ライフサイエンスコーパス: UDP

1 UDP and UDP-glucose activate the P2Y14 receptor (P2Y14R)

2 UDP exerted a similar effect, but higher concentrations

3 UDP-3-O-((R)-3-hydroxymyristoyl)-N-glucosamine deacetyla

4 UDP-4-N3-GlcNAc served as a chain termination substrate

5 UDP-4FGlcNAc was transferred onto an acceptor by Pastuer

6 UDP-G decreased the reductive capacity of nondiabetic hu

7 UDP-G modulated glucose-induced proliferation of INS-1 c

8 UDP-G on GSIS suppression was associated with suppressio

9 UDP-galactopyranose mutase (UGM) catalyzes the conversio

10 UDP-GlcNAc is one such metabolite that acts as a substra

11 UDP-GlcNAc is the donor substrate used in multiple glyco

12 UDP-glucose 4-epimerase (GalE) from Bifidobacterium long

13 UDP-glucose pyrophosphorylase (UGP) alternatively makes

14 UDP-glucose:glycoprotein glucosyltransferase (UGGT) 1 an

15 UDP-glucuronic acid (UDP-GlcA) is the precursor of many

16 UDP-glucuronic acid is converted to UDP-galacturonic aci

17 UDP-glycosyltransferase (UGT) plays a major role in the

18 UDP-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (Lp

19 UDP-xylose (UDP-Xyl) is the Xyl donor used in the synthe

20 ction was hypothesized to involve a family 1 UDP-sugar dependent glycosyltransferase (UGT) to facilit

21 RHM1 encodes a UDP-L-rhamnose synthase, and rhm1 mutations affect synth

22 s D and D' contain an intact gene encoding a UDP-galactose epimerase (galE1) and a truncated remnant

23 covalent addition of the sugar moiety from a UDP-sugar cofactor to relatively low-molecular weight li

24 recently shown, unexpectedly, to occur in a UDP-GlcNAc-dependent fashion within the transferase acti

25 e found that the C-terminal WbbY domain is a UDP-Galp-dependent GT-A galactosyltransferase adding bet

26 SVEN_3027 is a UDP-glucose pyrophosphorylase, SVEN_3972 is an unusual I

27 rabidopsis (Arabidopsis thaliana) CSLD3 is a UDP-glucose-dependent beta-1,4-glucan synthase that form

28 viridae, for example, are known to produce a UDP-glycosyltransferase (UGT) that negatively regulates

29 transferase and noted that WbmW represents a UDP-Galf-dependent enzyme and that both are GT-A members

30 t Pel-dependent biofilm formation requires a UDP-GlcNAc C4-epimerase that generates the UDP-GalNAc pr

31 ferase motif with alanine residues abolished UDP-GlcNAc binding and lymphostatin activity, although o

32 UDP-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (LpxA) catalyzes the first s

33 nds uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) but not UDP-glucose (UDP-Glc).

34 the HBP metabolite UDP-N-acetylglucosamine (UDP-GlcNAc) to CRPC-like cells significantly decreases c

35 of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a substrate for cellular glycosyltransferas

36 ith the cosubstrate UDP-N-acetylglucosamine (UDP-GlcNAc),O-linked-GlcNAc transferase (OGT) catalyzes

37 ase uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

38 ize uridine diphosphate N-acetylglucosamine (UDP-GlcNAc).

39 the UDP-N-acetyl-d-galactosaminuronic acid (UDP-GalNAcA) biosynthesis genes, gna-gne2, as being crit

40 re it is converted to UDP-galacturonic acid (UDP-GalA), UDP-arabinose, and UDP-xylose.

41 UDP-glucuronic acid (UDP-GlcA) is the precursor of many plant cell wall polys

42 Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employed as the cofactor by

43 transfer of the sugar moiety from activated UDP-sugars to various acceptors.

