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1 Y chromosomes are typically viewed as genetic wastelands
2 Y-STR data were used to test different out-of-Africa mig
3 Y-STRs have emerged as important forensic and population
4 Y. pestis-infected Mefv(M680I/M680I) FMF knock-in mice e
5 m in spark plasma sintered Fe(48)Cr(15)Mo(14)Y(2)C(15)B(6) metallic glass is established by analyzing
6 eukaryotic translation initiation factor 1A Y-linked, together with its X-linked homolog EIF1AX Evol
7 can enter the hydrophobic cavity of alpha(3)Y and hydrogen bond to Y(32), as well as the possibility
8 g one pH- and redox-active tyrosine (alpha(3)Y and peptide A), and two proteins that contain multiple
10 A clinical cohort study (N = 70) showed 40% Y-BOCS score improvement during DBS, and a prospective i
14 )Y complexes as radiopharmaceuticals and (86)Y tracers for positron emission tomography (PET) imaging
15 ing and rapid normal-tissue clearance of (86)Y-NM600 were noted in both 4T07 and 4T1 murine models.
20 T) achieved before and after Yttrium-90 ((90)Y) administration and to evaluate additional benefits du
21 ble yttrium isotopes to enable roles for (90)Y complexes as radiopharmaceuticals and (86)Y tracers fo
22 tered activity for a therapy infusion of (90)Y-DOTA-BC8 were 0.35 +/- 0.20 cGy/MBq for red marrow, 0.
23 NET patients received up to 4 cycles of (90)Y-DOTATOC at 1.85 GBq/m(2)/cycle with a maximal kidney b
25 with glass microspheres were imaged with (90)Y PET/CT for voxel-level dosimetry to determine lesion a
27 ocrine tumor (NET) patients treated with (90)Y-DOTATOC in the setting of a prospective phase II trial
30 -Arg-Leu-Arg-Tyr-NH(2) (1), reported to be a Y(4)R partial agonist with high affinity (pK(i) Y(4)R: 8
31 etrapeptide (Arg-Leu-Arg-Tyr-NH(2)), being a Y(4)R partial agonist with unchanged Y(4)R affinity (pK(
32 olleagues report a micropeptide encoded by a Y chromosome-linked lncRNA that may explain the higher i
33 gulation of male sexual differentiation by a Y chromosome-linked male determining factor (M-factor) i
34 male sterility, while the upregulation of a Y allele of a cytokinin regulator (APRT3) may cause fema
35 linked homolog EIF1AX Evolutionary loss of a Y-linked microRNA target site enabled up-regulation of E
38 r findings demonstrate that self-adjuvanting Y. pestis OMVs provide a novel plague vaccine candidate
44 cell-cycle-related cyclins A, B, D, G/I and Y, and transcriptional cyclin L, were identified in the
45 acteristic in-plane chemical order of Mo and Y/Sc and Kagome ordering of the Al atoms, as evident fro
46 othesis was that PS-induced changes in Q and Y would improve central and local mechanisms of Q contro
48 to investigate this hypothesis, as the X and Y chromosomes are cytologically homomorphic and evolved
52 stically cue retrieval of task demands X and Y, respectively), and the role of the hippocampus and do
55 ng genomic and historical data, we assembled Y. pestis genomes from nine individuals covering four Eu
56 with IMD caused by meningococci serogroup B, Y, or C, adjusting for age, gender, and comorbidities.
