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1 formational stability of the chaperone LcrH (Yersinia pestis).
2 trophic European Black Death/bubonic plague (Yersinia pestis).
3 major surface protein of the deadly pathogen Yersinia pestis.
4 om the genome of the closely related species Yersinia pestis.
5 oding putative c-di-GMP metabolic enzymes in Yersinia pestis.
6 -encoded type III secretion system (T3SS) of Yersinia pestis.
7 tes, obesity, and infection by the bacterium Yersinia pestis.
8 rulence protein YopM of the plague bacterium Yersinia pestis.
9 were challenged with inhaled lethal doses of Yersinia pestis.
10 in human history, is caused by the bacterium Yersinia pestis.
11 ics against the potential bioterrorism agent Yersinia pestis.
12 including CDC category A/B pathogens such as Yersinia pestis.
13 nto eukaryotic cells by the plague bacterium Yersinia pestis.
14 tions, is transmitted by fleas infected with Yersinia pestis.
15 re resistant to several pathogens, including Yersinia pestis.
16 nctioning in Yersinia pseudotuberculosis and Yersinia pestis.
17 hilum, and five (2.7%) were seropositive for Yersinia pestis.
18 the phosphatase YopH, a bacterial toxin from Yersinia pestis.
19 cterial pathogens Listeria monocytogenes and Yersinia pestis.
20 ncient plague strains are basal to all known Yersinia pestis.
21 genome sequences, of which the majority are Yersinia pestis.
22 ue is a deadly respiratory disease caused by Yersinia pestis.
23 ement for Hfq in the closely related species Yersinia pestis.
26 Here we studied the interaction between the Yersinia pestis ABC heme importer (HmuUV) and its partne
29 he consequence of a singular introduction of Yersinia pestis, after which the disease established its
30 specially potential bioterrorism agents like Yersinia pestis and Bacillus anthracis which feature on
31 -resistant Staphylococcus aureus, as well as Yersinia pestis and Bacillus anthracis, organisms of bio
33 the strictly conserved glycine to serine in Yersinia pestis and Escherichia coli topoisomerase I res
35 ly or intratracheally with the F1 antigen of Yersinia pestis and flagellin exhibited dramatic increas
36 tant of 20 nM between EGFP-labeled LcrV from Yersinia pestis and its cognate membrane-bound protein Y
38 he cell surface of both Escherichia coli and Yersinia pestis and show that a subset of these proteins
39 o systemic infection with the KIM5 strain of Yersinia pestis and that B10.T(6R) mice become susceptib
40 tant to pigmentation locus-negative (pgm(-)) Yersinia pestis and that this phenotype maps to a 30-cen
41 s both the protective F1 capsular antigen of Yersinia pestis and the LcrV protein required for secret
42 e identification of new virulence factors in Yersinia pestis and understanding their molecular mechan
44 owed differences in virulence genes found in Yersinia pestis and Yersinia pseudotuberculosis compared
45 nt of YopJ-dependent cytotoxicity induced by Yersinia pestis and Yersinia pseudotuberculosis paradoxi
46 ages were infected with a panel of different Yersinia pestis and Yersinia pseudotuberculosis strains
49 flammatory response induced by other lethal (Yersinia pestis) and non-lethal (Legionella pneumophila,
50 a and Salmonella enterica serovar Typhi, and Yersinia pestis), and 3 protozoa (Leishmania spp., Plasm
51 athogenicity island, originally described in Yersinia pestis, and encodes proteins with apparent homo
54 des genes from pathogens such as Salmonella, Yersinia pestis, and the virulent Francisella tularensis
55 ncisella tularensis, Bacillus anthracis, and Yersinia pestis are tier 1 select agents with the potent
56 plague, the most severe form of infection by Yersinia pestis, are needed, as past US Food and Drug Ad
58 ut a potential use of the causative bacteria Yersinia pestis as an agent of biological warfare have h
59 gens, including the plague causing bacterium Yersinia pestis, avoid activating this pathway to enhanc
60 ion of either Yersinia pseudotuberculosis or Yersinia pestis bacteria express the small RNAs YSR35 or
61 t historically documented pandemic caused by Yersinia pestis began as the Justinianic Plague in 541 w
62 molecule cyclic diguanylate is essential for Yersinia pestis biofilm formation that is important for
64 and type of medium peptides associated with Yersinia pestis biomass and improve the quality of prote
65 a) in a 19th century intestinal specimen and Yersinia pestis ("Black Death" plague) in a medieval too
66 Several gram-negative pathogens, including Yersinia pestis, Burkholderia cepacia, and Acinetobacter
67 include the bacteria Francisella tularensis, Yersinia pestis, Burkholderia mallei, and Brucella speci
68 ity pathogens, including Bacillus anthracis, Yersinia pestis, Burkholderia mallei, Francisella tulare
70 for the type III secretion system (T3SS) in Yersinia pestis by interaction with the negative regulat
71 nto a constitutively active IpaH enzyme from Yersinia pestis by introduction of single site substitut
72 trument's response to Bacillus anthracis and Yersinia pestis by spiking the liquid sample stream with
73 es the invasiveness of the plague bacterium, Yersinia pestis, by activating plasminogen to plasmin to
76 ine against plague currently consists of the Yersinia pestis capsular antigen F1 and the type 3 secre
89 tructures of three active-site complexes for Yersinia pestis class IV AC (AC-IV)-two with substrate a
90 aled dose of 1.02 x 10(6) CFU of aerosolized Yersinia pestis CO92 (50% lethal dose, 6.8 x 10(4) CFU).