44 xpression did not respond to P2Y14 R agonist UDP-glucose (UDP-Glu) while hCPCs with higher P2Y14 R ex

45 Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employe

46 pe N-glycan branching was impaired, although UDP-GlcNAc transport into Golgi vesicles was not decreas

47 -4-fluoro-N-acetylglucosamine (4FGlcNAc) and UDP-4-deoxy-4-fluoro-N-acetylgalactosamine (4FGalNAc), w

48 s and uses cytosolic UDP-glucuronic acid and UDP-GlcNAc as substrates.

49 ilding blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as well as hyaluronic acid syn

50 cturonic acid (UDP-GalA), UDP-arabinose, and UDP-xylose.

51 s, 2-oxoglutarate-dependent dioxygenases and UDP-dependent glycosyltransferases potentially involved

52 ors activated by adenosine 5-diphosphate and UDP-sugars, respectively-were upregulated after allergen

53 uridine diphosphate (UDP) into fructose and UDP-glucose, is a key enzyme in sucrose metabolism in hi

54 We show that PGE2-G and UDP are both agonists at P2Y6, but they activate the rec

55 , or bi-functional, synthesising UDP-Gal and UDP-galactosamine (UDP-GalNAc).

56 zation reactions of UDP-Gal into UDP-Glc and UDP-GalNAc into UDP-GlcNAc with the same level of activi

57 s in the complex structures with UDP-Glc and UDP-GlcNAc.

58 calized protein that transports UDP-GlcA and UDP-GalA in vitro.

59 dified nucleotide sugars UDP-4-N3-GlcNAc and UDP-4-N3-GalNAc were chemically synthesized for the firs

60 zes the epimerization between UDP-GlcNAc and UDP-GalNAc.

61 on is the metabolic source of UDP-GlcNGc and UDP-GalNGc and the latter allows an unexpectedly selecti

62 ral other enzymes can use both UDP-GlcUA and UDP-glucose (UDP-Glc), leading to the formation of glucu

63 eriod counteracted the effect of glucose and UDP-G.

64 creased in the presence of 20 mm glucose and UDP-G.

65 -P, as well as the levels of UDP-glucose and UDP-galactose, the nucleotide sugars that are required f

66 aining cell wall precursors, UDP-Glucose and UDP-N-acetylglucosamine are efficiently used to initiate

67 rm from C24 can utilize both UDP-glucose and UDP-xylose but with a higher affinity to the glucose don

68 nsferase (UGT91L1) that uses isoorientin and UDP-rhamnose as substrates and converts them to rhamnosy

69 on of ATPase, cation transporter, kinase and UDP-glycosyltransferases genes.

70 ons, are located within the Golgi lumen, and UDP-Arap, synthesized within the Golgi, is not their pre

71 including cytochrome P450 monooxygenases and UDP-glycosyltransferases, was shared between both treatm

72 We show that the affinity to NAD+ and UDP-containing factors during initiation is much lower t

73 ta provide intriguing evidence for P2Y14 and UDP-G's role in the regulation of pancreatic beta-cell f

74 e (ADPG), kaempferol and UDPG, quercetin and UDP-galactose, isoliquiritigenin and UDPG, and luteolin

75 e identify an interaction between TAPBPR and UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1), a

76 UDP and UDP-glucose activate the P2Y14 receptor (P2Y14R) to modu

77 redominant Ara form found in plants is Araf, UDP-Arap must exit the Golgi to be interconverted into U

78 losed the following: (i) all variants act as UDP-GlcNAc/UMP antiporters; (ii) conservative substituti

79 ate a LC-MS method that assesses HBP flux as UDP-GlcNAc ((13)C)-molar percent enrichment (MPE) and co

80 in the form of UDP-GlcNAc, and galactose, as UDP-Gal, are delivered into the Golgi apparatus by SLC35

81 nction of these NSTs confirmed their role as UDP-Araf transporters in vivo.

