ライフサイエンスコーパス: Toll-like receptor 2

1 Male C57BL/6, wild-type, toll-like receptor 2-/-.

2 as pathogen-associated molecular patterns by Toll-like receptor 2.

3 C. glutamicumDeltamptD mutants, to activate Toll-like receptor 2.

4 feri was mediated primarily by activation of Toll-like receptor 2.

5 bs specific for the innate immunity receptor Toll-like receptor 2.

6 tivation of antigen-presenting cells through Toll-like receptor 2.

7 , heat shock protein 70 also signals through Toll-like receptor 2.

8 receptors expressed by macrophages, CD36 and toll-like receptor 2.

9 wide variety of pathogens likely detected by Toll-like receptor 2.

10 l stimulated HEK-293 cells expressing either Toll-like receptor 2/1 (TLR2/1) or TLR2/6, but only HspX

11 By directly downregulating Toll-like receptor 2/1 heterodimer (TLR2/1)-induced CYP2

12 kin-8 secretion, which did not occur through Toll-like receptor 2, 2/6, 4, or 5 stimulation.

13 r or father, IL-10 production in response to Toll-like receptor 2, 3, and 4 agonists, ovalbumin, salm

14 h healthy control subjects after exposure to toll-like receptor 2, 3, or 4 agonists or exposure to UV

15 igh-iron conditions had reduced responses to Toll-like receptor-2, -3, and -4 agonists, which associa

16 ugh pattern recognition receptors, including Toll-like receptors 2, 4, and 9.

17 Neutrophil Toll-like receptor 2, -4, and -9 expression and cytokine

18 Histone toxicity on glomeruli ex vivo was Toll-like receptor 2/4 dependent, and lack of TLR2/4 att

19 JQ1 also inhibited toll-like receptors 2/4 (TLR2/4) expression and nuclear

20 Increased NOX2 assembly required Toll-like receptors 2/4 and MyD88 signaling, which are k

21 treatment with a synergistic combination of Toll-like receptor 2/6 (TLR 2/6) and TLR9 agonists (Pam2

22 Both strains engaged with host Toll-like receptor 2/6 (TLR2/6), TLR2-CD14, and TLR5 to

23 The innate immune receptor, Toll-like receptor 2/6 heterodimer, is exploited by Sb(R

24 age-driven inflammation by modulation of the toll-like receptor 2/6 pathway.

25 lipids that have been previously reported as Toll-like receptor 2 activators.

26 Toll-like receptor 2 agonism activated luminal endotheli

27 Interestingly, maturation of MDLC with a toll-like receptor 2 agonist or transforming growth fact

28 inhibited NF-kappaB induced by IL-1beta and Toll-like receptor 2 agonist Pam3CSK4.

29 2, and IFNgamma upon stimulation with Con A, Toll-like receptor 2 agonist, or anti-CD3 antibodies.

30 es by peripheral monocytes stimulated with a Toll-like receptor 2 agonist.

31 Toll-like receptor 2-agonistic lipopeptides typified by

32 nting altered surface exposure or release of Toll-like receptor 2 agonists during rapid growth of Fra

33 or necrosis factor-alpha) following specific Toll-like receptor 2 and 4 (TLR-2/TLR-4) agonist challen

34 eneration and elevated surface expression of toll-like receptor 2 and CD11b on monocytes and neutroph

35 gen-activated kinase signaling downstream of Toll-like receptor 2 and dectin-1 stimulation.

36 with broad specificity that is dependent on Toll-like receptor 2 and interleukin 1beta.

37 s with previously identified risk alleles in Toll-like receptor 2 and TIRAP was associated with an ad

38 as compared to activation via heterodimeric Toll-like receptor 2 and Toll-like receptor 1 (TLR2/1) b

39 IFN-kappa was significantly increased after toll-like receptor 2 and UVB treatment in lupus keratino

40 attenuated pro-inflammatory responses toward Toll-like receptor-2 and -4 stimulation.

