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1  a natural solution allowing the encoding of a desired 3D architecture into the chemical building blo
2 d layer-by-layer assembly of biomaterials in a desired 3D pattern.
3 tion, consistent with a strategy to maintain a desired accumulation of reward.
4        Designing the channel that results in a desired acoustic field, however, is a non-trivial task
5 of an intracellular selection process toward a desired activity; and (iii) the characterization of th
6 fting, that permits selective inheritance of a desired allele located in close proximity to the gRNA
7 ning of random peptides and RNA created with a desired amino acid and nucleotide composition, as well
8 ivity of conjugated polymer materials toward a desired analytical target would further benefit their
9                  Choosing the "best fit" for a desired application is critical.
10 lso play a large part in the suitability for a desired application.
11 mpare their self-produced speech signal with a desired auditory target and correct for errors.
12 nd then calculate the sample size to achieve a desired average power while controlling FDR.
13  nucleobase conformations of an RNA to match a desired backbone, analogous to fundamental tools that
14 binations of kinetic parameters that produce a desired behavior in a genetic network.
15 efficient of hygroscopic expansion to target a desired behavior such as multimodal locomotion.
16 nd construct biological systems that present a desired behavior.
17 sts to train an animal (or human) to produce a desired behavior.
18 o establish the neural patterns that produce a desired behavioral outcome.
19 namic model of a larger device that exhibits a desired behaviour.
20 arantee cell viability and eventually induce a desired behaviour.
21 nd by screening large chemical libraries for a desired biological effect and, conversely, ensuring bi
22 diction of compounds that are active against a desired biological target is a common step in drug dis
23 th a metric that may be monitored to enforce a desired bound on accuracy within a user-defined confid
24 distract themselves to cope with waiting for a desired but delayed reward.
25  activation energy and selectively producing a desired but kinetically unfavourable product for the i
26 his system to elucidate the connections onto a desired cell type in a high-throughput manner, limited
27 get lentivirus-mediated gene transduction to a desired cell type.
28 rated, systems-level approach for optimizing a desired cellular property or phenotype; and great stri
29                                              A desired characteristic of candidate antimalarials is r
30                       Long-term stability is a desired characteristic of vaccines, especially anthrax
31 for the introduction of de novo activity for a desired chemical reaction.
32 teins to allow chemical-induced proximity of a desired chromatin regulator.
33 ation scheme is a powerful method of finding a desired chromatographic separation based on a small nu
34 E, is a clean approach of gene delivery into a desired chromosomal location, as it is able to insert
35              Design automation software maps a desired circuit function to a DNA sequence, a process
36 raft an effective vaccine formulation toward a desired clinical benefit for a clinical vaccine to max
37 t and additives) of a successful reaction to a desired, closely related reaction using a new substrat
38 sonalized multi-pathway diagrams that depict a desired collection of interacting pathways that emphas
39                    The third group displayed a desired combination of diminished general toxicity and
40 st and then is isothermally transformed into a desired, complicated nanocage.
41 ity to prepare noble metal nanostructures of a desired composition, size, and shape enables their res
42 o further enhance heterologous production of a desired compound may be limited by the inherent capaci
43 olic flux, and thereby increase the yield of a desired compound.
44 urface is critical for exclusively accessing a desired configuration.
45 d high-performance liquid chromatography had a desired correlation (R(2)=0.9958).
46 stimating the sequencing depth necessary for a desired coverage of protein binding sites.
47 ast bound, the needed exposure time to reach a desired CPE without empirical model inputs.
48 nanocrystal concentration to be adjusted and a desired crystal size to be prepared at full conversion
49 mpossible to rationalize and control to give a desired crystal symmetry, lattice spacing and habit (c
50 listimethate that would be needed to achieve a desired Css,avg and creatinine clearance.
51 for determining the FeTot required to effect a desired %Cvn is presented.
52                            With this method, a desired cysteine can be reversibly protected by bindin
53  be difficult to obtain specific labeling of a desired cysteine in proteins with multiple cysteines,
54 e design of the multivalent probe, to target a desired density of binding sites.
55  controlled, three-dimensional structures in a desired direction, and expands the current tools avail
56 mine whether the packing can be steered into a desired direction, so to allow topochemical photopolym
57 ve the immune response and/or direct it into a desired direction.
58 ising metabolic cost per unit of distance in a desired direction.