82 ar, we observed a strong correlation between UDP-Glc concentration and the development of AKI in card

83 hat PelX catalyzes the epimerization between UDP-GlcNAc and UDP-GalNAc.

84 T1R antagonists during sensitization blocked UDP-elicited potentiation of IL-12p40 production by macr

85 showed that the concomitant binding of both UDP-MurNAc-pentapeptide-DNS and C35-P to the enzyme is r

86 GT2B7 and several other enzymes can use both UDP-GlcUA and UDP-glucose (UDP-Glc), leading to the form

87 r, and the isoform from C24 can utilize both UDP-glucose and UDP-xylose but with a higher affinity to

88 lex with UDP:Mg(2+) and in complex with both UDP:Mg(2+) and a glycan acceptor, lacto-N-neotetraose.

89 ck of the phosphate moiety of C35-P on bound UDP-MurNAc-pentapeptide.

90 Golgi to be interconverted into UDP-Araf by UDP-Ara mutases that are located outside on the cytosoli

91 Glycosylated metabolites generated by UDP-dependent glycosyltransferases (UGTs) play critical

92 etabolized solely through glucuronidation by UDP-glucuronosyltransferase (UGT) 1A1, it is now known t

93 Dose-dependent activation of P2Y14 by UDP-G suppressed glucose-stimulated insulin secretion (G

94 In SLC35A3-knockout HEK293T cells, UDP-GlcNAc transport was significantly decreased but not

95 them in vitro in the presence of acetyl-CoA, UDP- N-acetylglucosamine, NADPH, and ATP, we have develo

96 precursor has a pyranose ring configuration (UDP-Arap).

97 Subsequent C5aR1 activation controlled UDP-glucose ceramide glucosyltransferase production, the

98 n UDP-rhamnose synthase (RHS1) that converts UDP-glucose into UDP-l-rhamnose.

99 UGDH encodes an oxidoreductase that converts UDP-glucose to UDP-glucuronic acid, a key component of s

100 usly shown to encode an enzyme that converts UDP-glucuronic acid to UDP-xylose for capsule biosynthes

101 In complex with the cosubstrate UDP-N-acetylglucosamine (UDP-GlcNAc),O-linked-GlcNAc tra

102 e metabolism, leading to increased cytosolic UDP sugars, and induces abnormal intracellular hyalurona

103 involved in HA synthesis and uses cytosolic UDP-glucuronic acid and UDP-GlcNAc as substrates.

104 by fluorescence enhancement using dansylated UDP-MurNAc-pentapeptide and heptaprenyl phosphate (C35-P

105 /specificity effector-pairs bound (CDP/dATP, UDP/dATP, ADP/dGTP, GDP/TTP) that reveal the conformatio

106 NAc-transferase (MGAT1) and GSLs by deleting UDP-glucose ceramide glucosyltransferase (UGCG).

107 ty of SLC35A2 has been clearly demonstrated, UDP-GlcNAc delivery by SLC35A3 is not fully understood.

108 nversion of sucrose and uridine diphosphate (UDP) into fructose and UDP-glucose, is a key enzyme in s

109 Uridine diphosphate (UDP)-activated purinergic receptor P2Y(6) (P2Y(6)R) play

110 osylations catalyzed by uridine diphosphate (UDP)-dependent glucosyltransferases.

111 nucleotide-sugar donor uridine diphosphate (UDP)-GalNAzMe from a sugar-1-phosphate precursor.

112 Unnatural uridine diphosphate (UDP)-sugar donors, UDP-4-deoxy-4-fluoro-N-acetylglucosam

113 ural uridine diphosphate (UDP)-sugar donors, UDP-4-deoxy-4-fluoro-N-acetylglucosamine (4FGlcNAc) and

114 GALE encodes UDP-galactose-4-epimerase, an enzyme of galactose metabo

115 epression of the key GSL biosynthetic enzyme UDP-glucose ceramide glucosyltransferase (UGCG).