92 Braun lipoprotein (Lpp) and MsbB attenuated Yersinia pestis CO92 in mouse and rat models of bubonic
93 sal instillation of a fully virulent strain, Yersinia pestis CO92, guinea pigs developed lethal lung
96 a multifunctional outer membrane protein of Yersinia pestis, confers cell binding, Yop delivery and
102 l infection of BALB/c mice with nonpigmented Yersinia pestis does not result in pneumonic plague.
103 ts the most severe form of disease caused by Yersinia pestis due to its ease of transmission, rapid p
104 ylase (KdoO) from Burkholderia ambifaria and Yersinia pestis, encoded by the bamb_0774 (BakdoO) and t
105 iosynthesis from Mycobacterium tuberculosis, Yersinia pestis, Escherichia coli, Vibrio cholerae, Baci
107 In American grasslands, plague, caused by Yersinia pestis, exemplifies this quiescent-outbreak pat
108 0 degrees C), the causative agent of plague, Yersinia pestis, expresses a profile of genes distinct f
109 of mice with a recombinant fusion protein of Yersinia pestis F1 and LcrV Ags (F1-V) together with EdT
110 plant-made plague vaccine, we expressed the Yersinia pestis F1-V antigen fusion protein in tomato.
111 vaccine, we expressed our model antigen, the Yersinia pestis F1-V antigen fusion protein, with and wi
112 pture-based immunochromatographic dipsticks, Yersinia Pestis (F1) Smart II and Plague BioThreat Alert
113 ewanella oneidensis, Salmonella typhimurium, Yersinia pestis) for training and validation within and
114 s, Bacteroides fragilis, Bacillus anthracis, Yersinia pestis, Francisella tularensis, and Brucella ab
115 aromyces cerevisiae, Pseudomonas aeruginosa, Yersinia pestis, Francisella tularensis, Bacillus anthra
116 uences were designed for Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella melite
117 acids from BT organisms (Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella spp.,
118 -six distinct strains of Bacillus anthracis, Yersinia pestis, Francisella tularensis, Burkholderia ma
119 lytic domains from four pathogenic bacteria: Yersinia pestis, Francisella tularensis, Burkholderia ps
121 entional autotransporters are present in the Yersinia pestis genome, but only one, YapE, is conserved
124 ated human pathogens Salmonella enterica and Yersinia pestis has entailed functional changes in the P
129 utic strategies that prevent infections with Yersinia pestis have been sought for over a century.
130 ere, we report the oldest direct evidence of Yersinia pestis identified by ancient DNA in human teeth
131 tudies (influenza A in lesser snow geese and Yersinia pestis in coyotes), we argue that with careful
132 ery that regulates the entry and survival of Yersinia pestis in host macrophages is poorly understood
135 ated with iron(III)-yersiniabactin import in Yersinia pestis In this study, we compared the impact of
138 ns cause host cell death upon infection, and Yersinia pestis, infamous for its role in large pandemic
139 HMBPP/IL-2 administration after inhalational Yersinia pestis infection induced marked expansion of Vg
142 n lymph nodes (LNs), or buboes, characterize Yersinia pestis infection, yet how they form and functio
167 ds that the causative agent of this disease, Yersinia pestis, is able to survive and multiply in both
168 lague, caused by the Gram-negative bacterium Yersinia pestis, is favored by a robust early innate imm
171 e is the deadliest form of disease caused by Yersinia pestis Key to the progression of infection is t
173 s from cultures of two attenuated strains of Yersinia pestis [KIM D27 (pgm-) and KIM D1 (lcr-)] grown
174 genomic DNA near IL-10 confers resistance to Yersinia pestis KIM5 and contributes to the observed res
176 ive TnphoA mutant library was constructed in Yersinia pestis KIM6 to identify surface proteins involv
177 ing the human pathogens Burkholderia mallei, Yersinia pestis, Klebsiella pneumoniae, Legionella longb
178 Since possible exposure to plague is via Yersinia pestis-laden aerosols that results in pneumonic
180 d monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a
185 cessfully produce disease, the causal agent (Yersinia pestis) must rapidly sense and respond to rapid
186 onment where the agent of flea-borne plague, Yersinia pestis, must replicate to produce a transmissib
188 ng disease throughout human history, such as Yersinia pestis, Mycobacterium tuberculosis, and Mycobac
189 biothreat agents such as Bacillus anthracis, Yersinia pestis, or Burkholderia pseudomallei Convention
