ライフサイエンスコーパス: Wiskott-Aldrich syndrome protein

1 actin-nucleating machine activated by WASp (Wiskott Aldrich syndrome protein).

2 n with the nucleation-promoting factor Wasp (Wiskott-Aldrich syndrome protein).

3 fining mechanisms that control activation of Wiskott-Aldrich syndrome protein.

4 se 1, Grb2-associated protein 2 (Grap2), and Wiskott-Aldrich syndrome protein.

5 ft microdomain along with Arp2/3 complex and Wiskott-Aldrich syndrome protein.

6 ing edges of lamellipodia, Arp3 and neuronal Wiskott-Aldrich syndrome protein.

7 Cdc42 using the GTPase-binding domain of the Wiskott-Aldrich syndrome protein.

8 adhesion kinase, Rho GTPase Rac1, and neural Wiskott-Aldrich syndrome protein.

9 e cytoskeleton by binding and activating the Wiskott-Aldrich syndrome protein.

10 suring vector copy numbers and expression of Wiskott-Aldrich syndrome protein.

11 ngagement increases actin polymerization and Wiskott-Aldrich syndrome protein activation in a Btk-dep

12 achment but inhibits ingestion by decreasing Wiskott-Aldrich syndrome protein activation, and hence a

13 as the levels of F-actin and phosphorylated Wiskott Aldrich syndrome protein, an actin nucleation pr

14 r binding to the SH3 domains with the neural Wiskott-Aldrich Syndrome protein, an actin filament nucl

15 exists in a macromolecular complex with the Wiskott-Aldrich syndrome protein, an actin nucleation-pr

16 rmore, syndapin I associates with the neural Wiskott-Aldrich syndrome protein, an actin-depolymerizin

17 Fusion of macrophages deficient in Wiskott-Aldrich syndrome protein and Cdc42, key molecule

18 e Cdc42-binding domains of the CRIB motif of Wiskott-Aldrich Syndrome protein and p21(cdc42/rac)-acti

19 contractility, independent of its effects on Wiskott-Aldrich syndrome protein and p21-activated kinas

20 lled strumpellin, is a core component of the Wiskott-Aldrich syndrome protein and SCAR homolog (WASH)

21 t complex and the endosomal Arp2/3 activator Wiskott-Aldrich syndrome protein and Scar homolog (WASH)

22 l. and Gomez and Billadeau reveal that WASH (Wiskott-Aldrich syndrome protein and SCAR homolog) activ

23 WASH (Wiskott-Aldrich Syndrome Protein and SCAR Homolog) is an

24 FAM21, which also binds retromer, within the Wiskott-Aldrich syndrome protein and SCAR homologue (WAS

25 w that the COMMD/CCDC22/CCDC93 (CCC) and the Wiskott-Aldrich syndrome protein and SCAR homologue (WAS

26 JIPs are recruited by Wiskott-Aldrich syndrome protein and scar homologue (WAS

27 Wiskott-Aldrich syndrome protein and SCAR homologue (WAS

28 The Arp2/3-activator Wiskott-Aldrich syndrome protein and Scar homologue (WAS

29 Mutation of the Wiskott-Aldrich syndrome protein and SCAR homology (WASH

30 dc42 may regulate the activation of neuronal Wiskott-Aldrich syndrome protein and the actin related p

31 ptor that replaces toca-1 to mobilize neural Wiskott-Aldrich syndrome protein and the Arp2/3 complex.