116 The Golgi enzyme UDP-GlcNAc:lysosomal enzymeN-acetylglucosamine-1-phospho

117 (UDP-Galf), which is generated by the enzyme UDP-galactopyranose mutase (UGM or Glf).

118 n alter the NAD(+)/NADH ratio via the enzyme UDP-glucose dehydrogenase, which oxidizes the alcohol gr

119 address this knowledge gap, here we examined UDP-galactose 4'-epimerase (GALE), which interconverts t

120 and transferase-encoding genes, for example UDP-glucoronosyltransferase and Serine-glyoxylate transf

121 Alveolar macrophages express UDP-specific P2Y6 receptors that can be blocked by off-t

122 Y14 R), a crucial detector for extracellular UDP-sugars released during injury/stress.

123 new cap structures in humans and mice (FAD, UDP-Glc, UDP-GlcNAc, and m7Gpppm6A), cell- and tissue-sp

124 2,2,7GpppG-and 5 'metabolite' caps-NAD, FAD, UDP-Glc, UDP-GlcNAc, and dpCoA.

125 A cis-QTL for UDP-glucose pyrophosphorylase activity in the UGP1 promo

126 roup E which has a synthetic requirement for UDP-GalNAc.

127 way (HBP) branches from glycolysis and forms UDP-GlcNAc, the moiety for O-linked beta-GlcNAc (O-GlcNA

128 aliana transcriptomic data, identifying four UDP-dependent glycosyltransferase (UGT) genes as wound-i

129 ase (MGD1) which adds to it a galactose from UDP-Gal.

130 cts catalyzed transfer of [(3)H]glucose from UDP-[(3)H]glucose to the trisaccharide form of Skp1 in a

131 74F1 and UGT74F2) that transfer glucose from UDP-glucose to SA.

132 of the fungal cell wall, is synthesized from UDP-GlcNAc produced in the hexosamine biosynthetic pathw

133 t14 (also referred to as Gpi3) of the fungal UDP-glycosyltransferase, the first step in GPI biosynthe

134 nverted to UDP-galacturonic acid (UDP-GalA), UDP-arabinose, and UDP-xylose.

135 dine 5'-diphosphate-alpha-d-galactofuranose (UDP-Galf), which is generated by the enzyme UDP-galactop

136 lyzes the conversion of UDP-galactofuranose (UDP-Galf) to UDP-galactopyranose (UDP-Galp) and is an im

137 ofuranose (UDP-Galf) to UDP-galactopyranose (UDP-Galp) and is an important virulence factor.

138 synthesising UDP-Gal and UDP-galactosamine (UDP-GalNAc).

139 ansferase and uridine diphosphate galactose (UDP-Gal) for global and site-specific analysis of protei

140 mono-functional, synthesising UDP-galactose (UDP-Gal), or bi-functional, synthesising UDP-Gal and UDP

141 Leu) revealed that SLC35D1 acts as a general UDP-sugar transporter and that the p.(Pro133Leu) mutatio

142 G-and 5 'metabolite' caps-NAD, FAD, UDP-Glc, UDP-GlcNAc, and dpCoA.

143 structures in humans and mice (FAD, UDP-Glc, UDP-GlcNAc, and m7Gpppm6A), cell- and tissue-specific va

144 uridine diphosphate N-acetyl-D-glucosamine (UDP-GlcNAc) in human prostate cancer LnCaP-LN3 cells, we

145 ed the relative contribution of UDP-glucose (UDP-G), a P2Y14-specific agonist, in the regulation of i

146 on of the P2Y14 receptor ligand UDP-glucose (UDP-Glc) was higher in urine samples from intensive care

147 ymes can use both UDP-GlcUA and UDP-glucose (UDP-Glc), leading to the formation of glucuronide and gl

148 lucosamine (UDP-GlcNAc) but not UDP-glucose (UDP-Glc).

