF.

24 miR-29ab1 promoter in HFL type II cells, and TTF-1 increased miR-29ab1 promoter-driven luciferase act

25 n of the CBPQT(4+) rings between the DNP and TTF recognition sites in the GSCC.

26 Furthermore, the [M(pdms)(2) ](n-) donor and TTF(.+) acceptor are not segregated but strongly interac

27 OS and TTF were not affected by the occurrence of irAEs or the

28 as independent prognostic factors for OS and TTF.

29 roid-specific transcription factors Pax8 and TTF-1, leading to expression of the thyroid-specific tar

30 factor NK2 homeobox 1 (NKX2-1; also known as TTF-1).

31 e findings identify miR-29 family members as TTF-1-driven mediators of SP-A expression and type II ce

32 triangular magnetic lattice of spin-1/2 BEDT-TTF dimers that provides a prime example of a spin liqui

33 etween the n-orbitals of the S atoms in BEDT-TTF of the BEDT-TTF/C60 layer and the pi* orbitals of C

34 The layered molecular system kappa-(BEDT-TTF)(2)Cu(2)(CN)(3) is a Mott insulator with an almost i

35 organic molecular metals in the kappa-(BEDT-TTF)(2)X family, we reveal how the Nernst effect, a sens

36 The Mott-insulating state in the kappa-(BEDT-TTF)2X organic molecular metals can be tuned, without do

37 ng in a centimeter-sized free-standing (BEDT-TTF)C60 charge-transfer single crystal is demonstrated.

38 bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF)/C60 and poly(3-dodecylthiophene-2,5-diyl) (P3DDT)/C

39 itals of the S atoms in BEDT-TTF of the BEDT-TTF/C60 layer and the pi* orbitals of C atoms in C60 of

40 EGJ cancer demonstrated significantly better TTF than did ECX.

41 ns, of dimers of bis-tetrathiafulvalene (bis-TTF)-functionalized diphenylglycoluril molecular clips (

42 a 1:1 stoichiometry between the anion-bound TTF-C4Ps and the complexed fullerenes.

43 ports the first miRNAs directly regulated by TTF-1 and clarifies how TTF-1 controls HMGA2 expression.

44 s revealed a high affinity of the calixarene-TTF receptors for planar electron-deficient guests, lead

45 In lung cancers, TTF-1 displays seemingly paradoxical activities.

46 g mixed-valence (TTF)2*+ and radical-cation (TTF*+)2 states inside the 'molecular flasks.' The experi

47 in the two catenanes, the radical cationic (TTF(*+))2 dimer in the [2]catenane occurs only fleetingl

48 ring system to either its radical cationic (TTF*+) or dicationic (TTF2+) counterparts, whereupon the

49 the EGFR-mutated NCI-H1975 and HCC827 cells, TTF-1 desensitized these cells to cisplatin; concomitant

50 tacts, both involving the positively charged TTF group of one monomer and the negatively charged cent

51 On charging, TTF is oxidized to TTF(+) at the cathode surface; TTF(+)

52 e of the resulting supramolecular complexes (TTF-C4P + fullerene + halide anion + tetraalkylammonium

53 d SUMOylated BEND3 stabilizes NoRC component TTF-1-interacting protein 5 via association with ubiquit

54 zed these cells to cisplatin; concomitantly, TTF-1 conferred an increase in p-AKT.

55 e does topology play in catenanes containing TTF units?

56 Conversely, TTF-1 counters epithelial to mesenchymal transition in c

57 patient characteristics associated with CR, TTF, and OS establishes a baseline to compare and incorp

58 that the ability of pioglitazone to decrease TTF-1 expression contributes to its pro-adipogenic actio

59 Defining TTF as either starting a new treatment or death, estimat

60 If these newly designed TTF- and PMDI-based crystals with high polarizations are

61 ssociation of TTF+* to form the diamagnetic [TTF+,TTF+] dication and to also undergo the equally rapi

62 states of the two constitutionally different TTF units in the [2]catenane still experience long-range

63 formation between constitutionally different TTF units.