59 erior colliculus (SC) is thought to generate a desired displacement command specifying the amplitude
60  microbubble was generated and positioned at a desired distance from the membrane of a Xenopus oocyte
61 served in a simulation, rather than assuming a desired distribution has been generated.
62  plant transformation method, plantlets with a desired DNA change were regenerated in <6 weeks.
63 eminivirus replicons to generate plants with a desired DNA sequence modification.
64 physician to titrate sedative medications to a desired effect and thereby reduce the risks associated
65 so penetrate the brain parenchyma to achieve a desired effect within the brain.
66 icts meta surface design parameters based on a desired electromagnetic field outcome.
67 talyst surface and the targeted synthesis of a desired enantiomer requires the implantation of chiral
68  investigate the potential for introgressing a desired engineered gene into a pest population by link
69 es to facilitate isolation of cells in which a desired engineering outcome has occurred.
70  that produces high affinity antibodies with a desired epitope coverage profile, resulting in the gen
71 Developing electromagnetic pulses to produce a desired evolution in the presence of such variation is
72 ntify interventions that force a cell toward a desired expression state.
73  free drug from the covalently bound form in a desired fashion.
74 ation of cross-links over peptide backbones, a desired feature for MS(n) analysis.
75             However, this combination is not a desired feature in other experimental and therapeutic
76 ic organ, cellular and sub-cellular level is a desired feature of a drug carrier system.
77 the platform to force yeast cells to express a desired fixed, or time-varying, amount of a reporter p
78 e data were then used for line selection for a desired flavor profile.
79 lem of designing a flow sculpting device for a desired fluid flow shape remains a challenge.
80 lii) either had to determine the location of a desired food item or a property of a non-food item (le
81 ivity of constituent cells to evolve towards a desired form and function.
82 p enhance the signal power at the output, in a desired frequency range.
83 n source to deflect electromagnetic waves at a desired frequency, ranging from millimeter-wave to far
84 n a synthetic device and can be tailored for a desired frequency.
85         When engineering biological systems, a desired function must be achieved in a context that is
86 with the host cell can cause deviations from a desired function, resulting in the need for time-consu
87 r development of beta-peptoid foldamers with a desired function, such as catalytic properties or as s
88 an fold into structures capable of eliciting a desired function.
89 evant assays to identify proteins possessing a desired function.
90 ral (AAV) libraries that can be selected for a desired function.
91 ll subpopulations work together to carry out a desired function.
92 neers are able to design proteins to perform a desired function.
93 rmation of a given fiber network to optimize a desired function.
94 s the efficient isolation of antibodies with a desired functional characteristic without prior knowle
95 gut microbiome can be modified directly with a desired genetic payload.
96  editing for selecting engineered cells with a desired genotype but the variety of markers is limited
97  is the drive system, which serves to spread a desired genotype into the targeted field population.
98 surface science are to induce fractures with a desired geometry and to adaptively control the interst
99 lls directed against a target autoantigen is a desired goal of experimental approaches for the treatm
100 Although the reduction of clinical stroke is a desired goal, the current research design of embolic p
101 to plan and enact a sequence of tasks toward a desired goal.
102 m for constructing a potential function with a desired ground state.
103 sophila, Cas9 expression could be limited to a desired group of cells, allowing tissue-specific mutag
104 his could lead to unexpected deviations from a desired growth pathway.
105 ive in vitro axonal extension over 5 mm with a desired growth rate of approximately 1 mm/day.
106 trol the arrangement and binding strength of a desired guest.
107 "center of mass" of large shapes: ants learn a desired heading toward a point on a distant shape as t
108  in predictions while keeping specificity in a desired high range.
109 s choice of a TE may allow the production of a desired hybrid metabolite.
110  with single-stranded probe DNAs, to capture a desired hybridization event.
111 as a tool to identify critical components of a desired immune response.
112 d to direct macrophage polarization to drive a desired immune response.
113 cific DNA sequences and subsequently trigger a desired intracellular response.
114 ontrolling the assembly of these chains with a desired length.
115  negative rate of the screening algorithm to a desired level (5% in this study) is achieved.
116 ower with false discovery rate controlled at a desired level and is robust to the unimodal distributi
117 imating the depth of sequencing required for a desired level of coverage and demonstrating that more
118 otein-binding sites, while still maintaining a desired level of false positive calls.
119 ht the key design criteria needed to achieve a desired level of public health benefit.
120  for the isolation of sequences that exhibit a desired level of stability.
