ライフサイエンスコーパス: aberrantly

1 ndensates constitutively binding actin moved aberrantly.

2 Thus, active GSK3beta phosphorylates Tau aberrantly.

3 east, lung, and colon cancers expressed GARP aberrantly.

4 It is likely that the aberrantly accelerated MMP-9 proteolysis during neurogen

5 ssing a catalytically inactive TRIM32 mutant aberrantly accumulate alpha- and beta-dystroglycan and a

6 They express high levels of CXCR3, aberrantly accumulate at the cortico-medullary junction

7 es in intracellular loop three causes Smo to aberrantly accumulate in cilia without pathway activatio

8 Rad18-deficient fibroblasts aberrantly accumulated DNA damage markers after DMBA tre

9 uggesting that pharmacological inhibition of aberrantly accumulated Rock2 may be a suitable therapeut

10 Bioimaging analysis showed that the mutant aberrantly accumulated Zn in enlarged and transit vascul

11 ites are conventional metabolites that, when aberrantly accumulated, have pro-oncogenic functions.

12 est identify and target stem-like mechanisms aberrantly acquired by cancer cells has been challenging

13 lassical host cellular receptor signaling to aberrantly activate Akt and drive survival of infected m

14 g, the CRAF fusions QKI-RAF1 and SRGAP3-RAF1 aberrantly activate both the MAPK and phosphoinositide-3

15 ating autoimmune disease is the potential to aberrantly activate CD4(+) T cells due to cross-recognit

16 ations within noncoding genomic regions that aberrantly activate oncogenes have remained poorly chara

17 r how approximately 90% of human cancers can aberrantly activate telomerase.

18 monly associated with BRAF gene fusions that aberrantly activate the mitogen-activated protein kinase

19 Overexpression of pstSCAB does not aberrantly activate the phosphate-responsive two-compone

20 ve implications for B-cell malignancies that aberrantly activate this pathway.

21 These observations suggest that aberrantly activated "AKI" pathways may drive pathogenes

22 ators of Transcription (JAK/STAT) pathway is aberrantly activated and contributes to ADPKD pathogenes

23 e for branched-chain amino acids (BCAAs), is aberrantly activated and functionally required for chron

24 Developmental signals are aberrantly activated and stem cell functions are disrupt

25 ment of new strategies to selectively target aberrantly activated B cells and restore normal B-cell h

26 Simultaneous inhibition of aberrantly activated BRAF and knockdown of miR-3151 pote

27 the cell that occurs when these pathways are aberrantly activated either in the absence of stress or

28 The hedgehog (Hh) signaling pathway is aberrantly activated in a majority of basal cell carcino

29 The Ras proteins are aberrantly activated in a wide range of human cancers, o

30 We found that HOTTIP is aberrantly activated in acute myeloid leukemia (AML) to

31 Hedgehog pathway signalling is aberrantly activated in around 95% of tumours.

32 ntral regulator of cell growth that is often aberrantly activated in cancer.

33 esses during metazoan development and can be aberrantly activated in cancer.

34 rowth, proliferation, and metabolism that is aberrantly activated in cancers and certain cancer-assoc

35 stinal stem cell (ISC) proliferation, and is aberrantly activated in colorectal cancer.

36 beta-catenin signaling is aberrantly activated in different gastrointestinal cance

37 nd a crucial signalling hub in many pathways aberrantly activated in disease.

38 pment and tissue regeneration, thought to be aberrantly activated in epithelial-derived cancer and ha

39 rols potassium balance in health and becomes aberrantly activated in FHHt.

40 insulin-like growth factor (IGF) pathway is aberrantly activated in HCC by IGF2 overexpression.

41 analyses to demonstrate that mast cells are aberrantly activated in human and murine osteoarthritic

42 ate that the RANK and NF-kappaB pathways are aberrantly activated in luminal progenitor cells residen

43 essential for intestinal homeostasis and is aberrantly activated in most colorectal cancers (CRC) th

44 TET1ALT is aberrantly activated in multiple cancer types including

45 ll-specific protein-tyrosine kinase (LCK) as aberrantly activated in PPR patients.