64 d increases markers of lung differentiation (TTF-1 and Mucin 5B).

65 encapsulates the better pi-electron-donating TTF station.

66 ilicene with either a strong electron donor (TTF) or a strong electron acceptor (TCNQ) and demonstrat

67 Dithiophene-tetrathiafulvalene (DT-TTF) derivatives can be readily prepared through trialky

68 f TTF-1(+) lung cancer cells (designated EDM-TTF-1(+)) displayed an anti-angiogenic activity in the e

69 stimulating factor (GM-CSF) level in the EDM-TTF-1(+) conferred the antiangiogenic activities.

70 ecular slabs of (EDT-TTF-CONH(2))(2)(+) (EDT-TTF = ethylenedithiotetrathiafulvalene) and anionic [BAB

71 yl-ethylenedithio-tetrathiafulvalene (DM-EDT-TTF) 1 donors are synthesized by cross coupling followed

72 nstrate the emergence of a QSL state in [EDT-TTF-CONH(2)](2) (+)[[Formula: see text]] (EDT-BCO), wher

73 th highly conducting molecular slabs of (EDT-TTF-CONH(2))(2)(+) (EDT-TTF = ethylenedithiotetrathiaful

74 ithin the highly conducting crystals of (EDT-TTF-CONH(2))(2)(+)[BABCO(-)] are essentially "braked" at

75 r 1 (TTF-1) to an upstream response element (TTF-1-binding element [TBE]).

76 rahigh local concentration for the encircled TTF units to form stable dimers associated with their di

77 II cells decreased DNA binding of endogenous TTF-1, blocked cAMP stimulation of surfactant proteins,

78 hermore, in cells that lack TTF-1, exogenous TTF-1 expression dampened the inhibitory effect of TGF-b

79 lymerase I transcription termination factor (TTF-I), it has been speculated that the p19Arf-Mdm2-p53

80 ound that the temporal transcription factor (TTF) Eyeless/Pax6 regulates the development of two recur

81 of lung developmental transcription factors (TTF-1, NKX2-8, and PAX9) that we recently discovered as

82 ly, prediction of time to treatment failure (TTF) and overall survival (OS) in mantle cell lymphoma (

83 AGC with a better time-to treatment failure (TTF) compared to ECX, ECX arm (ECX followed by FOLFIRI)

84 ent in the median time to treatment failure (TTF) compared with that reported for six cycles of R-CHO

85 ary criterion was time-to-treatment failure (TTF) of the first-line therapy.

86 Time-to-treatment failure (TTF) to EGFR TKI in patients identified as MET-high and

87 se incidence, and time to treatment failure (TTF) were examined by race.

88 se duration (RD), time to treatment failure (TTF), clinical benefit rate (CBR), and safety.

89 primary end point-time to treatment failure (TTF), which included patients without a response after f

90 survival (OS) and time to treatment failure (TTF).

91 survival (OS) and time to treatment failure (TTF).

92 of the study was time to treatment failure (TTF).

93 urvival (OS), and time to treatment failure (TTF).

94 Time to treatment failure (TTF; defined as discontinuation, progressive disease, de

95 erexpression in murine tail tip fibroblasts (TTFs) and cardiac fibroblasts (CFs) from multiple lines

96 iPSCs from adult mouse tail-tip fibroblasts (TTFs) using retroviral vectors or virus-free piggyBac tr

97 Finally, TTF-1 knockdown conferred human lung cancer cells resist

98 Transit time flow (TTF) probes may be useful for predicting long-term graft

99 index (hazard ratio [HR], 2.0; P = .0054 for TTF, and HR, 2.1; P = .068 for OS).

100 08) for TTP, 0.99 (95% CI, 0.92 to 1.06) for TTF, and 0.98 (95% CI, 0.87 to 1.11) for OS.

