ライフサイエンスコーパス: TUNEL staining

1 ytochrome C release, caspase 3 activity, and TUNEL staining).

2 alter macrophages bearing a marker of death (TUNEL staining).

3 rase-mediated dUTP-biotin nick end-labeling (TUNEL) staining).

4 improved histological changes and decreased TUNEL staining.

5 tivation, lactate dehydrogenase release, and TUNEL staining.

6 tern blotting, and apoptosis was analyzed by TUNEL staining.

7 for quantification of neovascularization and TUNEL staining.

8 of caspases 3/7, and increased annexin V and TUNEL staining.

9 rther confirmed by histological analysis and TUNEL staining.

10 ivity, reduced cell viability, and increased TUNEL staining.

11 ion, and with minimal caspase activation and TUNEL staining.

12 s and increases in ALT and AST, and positive TUNEL staining.

13 e, despite reduced cell death as measured by TUNEL staining.

14 as indicated by both caspase-3 activity and TUNEL staining.

15 apoptosis was semiquantitatively analyzed by TUNEL staining.

16 expressing R116C mutant had a high level of TUNEL staining.

17 72 h that was supported by DNA analysis and TUNEL staining.

18 responded to a similar pattern of silver and TUNEL staining.

19 t LDH leakage, oligonucleosome formation and TUNEL staining.

20 cluding the formation of pyknotic nuclei and TUNEL staining.

21 ndicated by reduced caspase 3 activation and TUNEL staining.

22 duced dose-dependent apoptosis with positive TUNEL staining.

23 somic cleavage of DNA (laddering) as well as TUNEL staining.

24 th elevated caspase-3 activity and increased TUNEL staining.

25 WT mice via qPCR, WB analysis, H&E, IF, and TUNEL staining.

26 ed in tumor tissue in the absence of GLI1 by TUNEL staining.

27 tubular brush border and increased NGAL and TUNEL staining.

28 uring retinal developmental as determined by TUNEL staining.

29 orphologic analysis as well as annexin V and TUNEL staining.

30 sions, SMCs and ECs colocalized with IgE and TUNEL staining.

31 se of caspase 8 activation and photoreceptor TUNEL staining.

32 dU incorporation and activated caspase-3 and TUNEL staining.

33 ay, caspase 8 immunoblots, and photoreceptor TUNEL staining.

34 ermined by caspase-3 activation and positive TUNEL staining.

35 Apoptotic cell death was assessed by TUNEL staining.

36 Apoptosis was detected with TUNEL staining.

37 g pathways were assessed by Western blot and TUNEL staining.

38 mmunohistochemistry, immunofluorescence, and TUNEL staining.

39 ntly increased apoptotic T cells detected by TUNEL staining.

40 leotidyl transferase dUTP nick end labeling (TUNEL) staining.

41 idyl transferase-mediated nick end labeling (TUNEL) staining.

42 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining.

43 idine triphosphate-biotin nick end-labeling (TUNEL) staining].

44 ased after compared with before CPB/CA using TUNEL staining (1.55+/-0.66 versus 0.325+/-0.05%, respec

45 ) at equimolar concentrations as assessed by TUNEL staining [1 mcmol/L: NE (8+/-2%) approximately ISO

46 2,3,5-triphenyl-2H-tetrazolium chloride and TUNEL staining 24 h after stroke.

47 romodeoxyuridine incorporation and increased TUNEL staining accompanied these decreases.

48 tosis, including no caspase-3 activation, no TUNEL staining, activation of ERKs, and elevated spinal

49 Apoptosis was determined by TUNEL staining, active caspase-3 staining, and by activa

50 From Mason staining and TUNEL staining, aFGF-NP+UTMD group showed significant di

51 ue integrity were assessed via histology and TUNEL staining after 6 h of perfusion.

52 transferase-mediated dUTP nick end-labeling (TUNEL) staining after 24 h.

53 inal ganglion cells with fluorescent dye, or TUNEL staining) after up to a 1-year duration of diabete

54 Necrosis and TUNEL staining also increased twofold and sevenfold, res

55 TUNEL staining also revealed less brain apoptosis in tra

56 dUTP nick end labeling (TUNEL) staining also revealed on-going apoptosis specifi

57 TUNEL staining and a nucleosome release assay were used

58 from ischemia-induced apoptosis detected by TUNEL staining and an apoptotic-related DNA fragmentatio

59 Apoptosis was determined by TUNEL staining and annexin-V labeling of phosphatidylser

60 db/db showed markedly elevated apoptosis by TUNEL staining and caspase 3 levels compared with WT.