46 The transcription factor STAT3 is aberrantly activated in several tumors, where its consti

47 The Wnt/beta-catenin signaling pathway is aberrantly activated in the majority of colorectal cance

48 ion is normally restricted to germ cells yet aberrantly activated in tumors, where their functions re

49 In CRPC, AR is often aberrantly activated independent of androgen.

50 Most tumours have an aberrantly activated lipid metabolism(1,2) that enables

51 ream of and downstream from her-1 to prevent aberrantly activated male developmental programs in herm

52 Aberrantly activated RET is found in several types of hu

53 Our findings demonstrate that aberrantly activated SE upregulates CHPT1 expression and

54 F-producing CD4(+) T cells in AIH seem to be aberrantly activated Th1 cells.

55 When aberrantly activated, Gfi1 may function as a weak oncopr

56 arget of rapamycin (mTOR) signaling is often aberrantly activated, particularly when genetically alte

57 hanism for early dissemination in which Her2 aberrantly activates a program similar to mammary ductal

58 onal profiling demonstrates that mutant NSD2 aberrantly activates factors commonly associated with ne

59 3, which in turn re-phosphorylates STAT3 and aberrantly activates STAT3 target genes, leading to bort

60 nhanced regeneration of injured DRs, without aberrantly activating SCs and axons in intact nerves.

61 By aberrantly activating the RAF-MEK-ERK signaling pathway,

62 ng maturation, leading to the degradation of aberrantly active species that do not become autoinhibit

63 findings suggest that the mutant LRSAM1 may aberrantly affect the formation of transcription machine

64 tau can aberrantly aggregate into pathological inclusions that d

65 The accumulation of aberrantly aggregated MAPT (microtubule-associated prote

66 g evidence links cancer-related mutations to aberrantly altered condensate assembly, suggesting that

67 ndings reveal that chronic e-cigarette vapor aberrantly alters the physiology of lung epithelial cell

68 The mutant NC progenitors migrate aberrantly and fail to differentiate appropriately.

69 alpha-Synuclein aberrantly binds and deactivates ykt6 in patient-derived

70 cis-X first finds aberrantly cis-activated genes that exhibit allele-speci

71 In patient tissue, desmosomal proteins were aberrantly clustered and patient IgG colocalized with ma

72 However, Cdc42p was aberrantly colocalized with Fus2p to form a focus in mid

73 Furthermore, we show that ALS-associated FUS aberrantly contacts U1 snRNA at the Sm site with its zin

74 nt RNA present in the cell suspension can be aberrantly counted along with a cell's native mRNA and r

75 cal imaging revealed that neoarterioles were aberrantly covered by smooth muscle cells, with increase

76 HDAC8 aberrantly deacetylates p53 and promotes LSC transformat

77 We have demonstrated that SRSF1 levels are aberrantly decreased in T cells from patients with SLE a

78 Aberrantly differentially expressed genes (DEGs) were ob

79 frequently occurs following injury as cells aberrantly differentiate during tissue repair.

80 rowth, TGF-beta-responding progenies invade, aberrantly differentiate, and affect gene expression.

81 creatic progenitor; (3) immunogenic; and (4) aberrantly differentiated endocrine exocrine (ADEX) that

82 Often aberrantly displayed or found at atypical levels on canc

83 ns of MAP1B, another brain-enriched MAP, was aberrantly distributed in the soma and dendrites of muta

84 ng that normal epithelia may engulf and kill aberrantly dividing neighbours.

85 MLL4 expression is aberrantly down-regulated and BA homeostasis is disrupte

86 ver, the expressions of FGF21 receptors were aberrantly down-regulated in HFD rats.