101 MIPI was similarly prognostic for TTF.

102 ated in order to study their ability to form TTF radical dimers.

103 one van der Waals interaction when the four TTF groups host a 1+ charge, and (4) the net stabilizing

104 = 7.6E-08); a block of 23 SNPs in XPA/FOXE1 (TTF-2) associated with serum TSH (p = 5.5E-08 to 1.0E-09

105 er studies (MTNR1B, ZNF259/APOA5, XPA/FOXE1 (TTF-2), DARC, CCR3, ABO); 2) localized novel genes in pl

106 Use of the Tip Transfer Function (TTF) is a key concept in making Magnetic Force Microscop

107 The thyroid transcription factor 1 gene (TTF-1 or NKX2-1) is essential to lung development; howev

108 c absorption studies suggest that they have [TTF](l+)...[TTF](m+) interactions that are preserved at

109 irectly regulated by TTF-1 and clarifies how TTF-1 controls HMGA2 expression.

110 t indicates that locking the redox-active IF-TTF units in close proximity promotes intramolecular mix

111 readily obtainable dibromo-functionalized IF-TTF building block using palladium-catalyzed cross-coupl

112 denofluorene-extended tetrathiafulvalene (IF-TTF) unit were synthesized in a stepwise protocol.

113 a significantly lower potential when the IF-TTF unit is incorporated into a dimer, compared to a mon

114 on the development of a new unsymmetrical IF-TTF building block by a combination of phosphite-mediate

115 enofluorene-extended tetrathiafulvalenes (IF-TTFs) with thioacetate end groups was prepared from a re

116 No significant differences in TTF or overall response to therapy were seen.

117 treatment, but experience no differences in TTF or overall response to therapy.

118 that the induction of GMT overexpression in TTFs and CFs is inefficient at inducing molecular and el

119 Including TTF in the assessment of risk for glaucoma blindness did

120 miR-200 antagonists inhibited TTF-1 and surfactant proteins and up-regulated TGF-beta2

121 in all cases, has three short interfragment [TTF](l+)...[TTF](m+) interactions.

122 Intraoperative TTF probe data may be helpful in predicting long-term pa

123 studies suggest that they have [TTF](l+)...[TTF](m+) interactions that are preserved at room tempera

124 , has three short interfragment [TTF](l+)...[TTF](m+) interactions.

125 Furthermore, in cells that lack TTF-1, exogenous TTF-1 expression dampened the inhibitor

126 t treatment end point correlated with longer TTF and OS.

127 We measured TTF and/or PI in 2738 grafts, and 1-year patency was det

128 Mechanistically, TTF-1 induced a reduction in p-AKT (S473), which in turn

129 Median TTF was 12.2 months (95% CI, 5.7 to 22.6 months) versus

130 Median TTF was similar at 9.24 months (ATA + TOR) versus 10.44

131 g a new treatment or death, estimated median TTF was 5.7 months.

132 fter a median follow-up of 31 months, median TTF was significantly longer with FOLFIRI than with ECX

133 a median follow-up of 72 months, the median TTF was 34.2 months.

134 ation of a maximum of two long, multicenter [TTF](*+)...[TTF](*+) bonds when all TTF groups host a 1+

135 the VEGF promoter element contains multiple TTF-1-responsive sequences.

136 ive electron-rich recognition units, namely, TTF and DNP, was investigated by electrochemistry and sp

137 est S...S interaction defined by neighboring TTF cores, which inversely correlates with the ionic rad

138 f the TTF*+ or TTF2+ back to being a neutral TTF.

139 The similar oxidation potentials of neutral TTF and the molecular precursor [HNEt(3) ](2) [M(pdms)(2

140 g that involves the oxidation of the neutral TTF ring system to either its radical cationic (TTF*+) o

141 the oxyphenylene station back to the neutral TTF station was slowed considerably by the longer linker

142 ield-switched low-symmetry structures of new TTF- and PMDI-based crystals.

