ライフサイエンスコーパス: Th

1 Th cells integrate signals from their microenvironment t

2 Th cells show an impaired response to chemotactic stimul

3 Th ex vivo biodistribution of (89)Zr-BVDFO was also dete

4 Th subsets Th1 (CXCR3(+)), Th17 (CCR6(+)), and particula

5 V) multiple bonds compared to its 5f(0)6d(0) Th(IV) actinide congener.

6 association between a consensus T helper 1 (Th-1) immune response and favorable clinical outcomes ha

7 ts, Imiquimod triggered a strong T-helper-1 (Th-1)/cytotoxic immune response, characterized by the co

8 matory response, cytokine profiles and Th-1, Th-2 and Th-17 cells numbers in each mating type treated

9 to that of GPI-0100, potentiating mixed Th-1/Th-2 immune responses, which is different from those of

10 tion window of 0.8 Th with an offset of -0.2 Th, accurate ratios were measured across a 10-fold mixin

11 The reaction of (C5 Me5 )2 Th(CH3 )2 with the phosphonium salts [CH3 PPh3 ]X (X=Cl,

12 sphorus(V) intermediate, yielding (C5 Me5 )2 Th[kappa(2) -(C,C')-(CH2 )(CH2 )PPh2 ]Cl.

13 received with trace amounts of (227)Ac, (227)Th and (223)Ra, and the solution was used to evaluate th

14 was >99% (calculated based on (225)Ac, (227)Th, and (223)Ra).

15 a-emitting isotopes such as (225)Ac and (227)Th are incompatible with PET imaging.

16 They comprise the alpha-emitter (227)Th complexed to a 3,2-hydroxypyridinone chelator conjuga

17 )Ac(III) (with reduced (134)Ce(III)) or (227)Th(IV) (with oxidized (134)Ce(IV)).

18 Targeted (227)Th conjugates (TTCs) represent a new class of therapeuti

19 produced from a Thorium-229/Radium-225 ((229)Th/(225)Ra) generator, from high/low energy proton irrad

20 n (225)Ac generator from (225)Ra and/or (229)Th.

21 se from the ocean islands have moderate (230)Th and (226)Ra excesses, reflecting mantle melting in th

22 0 years and reconstruct high-resolution (230)Th-derived fluxes of (232)Th and excess barium, along wi

23 T inorganic ion exchange for Barium and (232)Th was determined to be 24.19 mg/mL for Barium and 5.05

24 powder contained 6 pg/g and 2 pg/g for (232)Th and (238)U, respectively.

25 gh-resolution (230)Th-derived fluxes of (232)Th and excess barium, along with redox-sensitive uranium

26 dose due to intake of (210)Po, (238)U, (232)Th and (40)K ranged from 280 and 800 muSv y(-1) for infa

27 to 233.3 Bq kg(-1) for (210)Po, (238)U, (232)Th and (40)K respectively, whereas they are below the de

28 3R and also increases the number of IL-3R(+) Th cells.

29 )H(2)(t)Bu(2)-2,6-Me-4)(4)] and [Li(THF)(4)][Th(OC(6)H(2)(t)Bu(2)-2,6-Me-4)(4)].

30 50 k for mass-to-charge ratio ( m/ z) of 526 Th and the transient length of 500 ms.

31 d a narrow precursor isolation window of 0.8 Th with an offset of -0.2 Th, accurate ratios were measu

32 Herein, we deliberately design a Th-metal-organic framework (MOF) for highly efficient se

33 -type structure with fcu topology built on a Th(6) secondary building unit and a tetrazole-based link

34 In this study, we report a Th-MOF artificial peroxidase, which can oxidize 3,3,5,5-

35 phoretic mobilities (mu(e)) of the actinides Th and U-Am in different oxidation states (prepared in 1

36 g the gene expression program of alternative Th fates.

37 NSiMe2 Bu(t) )3 , An=U, Pn=P, As, Sb, Bi; An=Th, Pn=P, As; Tren(TIPS) =N(CH2 CH2 NSiPr(i)3 )3 , An=U,

38 H2 CH2 NSiPr(i)3 )3 , An=U, Pn=P, As, Sb; An=Th, Pn=P, As, Sb].

39 sponse, cytokine profiles and Th-1, Th-2 and Th-17 cells numbers in each mating type treated mice sho

40 xchanger had high selectivity for Ba, Ag and Th.