121 ame RNA molecule to reduce the error rate to a desired level, and they also enable accurate quantific
122 ngineer any intron to increase expression to a desired level, and to explore the mechanism of IME by
123 f logarithms of likelihood ratios (logLR) to a desired level.
124 educe the uncertainty in period estimates to a desired level.
125 se discovery rate (FDR) can be controlled at a desired level.
126 hile controlling the false discovery rate at a desired level.
127 an be designed by precycling an electrode in a desired Li- or Na-based electrolyte, and that ionic tr
128 hanges in gene expression in the presence of a desired ligand.
129 hat the motor system computes and implements a desired limb trajectory, an intermediary control proce
130 -PAINT, and upon visualization of binding to a desired location, photo-crosslinks the DNA to affix th
131  only start working after they are placed in a desired location.
132  the control process of moving the carton to a desired location.
133 t possible to precisely position the line at a desired location.
134 identifying nodes to drive the system toward a desired long-term behavior, prioritizing combinations
135 MOF layer needed to attenuate shock waves to a desired lower energy.
136 indows (of 10 m/z) within the ion trap until a desired mass range has been covered.
137                                     Glass is a desired material for many microfluidics applications.
138 ycloserine has the therapeutic properties of a desired medication for ASDs; specifically, a medicatio
139 through space to direct an addressee towards a desired mental state.
140 ative strategy to increase the production of a desired metabolite.
141 lt casting is impossible or does not achieve a desired microstructure, and has long been pursued for
142  stratification of the final components with a desired microstructure.
143 trieving, transporting, and repositioning to a desired microwell on the array.
144 ate the expected number of new variants with a desired minimum frequency to be discovered in a new da
145 that is used to selectively transmit ions of a desired mobility.
146 fic epitopes on the target molecule to exert a desired modulation of biological function.
147 al validation on a cobalt-C3N4 catalyst with a desired molecular configuration, which possesses compa
148 e-tagged antibodies, each being specific for a desired molecular target, quantification of each molec
149 thermodynamics closely approximating that of a desired motif is numerically calculated from directly
150 eaction flux data onto the collage to obtain a desired multi-pathway diagram.
151 he need to screen a large random library for a desired mutant plant.
152 ters of the protein Hamiltonian to fold into a desired native structure.
153 ions to those correlated with recognition of a desired new base to create enzymes that recognize and
154 le means to provide sufficient quantities of a desired NP while using inexpensive renewable resources
155                                  However, if a desired nucleic acid sequence could be translated in v
156 s: feedback-controlled selective delivery of a desired number of biomolecules and integration of opti
157 rolyzed in a controlled fashion to introduce a desired number of carboxylic acid groups to the intern
158 ransferases to specifically methylate DNA at a desired number of sites that serve as probes of struct
159  of requesting or drawing their attention to a desired object or food.
160 species' metabolisms will integrate to reach a desired outcome is a difficult problem that has been s
161            These results show that achieving a desired outcome often necessitates roundabout steps.
162  a system works where allograft rejection is a desired outcome rather than an unforeseen consequence.
163 es knowing whether a past action resulted in a desired outcome.
164 tegy, even when it is beneficial, to achieve a desired outcome.
165 pically tuned manually to subjectively match a desired output.
166          Furthermore, the method selects for a desired particle size and produces a monodisperse agen
167  functionalities, to conjugate moieties into a desired pattern, enabling the creation of a wide varie
168 thesize an electromagnetic metamaterial with a desired permittivity, using as building blocks only tw
169 atalytic metallodrug are required to achieve a desired pharmacologic effect, and therefore, toxicity
170                  At present, the change from a desired phenotype (e.g. altered expression of a specif
171 thod of library generation and selection for a desired phenotype directly in a mammalian system can b
172 eu to numerically expand CAR(+) T cells with a desired phenotype, for the addition of interleukin (IL
173 ose genes and traits that best contribute to a desired phenotype, ultimately throwing evolution into
174 can be manipulated to modulate cells towards a desired phenotype.
175 -1-mediated gene transcription) resulting in a desired phenotypic cellular change (inhibit LEF-1-driv
176 llow, to isolate dominant mutant clones with a desired phenotypic change.
177 can deploy a given subset of them to produce a desired phenotypic outcome without undesired cross tal
178 s can be designed to produce structures with a desired physical property rather than a specific shape
179 s more than what is required for reaching to a desired point in 3D space.
180 ither selectivity over other drug targets or a desired polypharmacology.