32 hat drive actin polymerization such as WASp (Wiskott-Aldrich syndrome protein) and HS1 (hematopoietic

33 mbly protein Las17 (a yeast homolog of human Wiskott-Aldrich syndrome protein) and participate in the

34 ns of increased detergent stringency Sam 68, Wiskott-Aldrich Syndrome protein, and hnRNP-K, but not C

35 owever was slower and required intact actin, Wiskott-Aldrich syndrome protein, and microtubule functi

36 kott-Aldrich syndrome protein (WASP), neural Wiskott-Aldrich syndrome protein, and WASP-interacting p

37 The Src family kinase Hck, Wiskott-Aldrich-syndrome protein, and phospholipase Cgam

38 ctin dynamics through the Nck/N-WASp (neural Wiskott-Aldrich syndrome protein)/Arp2/3 pathway is esse

39 to which we apply these ideas is that of the Wiskott-Aldrich Syndrome Proteins as activators of actin

40 belson tyrosine kinase) and N-WASP (neuronal Wiskott-Aldrich Syndrome Protein) at the cell edge witho

41 previously that the yeast orthologue of the Wiskott-Aldrich Syndrome protein, Bee1/Las17p, and the t

42 The constitutively active mutant of the Wiskott-Aldrich Syndrome protein (CA-WASp) is the cause

43 Mutations of the Wiskott-Aldrich syndrome protein can result in highly va

44 cell division cycle 42, which, together with Wiskott-Aldrich syndrome protein, coordinates F-actin re

45 for actin binding (profilin or the WH2 from Wiskott-Aldrich syndrome protein) decrease full-length I

46 Studies of Wiskott-Aldrich syndrome protein-deficient cell lines an

47 Wiskott-Aldrich syndrome protein-deficient neutrophils a

48 ition, Arp3-silenced cells expressing neural Wiskott-Aldrich syndrome protein-derived peptides that i

49 surface receptors was rapid and depended on Wiskott-Aldrich syndrome protein-driven actin polymeriza

50 ely in hematopoietic stem cells, and because Wiskott-Aldrich syndrome protein exerts a strong selecti

51 Recombinant Arc40 bound the VCA domain of Wiskott-Aldrich syndrome protein family activators at a

52 The scaffolding protein WAVE-1 (Wiskott-Aldrich syndrome protein family member 1) direct

53 et breast cancer development and metastasis, Wiskott-Aldrich syndrome protein family member 3 (Wasf3)

54 xin A1 and GDE3 from the plasma membrane via Wiskott-Aldrich syndrome protein family member 3 (WAVE3)

55 Wiskott-Aldrich syndrome protein family verprolin homolo

56 binding regions of TOCA1 and a member of the Wiskott-Aldrich syndrome protein family, N-WASP.

57 EspF(U) potently activates the host WASP (Wiskott-Aldrich syndrome protein) family of actin-nuclea

58 proteins 2/3) complex is activated by WASP (Wiskott-Aldrich syndrome protein) family proteins to nuc

59 be mediated by the protein Scar/WAVE (WASP (Wiskott-Aldrich syndrome protein)-family verprolin homol

60 regulator of actin dynamics called the WAVE (Wiskott-Aldrich syndrome protein-family verprolin homolo

61 The Wiskott-Aldrich syndrome protein-family verprolin-homolo

62 Further, CYFIP2 is part of the Wiskott-Aldrich syndrome protein-family verprolin-homolo

63 NK cell function relies on Wiskott-Aldrich syndrome protein for filamentous actin (

64 We purified native WASp (Wiskott-Aldrich Syndrome protein) from bovine thymus and

65 Wiskott-Aldrich syndrome protein gene mutations result i

66 drich syndrome is caused by mutations of the Wiskott-Aldrich syndrome protein gene, which codes for a

67 By fusing the Wiskott-Aldrich syndrome protein/GTPase-binding domain t

68 he discovery of unique functional domains of Wiskott-Aldrich syndrome protein has been instrumental i

69 ress made in dissecting the functions of the Wiskott-Aldrich syndrome protein has direct implications

70 g a proline-rich domain and an actin-binding Wiskott-Aldrich syndrome protein homology 2 (WH2) domain

71 despite having only a single G-actin-binding Wiskott-Aldrich syndrome protein Homology 2 (WH2) domain

72 length short (SALS) is a recently identified Wiskott-Aldrich syndrome protein homology 2 (WH2) domain

73 y relies on a cluster of three actin-binding Wiskott-Aldrich syndrome protein homology 2 (WH2) domain

74 autoregulatory domain (DAD) that resembles a Wiskott-Aldrich syndrome protein homology 2 (WH2) sequen