41 mine signaling markers (e.g., Dat, Comt, and Th) between hBDNF(Val/Val) and hBDNF(Met/Met) mice, impl

42 Our findings suggest that the GP and Th in humans are part of a subcortical executive control

43 4(+) T cell marker expression, lifespan, and Th/regulatory T cell function.

44 congruent with those seen between newts and Th. sirtalis, including the same latitudinal gradient in

45 inflammatory response, cytokine profiles and Th-1, Th-2 and Th-17 cells numbers in each mating type t

46 ivation, IL-2 production, proliferation, and Th cell polarization.

47 uld separate (225)Ac from isotopes of Ra and Th, and the process represents an interesting one step s

48 ER had significantly higher T regulatory and Th cells, total macrophages, and programmed death ligand

49 Co, Fe, K, Mg, Mn, Mo, Na, Ni, Se, Sb, U and Th (p<0.05, all) among honeys.

50 A rapid new method for determining the U and Th mass concentrations in high radiopurity plastics is d

51 energies of formation (DeltaG(f)) for U- and Th-MOFs with 10- and 12-coordinated secondary building u

52 .1 kPa, n = 7) breast cancer xenografts, and Th-MYCN neuroblastomas (G (d) = 3.5 +/- 0.2 kPa, G (l) =

53 ssociate with less hydrated and more anionic Th-nitrato complexes.

54 nt of Rho-GTPase pathways in obese asthmatic Th cells, identifying them as a novel therapeutic target

55 At 100 kPa and 298 K Azole-Th-1 performs excellent separation of C(2)H(4) (purity >

56 The synthesized MOF Azole-Th-1 shows a UiO-66-type structure with fcu topology bui

57 As, Se, Sr, Mo, Cd, Sn, Sb, Ba, Hg, Pb, Bi, Th, and U) in green coffee samples and their infusions w

58 We found that human peripheral blood Th cells in resting state do not show surface expression

59 e were strong correlations both in Subcho.BP.Th and BV/TV between this scoring system and uCT (r = 0.

60 e spontaneous OA model showed that Subcho.BP.Th was significantly wider, angiogenesis was greater, an

61 ombination of Subcho.BP.thickness (Subcho.BP.Th) and angiogenesis, bone volume (BV/TV) and osteophyte

62 cilitated charge transfer, which make 2D CCP-Th a promising candidate for PEC water reduction.

63 AN (2D CCP-BD), the bithiophene-based 2D CCP-Th exhibits a wide light-harvesting range (up to 674 nm)

64 As a result, 2D CCP-Th presents a superb H(2) -evolution photocurrent densit

65 ThDAN) provides the 2D CCP-HATNThDAN (2D CCP-Th).

66 CD4 Th cells are organizers of the immune response, directin

67 ion of adaptive immunity by depletion of CD4 Th cells most likely contributes to loss of immune contr

68 Ox40 was highly expressed on several CD4 Th cell subsets in the spleen and kidney of diseased mic

69 CD4(+) Th cells are responsible for orchestrating diverse, path

70 that increased expression of Bcl-6 in CD4(+) Th cell populations correlated with enhanced enrichment

71 lished functions beyond their role in CD4(+) Th subsets.

72 ed the capacity of ILT3.Fc to inhibit CD4(+) Th cell proliferation and to induce the generation of CD

73 ollicular helper (Tfh) cell subset of CD4(+) Th cells promotes affinity maturation by B cells in germ

74 ical designation to the Th9 subset of CD4(+) Th cells, although it is also produced by additional cel

75 cription factor of the Th17 subset of CD4(+) Th cells, is a promising target for treating a host of a

76 are in contact with large numbers of CD4(+) Th cells.