87 While the expression of c-MYC can be aberrantly driven by genetic abnormalities, such as chro

88 activation and stability as a consequence of aberrantly elevated CK2 provoked by p53 ablation and irr

89 Aberrantly elevated expression in obesity of microRNAs (

90 small molecule IRAK1/4 inhibitor rescued the aberrantly elevated IL-1beta production in the JAK2-V617

91 ng the TGFbeta superfamily, all of which are aberrantly elevated in DND1-deficient PGCs.

92 port that the expression of the INTU gene is aberrantly elevated in human basal cell carcinoma (BCC),

93 genesis is normally tightly regulated but is aberrantly elevated in obesity.

94 ession of the immediate-early gene c-fos was aberrantly elevated in the Bdnf(+/-)dorsal striatum, and

95 Using mouse models, we reported that the aberrantly elevated neuronal PLD1 is key for oligomeric

96 ontent despite normal transcript levels, and aberrantly elevated phosphorylation on select mitochondr

97 Hrd1-mediated destruction of a protein that aberrantly engages the translocon (Deg1-Sec62) and subst

98 isease was accompanied by connexin-43 (Cx43) aberrantly enhanced in both cardiac and skeletal muscles

99 owever, inhibition of JNK signaling leads to aberrantly enhanced localization of E-cadherin at oocyte

100 ion; without Car4 ECs, the alveolar space is aberrantly enlarged despite the normal appearance of myo

101 , Rb1-mutant tumors are undifferentiated and aberrantly express homeobox gene clusters.

102 ial therapeutic targets in malignancies that aberrantly express LIN28.

103 tress tolerance may explain why many cancers aberrantly express MAGEs Here, we present an updated, co

104 e, we report that half of KRAS-mutant NSCLCs aberrantly express the homeobox protein HOXC10, largely

105 However, aberrantly expressed ALK is involved in the pathogenesis

106 ave applied small RNA sequencing to identify aberrantly expressed exosomal miRNAs as candidates for d

107 We find a median of one aberrantly expressed gene, five aberrant splicing events

108 Fs and epigenetic regulators associated with aberrantly expressed genes in pulmonary vascular cells i

109 interaction networks of proteins encoded by aberrantly expressed genes over signaling pathways assoc

110 A transcripts and 1109 mRNA transcripts were aberrantly expressed in 6- and 20-week-old db/db hearts

111 hed that low concentrations of myoglobin are aberrantly expressed in a significant proportion of brea

112 or tyrosine kinases, was identified as being aberrantly expressed in a significant proportion of HCC;

113 showed that TET2, EZH2, MAD2 and CDC20 were aberrantly expressed in AML patients.

114 Rac-guanine nucleotide exchange factor (GEF) aberrantly expressed in breast cancer.

115 osome organization, is frequently mutated or aberrantly expressed in cancer.

116 on, therefore we hypothesized that proteases aberrantly expressed in diabetic nephropathy (DN) may be

117 Many bromodomain-containing proteins are aberrantly expressed in diseases, as best studied in can

118 c MUC1-C transmembrane protein is, like MYC, aberrantly expressed in diverse human cancers.

119 many genes implicated in Wnt signaling were aberrantly expressed in Fancc(-/-) B cells.

120 tion of a stem cell regulatory gene which is aberrantly expressed in glioma and associated with patie

121 Long non-coding RNAs (lncRNAs) are often aberrantly expressed in Hepatocellular Carcinoma (HCC).

122 trogen-related receptor alpha (ERRalpha) are aberrantly expressed in human colon cell lines and tumor

123 SALL4 is aberrantly expressed in human myelodysplastic syndromes

124 CXCR4 is aberrantly expressed in immune-mediated diseases and its

125 ain a neural gene expression program that is aberrantly expressed in intellectual disability.

126 nd growth differentiation factors (GDFs), is aberrantly expressed in lower-risk MDSs and PMF.

127 miRNAs (microRNAs) are frequently and aberrantly expressed in many cancers.

128 However, it is also aberrantly expressed in many cancers.

129 N-Myc is a transcription factor that is aberrantly expressed in many tumor types and is often co

130 s an oncogenic transmembrane protein that is aberrantly expressed in MM cell lines and primary tumor

131 The protein Vav1 is aberrantly expressed in more than half of pancreatic can

132 lly expressed in immune cells but also found aberrantly expressed in multiple human carcinomas.