181              Thus, the ability to select for a desired population of cells within a recipient would b
182      By locally feeding carbon precursors to a desired position of a substrate composed of an optimiz
183 ioester and a nucleophilic 1,2-aminothiol at a desired position to examine their polymerization produ
184 nd perhaps unexpected amino acid variants at a desired position.
185 hich essential enzymes divert flux away from a desired product, as well as in the production of polyk
186 intermediate and improve the final titers of a desired product.
187 pregulated to produce a significant yield of a desired product.
188 re organics operate synergistically to yield a desired product.
189 in is sufficient for efficient generation of a desired product.
190  variability in a population of cells follow a desired profile.
191 e design methods have emerged, starting from a desired property and optimizing a corresponding chemic
192 echanism also decelerates DNA translocation, a desired property for sequencing and gene detection, al
193 hich will improve not only the production of a desired protein but even more importantly, shed additi
194 n some cases, be achieved by optimization of a desired protein in isolation, methods have been develo
195 rvested, transfected, and induced to express a desired protein or selection of proteins to have medic
196 r the facile site-selective glycosylation of a desired protein with variously sized glycans.
197 ith tethered subunits which, while producing a desired protein, could be excluded from general transl
198 that can dramatically affect the fidelity of a desired quantum operation or measurement.
199 hich can be used to transform materials into a desired quantum state.
200                       We thus managed to map a desired radiation dose distribution from a patient's P
201  simultaneously, one before the other, or in a desired ratio.
202 ict the rate-determining transition state of a desired reaction in presence of the optimal arrangemen
203 ity of a phosphine ligand that best promotes a desired reaction outcome is often non-intuitive, and t
204 g the stabilities of intermediates to favour a desired reaction pathway can improve selectivity(3-5),
205 and modification of their properties towards a desired reactivity is, at best, complex.
206   Yet, safe, effective pill retention within a desired region of the GI remains an elusive goal.
207 mized and is very straightforward, providing a desired reproducibility in measurements, while not req
208 nd hence a drying end point determination to a desired residual moisture level.
209 o determine the optimal sequencing depth for a desired resolution.
210 olymer and crosslinker components to achieve a desired response at the site of action, which imparts
211 ol both the activation and the inhibition of a desired response function (protein activity or spine v
212 ation, nor is it practical to wait years for a desired response.
213 ing a broadband low-loss optical device with a desired response.
214 e them in a logical manner before initiating a desired response.
215 of mild model-engineered feedback to achieve a desired response.
216 times possible to tune the regiochemistry to a desired result by modifying reaction conditions.
217 lanning: They compute the difference between a desired reward and the reward expected from the curren
218 ccuracy of the classifier and thereby choose a desired risk of error.
219 ivery system for silencing and/or expressing a desired RNA for therapeutic purposes.
220 nic myelogenous leukemia and GIST has become a desired route to regulatory approval of an increasing
221 in a metabolic pathway for the production of a desired secondary metabolite.
222                    For the multicolor assay, a desired selection substrate was used simultaneously wi
223         It was confirmed that the search for a desired separation rarely requires a large number of c
224 rtificial transcription factors that bind to a desired sequence.
225                               The design for a desired shape is made by raster-filling the shape with
226                                              A desired shape, drawn on the canvas, is then produced b
227 ential of a cell, calculating the current of a desired simulated component using an appropriate model
228  swelling of the particles to microgels with a desired size and deformability.
229 hesize nanowires directly on substrates with a desired size and density.
230                 Maximizing the production of a desired small molecule is one of the primary goals in
231  to select aptamers with binding affinity to a desired small molecule.
232  epsilon-amine, (ii) Fmoc-SPPS elongation of a desired solubilizing sequence, and (iii) in-solution r
233 ch enable normal-hearing listeners to select a desired sound source out of a sound mixture.
234  (ii) multilayered slabs designed to achieve a desired spatial Green's function.
235 control the contact angles, thereby imposing a desired spatio-temporal stiffness variation to the pho
236 es sense for studying tumor heterogeneity or a desired special cell from a mixture cell sample such a
237 engineer the formation of micro emulsions to a desired specification.
238 at ensures the identification of clones with a desired specificity by properly positioning the random
239 rithms for finding metabolic pathways, given a desired start and target compound, that conserve a giv
240 n) nodes is required to steer the network to a desired state within a relatively small time window.
241 ering engineered and natural systems towards a desired state, a framework to control complex self-org
242 nodes and the minimum time required to reach a desired state.