143 study highlights the enigmatic activities of TTF-1 in lung cancer, and calls for future research to o

144 w miRNAs influence the oncogenic activity of TTF-1 and the role of TTF-1 in cholesterol metabolism.

145 sent a numerical study of several aspects of TTF reconstruction using multilayer samples with perpend

146 stablish the spontaneous self-association of TTF+* to form the diamagnetic [TTF+,TTF+] dication and t

147 occludin, which represents another avenue of TTF-1-mediated metastasis suppression.

148 to the metastasis-critical signaling axis of TTF-1 to HMGA2, we used both reverse and forward strateg

149 The electrocatalytic behavior of TTF-TCNQ-ionic liquid gels toward oxidation of thiocholi

150 dent and is mediated by increased binding of TTF-1/Nkx2.1 and NF-kappaB to a critical response elemen

151 the cohort of patients with coactivation of TTF-1 and NKX2-8 pathways appears to be resistant to sta

152 or prognosis associated with coactivation of TTF-1 and NKX2-8 was validated in 2 other independent cl

153 Surprisingly, the EDM of TTF-1(+) lung cancer cells (designated EDM-TTF-1(+)) dis

154 Examples of TTF estimation are shown on both 2D and 3D experimental

155 In human lung cancer, the expression of TTF-1 and GM-CSF exhibits a statistically significant an

156 ocked [2]catenanes controls the formation of TTF radical dimers within their structural frameworks, i

157 The frequency of TTF increased with stage of glaucomatous loss: 28.3% in

158 GA2) mediates the antimetastatic function of TTF-1.

159 The relative influence of TTF on the risk of blindness in the 2 matched groups was

160 ion occurred through a direct interaction of TTF-1 with the OCLN and CLDN1 promoters.

161 Finally, the conditioned media of TTF-1-transefected cells sensitized TTF-1(-) cells to ci

162 gh TP53 expression was a strong predictor of TTF and inferior OS compared with low TP53 expression in

163 was associated with increased recruitment of TTF-1, NF-kappaB, PCAF, and CBP, as well as enhanced ace

164 Reversible oxidation and reduction of TTF moieties changes the linker flexibility, which in tu

165 Li2O2, which results in the regeneration of TTF.

166 -33a) is under direct positive regulation of TTF-1.

167 be under a direct and positive regulation of TTF-1.

168 oncogenic activity of TTF-1 and the role of TTF-1 in cholesterol metabolism.

169 h has been conducted to investigate roles of TTF-1 in lung cancer biology.

170 bypass grafting (CABG); however, studies of TTF probe use are limited.

171 Use of TTF probes to assess graft flow and pulsatility index (P

172 Through both gain- and loss-of-TTF-1 expression strategies, we show that TTF-1 positive

173 traoperative revision were compared based on TTF measurements (<20 [low flow] vs >/=20 mL/min [normal

174 risation parameter selection method based on TTF width and verify this approach via numerical experim

175 ed for detection of carbamate drugs based on TTF-TCNQ-ionic liquid gel thiocholine sensor.

176 nd that such treatment does not affect OS or TTF.

177 CBPQT(4+) ring away from the singly oxidized TTF(+) unit by overcoming one of the thiomethyl (SMe) sp

178 has obvious correspondence with the oxidized TTF(+) distributions in the electric fields of the charg

179 te) to a tetrathiafulvalene calix[4]pyrrole (TTF-C4P) donor enforces a host conformation that favors

180 C70) by tetrathiafulvalene-calix[4]pyrrole (TTF-C4P) receptors and the nature of the resulting supra

181 The unifying theory regarding TTF-1 is that it exhibits both pro-oncogenic and anti-me

182 Surprisingly, pioglitazone repressed TTF-1 expression in PPFP-expressing thyrocytes.

183 Suboptimal response (TTF, 1.0 to 6.4 months) to EGFR TKI was observed in pati

184 zed molecular structure and an electron-rich TTF moiety.