77 h the ability to recruit BCG-specific CD4(+) Th cells may be a useful and broadly applicable approach

78 response against IgG2a(a) 3F7.A10 was CD4(+) Th cell-dependent, dominated by the IgG1 subclass, and I

79 Specific loss of PRMT5 in the CD4+ Th cell compartment suppressed Th17 differentiation and

80 hymic and peripheral homeostasis in the CD4+ Th cell life cycle and invariant NK (iNK) T cell develop

81 ore, studies using an in vitro CD11b(+) cell:Th cell coculture system revealed that CD11b(+)CD11c(+)

82 ouse, and detect whether the helper T cells (Th) and regulatory T cells (Treg) could affect osteoclas

83 le of a crystallographically characterizable Th(III) complex in the salts [K(THF)(5)(Et(2)O)][Th(OC(6

84 CMV-specific CD8+ (CMV-Tc), CD4+ (CMV-Th) T cell activity, and natural killer (NK) cell number

85 ] (6) and the known cyclometallated complex [Th{N(CH(2) CH(2) NSiPr(i) (3) )(2) (CH(2) CH(2) SiPr(i)

86 duces an unprecedented hexathorium complex [{Th(Tren(TIPS) )}(6) (mu-OC(2) P(3) )(2) (mu-OC(2) P(3) H

87 )CH(2) C(O)mu-P]}] (3) and the oxo complex [{Th(Tren(TIPS) )(mu-OCs)}(2) ] (7) were isolated.

88 ich can be converted to a rare oxo complex [{Th(Tren(TIPS) )(mu-ORb)}(2) ] (6) and the known cyclomet

89 A new thorium monoalkyl complex, Th(CH2SiMe3)(L3) (L = MeC(N(i)Pr)2) (2), undergoes inser

90 series of thorium chalcogenolate complexes, Th(ECH2SiMe3)(L3) (E = S, SS, Se, Te; 5-8).

91 vior, striatal BDNF levels, frontal cortical Th total percentage DNA methylation levels and serum cor

92 CCR6(+) and CXCR3(+) Th cells accumulate in the blood of aviremic HIV-1-infec

93 RVVC patients show no defective Th-dependent adaptive immune response upon Candida stimu

94 C subsets contribute uniquely in determining Th differentiation in pathogen-specific settings.

95 r RA patients on total Th cells or different Th cell subsets of healthy donors was analyzed in vitro.

96 CD4 T cells differentiate into distinct Th effector or regulatory subsets in response to signals

97 characterize the APC populations that drive Th responses in vivo.

98 genome-wide transcriptional response during Th differentiation to multiple subsets.

99 expression of the Maf/IL-10 axis in effector Th cells, Malat1 is a nonredundant regulator of mammalia

100 pared with that observed in non-TFH effector Th cells generated in response to influenza infection.

101 cells in noninoculated MEF, and the effector Th (CD44(+)) cell population increased at day 2 of NTHi

102 ulated relative to the corresponding element/Th ratio of the Upper Continental Crust) reveal maximum

103 ogenic memory of a discrete encephalitogenic Th subset.

104 on of viral vectors in adult male and female Th-Cre rats to transduce selectively RTN (Phox2b(+) /Nmb

105 as conditionally ablated using either floxed Th mice or viral-based CRISPR/Cas9.

106 Follicular Th (Tfh) cells orchestrate physiological germinal center

107 IFNgamma production, and inhibit follicular Th cell development.

108 n immunophenotype capable of Th1, follicular Th, and CTL functionalities, yet they are unable to be i

109 Adjusting for Th-cell subtype proportions discriminated loci where tra

110 mmatory cytokines, but is also essential for Th-mediated immunity, indicating complex effects of RA o

111 three-month water stability was reported for Th-containing frameworks herein, and the mechanism is al

112 the early actinide series is traversed from Th(IV) to U(IV) and Np(IV).

113 Assembled from [Th(48) Ni(6) ] nanocages, the first transition-metal (TM

114 cells, opposite to activated IFN-gamma(-/-) Th cells, partially reconstituted CF and HF in TCR-alpha

115 The ligands have Th-O-C(ipso) angles of 173.9(2) to 178.6(4) degrees , an

116 ligands we postulated to achieve heightened Th-1 immune response that would yield pronounced protect

117 LysM (Cre) :Ppard (fl/fl) mice to heightened Th responses.

118 ow accumulation of proinflammatory T helper (Th) 1 and Th17 cells resembling that of autoreactive imm

119 s, which expressed lower levels of T helper (Th) 1 and Th17 cytokines and higher levels of Th2 cytoki

120 The impact of T helper (Th) 1 versus Th2 immunity on intracellular infections is

121 ssociated in vivo with a decreased T helper (Th) 1/17 differentiation and Treg formation without impa

122 and lower frequency of pathogenic T helper (Th) 17 cells.