75 tant manner, bound actin monomer via a WASP (Wiskott-Aldrich syndrome protein) homology 2 domain, bou

76 variable was the presence or absence of the Wiskott-Aldrich syndrome protein in the lymphoid cells f

77 he actin regulatory protein N-WASP (neuronal Wiskott-Aldrich syndrome protein) in which the "output"

78 Wiskott-Aldrich syndrome protein-interacting protein (WI

79 s includes Wiskott-Aldrich syndrome protein, Wiskott-Aldrich syndrome protein-interacting protein, co

80 WIP, the Wiskott-Aldrich syndrome protein-interacting protein, is

81 Wiskott-Aldrich syndrome protein is a signaling molecule

82 ed to aspartate or glutamate, the binding to Wiskott-Aldrich Syndrome protein is abrogated.

83 Since Wiskott-Aldrich syndrome protein is expressed exclusivel

84 In addition, the Wiskott-Aldrich syndrome protein is required for natural

85 nucleation-promoting protein N-WASP (Neural Wiskott-Aldrich syndrome protein) is up-regulated in bre

86 toskeletal protein with sequence homology to Wiskott-Aldrich syndrome protein, is required for the fi

87 mphiphysin-RVS-domain protein Rvs167 and the Wiskott-Aldrich syndrome protein Las17 at the point of p

88 In contrast, Wiskott-Aldrich syndrome protein localized exclusively a

89 such as integrin beta1, cortactin, neuronal Wiskott-Aldrich syndrome protein, membrane type 1 metall

90 sion required actin polymerization, neuronal Wiskott-Aldrich syndrome protein, myosin II and Rho GTPa

91 stimulated phosphoprotein (VASP), and neural Wiskott Aldrich syndrome protein (N-WASP) are present at

92 study, we investigated the role of neuronal Wiskott Aldrich syndrome protein (N-WASP) in modulating

93 tein c-Abl interactor 1 (Abi1) with neuronal Wiskott-Aldrich syndrome protein (N-WASP) (an actin-regu

94 complex was necessary for cdc42 and neuronal Wiskott-Aldrich syndrome protein (N-WASP) activation, ac

95 spatial and temporal regulation of neuronal Wiskott-Aldrich syndrome protein (N-WASP) activity in li

96 localization of the actin-regulatory neural Wiskott-Aldrich syndrome protein (N-WASP) and actin-rela

97 nts in the actin regulatory protein neuronal Wiskott-Aldrich syndrome protein (N-WASP) and an SH2 dom

98 Neural Wiskott-Aldrich syndrome protein (N-WASP) and p34-Arc, a

99 474/1 leads to recruitment of Nck and neural Wiskott-Aldrich syndrome protein (N-WASP) and strong act

100 c42), the nucleation-promoting factor neural Wiskott-Aldrich syndrome protein (N-WASP) and the actin

101 Neuronal Wiskott-Aldrich syndrome protein (N-WASP) and the actin-

102 zation is mediated by activation of neuronal Wiskott-Aldrich syndrome protein (N-WASp) and the Arp (a

103 iprotein compound containing CrkII, neuronal Wiskott-Aldrich Syndrome Protein (N-WASP) and the Arp2/3

104 gulators of actin cytoskeleton dynamics, the Wiskott-Aldrich syndrome protein (N-WASP) and the Arp2/3

105 ole of the actin nucleation promoters neural Wiskott-Aldrich syndrome protein (N-WASP) and WAVE2 in c

106 and Src family tyrosine kinases, and neural Wiskott-Aldrich syndrome protein (N-WASP) but not the Ar

107 indicates that the nuclear localized neural Wiskott-Aldrich syndrome protein (N-WASP) can induce de

108 Neuronal Wiskott-Aldrich syndrome protein (N-WASP) has an essenti

109 The Neuronal Wiskott-Aldrich syndrome protein (N-WASP) has emerged as

110 we showed that S. flexneri relies on neural Wiskott-Aldrich Syndrome protein (N-WASP) in HT-29 cells