185 n potential of the small, structurally rigid TTF-AB macrocycle is found to depend on the conformation

186 recommendations on best practices for robust TTF estimation, including the choice of windowing functi

187 onverted to the unusual cation-radical salt, TTF+* CB- (where CB- is the non-coordinating closo-dodec

188 media of TTF-1-transefected cells sensitized TTF-1(-) cells to cisplatin, implicating that the TTF-1-

189 The separate TTF units in the two {1+1} macrocycles (each containing

190 (>50% positive lymphoma cells) had a shorter TTF and poor OS independent of both MIPI score and Ki-67

191 g adenocarcinomas, we observed that silenced TTF-1 expression down-regulated occludin, which we suppo

192 al (3D) conductive single-ion magnet (SIM), (TTF)(2) [Co(pdms)(2) ] (TTF=tetrathiafulvalene and H(2)

193 gists to identify lung adenocarcinomas since TTF-1 is expressed in 60 ~ 70% of lung ADs.

194 Centimeter-sized segregated stacking TTF-C60 single crystals are crystallized by a mass-trans

195 s of the P-C60 dyad unit and the two-station TTF-DNP-based [2]rotaxane separately, using conventional

196 s oxidized to TTF(+) at the cathode surface; TTF(+) in turn oxidizes the solid Li2O2, which results i

197 functions as a donor, whereas in our system TTF is both a donor and an accepter because of the simil

198 Tetrathiafulvalene (TTF) as the prototypical electron donor for solid-state

199 )) mobile ring between a tetrathiafulvalene (TTF) station and an oxyphenylene station, were synthesiz

200 y that consists of (i) a tetrathiafulvalene (TTF) unit as an efficient pi-electron-donor station, (ii

201 angement of redox-active tetrathiafulvalene (TTF) arms, which serve as the guest binding centers.

202 ontaining a redox-active tetrathiafulvalene (TTF) ring system within its rod section has been synthes

203 eneethynylene) (OPE) and tetrathiafulvalene (TTF) scaffolds, end-capped with acetyl-protected thiolat

204 oxynaphthalene (DNP) and tetrathiafulvalene (TTF) units along with a 4,4'-bipyridinium (BIPY(*+)) rad

205 thylferrocene (DMFc) and tetrathiafulvalene (TTF).

206 electron donors such as tetrathiafulvalene (TTF).

207 Macrocyclization between tetrathiafulvalene (TTF) dithiolates and bis-bromomethylazobenzenes/bis-brom

208 g a dumbbell, containing tetrathiafulvalene (TTF) and 1,5-dioxynaphthalene (DNP) recognition units wh

209 active stalks containing tetrathiafulvalene (TTF) units, (b) [2]pseudorotaxanes formed between these

210 ilized, redox-controlled tetrathiafulvalene (TTF) dimers, enabling their spectrophotometric and struc

211 ransfer complexes, i.e., tetrathiafulvalene (TTF)- and pyromellitic diimide (PMDI)-based crystals, th

212 ce of the redox mediator tetrathiafulvalene (TTF) in 1.0 m LiClO4 dissolved dimethyl sulfoxide electr

213 ion of a redox mediator, tetrathiafulvalene (TTF), enables recharging at rates that are impossible fo

214 ) and the guest molecule tetrathiafulvalene (TTF).

215 electronic properties of tetrathiafulvalene (TTF) can be tuned by attaching electron-donating or elec

216 present the evolution of tetrathiafulvalene (TTF) fused D-A systems and their potential applications

217 uccessful replacement of tetrathiafulvalene (TTF) with a nickel glyoximate core in a family of isostr

218 pect to the oxidation of tetrathiafulvalene (TTF), where the TTF(0/*+) process is used as a reversibl

219 tems based on the parent tetrathiafulvalene (TTF).

220 nical bonding stabilizes tetrathiafulvalene (TTF) radical dimers, the question arises: what role does

221 via a vinylene-bridge to tetrathiafulvalene (TTF) units, is presented.