243 en) nodes to steer a complex network towards a desired state.
244 was the number of patients needed to achieve a desired statistical power.
245 ons strategies forcing a set of targets into a desired steady state.
246  network in order to force it to converge to a desired steady-state distribution of gene regulation.
247 eated using colloids that self-assemble into a desired structure by means of a programmable recogniti
248                             A user specifies a desired structure, and the system automatically genera
249 trands to fold one long scaffold strand into a desired structure, has provided access to megadalton-s
250  the ability to control the system to obtain a desired structure.
251 activity of large collections of enzymes for a desired substrate holds great promise in the field of
252 etween proteins, engineer enzymes to achieve a desired substrate specificity, and develop drugs with
253 for designing proteins that self-assemble to a desired symmetric architecture.
254  discover which nanoparticle designs lead to a desired system behavior.
255 em components whose perturbation can lead to a desired system response, therefore facilitating the de
256 oral field and arriving after propagation as a desired target field, such as a spatiotemporal focus.
257 he initial surface so the evolution leads to a desired target pattern.
258 s used to discover peptides or proteins with a desired target property-most often, affinity for a tar
259 ary pressure either to favor the cleavage of a desired target sequence or to disfavor the cleavage of
260 ose native cleavage site is a close match to a desired target sequence, followed by small-scale engin
261 CR reactions to identify droplets containing a desired target sequence.
262 l systems, and allows bringing the system to a desired target state even when this state is not direc
263  be used to bias the helix population toward a desired target.
264 to an episodic memory that allows it to find a desired target.
265 framework permits reprogramming a network to a desired task, as well as rescuing networks from the br
266 cation model based on drugs with and without a desired therapeutic effect.
267 es drug-protein interactions associated with a desired therapeutic effect.
268 enes vaccine immunization regimens to elicit a desired therapeutic effect.
269 y are targeted by a drug is key to achieving a desired therapeutic response.
270 distribution, confirming its high quality as a desired therapeutic.
271                      This combination allows a desired time-temperature response to be achieved, to a
272  kinetic prevention of protein adsorption in a desired timescale is shown.
273 ed non-coding elements (CNEs) likely to have a desired tissue-specificity based on the expression of
274 hylactic antibodies against Ft by suggesting a desired topology for binding of the antibody to intern
275 bited not only potent CB1R activity but also a desired tPSA value over 90 A(2), a threshold considere
276 bility of several of these proteins might be a desired trait as part of a mechanism enabling Chlamydo
277 ncomycin, metronidazole, and fidaxomicin) is a desired trait in such probiotic species, we screened s
278 eased copy of each gene and/or operon has on a desired trait or phenotype.
279                           How best to evolve a desired trait?
280 ave like a trajectory controller but only if a "desired trajectory" is the goal of the task.
281 or control is that the motor system computes a "desired trajectory" when reaching to a spatial goal.
282 ant savings in time and materials to achieve a desired transformation with high efficiency.
283 tain the highest enantiomeric excess (ee) of a desired transformation.
284 he ionizable hydrophobic block, which led to a desired transition pH based on standard curves.
285 o enrich HIV-1-based lentiviral vectors with a desired transmembrane protein.
286 ved, then adjust command strength to achieve a desired travel distance.
287 okinetic (PBPK) modeling considering, first, a desired tumor control probability (TCP) of 99% and, se
288 s aminoacylate an amber suppressor tRNA with a desired unnatural amino acid, but no natural amino aci
289 y complicate engineering the biosynthesis of a desired "unnatural product" but may also open addition
290 ., for regulation that achieves or maintains a desired, useful end.
291  such as liposomes and polymers, can achieve a desired vaccine response.
292 y along a single Si nanowire can be tuned to a desired value (between crystalline and amorphous limit
293 over, its Poisson's ratio can be designed at a desired value, e.g. positive, or negative, or zero.
294 ssipative) such that a chosen target reaches a desired value.
295 PS) architecture that autonomously generates a desired ventilatory pattern in response to dynamic cha
296 airway pressure that would place the lung at a desired volume on its P-V curve.
297 ocompatible material that can be inflated to a desired volume using biocompatible effervescent chemic
298 livery system enables addition and mixing of a desired-volume droplet with the levitated drop.
299 ion and ~98% absorption of incident light at a desired wavelength.
300 urface-enhanced Raman spectroscopy (SERS) is a desired, yet unfulfilled, ability that could enable a

 
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