123 d food allergy, mainly by inducing T helper (Th) 2 immune responses and clinical trials with IL-33 in

124 ion and functional capacity of CD4 T helper (Th) and CD8 T cytotoxic (Tc) cell subsets in the rectal

125 ) were superior in inducing CD4(+) T helper (Th) cell polarization while simultaneously presenting an

126 Inter-individual differences in T helper (Th) cell responses affect susceptibility to infectious,

127 m, NKG2D-driven regulation of CD4+ T helper (Th) cell-mediated immunity remains unclear.

128 T helper (Th) cells are CD4(+) effector T cells that play a critic

129 ctional profile of auto-aggressive T helper (Th) cells during neuroinflammation and identified the si

130 The importance of CD4+ T helper (Th) cells is well appreciated in view of their essential

131 haracterized antigen-specific CD4+ T helper (Th) cells that developed in the context of myocardial in

132 namely effector choice among CD4+ T helper (Th) cells.

133 CD4(+) T helper (Th) differentiation is regulated by diverse inputs, incl

134 multiple functionally specialized T helper (Th) subsets.

135 can differentiate into pathogenic T helper (Th)-17 cells and germinal center (GC)-promoting T follic

136 7, a proinflammatory cytokine, and T helper (Th)17 cells are associated with chronic autoimmune disea

137 Atopic dermatitis (AD) is a T helper (Th)2-biased disease with elevated expression of Th2 cyto

138 evels of interleukin 23 (IL23) and T-helper (Th) 17 cell pathway molecules are increased in inflamed

139 in humoral, type I interferon, and T-helper (Th) 17 responses were associated with susceptibility to

140 unosuppression, and by a subset of T-helper (Th) 17-cells, where it limits pathogenicity.

141 T-helper (Th) cell differentiation drives specialized gene program

142 T-cell population was dominated by T-helper (Th) cells in noninoculated MEF, and the effector Th (CD4

143 his bone loss is associated with a T-helper (Th)1 and Th17-pattern of immune response.

144 d Pb, LREE then La-Ce-Nd-Sm, Lu(Yb), and Hf, Th, and U, respectively) along with an additional, in-ho

145 llation, we were able to achieve the highest Th wt % in mono- and biactinide frameworks with minimal

146 t the expression of IL-3R on activated human Th cells is modulated by IL-4, and IL-3 regulates the ef

147 M6A and KDM6B as central regulators of human Th subsets.

148 the regulation of IL-3R expression on human Th cells and also examined the role of IL-3 in effector

149 -sensing C-fibers, and tyrosine hydroxylase (Th), specific to low-threshold mechanoreceptive C-fibers

150 striatal expression of tyrosine hydroxylase (Th)], glucocorticoid receptor (GR) and plasma corticoste

151 ata and the redox-stable analogues (Eu(III), Th(IV), Np(V), U(VI)) that have also been investigated.

152 bolites sensed by both intestinal and immune Th cells.

153 In Th cell subsets, Th2 cells produce considerable amounts

154 TCR interaction with p:MHCII plays a role in Th differentiation by mechanisms that are not completely

155 a major function of RA-RARalpha signaling in Th differentiation, arguing for a role for RA in interle

156 n important role in preventing inappropriate Th cell responses under normal conditions.

157 this pathway in the regulation of individual Th cell differentiation programs.

158 ly affects the differentiation of individual Th cell subsets.

159 e plasticity and heterogeneity of individual Th cells, the tunable mixtures of effector types that ca

160 We profiled genome-wide allergen-induced Th-cell responses prospectively during 24 months subcuta

161 ates progressive integration of mite-induced Th cell-associated Th2-, FOXP3/IL2-, inflammation- and f

162 Prior to immunotherapy, mite-induced Th-cell response networks involved multiple discrete co-

163 s mucosal T cell activation and inflammatory Th cells.

164 suggest that TCR affinity does not influence Th cell differentiation by biasing T cell interactions w

165 r the Ce=N bond compared with the more ionic Th=N bond.

166 blended with the non-fullerene acceptor ITIC-Th and analyze the effects of substituent dimensions on

167 In addition to the known Th and U complexes, our calculations include complexes o

168 l-Th biochemically modulates various anti-neoplastic agent

169 l-Th enhances the umami taste but its use is limited due t

170 effort to condense the recent research on l-Th highlighting its biological resource, plausible role

171 aled a role for PPAR-delta in DC in limiting Th cell priming during EAE.