222 ient ring and either two tetrathiafulvalene (TTF) and 1,5-dioxynaphthalene (DNP) containing macrocycl

223 sopropylacrylamide) with tetrathiafulvalene (TTF) end groups complexed with CBPQT(4+) induced positiv

224 lectronic properties to tetrathiafulvalenes (TTFs).

225 Here, we demonstrate that TTF-1 transactivated the expression of the epithelial ti

226 atin immunoprecipitation, we determined that TTF-1 binds to the promoter of SREBF2, the host gene of

227 This study provides direct evidence that TTF truly plays a role in promoting the decomposition of

228 n summary, this study provides evidence that TTF-1 may reprogram lung cancer secreted proteome into a

229 Our data indicate that TTF-1 interacts with PPFP to inhibit the pro-adipogenic

230 of-TTF-1 expression strategies, we show that TTF-1 positively regulates vascular endothelial growth f

231 kdown and overexpression studies showed that TTF-1 inhibits PPFP target gene expression and impairs a

232 Our study shows that TTF-1 sensitizes the KRAS-mutated A549 and NCI-H460 lung

233 Collectively, these data suggest that TTF-1 transcriptionally regulates occludin, which repres

234 of HMGA2 without the 3'-UTR, suggesting that TTF-1 keeps the prometastasis gene HMGA2 in check via up

235 ulating cholesterol metabolism suggests that TTF-1 may be a modulator of cholesterol homeostasis in t

236 The TTF-1-dependent upregulation of VEGF was moderately sens

237 The TTF-1-induced VEGF upregulation occurs in both compartme

238 The TTF-derived iPSC clones exhibited similar morphology and

239 The TTF-TCNQ-ionic/ionic liquid gel was characterized by FT-

240 s presence of three short contacts among the TTF groups in the optimum geometry of the clip2(n+) dime

241 tive charge is equally distributed among the TTF groups, while a 1- au charge is located in the centr

242 ween the SIM donor [M(pdms)(2) ](n-) and the TTF(.+) acceptor, as well as an intradonor CT from the p

243 n movements of the alpha-CD ring between the TTF and newly formed triazole ring systems have been elu

244 ansfer (CT) occurring in a dimer between the TTF residues and are rationalized based on a theoretical

245 The interactions between the TTF-C4P receptors and the fullerene guests are highly in

246 potential is applied, the ring encircles the TTF unit and displays a green color.

247 value of 0.55 cm s(-1) was obtained for the TTF(*+/2+) process at a glassy carbon electrode and 2.7

248 s of thousands of packing structures for the TTF- and PMDI-based crystals are first generated based o

249 more effectively than the BIQ2+ guest in the TTF-C4P cavity, leads to back electron transfer, restori

250 e scaffolds and the electronic nature of the TTF arms: the highest binding efficiency is shown by rec

251 ase of the [2]catenane, the formation of the TTF hetero radical dimer is prevented sterically by the

252 show that the out-of-plane distortion of the TTF moiety in this macrocycle is responsible for the var

253 3]catenanes facilitates the formation of the TTF radical dimers under redox control, allowing an inve

254 h a butadiyne group, the distribution of the TTF radical-cation dimer can be changed from 60% to 100%

255 as also been shown that the stability of the TTF radical-cation dimers can be tuned by varying the se

256 hifts (i) in the oxidation potentials of the TTF unit in (a)-(c) and (ii) the reduction potentials of

257 The oxidation process of the TTF unit is dramatically hampered in the rotaxane, there

258 Upon oxidation of the TTF unit, the CBPQT(4+) ring moves to the DNP unit, prod

259 chi affects the oxidation potentials of the TTF units to the extent that switching can be subjected

260 ment of the quasi-reversible kinetics of the TTF(*+/2+) process.

261 rotaxane can be reversed on reduction of the TTF*+ or TTF2+ back to being a neutral TTF.

