ライフサイエンスコーパス: Treponema pallidum

1 ens (e.g. Helicobacter pylori, C. jejuni and Treponema pallidum).

2 e asymptomatic when they are reinfected with Treponema pallidum.

3 lopment following intradermal challenge with Treponema pallidum.

4 hesin Tp0751 within the spirochete bacterium Treponema pallidum.

5 e of the related syphilis-causing spirochete Treponema pallidum.

6 disease caused by the spirochetal bacterium Treponema pallidum.

7 ermini of the 17- and 47-kDa lipoproteins of Treponema pallidum.

8 from the emergence of phenotypic variants of Treponema pallidum.

9 se of humans caused by spirochetal bacterium Treponema pallidum.

10 lated oral spirochetes (PROS) are related to Treponema pallidum.

11 ctivation by motile Borrelia burgdorferi and Treponema pallidum.

12 or by identification of the causative agent, Treponema pallidum.

13 n identified previously in OM fractions from Treponema pallidum.

14 nd characterized in Treponema phagedenis and Treponema pallidum.

15 vage site, and has 26% identity with TmpC of Treponema pallidum.

16 bacterial infection caused by the bacterium Treponema pallidum.

17 mydia trachomatis, Neisseria gonorrhoeae, or Treponema pallidum.

18 n (TMA) assay for the detection of rRNA from Treponema pallidum.

19 is a sexuality transmitted disease caused by Treponema pallidum.

20 eraction datasets of Helicobacter pylori and Treponema pallidum.

21 philis is caused by the spirochetal pathogen Treponema pallidum.

22 ) for herpes simplex virus, and 27 (19%) for Treponema pallidum; 12 (8%) were positive for > 1 organi

23 Neurosyphilis was defined as detection of Treponema pallidum 16S RNA in CSF or CSF white blood cel

24 Syphilis is an infectious disease caused by Treponema pallidum, a gram-negative, spirochete bacteriu

25 Synthetic analogs of lipopeptides from Treponema pallidum also inhibited Ag processing.

26 The Tp34 (TP0971) membrane lipoprotein of Treponema pallidum, an obligate human pathogen and the a

27 Treponema pallidum, an obligate parasite of humans and t

28 Immunoblots using anti-FlaA serum from Treponema pallidum and a lysate of B. burgdorferi showed

29 is increasing evidence that lipoproteins of Treponema pallidum and Borrelia burgdorferi are key infl

30 Lipoproteins of Treponema pallidum and Borrelia burgdorferi possess pote

31 spirochetes including the syphilis bacterium Treponema pallidum and Lyme disease pathogen Borrelia bu

32 of Escherichia coli, Haemophilus influenzae, Treponema pallidum and Mycoplasma genitalium.

33 Treponema pallidum and other members of the genera Trepo

34 of the organisms Caenorhabditis elegans and Treponema pallidum and to differ by one residue from PEP

35 Treponema pallidum and Treponema denticola encode within

36 me disease (Borrelia burgdorferi), syphilis (Treponema pallidum) and leptospirosis (Leptospira interr

37 etected nucleic acid target (tpp47 gene from Treponema pallidum) and nitrite ions in an aqueous sampl

38 r antibodies to herpes simplex virus type 2, Treponema pallidum, and hepatitis B, tests for hepatitis

39 ion of DNA targets from Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV) types

40 ction (M-PCR) assay for Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV) was c

41 eaction assay to detect Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV); sera

42 al ulcer disease (GUD), Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus, was used t

43 ly related proteins in Borrelia burgdorferi, Treponema pallidum, and Leptospira kirschneri.

44 eins/lipopeptides from Borrelia burgdorferi, Treponema pallidum, and Mycoplasma fermentans activated

45 y of bacteria, such as Borrelia burgdorferi, Treponema pallidum, and Mycoplasma fermentans.

46 Western blot analysis using Treponema pallidum anti-FlaA serum indicated that FlaA w

47 t [FTA-ABS], microhemagglutination assay for Treponema pallidum antibodies [MHA-TP], Treponema pallid

48 or the detection of C-Reactive Protein, anti-Treponema pallidum antibodies and E. coli bacteria.