41 s, LPS-induced surface expression of MHC II, Toll-like receptor-2 and -4 were markedly lower (80%, P

42 hoic acid (LTA) and hemoglobin (Hb) requires Toll-like receptors 2 and 4 (TLR2 and -4).

43 Rationale: Toll-like receptors 2 and 4 (TLR2, TLR4) enable cellular

44 rance, as evidenced by the downregulation of Toll-like receptors 2 and 4 and of inflammatory cytokine

45 pneumophila resulted in the up-regulation of Toll-like receptors 2 and 4 and the activation of CD40,

46 nate immune activation and signaling through Toll-like receptors 2 and 4 at early times postinfection

47 atidylglycerol can inhibit the activation of toll-like receptors 2 and 4 of the innate immune system

48 HMGB1 functions as a ligand of Toll-like receptors 2 and 4 on macrophages, leading to a

49 on of different forms of Candida albicans by Toll-like receptors 2 and 4 on mononuclear leukocytes ha

50 Furthermore, HA signals through Toll-like receptors 2 and 4 to stimulate inflammatory ge

51 HIF IL-6 and IL-8 production independent of Toll-like receptors 2 and 4, receptor for advanced glyca

52 inflammatory immune responses by activating Toll-like receptors 2 and 4, respectively.

53 and OX40L expression on DCs, independent of Toll-like receptors 2 and 4, the NLRP3 inflammasome, and

54 nscription in mouse microglial cells through Toll-like receptors 2 and 4.

55 flammasome via caspase-8 and dimerization of Toll-like receptors 2 and 4.

56 s NFAT transcription factor independently of Toll-like receptors 2 and 4.

57 e inflammatory condition that is mediated by Toll-like receptors 2 and 6 (TLR2 and TLR6) and which in

58 ia activation of the innate immune receptor, Toll-like receptor 2, and subsequent inflammatory cell i

59 Dectin-1, Toll-like receptor 2, and Toll-like receptor 4 expressio

60 ionized calcium-binding adapter molecule 1, toll-like receptor 2, and toll-like receptor 4.

61 The data firmly establish Toll-like receptor 2 as an innate immune sensor for PGN

62 ted proteins on the AML-EV surface activated Toll-like receptor 2 as the initiating event of Akt/mTOR

63 mmasome and the bacterial lipoprotein sensor Toll-like receptor 2, but not in single knockout mice, d

64 As for MALP-2, all were dependent upon Toll-like receptor 2, but unlike MALP-2, they were also

65 AP)-containing) bacteria to demonstrate that Toll-like receptor 2 can recognize peptidoglycan (PGN).

66 osine kinase receptor-1, troponin I, soluble toll-like receptor-2, creatinine, and uric acid.

67 We demonstrate that Toll-like receptor 2-deficient (TLR2(-/-)) mice are resi

68 e in response is not because of variation in Toll-like receptor 2-dependent activation of the signali

69 amroQ mutant exhibited impaired induction of Toll-like receptor 2-dependent inflammatory responses fr

70 in vitro passages induce interleukin-6 in a Toll-like receptor 2-dependent manner.

71 ed disruption of the epithelial barrier in a Toll-like receptor 2-dependent manner.

72 of MMP-9, but not of MMP-1, was found to be Toll-like receptor 2-dependent.

73 roteasome proteolysis, by treatment of TLR2 (Toll-like receptor 2)-engaged and TLR7 (Toll-like recept

74 Toll-like receptor 2 expression was unchanged.

75 ensis infection induces an early increase in Toll-like receptor 2 expression, which facilitates paras

76 is bacterium evade immune recognition by the Toll-like receptor 2 family complex.

77 ingle-nucleotide polymorphisms (SNPs) in the toll-like receptor 2 gene (TLR2), the toll-like receptor

78 n host and pathogen is driving adaptation of Toll-like receptor 2 genes.