133 Germline genes that are aberrantly expressed in nongermline cancer cells have th

134 Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcinoma

135 cated in SCZ-associated genetic locus and is aberrantly expressed in patients with SCZ.

136 e show that the zinc finger protein ZBED2 is aberrantly expressed in PDA and alters tumor cell identi

137 apoptosis (Tweak) and its receptor Fn14 are aberrantly expressed in spinal astrocytes and skeletal m

138 th groups, whereas the CRABP2 and FABP5 were aberrantly expressed in the tumor cells of the sebaceous

139 Importantly, these GC-regulated genes are aberrantly expressed in TNBC patients and are associated

140 Many are reported to be aberrantly expressed in various cancers, including hepat

141 MUC5AC is a secretory mucin aberrantly expressed in various cancers.

142 Our study identifies a set of aberrantly expressed lincRNAs in breast cancer.

143 tly, our method can be applied to prioritize aberrantly expressed lncRNAs for functional validation i

144 Aberrantly expressed lncRNAs in HCC exert pleiotropic ef

145 We report, for the first time, aberrantly expressed lncRNAs in MDS and further prioriti

146 ment, it is becoming increasingly clear that aberrantly expressed MCPs can support multiple hallmarks

147 Previous studies suggest that aberrantly expressed Muc4 can influence the adhesiveness

148 the tandem repeat (TR) sequence of MUC4, an aberrantly expressed mucin in pancreatic adenocarcinomas

149 by activation of LGR4, an R-spondin receptor aberrantly expressed on MM cells.

150 Both of these truncated glycans are aberrantly expressed on the MUC1 glycoprotein in a spect

151 e employed microarray technology to identify aberrantly expressed plasma ECmiRNAs in CF and elucidate

152 cs and network analyses--that in human LSCs, aberrantly expressed proteins, in both imatinib-responde

153 results uncover a trans-dominant role for an aberrantly expressed RBFOX2(40) isoform in DM1 cardiac p

154 SOX9, a hair follicle growth regulator, was aberrantly expressed throughout the IFE of the mutant em

155 Mechanistically, we show that aberrantly expressed TWIST1 and BET protein BRD4 coopera

156 specific TE methylation and demethylation of aberrantly expressed young LINE-1s in normal tissues.

157 kers for pathologies in which miR levels are aberrantly expressed, such as cancer.

158 genes, including extra-embryonic genes, are aberrantly expressed.

159 al transcription termination factor MOC1 and aberrantly expresses the mitochondrial genome, resulting

160 ctin positioning to a myosin-blocking state, aberrantly favoring muscle relaxation, thus mimicking th

161 uL4 reveal a misassembled NPET, including an aberrantly flexible ribosomal RNA helix 74, resulting in

162 ry, which proposes that HLA-B27 heavy chains aberrantly form homodimers, is a central hypothesis that

163 The aberrantly formed dsRNAs were long, highly m(6)A modifie

164 Recent findings identify aberrantly functioning cilia as a possible source for CH

165 T cells directed against Tn-MUC1 and present aberrantly glycosylated antigens as a novel class of tar

166 ins potential glycosylation sites, which are aberrantly glycosylated during expression in eukaryotic

167 This work defines a critical role for aberrantly glycosylated MUC1 and identifies an activatin

168 Immunity in which they describe targeting of aberrantly glycosylated tumor-associated cell membrane m

169 67 mutant cerebella were hypoplastic and had aberrantly high canonical Wnt/beta-catenin signalling, p

170 Aberrantly high circulating ERFE in conditions of stress

171 he loss of wdb/PP2A function cooperates with aberrantly high Cyclin E protein levels, allowing cells

172 reflected in HSPC-derived cells, which show aberrantly high expression of m1 and m3 under androgen d

173 Here, we initially observed aberrantly high expression of protein kinase Calpha (PKC

174 Aberrantly high FOXP1 expression is frequently observed

175 al center B-cell (GCB) DLBCL cell lines with aberrantly high FOXP1 levels; S1PR2 expression is furthe

176 antageous in saturated conditions and causes aberrantly high growth rates in yeast that are chronical

177 cinoma, and neoplasia in mouse prostate with aberrantly high levels of Ube2e1 in the cytoplasm.