61 Apoptosis, as measured by TUNEL staining and caspase expression, was decreased in

62 24 h MCAO was associated with a decrease in TUNEL staining and caspase-3 activity in the control ani

63 inhibition is associated with an increase in TUNEL staining and caspase-3 cleavage and is blocked wit

64 TUNEL staining and caspase-3 cleavage revealed less apop

65 sion in Stat3(DeltaDelta) mice were similar, TUNEL staining and caspase-3 were increased in alveolar

66 ent and there is minimal caspase activation, TUNEL staining and cell death.

67 embryonic day 12.5 (E12.5) according to both TUNEL staining and cleaved caspase 3 immunofluorescence.

68 We show by TUNEL staining and confirm by TEM that apoptosis occurs

69 growth inhibition correlated with increased TUNEL staining and decreased Ki-67 expression in both PC

70 of this mechanism correlates with increased TUNEL staining and decreased ventricular mass and functi

71 Salt-induced PCD (TUNEL staining and DNA laddering) in primary roots of bo

72 Typical apoptotic features (TUNEL staining and DNA laddering) were seen in rat retin

73 Apoptosis was assayed by Hoechst 33258 and TUNEL staining and DNA laddering.

74 Cell death was evaluated with TUNEL staining and ethidium homodimer-1 (EthD) dyes.

75 MRL/+ mice were evaluated for apoptosis with TUNEL staining and Fas and Fas ligand expression with im

76 TUNEL staining and immunostaining for Muller and photore

77 death was observed in the spleen by means of TUNEL staining and in the blood by means of electron mic

78 red staining, was associated with increased TUNEL staining and increased immunopositivity for macrop

79 orn Gsalpha transgenic mice showed increased TUNEL staining and internucleosomal DNA fragmentation co

80 ns, limited segmental demyelination, lack of TUNEL staining and lack of accumulation of ubiquitinated

81 Apoptosis was assessed by TUNEL staining and measuring activity of caspases 3 and

82 nfirmed the lack of DNA damage/cell death by TUNEL staining and MTT assay.

83 Retinal cryosections were examined by TUNEL staining and outer nuclear layer thickness measure

84 Cardiomyocyte apoptosis was determined by TUNEL staining and PARP cleavage (immunoblotting of nucl

85 Interestingly, TUNEL staining and PCNA staining showed neither enhanced

86 TUNEL staining and proteolysis were significantly reduce

87 matolysis, as determined by a combination of TUNEL staining and pulse-field and agarose gel electroph

88 Apoptosis in the RPE was examined by TUNEL staining and quantified by cell-death-detection EL

89 osis, and neuronal cell death, as assayed by TUNEL staining and retinal thickness at 6 and 12 weeks a

90 in articular chondrocytes was identified by TUNEL staining and the immunostaining of cleaved caspase

91 Cell apoptosis was determined by TUNEL staining and the immunostaining of cleaved caspase

92 Brain tissue was subjected to TUNEL staining and TUNEL positive cells were quantified.

93 TUNEL stainings and time-lapse video recordings demonstr

94 erminal transferase d-UTP nick-end labeling (TUNEL) staining and agarose-gel electrophoresis of extra

95 cleotidyltransferase dUTP nick-end labeling (TUNEL) staining and caspase 3 activation.

96 ne 5'-triphosphate-biotin nick end-labeling (TUNEL) staining and DNA gel electrophoresis.

97 rase-mediated dUTP-biotin nick end-labeling (TUNEL) staining and DNA laddering.

98 e death by TdT-dUTP terminal nick-end label (TUNEL) staining and transmission electron microscopy, fo

99 apoptosis (TdT-dUTP terminal nick-end label [TUNEL] staining) and p53 protein expression (immunohisto

100 son Trichrome staining), and apoptosis (with TUNEL staining), and we performed transcriptome analysis

101 otential, Bcl2 to BAX expression, along with TUNEL staining, and Annexin V binding were examined in R

102 hours as shown by nuclear chromatin changes, TUNEL staining, and caspase 3 activation.