79 ciently inhibited the expression of IL-8 and Toll-like receptor 2 in M. furfur-infected human keratin

80 s induce the activation of NF-kappaB through Toll-like receptor 2, independent of enzymatic activity.

81 e are capable of inducing interleukin-6 in a Toll-like receptor 2-independent manner, whereas the dat

82 ntly suppressed T-lymphocyte activation in a Toll-like receptor 2-independent manner.

83 The interaction of F. alocis with Toll-like receptor 2 induced granule exocytosis along wi

84 mmensal bacteria by dendritic cells (through toll-like receptor 2), innate immune responses facilitat

85 Toll-like receptor 2 is the most diverse of these recept

86 TLR2 (Toll-like receptor 2) is a unique TLR in that it has bee

87 r membrane of A. muciniphila, interacts with Toll-like receptor 2, is stable at temperatures used for

88 nterferon knockout (IFN-gamma(-/-)), BALB/c, Toll-like receptor 2 knockout (TLR2(-/-)), and C57BL/6 m

89 (C3H/HeJ) or toll-like receptor-2 signaling (toll-like receptor-2 knockouts) had similar effects on p

90 r advanced glycation end products (RAGE) and Toll-like receptor 2, leading to local delivery of monoc

91 e skin microbiome is a rich source of LTA, a Toll-like receptor 2 ligand, we mimicked the GF microbio

92 ation factor, and lipoteichoic acid (LTA), a Toll-like receptor 2 ligand.

93 ity of Mtb-derived membrane vesicles bearing Toll-like receptor 2 ligands, including the lipoproteins

94 bed flow and of neutrophils, hyaluronan, and Toll-like receptor 2 ligation in superficial intimal inj

95 he ability of the whole organism to activate Toll-like receptor 2-mediated MyD88 signaling in macroph

96 ed production of nitric oxide synthase 2 via Toll-like receptor 2-mediated nuclear factor-kappaB acti

97 Toll-like receptor 2 mediates apolipoprotein CIII-induce

98 e was also a significant survival benefit in toll-like receptor 2-/- mice compared to wild-type mice.

99 Compared to septic wild-type mice, toll-like receptor 2-/- mice had markedly improved cardi

100 These favorable outcomes in toll-like receptor 2-/- mice were associated with attenu

101 Wild-type and toll-like receptor 2-/- mice were divided into sham and

102 ngivalis increased mRNA expressions of NOD2, Toll-like receptor 2, myeloid differentiation primary re

103 d enhance innate immune function and neither toll-like receptor-2 nor toll-like receptor-4 are necess

104 ession of key pattern recognition receptors (Toll-like receptor 2, Nucleotide-binding oligomerization

105 PSA induces and preferentially ligates Toll-like receptor 2 on PDCs but not on conventional DCs

106 f human beta-defensin-2) was not mediated by Toll-like receptor 2 or 4.

107 acrophages deficient in expression of either Toll-like receptor 2 or the Toll-like receptor accessory

108 PBMC cytolysis of leukemic cells, partly via Toll-like receptor-2/protein kinase C/nuclear factor-kap

109 ells, and CD14(+) monocytes that coexpressed Toll-like receptor-2, receptor-3, receptor-4, receptor-5

110 Furthermore, dectin-1 receptors rather than Toll-like receptor 2 receptors were shown to be necessar

111 oline-associated virulence is independent of Toll-like receptor 2 recognition.

112 Blocking of Toll-like receptor 2 reduced the strength of the observe

113 implicate flow disturbance, neutrophils, and Toll-like receptor 2 signaling as mechanisms that contri

114 d by PSA during intestinal inflammation, and Toll-like receptor 2 signaling is required for both Treg

115 These studies suggest that toll-like receptor 2 signaling plays a critical role in

116 toll-like receptor-4 signaling (C3H/HeJ) or toll-like receptor-2 signaling (toll-like receptor-2 kno

117 e from myeloid-derived suppressor cells in a Toll-like receptor 2/Stat3-dependent manner.