262 Coactivation of the TTF-1 and NKX2-8 pathways identified a cluster of patien

263 ancer cell lines showing coactivation of the TTF-1 and NKX2-8 pathways were shown to exhibit resistan

264 ther increase the secreted VEGF level of the TTF-1(+) lung cancer cells.

265 Subsequent cooling led to reformation of the TTF-based host-guest complexes in solution and contracti

266 salts serves to modulate the strength of the TTF-C4P-fullerene host-guest binding interactions and, i

267 e 1,3-alternate to the cone conformer of the TTF-C4Ps, thus acting as positive heterotropic allosteri

268 molecular crystals are designed based on the TTF and PMDI motifs and an extensive polymorph search.

269 t the alpha-CD ring prefers to reside on the TTF rather than on the triazole ring system by at least

270 It is found that the TTF addition does not obviously affect the discharge rea

271 (-) cells to cisplatin, implicating that the TTF-1-driven chemosensitization activity may be dually p

272 ation of tetrathiafulvalene (TTF), where the TTF(0/*+) process is used as a reversible internal refer

273 understanding of the interactions within the TTF radical dimers.

274 ToRC comprises ISWI, Toutatis/TIP5 (TTF-I-interacting protein 5), and the transcriptional co

275 eyes were divided into 2 groups according to TTF in the first glaucomatous visual field: (1) eyes wit

276 On charging, TTF is oxidized to TTF(+) at the cathode surface; TTF(+) in turn oxidizes t

277 electronic affinity replaces the traditional TTF-bipyridinium interaction, which is over-ridden by st

278 arent donor to form the mixed-valence [TTF+*,TTF] cation-radical.

279 unique structure of the mixed-valence [TTF+*,TTF] dyad on (a) the electron-transfer mechanism for sel

280 ation of TTF+* to form the diamagnetic [TTF+,TTF+] dication and to also undergo the equally rapid cro

281 aximum of two long, multicenter [TTF](*+)...[TTF](*+) bonds when all TTF groups host a 1+ au of charg

282 ining two 1,5-dioxynaphthalene (DNP) and two TTF units) that is topologically isomeric with the doubl

283 on-rich macrocyclic polyether containing two TTF units of different constitutions, namely 4,4'-bis(hy

284 hthalene (DNP) containing macrocycles or two TTF-butadiyne-containing macrocycles as the pi-electron

285 8, we studied a subset of 1607 who underwent TTF probe analysis of 1 or more grafts during surgery.

286 Usually TTF functions as a donor, whereas in our system TTF is b

287 is over-ridden by stabilizing mixed-valence (TTF)2*+ and radical-cation (TTF*+)2 states inside the 'm

288 its parent donor to form the mixed-valence [TTF+*,TTF] cation-radical.

289 f the unique structure of the mixed-valence [TTF+*,TTF] dyad on (a) the electron-transfer mechanism f

290 67, SOX11 expression was not associated with TTF, but patients with low SOX11 expression had shorter

291 ation of favorable prognosis associated with TTF-1(+) lung adenocarcinomas.

292 there were no differences between eyes with TTF and eyes without TTF after adjusting for disparities

293 variate analysis demonstrated that eyes with TTF at presentation compared with eyes without TTF becam

294 rst glaucomatous visual field: (1) eyes with TTF, defined as visual field loss (VFL) including >/=1 o

295 timally manage chemotherapy of patients with TTF-1(+) lung ADs.

296 ences between eyes with TTF and eyes without TTF after adjusting for disparities in disease severity

297 F at presentation compared with eyes without TTF became blind more often (56/182 [30.8%] vs. 22/127 [

298 -2 or 30-2 Humphrey fields; (2) eyes without TTF, defined as VFL only outside the 4 innermost points.

299 FM were superior to R-CVP in terms of 3-year TTF and PFS.

300 fter a median follow-up of 34 months, 3-year TTFs were 46%, 62%, and 59% for the respective treatment