178 ts in recently experienced stimuli acquiring aberrantly high salience.

179 The aberrantly high Smad3 phosphorylation levels and SBE act

180 ngosine-1-phosphate lung levels, which, when aberrantly high, contribute to lung fibrosis, maladaptiv

181 MD6 (FERM domain-containing protein 6) as an aberrantly hypermethylated and significantly downregulat

182 led that the WNT pathway antagonist FRZB was aberrantly hypermethylated and underexpressed in MDS str

183 yonic developmental programs are reactivated aberrantly in adult organs to drive repair and regenerat

184 selectively in the mammalian brain but also aberrantly in cancer cells.

185 s a novel oncoprotein, gankyrin is expressed aberrantly in cancers from several different sites and h

186 e found that Ras/ERK activities are elevated aberrantly in p120RasGAP-deficient neurons.

187 and sensory axons wander, branch and sprout aberrantly in register with altered anterior-posterior h

188 naling in vascular disease, is overexpressed aberrantly in some breast cancers.

189 affic to the plasma membrane and accumulates aberrantly in the cytoplasm in RalA disrupted embryos.

190 ession of H19 long noncoding RNA (lncRNA) is aberrantly increased in UFs.

191 Aberrantly increased NF-kappaB O-GlcNAcylation has been

192 nts in cellular proliferation and death, but aberrantly increased protein kinase B (AKT) phosphorylat

193 itro mimicking of haploinsufficiency of PIN1 aberrantly increases tau phosphorylation and aggregation

194 ed to dysregulation of DISC1-PDE4 complexes, aberrantly increasing the activity of PDE4.

195 PIK3CD GOF mutations aberrantly induce exhaustion, senescence, or both and im

196 In the absence of T-bet, IFN-gamma aberrantly induced a type I IFN transcriptomic program.

197 mulation and immunoglobulin A production and aberrantly induced the transcription factor Foxo1.

198 F10 constitutively activate transcription by aberrantly inducing both AEP-dependent transcriptional a

199 une cells associated with acute inflammation aberrantly infiltrated into reproductive organs of pregn

200 peripheral branching, to a thin nerve, which aberrantly innervates the lateral rectus (as seen in Dua

201 utant, but not wild-type, GlyRS was shown to aberrantly interact with the Trk receptors and cause mis

202 its other CR components to nodes, pulls Cdr2 aberrantly into the CR, and reduces rates of CR maturati

203 d with horizontal cell axonal processes that aberrantly intrude into the outer nuclear layer.

204 hough components of the ciliary rootlet were aberrantly localized away from the base of the cilium.

205 t this pathway is also activated by host DNA aberrantly localized in the cytosol, contributing to inc

206 ning OM lipid asymmetry via the transport of aberrantly localized phospholipids (PLs) from the OM to

207 l experiments demonstrated that voltage from aberrantly located preretinal neovascular complexes is t

208 retrotransposon proliferation, resulting in aberrantly long telomeres.

209 In AD lesional skin, miR-335 expression is aberrantly lost.

210 SIRT1 function is aberrantly low in obesity, so understanding the underlyi

211 Importantly, at co-regulated genes, aberrantly methylated bases accumulate towards the 3'end

212 y transcribing chromatin and reveal roles of aberrantly methylated bases in regulation of gene expres

213 We found that aberrantly methylated CpGs are enriched in regulatory re

214 Pathway analysis indicated that aberrantly methylated DEGs mainly associated with the P1

215 lycosylase (AAG) is essential for removal of aberrantly methylated DNA bases.