118 Innate Toll-like receptor 2 stimulation promotes formation of r

119 recognition with monoclonal antibody against Toll-like receptor 2 suggests that induction of innate i

120 side a universal T cell helper epitope and a Toll-like receptor 2 targeting lipid moiety to form lipo

121 universal T helper epitope, and a synthetic toll-like receptor 2-targeting moiety as a possible self

122 mune system, the mannose-binding lectin, and Toll-like receptor 2 that both specifies and amplifies t

123 ponse (e.g., tumor necrosis factor alpha and Toll-like receptor 2), the complement system, the respon

124 While Lpp activates Toll-like receptor 2, the MsbB acyltransferase modifies

125 nts expressed significantly higher levels of Toll-like receptor 2 (TLR-2) and exhibited significantly

126 d to explore the potential interplay between Toll-like receptor 2 (TLR-2) and NOD-2 in joint inflamma

127 er, BDCA1(+) mDCs expressed higher levels of Toll-like receptor 2 (TLR-2) and scavenger receptor A (S

128 s in order to characterize the expression of Toll-like receptor 2 (TLR-2) and TLR-4 and the responses

129 ity and was completely inhibited by blocking Toll-like receptor 2 (TLR-2) or depleting its mediator M

130 Maltoheptaose activated monocytes via Toll-like receptor 2 (TLR-2) signaling, as discovered by

131 In this study, we delivered signals through Toll-like receptor 2 (TLR-2) to reinvigorate functionali

132 ly to host cell CD36 and to the complex CD36-Toll-like receptor 2 (TLR-2), but not to TLR-2 alone or

133 ls, we conducted a study to test the role of Toll-like receptor 2 (TLR-2), TLR-4, and the cytosolic T

134 duce cell death in peritoneal B1a cells from Toll-like receptor 2 (TLR-2)- or NLRP3 inflammasome-defi

135 a range of bacteria and are able to activate Toll-like receptor 2 (TLR-2).

136 Toll-like receptor 2 (TLR-2)/TLR-4-mediated innate immun

137 f cultured bone marrow cells with ligands to Toll-like receptor 2 ([TLR-2] zymosan) and TLR-9 (ODN M3

138 Toll like receptor 2 (TLR2) recognizes lipids, activates

139 Our studies have demonstrated that Toll-like receptor 2 (TLR2) activation by HSV results in

140 Here, we show that toll-like receptor 2 (TLR2) activation by intracerebrove

141 Endothelial cell (EC) Toll-like receptor 2 (TLR2) activation up-regulates the

142 s trigger pro-inflammatory responses through Toll-like receptor 2 (TLR2) activation, and this whether

143 to regulate cytokine release induced by the Toll-like receptor 2 (TLR2) agonist Pam3CSK4.

144 Toll-like receptor 2 (TLR2) agonists are lipopeptides po

145 have reported that it can be an agonist for Toll-like receptor 2 (TLR2) and an antagonist or agonist

146 activate innate immune responses by engaging Toll-like receptor 2 (TLR2) and are highly immunostimula

147 le mice and (ii) whether host chitin-binding Toll-like receptor 2 (TLR2) and CD14 are required for th

148 reviously, we have reported that ligation of Toll-like receptor 2 (TLR2) and Dectin 1 on antigen-pres

149 how that two pathogen recognition receptors, Toll-like receptor 2 (TLR2) and dectin-1, recognizing th

150 Both Toll-like receptor 2 (TLR2) and IL-1 receptor type 1 (IL

151 s and astrocytes through a pathway involving Toll-like receptor 2 (TLR2) and poly(ADP-ribose) polymer

152 antibodies were used to dissect the role of Toll-like receptor 2 (TLR2) and programmed death-ligand

153 e the ability of the innate sensing molecule Toll-like receptor 2 (TLR2) and the signaling molecule M

154 tion was inhibited by blocking antibodies to Toll-like receptor 2 (TLR2) and TLR1, indicating that hu

155 Finally, we observed that killed BCG, Toll-like receptor 2 (TLR2) and TLR4 agonists, and an M

156 se to other proinflammatory stimuli, such as Toll-like receptor 2 (TLR2) and TLR4 agonists.