60 us-type Y chromosome (Y (POS) ), known as B6.Y (POS) mice, commonly undergo gonadal sex reversal and
61 ity of hydrogen-bonding interactions between Y(32) and E(13), through structural fluctuations that re
64 eads that are properly aligned to the bovine Y sequence assembly accounted for 46.49%, indicating the
65 As in mice, an X-linked homolog of a bull Y-amplified gene has become testis-specific and amplifie
66 PA, the Ni bimetallic complexes supported by Y, Lu, and La form the Ni(eta(2)-alkyne) intermediate, (
67 (0.75> x <0.90) consistency, except for M1-C Y (0.73; examiner 1 to 2) and M1-M X (0.69; examiners 1
68 the inverse autotransporters (IATs), called Y. ruckeri invasin (YrInv) and Y. ruckeri invasin-like m
69 spheric retina, topological defects, called "Y-Junctions", form to maintain approximately constant ce
73 a Mus musculus domesticus-type Y chromosome (Y (POS) ), known as B6.Y (POS) mice, commonly undergo go
75 ditional functions, since the most conserved Y RNA contains a domain that is a close tRNA mimic and R
78 t years showed that tRNA halves and distinct Y RNA fragments are abundant in the extracellular space,
79 cate that GCP4, GCP5, and GCP6 form distinct Y-shaped assemblies that structurally mimic GCP2/GCP3 su
80 ys, K) and 3,4-Dihydroxyphenylalanine (DOPA, Y) residues in the mussel foot proteins (Mfps) has been
82 testis, we report many instances of elevated Y-Chromosome gene expression in a nonreproductive tissue
85 the beneficial effect of bariatric (Roux-en-Y gastric bypass [RYGB]) surgery on insulin resistance.
86 sity Surgery Registry, 509 patients (Roux-en-Y gastric bypass n=465; sleeve gastrectomy n=44) could b
87 patients who underwent laparoscopic Roux-en-Y gastric bypass procedure, in which comprehensive video
89 n morbidly obese subjects undergoing Roux-en-Y gastric bypass surgery compared to lean controls under
90 cancer and partial gastrectomy with Roux-en-Y reconstruction for nonhealing peptic ulcer presented t
92 the self-diffusion of a dye molecule (Eosin Y) in a series of polyacrylate networks with differing H
93 zing the visible-light absorptivity of Eosin Y for a reductive generation of alkyl radicals from N-(a
94 en; it was found that the diffusion of Eosin Y is significantly reduced in networks with H-bonding.
97 nappreciated epigenetic conflict on evolving Y chromosomes between transcription of essential genes a
100 am dependent on nuclear transcription factor Y subunit alpha (NFYa) and nuclear factor erythroid 2-li
101 8)M(0.2)Ru(2)O(7-delta) (M = Cu, Co, Ni, Fe, Y) controls the concentration of surface oxygen vacancie
102 dy is considered to be a putative marker for Y cells forming a motion processing stream, we suggest t
105 (coded by GCX), aspartic acid (coded by GAY [Y = U or C]), glutamic acid (coded by GAZ [Z = A or G]),
106 mprising the complete mitochondrial genomes, Y-chromosome markers, and genotypes of a number of nucle
109 omplete sequence assemblies of heteromorphic Y chromosomes have only been generated across a handful
112 G-protein-coupled receptors like the human Y(1) receptor (hY(1)R) are promising targets in cancer t
113 olds of the cholinesterase inhibitor huprine Y and the antioxidant capsaicin results in compounds wit
115 nce in situ hybridization directly implicate Y-specific genes that respectively suppress female (pist
122 , for which the Y site is similar to that in Y-SiO(2) but which lacks adjacent hydroxyl groups, and a
123 In the experiment, plants were trained in Y-shaped mazes for 3 days with fans and lights attached
125 f bacteria in the footpad revealed increased Y. pestis-neutrophil interactions and increased neutroph
126 erize the arrangement of cones in individual Y-Junction cores as well as the spatial distribution of
127 Chronic treatment with Rho-kinase inhibitor Y-27632 after chronic social defeat stress reverses depr
129 on of CCD from one item (X) to another item (Y) was predicted by a decrease in alpha power following
130 ))(3) afforded the heteroleptic complex, [{L}Y(N(SiMe(3))(2))(2)] (1), by elimination of HN(SiMe(3))(
131 Twelve months of DBS resulted in a mean Y-BOCS score decrease of 13.5 points (SD=9.4) (40% reduc