172 with some REEs (i.e. Sc, La, Ce, Pr, Nd, Lu, Th).

173 erentiation into CD4(+) helper T lymphocyte (Th)17 cell phenotypes.

174 These results indicate that many Th cell subsets can promote plasmablast formation by pro

175 ule PRMT5 inhibitors severely blunted memory Th expansion, with preferential suppression of Th1 cells

176 In contrast, memory Th cells were primarily directed against just a few immu

177 ast, relative frequencies of CXCR5(-) memory Th cells as well as regulatory T and B cells were increa

178 imal proliferation of mouse and human memory Th cells.

179 Ab responses in BALB/c mice and a more mixed Th response.

180 ilar to that of GPI-0100, potentiating mixed Th-1/Th-2 immune responses, which is different from thos

181 hanisms by which noninflammatory SF modulate Th cell responses and to determine the immunosuppressive

182 role and mechanisms by which PRMT5 modulates Th cell polarization and autoimmune disease have not yet

183 BATF is required for development of multiple Th subsets but functions in a lineage-specific manner.

184 with asthma had more memory and fewer naive Th cells than normal-weight children with asthma.

185 ay 114 had additional abnormalities in naive Th, naive regulatory T (Treg) cell populations, and cyto

186 When naive Th cells were activated in the presence of various cytok

187 map the vascular phenotype in neuroblastoma Th-MYCN transgenic mice treated with the vascular endoth

188 2R expression longer and expressed two novel Th cell differentiation regulators, Eef1e1 and Gbp2, to

189 II) complex in the salts [K(THF)(5)(Et(2)O)][Th(OC(6)H(2)(t)Bu(2)-2,6-Me-4)(4)] and [Li(THF)(4)][Th(O

190 are coplanar to within 0.05 angstrom with O-Th-O angles of 89.27(8) to 92.02(8) degrees between cis

191 s by IL-25 promoted proximal accumulation of Th cells, and stimulation of Th cells by IL-25 locally p

192 -) mice that showed decreased acquisition of Th cells in Coccidioides-infected lungs compared with va

193 ydrothermal fluids, and thus the behavior of Th in ore-forming systems and the nuclear fuel cycle nee

194 The catalytic behavior of Th-MOF tracked Michaelis-Menten equation and the affinit

195 thermal deposits with high concentrations of Th challenges the Th immobility paradigm and strongly su

196 ytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but

197 this study, we compared the distribution of Th and Tc cell subsets between blood and RM compartments

198 we observed similar tissue distributions of Th and Tc cell subsets, although Tc17 cell frequencies i

199 in mDA neurons resulted in downregulation of Th and Dat, as well as in severe motor deficits.

200 n factor predicted to regulate expression of Th and Dat, genes critical for dopamine synthesis and re

201 n obese children with asthma, independent of Th-cell subtype proportions, were enriched in Rho-GTPase

202 (BDNF) and total percent DNA methylation of Th and Bdnf genes in the frontal cortex and hippocampus.

203 pregulation of Th-1 chemokines, migration of Th-1 and cytotoxic T cells into the tumor, and activatio

204 models grossly underestimate the mobility of Th in hydrothermal fluids, and thus the behavior of Th i

205 ic cytokine signaling into a simple model of Th differentiation comprehensively explains divergent ob

206 activating signals influence the outcome of Th cell differentiation via differential regulation of m

207 ppaB, might determine the precise outcome of Th-cell differentiation upon encounter with cDC1s.

208 rait covariation across the shared ranges of Th. couchii and newt prey.

209 Reduction of Th(OC(6)H(2)(t)Bu(2)-2,6-Me-4)(4) using either KC(8) or

210 accumulation of Th cells, and stimulation of Th cells by IL-25 locally promoted IL-13 and IL-9 produc

211 We postulate that the suppression of Th cell growth by SF through tryptophan catabolism may p

212 acterized by the coordinated upregulation of Th-1 chemokines, migration of Th-1 and cytotoxic T cells

213 Results showed that Km value of Th-MOF with TMB as a substrate is much lower than that o

214 We report that reduction of [Th(Tren(TIPS) )(OCP)] (2, Tren(TIPS) =[N(CH(2) CH(2) NSi

215 This response depended on Th cell expression of CD154 and Ag presentation by B cel

216 mmunity, indicating complex effects of RA on Th specification and the outcome of the immune response.