216 studies (EWAS) have successfully identified aberrantly methylated genes in many diseases and disorde

217 of the dual-specificity phosphatase DUSP4 is aberrantly methylated in nodal and extranodal DLBCL, irr

218 er apical E-cadherin and F-actin levels, and aberrantly mobile Rho-kinase structures.

219 th immune and mitochondrial function, and is aberrantly modified post-translationally.

220 sease (AD) are marked by the accumulation of aberrantly modified tau proteins.

221 fied an HDAC6-chaperone complex that targets aberrantly modified tau.

222 al-epithelial paracrine signaling, which can aberrantly modulate cellular proliferation and tumorigen

223 1 mutants, abnormal gene expression leads to aberrantly motorized corticocortical and corticofugal ou

224 r amino acid 807 causes the C region to form aberrantly multimeric and aggregated complexes with an u

225 ned using a limited panel of substrates that aberrantly occupy the channel.

226 arch often discover important genes that are aberrantly over- or under-expressed in disease.

227 TRPM7 is aberrantly over-expressed in lung, liver and heart fibro

228 epidermal growth factor receptor (HER) 3 is aberrantly overexpressed and correlates with poor progno

229 pressed during mammary gland development and aberrantly overexpressed in aggressive 'basal' subtype b

230 ion is rare in human AML; instead, ALKBH5 is aberrantly overexpressed in AML.

231 The oncogenic MUC1-C protein is aberrantly overexpressed in diverse carcinomas; however,

232 tocellular carcinoma) receptor B4 (EPHB4) is aberrantly overexpressed in human colon tumor cell lines

233 MUC1) is a heterodimeric oncoprotein that is aberrantly overexpressed in most TNBC.

234 found that 24 PCD stage-specific miRNAs are aberrantly overexpressed in multiple myeloma (MM) tumor

235 Mucin 1 (MUC1) is aberrantly overexpressed in NSCLC, activates the nuclear

236 We show that the AP-1 family member FRA2 is aberrantly overexpressed in SMARCA2 mutant NPCs, where i

237 Although EGFL7 is aberrantly overexpressed in solid tumors, its role in le

238 growth factor and anchorage stimulation, is aberrantly overexpressed or activated in most solid tumo

239 ale pluripotent cells, while Tsix expression aberrantly persisted during differentiation.

240 on trapping mediated by the NF186 ectodomain aberrantly persists into adulthood, whereas the cytoplas

241 phosphorylation was increased, but STAT5 was aberrantly phosphorylated in response to IL-2 stimulatio

242 mmon drug used for restoring the function of aberrantly phosphorylated proteins in lung cancer.

243 t at 8 h post IR, BRCA1 foci are smaller and aberrantly positioned compared to control cells.

244 Aberrantly processed or mutant proteins misfold and asse

245 e oncogenic U2AF35(S34F) mutant and identify aberrantly processed pre-mRNAs by deep sequencing.

246 However, the translocated ATF6alpha becomes aberrantly processed preventing release of the soluble t

247 essional antigen-presenting cells, it can be aberrantly produced by other cell types, including hepat

248 nducing senescence-mediated growth arrest in aberrantly proliferating Nf1-/- SC.

249 alterations, including SETDB1 amplification, aberrantly promote AKT methylation to facilitate its act

250 a complex with the SOS allosteric site, thus aberrantly promoting SOS autoactivation, resulting in th

251 that is primary restricted to germ cells and aberrantly reactivated in various cancers.

252 Aberrantly rearranged immunoglobulin (Ig) alleles are fr

253 MLL-AF9 and other MLL fusion proteins aberrantly recruit epigenetic regulatory proteins, inclu

254 These results were consistent with aberrantly reduced stromal cell proliferation and comple

255 re, we find that the oncofetal HMGA2 gene is aberrantly reexpressed in many tumor types together with

256 ACLY is aberrantly regulated in many cancers, cardiovascular dis

257 WNT pathways are aberrantly regulated in multiple tumor types (albeit in

258 rtant regulators of gene expression that are aberrantly regulated in several inflammatory and infecti

259 egulating cellular growth and metabolism, is aberrantly regulated in the pathogenesis of a variety of

260 Accumulating evidence on aberrantly regulated ncRNAs, including short microRNAs,

261 rs of the salivary gland and highlight known aberrantly regulated pathways of diseases affecting the

262 or alpha (PDGFRalpha) signaling, which, when aberrantly regulated, is associated with developmental d

263 egeneration but may also cause fibrosis when aberrantly regulated.