49 d electronic reader for detection of HIV and Treponema pallidum antibodies in 450 previously characte

50 um samples and compared to reference HIV and Treponema pallidum antibody detection methods.

51 mology with the sequences of E. coli Dps and Treponema pallidum antigen TpF1 or 4D, proteins which as

52 rex Diagnostics) that uses three recombinant Treponema pallidum antigens (TpN15, TpN17, and TpN47) an

53 ively detects IgG and IgM antibodies against Treponema pallidum antigens in human serum and plasma.

54 lopment of the T-cell response to a panel of Treponema pallidum antigens over the course of syphilis

55 resence of antibodies reactive with specific Treponema pallidum antigens.

56 Phagocytosis of Treponema pallidum by cytokine-activated macrophages aid

57 ly detected ulcers were tested for HSV-2 and Treponema pallidum by polymerase chain reaction (PCR).

58 Unlike many pathogenic bacteria, Treponema pallidum cannot synthesize riboflavin; we rece

59 rom a few eubacteria (Clostridium difficile, Treponema pallidum, Chlorobium tepidum).

60 Introduction of 1 Treponema pallidum complex pathogen in naive European po

61 The genomes of Treponema denticola and Treponema pallidum contain a gene, licCA, which is predi

62 Surprisingly, opsonophagocytosis of Treponema pallidum did not elicit a discernible cell dea

63 We evaluated the presence of Treponema pallidum DNA (TP-DNA) in various sample types

64 Treponema pallidum DNA from even small numbers of organi

65 Treponema pallidum DNA in blood and rRNA in CSF were det

66 rase chain reaction (PCR) was used to detect Treponema pallidum DNA in cerebrospinal fluid (CSF) from

67 e used real-time quantitative PCR to measure Treponema pallidum DNA levels in rabbits infected intrat

68 The prevalence of Treponema pallidum DNA was examined in the following sev

69 Treponema pallidum DNA was isolated from 158 patients wi

70 Previous studies demonstrated that Treponema pallidum encodes a cluster-9 (C9) ABC transpor

71 eran Affairs facility, finding 5.5% reactive Treponema pallidum enzyme immunoassay (EIA) tests.

72 e evaluated a molecular subtyping system for Treponema pallidum for its ability to differentiate betw

73 ficiency virus gene (HIV), and the syphilis (Treponema pallidum) gene.

74 The recent discovery that the Treponema pallidum genome encodes 12 orthologs of the Tr

75 s were predicted by computer analysis of the Treponema pallidum genome.

76 the United States, yet little is known about Treponema pallidum genomic epidemiology within American

77 obtained with standard laboratory tests (the Treponema pallidum haemagglutination assay [TPHA] and th

78 polymerase chain reaction (M-PCR) to detect Treponema pallidum, Haemophilus ducreyi, and herpes simp

79 A multiplex Treponema pallidum-Haemophilus ducreyi loop-mediated iso

80 To date, however, genomic studies of Treponema pallidum have focused mainly on the northern h

81 varied genome sizes (Mycoplasma pneumoniae, Treponema pallidum, Helicobacter pylori, Campylobacter j

82 tion assay (CSF-TPPA) is sensitive and a CSF Treponema pallidum hemagglutination assay (CSF-TPHA) tit

83 pid plasma reagin [RPR] titer > or = 1:8 and Treponema pallidum hemagglutination assay [TPHA]/fluores

84 asma reagin titer > or = 1 :8 and a positive Treponema pallidum hemagglutination assay or indirect fl

85 a focus on alternative agglutination assays (Treponema pallidum hemagglutination assays, TPHAs) as th

86 munoassay for the detection of HIV-1, HIV-2, Treponema pallidum, hepatitis B virus (HBV), hepatitis C

87 unts, and serologic assays for antibodies to Treponema pallidum, herpes simplex virus, and hepatitis

88 be a false-positive reaction by nonreactive Treponema pallidum immobilization and fluorescent trepon

89 polymerase chain reaction (PCR) testing for Treponema pallidum in cerebrospinal fluid (CSF) samples.