217 CMV-Tc and/or Th became (-) in 50% to 70% of these sero (+) patients a

218 sic Th9 cells (Th9(IL-4+TGF-beta)) and other Th cells, and are enriched for IL-1 and NF-kappaB gene s

219 accessibility for BATF is observed in other Th lineages and allows acquisition of the IL-9-secreting

220 The contribution of other Th cell subsets to B cell responses has not been fully e

221 the unperturbed tissue accumulation of other Th subsets (e.g., Th1 and Th17), highlighting that GM-CS

222 GM-CSF expression not only marks pathogenic Th cells, but that this subset mediates immunopathology

223 s that mimic chemotherapy in human patients, Th-MYCN mice develop genomic, microenvironmental, and cl

224 i, Cd, Co, Cr, Cu, K, Mn, Mo, Na, Ni, P, Pb, Th, Tl, Sb, U, V, Y and Zn) in 73 commercial products ma

225 Phox2b(+) /Nmb (+)) or C1 neurons (Phox2b(+)/Th (+)) with Channelrhodopsin-2.

226 4(+) (cluster of differentiation 4-positive) Th cells from 59 obese Hispanic and African American chi

227 ) and interleukin 17 (IL-17)/IL-22-producing Th cells (Th17/Th22) from mucosal sites and T follicular

228 phosphinidiide C-H bond activation product [{Th(Tren(TIPS) )}Th{N(CH(2) CH(2) NSiPr(i) (3) )(2) [CH(2

229 haring a common subunit, divergently promote Th cell development and expansion.

230 roved morphology of the donor-acceptor (PTB7-Th:NDP-V) blend, which is evidenced by the enhanced hole

231 sed low bandgap donor polymers, such as PTB7-Th.

232 Blocking IDO1 activity completely restored Th cell proliferation, but not IFN-gamma production.

233 a high enough capacity for production scale Th targets (50-100 g).

234 l honey (Al, As, Be, Ca, Cr, Mn, Mo, Ni, Se, Th and U), common heather (Co, K, Mg, Na, V), sage (Ag,

235 hermore, IL-3R expressing and IL-3-secreting Th cells were high in house dust mite-allergic patients.

236 Here, we have shown Th cell differentiation also imposes discrete motility g

237 tion between predatory common garter snakes (Th. sirtalis) and their toxic newt prey exhibiting hotsp

238 correlates with Malat1 in single Ag-specific Th cells from P. chabaudi chabaudi AS-infected mice and

239 nts showed that the presence of BCG-specific Th cells in previously BCG-vaccinated mice had a dose-sp

240 o the protein Ag PE in mice lacking specific Th cell subsets.

241 oligodendrocyte glycoprotein (MOG)-specific Th cells compared with Ppard (fl/fl) counterparts; the e

242 ds due to the formation of the highly stable Th(SO(4))(2) aqueous complex.

243 lateral compared with contralateral ROI (SUV(Th), 50-60 min summed data) at acute and chronic time po

244 rmined using the contralateral thalamus (SUV(Th)) as a pseudoreference region.

245 increased activated T cells, naive helper T (Th) and cytotoxic T cells, loss of CD56bright regulatory

246 esenting cells (APC) instruct CD4+ helper T (Th) cell responses, but it is unclear whether different

247 In a murine model, Alp1 elicits helper T (Th) cell-dependent lung eosinophilia that is initiated b

248 quires the specification of CD4(+) helper T (Th) cells into distinct fates, including Th1 cells that

249 l density and contents, as well as BV/TV, Tb.Th, Tb.N, and Tb.Sp.

250 polarization and maintenance of Th1 and Th17/Th 22, and anti-inflammatory/profibrogenic cytokines.

251 zation of globus pallidus (GP) and thalamus (Th) explains individual hemispheric biases in the abilit

252 he following four cycles, demonstrating that Th-MOF catalyst has outstanding stability.

253 Here, we demonstrate experimentally that Th, indeed, is highly mobile at temperatures between 175

254 These rules reveal that Th cells harness dynamic cytokine signaling to implement

255 Our results thus suggest that Th cell differentiation does not require specialized APC

256 mobility paradigm and strongly suggests that Th may be mobilized by some aqueous fluids.