103 by histopathology, serum aminotransferases, TUNEL staining, and caspase activation.

104 onstrated by reduced caspase-3 activity, HSC-TUNEL staining, and DNA fragmentation.

105 and apoptosis was assessed by DNA laddering, TUNEL staining, and ELISA for histone-associated DNA fra

106 increased Annexin V-FITC staining, increased TUNEL staining, and increased cleaved caspase 3 protein.

107 Flow cytometry, TUNEL staining, and light microscopy demonstrated that C

108 e was evaluated by pathological examination, TUNEL staining, and liver/kidney function tests to asses

109 , as demonstrated by DNA electrophoresis and TUNEL staining, and significantly improved neurological

110 transferase-mediated dUTP nick-end labeling (TUNEL) staining, and blockade by a caspase inhibitor.

111 transferase-mediated dUTP nick end labeling (TUNEL) staining, and DNA laddering.

112 sed for TdT-dUTP terminal nick-end labeling (TUNEL) staining, and the number of nuclei containing fra

113 transferase-mediated dUTP nick end labeling (TUNEL) staining, and Western blot for cleaved caspases.

114 tosis and also determined the reliability of TUNEL staining as an indicator of apoptosis in keratinoc

115 transferase-mediated dUTP nick end labeling (TUNEL) staining as early as 6 hours postlesion.

116 Cell death ELISA and TUNEL staining assays were used to assess apoptosis.

117 Pretreatment with ATA virtually eliminated TUNEL staining at 4 days.

118 asts failed to activate capase-3 or increase TUNEL staining but instead exhibited autophagy, as demon

119 crease in the amount of apoptosis in tips by TUNEL staining, but diminished proliferation throughout

120 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining, but not in neurons.

121 umber of apoptotic myocytes as determined by TUNEL staining by 3.6- fold.

122 e results demonstrate that the diminution in TUNEL staining by alpha-MSH is through alpha-MSH mediati

123 ite-bearing neurons against the induction of TUNEL staining by high glucose.

124 n and a decrease in apoptosis as measured by TUNEL staining, caspase 3 activation, and DNA laddering

125 mediated dUTP-digoxigenin nick-end labeling (TUNEL) staining, caspase-3 activation, and myeloperoxida

126 The IEC TUNEL staining, caspases 3, 8, and 9, and p53 protein le

127 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining characteristic of apoptosis.

128 c cell death at a high frequency as shown by TUNEL staining, chromatin condensation, and the appearan

129 leotidyl transferase dUTP nick-end labeling (TUNEL) staining, circulating levels of alanine aminotran

130 0.25 mM H(2)O(2) for 1 hour showed increased TUNEL staining compared with nonstressed cells (17 +/- 1

131 nd incorporated more 5-bromodeoxyuridine and TUNEL staining compared with unstimulated controls.

132 MDA (P = 0.006), but not M30 CK18 levels or TUNEL staining, compared to subjects without stainable h

133 TUNEL staining confirmed a decrease in residual apoptoti

134 TUNEL staining confirmed that photoreceptor and bipolar

135 DNA fragmentation detected by TUNEL staining could be induced by staurosporine and Fas

136 TUNEL staining coupled with morphologic assessment was p

137 The number of apoptotic cells using TUNEL staining decreased by nearly 50% in NGF-cultured i

138 TUNEL staining demonstrated increased rates of apoptosis

139 TUNEL staining demonstrated significantly reduced bronch

140 ear-infrared imaging of caspase activity and TUNEL staining demonstrated that TRA-8 rapidly induced a

141 TUNEL staining demonstrated the presence of apoptotic ce

142 transferase-mediated dUTP nick end labeling (TUNEL) staining demonstrated a 4-fold increase in apopto

143 Histology and TUNEL staining did not indicate cell injury or death in

144 ng flow cytometric analysis of PI uptake and TUNEL staining, DNA electrophoresis, and electron micros

145 independent measures of apoptosis, including TUNEL staining, DNA laddering, and caspase-3 activity, a

146 transferase-mediated dUTP nick end labeling (TUNEL) staining, DNA fragmentation, caspase-3 activity,

147 TUNEL staining for apoptosis was performed on 8 paraform

148 detected by increased BrdU labeling, whereas TUNEL staining for apoptotic cells was unaffected.