90 sensitive and specific PCR method to detect Treponema pallidum in clinical specimens was developed.

91 human remains reflecting a high diversity of Treponema pallidum in early modern Europe.

92 may prove to be useful techniques to detect Treponema pallidum in intraocular specimens.

93 hilis and invasion of cerebrospinal fluid by Treponema pallidum in patients with human immunodeficien

94 ons of syphilis and the invasive behavior of Treponema pallidum in tissue culture systems reflect the

95 Direct detection methods for Treponema pallidum include dark-field microscopy (DFM),

96 The species Treponema pallidum includes three subspecies (pallidum,

97 Treponema pallidum includes three subspecies of antigeni

98 d to examine mechanisms that likely underlie Treponema pallidum-induced immune cell activation and co

99 We documented urethral Treponema pallidum infection in a man with nongonococcal

100 Identification of infants with Treponema pallidum infection of the central nervous syst

101 imary, secondary, or early latent) syphilis (Treponema pallidum infection).

102 philis is an inflammatory eye disease due to Treponema pallidum infection.

103 Treponema pallidum infections can have severe complicati

104 The 15-kDa lipoprotein of Treponema pallidum is a major immunogen during natural s

105 Treponema pallidum is cleared from sites of infection by

106 ions of syphilis and the infecting strain of Treponema pallidum is not known.

107 e genome of the etiologic agent of syphilis, Treponema pallidum, is compact and devoid of many metabo

108 In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most

109 Treponema pallidum, its membrane lipoproteins, and synth

110 The molecular masses of Tromp1, three Treponema pallidum lipoproteins, and a bovine serum albu

111 that this protein shares similarity with the Treponema pallidum LRR (LRR(TP)) family of proteins and

112 rrelia burgdorferi and by B. burgdorferi and Treponema pallidum lysates but were poorly activated by

113 The nucleotide sequence of the Treponema pallidum mcp2 gene was determined.

114 followed by microhemagluttination assay for Treponema pallidum (MHA-TP) testing of RPR-reactive sera

115 compared the microhemagglutination assay for Treponema pallidum (MHA-TP), a treponemal test, with two

116 test and the microhemagglutination assay for Treponema pallidum (MHA-TP).

117 tive by another treponema-specific test, the Treponema pallidum microhemagglutination assay.

118 s were used: a nonimmune group infected with Treponema pallidum (NI/TP), a nonimmune group injected w

119 ettsia rickettsii, Chlamydia group positive, Treponema pallidum, Orientia tsutsugamushi, Fransciscell

120 TroA (Tromp1) was initially reported to be a Treponema pallidum outer membrane protein with porin-lik

121 Immunization with purified Treponema pallidum outer membrane vesicles (OMV) has pre

122 sequences from a 26-kDa protein in isolated Treponema pallidum outer membranes (OMs).

123 Recent reports that isolated Treponema pallidum outer membranes contain an ortholog f

124 culosis), Mycobacterium leprae (leprosy) and Treponema pallidum pallidum (syphilis).

125 with two other treponemal tests, the Serodia Treponema pallidum particle agglutination (TP-PA) assay

126 chemiluminescence immunoassay (CLIA), and a Treponema pallidum particle agglutination (TP-PA) test.

127 ther tested by rapid plasma reagin (RPR) and Treponema pallidum particle agglutination (TP.PA) testin

128 lis has been impacted by a withdrawal of the Treponema pallidum particle agglutination (TPPA) assay f

129 The Treponema pallidum particle agglutination (TPPA) assay i

130 flex testing with rapid plasma reagin (RPR), Treponema pallidum particle agglutination (TPPA), and fl

131 [FTA] assay [Zeus Scientific, Raritan, NJ], Treponema pallidum particle agglutination [TP-PA; Fujire

132 and Trep-Sure EIA) and three manual assays (Treponema pallidum particle agglutination [TP-PA], fluor

133 ed data suggest that the cerebrospinal fluid Treponema pallidum particle agglutination assay (CSF-TPP

134 al serology underwent reflexive testing with Treponema pallidum particle agglutination assay (TP-PA)

135 , RPR-negative serology were tested with the Treponema pallidum particle agglutination assay (TP-PA)