157 minor reduction in mice doubly deficient in Toll-like receptor 2 (Tlr2) and Tlr4 and normal response

158 naling was TLR-dependent as the knockdown of Toll-like receptor 2 (TLR2) and TLR4 blocked NFkappaB an

159 n and IL-1beta secretion in macrophages upon Toll-like receptor 2 (TLR2) and TLR4 engagement.

160 Toll-like receptor 2 (TLR2) and TLR4 expression was dete

161 This study examined the role that Toll-like receptor 2 (TLR2) and TLR4 may play in pathoge

162 Here we show that miR-302b is induced by Toll-like receptor 2 (TLR2) and TLR4 through ERK-p38-NF-

163 lis, a gram-negative bacterium recognized by Toll-like receptor 2 (TLR2) and TLR4, which are expresse

164 ved features, many viruses are recognized by Toll-like receptor 2 (TLR2) and TLR4.

165 Toll-like receptor 2 (TLR2) and TLR5 have been shown to

166 e previously shown to engage human and mouse Toll-like receptor 2 (TLR2) and to inhibit mouse osteobl

167 A. actinomycetemcomitans or P. gingivalis is Toll-like receptor 2 (TLR2) and/or TLR4 dependent.

168 ed, albeit the recognition of lipoglycans by Toll-like receptor 2 (TLR2) appears to be important for

169 Agonists of Toll-like receptor 2 (TLR2) are devoid of significant pr

170 ferentiation 14 (CD14) and the transmembrane toll-like receptor 2 (TLR2) are important receptors in t

171 Complement Receptor 3 (CR3) and Toll-like Receptor 2 (TLR2) are pattern recognition rece

172 thelial cell lines, we previously identified Toll-like receptor 2 (TLR2) as the principal epithelial

173 t VCAN exerts tolerogenic activities through Toll-like receptor 2 (TLR2) binding, the immunoregulator

174 nate immune responses via the utilization of Toll-like receptor 2 (TLR2) but not TLR4.

175 rlying mechanism revealed that activation of Toll-like receptor 2 (TLR2) by curli fibers is critical

176 mplicated in preventing inflammation through Toll-like receptor 2 (TLR2) by inducing expression of th

177 Toll-like receptor 2 (TLR2) deficiency enhances murine s

178 ation in HeLa cells, likely due to a lack of Toll-like receptor 2 (TLR2) expression in these cells.

179 neumococcal clearance was not dependent upon Toll-like receptor 2 (TLR2) expression, oxidative stress

180 tantly, this colitis was highly dependent on Toll-like receptor 2 (TLR2) function since it was suppre

181 Toll-like receptor 2 (TLR2) has been implicated in the o

182 morphism in the Toll-IL-1 receptor domain of Toll-like receptor 2 (TLR2) has been linked to increased

183 We examined the inflammatory role of Toll-like receptor 2 (TLR2) in age-related macular degen

184 en gram-positive bacterial superantigens and toll-like receptor 2 (TLR2) in health and critical illne

185 To examine the role of Toll-like receptor 2 (TLR2) in host defense against Stre

186 ng cluster for the interaction of LipL32 and Toll-like receptor 2 (TLR2) in induced inflammatory resp

187 ycobacterium tuberculosis, to synergize with Toll-like receptor 2 (TLR2) in mediating these responses

188 lipopolysaccharide that supposedly activates toll-like receptor 2 (TLR2) instead of TLR4.