149 not respond to P2Y14 R agonist UDP-glucose (UDP-Glu) while hCPCs with higher P2Y14 R expression show

150 GNE (UDP-GlcNAc 2-epimerase/ManNAc kinase) myopathy is a rare

151 s that synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as wel

152 The data indicate that lymphostatin has UDP-sugar binding potential that is critical for activit

153 Enzymes of the human UDP-glycosyltransferase (UGT) superfamily typically cata

154 titutions (E47D, E47Q, K50R, or K50H) impair UDP-GlcNAc uptake; and (iii) substitutions of Glu-47 and

155 onjugates than WT cells, indicating impaired UDP-GlcNAc transport activity of these two variants.

156 s end, we further show that the galactose in UDP-galactose is incorporated into mature, de novo glyca

157 served a concentration-dependent increase in UDP-GlcNAc levels and MPE, with the latter reaching a pl

158 Taken together, these findings indicate UDP-sugar balance is a key modifier of neurological outc

159 action in CHS, rs686237, strongly influenced UDP-Gal:betaGlcNAc beta-1,4-galactosyltransferase, polyp

160 yzes epimerization reactions of UDP-Gal into UDP-Glc and UDP-GalNAc into UDP-GlcNAc with the same lev

161 of UDP-Gal into UDP-Glc and UDP-GalNAc into UDP-GlcNAc with the same level of activity that is requi

162 nthase (RHS1) that converts UDP-glucose into UDP-l-rhamnose.

163 ust exit the Golgi to be interconverted into UDP-Araf by UDP-Ara mutases that are located outside on

164 rt to its ability to sequester intracellular UDP-glucuronic acid and inhibition of hyaluronan synthas

165 ere their folding is surveyed by the 170-kDa UDP-glucose:glycoprotein glucosyltransferase (UGGT).

166 ransferase C1GalT1 with isotopically labeled UDP-Gal((13)C(6)), to tag and convert Tn to Gal((13)C(6)

167 Crigler-Najjar syndrome model animal lacking UDP-glucuronosyltransferase (UGT1A1), was used as recipi

168 e concentration of the P2Y14 receptor ligand UDP-glucose (UDP-Glc) was higher in urine samples from i

169 The EBD binds to the suppressor ligand UDP-N-acetyl-beta-d-muramyl-l-Ala-gamma-d-Glu-meso-DAP-d

170 racterization of a family of Golgi-localized UDP-Araf transporters in Arabidopsis The application of

171 To identify the Golgi-localized UDP-GlcA transporter, we screened Arabidopsis thaliana m

172 pyrophosphorylase (UGP) alternatively makes UDP-galactose from uridine triphosphate and galactose-1-

173 Mechanistically, UDP-Glu stimulation enhanced the activation of canonical

174 l-3-O-glucose (D3G), by secondary metabolism UDP-glucosyltransferases (UGTs).

175 Strikingly, addition of the HBP metabolite UDP-N-acetylglucosamine (UDP-GlcNAc) to CRPC-like cells

176 Two montbretia UDP-dependent glycosyltransferases (UGTs), CcUGT1 and Cc

177 residues involved in the activity of a mouse UDP-GlcNAc transporter, murine solute carrier family 35

178 Sm1 encodes a multidomain UDP-rhamnose synthase (RHS1) that converts UDP-glucose i

179 s: NAD(+)/UDP, NAD(+)/UDP-GlcNAc, and NAD(+)/UDP-Glc.

180 bGalE in three ternary complex forms: NAD(+)/UDP, NAD(+)/UDP-GlcNAc, and NAD(+)/UDP-Glc.

181 ee ternary complex forms: NAD(+)/UDP, NAD(+)/UDP-GlcNAc, and NAD(+)/UDP-Glc.

182 ate-N-acetylglucosamine (UDP-GlcNAc) but not UDP-glucose (UDP-Glc).

183 the pentose phosphate pathway, nucleobases, UDP-sugars, glycogen, lipids, and proteins in mouse tiss

184 monstrate that H3 binds the sugar nucleotide UDP-glucose, as do glycosyltransferases.