136 LIA (line immunoassay); (5) LIAISON CIA; (6) Treponema pallidum particle agglutination assay (TPPA);

137 for Treponema pallidum antibodies [MHA-TP], Treponema pallidum particle agglutination assay [TP-PA])

138 sly evaluated using the rapid plasma reagin, Treponema pallidum particle agglutination, and chemilumi

139 ative rapid plasma reagin (RPR) test and the Treponema pallidum passive particle agglutination (TP-PA

140 Western blot analysis using antisera to Treponema pallidum PF proteins along with N-terminal ami

141 Treponema pallidum prevalence and burden at oral and les

142 complete genomes of Borrelia burgdorferi and Treponema pallidum provides a number of insights into ev

143 Treponema pallidum rapidly disseminates from a genital s

144 e have previously observed that while native Treponema pallidum rare outer membrane protein 1 (Tromp1

145 Treponema pallidum rare outer membrane protein 1 (Tromp1

146 Identification of Treponema pallidum rare outer membrane proteins (OMPs) h

147 Definitive identification of Treponema pallidum rare outer membrane proteins (OMPs) h

148 aggregates the low-density membrane-spanning Treponema pallidum rare outer membrane proteins (TROMPs)

149 Treponema pallidum reacts poorly with the antibodies pre

150 logical testing and an experimental 23S rRNA Treponema pallidum real-time transcription-mediated ampl

151 la, as well as the parental ortholog for the Treponema pallidum repeat (Tpr) family in the syphilis s

152 It has been shown that the Treponema pallidum repeat protein K (TprK) differs in se

153 When used as an immunogen, Treponema pallidum repeat protein K (TprK) has been show

154 ts immunized with the Seattle Nichols strain Treponema pallidum repeat protein K (TprK) were previous

155 We previously identified Treponema pallidum repeat proteins TprC/D, TprF, and Tpr

156 The tpr (Treponema pallidum repeat) genes are believed to code fo

157 anscription-mediated amplification assay for Treponema pallidum (RUO T. pallidum TMA) yields instance

158 This rapid assay detected HIV and Treponema pallidum serum antibodies with sensitivities o

159 of the spirochaetes Borrelia burgdorferi and Treponema pallidum show strong strand-specific skews in

160 SORs from Desulfovibrio gigas and Treponema pallidum showed similar turnover rates when su

161 suggest the induction of local and systemic Treponema pallidum-specific CD4+ T-cell responses to T.

162 creening tests (antilipoidal antibodies) and Treponema pallidum-specific tests (anti-T. pallidum anti

163 me-wide analysis of the syphilis spirochete, Treponema pallidum ssp.

164 Transcriptional regulation in Treponema pallidum ssp. pallidum is poorly understood, p

165 onfers macrolide resistance is present in >1 Treponema pallidum strain, 58 isolates collected between

166 techniques that allow the differentiation of Treponema pallidum strains on the basis of two variable

167 ent doxycycline usage might select resistant Treponema pallidum strains.

168 059G) in both copies of the 23S rRNA gene in Treponema pallidum strains.

169 ous bacterial PCR was initially positive for Treponema pallidum, subsequent PCR was negative prior to

170 Treponema pallidum subsp pertenue and Haemophilus ducrey

171 n lesions or presence of ulcers negative for Treponema pallidum subsp pertenue on PCR, and active yaw

172 r PCR pre-amplification of the tpp47 gene of Treponema pallidum subsp.

173 caused by the sexually transmitted bacterium Treponema pallidum subsp.

174 n metagenomic sequencing for the presence of Treponema pallidum subsp.

175 recently, the infectious agent of syphilis, Treponema pallidum subsp.

176 e further adapt this approach to distinguish Treponema pallidum subsp.