149 TUNEL staining for DNA double-strand breaks confirmed th

150 sessed by both Cresyl violet staining and by TUNEL staining for DNA fragmentation.

151 transferase-mediated dUTP nick-end labeling (TUNEL) staining for intratumoral apoptosis.

152 mediated dUTP-digoxigenin nick end-labeling (TUNEL) staining, glial fibrillary acidic protein (GFAP)

153 TUNEL staining identified dying cells at P14 through P60

154 DNA fragmentation was evident on TUNEL staining in 10/15 subjects injected with hemolysat

155 pho-Akt (P-Akt) staining accompanied by weak TUNEL staining in Axl-positive tumors, suggesting an ant

156 Extensive cell death was also detected by TUNEL staining in focal areas around lesions.

157 Retinal thinning, TUNEL staining in ONL, 4-HNE-, and 4-HHE protein modific

158 We also observed DNA cleavage determined by TUNEL staining in TBBEC treated with LPS.

159 l ischemic lesion area and largely prevented TUNEL staining in the cortex.

160 TUNEL staining in the MPNc was very low and although it

161 nd a statistically significant difference in TUNEL staining in tumor tissue between mice treated with

162 leotidyl transferase dUTP nick end labeling (TUNEL) staining in situ.

163 idine triphosphate-biotin nick-end labeling (TUNEL) staining in tumor biopsies (n = 15).

164 leotidyl transferase dUTP nick-end labeling (TUNEL) staining in vascular cells within the neovascular

165 (i.p.) of METH (30 mg/kg) induces apoptosis (TUNEL staining) in approximately 25% of neurons in the s

166 optosis (decreased cell viability, increased TUNEL staining, increased expression of cleaved PARP, cl

167 Positive TUNEL staining, increases in caspase-2 and -3 cleavage,

168 TUNEL staining indicated that PS-341 treatment sensitize

169 cytes showed more cleaved caspase-3 and more TUNEL staining, indicating an anti-apoptotic function of

170 d insulin+ beta-cells with some positive for TUNEL staining, indicating apoptosis.

171 ximately 20% of satellite cells positive for TUNEL staining, indicating DNA damage associated with ap

172 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining, indicating that the gene 7 products do

173 Cerebellar granule cells demonstrated high TUNEL staining indicative of apoptosis.

174 mal cornified layers and increased epidermal TUNEL staining, indicative of premature keratinocyte pro

175 Total lung lavage protein concentration, TUNEL staining, lipid peroxidation, and wet-to-dry ratio

176 ages and granulocytes that were apoptotic by TUNEL staining occasionally appeared to display A1 throu

177 Maximal TUNEL staining occurred in the piriform cortex between 1

178 Intense TUNEL staining of apoptotic cells was seen earlier (1 da

179 ogradely labeled neurons and no evidence for TUNEL staining of axotomized cortical motoneurons.

180 inding and time course of apoptosis, whereas TUNEL staining of cardiac tissue sections identified spo

181 TUNEL staining of CNS tissue demonstrates the presence o

182 TUNEL staining of infected lung sections demonstrated in

183 S of P2X7R-/- mice early in the disease, and TUNEL staining of inflamed CNS tissues supported this re

184 TUNEL staining of lens epithelial cells in capsulotomy s

185 Blood levels of caspase 3 and TUNEL staining of liver were also reduced in dexamethaso

186 TUNEL staining of senescent HSCs showed approximately 21

187 TUNEL staining of the inner retina of the mouse was most

188 TUNEL staining of tissue sections showed significantly h

189 enzymatic assay of myocardial caspase 3 and TUNEL staining of tissue sections.

190 lls in the lamina propria and spleen by both TUNEL staining of tissues and dispersed spleen cell popu

191 cleotidyl transferase UTP nick-end labeling (TUNEL) staining of histologic sections in wild-type and

192 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining of intestinal sections revealed increase

193 transferase-mediated dUTP nick end-labeling (TUNEL) staining of lymphoid tissues (pharyngeal tonsil,

194 Apoptosis was assayed by TUNEL staining on preparations of corneal tissue section

195 ckness in paraffin-embedded sections, and by TUNEL staining on retinal cryosections.