185 Mutations in UXS1 lead to accumulation of UDP-glucuronic acid and alterations in nucleotide metabo

186 f metabolism because the binding affinity of UDP-GlcUA is higher than that of UDP-Glc.

187 responsible for the preferential binding of UDP-GlcUA.

188 MUR4 also contribute to the biosynthesis of UDP-Ara and are critical for root elongation.

189 e, which is required for the biosynthesis of UDP-Arap in Arabidopsis, led to reduced root elongation

190 The biosynthesis of UDP-Arap mainly occurs via the epimerization of UDP-xylo

191 se enzyme, PglD, involved in biosynthesis of UDP-diNAcBac in Campylobacter jejuni.

192 d T cells contained higher concentrations of UDP-GlcNAc and increased intracellular protein O-GlcNAcy

193 we investigated the relative contribution of UDP-glucose (UDP-G), a P2Y14-specific agonist, in the re

194 ose mutase (UGM) catalyzes the conversion of UDP-galactofuranose (UDP-Galf) to UDP-galactopyranose (U

195 We found that depletion of UDP-glucuronic acid altered the expression of PPAR-gamma

196 GSIS and prevented the inhibitory effect of UDP-G on GSIS.

197 -Arap mainly occurs via the epimerization of UDP-xylose (UDP-Xyl) in the Golgi lumen.

198 us result in part from delayed expression of UDP-glucuronosyltransferase 1A1 (UGT1A1) and the inabili

199 cosylation is initiated by a large family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

200 GlcNAc, in the form of UDP-GlcNAc, and galactose, as UDP-Gal, are delivered int

201 ty from acetyl-CoA to the C-4 amino group of UDP-d-viosamine.

202 l carrier protein (ACP) to the 3-OH group of UDP-GlcNAc.

203 t Gram-negative pathogens, the hydrolysis of UDP-2,3-diacylglucosamine to generate lipid X in lipid A

204 r, this study demonstrates the importance of UDP-GalNAcA in the pathobiology of A. baumannii.

205 nst the UTP receptor P2Y2, and inhibitors of UDP receptors P2Y6 and P2Y14, indicated that the respons

206 two reversible reactions: interconversion of UDP-galactose with UDP-glucose and interconversion of UD

207 tose with UDP-glucose and interconversion of UDP-N-acetylgalactosamine with UDP-N-acetylglucosamine.

208 farinae (Df) sharply increased the levels of UDP detected in bronchoalveolar lavage fluid of mice.

209 ga Prymnesium parvum, we show that levels of UDP- and TDP-activated l-Rha differ significantly betwee

210 GNE deficiency may affect levels of UDP-GlcNAc, a key metabolite in the nutrient-sensing hex

211 s of galactose-1-P, as well as the levels of UDP-glucose and UDP-galactose, the nucleotide sugars tha

212 atic activity, resulting in higher levels of UDP-N-acetylglucosamine biosynthesis and protein O-GlcNA

213 RNAs specifically reacted with the lysine of UDP-MurNAc-pentapeptide, a peptidoglycan precursor used

214 c transporter and/or different mechanisms of UDP-GlcNAc transport into the Golgi apparatus may exist.

215 affected the binding of fructose, but not of UDP.

216 (bGalE) catalyzes epimerization reactions of UDP-Gal into UDP-Glc and UDP-GalNAc into UDP-GlcNAc with

217 eu5Gc degradation is the metabolic source of UDP-GlcNGc and UDP-GalNGc and the latter allows an unexp

218 ucose and glutamine for de novo synthesis of UDP-GlcNAc, a sugar-nucleotide that inhibits receptor en

219 The synthesis of UDP-glucuronic acid can alter the NAD(+)/NADH ratio via

220 affinity of UDP-GlcUA is higher than that of UDP-Glc.