189 Toll-like receptor 2 (TLR2) is a pattern recognition rec

190 Toll-like receptor 2 (TLR2) is a pattern recognition rec

191 Toll-like receptor 2 (TLR2) is a target for immune syste

192 Toll-like receptor 2 (TLR2) is an essential mediator of

193 Toll-like receptor 2 (TLR2) is an innate immune receptor

194 We report here that Toll-like receptor 2 (TLR2) is expressed by oligodendroc

195 Toll-like receptor 2 (Tlr2) is important for its role in

196 We next observed that Toll-like receptor 2 (TLR2) is suppressed in BMMPhi from

197 Although the pattern recognition receptor Toll-like receptor 2 (TLR2) is typically thought to reco

198 ssion profile was similar to that induced by toll-like receptor 2 (TLR2) ligand Pam3Cys, but differen

199 Previously, we showed that Toll-like receptor 2 (TLR2) ligand pretreatment prevente

200 l-(l ysyl)3-lysine (Pam3CysSK4), a synthetic Toll-like receptor 2 (TLR2) ligand, that was given at im

201 In the intestines, Toll-like receptor 2 (TLR2) mediates immune responses to

202 We found neither Toll-like receptor 2 (TLR2) nor TLR4 nor TLR5 were requi

203 creened for their ability to either activate Toll-like receptor 2 (TLR2) or TLR4 and to antagonize TL

204 However, eliminating Toll-like receptor 2 (TLR2) permits bacterial replicatio

205 Toll-like receptor 2 (TLR2) plays a critical role in hos

206 Toll-like receptor 2 (TLR2) plays a key role in innate i

207 Here, we demonstrate that toll-like receptor 2 (TLR2) plays a role in the NK cell-

208 he present study was to assess the effect of Toll-like receptor 2 (TLR2) polymorphisms on susceptibil

209 study continues to explore the plasticity of Toll-like receptor 2 (TLR2) previously described in immu

210 respiratory epithelial cells in response to toll-like receptor 2 (TLR2) receptor stimulation.

211 athogen Porphyromonas gingivalis activates a Toll-like receptor 2 (TLR2) response that triggers infla

212 Loss of Toll-like receptor 2 (TLR2) resulted in reduced islet ex

213 Both interleukin-1 receptor (IL-1R) and toll-like receptor 2 (TLR2) signal via the adapter molec

214 We have previously demonstrated that toll-like receptor 2 (TLR2) signaling is critical for ne

215 Macrophage activation depended on Toll-like receptor 2 (TLR2) signaling, and cytokine prod

216 e the most potent microbial agonists for the Toll-like receptor 2 (TLR2) subfamily, and this pattern

217 nts with rosacea expressed higher amounts of Toll-like receptor 2 (TLR2) than normal patients.

218 this study, we examined the contribution of Toll-like receptor 2 (TLR2) to host resistance against M

219 shed work indicates that the contribution of Toll-like receptor 2 (TLR2) to host resistance during ac

220 ingivalis activate cross talk signaling from Toll-like receptor 2 (TLR2) to the beta2 integrin CD11b/

221 Toll-like receptor 2 (TLR2) was important to this proces

222 e ability of peptidoglycan (PGN) to activate Toll-like receptor 2 (TLR2) was recently questioned, we

223 olonization are in part due to activation of Toll-like receptor 2 (TLR2), a receptor for lipoproteins

224 crophages to produce TNF-alpha primarily via Toll-like receptor 2 (TLR2), although late pneumococcal

225 Both are ligands for the cell surface Toll-like receptor 2 (TLR2), and thus the contribution o

226 es in the proinflammatory markers TNF-alpha, toll-like receptor 2 (TLR2), and TLR4.