264 ether, these findings indicate that LSCs are aberrantly reliant on cysteine to sustain energy metabol

265 We found that PRC2 target genes were aberrantly repressed in WT1mut AML, and that expression

266 Pdx1(-/-) microlumen diameters expand aberrantly, resulting in failure of epithelial tubulogen

267 rovide evidence that FUS protein binds to an aberrantly retained intron within the SFPQ transcript, w

268 any hereditary diseases, the spliceosome can aberrantly select nearby pseudo- or "cryptic" splice sit

269 The aberrantly shaped cores in ALLINI-treated particles can

270 We conclude that pre-existing hypertension aberrantly shifts nociceptive pulmonary-cardiac reflexes

271 SS18-SSX is able to directly recruit PRC2 to aberrantly silence target genes.

272 continuity, form when elimination of single, aberrantly specified cells fails and cells proliferate t

273 Juxtaposition of wild-type and aberrantly specified cells induces enrichment of actomyo

274 The aberrantly spliced adgra2 transcript found in ouchless m

275 ualized Medicine, LeafCutterMD recovered all aberrantly spliced genes that had previously been identi

276 ly, a number of these coregulated events are aberrantly spliced in mouse models and human patients wi

277 2-dependent introns have been reported to be aberrantly spliced in patient cells and animal models.

278 and ex vivo transcript analysis revealed an aberrantly spliced transcript, with intron 44 retained i

279 erence we attribute to preferential decay of aberrantly spliced transcripts.

280 junctions independently of mechanical inputs aberrantly stabilizes adhesion, arresting cell rearrange

281 its activity, as inactive SnRK1 variants are aberrantly stable but recover normal degradation when ex

282 Consequently, GFP-tagged Drp1 constitutes aberrantly stable, GTP-resistant supramolecular assembli

283 Aberrantly stalled ribosomes initiate the ribosome-assoc

284 ing mechanism is exploited by tumor cells to aberrantly sustain transcriptional programs commonly dys

285 Consistent with this, we found aberrantly sustained emergency granulopoiesis in a murin

286 In this study, we found aberrantly sustained granulocyte production in Icsbp(-/-

287 n IFT20-depleted cells, PDGFRalpha localizes aberrantly to the plasma membrane and is overactivated a

288 ogenic MPZ mutations, but is instead in part aberrantly trafficked to non-myelin plasma membranes and

289 t fail to terminate (readthrough genes), are aberrantly transcribed due to upstream termination failu

290 methylation at the promoter regions of genes aberrantly transcribed following l-DOPA treatment.

291 lation at many important regulatory areas of aberrantly transcribed genes.

292 -10) tumors, the growth factor gene Igf2 was aberrantly up-regulated, and ectopic Igf2 overexpression

293 Runx3-deficient CD8(+) TEFF cells aberrantly upregulated genes characteristic of follicula

294 ) and its product hydrogen sulfide (H2S) are aberrantly upregulated in colorectal cancers, where they

295 nd that a subset of ribosome-bound mRNAs was aberrantly upregulated in hippocampal CA1 neurons of Mec

296 iter lysine-specific demethylase 1 (LSD1) is aberrantly upregulated in many cancer types and its over

297 uclear receptor tyrosine kinases (nRTKs) are aberrantly upregulated in many types of cancers, but the

298 Lin28B is aberrantly upregulated in the childhood tumor neuroblast

299 At the same time, Runx2 is aberrantly upregulated in the medial layer of db/db aort

300 permits a constitutive enhancer to interact aberrantly with the receptor tyrosine kinase gene PDGFRA