221 Thus, the transport of UDP-Araf into the Golgi is a prerequisite.

222 , S-adenosylmethionine, carbamoyl phosphate, UDP-glucose, and Delta(2)-isopentenyl-PP play similar ro

223 ombinantly produced protein Sv0189 possessed UDP-glycosyltransferase activity.

224 t depletion of the hyaluronic acid precursor UDP-glucuronic acid is sufficient to inhibit several mes

225 MU and without depletion of the HA precursor UDP-glucuronic acid (GlcUA).

226 incorporation of mature cell wall precursor, UDP-MurNAc-pentapeptide, is inhibited by region 3.2 of s

227 ant uridine-containing cell wall precursors, UDP-Glucose and UDP-N-acetylglucosamine are efficiently

228 suggest that SLC35A3 may not be the primary UDP-GlcNAc transporter and/or different mechanisms of UD

229 ne biosynthetic pathway (HBSP) that produces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine

230 extracellular UTP or its breakdown products UDP and UMP act as mediators for hyaluronan synthase (HA

231 d VKORC1v2- and calnexin-associated proteins UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) a

232 ORC1v2 interact with calnexin cycle proteins UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1),

233 sis and glutaminolysis co-operatively reduce UDP-GlcNAc biosynthesis and N-glycan branching in mouse

234 The structure revealed that PelX resembles UDP-GlcNAc C4-epimerases.

235 eotide uridine 5'-diphospho-beta-l-rhamnose (UDP-beta-l-Rha) or thymidine 5'-diphospho-beta-l-rhamnos

236 Subsequently, UDP-Araf must be transported back into the lumen.

237 l aligned near the entrance of the substrate UDP-glucose into the active site.

238 lNAc glycans in nuclei: the donor substrate (UDP-GalNAc), nuclear polypeptide GalNAc -transferase act

239 but is distinct from, its natural substrate, UDP-MurNAc-pentapeptide.

240 atural chemically modified nucleotide sugars UDP-4-N3-GlcNAc and UDP-4-N3-GalNAc were chemically synt

241 se (UDP-Gal), or bi-functional, synthesising UDP-Gal and UDP-galactosamine (UDP-GalNAc).

242 n to be either mono-functional, synthesising UDP-galactose (UDP-Gal), or bi-functional, synthesising

243 ationally predicted putative miR-185 targets UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltran

244 The UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH i

245 The UDP-glucuronosyltransferase (UGT) family of enzymes is i

246 The UDP-glycosyltransferases, CcUGT4 and CcUGT5, catalyze co

247 (GSIS) and knockdown of P2Y14 abolished the UDP-G effect.

248 However, although the UDP-Gal transporting activity of SLC35A2 has been clearl

249 imilar approaches, we identified WbmV as the UDP-GlcNAc transferase and noted that WbmW represents a

250 nduction of cytoprotective genes such as the UDP-glucuronosyltransferases (UGTs).

251 hat coordinates a Mg(2+) ion for binding the UDP-GlcNAc sugar donor.

252 hase, a key regulatory enzyme encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene.

253 nduced activation of a K(+) conductance, the UDP-stimulated phagocytic activity, and the ATP-dependen

254 on of two androgen-inactivating enzymes, the UDP-glucuronosyltransferases UGT2B15 and UGT2B17, was as

255 a UDP-GlcNAc C4-epimerase that generates the UDP-GalNAc precursors required by the Pel synthase machi

256 genous expression systems, we identified the UDP receptor P2Y6 as the specific target of PGE2-G.

257 We previously identified the UDP-N-acetyl-d-galactosaminuronic acid (UDP-GalNAcA) bio

258 Our study identifies the UDP-Glc/P2Y14 receptor axis as a potential target for th

259 ew insights into the enzymes involved in the UDP-Ara biosynthesis in plants.