133 mutations that improved phenotypes in Mecp2/Y mice after mutagenesis with N-ethyl-N-nitrosourea (ENU
136 has an XY system and V. vinifera a modified Y haplotype (Yh) and that the sex locus is small, but it
140 with several distinct cases of neo-X and neo-Y formation, X-added regions, and conversion of autosome
142 parvalbumin, somatostatin, and neuropeptide Y also show unique topographical distributions, suggesti
143 the basolateral amygdala (BLA), neuropeptide Y (NPY) is associated with buffering the neural stress r
144 ction of Caenorhabditis elegans neuropeptide Y/neuropeptide F and serotonin that could aid in our und
146 uences IGL neurons that express neuropeptide Y (NPY) (hereafter, IGL(NPY) neurons), guiding the assem
147 er-modified microelectrodes for Neuropeptide Y measurement by electrochemical impedance spectroscopy
148 uropeptide receptors, including neuropeptide Y, gonadotropin inhibitory hormone (GnIH), pyroglutamyla
149 entral alpha-klotho to modulate neuropeptide Y/agouti-related peptide (NPY/AgRP)-expressing neurons,
152 ed the evolutionary ortholog of neuropeptide Y/neuropeptide F in the nematode Caenorhabditis elegans,
154 ce of both sexes, we found that neuropeptide Y (NPY) expression identifies a major class of inhibitor
155 inding motifs of members of the neuropeptide Y and glucagon families modulate receptor activation pro
156 conformational dynamics of the neuropeptide Y receptor type 2 (Y2R) during activation was investigat
157 -regulated genes preferentially contained NF-Y-binding motifs in their proximal promoters, and notabl
159 A heterotrimeric transcription factor NF-Y is crucial for cell-cycle progression in various types
162 Here, a root-specific nuclear factor Y (NF-Y) transcription factor PdNF-YB21 was isolated from Popu
164 (M = Si, Ge, Sn, Pb, Ti, Al, Cr, Fe, Ni...; Y = O, NR, CH(2), S), i.e., substituted 5-azabicyclo[3.3
166 We synthesized a series of peptidic NPY Y(4)R ligands, derived from the hexapeptide acetyl-Arg-T
167 nd Ai14 Cre-reporter mice, we found that NPY Y(1) receptor (Y(1)R)-expressing neurons are glutamaterg
168 he active centers for this process are =Si-O-Y(OH)-O-Si= or =Si-O-Zn-O-Si-O= groups closely associate
169 tem that oversynthesized the LcrV antigen of Y. pestis, raised the amounts of LcrV enclosed in OMVs b
177 (AGMs) after challenge with a lethal dose of Y. pestis delivered as an aerosol, in 4 independent stud
178 istribution and local bonding environment of Y and Nd, as proxies for heavy and light REE, in the dep
181 ate level could reflect the heterogeneity of Y cell subpopulations and the heterochrony of their post
182 ranscriptome analysis found that a number of Y chromosomal genes had altered expression patterns in t
183 gocytes in vitro and in vivo Opsonization of Y. pestis with polyclonal antiserum modestly increased p
188 ther, our data demonstrate that the roles of Y RNAs are intimately connected to that of their Ro60 pa
190 vitro FTY720 treatment downregulated CCR7 on Y. enterocolitica-infected bone marrow-derived DCs and p
191 we examine the effects of Ab opsonization on Y. pestis interactions with phagocytes in vitro and in v
192 sonizing Ab had a dramatic effect in vivo on Y. pestis-neutrophil interactions in the dermis and dLN
193 showed increased association of Ab-opsonized Y. pestis with neutrophils in the dermis in a mouse mode
195 to exons 2 and 3 of POLG but also affect ORF-Y provides potential clinical significance to this findi
200 Ribosome profiling data revealed that ORF-Y is translated and that initiation likely occurs at a C
201 nt of DNA polymerase eta (Pol eta) and other Y-family TLS polymerases to damaged DNA relies on prolif
203 46.49%, indicating the success in the ovine Y chromosome isolation and the high quality of the Y chr
204 encing, assembly and annotation of the ovine Y chromosome, but also provide a validated approach to o
206 ovel catalyst with improved OER performance, Y(1.8)Cu(0.2)Ru(2)O(7-delta), and provides general guide
211 substituent in yttrium ruthenium pyrochlores Y(1.8)M(0.2)Ru(2)O(7-delta) (M = Cu, Co, Ni, Fe, Y) cont
212 tyrosine produces a neutral tyrosyl radical (Y(*)) that is vital to many catalytic redox reactions.