111 f hyaluronan (HA) and CD44 with the neuronal Wiskott-Aldrich syndrome protein (N-WASP) in regulating

112 f the actin-regulatory protein called neural Wiskott-Aldrich syndrome protein (N-WASP) interacting wi

113 Neuronal Wiskott-Aldrich syndrome protein (N-WASP) is a member of

114 The VCA domain of the neuronal Wiskott-Aldrich syndrome protein (N-WASP) is a potent ac

115 Co et al. now show that the neural Wiskott-Aldrich syndrome protein (N-WASP) mediates dynam

116 er suggests that the actin-regulatory neural Wiskott-Aldrich syndrome protein (N-WASP) mediates the e

117 In this study, we show neural Wiskott-Aldrich syndrome protein (N-WASP) regulates the

118 actin nucleating endocytic protein neuronal Wiskott-Aldrich syndrome protein (N-WASP) to facilitate

119 of the nucleation-promoting factor Neuronal Wiskott-Aldrich Syndrome Protein (N-WASp) to inactive, s

120 Neuronal Wiskott-Aldrich Syndrome protein (N-WASP) transmits sign

121 n activation of the Arp2/3 complex by neural Wiskott-Aldrich Syndrome protein (N-WASP) via Grb2 and N

122 I, synaptojanin, synapsin I, and the neural Wiskott-Aldrich syndrome protein (N-WASP), a stimulator

123 Neural Wiskott-Aldrich syndrome protein (N-WASP), a ubiquitous

124 -mediated EGFR signaling up-regulated neural Wiskott-Aldrich syndrome protein (N-WASP), an actin nucl

125 acted with lacrimal acinar dynamin, neuronal Wiskott-Aldrich Syndrome protein (N-WASP), and synaptoja

126 ched in actin-related protein 3 and neuronal Wiskott-Aldrich syndrome protein (N-WASP), and their ass

127 in-binding and -polymerizing proteins neural Wiskott-Aldrich syndrome protein (N-WASP), cortactin, an

128 d the actin nucleation pathway member Neural Wiskott-Aldrich syndrome protein (N-WASP), form during a

129 ockout approach to assess the role of neural Wiskott-Aldrich syndrome protein (N-WASP), the ubiquitou

130 s, we have analysed the dynamics of neuronal Wiskott-Aldrich syndrome protein (N-WASP), WASP-interact

131 We altered the function of neural Wiskott-Aldrich syndrome protein (N-WASP), which induces

132 nce microscopy, we demonstrate that neuronal Wiskott-Aldrich syndrome protein (N-WASP), which is coex

133 Here, we demonstrate that neuronal Wiskott-Aldrich syndrome protein (N-WASP), which promote

134 M. avium led to the recruitment of neuronal Wiskott-Aldrich syndrome protein (N-WASp), which was not

135 Neuronal Wiskott-Aldrich syndrome protein (N-WASP)-activated acti

136 karyotic sorting nexin 9 (SNX9) and neuronal Wiskott-Aldrich syndrome protein (N-WASP).

137 the actin polymerization catalyst, neuronal Wiskott-Aldrich syndrome protein (N-WASP).

138 nd like IcsA, YapV recruits mammalian neural Wiskott-Aldrich syndrome protein (N-WASP).

139 Nck and the actin nucleation promoter neural Wiskott-Aldrich syndrome protein (N-WASP).

140 onse to signals that locally activate neural Wiskott-Aldrich-syndrome protein (N-WASP) and the Arp2/3

141 Neural Wiskott-Aldrich syndrome protein(N-Wasp) is an actin nuc

142 ed that C. parvum activates the Cdc42/neural Wiskott-Aldrich syndrome protein network in host cells r

143 the microtubule-organizing center, F-actin, Wiskott-Aldrich syndrome protein, nor proline rich tyros

144 the actin regulatory proteins Las17p (yeast Wiskott-Aldrich syndrome protein) or Arp2/3, or deletion

145 became more tightly associated with neuronal Wiskott-Aldrich syndrome protein, promoting actin-relate