260 s thaliana) lines carrying insertions in the UDP-Glc:sterol glucosyltransferase genes, UGT80A2 and UG

261 Modeling of the UDP-GlcNAc donor supports a direct displacement invertin

262 Here, we report the 3D structure of the UDP-glucosyltransferase UGT76G1, including a complex of

263 al high-resolution crystal structures of the UDP-glucuronic acid epimerase from Bacillus cereus The g

264 s study unveil novel biological roles of the UDP-sugar receptor P2Y14 in hCPCs and suggest purinergic

265 ween UGT89A2 from Col-0 and C24 reversed the UDP-sugar preferences, indicating that residue 153 plays

266 We considered that the UDP-diacylglucosamine pyrophosphohydrolase LpxH could be

267 t shares twin Rossmann-like domains with the UDP-glucose-specific OtsA from Escherichia coli However,

268 sed in uuat1 These results suggest that this UDP-GlcA transporter plays a key role defining the seed

269 enzyme that converts UDP-glucuronic acid to UDP-xylose for capsule biosynthesis, but not known to pl

270 he Golgi apparatus, where it is converted to UDP-galacturonic acid (UDP-GalA), UDP-arabinose, and UDP

271 UDP-glucuronic acid is converted to UDP-galacturonic acid en route to a variety of sugar-con

272 version of UDP-galactofuranose (UDP-Galf) to UDP-galactopyranose (UDP-Galp) and is an important virul

273 oxidoreductase that converts UDP-glucose to UDP-glucuronic acid, a key component of specific proteog

274 Genes linked to UDP-sugar biosynthesis and cellulose synthesis were also

275 showed enhanced proliferation in response to UDP-Glu stimulation.

276 lyzes the ATP-dependent conversion of UMP to UDP in vitro with properties characteristic of known ess

277 GT89A2 from Col-0 is highly selective toward UDP-xylose as the sugar donor, and the isoform from C24

278 prenyl transfers (IPP), glucosyl transfers (UDP-glucose), and electron and ADP-ribosyl transfers (NA

279 orter (NST) family can efficiently transport UDP-Araf in vitro.

280 es a Golgi-localized protein that transports UDP-GlcA and UDP-GalA in vitro.

281 the subsequent 4-HPAA reductase and tyrosol:UDP-glucose 8-O-glucosyltransferase, respectively, to co

282 lly characterize nine ripening-related UGTs (UDP-glucosyltransferases) in Fragaria that function in t

283 The resulting unnatural UDP-sugar donors were then tested as substrates in glyco

284 These unnatural UDP sugar products were then tested for incorporation in

285 ion is triggered by redistribution of unused UDP-GlcNAc from the medial to trans-Golgi via inter-cist

286 substrate rather than the more commonly used UDP-glucose.

287 Using UDP-glucose as sugar donor, we show that purified LtpM n

288 ose-containing glycans are synthesized using UDP-apiose as the donor.

289 inly through P2Y2 and to a lesser extent via UDP receptors.

290 apoptosis, which was further amplified when UDP-G was present.

291 conversion of UDP-N-acetylgalactosamine with UDP-N-acetylglucosamine.

292 e structures of human B3GNT2 in complex with UDP:Mg(2+) and in complex with both UDP:Mg(2+) and a gly

293 tions: interconversion of UDP-galactose with UDP-glucose and interconversion of UDP-N-acetylgalactosa

294 terminal domain, specifically interacts with UDP-GlcUA, whereby the side chain of Arg259 H-bonds and

295 ciency of initiation with NAD+, but not with UDP-containing factors, is affected by amino acids of th

296 6G1, including a complex of the protein with UDP and rebaudioside A bound in the active site.

297 l binding interactions of a UGT protein with UDP-sugar cofactors.

298 conformations in the complex structures with UDP-Glc and UDP-GlcNAc.

299 occurs via the epimerization of UDP-xylose (UDP-Xyl) in the Golgi lumen.

300 UDP-xylose (UDP-Xyl) is the Xyl donor used in the synthesis of major