227 stress response was found to be dependent on Toll-like receptor 2 (TLR2), as evident by reduced expre

228 ns of carboxyalkylpyrroles are recognized by Toll-like receptor 2 (TLR2), but not TLR4 or scavenger r

229 tool in vivo by analysing the expression of toll-like receptor 2 (TLR2), corresponding to the microg

230 that the innate immune recognition receptor, Toll-like receptor 2 (TLR2), is crucial for inflammatory

231 ond to Pneumocystis murina organisms through Toll-like receptor 2 (TLR2), leading to the nuclear tran

232 We found that RIP2, but not toll-like receptor 2 (TLR2), played a critical role in t

233 osteoclast modulation through engagement of Toll-like receptor 2 (TLR2), though the factors responsi

234 i-SBR immune response in mice and to require Toll-like receptor 2 (TLR2), TLR4, and MyD88 signaling f

235 ggering of mouse peritoneal neutrophils with Toll-like receptor 2 (TLR2), TLR4, and TLR9 ligands, but

236 ional type I IFN receptor but independent of Toll-like receptor 2 (TLR2), TLR4, TLR9, and the adapter

237 connect a key pattern recognition receptor, Toll-like receptor 2 (TLR2), to hyperbilirubinemia-induc

238 In vitro activation of Toll-like receptor 2 (TLR2), up-regulated in ENL lesions

239 lipopeptide Pam3CysSK4, a popular agonist of Toll-like receptor 2 (TLR2), were designed making use of

240 Toll-like receptor 2 (TLR2), which increases CTMP induct

241 Toll-like receptor 2 (TLR2), which recognizes a range of

242 l" anti-inflammatory phenotype by activating Toll-like receptor 2 (TLR2), which regulates the inducti

243 We show that increased activation of Toll-like receptor 2 (TLR2)- and MyD88-dependent signali

244 he Brucella effector protein TcpB suppresses Toll-like receptor 2 (TLR2)- and TLR4-mediated innate im

245 n of macrophages derived from MyD88-, TRIF-, Toll-like receptor 2 (TLR2)-, TLR4-, and TLR2/4-deficien

246 and bacterial translocation were assessed in Toll-like receptor 2 (TLR2)-deficient and tumor necrosis

247 ural killer T cells, fails to enhance EAE in Toll-like receptor 2 (TLR2)-deficient mice and, in vitro

248 induces MCP-1 up-regulation in the SLFs via Toll-like receptor 2 (TLR2)-dependent activation of NF-k

249 es in infected macrophages are all driven by Toll-like receptor 2 (TLR2)-dependent activation of the

250 ral pathogen Porphyromonas gingivalis induce Toll-like receptor 2 (TLR2)-dependent macrophage activat

251 d COX2 expression, which were augmented in a Toll-like receptor 2 (TLR2)-dependent manner by macropha

252 a3 activation and P-selectin expression in a Toll-like receptor 2 (TLR2)-dependent manner.

253 ophilic pulmonary inflammation, mainly via a Toll-like receptor 2 (TLR2)-dependent mechanism.

254 n induces pathogenic host inflammation via a Toll-like receptor 2 (TLR2)-dependent pathway, resulting

255 nfected with LASV or with LCMV-WE suppressed Toll-like receptor 2 (TLR2)-dependent proinflammatory cy

256 matory reactions in gingival fibroblasts and Toll-like receptor 2 (TLR2)-dependent secretion of inter

257 y diminished capacity to stimulate host cell Toll-like receptor 2 (TLR2)-dependent signaling and inte

258 This study investigated responses to Toll-like receptor 2 (TLR2)-driven extracellular signal-

259 ose-dependent NF-kappaB reporter activity in Toll-like receptor 2 (TLR2)-expressing HEK293T cells and

260 ibited responses to specific ligands for the Toll-like receptor 2 (TLR2)-TLR6 heterodimer.

261 teraction between the viral glycoprotein and Toll-like receptor 2 (TLR2).

262 ylococcus aureus (S.a.), which are sensed by Toll-like receptor 2 (TLR2).