192 high mortality, but the mechanisms by which Yersinia pestis overwhelms the lungs are largely unknown
198 d release of Bacillus anthracis (anthrax) or Yersinia pestis (plague) would prompt a public health em
199 lly attenuated, pigmentation (Pgm)-deficient Yersinia pestis primes T cells that protect mice against
200 rate chain to the 2' position of lipid A, in Yersinia pestis produced bisphosphoryl hexa-acylated lip
203 ymerization of a single protein, e.g., YscF (Yersinia pestis), PscF (Pseudomonas aeruginosa), PrgI (S
204 n model of pneumonic plague, it appears that Yersinia pestis quickly creates a localized, dominant an
207 Pneumonic plague, caused by inhalation of Yersinia pestis, represents a major bioterrorism threat
212 hat the base pairing function of E. coli and Yersinia pestis SgrS homologs is critical for rescue fro
215 orical interest - pre-modern bubonic plague (Yersinia pestis), smallpox (Variola virus) and cholera (
216 to approximately 100 50% effective doses of Yersinia pestis strain CO92 and necropsied at 24-h inter
218 lague, we have sequenced the genomes of four Yersinia pestis strains isolated from the zoonotic roden
220 malian body temperature, the plague bacillus Yersinia pestis synthesizes lipopolysaccharide (LPS)-lip
221 roinflammatory responses through TLRs by the Yersinia pestis T3S needle protein, YscF, the Salmonella
222 f the enzootic maintenance of the bacterium (Yersinia pestis) that causes plague and the sporadic epi
225 nse is a prominent feature of infection with Yersinia pestis, the agent of bubonic and pneumonic plag
227 r gene products are functional receptors for Yersinia pestis, the agent of plague, as shown by overex
231 The arthropod-borne transmission route of Yersinia pestis, the bacterial agent of plague, is a rec
234 ly, there is no FDA-approved vaccine against Yersinia pestis, the causative agent of bubonic and pneu
241 hat distinguish DNA amplicons generated from Yersinia pestis, the causative agent of plague, from the
264 t the discovery and genome reconstruction of Yersinia pestis, the etiological agent of plague, in Neo
266 in the delivery of cytotoxic Yop proteins by Yersinia pestis, the mechanism has not been defined.
268 lethal human disease caused by the bacterium Yersinia pestis This study demonstrated that the Y. pest
270 edium- to high-copy-number plasmid clones of Yersinia pestis topoisomerase I (YpTOP) with Asp-to-Asn
271 hionine residue with arginine in recombinant Yersinia pestis topoisomerase I (YTOP) was the only subs
273 mal system for interrogating such couplings: Yersinia pestis transmission exerts intense selective pr
276 n, the serine/threonine kinase YopO (YpkA in Yersinia pestis), uses monomeric actin as bait to recrui
278 ulation tests for Francisella tularensis and Yersinia pestis, using a well-established hybridization
280 the possible role of Na(+)/H(+) antiport in Yersinia pestis virulence and found that Y. pestis strai
281 To validate these vector attributes, the Yersinia pestis virulence antigen LcrV was used to devel
282 Mutant pyrin interacts less avidly with Yersinia pestis virulence factor YopM than with wild-typ
283 es that demonstrated a role played by Lpp in Yersinia pestis virulence in mouse models of bubonic and
284 ro, His-tagged recombinant LcrV (rLcrV) from Yersinia pestis was cloned and expressed in Escherichia
285 for antimicrobial susceptibility testing of Yersinia pestis was evaluated in comparison with broth m
286 tion of the highly virulent plague bacterium Yersinia pestis was the acquisition of plasmid pPCP1, wh
287 end, immunity to LcrV, a protective Ag from Yersinia pestis, was tested in young and old baboons.
288 and genome evolution of the plague bacterium Yersinia pestis, we have sequenced the deep-rooted strai
289 atory mice are usually highly susceptible to Yersinia pestis, we recently identified a mouse strain (
290 .3, raised to the LcrV virulence factor from Yersinia pestis were characterised for their Fab affinit
291 that includes serious pathogens such as the Yersinia pestis, which causes plague, Yersinia pseudotub
293 ent resistance) in the pathogenic Yersiniae (Yersinia pestis, Y. enterocolitica, and Y. pseudotubercu
295 of Vibrio cholerae vibriobactin and HMWP2 of Yersinia pestis yersiniabactin assembly lines were evolv
297 eins, the Shigella flexneri OspF protein and Yersinia pestis YopH protein, to rewire kinase-mediated
298 e of the class IV adenylyl cyclase (AC) from Yersinia pestis (Yp) is reported at 1.9 A resolution.