146 Neuronal Wiskott-Aldrich syndrome protein regulates TGF-beta1-med

147 WASH is an Arp2/3 activator of the Wiskott-Aldrich syndrome protein superfamily that functi

148 ASH is an endosomal protein belonging to the Wiskott-Aldrich syndrome protein superfamily that partic

149 ve studies of patients with mutations of the Wiskott-Aldrich syndrome protein unequivocally demonstra

150 The actin-modulating protein Wiskott-Aldrich syndrome protein verprolin homologous-1

151 The direct interaction of Skap2 with the Wiskott-Aldrich syndrome protein via its SH3 domain is c

152 ctin dynamics and Ag transport by activating Wiskott-Aldrich syndrome protein via Vav and phosphatidy

153 pe, a gene encoding a protein related to the Wiskott-Aldrich Syndrome protein was discovered.

154 Finally, the Wiskott-Aldrich syndrome protein was shown to play an im

155 to mutations of the X-chromosome gene WASP (Wiskott-Aldrich syndrome protein), was characterized ori

156 The actin cytoskeletal regulator Wiskott Aldrich syndrome protein (WASp) has been implica

157 ed lipid bilayers coated with purified yeast Wiskott Aldrich Syndrome Protein (WASP), an endocytic ac

158 The 70 C-terminal amino acids of Wiskott-Aldrich syndrome protein (WASp WA) activate the

159 3 complex also interacts with members of the Wiskott-Aldrich syndrome protein (WASP) [8] family - Sca

160 We have shown previously that Wiskott-Aldrich syndrome protein (WASP) activation at th

161 The Wiskott-Aldrich syndrome protein (WASP) and its homolog

162 The Wiskott-Aldrich syndrome protein (WASP) and its relative

163 The Wiskott-Aldrich syndrome protein (WASP) and neural WASP

164 The WIP C-terminal domain binds to Wiskott-Aldrich syndrome protein (WASp) and regulates it

165 ctivation, when it is able to associate with Wiskott-Aldrich syndrome protein (WASp) and the actin fi

166 Actin polymerization mediated by Wiskott-Aldrich syndrome protein (WASp) and the actin-re

167 tion by activating the pathway involving the Wiskott-Aldrich syndrome protein (WASP) and the actin-re

168 Nodule formation is dependent on Wiskott-Aldrich syndrome protein (WASp) and the ARP2/3 c

169 namics are controlled by Arp2/3 complex, the Wiskott-Aldrich syndrome protein (WASp) and the related

170 in polymerization through Arp2/3 nucleation, Wiskott-Aldrich syndrome protein (WASP) and WASP family

171 ing proteins were the actin binding proteins Wiskott-Aldrich syndrome protein (WASP) and WASP-interac

172 In T lymphocytes, the Wiskott-Aldrich Syndrome protein (WASP) and WASP-interac

173 actin polymerization in pseudopods, whereas Wiskott-Aldrich syndrome protein (WASP) assembles actin

174 s) induces localized activation of Cdc42 and Wiskott-Aldrich Syndrome protein (WASP) at the immune sy

175 the SRC homology 3 (SH3) domain and impairs Wiskott-Aldrich syndrome protein (WASP) binding, but it

176 tative model of allosteric regulation of the Wiskott-Aldrich syndrome protein (WASP) by the Rho GTPas

177 the formation of endogenous Lck-Dlgh1-Zap70-Wiskott-Aldrich syndrome protein (WASp) complexes in whi

178 w that the actin nucleation-promoting factor Wiskott-Aldrich syndrome protein (WASP) contributes to m

179 Wiskott-Aldrich syndrome protein (WASP) deficiency in mi

180 ry immune deficiency disorder resulting from Wiskott-Aldrich syndrome protein (WASp) deficiency.