263 r glial fibrillary acidic protein (GFAP) and Toll-like receptor 2 (TLR2).

264 ability of aberrant forms of LOS to activate Toll-like receptor 2 (TLR2).

265 any pattern recognition receptors, including Toll-like receptor 2 (TLR2).

266 ibition of osteoblasts through engagement of Toll-like receptor 2 (TLR2).

267 organisms, mediates inflammation through the Toll-like receptor 2 (TLR2).

268 decreased ability to activate NF-kappaB via Toll-like receptor 2 (TLR2).

269 (CMV) is initiated after its recognition by Toll-like receptor 2 (TLR2).

270 iduct pathology because it fails to activate Toll-like receptor 2 (TLR2).

271 This effect of SAA is dependent on Toll-like receptor 2 (TLR2).

272 nterleukin-10 (IL-10) through stimulation of Toll-like receptor 2 (TLR2).

273 elicit innate immune responses by activating Toll-like receptor 2 (TLR2).

274 in both human and mouse cells dependent upon Toll-like receptor 2 (TLR2).

275 88 (MyD88), TANK binding kinase 1 (TBK1), or Toll-like receptor 2 (TLR2).

276 ction with the pattern recognition receptor, Toll-like receptor 2 (TLR2).

277 is typically initiated by interactions with Toll-like receptor 2 (TLR2).

278 animal model for multiple sclerosis, through Toll-like receptor 2 (TLR2).

279 strated their differentiation in vitro after Toll-like receptor 2 (TLR2)/MyD88 stimulation.

280 own that curli fibrils are recognized by the Toll-like receptor 2 (TLR2)/TLR1 heterodimer complex.

281 The Toll-like receptor 2 (TLR2)/TLR1 receptor complex respon

282 ncoding the anti-apoptotic protein BIRC3 and Toll-like receptor 2 (TLR2); and the chromatin modifiers

283 ediated by the pathogen recognition receptor Toll-like receptor 2 (TLR2); furthermore, Legionella ind

284 stimulates the innate immune system through Toll-like receptor 2 (TLR2); however, the pathogen-assoc

285 Mice deficient in Toll-like receptor 2 (TLR2-/-) or in B and T cells (scid

286 scle (ASM) cells, we show that activation of toll-like receptor 2 (TLR2; mimicking bacterial infectio

287 vators of the pattern recognition receptors, toll-like receptor-2 (TLR2) and -4 (TLR4).

288 Rv1168c interacts specifically with Toll-like receptor-2 (TLR2) resulting in downstream acti

289 ty by increasing pattern recognition through Toll-like receptor-2 (TLR2), and increasing the expressi

290 ast, when we transferred neutrophils lacking Toll-like receptor-2 (TLR2), TLR3, TLR4, TLR7 and TLR9,

291 attern recognition receptor dectin-1 but not Toll-like receptor-2 (TLR2), zymosan-mediated RGC regene

292 his article, we show that germ-free (GF) and Toll-like receptor-2 (Tlr2)-deficient mice have reduced

293 Emerging reports reveal that activating Toll-like receptor-2 (TLR2)-MyD88 signals in CD8 T lymph

294 Upon microbial infection or Toll-like-receptor 2 (TLR2) activation, Rubicon interact

295 ced early during IAPP aggregation provided a Toll-like-receptor-2- (TLR2-) dependent stimulus for NF-

296 e I interferon (IFN) signaling downstream of Toll-like receptor 2/Toll-like receptor 4 activation in

297 l, and parasitic infections, such as through Toll-like receptor 2-triggered degranulation, secretion

298 mphoblastoid cell lines (LCLs) partially via Toll-like receptor 2 triggering, as did purified GAS pep

299 gamma (IFN-gamma), interleukin-6 (IL-6), and toll-like receptor 2 (TRL-2).

300 Toll-like receptor 2 was shown to be activated in AD les