196 ring ischemia alone, but it colocalized with TUNEL staining over the 3 time points of reperfusion.

197 ncreased bcl-2 associated X protein mRNA and TUNEL staining (p < 0.05).

198 tohepatitis (P < 0.05) and increased hepatic TUNEL staining (P = 0.02), as well as increased serum le

199 TUNEL staining peaked at 12 h, earlier than the diminish

200 TUNEL staining, real-time RT-PCR, immunostaining, and EL

201 TUNEL staining, real-time RT-PCR, polymorphonuclear neut

202 exhibited significantly more ferric iron and TUNEL staining relative to the control melanoma xenograf

203 nsferase mediated dUTP nick end labeling, or TUNEL, staining, respectively, and were compared with cl

204 TUNEL staining results corroborated this finding.

205 TUNEL-staining results in cultured stromal cells (kerato

206 Lineage tracing and TUNEL staining reveal that Nanos1-deficient PGCs fail to

207 TUNEL staining revealed a 6-fold increase in the number

208 Neither the DNA laddering assay nor TUNEL staining revealed an increase in apoptosis of PKCd

209 TUNEL staining revealed more apoptotic hypertrophic chon

210 Our data suggest that TUNEL staining should be evaluated with morphological ch

211 Moreover, TUNEL staining showed a high percentage of apoptotic cho

212 TUNEL staining showed cell death only around bubbles and

213 TUNEL staining showed little DNA breakage in neutrophils

214 TUNEL staining showed reduced apoptosis in the thymus of

215 TUNEL staining showed that ghrelin mitigated the signifi

216 TUNEL staining showed that the percent TUNEL positive nu

217 TdT-mediated nick end-label (TUNEL) staining showed apoptotic cells in regions expres

218 transferase-mediated dUTP nick end-labeling (TUNEL) staining suggested that cell death was due to apo

219 e in the rate of apoptosis, as determined by TUNEL staining, suggesting it plays a non-apoptotic role

220 ot result in detectable DNA strand breaks by TUNEL staining that are hallmarks of the classical apopt

221 TUNEL staining to detect apoptosis and immunohistochemic

222 resent study using propidium iodide and FITC-TUNEL staining to identify apoptotic cells, demonstrates

223 a high permeability to Ca(2+), we performed TUNEL staining to investigate the effects of receptor up

224 Instead, TUNEL staining, together with Fas, active caspase-3, and

225 Early in reperfusion, TUNEL staining was colocalized with endothelial cells fr

226 TUNEL staining was diminished after intravitreal TNF-alp

227 TUNEL staining was increased in Cx50D47A lenses, especia

228 TUNEL staining was marked, but ssDNA and cleaved caspase

229 cell death of transplanted RPE, as judged by TUNEL staining was observed rarely.

230 he corneas were processed for histology, and TUNEL staining was performed to assess whether blue-IRIS

231 TUNEL staining was performed to assess whether IRIS or N

232 TUNEL staining was performed to detect apoptosis.

233 Intense TUNEL staining was seen in BALB/c versus B6 cornea at 1

234 TUNEL staining was used for identification of apoptotic

235 TUNEL staining was used to analyze the cytotoxicity of T

236 ative stress was localized using 8-OHdG, and TUNEL staining was used to detect apoptosis.

237 TUNEL staining was used to quantitate the number of cell

238 TUNEL staining was variable.

239 idyl transferase-mediated nick-end labeling (TUNEL) staining was minimal in mice fed either diet befo

240 leotidyl transferase dUTP nick-end labeling (TUNEL) staining was performed to quantify apoptotic cell

241 TUNEL-staining was positive in the outer nuclear layer o

242 aspase 3 enzymatic activity and apoptosis by TUNEL staining were also increased after 12 weeks of dox

243 Immunoreactive p21/WAF1 and TUNEL staining were used as indicators of p53 activity f

244 Caspase-3 activity and TUNEL-staining were increased in KD hearts after ischemi

245 within 24 h and many cells were apoptotic by TUNEL staining, whereas virulent H37Rv exhibited minimal

246 enced by elevated caspase-3, -9 activity and TUNEL staining, which was completely blocked by Ucf-101,

247 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining with GFP.

248 TUNEL staining (with or without PMN depletion) and PMN i

249 There was TUNEL staining within choroidal neovascular lesions in e