181 efined by either WAS gene mutation or absent Wiskott-Aldrich syndrome protein (WASP) expression or a

182 which are caused by WAS mutations affecting Wiskott-Aldrich syndrome protein (WASp) expression or ac

183 rimary immunodeficiency caused by absence of Wiskott-Aldrich syndrome protein (WASP) expression, resu

184 The proteins of the Wiskott-Aldrich syndrome protein (WASP) family are activ

185 Members of the Wiskott-Aldrich syndrome protein (WASP) family control a

186 Members of the Wiskott-Aldrich syndrome protein (WASP) family control c

187 We recently showed that the Wiskott-Aldrich syndrome protein (WASP) family member, W

188 d by different human proteins, including the Wiskott-Aldrich syndrome protein (WASp) family members.

189 the actin cytoskeleton through activation of Wiskott-Aldrich syndrome protein (WASP) family members.

190 The binding of Wiskott-Aldrich syndrome protein (WASP) family NPFs indu

191 w that mycolactone operates by hijacking the Wiskott-Aldrich syndrome protein (WASP) family of actin-

192 WAVE proteins are members of the Wiskott-Aldrich syndrome protein (WASP) family of scaffo

193 everal recent studies have demonstrated that Wiskott-Aldrich syndrome protein (WASP) family proteins

194 esponse to upstream signals, proteins in the Wiskott-Aldrich Syndrome protein (WASP) family regulate

195 Wiskott-Aldrich syndrome protein (WASP) family verprolin

196 , and acidic (VCA) region of proteins in the Wiskott-Aldrich syndrome protein (WASp) family, Arp2/3 c

197 Members of the Wiskott-Aldrich syndrome protein (WASP) family, includin

198 in response to signals from proteins in the Wiskott-Aldrich syndrome protein (WASP) family.

199 controls actin by activating members of the Wiskott-Aldrich syndrome protein (WASP) family.

200 the actin machinery, such as members of the Wiskott-Aldrich syndrome protein (WASp) family.

201 WAS and XLT are caused by mutations of the Wiskott-Aldrich syndrome protein (WASP) gene which encod

202 Wiskott-Aldrich syndrome protein (WASP) has emerged as a

203 No defects related to deficiency of the Wiskott-Aldrich Syndrome protein (WASp) have been descri

204 Mutations in the Wiskott-Aldrich syndrome protein (WASP) have been hypoth

205 f formins, known filament nucleators use the Wiskott-Aldrich syndrome protein (WASP) homology 2 (WH2

206 A role for Wiskott-Aldrich syndrome protein (WASP) in chemotaxis to

207 The role of the Wiskott-Aldrich syndrome protein (WASp) in platelet func

208 Wiskott-Aldrich Syndrome protein (WASp) is a hematopoiet

209 The Wiskott-Aldrich syndrome protein (WASP) is a key cytoske

210 The Wiskott-Aldrich syndrome protein (WASp) is a key regulat

211 The Wiskott-Aldrich syndrome protein (WASP) is a multi-domai

212 The Wiskott-Aldrich syndrome protein (WASP) is a product of

213 The Wiskott-Aldrich syndrome protein (WASP) is an effector o

214 In this study, we demonstrate that the Wiskott-Aldrich syndrome protein (WASp) is an essential

215 We demonstrate that the Wiskott-Aldrich syndrome protein (WASp) is an important

216 Wiskott-Aldrich syndrome protein (WASp) is essential for

217 The Wiskott-Aldrich syndrome protein (WASp) is important for

218 previously that tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) is important for

219 Wiskott-Aldrich syndrome protein (WASP) is in a complex

220 Here, we report that the Wiskott-Aldrich syndrome protein (WASp) is necessary for

221 ucleation by Arp2/3 complex activated by the Wiskott-Aldrich syndrome protein (WASP) or Scar protein;

222 Wiskott-Aldrich syndrome protein (WASP) plays a key role

223 The Wiskott-Aldrich syndrome protein (WASp) regulates actin

224 ed individuals reveals that mutations in the Wiskott-Aldrich syndrome protein (WASP) result in struct

225 utation (Leu270Pro) in the gene encoding the Wiskott-Aldrich syndrome protein (WASp) resulting in an