177 of the 15-kDa gene have been determined for Treponema pallidum subsp. pallidum (Nichols and Bal-3 st

178 tive transport related operon (tro) locus of Treponema pallidum subsp. pallidum (Nichols strain) (Tp)

179 transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated fr

180 Transcriptional analysis of the tpr genes in Treponema pallidum subsp. pallidum (referred to here as

181 s, is morphologically indistinguishable from Treponema pallidum subsp. pallidum (T. pallidum), the hu

182 A 38-kDa lipoprotein of Treponema pallidum subsp. pallidum (T. pallidum), the sy

183 this bacterial infection, which is caused by Treponema pallidum subsp. pallidum (TPA), has been re-em

184 s in Cuba prompted us to map the circulating Treponema pallidum subsp. pallidum allelic profiles in t

185 The clearance of Treponema pallidum subsp. pallidum from early syphilis l

186 In silico analyses of Treponema pallidum subsp. pallidum genomes and predicted

187 ons have demonstrated that immunization with Treponema pallidum subsp. pallidum glycerophosphodiester

188 The spirochete Treponema pallidum subsp. pallidum is the causative agen

189 Treponema pallidum subsp. pallidum is the causative agen

190 and expression of the gene encoding a 28-kDa Treponema pallidum subsp. pallidum rare outer membrane p

191 and sequencing of the gene encoding a 31-kDa Treponema pallidum subsp. pallidum rare outer membrane p

192 908 of the 1,039 proteins in the proteome of Treponema pallidum subsp. pallidum using a protein array

193 ly mapping the 47-kDa lipoprotein (Tpp47) of Treponema pallidum subsp. pallidum using an overlapping

194 ction of the predicted lipoprotein TP0136 of Treponema pallidum subsp. pallidum were investigated bas

195 ent Tpr proteins in the syphilis spirochete, Treponema pallidum subsp. pallidum, may have important i

196 syphilis, caused by the spirochete bacterium Treponema pallidum subsp. pallidum, remains a public hea

197 In Treponema pallidum subsp. pallidum, the agent of syphili

198 Treponema pallidum subsp. pallidum, the agent of syphili

199 The tpr gene family of Treponema pallidum subsp. pallidum, the causative agent

200 The tprK gene of Treponema pallidum subsp. pallidum, the causative agent

201 Treponema pallidum subsp. pallidum, the causative agent

202 n occurs in surface-exposed proteins, and in Treponema pallidum subsp. pallidum, the syphilis agent,

203 The tprK gene in the syphilis spirochete, Treponema pallidum subsp. pallidum, undergoes antigenic

204 uence of the bacterium that causes syphilis, Treponema pallidum subsp. pallidum.

205 C4D guinea pigs to cutaneous infection with Treponema pallidum subsp. pertenue Haiti B strain.

206 ribing the use of DNA sequencing to identify Treponema pallidum subsp. pertenue-specific sequences in

207 ransmitted infection caused by the bacterium Treponema pallidum (subsp.

208 Although the three Treponema pallidum subspecies (T. pallidum subsp. pallid

209 Treponema pallidum subspecies pallidum (Nichols) chromos

210 cy of 18 antibiotics from several classes on Treponema pallidum subspecies pallidum (T pallidum), the

211 The tprK gene sequence of Treponema pallidum subspecies pallidum (T. pallidum) is

212 tted infection (STI) caused by the bacterium Treponema pallidum subspecies pallidum (TP).

213 We aimed to explore Treponema pallidum subspecies pallidum (TPA) molecular e

214 s a sexually transmitted infection caused by Treponema pallidum subspecies pallidum and may lead to s

215 thogen-related oral spirochetes (PROS, using Treponema pallidum subspecies pallidum monoclonal antibo

216 Syphilis, caused by Treponema pallidum subspecies pallidum, remains a signif

217 ntigen, designated Tp92, was identified from Treponema pallidum subspecies pallidum.

218 ly transmitted bacterial infection caused by Treponema pallidum subspecies pallidum.

219 Haemophilus ducreyi (HD) and Treponema pallidum subspecies pertenue (TP) are major ca

220 Yaws, caused by Treponema pallidum subspecies pertenue and diagnosed by

221 Treponema pallidum subspecies pertenue causes yaws.

222 mergence of resistance to macrolides against Treponema pallidum subspecies pertenue was seen.