214 S) effects on blood flow ( Q ), shear rate ( Y ), and vascular function in the feeding arteries of th
215 formation of new RE-MOFs, RE-ken-MOF-1 (RE: Y(3+), Ho(3+), Er(3+), Yb(3+)), that display an unpreced
216 orter mice, we found that NPY Y(1) receptor (Y(1)R)-expressing neurons are glutamatergic and were bro
217 eptide Y (NPY) receptors, the Y(4) receptor (Y(4)R) is unique as it prefers pancreatic polypeptide ov
218 genesis by increasing sex-determining region Y-box 2, nestin, and also enhances synaptic function thr
223 lemental space of these borides with M = Sc, Y, Zr, Hf, and Nb, realizing an increased property tunin
224 ence (Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score improved 37% during stimulation on), the o
228 hese isolates was similar to other serogroup Y isolates internationally, a distinct strain (YI) and m
230 Extensive comparisons between the serogroup Y sublineages of all coding sequences, complex genomic r
232 quence can therefore lead to tissue-specific Y-Chromosome-driven sex biases in expression of critical
233 and the disappearance of the trans-splicing Y structure intermediate, CRK9 is essential for the firs
234 to C1q and blocks its activity, and SRPX2(-/Y) mice show increased C3 deposition and microglial syna
237 ciated with C3(-/-) mice rather than SRPX2(-/Y) mice, which indicates that C3 is necessary for the ef
239 n identified an effector, with an N terminal Y/FxC motif, that induced a strong hypersensitive respon
249 super-resolution sequencing, we explore the Y Chromosome of Bos taurus (bull) and find it to be domi
251 negative correlation between the loss of the Y chromosome or linc-SPRY3-2/3/4 and overall survival.
254 owever, we lack comprehensive studies of the Y chromosomes of Denisovans and Neanderthals because the
256 important details about the function of the Y complex that affect our understanding of NPC structure
258 lies relative to females, and repeats on the Y chromosome are disproportionally mis-expressed during
259 amily of neuropeptide Y (NPY) receptors, the Y(4) receptor (Y(4)R) is unique as it prefers pancreatic
260 Y-DeAlBEA are 70 times more active than the Y sites supported on silica, for which the Y site is sim
261 uggest these forces are not exclusive to the Y chromosome, and chromosomal degeneration may have occu
262 e Y sites supported on silica, for which the Y site is similar to that in Y-SiO(2) but which lacks ad
263 mer can bind the HIV gp41 epitope, while the Y(cis)P is not binding competent and shows a higher aggr
264 t on the importance of neutrophils in AMI to Y. pestis and may provide a new correlate of protection
266 bic cavity of alpha(3)Y and hydrogen bond to Y(32), as well as the possibility of hydrogen-bonding in
269 s lends support to the idea that the 'toxic' Y chromosome can create a mutational burden in males whe
270 u in 1 and in derivatives of 1 by Trp turned Y(4)R agonism to antagonism, giving Y(4)R antagonists wi
271 ice harboring a Mus musculus domesticus-type Y chromosome (Y (POS) ), known as B6.Y (POS) mice, commo
276 This study describes previously unknown Y chromosome-expressed lncRNA regulators of radiation re
278 K, Mn, Mo, Na, Ni, P, Pb, Th, Tl, Sb, U, V, Y and Zn) in 73 commercial products marketed in Spain.
280 y input and induced dendritic hypotrophy via Y(5) receptor activation; conversely, CRF increased exci
281 ge and SBA concentration (X) are related via Y = -0.034 X +737.40, with a determination coefficient o
283 We constructed six Env375 variants (M, H, W, Y, F, and S) for each SHIV, and we performed a pool comp
284 ere phenotypically female; however, 58% were Y chromosome-positive, resembling the phenotype of human
285 results indicated that 68.90% of reads were Y chromosome-related sequences as they are homologous to
287 s a graded rather than a binary switch, with Y- or W106 side-chain burial correlated with increased F
289 e, we provide evidence that suppression of X-Y crossing-over unleashed a second dynamic: selfish X-Y
290 g-over unleashed a second dynamic: selfish X-Y arms races that reshaped the sex chromosomes in mammal
291 convergence implies that lineage-specific X-Y coevolution through gene amplification, and the selfis
294 understanding of how flies with a typical X/Y heterogametic amphogeny (male and female offspring in
295 of E-selectin and ICAM-1, obtained at year (Y) 7 (Y7) and Y15 examinations, with cardiac function as