226 The Wiskott-Aldrich Syndrome protein (WASp) serves as a cruc

227 fic mutations in the human gene encoding the Wiskott-Aldrich syndrome protein (WASp) that compromise

228 LN) is caused by activating mutations in the Wiskott-Aldrich syndrome protein (WASP) that result in a

229 Here we have used cells deficient in the Wiskott-Aldrich syndrome protein (WASp) to demonstrate t

230 etal dysfunction caused by deficiency of the Wiskott-Aldrich syndrome protein (WASp) to explore the c

231 r receptor-bound protein 2 (Grb2) and to the Wiskott-Aldrich syndrome protein (WASp) to form a hetero

232 Whereas Cdc42 must activate Wiskott-Aldrich Syndrome protein (WASP) to stimulate nuc

233 Defects in Wiskott-Aldrich Syndrome protein (WASp) underlie develop

234 Mutations of Wiskott-Aldrich syndrome protein (WASP) underlie the sev

235 ds through its BAR domain and interacts with Wiskott-Aldrich Syndrome Protein (WASP) via its SRC homo

236 roteins involved in actin dynamics including Wiskott-Aldrich syndrome protein (WASp) were regulated b

237 ed via the phagocyte-specific kinase Hck and Wiskott-Aldrich syndrome protein (WASP), 2 major regulat

238 we demonstrated that ACK1 phosphorylates the Wiskott-Aldrich syndrome protein (WASP), a Cdc42 effecto

239 hat the PSTPIP SH3 domain interacts with the Wiskott-Aldrich syndrome protein (WASP), a cytoskeletal

240 s, develop in patients and mice deficient in Wiskott-Aldrich syndrome protein (WASP), a hematopoietic

241 protein, Bee1, exhibits sequence homology to Wiskott-Aldrich syndrome protein (WASP), a human protein

242 tients bearing inactivating mutations in the Wiskott-Aldrich syndrome protein (WASP), a key regulator

243 onsisting of WASp-interacting protein (WIP), Wiskott-Aldrich syndrome protein (WASp), actin, and myos

244 o the cytoskeleton through its effector, the Wiskott-Aldrich syndrome protein (WASP), activation of w

245 ynapse through focal nucleation of actin via Wiskott-Aldrich syndrome protein (WASP), and contraction

246 f, required an activating factor such as the Wiskott-Aldrich syndrome protein (WASP), and might exhib

247 rcent of natural killer (NK) cells expressed Wiskott-Aldrich syndrome protein (WASP), and NK cells co

248 HS1 interacts with Wiskott-Aldrich syndrome protein (WASp), another key act

249 The Wiskott-Aldrich syndrome protein (WASP), encoded by the

250 proline-rich protein that interacts with the Wiskott-Aldrich syndrome protein (WASP), from BJAB cell

251 teractions with a wide network of molecules: Wiskott-Aldrich syndrome protein (WASp), Grb2, ribosomal

252 One such effector, the Wiskott-Aldrich syndrome protein (WASP), is postulated t

253 se pulldown analyses show Robo4 binding to a Wiskott-Aldrich syndrome protein (WASP), neural Wiskott-

254 When activated by Wiskott-Aldrich Syndrome protein (WASp), the Arp2/3 comp

255 we provide evidence that Kit signals through Wiskott-Aldrich syndrome protein (WASP), the central hem

256 e B (PhyB) and fused the Cdc42 effector, the Wiskott-Aldrich Syndrome Protein (WASP), to the light-de

257 Two such adaptor proteins, Nck and the Wiskott-Aldrich syndrome protein (WASp), were recruited

258 Podosome formation requires the Wiskott-Aldrich syndrome protein (WASP), which is a prod

259 hat branching occurs when Arp2/3 is bound to Wiskott-Aldrich syndrome protein (WASP), which is in tur

260 racts through its SH3 domains with the human Wiskott-Aldrich syndrome protein (WASp), which plays a r

261 Here we show that deficiency of Wiskott-Aldrich syndrome protein (WASp), which signals t

262 edly reduced in macrophages deficient in the Wiskott-Aldrich syndrome protein (WASP), which still con