257 nt in plants, and our evidence supports that Th. elongatum has gained Fhb7 through horizontal gene tr

258 The Th(III) ion and four oxygen donor atoms are coplanar to

259 The Th-Bi combination was too unstable to isolate, underscor

260 The Th-MYCN (CPM32) model therefore is a useful tool to diss

261 The Th-MYCN genetically engineered mouse model develops rapi

262 ith high concentrations of Th challenges the Th immobility paradigm and strongly suggests that Th may

263 dualizing therapy using MRI, to generate the Th-MYCN (CPM32) model.

264 ologic heterogeneity of neuroblastoma in the Th-MYCN transgenic model.

265 Platelets did not modulate the Th-1-polarizing cytokines IL-12 and IL-18.

266 differentiation and effector program of the Th subsets in the periphery are regulated by Satb1.

267 fects the overall solid-state packing of the Th-nitrato complexes but also influences the composition

268 s but also influences the composition of the Th-nitrato monomeric anions themselves.

269 EG ameliorates autoimmunity by targeting the Th 17-Tregs axis, making it a promising candidate drug f

270 7s, 6d and 5f orbital contributions to the Th-As bonds are suggested by quantum chemical calculatio

271 stoma confirmed the high degree to which the Th-MYCN model vascular phenotype recapitulated that of t

272 In conjunction with the Th(2A-CreER) and CGRPalpha-EGFP lines described previous

273 tural bond orbital analysis reveal that the [Th(6) O(8) ] clusters in 1 have a unique stable electron

274 In each of these Th cell subsets, a single transcription factor has been

275 trophenyl (PhNO(2)), phenyl (Ph), thiophene (Th), bithiophene (biTh), and dimethyl aniline (PhNMe(2))

276 -H bond activation product [{Th(Tren(TIPS) )}Th{N(CH(2) CH(2) NSiPr(i) (3) )(2) [CH(2) CH(2) SiPr(i)

277 Th2 cell levels) were performed according to Th cell responses in gingival tissues.

278 ulticycle treatment with cyclophosphamide to Th-MYCN mice, individualizing therapy using MRI, to gene

279 DC function and downstream events leading to Th polarization and immune modulation.

280 These results point to Th PRMT5 and its downstream cholesterol biosynthesis pat

281 from osteoarthritis or RA patients on total Th cells or different Th cell subsets of healthy donors

282 tion of a thorium-azide produces a transient Th=N triple bond, but this activates C-H bonds to produc

283 , Zr, Ba, Cs, Ba, La, Ce, Nd, Sm, Dy, Lu, U, Th) in glassy fallout from the first nuclear test, Trini

284 U-Th dating of travertine deposits shows leakage varies al

285 A major issue in thermochronology and U-Th-Pb dating is the effect of radiation damage, created

286 nce for aqueous alteration and modeling of U-Th-Pb isotope system evolution indicates that the latest

287 Here we present a new method based on U-Th-Pb isotope systems to assess if zircon crystals under

288 In agreement with a previously published (U-Th)/He thermochronology profile, our model shows that ro

289 ated luminescence dating of sediments with U-Th and palaeomagnetic analyses of flowstones to establis

290 Zircon (U-Th)/He dates for basement below the Great Unconformity a

291 d spanning 5.2 ka to 3.7 ka, dated with 25 U/Th ages that provide an average age uncertainty of 31 y

292 Here we present a 12,000 yr continuous U/Th-dated precipitation record from a Guatemalan speleoth

293 (+) T lymphocytes differentiate into various Th cell subsets following TCR binding to microbial pepti

294 of Akt signaling networks during Treg versus Th induction demonstrates that Akt differentially regula

295 ificantly lower IDO1 expression and a weaker Th cell suppressive capacity compared with osteoarthriti

296 42), one of the Rho-GTPases associated with Th-cell differentiation, was associated with downregulat

297 resent a pattern of features consistent with Th cell-like phenotype, including release of pertinent T

298 Surprisingly, infected mice with Th cell impairment experienced a compensatory neutrophil

299 be engaged in a TTX-mediated arms race with Th. couchii.

300 oaddition products that then decompose with [Th(Tren(TIPS) )O](-) essentially acting as a protecting