223 disease (Borrelia burgdorferi) and syphilis (Treponema pallidum) swim through viscous fluids, such as

224 multaneously for multiple antigens of HIV-1, Treponema pallidum (syphilis), and hepatitis C virus (HC

225 eisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum (syphilis), herpes simplex virus 2, a

226 In Treponema pallidum (T. pallidum), the causative agent of

227 purified outer membrane vesicles (OMV) from Treponema pallidum (T.p.) could elicit Abs capable of ki

228 ns are caused by a family of closely related Treponema pallidum that give rise to the diseases yaws,

229 s is a chronic bacterial infection caused by Treponema pallidum that is endemic in low-income countri

230 Treponema pallidum, the bacterial agent of syphilis, can

231 Treponema pallidum, the bacterial agent of syphilis, is

232 Here we tested the effect of 405 nm light on Treponema pallidum, the bacterium that causes syphilis.

233 mography (cryo-ET) was utilized to visualize Treponema pallidum, the causative agent of syphilis, at

234 Treponema pallidum, the causative agent of syphilis, is

235 Tp0655 of Treponema pallidum, the causative agent of syphilis, is

236 Genome sequence analysis of Treponema pallidum, the causative agent of syphilis, sug

237 Treponema pallidum, the causative agent of venereal syph

238 rformed, targeting Chlamydia trachomatis and Treponema pallidum, the causative agents of Chlamydia an

239 Insights into the genomic adaptive traits of Treponema pallidum, the causative bacterium of syphilis,

240 Similarly, Treponema pallidum, the cause of syphilis, has remained

241 In the causative agent of syphilis, Treponema pallidum, the gene encoding 3-phosphoglycerate

242 The outer membrane of Treponema pallidum, the non-cultivable agent of venereal

243 of the 32-kDa membrane lipoprotein (Tp32) of Treponema pallidum, the syphilis bacterium.

244 The ability of Treponema pallidum, the syphilis spirochete to colonize

245 The finding that Treponema pallidum, the syphilis spirochete, contains 12

246 examine the native cellular organization of Treponema pallidum, the syphilis spirochete.

247 est for the detection of human antibodies to Treponema pallidum." The Syphilis Health Check is the on

248 In Treponema pallidum, this protein (TatT) is a water-solub

249 in this cluster are most similar to those of Treponema pallidum (Tp) and Bacillus subtilis (Bs).

250 reading frame (cheX) that is homologous with Treponema pallidum (Tp) and Borrelia burgdorferi (Bb) ch

251 dy, we found that in Tanzania infection with Treponema pallidum (TP) subsp. pertenue (TPE) is present

252 DFM) and polymerase chain reaction (PCR) for Treponema pallidum (TP), and by PCR for Haemophilus ducr

253 ittle is known about the mechanisms by which Treponema pallidum (Tp), the causative agent of syphilis

254 nd composition of the outer membrane (OM) of Treponema pallidum (Tp), the noncultivable agent of vene

255 in reaction (PCR) targeting the polA gene of Treponema pallidum (TP-PCR), we tested the following stu

256 A 38-kDa lipoprotein of Treponema pallidum (Tp38) was predicted to be a periplas

257 he antigenicity of the 15-kDa lipoprotein of Treponema pallidum (Tpp15 or TpN15) was comprehensively

258 Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidu

259 Research-use-only Treponema pallidum transcription-mediated amplification

260 The Treponema pallidum tro operon encodes an ABC transporter

261 logy to most of the previously characterized Treponema pallidum tro operon.

262 We previously demonstrated that Treponema pallidum TroA is a periplasmic metal-binding p

263 ith sequence similarity at its C terminus to Treponema pallidum TroR.

264 The tprK gene in Treponema pallidum undergoes antigenic variation.

265 The complete genome sequence of Treponema pallidum was determined and shown to be 1,138,

266 A serum sample containing antibody against Treponema pallidum was reported as positive by 70% of th

267 A molecular-based subtyping system for Treponema pallidum was used during an investigation of i

268 d-type fliG genes from T. denticola and from Treponema pallidum were cloned into this expression plas

269 882 of the 1,039 proteins in the proteome of Treponema pallidum were examined.

270 vestigated the interaction of the spirochete Treponema pallidum with the ECM component laminin.