263 WAVE1--the Wiskott-Aldrich syndrome protein (WASP)--family verproli

264 for the assembly of filopodia-like bundles: Wiskott-Aldrich syndrome protein (WASP)-coated beads, ac

265 tients with the Wiskott-Aldrich syndrome and Wiskott-Aldrich syndrome protein (WASP)-deficient mice,

266 Wiskott-Aldrich syndrome protein (WASP)-deficient T cell

267 Here, we show that Wiskott-Aldrich syndrome protein (WASP)-family verprolin

268 P) intracellular domain (AICD) downregulates Wiskott-Aldrich syndrome protein (WASP)-family verprolin

269 Wiskott-Aldrich syndrome protein (WASP)-homology domain

270 Here, we demonstrate that Wiskott-Aldrich syndrome protein (WASp)-interacting prot

271 Wiskott-Aldrich syndrome protein (WASP)-interacting prot

272 s, where it was activated by p78/83, a viral Wiskott-Aldrich syndrome protein (WASP)-like protein.

273 e, Sos-activated Ras signaling and the human Wiskott-Aldrich Syndrome protein (WASp)-mediated actin c

274 recognize other motility proteins, like the Wiskott-Aldrich syndrome protein (WASP).

275 r of the actin cytoskeleton and activator of Wiskott-Aldrich syndrome protein (WASP).

276 The gene defective in WAS encodes Wiskott-Aldrich syndrome protein (WASP).

277 ematopoietic-specific cytoskeletal regulator Wiskott-Aldrich syndrome protein (WASP).

278 lex by the actin nucleation-promoting factor Wiskott-Aldrich Syndrome protein (WASp).

279 olled by signaling pathways that include the Wiskott-Aldrich syndrome protein (WASP).

280 ional change in its downstream effector, the Wiskott-Aldrich syndrome protein (WASP).

281 inase (ACK), p21-activated kinase (PAK), and Wiskott-Aldrich syndrome protein (WASP).

282 A related switch has been seen in the Wiskott-Aldrich syndrome protein (WASP).

283 m using a peptide substrate derived from the Wiskott-Aldrich Syndrome Protein (WASP).

284 inhibit the ability of Nwk-SH3a to activate Wiskott-Aldrich syndrome protein (WASp)/actin related pr

285 mparable to podosomes in the localization of Wiskott-Aldrich syndrome protein (WASP)/matrix metallopr

286 Nucleation-promoting factors (NPFs) of the Wiskott-Aldrich syndrome protein (WASP)/Scar family are

287 In animal cells and yeasts, Wiskott-Aldrich Syndrome protein (WASP)/suppressor of cA

288 The protein N-WASP [a homolog to the Wiskott-Aldrich syndrome protein (WASP)] regulates actin

289 lex must bind ATP, protein activators [e.g., Wiskott-Aldrich syndrome protein (WASp)], and the side o

290 Two molecules were isolated, the Wiskott-Aldrich syndrome protein (WASP, a putative CDC42

291 Wiskott-Aldrich syndrome proteins (WASP) are a family of

292 ycolactone-mediated activation of neural (N) Wiskott-Aldrich syndrome proteins (WASP) induces defects

293 /3 complex activation domain (WCA) of Las17 (Wiskott-Aldrich syndrome protein [WASp] homologue) fused

294 complex and in Bee1p/Las17p, a member of the Wiskott-Aldrich syndrome protein(WASP) family, lead to a

295 The Wiskott-Aldrich syndrome protein, WASP, is an adaptor pr

296 Wiskott-Aldrich syndrome protein (WASPs) control actin d

297 Wiskott-Aldrich syndrome proteins (WASPs), the prototypi

298 the DSH3PX1 SH3 domain interaction with the Wiskott-Aldrich Syndrome protein while enabling DSH3PX1

299 This includes Wiskott-Aldrich syndrome protein, Wiskott-Aldrich syndro

300 lation increased the association of neuronal Wiskott-Aldrich syndrome protein with Cdc42 and the Arp2